P7 - Articles - LIDSEN Publishing Inc.丨The Open Access Publisher

Table of Content

Open Access Review

Neurotoxicity Following Exposure to Micro and Nanoplastics

Mojtaba Ehsanifar and

Zeinab Yavari

Received: 13 December 2024; Published: 16 March 2025; doi: 10.21926/obm.neurobiol.2501277

Abstract

The pervasive presence and enduring existence of micro and nanoplastics in the environment render their exposure to humans and aquatic creatures unavoidable. Research indicates these tiny plastic particles can be taken in by aquatic beings and mammals. Once within the body, micro and nanoplastics have the capability to infiltrate the brain, although the level of penetration and the subsequent neurotoxic effects are not fully explored. Previous studies indicate that metal (oxide) nanoparticles can enter the brain an [...]

2680 16706

Open Access Original Research

A Systems Biology Approach to Understanding Delirium Pathophysiology and Identifying Natural Compounds for Potential Therapeutic Purposes

Babak Sokouti

Received: 30 October 2024; Published: 14 March 2025; doi: 10.21926/obm.neurobiol.2501276

Abstract

Delirium is an acute neurocognitive disorder marked by disruptions in attention, cognition, and awareness, particularly prevalent among older and critically ill patients. This study applies a systems biology framework to dissect the molecular underpinnings of delirium and evaluate natural compounds for potential therapeutic roles. Through bioinformatics analyses, key biomarkers related to delirium, including IL6, AKT1, JUN, APP, and PPARGC1A, were identified, implicating pathways tied to neuroinflammation, oxidativ [...]

864 5466

Open Access Original Research

Studying the Cognitive and Behavioural Dynamics of Psychopathy

Liana Spytska

Received: 04 December 2024; Published: 14 March 2025; doi: 10.21926/obm.neurobiol.2501275

Abstract

The relevance of studying the cognitive and behavioral dynamics of psychopathy lies in its importance for improving diagnosis, therapeutic interventions, and reducing crime, thereby contributing to public safety. This study aimed to investigate how cognitive and behavioral mechanisms influence psychopathy. A combination of methods was employed, including the Levenson Self-Report Psychopathy Scale, semi-structured interviews, and the analysis of non-verbal reactions. The sample consisted of eight participants (four [...]

841 11047

Open Access Original Research

A Pilot Double-Blind Randomised Sham-Controlled Trial of Paraesthesia-Free Burst Waveform Spinal Cord Stimulation in a Small Case Series of Patients with Chronic Spinal or Limb Pain

John Salmon and

Peter D. Drummond

Received: 24 November 2024; Published: 05 March 2025; doi: 10.21926/obm.neurobiol.2501274

Abstract

The aim of this study was to identify methodological issues that might influence comparison of burst versus sham spinal cord stimulation for treating chronic pain. Six patients with an implanted BurstDR spinal cord stimulator were assessed double-blind during eight 3-to-4-day ON or OFF cycles over a 28-day period. The stimulator was switched off during two randomly selected cycles. Pain intensity was the primary outcome, and secondary outcomes included analgesic consumption, activity estimation and sleep quality. T [...]

402 2907

Open Access Review

The Impact of Microbiota on Neurological Disorders: Mechanisms and Therapeutic Implications

Giuseppe Merra ,

Giada La Placa ,

Marcello Covino ,

Marcello Candelli ,

Antonio Gasbarrini and

Francesco Franceschi

Received: 06 November 2024; Published: 28 February 2025; doi: 10.21926/obm.neurobiol.2501273

Abstract

Interactions in the gut-brain crosstalk have led to the development of an entirely new concept: the "microbiota-gut-brain axis". Microbiota has gained considerable attention in relation to disorders of a more neurological nature, such as neurodevelopmental and neuropsychiatric illnesses like autism spectrum disorder, anxiety, and mood disorders. This review aims to summarize the recent trends and insights into the role and consequences of gut microbiota in brain health and pediatric neurological disorders. Dysbiosi [...]

725 4576

Open Access Review

Therapeutic Exercise Holds the Key to Improve Hand and Upper Limbs Dystonia Rehabilitation Programs: A Systematic Review

Maria Vittoria Raele ,

Laura Dell’Anna ,

Rachele Mancini ,

Giacomo Farì ,

Maurizio Ranieri ,

Marisa Megna ,

Riccardo Marvulli ,

Marco Paoloni ,

Francesco Agostini ,

Massimiliano Mangone and

Andrea Bernetti

Received: 20 September 2024; Published: 27 February 2025; doi: 10.21926/obm.neurobiol.2501272

Abstract

Upper limb dystonia is a focal locomotion disorder affecting arm, forearm, and hand muscles, causing abnormal movements given by repeated, steady, and intercontinuous contractions. There are different types of dystonia and the multifaced nature of this pathology is challenging in the treatment management, leading to a worsening of affected patients’ life quality, mainly from a psychological point of view, but also from a functional perspective. This work examines the present literature regarding upper limb dystonia [...]

637 5532

Open Access Original Research

Digital Technology and Brain Development among Entrepreneurial Ambitions

Nadia A. Abdelmegeed Abdelwahed and

Muhammad Sufyan Ramish

Received: 20 October 2024; Published: 25 February 2025; doi: 10.21926/obm.neurobiol.2501271

Abstract

Brain development (BD) is an important factor. To effectively enhance BD, institutions employ digital tools, technology, and innovative digital competencies to improve students’ entrepreneurial ambitions. The present paper examines the role of digital technology in developing BD among entrepreneurial ambitions in Egypt. The study modes are quantitative and cross-sectional to collect data from the entrepreneurial aspirations of Egyptian universities where business, management, economics, and commerce students [...]

550 3533

Open Access Original Research

The Role of E-Learning Crack-Up Perception and Fear of Academic Year Loss in Students’ Psychological Distress and Academic Performance

Nadia A. Abdelmegeed Abdelwahed and

Muhammad Sufyan Ramish

Received: 27 October 2024; Published: 14 February 2025; doi: 10.21926/obm.neurobiol.2501270

Abstract

This study examines the effect of e-learning crack-up perception (ECUP) and fear of academic year loss (FAYL) on psychological distress (PD). The study also explores the impact of PD on students' academic performance (AP). It uses a quantitative method based on data collected from Egyptian medical university students using convenience sampling. The study utilized 313 cases to get the final results. Using path analysis through analysis of moment structures (AMOS) software, the study confirmed a positive effect o [...]

749 4978

Open Access Opinion

Understanding the Scope of the Contemporary Controversy about the Physical Nature and Modeling of the Action Potential: Insights from History and Philosophy of (Neuro)Science

Benjamin Drukarch and

Micha M.M. Wilhelmus

Received: 09 October 2024; Published: 13 February 2025; doi: 10.21926/obm.neurobiol.2501269

Abstract

According to mainstream neuroscience, the action potential (AP) is a purely dissipative electrical phenomenon that should be modeled as such. However, also (essentially) reversible mechanical, thermal, and optical changes in the neuron have been reported to accompany the movement of the AP along the axonal surface. These are not accounted for in the prevailing (bio)-electric theory of neuronal excitability, originally introduced by Hodgkin and Huxley (HH) and mathematically formulated in their famous HH model of th [...]

725 5008

Open Access Original Research

A New Technology System to Support Occupational Activity and Mobility in People with Severe-to-Profound Intellectual Disability and Blindness

Giulio E. Lancioni ,

Gloria Alberti ,

Chiara Filippini ,

Nirbhay N. Singh ,

Mark F. O’Reilly ,

Jeff Sigafoos and

Serafino Buono

Received: 14 October 2024; Published: 12 February 2025; doi: 10.21926/obm.neurobiol.2501268

Abstract

People with severe-to-profound intellectual disability and blindness tend to be sedentary and detached, given their orientation and mobility problems, often combined with their limited interest in their surroundings. An approach to address this problem may involve the use of technology systems guiding the participants through mobility and occupational activity (object use) with a combination of spatial/orientation cues, basic instructions for the responses required by the activity, and positive stimulation during t [...]

514 3426

Open Access Original Research

Measuring Post-Exertional Malaise with DePaul Symptom Questionnaires: Challenges and Opportunities

Leonard A. Jason

Received: 15 October 2024; Published: 05 February 2025; doi: 10.21926/obm.neurobiol.2501267

Abstract

Following mental or physical exertion, patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) experience Post-Exertional Malaise (PEM). Although self-report questions represent less expensive and invasive procedures to assess PEM, variability in the wording of the symptom can cause reliability and validity problems. If different PEM measures are used in studies, this could create difficulties in replicating findings, identifying biomarkers, and determining effective treatments for patients. The o [...]

1858 14989

Open Access Research Article

Exploring the Unidimensionality of the GAD-7 for South African First Responders: Evidence from Multiple Psychometric Approaches

Anita Padmanabhanunni and

Tyrone Pretorius

Received: 21 September 2024; Published: 27 January 2025; doi: 10.21926/obm.neurobiol.2501266

Abstract

Generalized Anxiety Disorder (GAD) is a prevalent mental health condition and the GAD-7 is widely used as a screening tool and measure of GAD severity. However, research has yielded conflicting findings regarding the factor structure of the instrument, with some studies supporting a unidimensional interpretation while others suggest a two-factor solution. These inconsistencies highlight the importance of validating the GAD-7 across diverse populations. This study aimed to assess the psychometric properties and fact [...]

682 4237

Open Access Review

Advancements in Silkworm-Derived Silk Fibroin Biomaterials for Peripheral Nerve Regeneration

Jitu Mani Das ,

Isha Behere ,

Jnanendra Upadhyay ,

Rajiv Borah and

Ganesh Ingavle

Received: 14 October 2022; Published: 20 January 2025; doi: 10.21926/obm.neurobiol.2501265

Abstract

Regenerating injured nerves is difficult because they have little spontaneous regeneration potential. Advances in tissue engineering and regenerative medicine have emphasized the possibility of biomaterial-based methods for nerve healing. Natural protein-based biomaterials have benefits over synthetic ones, such as biocompatibility, non-immunogenicity, and biodegradability. Silk fibroin, generated from mulberry and non-mulberry silkworms, is especially promising because of its abundance, simplicity of processing in [...]

1219 10059

Open Access Review

Unraveling the Impact of Modern Technologies on Young Minds: A Comprehensive Study

Hatef Pourrashidi Alibigloo

Received: 22 October 2024; Published: 13 January 2025; doi: 10.21926/obm.neurobiol.2501264

Abstract

The implementation of modern technologies has transformed connectivity, information-sharing, and education, significantly influencing students' academic journeys. New technologies offer advantages and disadvantages, particularly impacting young students and leading to changes in habits and behaviors. While technology can improve learning efficiency through personalized approaches, excessive screen time can negatively affect communication and academic performance. Studies recommend limited screen time for children t [...]

981 9163

Open Access Review

Reflexes and Shared Intentionality in the Origins of Emotions Development: A Scoping Review of Studies on Blinking in Infants

Igor Val Danilov and

Sandra Mihailova

Received: 16 August 2024; Published: 10 January 2025; doi: 10.21926/obm.neurobiol.2501263

Abstract

This review aims to explore research on the development of emotions in organisms at the simple reflexes substage of the sensorimotor stage of cognitive development. We review the literature on alterations in spontaneous blinking in children under 6 months of age. Then, we extract the data from the selected studies that allow us to examine whether simple reflexes in infants reveal the emotion signature in the altered reflective responses. The significance of this study is that it is the first review to demonstrate t [...]

554 7738

Open Access Editorial

Acknowledgment to Reviewers of OBM Neurobiology in 2024

OBM Neurobiology Editorial Office

Received: 03 January 2025; Published: 03 January 2025; doi: 10.21926/obm.neurobiol.2501262

Abstract

The editors of OBM Neurobiology would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2024. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers can download a certificate of recognition directly from our submission system. Additionally, reviewers can sign up to the Web of [...]

351 2186

Open Access Review

The Impact of Depressive and Anxiety Symptoms on Academic Achievement among Undergraduate University Students: A Systematic Review

Suheir Awadalla ,

E Bethan Davies and

Cris Glazebrook

Received: 21 October 2024; Published: 31 December 2024; doi: 10.21926/obm.neurobiol.2404261

Abstract

Numerous studies have explored the prevalence of depression and anxiety symptoms among university students worldwide. However, only a few have examined how these symptoms affect students' academic performance. This systematic review explores the relationship between depression, anxiety, and academic performance among undergraduate university students. Peer-reviewed articles published between 1997 and June 2020 were included if they: (a) were in English; (b) had a study population that was exclusively undergraduate [...]

1681 25180

Open Access Review

The Origin of Natural Neurostimulation: A Narrative Review of Noninvasive Brain Stimulation Techniques

Igor Val Danilov

Received: 08 September 2024; Published: 29 November 2024; doi: 10.21926/obm.neurobiol.2404260

Abstract

This narrative review of the literature on noninvasive brain stimulation techniques observes four neurostimulation domains: light therapy, photobiomodulation, a group of techniques within transcranial electric current and magnetic field stimulations, low-frequency sound stimulations, including vibroacoustic therapy, and rhythmic auditory stimulation. The review aims to determine whether or not different brain stimulation approaches rely upon a similar physicochemical sequence of actions. The study identifies releva [...]

1018 10459

Open Access Original Research

Factor Structure of Autism Symptoms in 5-6-Year-Old Children: Age Perspective

Andrey Nasledov ,

Liubov Tkacheva and

Sergey Miroshnikov

Received: 03 July 2024; Published: 27 November 2024; doi: 10.21926/obm.neurobiol.2404259

Abstract

The work identifies the factor structure of autism symptoms in older preschoolers to check their age dynamics. An Autism Marker Questionnaire containing 330 potential symptoms of autism spectrum disorder (ASD) was developed to be implemented as an online survey. 501 children were examined (371 with ASD) already classified by experts as a group of ASD, typically developing (TD) or with developmental delay (DD). At the exploratory stage, a relatively simple 8-factor structure was obtained: Speech Understanding (SU), [...]

613 5540

Open Access Review

Frontal Migraine Surgery: Indications and Results

Suat Morkuzu ,

Alice Morello ,

Giorgio Raposio and

Edoardo Raposio

Received: 18 July 2024; Published: 27 November 2024; doi: 10.21926/obm.neurobiol.2404258

Abstract

Recent studies have identified that certain types of migraines, including frontal migraines, may be attributed to the irritation of specific extracranial nerves. This systematic review addresses the following questions: Which surgical techniques are most effective for chronic frontal migraines? How do combined surgical approaches compare to isolated procedures regarding efficacy and complication rates? Our objective is to comprehensively analyze surgical options for frontal migraines, including their success rates [...]

786 5194

Open Access Review

Evaluating the Efficacy of Action Observation Training in Improving Upper Limb Functionality in Children with Cerebral Palsy: A Scope Review

Danilo Donati ,

Giacomo Farì ,

Federica Giorgi ,

Andrea Bernetti and

Roberto Tedeschi

Received: 02 June 2024; Published: 22 November 2024; doi: 10.21926/obm.neurobiol.2404257

Abstract

This review evaluates the efficacy of Action Observation Training (AOT) in improving upper limb functionality in children with cerebral palsy (CP). Five studies were selected based on strict inclusion criteria, focusing on clinical interventions that assessed AOT's effects on upper limb motor skills in pediatric CP populations. Across these studies, significant improvements were observed in motor skills such as reach, grasp, and spontaneous use of the affected limb, underscoring AOT's potential functional benefits. [...]

766 7870

Open Access Review

Genetic Basis of Emotional Regulation: Integrative Analysis of Behavioral and Neurobiological Data

Mykhailo Zhylin ,

Viktoriia Mendelo ,

Svitlana Bondarevych ,

Yuliia Kokorina and

Andrii Tatianchykov

Received: 08 July 2024; Published: 22 November 2024; doi: 10.21926/obm.neurobiol.2404256

Abstract

Emotional regulation (ER) is the process by which people change their physiology, expressions, and emotional experiences to operate in their daily lives. Deficits in emotion control may be connected to physical and mental health consequences. This review aims to identify genetic variants, understand neurobiological mechanisms, and explore behavioral phenotypes associated with ER. In our study, we included English studies from online databases such as Web of Science, Cochrane Library, Google Scholar, PubMed, and Sco [...]

2407 26097

Open Access Review

Effective Physiotherapy for Post-Concussion Recovery and Return to Sports: Narrative Review

Giacomo Farì ,

Roberto Tedeschi ,

Andrea Bernetti and

Danilo Donati

Received: 30 August 2024; Published: 20 November 2024; doi: 10.21926/obm.neurobiol.2404255

Abstract

Traumatic brain injury (TBI) caused by direct or indirect forces is a prevalent issue in contact sports, leading to symptoms such as headaches, dizziness, nausea, and neck pain. These symptoms can have long-term consequences, including neurodegenerative diseases and mood disorders. This review fills an essential gap in the literature, as current studies on physiotherapy for traumatic brain injury (TBI) in sports are limited in scope, particularly in evaluating multimodal and personalized interventions. The review a [...]

1372 8307

Open Access Review

Gut Microbiota and Neuroinflammation: An Interconnected Nexus of Health and Neurodegenerative Disease

Mega Obukohwo Oyovwi ,

Gregory Joseph Uchechukwu ,

Bolape Adeola Oyekanmi ,

Emmanuel Igho Odokuma and

Ugushida Thankgod Ogenma

Received: 08 June 2024; Published: 20 November 2024; doi: 10.21926/obm.neurobiol.2404254

Abstract

The gut microbiota, a complex ecosystem of billions of microorganisms in the human digestive tract, plays a crucial role in maintaining health. Recent studies have highlighted a bidirectional communication pathway called the gut-brain axis between the gut and the brain. This communication is significantly influenced by gut microbiota and its interactions with the immune system, which can affect brain function and contribute to inflammation. This study aims to provide a comprehensive overview of the relationship bet [...]

779 6521

Open Access Original Research

The Development of Operational Model Integrating Digital Technologies into Public Mental Healthcare Services in Nigeria

Olubunmi Yemisi Fashoto ,

Maureen Nokuthula Sibiya and

Olanrewaju Oladimeji

Received: 09 July 2024; Published: 08 November 2024; doi: 10.21926/obm.neurobiol.2404253

Abstract

The availability and utilization of digital technologies can leverage the challenges of the sharp-depleting workforce due to the consistent migration of healthcare professionals (HCPs), the alarming ratio of the number of patients to HCPs, discretional use of digital technologies among HCPs in providing effective therapeutic interventions and mental healthcare services. This study aimed to develop an operational model that integrates digital technologies in mental healthcare service delivery for public facilities i [...]

659 5084

Open Access Review

Relationship of Retroelements with Antiviral Proteins and Epigenetic Factors in Alzheimer's Disease

Rustam Nailevich Mustafin

Received: 10 August 2023; Published: 31 October 2024; doi: 10.21926/obm.neurobiol.2404252

Abstract

Genetic factors such as allelic variants of the PSEN1, PSEN2, APP, and APOE genes play an important role in Alzheimer's disease development. Still, they cannot explain all cases of the disease and cannot form the basis for effective treatment methods for the pathology. Alzheimer's disease is the most common neurodegenerative disease, so identifying new mechanisms of pathogenesis may reveal new ways of treating it. Since Alzheimer's disease is associated with aging, the hypothesis is proposed that an important trigg [...]

867 4300

Open Access Review

The Relationship between Emotional Intelligence and Bullying in Adolescents: A Scoping Review

Iyus Yosep ,

Ai Mardhiyah ,

Kurniawan Kurniawan and

Indra Maulana

Received: 21 July 2024; Published: 25 October 2024; doi: 10.21926/obm.neurobiol.2404251

Abstract

Bullying is a serious problem among adolescents with broad negative impacts on psychological and social well-being. Factors that influence bullying are individual and environmental. Emotional intelligence has been identified as an essential factor influencing bullying behavior, but its relationship is not fully understood. This research aims to conduct a scoping review of the relationship between emotional intelligence and adolescent bullying behavior. A scoping review approach was used in this research. Search for [...]

1154 19300

Open Access Original Research

Predictive Effect of Eco-Anxiety and Climate Change Anxiety towards Mental Health Problems and Psychological Well-Being among Entrepreneurs

Nadia A. Abdelmegeed Abdelwahed and

Muhammad Sufyan Ramish

Received: 25 July 2024; Published: 18 October 2024; doi: 10.21926/obm.neurobiol.2404250

Abstract

Entrepreneurs face massive challenges when attempting to create sustainable businesses in the current era. This juggling act leads to eco-anxiety and climate change anxiety, which mainly affect entrepreneurs by creating concerns and ruining creativity and progress. These issues contribute to individuals' mental health problems (MHP) and severely affect psychological well-being (PWB). With this in mind, the present study investigates the impact of eco-anxiety (EA) and climate change anxiety (CCA) on MHP and PWB [...]

905 11316

Open Access Case Report

Stuart Stress Adaptation and Nola Pender's Model on Mental Nursing Care of Patients Schizophrenia: Case Study

Rohman Hikmat ,

Iyus Yosep ,

Efri Widianti ,

Suryani Suryani ,

Aat Sriati and

Icih Susanti

Received: 20 July 2024; Published: 12 October 2024; doi: 10.21926/obm.neurobiol.2404249

Abstract

To describe the application of the Stuart Stress Adaptation and Nola Pender Models in mental nursing care for a patient with schizophrenia and risk of violent behavior. This research method used case studies. The sample is one patient with schizophrenia. Data collection is done through direct observation, interviews, and patient medical records. The results showed that the client showed a major nursing problem in the form of risk of violent behavior. Predisposing factors included passive childhood experiences and s [...]

924 10624

Open Access Review

Effectiveness of Integrating Botulinum Toxin Type A with Rehabilitative Strategies for Managing Spastic Diplegia in Children: Scope Review

Danilo Donati ,

Giacomo Farì ,

Federica Giorgi ,

Vincenza Amoruso ,

Valentina Boetto ,

Riccardo Marvulli ,

Laura Dell'Anna ,

Andrea Bernetti and

Roberto Tedeschi

Received: 31 May 2024; Published: 10 October 2024; doi: 10.21926/obm.neurobiol.2404248

Abstract

This review examines the effectiveness of integrating botulinum toxin type A (BONT-A) with various rehabilitative strategies in treating spastic diplegia in children. The studies analyzed consistently demonstrate significant reductions in spasticity and improvements in gait when BONT-A is combined with interventions such as intensive physical therapy, serial casting, electrical stimulation, physiotherapy, occupational therapy, and robotic-assisted gait training. The findings underscore the importance of personalize [...]

850 8673

Open Access Original Research

A Probiotic Mixture Decreases Neuropathy and Oxidative Stress Markers in Diabetic Rats

Mohammad Shabani ,

Elham Hassanpour ,

Fatemeh Aghighi ,

Mojgan Mohammadifar ,

Fereshteh Bahmani and

Sayyed Alireza Talaei

Received: 11 May 2024; Published: 30 September 2024; doi: 10.21926/obm.neurobiol.2403247

Abstract

Diabetic neuropathy (DN) is a type of nerve damage caused by long-term hyperglycemia in diabetes mellitus (DM). The gut microbiota alters in DM. Therefore, improvement of the gut flora may affect neuropathic pain and oxidative biomarkers' responsiveness to the probiotic treatment. The present study aimed to assess the effects of probiotic supplementation on neuropathic pain and oxidative stress biomarkers in diabetic rats’ serum. Forty-eight rats (200-250 g) were randomly divided into four groups (n = 12 [...]

537 5556

Open Access Original Research

Breaking Barriers: A Reliable Method for RNA Extraction in Zebrafish Neurodegenerative Research

Mahintaj Dara ,

Zahra Karimi ,

Mehdi Dianatpour and

Hadi Aligholi

Received: 02 June 2024; Published: 30 September 2024; doi: 10.21926/obm.neurobiol.2403246

Abstract

Zebrafish (Danio rerio) is a vertebrate with unique characteristics, making it an excellent biomedical research animal model. One research area involves investigating changes in gene expression during neurodegenerative processes, aging-related changes, and behavioral studies in zebrafish. To achieve this, high-quality and quantity RNA must be extracted from zebrafish. This study aims to develop an optimized RNA extraction method from zebrafish larvae brains. After rearing and maintaining the zebrafish in suitable c [...]

1343 6758

Open Access Original Research

Mental Hindrances and Entrepreneurial Supports towards Psychological Wellbeing among Entrepreneurs

Nadia A. Abdelmegeed Abdelwahed and

Muhammad Sufyan Ramish

Received: 21 May 2024; Published: 18 September 2024; doi: 10.21926/obm.neurobiol.2403245

Abstract

University entrepreneurs' psychological wellbeing (PWB) is a gigantic problem that substantially affects their academic performance, health, innovative capabilities, and more comprehensive societal contributions. In this study, we examine mental hindrances, such as stress, anxiety and depression and entrepreneurship-related constructs, such as entrepreneurial purpose (ENSE), entrepreneurial carefulness (ENSS) and entrepreneurial desire (ENRE) that predict PWB among Egyptian university entrepreneurs. In this quantit [...]

545 5792

Open Access Review

Illuminate Resection Pathways with Fluorescence Guidance in Glioma Surgery: Case Reports and Systematic Review

Manuel De Jesus Encarnacion Ramirez ,

Nikolay Konovalov ,

Stanislav Kaprovoy ,

Gennady Chmutin ,

Geovany Venegas Cerna ,

Renat Nurmukhametov ,

Andreina Rosario Rosario ,

Kalin Ivan Yakovlevich ,

Jesus Lafuente ,

Eric Suero Molina and

Nicola Montemurro

Received: 20 April 2024; Published: 09 September 2024; doi: 10.21926/obm.neurobiol.2403244

Abstract

Gliomas are the most common brain tumor in adults, with a poor prognosis despite intensive treatments. Complete surgical resection is difficult due to its infiltrative growth, but aggressive surgery improves outcomes. Fluorescence-guided surgery (FGS) is used to distinguish tumor tissue during surgery. 5-Aminolevulinic Acid (5-ALA) is a crucial fluorescent agent in FGS, transforming into a molecule that accumulates in tumor cells. We presented a 34-year-old female with a high-grade glioma in the left parietal lobe [...]

618 5694

Open Access Original Research

The Origin of Social Skills: Manipulating Shared Intentionality in Bioengineering Systems for Empathy Training

Igor Val Danilov and

Sandra Mihailova

Received: 12 March 2024; Published: 28 August 2024; doi: 10.21926/obm.neurobiol.2403243

Abstract

This pilot study (N = 28) aims to develop universal computer-aided empathy training. The experiment tests a research design of manipulating behavior in subjects toward non-affective cues in a bioengineering system. The study implements the Mother-Fetus Neurocognitive Model to involve subjects in subliminal cognitive collaboration with confederates, which enables subjects to associate the meaning of empathy with the picture only seen by confederates. The outcome shows the feasibility of the chosen research design wi [...]

682 4409

Open Access Original Research

Enhancing Students’ Brain Development through Technology Use and Digital Characteristics

Nadia A. Abdelmegeed Abdelwahed and

Muhammad Sufyan Ramish

Received: 12 May 2024; Published: 19 August 2024; doi: 10.21926/obm.neurobiol.2403242

Abstract

In the present era of digitalization, technology plays a prominent role in relaxation and brain development (BD), specifically for university students. The present study explores the impact of technology use and digital characteristics (DC) in developing students' BD. We applied the quantitative methods; the study collected 328 samples from Egypt's different public sector universities through a questionnaire. Using path analysis through analysis of moment structures (AMOS), the results demonstrate a positive effect [...]

684 4952

Open Access Original Research

Recognizing the Role of ChatGPT in Decision-Making and Recognition of Mental Health Disorders among Entrepreneurs

Nadia A. Abdelmegeed Abdelwahed

Received: 01 April 2024; Published: 19 August 2024; doi: 10.21926/obm.neurobiol.2403241

Abstract

Nowadays, mental health disorders have become a significant concern for everyone. There are diverse reasons emanating from the workplace, business, and everyday environment. Therefore, there is a current need to use technology to detect and review their symptoms and causes. Accordingly, in this study, the researcher attempted to recognize ChatGPT’s role in decision-making and the recognition of mental health disorders among Egyptian entrepreneurs. The researcher used a quantitative approach in this study based its [...]

956 7384

Open Access Review

Using Technologies to Promote Adaptive Responding and Reduce Challenging Behaviors in Children with Autism Spectrum Disorder: A Selective Review

Anna Passaro ,

Antonio Zullo ,

Mariacarla Di Gioia ,

Mirella Dragone ,

Khalida Akbar and

Fabrizio Stasolla

Received: 30 May 2024; Published: 15 August 2024; doi: 10.21926/obm.neurobiol.2403240

Abstract

The management and treatment of challenging behaviors in children diagnosed with Autism Spectrum Disorder (ASD) is a priority for caregivers, educators, and healthcare professionals. This selective review examined how different technologies were used to help manage challenging behaviors in children with autism, describing each technology's strengths, weaknesses, and applications. This paper aimed to provide accessible choices for caregivers, educators, and healthcare professionals, enabling them to make well-inform [...]

552 5209

Open Access Review

Oxidative Stress in Cerebral Ischemia/Reperfusion Injury

Roberto Anaya-Fernández ,

Roberto Anaya-Prado ,

Michelle M. Anaya-Fernández ,

Miguel A. Guerrero-Palomera ,

Ivan F. Garcia-Ramirez ,

Daniel Gonzalez-Martinez ,

Consuelo C. Azcona-Ramirez ,

Citlalli S. Guerrero-Palomera ,

Claudia Garcia-Perez ,

Bernardo Tenorio-Gonzalez ,

Jose E. Tenorio-Gonzalez ,

Laisha F. Vargas-Ascencio ,

Abraham I. Canseco-Villegas ,

Gustavo Servin-Romero ,

Allen R. Barragan-Arias and

Bruno Reyna-Rodriguez

Received: 02 May 2024; Published: 07 August 2024; doi: 10.21926/obm.neurobiol.2403239

Abstract

Oxidative stress in cerebral ischemia/reperfusion injury (CIRI) involves reactive oxygen and nitrogen species (ROS and RNS). Despite efficient antioxidant pathways in the brain, hypoxia triggers the production of oxygen free radicals and downregulates ATP, which leads to oxidative stress. Sources of free radicals during CIRI include Ca2+-dependent enzymes, phospholipid degradation and mitochondrial enlargement. Upon reperfusion, the abrupt increase of oxygen triggers a massive radical production via enzymes like xa [...]

913 7672

Open Access Review

Tau-Targeted Immunotherapy for Alzheimer's Disease: Insight into Clinical Trials

Nadia El Kadmiri

Received: 16 August 2023; Published: 07 August 2024; doi: 10.21926/obm.neurobiol.2403238

Abstract

The use of immunotherapy as a therapeutic approach to Alzheimer's Disease (AD) is gaining rapid interest, with the primary goal of targeting abnormalities that impact neuronal viability through specific antibodies. Currently, clinical strategies focus intensively on targeting the two main pathologies associated with AD, beta-amyloid (Ab) and tau. This review examines ongoing research in the realm of tau immunotherapy, including clinical trials that demonstrate promising potential for halting AD progression. Several [...]

764 12866

Open Access Original Research

COVID-19 Impact on Substance Use (Tobacco, Alcohol, Cannabis) and Stress in Medical Students

Mario Muselli ,

Loreta Tobia ,

Eleonora Cimino ,

Carlo Confalone ,

Martina Mancinelli ,

Leila Fabiani ,

Stefano Necozione and

Vincenza Cofini

Received: 30 March 2024; Published: 06 August 2024; doi: 10.21926/obm.neurobiol.2403237

Abstract

The COVID-19 pandemic has led to unprecedented challenges globally, impacting various aspects of daily life, including education. This study examines the effects of the pandemic on stress levels and substance use among Italian medical students. Two independent surveys were conducted: 388 medical students were interviewed before the epidemic, and 222 medical students a year after the COVID-19 epidemic began. Results revealed significant changes in stress levels, with a reduction in mild stress and an increase in sev [...]

548 6527

Open Access Review

Efficacy of Motor Imagery in the Rehabilitation of Stroke Patients: A Scope Review

Danilo Donati ,

Giacomo Farì ,

Federica Giorgi ,

Riccardo Marvulli ,

Francesco Quarta ,

Andrea Bernetti and

Roberto Tedeschi

Received: 29 May 2024; Published: 06 August 2024; doi: 10.21926/obm.neurobiol.2403236

Abstract

This review examines the efficacy of motor imagery (MI) as a supplementary rehabilitation technique for stroke patients. Nine randomized controlled trials (RCTs) were analyzed, highlighting MI's potential to enhance motor recovery, mobility, balance, and psychological well-being. Significant improvements in upper-limb function were observed with combined mental and physical practice, evidenced by notable gains in Fugl-Meyer Assessment (FMA) and Action Research Arm Test (ARAT) scores. MI-based exercise programs impr [...]

732 13213

Open Access Case Report

Exercise and Psychomotor Rehabilitation in a Patient with Alzheimer’s Disease: A Case Report

Catarina F. Martins ,

Jorge Soares and

Maria Paula Mota

Received: 20 March 2024; Published: 01 August 2024; doi: 10.21926/obm.neurobiol.2403235

Abstract

Alzheimer's disease is a neurodegenerative condition that impacts an individual's physical, cognitive, and social well-being, ultimately resulting in a decline in independence and functionality. This case report explores how a program combining multimodal physical exercise and psychomotor rehabilitation can improve outcomes in interventions for Alzheimer's disease patients. This approach can enhance treatment effectiveness and provide researchers and practitioners with additional therapeutic options. The participan [...]

818 9065

Open Access Original Research

COVID-19’s Psychological Threats and Future Career Anxiety among University Students

Nadia A. Abdelmegeed Abdelwahed and

Muhammad Sufyan Ramish

Received: 17 May 2024; Published: 30 July 2024; doi: 10.21926/obm.neurobiol.2403234

Abstract

The COVID-19 pandemic brought different intolerable and uncomfortable situations that ruined the students' academic performance, career opportunities, and social lives through depression, anxiety, fear, uncertainty, and mental illness. In this study, we examined the psychological threats of the COVID-19 among Egypt’s public-sector university students. We employed quantitative methods in this study and used a questionnaire to collect cross-sectional data. The Structural Equation Modeling (SEM) results show that Fear [...]

625 6123

Open Access Original Research

Investigating the Relationship between Lipid Profiles of Stroke Patients at the Time of Admission and Their Outcome

Mohadeseh Rajabpour ,

Alireza Ala ,

Eliyar Sadeghi-Hokmabadi ,

Hasan Amiri ,

Sara Rostamnezhad and

Samad Shams Vahdati

Received: 07 March 2024; Published: 19 July 2024; doi: 10.21926/obm.neurobiol.2403233

Abstract

Hyperlipidemia is one of the critical risk factors for cerebrovascular disease. Many studies have emphasized that controlling the lipid level can decrease the risk of cardiovascular and cerebrovascular events. In this article, we studied all types of lipids in stroke patients and wanted to consider any relation between lipid level in admission and outcome. This retrospective, cross-sectional study was conducted at Imam Reza Research and Training Hospital. It was performed on a sample of 2165 patients who visited th [...]

579 4446

Open Access Review

The Biomolecular Basis of Gut Microbiome on Neurological Diseases

Roberto Anaya-Prado ,

Ana P. Cárdenas-Fregoso ,

Ana M. Reyes-Perez ,

Danielle M. Ortiz-Hernandez ,

Montserrat Quijano-Ortiz ,

Monica V. Delgado-Martinez ,

Ana S. Pelayo-Romo ,

Roberto Anaya-Fernández ,

Michelle M. Anaya-Fernández ,

Consuelo C. Azcona-Ramirez ,

Ivan F. Garcia-Ramirez ,

Miguel A. Guerrero-Palomera ,

Daniel Gonzalez-Martinez ,

Citlalli S. Guerrero-Palomera ,

Karina Paredes-Paredes and

Claudia Garcia-Perez

Received: 23 February 2024; Published: 16 July 2024; doi: 10.21926/obm.neurobiol.2403232

Abstract

The human gastrointestinal (GI) tract harbors many microorganisms, including viruses, protozoa, archaea, fungi, and bacteria. Altogether, these microbes constitute what we know as the gut microbiome (GM). These commensal communities have important implications for human health. They influence physiological processes through different mechanisms, including synthesizing neurotransmitters, regulating enzymatic pathways, and releasing molecules responsible for different signal pathways. The interaction between GM and b [...]

699 7035

Open Access Case Report

Implementation of Cognitive Behavioral Therapy in a Child with Obsessive - Compulsive Disorder: A Case Study

Ioannis Syros and

Xenia Anastassiou-Hadjicharalambous

Received: 19 October 2023; Published: 15 July 2024; doi: 10.21926/obm.neurobiol.2403231

Abstract

Obsessive-Compulsive Disorder (OCD) is a prevalent child and adolescent psychiatric condition characterized by substantial functional impairments. Cognitive Behavioral Therapy (CBT) has emerged as the primary therapeutic approach for managing mild to moderate cases of OCD in children and adolescents. Significant advancements have been made in applying CBT specifically to this age group in the past decade. Exposure and response prevention (ERP) is a core therapeutic technique grounded in the principle that anxiety t [...]

864 7839

Open Access Original Research

Glasgow Coma Scale Scores and Impact of Delirium on Intubated Seizure Patients Treated with Phenytoin and Lacosamide: Retrospective Analysis and Literature Review

Sara Alattar ,

Muhammad Nouman ,

Chidozie Onyiuke ,

Conrad Stasieluk and

Edwin Meresh

Received: 29 November 2023; Published: 05 July 2024; doi: 10.21926/obm.neurobiol.2403230

Abstract

Studies have shown that decrease in time intubated is associated with better prognosis. Delirium is associated with increased duration of mechanical ventilation and Intensive Care Unit (ICU) length of stay. However, there is limited report on delirium in intubated seizure patients. As per report, low Glasgow Coma Scale (GCS) increased the risk of delirium and thus increasing ICU length of stay. Information on delirium and outcome in intubated seizure patients receiving lacosamide versus phenytoin is limited. Our re [...]

900 8621

Open Access Original Research

Alpha/Theta Neurofeedback Rehabilitation for Improving Attention and Working Memory in Female Students with Learning Disabilities

Roghieh Nooripour ,

Maryam Ghanbari Viki ,

Nikzad Ghanbari ,

Fardin Farmani and

Farinaz Emadi

Received: 07 April 2024; Published: 01 July 2024; doi: 10.21926/obm.neurobiol.2403229

Abstract

Learning disabilities (LDs) encompass a range of cognitive challenges that can significantly influence students' educational experiences and overall academic performance. This study aimed to investigate the effects of alpha/theta neurofeedback rehabilitation on attention and working memory in female students with learning disabilities. This study employed a quasi-experimental design with pre-tests, post-tests, and a two-month follow-up and included a control group. Convenience sampling was used to select 40 fem [...]

1518 18986

Open Access Original Research

A Technology-Aided Program to Help People with Profound Intellectual and Multiple Disabilities Access Preferred Stimulation and Exercise Motor Responses and Visual Orientation

Giulio E. Lancioni ,

Gloria Alberti ,

Chiara Filippini ,

Nirbhay N. Singh ,

Mark F. O'Reilly and

Jeff Sigafoos

Received: 14 March 2024; Published: 28 June 2024; doi: 10.21926/obm.neurobiol.2402228

Abstract

People with profound intellectual and multiple disabilities (PIMD) are generally isolated, with a high risk of reduced stimulation input and physical inactivity. One of the strategies available to mitigate this situation relies on using technology-aided programs delivering stimulation contingent on people’s basic responses/activation. The two studies reported here were intended to extend the evidence available in this area. Specifically, Study I assessed whether a technology-aided program, which enabled participant [...]

678 4577

Open Access Original Research

Is Wheelchair Basketball a Symmetric or Asymmetric Sport?

Giacomo Farì ,

Enrica Chiaia Noya ,

Laura Dell'Anna ,

Vincenzo Ricci ,

Francesco Quarta ,

Laura Masiero ,

Andrea Bernetti ,

Marisa Megna and

Maurizio Ranieri

Received: 16 January 2024; Published: 25 June 2024; doi: 10.21926/obm.neurobiol.2402227

Abstract

Wheelchair basketball (WB) is a health and inclusion opportunity for people with disabilities. In the scientific literature, no evidence defines WB as a symmetrical or asymmetrical sport; however, it would be helpful to deepen this aspect because it could improve the quality of training programs and consequently speed up WB performance. In WB, the biomechanical role of the shoulders is crucial. Therefore, the symmetry index and the activation of the bilateral supraspinatus and biceps brachii muscles were investigat [...]

959 6924

Open Access Review

The Effectiveness of Using Progressive Muscle Relaxation Techniques on Quality of Life, Stress, And Anxiety Among Acute Myocardial Infarction: A Systematic Review

Ala'a A. AI-yyan ,

Ayat A. ELayan and

Mohammad Saleh

Received: 28 February 2024; Published: 16 June 2024; doi: 10.21926/obm.neurobiol.2402226

Abstract

The progressive muscle relaxation technique (PMRT) is an active method that is defined as a technique through which individuals gradually cause a feeling of quietness and coolness by actively contracting and loosening specific muscle groups. The purpose of this study was to review the effectiveness of using progressive muscle relaxation techniques on quality of life, stress, and anxiety levels among Acute Myocardial Infarction patients. A systematic review of randomized controlled trials (2013-2023). Databases of P [...]

1607 14292

Open Access Review

Enhancing University Students’ Mental Health under Artificial Intelligence: Principles of Behaviour Therapy

Mubashir Zafar

Received: 13 March 2024; Published: 24 May 2024; doi: 10.21926/obm.neurobiol.2402225

Abstract

The increasing prevalence of mental health issues among university students has become a growing concern globally. This review explores the potential of Artificial Intelligence (AI) integrated with principles of behaviour therapy to address mental health challenges among university students. The paper examines how AI technologies, including chatbots, virtual reality, and machine learning algorithms, can be harnessed to provide accessible, personalized, and effective mental health interventions. Furthermore, it disc [...]

1235 14732

Open Access Original Research

Assessing the Factor Structure and Construct Validity of the Beck Depression Inventory (BDI-II) in a Korean Preschool Teacher Sample

Yang Eun Kim and

Boram Lee

Received: 07 March 2024; Published: 21 May 2024; doi: 10.21926/obm.neurobiol.2402224

Abstract

Preschool teachers are at high risk of depression. Therefore, emphasis should be placed on evaluating a valid and reliable instrument to measure depressive symptomatology for this population. One such promising instrument is the Beck Depression Inventory (BDI-II), a 21-item self-report measure designed to assess the presence and severity of depression. Although the tool’s psychometric properties have been analyzed in different samples, they have not been validated with a Korean preschool teacher sample. Hence, this [...]

1167 13034

Open Access Review

Red Algae Compounds: Potential Neuroprotective Agents for Neurodegenerative Disorders

Leonel Pereira and

Ana Valado

Received: 06 March 2024; Published: 10 May 2024; doi: 10.21926/obm.neurobiol.2402223

Abstract

This review explores the potential of compounds derived from red algae (Rhodophyta) as promising neuroprotective agents for treating neurodegenerative disorders. Red algae, abundant in marine environments, contain bioactive compounds with diverse chemical structures and functionalities. Sulfated polysaccharides, primarily agar and carrageenans, stand out as the predominant and widely utilized compounds derived from red algae. Additionally, red algae harbor a spectrum of potential molecules such as essential fatty a [...]

1584 12521

Open Access Original Research

Determining the Contribution of Physical Activity Constructs in Developing Intention to Exercise among Entrepreneurs

Nadia A. Abdelmegeed Abdelwahed

Received: 08 January 2024; Published: 06 May 2024; doi: 10.21926/obm.neurobiol.2402222

Abstract

In the present era, a healthy life is a challenge for everyone. Therefore, diverting individuals' minds towards physical activity and exercise is necessary for the day. This paper proposes to inspect the impact of physical activity on the development of intention to exercise (ITE) among entrepreneurs. The quantitative study collected data from 383 Egyptian entrepreneurs through a survey questionnaire. Most respondents were males (n = 257 or 67.10%) against females (n = 126 or 32.90%). The range of age of the respon [...]

1059 5755

Open Access Original Research

Mental Health of Teachers during the First Wave of COVID-19 in Daegu, Korea: Challenges in Reopening Schools

Jihyun Cho ,

Hojun Lee ,

Sang Hee Park ,

Myoung Haw Kim and

Seunghee Won

Received: 25 February 2024; Published: 06 May 2024; doi: 10.21926/obm.neurobiol.2402221

Abstract

This study conducted an in-depth analysis of the psychological states of teachers during the first outbreak of coronavirus disease 2019 (COVID-19) using data on school mental health projects related to COVID-19 in Daegu from May to June 2020. The participants comprised 811 (34.9%) male and 1,511 (65.1%) female teachers in 1,041 (44.8%) middle and 1,281 (55.2%) high schools. After schools reopened, the most common causes of unbearable stress were unusual experiences, fear of infection, and negative emotions. Moreove [...]

895 6371

Open Access Original Research

Understanding Mental Health Needs and Predictors of Anxiety in Emirati Female Students in Higher Education

Jigar Jogia ,

Fatma Anwahi ,

Shaikha Aburehaima ,

Alia Sharif and

Veena Kumari

Received: 09 November 2023; Published: 28 April 2024; doi: 10.21926/obm.neurobiol.2402220

Abstract

The prevalence rates of depression, anxiety, and stress range between 5% to 70% globally. Many students experience these mental health conditions as they go through transitional periods in life, such as starting higher education. This study aimed to explore mental health concerns, specifically depression, anxiety, stress, and quality of sleep, in Emirati female university students, a topic that has been understudied in the Middle East. We used the Depression, Anxiety, and Stress Scales (DASS-21) and the Pittsburgh [...]

920 9052

Open Access Original Research

The Impact of Physical Activity on Brain Neuroplasticity, Cognitive Functions and Motor Skills

Liana Spytska

Received: 20 December 2023; Published: 25 April 2024; doi: 10.21926/obm.neurobiol.2402219

Abstract

The research aims to study the mechanisms and factors contributing to brain neuroplasticity. To achieve this goal, the following methods were used: analysis and synthesis, hermeneutic method, psychological testing, and comparative and generalization methods. The research results revealed the nature of the concept of brain neuroplasticity and types of neuroplasticity, analyzed the process of redistribution of brain functions, determined the role of compensatory plasticity, revealed methods of studying brain neuropla [...]

1359 25212

Open Access Original Research

Oleuropein can Protect the Brain Against Deleterious Effects of Bile Duct Ligation in Male Mice

Faezeh Kouhakan ,

Sepideh Ganjalikhan ,

Alireza Sarhadizadeh ,

Khadijeh Esmaeilpour ,

Khatereh Akbari ,

Leila Jafaripour and

Majid Asadi-Shekaari

Received: 26 December 2023; Published: 23 April 2024; doi: 10.21926/obm.neurobiol.2402218

Abstract

Oleuropein (OP) is a phenolic compound in olives. OP possesses potent antioxidant activity and an extensive spectrum of other pharmacological properties, including antiviral, anti-inflammatory, and antimicrobial activities. This study investigated the effects of OP on neural injuries caused by bile duct ligation (BDL) in male mice. The mice were randomly allocated to three groups: sham, BDL, and BDL + OP. Neurobehavioral tests histological and biochemical evaluations were accomplished to assess cerebral damage. The [...]

887 4381

Open Access Original Research

Compassionate Love for a Romantic Partner among Brazilian College Students

Joana Neto and

Félix Neto

Received: 08 February 2024; Published: 12 April 2024; doi: 10.21926/obm.neurobiol.2402217

Abstract

Compassionate love (CL) is a recent subject of close relationships. CL is focused on enlarging beneficence to another. The present study approaches the test of the psychometric characteristics of the shortened form of the Compassionate Love Scale for a partner (CLS-P-SF) for Brazilian college students and its relationships with background and well-being variables. The sample included 217 young adults, 46.1% women and 53.9% men. Confirmatory factor analysis revealed that the single latent factor of the CLS-P-SF is g [...]

1116 5561

Open Access Original Research

Attitudes and Motivations Towards Implantation of Intention Towards Exercise among Entrepreneurs: A Brain Freshness Activity

Mohammed A. AI Doghan ,

Nadia A. Abdelmegeed Abdelwahed and

Bahadur Ali Soomro

Received: 19 October 2023; Published: 10 April 2024; doi: 10.21926/obm.neurobiol.2402216

Abstract

In the contemporary landscape, developing individuals' attitudes, motivations, and intentions toward exercise and physical activities emerges as an imperative cornerstone for fostering a healthy and thriving lifestyle. The present study examines the effect of the theory of the planned behavior (TPB) constructs on exercise motivation (MT) and intention towards exercise (ITWE) among Egyptian entrepreneurs. The study employed a quantitative approach and collected cross-sectional responses from entrepreneurs throug [...]

835 4815

Open Access Short Review

Postoperative Cognitive Dysfunction and Virtual Reality for Cognitive Rehabilitation in Cardiac Surgery Patients: A Short Review

Irina V. Tarasova and

Olga A. Trubnikova

Received: 02 November 2023; Published: 19 March 2024; doi: 10.21926/obm.neurobiol.2401215

Abstract

Postoperative cognitive dysfunction (POCD) has been observed as a complication after cardiac surgery consistently. The ineffectiveness of current treatments for POCD is causing a search for non-invasive alternatives. The present review aims to consolidate the current understanding of how VR methods effectively facilitate the recovery of cognitive functioning in cardiac surgery patients. To obtain information about the effects of VR technology on cognitive functions, we investigated the PubMed, Scopus, and Web of Sc [...]

1045 5319

Open Access Case Report

Management of Posttraumatic Cerebrospinal Fluid Leak with Secondary Diffuse Pneumocephalus Complicated by Meningitis and Communicating Hydrocephalus – Illustrative Case Report

Sintija Strautmane ,

Arturs Balodis ,

Klavs Smidrovskis and

Kaspars Auslands

Received: 10 January 2024; Published: 13 March 2024; doi: 10.21926/obm.neurobiol.2401214

Abstract

Rhinorrhea is a possible complication after different types of traumatic brain injury or neurosurgical procedures, such as skull base operations. Pneumocephalus is a rarely noted complication after severe traumatic brain injury, and it may be accompanied by meningitis and ventriculitis, especially when treatment has been delayed. Treatment of these entities includes conservative and surgical approaches. Pneumocephalus may result in neurologic disturbances threatening a life. Therefore, active patient management wit [...]

807 5055

Open Access Correction

Correction: Tse et al. How COVID-19 Ceases All Older Adult Services & the Way Out for Community-Dwelling Older Adults with Chronic Pain. OBM Neurobiology 2023; 7: 183

Mimi Mun Yee Tse ,

Shamay Sheung Mei Ng ,

Vivian Lou ,

Raymond SK Lo ,

Daphne Sze Ki Cheung ,

Paul H Lee ,

Shuk Kwan Tang ,

Siu Hang Leung and

Percy Poo-See Tse

Received: 11 March 2024; Published: 12 March 2024; doi: 10.21926/obm.neurobiol.2401213

Abstract

CorrectionCorrection: Tse et al. How COVID-19 Ceases All Older Adult Services & the Way Out for Community-Dwelling Older Adults with Chronic Pain. OBM Neurobiology 2023; 7: 183Mimi Mun Yee Tse 1, *, Shamay Sheung Mei Ng 2, Vivian Lou 3, Raymond SK Lo 4, Daphne Sze Ki Cheung 5, Paul H Lee 6, Shuk Kwan Tang 7, Siu Hang Leung 1, Percy Poo-See Tse 1* Correspondence: Mimi Mun Yee Tse; E-Mail: mmytse@hkmu.edu.hkAcademic Editors: Ines Testoni, Adriano Zamperini and Lorenza PalazzoSpecial Issue: How COVID-19 Changed Indi [...]

789 4272

Open Access Original Research

Resilience in Adversity: COVID-19 Pandemic Challenges in Diminishing Entrepreneurial Intentions and Business Startups

Nadia A. Abdelmegeed Abdelwahed ,

Mohammed A. Al Doghan and

Bahadur Ali Soomro

Received: 13 November 2023; Published: 11 March 2024; doi: 10.21926/obm.neurobiol.2401212

Abstract

In this study, the researchers explore the effects of COVID-19-related challenges, such as fear and anxiety about COVID-19, the uncertainty of COVID-19, and the recognition of business opportunities for entrepreneurial intentions and business startups. This study used quantitative methods and based their findings on 278 usable samples collected from Egyptian entrepreneurs. Employing the Structural Equation Model (SEM) through SmartPLS4 shows that fear and anxiety arising from the COVID-19 pandemic harm entrepreneur [...]

1043 6576

Open Access Review

The Role of Cognition in Balance Control

Nazrien M.D Nazrien ,

Novitri ,

Tertianto Prabowo and

Farida Arisanti

Received: 14 September 2023; Published: 17 February 2024; doi: 10.21926/obm.neurobiol.2401211

Abstract

Balance is the ability to move and/or preserve a particular position while not falling under external force. Human balance is a complex process of integration and coordination of the sensory, motor, and biomechanical components, which is influenced by intrinsic and exogenous factors. One inherent factor that is hypothesized to have an impact on balance is cognition. However, studies about cognition's role in balance control are still limited, and study literature is needed to gain a better understanding. Cognition [...]

1985 13778

Open Access Editorial

Pain and Neurobiology

Varrassi Giustino

Received: 01 February 2024; Published: 02 February 2024; doi: 10.21926/obm.neurobiol.2401210

Abstract

Neurobiology is an expansive field of studies encompassing the nervous system's anatomical and physiological aspects [1]. This complex framework's deep study and understanding have facilitated a more intricate comprehension of the interconnections among various nervous system components implicated in pain perception, transmission, modulation, and adaptation.

820 4969

Open Access Review

The Association between Uric Acid Level and Ischemic Stroke

Yang Xu ,

Eng Hwa Wong ,

Rusli Bin Nordin ,

Abdul Kareem Meera Mohaideen ,

Benjamin Samraj Prakash Earnest and

Yin How Wong

Received: 11 July 2023; Published: 16 January 2024; doi: 10.21926/obm.neurobiol.2401209

Abstract

Stroke is the second and third leading cause of death and disability, respectively, all over the world. It seriously affects patients' lives and brings huge burdens to their families. Ischemic stroke accounts for most of the stroke cases. In the absence of any effective treatment, prevention measures through controlling the risk factors for ischemic stroke become crucial. While uric acid has been reported as an essential risk factor for ischemic stroke, researchers hold inconsistent views regarding the specific ass [...]

1182 7507

Open Access Review

Scope of Nanomaterials in Treating Neurological Disorders

Aaryan Gupta ,

Arpita Roy ,

Kirtanjot Kaur ,

Sarvesh Rustagi ,

Sumira Malik and

Soumya Pandit

Received: 08 November 2023; Published: 11 January 2024; doi: 10.21926/obm.neurobiol.2401208

Abstract

In the last decade, development in nanotechnology has been used intensively. By studying nanotechnology and nanomaterials, we can generate excellent responses in healthcare related to neurological disorders. It also includes easy diagnosis of diseases in their early stages, delivery of genes, and many more. Neurological disorders are one of the most sensitive topics. Therefore, nanomaterials promise to treat neurological disorders as they are highly efficient. Nanomaterials will significantly expand our knowledge o [...]

1879 10505

Open Access Original Research

Neuroprotective Effects and Cognitive Enhancement of Allomargaritarine in 5xFAD Alzheimer's Disease Mice Model

Yulia Aleksandrova ,

Alexey Semakov ,

Dmitry Tsypyshev ,

Kirill Chaprov ,

Sergey Klochkov and

Margarita Neganova

Received: 23 August 2023; Published: 09 January 2024; doi: 10.21926/obm.neurobiol.2401207

Abstract

Here, we report the results of an investigation of the neuroprotective effects of securinine with tryptamine conjugate-allomargaritarine (2b), previously selected as the leading compound among a wide range of natural derivatives. 2b was synthesized from securinine using various Lewis acids as catalysts. In addition to the antioxidant and cytoprotective properties previously shown for 2b, in this work, in vitro analysis of the biological activity of the compound demonstrated that this conjugate is also able to influ [...]

1246 7737

Open Access Original Research

Patient-Reported Outcome Measures (PROMs) in Neurology for Web 3.0 and mHealth: A Conceptual Framework

Talha Nazir ,

Muhammad Umair ,

Muhammad Mushhood Ur Rehman ,

Reeda Saeed ,

Osama O Zaidat and

Junaid S. Kalia

Received: 02 June 2023; Published: 09 January 2024; doi: 10.21926/obm.neurobiol.2401206

Abstract

According to 2019 WHO data, neurological conditions contribute to 1503.39 disability-adjusted life years (DALYs) per 100,000 population. Approximately 57% of office-based physicians use EHR systems and the natural place to incorporate standardized ePRO is into EHR. However, implementing patient-reported outcomes (PROs) for neurological conditions is challenging because many patients are elderly, have comorbidities, and experience cognitive impairment. As healthcare digitization increases, we propose a framework for [...]

1061 6593

Open Access Original Research

The Impact of Psychological Stress on Personal Income, Physical Health and Entrepreneurial Intentions among Entrepreneurs

Nadia A. Abdelmegeed Abdelwahed

Received: 19 September 2023; Published: 04 January 2024; doi: 10.21926/obm.neurobiol.2401205

Abstract

Entrepreneurial intention plays a pivotal role within entrepreneurship ecosystems, acting as a catalyst for economic growth and innovation by inspiring individuals to embrace entrepreneurship as a viable career pursuit. The present research delves into the intricate dynamics between stress, entrepreneurial intention, personal income, and physical health within Egypt's entrepreneurial landscape. Grounded in a quantitative analysis of 286 valid samples and utilizing SmartPLS 4, this study unveils compelling insights. [...]

1632 9743

Open Access Editorial

Acknowledgement to Reviewers of OBM Neurobiology in 2023

OBM Neurobiology Editorial Office

Received: 03 January 2024; Published: 02 January 2024; doi: 10.21926/obm.neurobiol.2401204

Abstract

The editors of OBM Neurobiology would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2023. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal’s editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers can download a certificate of recognition directly from our submission system. Additionally, reviewers can sign up to the [...]

718 3787

Open Access Original Research

Interactive Technology to Help People with Multiple Disabilities Practice Relevant Physical Responses within an Occupational Task

Giulio E. Lancioni ,

Gloria Alberti ,

Chiara Filippini ,

Alessandra Fiore ,

Clarissa Simonetti ,

Nirbhay N. Singh ,

Mark F. O'Reilly and

Jeff Sigafoos

Received: 09 October 2023; Published: 02 January 2024; doi: 10.21926/obm.neurobiol.2401203

Abstract

This study adapted a new interactive technology system to help six participants with intellectual disability and visual and motor impairments to exercise relevant physical responses as part of an occupational task. The task was to place objects into different containers from a sitting position. The responses, which changed across sessions, consisted of the participants (a) stretching the left arm and shoulder to place objects in a container located to their left, (b) stretching the right arm and shoulder to place o [...]

996 5698

Open Access Concept Paper

An Overview of Recent Technology-Aided Intervention Strategies to Help People with Intellectual and Multiple Disabilities Meet Relevant Rehabilitation Goals

Giulio E. Lancioni ,

Nirbhay N. Singh ,

Mark F. O'Reilly ,

Jeff Sigafoos ,

Gloria Alberti and

Marta Olivetti Belardinelli

Received: 09 September 2023; Published: 15 December 2023; doi: 10.21926/obm.neurobiol.2304202

Abstract

The paper presents an overview of recent studies assessing technology-aided strategies aimed at helping people with intellectual and multiple disabilities reach relevant rehabilitation goals. The 16 studies included in the paper addressed four specific rehabilitation goals, that is, (a) performance of functional activities, (b) access to leisure and communication and performance of functional activities, (c) increase of adaptive responses and decrease of problem behavior or inadequate posture, and (d) increase of a [...]

1182 6598

Open Access Short Communication

Targeted MRI (tMRI) of Small Increases in the T₁ of Normal Appearing White Matter in Mild Traumatic Brain Injury (mTBI) Using a Divided Subtracted Inversion Recovery (dSIR) Sequence

Gil Newburn ,

Joshua P McGeown ,

Eryn E Kwon ,

Maryam Tayebi ,

Paul Condron ,

Taylor Emsden ,

Samantha J Holdsworth ,

Daniel M Cornfeld and

Graeme M Bydder

Received: 30 June 2023; Published: 14 December 2023; doi: 10.21926/obm.neurobiol.2304201

Abstract

In modelling studies targeted MRI (tMRI) of small increases in the T1 of tissues using divided Subtracted Inversion Recovery (dSIR) sequences show ten or more times the contrast seen with conventional IR sequences. This may be particularly useful in imaging normal appearing white matter where there may be small changes in T1 and/or T2 in disease but these changes may be insufficient to produce useful contrast with conventional T2-weighted spin echo (T2-wSE) and T2-FLuid Attenuated Inversion Recovery (T2-FLAIR) sequ [...]

1094 7581

Open Access Original Research

Effects of Ficus Platyphylla-Induced Hypothermia on Long-term Functional Recovery after Ischaemic Stroke

Axel Becker ,

Martin Helmuth and

Ben A. Chindo

Received: 19 October 2023; Published: 05 December 2023; doi: 10.21926/obm.neurobiol.2304200

Abstract

A stroke is a cerebrovascular disease that results from a blockage in the blood supply to part of the brain or a burst blood vessel in the brain. It is the second leading cause of death worldwide, with an annual mortality rate of about 5.5 million. Antithrombotic therapies have failed to provide a cure for this debilitating cerebrovascular disorder, and hypothermia is gaining interest as a novel strategy for the management of stroke. In this study, we evaluated the effects of Ficus platyphylla-induced hypothermia o [...]

851 5670

Open Access Original Research

Association between Posttraumatic Stress Symptoms and Resilience in Frontline Healthcare Workers during the COVID-19 Pandemic in Vietnam

Linh Nguyen Thi Phuong ,

Khoa Le Duc ,

Khanh Do nam ,

Hao Tran Thi ,

Huong Dang Thi ,

Giang Le Minh and

Van Hoang Thi Hai

Received: 11 October 2023; Published: 30 November 2023; doi: 10.21926/obm.neurobiol.2304199

Abstract

The COVID-19 pandemic has placed a considerable burden on frontline healthcare workers (HCWs), thus increasing their vulnerability to developing posttraumatic stress disorder (PTSD). Our study aimed to examine the relationship between possible PTSD symptoms and resilience and identify associated factors with possible PTSD symptoms among Vietnamese frontline HCWs during the COVID-19 pandemic in 2021. We conducted a cross-sectional study across medical facilities at three administrative levels: provincial, district, [...]

1038 6775

Open Access Review

Understanding the Potentiality of Artificial Intelligence in Psychological Disorders Detection and Diagnostics

Krishanu Aich ,

Sukrit Kashyap ,

Konika Tyagi ,

Ishika Verma ,

Abhimanyu Chauhan and

Chakresh Kumar Jain

Received: 09 April 2022; Published: 29 November 2023; doi: 10.21926/obm.neurobiol.2304198

Abstract

Today, the advancement of assessment, forecasting, and therapy or medical attention for psychological healthcare is already using artificial intelligence (AI) technology, particularly machine learning, due to the introduction of digital tools to treat mental health conditions. In mental health treatment, the present and the future of artificial intelligence technologies hold both enormous promises and potential dangers. With the current global scenario, psychological disorders like clinical depression, general anxi [...]

1697 9636

Open Access Original Research

Anxiety, Stress and Depression as the Notorious Barriers to Achieving a Massive Performance among Egyptian Construction Site Workers

Nadia A. Abdelmegeed Abdelwahed ,

Mohammed A. Al Doghan and

Bahadur Ali Soomro

Received: 25 August 2023; Published: 24 November 2023; doi: 10.21926/obm.neurobiol.2304197

Abstract

In today's corporate landscape, optimizing performance has emerged as a formidable challenge for organizations, often hindered by formidable barriers and psychological factors. This study explores the role of anxiety, stress, and depression in attaining performance among Egyptian construction site workers. The quantitative analysis utilizes cross-sectional data collected from workers working at different construction sites in Egypt. The study concludes with findings from 298 valid cases. Leveraging the structur [...]

771 6891

Open Access Research Article

Validation of the Insomnia Severity Index among University Students in Korea

Boram Lee and

Yang Eun Kim

Received: 12 July 2023; Published: 21 November 2023; doi: 10.21926/obm.neurobiol.2304196

Abstract

Insomnia is the most common sleep complaint in clinical practice, affecting both the physical and mental health of patients as well as many aspects of their life quality. Young adults, especially university students, are prone to a high prevalence of poor sleep quality or insomnia. Accurate assessment of insomnia severity among university students has become an important issue. One promising screening tool to identify clinically significant insomnia in the campus setting is the Insomnia Severity Index (ISI), a seve [...]

1366 11611

Open Access Original Research

Assessment of a Person's Social Success Through the Characteristics of Interpersonal Relationships in A Virtual Environment

Aleksey Shevcov ,

Pavel Ustin ,

Leonid Popov ,

Fail Gafarov and

Galim Vakhitov

Received: 30 April 2023; Published: 13 November 2023; doi: 10.21926/obm.neurobiol.2304195

Abstract

The sudden spread of the COVID-19 pandemic has convincingly proved the role of social networks in human life activity as an actor of interpersonal relations. The need for isolation and the limitation of face-to-face communication between people has significantly transformed the system of interpersonal connections through an extensive increase in social contacts in the virtual environment and the growing importance of online social services. In the study, we addressed the problem of diagnosing the indicator of socia [...]

815 6034

Open Access Review

Rehabilitation of Chronic Pain in Post-Critical Care Patients. A Narrative Review

Evanthia Asimakopoulou and

Periklis Zavridis

Received: 11 April 2023; Published: 08 November 2023; doi: 10.21926/obm.neurobiol.2304194

Abstract

Chronic pain in post-critical care patients is a multifaceted issue with profound implications for patient well-being and quality of life. This review aims to address the rehabilitation of patients who suffer from chronic pain following discharge from the intensive care unit (ICU). Despite growing awareness of the prevalence and impact of this condition, significant gaps in knowledge persist regarding the optimal rehabilitation strategies for these patients. To conduct this study, an extensive literature search was [...]

1084 7985

Open Access Review

Building Resilience in Students: Managed and Minimised Stress in Students

Gulzhaina K. Kassymova ,

Mariam R. Arpentieva ,

Bakhyt D. Zhigitbekova ,

Hans Schachl ,

Aigerim N. Kosherbayeva ,

Kundyz Zh. Aganina ,

Farid R. Vafazov ,

Petr V. Menshikov ,

Marina G. Golubchikova and

Andrey I. Korobchenko

Received: 07 March 2023; Published: 07 November 2023; doi: 10.21926/obm.neurobiol.2304193

Abstract

Stressful events in students' and teachers' personal, academic, and professional lives are widespread. The paper discusses many effective methods and techniques for correcting and preventing stress that are simple to learn and practice. They give good results in working with children, adolescents, and youths in training and education. Some practices are more complex and require more attention and effort to understand and master them, but they also have broader capabilities in various situations. Therefore, training [...]

2151 15932

Open Access Short Communication

Low-Frequency Oscillations for Nonlocal Neuronal Coupling in Shared Intentionality Before and After Birth: Toward the Origin of Perception

Igor Val Danilov

Received: 09 May 2023; Published: 02 November 2023; doi: 10.21926/obm.neurobiol.2304192

Abstract

The theoretical study observes literature to understand whether or not low-frequency oscillations can simultaneously alter the excitability of neurons from peripheral nervous subsystems in different individuals to provide Shared Intentionality in recipients (e.g., fetuses and newborns) and what are the attributes of ecological context for Shared Intentionality. To grasp the perception of objects during environmental learning at the onset of cognition, a fetus needs exogenous factors that could stimulate her nervous [...]

1139 16299

Open Access Review

Technological Resources for Early Intervention in Cases of Dyscalculia: A Deductive-Inductive Categorization

Estefanía Espina ,

José M. Marbán and

Ana I. Maroto

Received: 29 May 2023; Published: 23 October 2023; doi: 10.21926/obm.neurobiol.2304191

Abstract

Dyscalculia is a math learning disability that significantly interferes with students' academic performance and math-related aspects of their daily lives. Early diagnosis and the design of intervention programs adapted to the needs of each case are essential. In this sense, multiple technological resources are created to address both issues. Still, it is difficult to identify which characteristics they share and which are more relevant regarding didactic suitability. Given this situation, this research proposes cat [...]

1765 14856

Open Access Research Article

Factor Structure of ASD Symptoms in Russian 3-4-Year-Olds

Andrey Nasledov ,

Sergey Miroshnikov ,

Liubov Tkacheva and

Sergey Fedorov

Received: 08 June 2023; Published: 19 October 2023; doi: 10.21926/obm.neurobiol.2304190

Abstract

The study aims to reveal autism vectors that are inherent in 3-4-year-olds with ASD. Three hundred eighty-three children with ASD took part in the research. An online questionnaire developed earlier by our research group was used. In the first stage, with the repeated use of exploratory factor analysis, the task of identifying the simplest factor structure was solved. As a result, a 7-factor system was obtained, including from 9 to 14 items in each factor (78 items in total): 1) "Persistence on sameness" (Sam); 2) [...]

1185 7006

Open Access Technical Note

A New Computer-Aided Method for Assessing Children's Cognition in Bioengineering Systems for Diagnosing Developmental Delay

Igor Val Danilov ,

Araksia Svajyan and

Sandra Mihailova

Received: 05 April 2023; Published: 18 October 2023; doi: 10.21926/obm.neurobiol.2304189

Abstract

This pilot study (n = 19) examines fidelity rates of the new computer-aided method of diagnosing cognitive development delay in 3-to-6-year-old children. The small-scale research repeats the methodological components of the previous two studies, only changing the data collection process by introducing the baseline value (BV). Experimental data show a significant increase of 9.4 times in the shared intentionality magnitude in neurodivergent children. The results support the hypothesis that the bioengineering system [...]

910 9050

Open Access Case Report

Neuroleptic Malignant Syndrome in a Patient with Autism Spectrum Disorder: Case Report

Stefan Klek ,

Jonathan Newgren ,

Philip Burns ,

Angelika Kwak ,

Eric Casinelli ,

Tony Tu ,

Theodote K. Pontikes and

Edwin Meresh

Received: 10 May 2023; Published: 13 October 2023; doi: 10.21926/obm.neurobiol.2304188

Abstract

Neuroleptic Malignant Syndrome (NMS) and Malignant Catatonia (MC) are conditions with significant overlap and are classically characterized by autonomic dysfunction, rigidity, bradyreflexia, posturing, lead-pipe rigidity in the former and waxy flexibility in the latter, stereotyping, an increase in creatinine kinase, and/or leukocytosis. Onset after inciting factor ranges from days to weeks, as does resolution with appropriate treatment. The overlap in symptomatology with Autism spectrum disorder (ASD) presents a f [...]

958 8393

Open Access Short Communication

Rethinking Driving Assessment: A Hypothesis-Driven Proposal for Cognitive Evaluation

Jose L. Tapia and

Jon Andoni Duñabeitia

Received: 31 March 2023; Published: 10 October 2023; doi: 10.21926/obm.neurobiol.2304187

Abstract

Driving is a critical aspect of personal mobility and autonomy, but ensuring road safety requires a comprehensive evaluation of driving abilities beyond self-reported behaviors and practical skills. This article emphasizes the importance of cognitive assessment in determining fitness to drive and explores the potential benefits of using digital tools for such evaluations to enhance road safety. Implementing these digital tools does come with challenges, such as unfamiliarity with digital cognitive reviews for some [...]

1272 8405

Open Access Original Research

Evaluation of Bioactive Compounds Obtained from Ginkgo Biloba Against Crystal Structure of Myelin Oligodendrocyte Glycoprotein (MOG)

Aaryan Gupta ,

Arpita Roy ,

Soumya Pandit ,

Neha Pandey and

Sarvesh Rustagi

Received: 07 July 2023; Published: 09 October 2023; doi: 10.21926/obm.neurobiol.2304186

Abstract

Multiple Sclerosis (MS) spreads rapidly across the globe, causing almost 2.8 million cases worldwide. Many drugs and inhibitors, such as dronabinol and nabilone, have been used to treat MS, but there is no effective treatment for MS till now as these medications can cause severe side effects. So, we tested different compounds from Ginkgo biloba to inhibit the symptoms caused by MS as an herbal treatment. We targeted the Crystal structure of Myelin Oligodendrocyte Glycoprotein as it has shown some excellent results [...]

1106 8002

Open Access Short Communication

Shared Intentionality Modulation at the Cell Level: Low-Frequency Oscillations for Temporal Coordination in Bioengineering Systems

Igor Val Danilov

Received: 20 June 2023; Published: 05 October 2023; doi: 10.21926/obm.neurobiol.2304185

Abstract

The theoretical article aims to develop knowledge about the modulation of shared intentionality at the cellular level. A hypothesis about the neurobiological processes during shared intentionality argues that this pre-perceptual communication occurs through nonlocal neuronal coupling in an ecosystem that can be described as the mother-fetus communication model. The current theoretical study analyses literature to discuss recent findings on the effect of oscillations on neuronal temporal coordination to verify wheth [...]

1297 31068

Open Access Research Article

Demographic Factors, COVID-19-related Factors, and PTSD Symptom Clusters: Exploring Associations and Implications for Mental Health

Anita Padmanabhanunni and

Tyrone Pretorius

Received: 26 April 2023; Published: 25 September 2023; doi: 10.21926/obm.neurobiol.2303184

Abstract

The COVID-19 pandemic was characterized as a continuous traumatic stressor and associated with high levels of posttraumatic stress disorder (PTSD). This study examines the associations between demographic factors, COVID-19-related factors (fear of COVID-19 and perceived stress), and PTSD, as well as the associations between PTSD and indices of mental health. The participants in the study were university students (n = 322) who completed the PTSD Checklist for the Diagnostic and Statistical Manual-5 (DSM-5), the Fear [...]

785 5097

Open Access Research Article

How COVID-19 Ceases All Older Adult Services & the Way Out for Community-Dwelling Older Adults with Chronic Pain

Mimi Mun Yee Tse ,

Shamay Sheung Mei Ng ,

Vivian Lou ,

Raymond SK Lo ,

Daphne Sze Ki Cheung ,

Paul H Lee ,

Shuk Kwan Tang ,

Siu Hang Leung and

Percy Poo-See Tse

Received: 02 August 2023; Published: 15 September 2023; doi: 10.21926/obm.neurobiol.2303183

Abstract

The COVID-19 pandemic started at the beginning of 2020. It significantly impacted the older adults in Hong Kong, with most of the community centers and elderly centers being closed down under various restrictive measures. Thus, community-based health promotion activities were temporarily paused, which decreased older adults’ health-promoting behaviors and motivation to stay active. This research aimed to improve the quality of life and the health of older adults with chronic pain through the pain management program [...]

983 6105

Open Access Original Research

Affinity for Technology Relates to Group Cohesion for New, But Not Existing, Groups

Marlena R. Fraune ,

Danielle Langlois ,

Harrison Preusse ,

Jennifer M. Rheman ,

Katrina Ling and

Katherine M. Tsui

Received: 14 April 2023; Published: 07 September 2023; doi: 10.21926/obm.neurobiol.2303182

Abstract

During the 2020 COVID-19 pandemic, governments around the world mandated shutdowns and social distancing, limiting how much people could see other people outside of their household. Because of this, people had negative mental health outcomes, and many people turned to technology to maintain connections and create new ones. In this paper, we examine the relationship between technology, mental health, and group cohesion with existing groups (N = 202) and new groups (N = 74). We surveyed U.S. participants in June 2020 [...]

852 5923

Open Access Review

Classical and Non-Classical Neural Communications

William Winlow ,

Rouholah Fatemi and

Andrew S. Johnson

Received: 13 April 2023; Published: 27 August 2023; doi: 10.21926/obm.neurobiol.2303181

Abstract

This review was constructed to show how the connectome has evolved in motor command systems from simple command elements to complex systems of neurons utilizing parallel distributed processing and the possibility of quantum entanglement between groups of neurons. Scientific and medical interest in neural pathways and their connections have driven neuroscience and brain research for many decades so that specific systems and their feedback loops have been considered in detail. We review motor command systems in inver [...]

991 6990

Open Access Original Research

Analysis of Interpersonal Relationships of Social Network Users Using Explainable Artificial Intelligence Methods

Pavel Ustin ,

Fail Gafarov and

Andrey Berdnikov

Received: 27 April 2023; Published: 24 August 2023; doi: 10.21926/obm.neurobiol.2303180

Abstract

The emergence of the social networking phenomenon and the sudden spread of the coronavirus pandemic (COVID-19) around the world have significantly affected the transformation of the system of interpersonal relations, partly shifting them towards virtual reality. Online social networks have greatly expanded the boundaries of human interpersonal interaction and initiated processes of integration of different cultures. As a result, research into the possibilities of predicting human behavior through the characteristic [...]

1118 9359

Open Access Original Research

COVID-19 Milieu and Its Psychological Effects on the Environmental Performance

Nadia A. Abdelmegeed Abdelwahed ,

Mohammed A. Al Doghan and

Bahadur Ali Soomro

Received: 03 June 2023; Published: 22 August 2023; doi: 10.21926/obm.neurobiol.2303179

Abstract

COVID-19 brought significant challenges that have ruined almost all segments of the economy and the environment. The present paper explores the COVID-19 milieu and its impacts the environmental performance (EP). We targeted managers of the Small and Medium-sized enterprises (SMEs) of Saudi Arabia to get online responses. Using the path analysis, the findings reveal a significant negative effect of the factors such as perception of COVID-19 (PoCVD), innovation capability (IC), environmental concern (EC) and the fear [...]

610 4680

Open Access Original Research

“Welcome to Our World”: Experiences of Persons Living with Dementia Prior to and During the COVID-19 Pandemic

Melissa L. Harris-Gersten ,

Florence U. Johnson ,

Josephine R. Granner and

Susan N. Hastings

Received: 20 June 2023; Published: 10 August 2023; doi: 10.21926/obm.neurobiol.2303178

Abstract

People diagnosed with dementia are experts on living with the disease, yet their perspectives are often overlooked in research and practice. The pandemic has amplified health inequities among older adults, but the impact of the pandemic on the lived experience of people living with dementia remains unclear. This qualitative study used a series of 2 virtual focus groups with people living with dementia (N = 7) to explore challenging situations and emotions experienced by community-dwelling people living with dementi [...]

977 6255

|<<5 678 9 >>|

Showing 7 to 100 of 2574 (26 Page)

TOP