by Elham Amjad  and Babak Sokouti

Received: 15 December 2025;  Published: 24 August 2026;  doi: 10.21926/obm.genet.2603354

The pathology of PD is characterized by progressive degeneration of dopaminergic neurons, although the full regulatory network involved in this process is not yet fully established. The present research employed a multi-omic systems biology design, integrating transcriptomic, functional, epigenetic, and microRNA analyses to develop a mechanistic model [...]

by Tasya Fabiola Alim  , Valentinus Besin  and Mariana Wahjudi

Received: 04 January 2026;  Published: 24 August 2026;  doi: 10.21926/obm.neurobiol.2603348

Pituitary adenoma (PA) is a benign tumor, accounting for the majority of pituitary tumors. While extensive epidemiological data on PA exists globally, such data is limited in Indonesia. Epidemiological insights are crucial as disease patterns, including PA, can be ethnicity-dependent, and the incidence may differ across countries. This study aimed to [...]

by Nathália Dias Araújo  , Patrísia de Oliveira Rodrigues  , Mariana Fornazier Borges  , Anderson Gabriel Corrêa  , Gabriela Ciribelli Santos Pompêu  , Milla Alves Baffi  and Daniel Pasquini

Received: 19 May 2026;  Published: 24 August 2026;  doi: 10.21926/jept.2603014

Organosolv pretreatment is an attractive approach to disrupt the recalcitrant structure of lignocellulosic biomass from agroindustrial wastes, aiming to facilitate its bioconversion into valuable bioproducts. This study investigated the ability of an ethanol/water (1:1 v/v) organosolv pretreatment to improve the enzymatic digestibility of sugarcane [...]

by Terlumun Adagba

Received: 26 January 2026;  Published: 24 August 2026;  doi: 10.21926/rpm.2603006

The growing demand for sustainable, resource-efficient construction materials has heightened interest in agricultural waste-derived supplementary cementitious materials, among which cassava peel ash (CPA) has emerged as a promising alternative. This review critically evaluates cassava peel ash (CPA) as a potential pozzolanic material for cement and [...]

by Daming Zhang

Received: 11 August 2026;  Published: 23 August 2026;  doi: 10.21926/jept.2603013

In this paper, a method for operating AC microgrids in both off-grid or standalone and grid-connected modes is proposed to minimize the use of energy storage by increasing the number of PV panels and curtailing their output power. When the intensity of daylight decreases, power is imported from the main grid through an AC/DC/AC converter or solid-state [...]

by Maria Bisba  , Eirini Louizou  , Konstantinos Tzanakis  , Thomas Liehr  and Spiros Vittas

Received: 21 January 2026;  Published: 21 August 2026;  doi: 10.21926/obm.genet.2603353

Small supernumerary marker chromosomes (sSMCs) are rare chromosomal abnormalities with diverse outcomes and variable effects that can be detected prenatally. The clinical significance of low-level mosaic sSMCs is often uncertain, and postnatal follow-up is essential to assess phenotypic outcomes. A fetus in whom a low-level mosaic sSMC (8%) was detected [...]

by Daniel A. Encarnacion-Santos  , Andrey Vladimirovish Dubovoy  , Gennady Chmutin  , Egor Chmutin  , Emmanuel Batista-Geraldino  , Shahboz Boboev Ibrohimovich  and Adam Romanovish Mainer

Received: 28 April 2026;  Published: 21 August 2026;  doi: 10.21926/obm.neurobiol.2603347

Moyamoya disease (MMD) is a chronic, progressive cerebrovascular disorder characterized by stenosis of the terminal portion of the bilateral internal carotid arteries and the formation of an abnormal collateral vascular network at the skull base. This condition was first described by Suzuki and Takaku in 1969. This case report aims to describe the surgi [...]

by Helen Cyntia Mago  , Valentinus Besin  , Astuti Prodjohardjono  , Amelia Nur Vidyanti  , Waode Fifin Ervina  , Farizky Martriano Humardani  and Lisa Thalia Mulyanata

Received: 03 January 2026;  Published: 21 August 2026;  doi: 10.21926/obm.neurobiol.2603346

Alzheimer’s disease is one of the most prevalent neurodegenerative diseases among older people. Generally, there are two main pathologies of Alzheimer’s disease, including the accumulation of amyloid beta and the hyperphosphorylation of the microtubule-associated Tau protein in the brain. Recently, more studies have discovered that changes in the [...]

by Geise Camila Ribeiro  , Pedro Fernandes  , Floriatan Santos Costa  and Sandra Aparecida de Assis

Received: 14 December 2025;  Published: 21 August 2026;  doi: 10.21926/cr.2603010

The rising demand for enzymes with improved properties has driven continuous developments in enzyme technology, including enzymatic formulation. Enzyme formulation primarily aims to minimize losses in enzymatic activity during transport, storage and use. One strategy to mitigate enzyme inactivation is to include stabilizing agents or metal ions that [...]

by Vinayak Kaushal  and Allison Pham

Received: 31 December 2025;  Published: 20 August 2026;  doi: 10.21926/aeer.2603028

Sustainable construction practices and robust waste management strategies provide a viable pathway to mitigate these challenges. By integrating resource-efficient design, circular economy principles, and environmentally responsible technologies, the industry can significantly reduce its ecological burden. This paper presents a synthesis of environmental [...]

by Bubacar Embaló  , Jhenyfer Amanda Ciriaco Canhete  , Gabriel Schmitt da Cruz  , Daniela de Rossi Figueiredo  , Heloisa Godoi  and Ana Lúcia Schaefer Ferreira de Mello

Received: 30 October 2025;  Published: 19 August 2026;  doi: 10.21926/obm.geriatr.2603341

The study aimed to understand the provision of home dental care for homebound older adults within the context of primary healthcare. A mixed-methods, concurrent, parallel, and cross-sectional study was conducted. Quantitative data were collected from 123 homebound older adults through structured questionnaires and oral examinations and analyzed using [...]

by Aster Woldu Gebrearegay  , Melakuu Tesfaye  and Alemu Gizaw

Received: 14 February 2026;  Published: 19 August 2026;  doi: 10.21926/aeer.2603027

This study evaluated the dynamic performance of raw Cordia africana sawdust for hexavalent chromium (Cr(VI)) removal in a fixed-bed column system under varying operating conditions, using both synthetic solutions and real tannery wastewater. This represents the first comprehensive investigation combining fixed-bed operation, real wastewater validation [...]

by Kevin Curran  , Jack Kyle  and Lovepreet Singh

Received: 04 April 2026;  Published: 19 August 2026;  doi: 10.21926/rpse.2603017

The Internet of Things (IoT) is transforming industries and daily life by connecting billions of devices, enabling smart homes, cities and industrial systems. This rapid expansion, however, introduces significant cybersecurity vulnerabilities, leaving IoT systems increasingly exposed to both established and emerging attack techniques. This paper present [...]

by Affan Faisal  , Zain Tariq  , Harshini Maheswaran  and Maheswaran Pitchaimuthu

Received: 23 April 2026;  Published: 17 August 2026;  doi: 10.21926/obm.transplant.2603273

Liver transplantation is the definitive treatment for end-stage liver disease, acute liver failure, and selected hepatic malignancies, but its success is limited by a persistent shortage of suitable donor organs. This has driven increased use of extended criteria donors (ECDs), including steatotic and donation after circulatory death (DCD) grafts, which [...]

by İsmail Cem ÖZKURT

Received: 19 February 2026;  Published: 17 August 2026;  doi: 10.21926/aeer.2603026

Increases in greenhouse gas emissions, a key indicator of climate change, pose significant risks and uncertainties for the agricultural industry. From a theoretical supply-side perspective, greenhouse gas emissions may be associated with agricultural productivity losses and, consequently, with potential upward risks for producer prices. However, the [...]

by Elisavet Kouvidi  , Georgios Boutsikas  , Marina Kalomiraki  , Maria Devetzoglou  , Foteini Drimaki  , Ioannis Anagnostopoulos  and Evangelia-Faidra Triantafyllou

Received: 31 December 2025;  Published: 17 August 2026;  doi: 10.21926/obm.genet.2603352

The genetic hallmark of Acute promyelocytic leukemia (APL) is the balanced reciprocal translocation t(15;17)(q24;q21), resulting in the PML::RARα fusion gene. Although the majority of APL patients carry the typical t(15;17), variant translocations involving three or more chromosomes have also been described. We report a case of a 59-year-old man showin [...]

by Shivani Kohli  , Sujata Pandit Sharma  , Dolli Chauhan  and Nikita Singh

Received: 08 May 2026;  Published: 13 August 2026;  doi: 10.21926/aeer.2603025

A Considerable amount of peel, rind, core, and fibrous residues are produced from the processing of Jackfruit (Artocarpus heterophyllus Lam.), which are generally discarded, though they contain valuable lignocellulosic components. Limited information is available on the composition of the combined jackfruit processing waste stream. Thus, the present [...]

by Elham Amjad  and Babak Sokouti

Received: 17 December 2025;  Published: 11 August 2026;  doi: 10.21926/obm.neurobiol.2603345

Posttraumatic stress disorder (PTSD) poses a major mental health threat in the Middle East, where people experience ongoing conflict, displacement, and trauma. This study summarizes the use of computational and data-driven approaches, including machine learning (ML), biomarker identification, network analysis, and factor analysis, to understand, diagnos [...]

by Vincenzo Manca

Received: 27 March 2026;  Published: 11 August 2026;  doi: 10.21926/obm.neurobiol.2603344

This paper proposes a general theory of cognitive systems that inverts the conventional relationship between information and knowledge. While classical approaches define knowledge as the byproduct of processed information, we establish knowledge as a primitive concept and formulate information as a measure emerging from the process of assimilating knowl [...]

by Leena Rawal  and Vamshi Krishna Thamtam

Received: 15 April 2026;  Published: 10 August 2026;  doi: 10.21926/obm.genet.2603351

Acute myeloid leukemia (AML) represents a clinically and genetically heterogeneous group of hematologic malignancies. Among the less frequently encountered cytogenetic abnormalities are jumping translocations (JTs), in which a segment from a donor chromosome relocates to multiple recipient chromosomes. Although uncommon, these events have been described [...]