Open Access Original Research

A Clinical Validity-Preserving Machine Learning Approach for Behavioral Assessment of Autism Spectrum Disorder

Received: 31 May 2022;  Published: 30 September 2022;  doi: 10.21926/obm.neurobiol.2203138


Autism spectrum disorder (ASD) is a neuropsychiatric disorder associated with critical challenges related to social, communication, and behavioral issues. Recent studies have proposed machine learning (ML) techniques for rapid and accurate assessment of ASD. However, the mismatch between the ML techniques and the clinical basis of ASD assessment reduces [...]

Open Access Original Research

Implementation of a Dynamic Thermal and Illuminance Control System in Responsive Façades: Shading Study

Received: 30 May 2022;  Published: 29 September 2022;  doi: 10.21926/aeer.2203038


This study evaluates three shading configurations designed and tested in a preliminary stage of responsive shading device development. The strategy is based on trigonometric relationships focused on solar angles at any given moment. The configurations are thus related to the ratio of the window area shaded by a responsive brise-soleil that provides [...]

Open Access Research Article

Cytoplasmic Microinjection of piggyBac Transposase mRNA and Transposon Vectors for Efficient In Vitro Production of Transgenic Porcine Parthenotes

Received: 07 July 2022;  Published: 29 September 2022;  doi: 10.21926/obm.genet.2203166


The efficient production of transgenic (Tg) piglets has remained a challenge in the field of domestic animal studies. Unlike mice, the pronuclei of pig zygotes cannot be easily studied because of the abundance of lipid droplets. Therefore, the zygotes must be briefly centrifuged before pronuclear injection (PNI) to move the lipid droplets to the periphe [...]

Open Access Original Research

Catalytic Co-gasification of Lignites Blended with a Forest Residue under the Carbon Dioxide Stream

Received: 24 May 2022;  Published: 29 September 2022;  doi: 10.21926/cr.2203031


The present study investigated the co-gasification of two different lignites blended with the forest residue collected from the land restoration activity sites of open-pit mines located in the region of the Ptolemais basin in North Greece performed under the carbon dioxide stream. All samples were devolatilized in a fixed bed unit prior to the gasificat [...]

Open Access Original Research

Computerized Assessment of Cognitive Development in Neurotypical and Neurodivergent Children

Received: 05 July 2022;  Published: 28 September 2022;  doi: 10.21926/obm.neurobiol.2203137


This study aims to observe the differences in the shared intentionality magnitude in mother-child dyads with neurotypical (NT) children and neurodivergent (ND) children aged 3-6 years. The quality of shared intentionality in infancy is associated with cognitive development. Our results showed that ND children scored six times higher (on average) in [...]

Open Access Short Report

Creation of an Operational Dashboard to Document Implementation of 4M’s into Primary Care in a Geriatric Patient-Centered Medical Home

Received: 05 June 2022;  Published: 28 September 2022;  doi: 10.21926/obm.geriatr.2203205


Many health systems have joined the Age-Friendly Health Systems movement to provide every older adult safe, high-quality care aligned with what matters most. Becoming an Age-Friendly Health System means that hospitals and health care systems reliably use a set of evidence-based practices known as the “4M’s” – What Matters, Medication, Mentation [...]

Open Access Original Research

The Technology of Upward Capillary Formation of Waste for Creating a Deposit before Land Reclamation

Received: 08 June 2022;  Published: 27 September 2022;  doi: 10.21926/aeer.2203037


Mineral resources in the subsoil are classified as exhaustible. One of the ways to potentially replenish the sources of mineral resources is presented in the materials of these studies. In this article, we studied the natural formation in the bowels of the array of zones of high concentrations of compounds of useful components. We aimed to develop the [...]

Open Access Original Research

Historical Evolution and Scenarios Up to 2050 of Heating Energy Consumption and CO2 Emissions of Residential Buildings in Vienna

Received: 24 June 2022;  Published: 27 September 2022;  doi: 10.21926/jept.2203030


Today, the building sector poses a major problem concerning fossil fuel energy consumption and the corresponding emissions of local pollutants and global greenhouse gases (GHG). In addition, an increasing number of people are living in urban areas, and it is becoming challenging to provide the necessary living space and energy for heating in fast-growin [...]

Open Access Original Research

Hypnotic Regression as an Autoethnographic Modality for Exploring Adverse Childhood Experiences as Proposed Effectors of Chronic Adult Obesity - Selected Case Studies

Received: 09 March 2022;  Published: 26 September 2022;  doi: 10.21926/obm.icm.2203046


Much has been written about the aetiological role of Adverse Childhood Experiences (ACEs) in the development of chronic adult physical and emotional health problems but current screening methods utilising questionnaires and formal interviewing often fail to show consensus across populations and surveys. This paper proposes that hypnotic regression might [...]

Open Access Research Article

The Role of Tribal Leaders/Traditional Leaders in Regulating Land Use and Biodiversity Among the Gurune-Speaking People of the Upper East Region in Ghana

Received: 29 April 2022;  Published: 26 September 2022;  doi: 10.21926/aeer.2203036


Regulating land use and the biodiversity of a region requires lasting accords between those who make the decisions and those who are affected by the rules and regulations. In Africa, these accords depend on the effectiveness of the collective efforts of the representatives of the legal authorities and the civil society (the traditional leaders in the [...]

Open Access Research Article

Neuroprotective (Antioxidant, Antiamyloidogenic, and Antiexcitatory) Effects of TrévoTM against Cadmium Chloride Neurotoxicity in Adult Male Wistar Rats

Received: 29 May 2022;  Published: 26 September 2022;  doi: 10.21926/obm.neurobiol.2203135


Cadmium (Cd) is a heavy metal that is deleterious to brain development as it increases brain aging. Trévo is a multi-herbal supplement that provides various health benefits, including boosting the immune system and detoxification. In this study, we investigated the neuroprotective effects of Trévo against the neurotoxic effects of cadmium chloride [...]

Open Access Original Research

Effect of Microwave Radiation on the Development of a Porous Aluminum Carrier of the Active Mass of Catalysts in Heterogeneous Catalytic Reactions

Received: 24 June 2022;  Published: 26 September 2022;  doi: 10.21926/cr.2203030


In this study, we prepared a fine-grained, aluminum-reinforced alumina support matrix of the active mass of catalysts, which showed activity in heterogeneous catalytic reactions stimulated by electromagnetic radiation in the microwave range. The support absorbed microwave radiation of 2.45 GHz. We compared the textural characteristics of samples of [...]

Open Access Interview

An Interview with Dr. Francisco J. Barrantes

Received: 22 September 2022;  Published: 26 September 2022;  doi: 10.21926/obm.neurobiol.2203136

Open Access Original Research

A Qualitative Study Exploring the Impact the Self-Compassion App Has on Levels of Compassion, Self-Criticism, and Wellbeing

Received: 25 May 2022;  Published: 26 September 2022;  doi: 10.21926/obm.icm.2203045


Self-guided, smartphone apps may be helpful in reducing symptoms associated with psychological distress and may boost wellbeing, and levels of compassion. To our knowledge this is the first study to examine the impact a 28-day app based on Compassion Focused Therapy and Compassionate Mind Training has on participant’s levels of compassion, wellbeing [...]

Open Access Review

Newborn Screening in Gaucher Disease: A Bright and Complicated Future

Received: 20 July 2022;  Published: 26 September 2022;  doi: 10.21926/obm.genet.2203165


Gaucher disease (GD) is one of the most common lysosomal storage disorders resulting from biallelic mutations in the GBA1 gene, causing a dysfunction of the lysosomal hydrolase, glucocerebrosidase (acid-β-glucosidase; E.C Clinical manifestations are heterogenous and can include splenomegaly, anemia, and neurological impairments in the case [...]

Open Access Technical Note

Successive Detection of Telomerase by IHC and Assessment of Telomere Length by Q-FISH in Paucicellular Cumulus Samples from Cumulus-Oocyte Complexes Obtained in Assisted Reproduction Programs

Received: 13 May 2022;  Published: 23 September 2022;  doi: 10.21926/obm.genet.2203164


This paper suggests an approach for the use of a single paucicellular histological sample to investigate two characteristics indicative of the cell’s functional potential: 1) the content of telomerase reverse transcriptase (TERT) and 2) the telomere length. An algorithm has been suggested for the successive detection of the catalytic telomerase subuni [...]

Open Access Original Research

Modeling of Information Processing in Biomorphic Neuroprocessor

Received: 14 June 2022;  Published: 22 September 2022;  doi: 10.21926/obm.neurobiol.2203134


In the present study, we present the results of the modeling of incoming information processing in a neuroprocessor that implements a biomorphic spiking neural network with numerous neurons and trainable synaptic connections between them. Physico-mathematical models of processes of encoding information into biomorphic pulses and their decoding following [...]

Open Access Review

Microbial Cyclodextrin Glycosyltransferases: Sources, Production, and Application in Cyclodextrin Synthesis

Received: 11 June 2022;  Published: 22 September 2022;  doi: 10.21926/cr.2203029


Cyclodextrin glycosyltransferase (CGTase) is a multifunctional enzyme that hydrolyzes the α-glycosidic bond between two sugar molecules and synthesizes cyclodextrins (CDs) and other transglycosylation products. It is a ubiquitously present extracellular enzyme that offers the CGTase-producing organism the sole right onto starch substrates over other [...]

Open Access Review

Outcomes of Ecuador’s Rights of Nature for Nature’s Sake

Received: 30 March 2022;  Published: 22 September 2022;  doi: 10.21926/aeer.2203035


The rights of nature have been widely discussed at a philosophical level for a long time, but examples of its practical application are quite rare. Ecuador is the first country to incorporate this concept into its constitutional foundation and put the theory into practice. However, implementing entirely justifiable rights of nature is hindered by factor [...]

Open Access Original Research

Open-Label Study to Evaluate the Response to Homeopathic Treatment of Psoriasis

Received: 12 August 2022;  Published: 21 September 2022;  doi: 10.21926/obm.icm.2203044


Patients with psoriasis commonly opt for homeopathic treatment. However, no study has assessed the response to homeopathic treatment by using standardized disease-specific scales, and the findings are based on clinical assessments only. The objective of this study was to evaluate the response to the individualized homeopathic treatment of psoriasis [...]

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Guest Editors: Ugochukwu N. Ikeogu

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