Open Access Review

Neurotoxicity Following Exposure to Micro and Nanoplastics

Received: 13 December 2024;  Published: 16 March 2025;  doi: 10.21926/obm.neurobiol.2501277

Abstract

The pervasive presence and enduring existence of micro and nanoplastics in the environment render their exposure to humans and aquatic creatures unavoidable. Research indicates these tiny plastic particles can be taken in by aquatic beings and mammals. Once within the body, micro and nanoplastics have the capability to infiltrate the brain, although [...]

Open Access Original Research

A Systems Biology Approach to Understanding Delirium Pathophysiology and Identifying Natural Compounds for Potential Therapeutic Purposes

Received: 30 October 2024;  Published: 14 March 2025;  doi: 10.21926/obm.neurobiol.2501276

Abstract

Delirium is an acute neurocognitive disorder marked by disruptions in attention, cognition, and awareness, particularly prevalent among older and critically ill patients. This study applies a systems biology framework to dissect the molecular underpinnings of delirium and evaluate natural compounds for potential therapeutic roles. Through bioinformatics [...]

Open Access Original Research

How Viniyoga Supports Health and Healing

Received: 17 January 2025;  Published: 14 March 2025;  doi: 10.21926/obm.icm.2501014

Abstract

In this qualitative study, the impact of therapeutic Viniyoga on health and healing was explored from the perspective of 14 Viniyoga therapists who were interviewed on their perceptions of how yoga therapy contributes to the health and healing of their clients. A philosophical definition of Therapeutic Viniyoga was developed. Three themes related to [...]

Open Access Original Research

Studying the Cognitive and Behavioural Dynamics of Psychopathy

Received: 04 December 2024;  Published: 14 March 2025;  doi: 10.21926/obm.neurobiol.2501275

Abstract

The relevance of studying the cognitive and behavioral dynamics of psychopathy lies in its importance for improving diagnosis, therapeutic interventions, and reducing crime, thereby contributing to public safety. This study aimed to investigate how cognitive and behavioral mechanisms influence psychopathy. A combination of methods was employed, includin [...]

Open Access Review

Review of Heterotopic Heart Transplantation Models in Rats

Received: 21 October 2024;  Published: 14 March 2025;  doi: 10.21926/obm.transplant.2501242

Abstract

Heterotopic heart transplantation (HHT) in rats is a valuable tool for cardiac transplantation research. While abdominal HHT has been established in rats for nearly 90 years, novel approaches involving cervical and femoral techniques have also been explored. The abdominal HHT model, despite its long history, is technically demanding and has a steep [...]

Open Access Review

Allogeneic Stem Cell Transplantation: Current Status and Future Directions

Received: 03 August 2024;  Published: 12 March 2025;  doi: 10.21926/obm.transplant.2501241

Abstract

Allogeneic stem cell transplantation (allo-SCT) improves the treatment of hematopoietic cancer and non-malignant disease. In this case, stem cells from a genetically similar but not identical donor may stimulate immune-mediated tumor cell destruction. Allogeneic stem cell transplantation, or allo-SCT, has significantly extended the life expectancy of [...]

Open Access Original Research

Impacts of Carbon Capture and Storage (CCS) Technology on the Sustainability of Coal-Based Power Generation Pathways

Received: 16 November 2024;  Published: 10 March 2025;  doi: 10.21926/rpse.2501003

Abstract

Carbon capture and storage (CCS) technology mitigates greenhouse gas (GHG) emissions. However, comprehensive studies assessing the sustainability of coal-based power generation (CBPG) with CCS remain limited. This study focuses on developing comparative sustainability indicators across the entire life cycle of CBPG integrated with CCS technology. Sixt [...]

Open Access Original Research

A Pilot Study Testing the Clinical Congruency of Healthcare Providers to Use a Clinical Decision Support Tool to Assess Falls in Older Adults

Received: 30 January 2024;  Published: 10 March 2025;  doi: 10.21926/obm.geriatr.2501303

Abstract

This research sought to determine feasibility for RNs to use the Post Fall Index™ (PFI) and to determine if an RN could identify underlying causal event factors for falls, would it be congruent with other providers (advanced practice nurse [APN], physician [MD])? PFI data from 23 falling residents of a nursing home were compiled into clinical vignette [...]

Open Access Research Article

Design and Management of Renewable Energy Systems for Isolated Communities with No Grid Connection

Received: 10 October 2024;  Published: 07 March 2025;  doi: 10.21926/jept.2501005

Abstract

The growing demand for energy and the need to reduce dependence on non-renewable sources have driven the research and application of sustainable technologies. In this context, an integrated solution that combines distributed energy generation from renewable sources, such as wind and hydro, with efficient management of household energy consumption is [...]

Open Access Original Research

Design and Simulation of Computational Models of Hybrid Scaffolds Representative of Subchondral Bone and Hyaline Cartilage

Received: 22 August 2024;  Published: 07 March 2025;  doi: 10.21926/obm.transplant.2501240

Abstract

Tissue engineering offers alternatives when it comes to health problems such as trauma or pathologies. One of them is the scaffolds, which provide a favorable architecture, mechanics, and biocompatibility for the fixation of cells. Therefore, the following research aims to design and simulate scaffolds with mixed geometric structures to create a hybrid [...]

Open Access Original Research

Computer-Aided Study on Metal Complexes with Benzohydrazide Schiff Base as Potential Bacterial and Fungi Inhibitors

Received: 22 October 2024;  Published: 06 March 2025;  doi: 10.21926/rpse.2501002

Abstract

The biochemical properties of metal complexes containing benzo hydrazide Schiff base have been reported by numerous researchers worldwide in various ways. In this work, the evaluation of biochemical roles of the metal complexes with benzo hydrazide Schiff base activity as anti-gram positive and gram-negative bacteria, as well as antifungal agents, were [...]

Open Access Original Research

Soil Treatment from Hazardous Particles Using Designed Nanosensors: A Physical and Chemical Analysis

Received: 11 November 2024;  Published: 06 March 2025;  doi: 10.21926/cr.2501003

Abstract

Being critical to achieving Sustainable Development Goals (SDGs) of the United Nations, strengthening understanding of the properties and processes of soil at national and regional scales is imperative. The target of this research is removing transition metals of Cr, Mn, Fe, Zn, W, Cd from soil due to nanomaterial-based boron nitride nanocage (B5N1 [...]

Open Access Original Research

A Pilot Double-Blind Randomised Sham-Controlled Trial of Paraesthesia-Free Burst Waveform Spinal Cord Stimulation in a Small Case Series of Patients with Chronic Spinal or Limb Pain

Received: 24 November 2024;  Published: 05 March 2025;  doi: 10.21926/obm.neurobiol.2501274

Abstract

The aim of this study was to identify methodological issues that might influence comparison of burst versus sham spinal cord stimulation for treating chronic pain. Six patients with an implanted BurstDR spinal cord stimulator were assessed double-blind during eight 3-to-4-day ON or OFF cycles over a 28-day period. The stimulator was switched off during [...]

Open Access Original Research

Exploring Farmers’ Motivators and Barriers to Adopting Stress Management Behaviors

Received: 30 September 2024;  Published: 05 March 2025;  doi: 10.21926/obm.icm.2501013

Abstract

Farmers experience high levels of stress, with negative sequelae including physical illness, depression, anxiety, and suicide. Despite this, farmers are often reluctant to adopt stress management behaviors. This study collected survey data on motivators and barriers to stress management behavior change among farmers from 162 participants at a regional [...]

Open Access Case Report

Therapeutic Use of Auto-Induced Cognitive Trance in a Chronic Pain Setting: A Case Study Using Mixed Methodology

Received: 14 August 2024;  Published: 05 March 2025;  doi: 10.21926/obm.icm.2501012

Abstract

Auto-induced cognitive trance (AICT) is a method for voluntarily entering modified state of consciousness. The therapeutic implications of AICT are still unknown. Since complementary approaches based on modified states of consciousness are recognized to be beneficial for patients suffering from chronic pain (e.g., hypnosis, meditation), we here present [...]

Open Access Original Research

Parenting Behavior and Early Childhood Mental Health: Cortisol Awakening Response as a Moderator of Child Internalizing and Externalizing

Received: 02 September 2024;  Published: 04 March 2025;  doi: 10.21926/obm.icm.2501011

Abstract

Certain observable parenting behaviors contribute to the risk of children developing internalizing and externalizing problems. Yet parenting behaviors do not affect all children uniformly and effects may depend on identifiable child characteristics. One factor is a child’s biological sensitivity to the caregiving environment, an indicator of which [...]

Open Access Review

The Role of Pulmonary Rehabilitation in Lung Transplantation for Cystic Fibrosis

Received: 11 December 2024;  Published: 03 March 2025;  doi: 10.21926/obm.transplant.2501239

Abstract

Cystic fibrosis (CF) is a genetic disorder that significantly impacts respiratory function, leading to progressive lung damage and ultimately respiratory failure. Lung transplantation (LTx) is a critical intervention for CF patients with end-stage lung disease, offering improved survival and quality of life. Pulmonary rehabilitation (PR) plays a pivotal [...]

Open Access Original Research

Comparative Study on Mental Health Parameters among Yoga and Non-Yoga Practitioners in Older Adults Amidst COVID-19 Pandemic

Received: 14 October 2024;  Published: 03 March 2025;  doi: 10.21926/obm.geriatr.2501302

Abstract

The COVID-19 pandemic has increased stress and disrupted routines affecting the psycho-social health of older adults, a vulnerable section of the population. Yogic practices have shown the potential to reduce stress, inflammation, and psychological health among other benefits. Hence, we explored the benefits of regular yoga practice on specific key [...]

Open Access Research Article

Motivation to Cultivate Social Ties and Diurnal Cortisol: Testing the Mediating Effect of Social Embeddedness in Chinese Older Adults

Received: 20 July 2024;  Published: 02 March 2025;  doi: 10.21926/obm.geriatr.2501300

Abstract

Based on a framework derived from theories of social integration and health, this study examined the relationships between motivation to cultivate social ties or network cultivation, and diurnal salivary cortisol in Chinese older adults. The main objective was to determine the behavioral mechanism that translated a higher motivation to cultivate social [...]

Open Access Original Research

Potential CRISPR-Cas9-based Antiviral Activity Against Hepatitis C Virus in Liver Cancer

Received: 04 July 2024;  Published: 28 February 2025;  doi: 10.21926/obm.genet.2501287

Abstract

Hepatitis C virus (HCV) is a primary global health concern, and though therapeutic options have improved, no very effective vaccine is available despite decades of research. The health and vitality of the organism are related to the result of homeostatic regulation of the internal environment. In contrast, it follows that disruption of homeostatic mecha [...]

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