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Table of Content

Open Access Original Research

The Relationship between Anger, Stress, Psychological Distress and Mood Disorders among Entrepreneurs

Received: 18 December 2024;  Published: 26 May 2025;  doi: 10.21926/obm.neurobiol.2502288

Abstract

The present study investigates the association between anger, stress, psychological distress and mood disorders among Egyptian entrepreneurs. Approach-wise, the study is quantitative, and its cross-sectional data were collected using a questionnaire. The study’s respondents are Egyptian entrepreneurs involved in several business activities. Hence, the study concluded based on 286 valid responses. We used analysis of moment structures (AMOS) software, where we conducted path analysis to conclude the results. C [...]

1306 9006

Open Access Original Research

In Silico Evaluation of Anti-SARS-CoV-2 Bioactive Compounds from Jatropha curcas

Received: 12 March 2025;  Published: 25 May 2025;  doi: 10.21926/obm.genet.2502295

Abstract

Jatropha curcas L., a medicinal shrub renowned for its diverse phytochemicals, has been traditionally used to treat various ailments, including ulcers, neoplasms, and dermatological conditions. Despite its pharmacological promise, its potential against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) remains unexplored. This study investigates the antiviral efficacy of J. curcas phytochemicals targeting the SARS-CoV-2 main protease (Mpro), a critical enzyme for viral replication, using advanced computat [...]

1211 6193

Open Access Original Research

The Importance of Specialized Inpatient Medical Stabilization for Weight Restoration of Individuals with Extreme Eating Disorders

Received: 19 December 2024;  Published: 23 May 2025;  doi: 10.21926/rpn.2502012

Abstract

Inpatient care is a significant contributor to the health-care costs associated with the treatment of individuals with eating disorders (EDs). This study seeks to better understand the treatment outcomes of individuals with extreme EDs requiring inpatient medical stabilization at specialized medical versus nonspecialized medical units. Patients transferred via air ambulance to ACUTE Center for Eating Disorders and Severe Malnutrition (specialized care) from an outside hospital (nonspecialized care) between January [...]

1170 8942

Open Access Original Research

Quantitative Evaluations on Harmonic and Anharmonic Lattice Thermal Capacity of Polymers

Received: 28 December 2024;  Published: 22 May 2025;  doi: 10.21926/rpm.2502008

Abstract

So-called ‘Generalized Skettrup Model(s)’ (GSMs) of different (1D, 2D, 3D) spatial dimensionalities are used at simulations on temperature-dependent harmonic and anharmonic fractions of lattice thermal capacity of polyethylene and polypropylene with crystalline and/or amorphous atomic structures of limited spatial extents. Basic equations of the GSM slot in explicitly quantization effects of the single-particle and many-particle energy levels of spatially confined phonons. The harmonic lattice thermal c [...]

1036 5490

Open Access Case Report

Unraveling and Expanding the Genotypic Spectrum of Kabuki Syndrome with Identification of de Novo Protein-Truncating Mutations in the KMT2D Gene: Insights into the Role of Premature Stop Codons in the Etiology of the Disorder

Received: 16 January 2025;  Published: 21 May 2025;  doi: 10.21926/obm.genet.2502294

Abstract

Kabuki Syndrome (KS) is a rare, multisystem congenital disorder with five foremost clinical manifestations encompassing dysmorphic facial characteristics, postnatal growth constraint, craniofacial/skeletal anomalies, mild to moderate intellectual disability, and dermatoglyphic abnormalities. We analyzed two unrelated Iranian patients suspected of having KS using whole-exome sequencing. An in silico analysis was performed to evaluate the potential effects of the discovered variants on the structure and function of t [...]

1142 6559

Open Access Original Research

The Intra-Institutional Waste Management in Montevideo Healthcare Centers

Received: 23 September 2024;  Published: 20 May 2025;  doi: 10.21926/aeer.2502023

Abstract

Healthcare Waste (HCW) management is a pressing challenge in Latin America, where insufficient regulatory enforcement, poor segregation practices, and the lack of accurate generation data hinder sustainable waste management. This study presents a methodological proposal for the internal management of HCWs in Healthcare Centers (HCCs) in Uruguay, based on Decree 586/009 and developed through a situational diagnosis conducted at the Hospital de Clínicas "Dr. Manuel Quintela." The diagnosis involved the qualitative an [...]

1257 7004

Open Access Original Research

“It Seems to Sort of Wash My Brain Out”: The Experiences of Open-Water Swimmers with Depression

Received: 05 March 2025;  Published: 19 May 2025;  doi: 10.21926/obm.icm.2502022

Abstract

Depression is a leading cause of disability with many individuals experiencing recurrent episodes of depression across their lifetime. Existing treatment approaches have varied degrees of effectiveness, and the value of social prescribing practices is being recognised. Given the persistent nature of depression, many individuals seek out alternative methods to manage their own symptoms. Open-water swimming is becoming increasingly popular as a means of supporting mental health. There is an emerging evidence base ind [...]

1032 9873

Open Access Original Research

The Contribution of Dietary Fatty Acids to Prediction of All-Cause Mortality in a Cohort of Middle-Aged Men Followed-Up for 61 Years Until Extinction

Received: 09 November 2024;  Published: 19 May 2025;  doi: 10.21926/rpn.2502011

Abstract

To describe the contribution of three classes of dietary fatty acids to all-cause mortality and age at death among middle-aged men followed up for 61 years until extinction. The cohort comprised 1712 men aged 40-59 years at entry examination in 1960, belonging to the Italian Rural Areas of the Seven Countries Study of Cardiovascular Diseases. A dietary survey allowed to estimate dietary fatty acids [saturated (SAFA), mono-unsaturated (MUFA), poly-unsaturated (PUFA) and their ratios (M/S, P/S)] that were fed as poss [...]

1113 4407

Open Access Original Research

Illness Perceptions and Their Impact on Treatment Adherence among Renal Transplant Patients in the COVID-19 Pandemic

Received: 17 December 2024;  Published: 16 May 2025;  doi: 10.21926/obm.transplant.2502249

Abstract

Although immunosuppressive drugs are essential and effective in improving the health status of renal transplant patients, they also make them more vulnerable to the risk of infection with COVID-19, which has become a significant concern for many patients. Perhaps this is what makes their way of thinking and perception impact their adherence to taking immunosuppressants. Therefore, this study reveals the possibility of an impact of illness perception and some sociodemographic and clinical factors on treatment adhere [...]

865 4457

Open Access Review

Exclusive Enteral Nutrition as an Effective Treatment in Inflammatory Bowel Disease

Received: 17 November 2024;  Published: 13 May 2025;  doi: 10.21926/rpn.2502010

Abstract

In recent years, the incidence of Inflammatory Bowel Disease (IBD) has risen significantly in the Western population, pointing toward the potential influence of environmental and dietary factors. In order to explain this, some research on nutritional therapy identifies exclusive enteral nutrition (EEN) as a highly effective approach for managing IBD in children. This treatment achieves high remission rates; more specifically, some clinical trials have reported remission rates from 70% to 100%. EEN not only facilita [...]

1418 19975

Open Access Review

Gaseous Biofuels in Biorefineries: Biomethane

Received: 20 February 2025;  Published: 13 May 2025;  doi: 10.21926/jept.2502010

Abstract

The global production of biomethane is rapidly emerging as a sustainable alternative to fossil fuels for energy generation. Biogas, where methane (CH4) is usually one of the main components, is generated through the anaerobic digestion (AD) of various organic substrates, including animal manure, organic wastes, and wastewater. The efficiency of the AD process depends on key operational parameters and reactor designs that optimize microbial activity and gas yield. However, inhibitory compounds such as heavy metals, [...]

1674 9414

Open Access Research Article

Moderate Exercise Suppresses Tumor Growth and Progression through Regulating Cytokines

Received: 21 January 2025;  Published: 12 May 2025;  doi: 10.21926/obm.icm.2502021

Abstract

Evidence suggests that regular moderate exercise can improve symptoms of depression and may enhance immune function, with an interesting role in cancer prevention and improved cancer-related prognosis; however, over-exercising may lead to overtraining and generate psychological symptoms that mimic depression, and may impair immune function. In this study, we chose swimming as an exercise form to conduct research. Swimming groups were divided into 5, 20, and 60 min day-1, and open field tests (OFT) were used to asse [...]

1227 5255

Open Access Original Research

Using a Gamification Approach to Enhance Continued Use of Assistive Technology Intervention in Persons Living with Dementia

Received: 18 October 2024;  Published: 09 May 2025;  doi: 10.21926/obm.geriatr.2502311

Abstract

Assistive technology (AT) interventions have shown promising results in supporting cognitive, social, and physical activities in persons living with dementia (PLWD) and their caregivers. Despite strong evidence of the effectiveness of AT, PLWD and their caregivers can disengage with the technology after it is used for a time – i.e., the “stickiness challenge”. Diminished use of AT reduces the opportunity for it to have optimal impact. We asked whether the opportunity to engage in cognitive games may enhance continu [...]

1338 6345

Open Access Review

Love in the Time of COVID: Psychiatric Outcomes Related to Oxytocin and the “Endocrine Organ”

Received: 09 February 2025;  Published: 09 May 2025;  doi: 10.21926/obm.neurobiol.2502287

Abstract

The COVID-19 pandemic was an eye-opener for many medical disciplines. It highlighted viral exploitation of physiological cellular processes, including endocytosis and cellular senescence. These pathways play an essential role in cancer, neurodegenerative disorders, and schizophrenia (SCZ). Oxytocin, commonly called the “love hormone,” is produced in the posterior hypothalamus and is crucial for various physiological processes, including social intelligence, sexual activity, and metabolism. Many viruses, [...]

938 5104

Open Access Review

An Overview of the Hydrocarbon Sector in India for Carbon Capture Scope

Received: 28 November 2024;  Published: 07 May 2025;  doi: 10.21926/aeer.2502022

Abstract

The hydrocarbon sector in India plays a pivotal role in the country's energy landscape, encompassing exploration, production, refining, and distribution activities. This abstract provides a concise overview of the sector's current status, challenges, and prospects. India's hydrocarbon reserves range from conventional to unconventional sources, with significant potential yet to be tapped. However, the sector faces challenges such as declining production from mature fields, technological limitations in ex [...]

1676 10804

Open Access Interview

An Interview with Dr. Emanuele Sgambitterra

Received: 05 May 2025;  Published: 06 May 2025;  doi: 10.21926/rpse.2502009

791 5401

Open Access Project Report

Test Site for Small Wind Turbines – Technical and Logistical Issues of a Decade-Long Project

Received: 31 October 2024;  Published: 05 May 2025;  doi: 10.21926/jept.2502009

Abstract

This work addresses the main results of a test site for small wind turbines (SWTs) located in Patagonia, and the development of the measurement systems involved, including the uncertainties calculations according to applicable IEC standards. Due to market evolution for over a decade, the test systems evolved from battery-charging SWTs to grid-connected units. The test site, developed and managed by state-owned INTI (National Institute for Industrial Technology), was established in 2012 and received support from the [...]

1461 8151

Open Access Original Research

Environmental Impacts of Different Electricity Production Scenarios in France

Received: 20 September 2024;  Published: 30 April 2025;  doi: 10.21926/jept.2502008

Abstract

This study focuses on the environmental impacts of the electricity production scenarios proposed for France for 2060 by the French electricity network manager, RTE. They consider an increasing electricity consumption and a production without fossil fuels, essentially based on wind, photovoltaic, hydraulic, and, for some, nuclear power. The total power to install is significantly higher than the current one; it is higher in the scenarios that rely more on photovoltaic and less on nuclear. Renewable energies require [...]

1370 11799

Open Access Editorial

Battlefield Acupuncture: Remembering a Pioneer and a Friend—In Memory of Dr. Richard C. Niemtzow, MD PhD MPH (1942–2025)

Received: 26 April 2025;  Published: 29 April 2025;  doi: 10.21926/obm.icm.2502020

Abstract

This contribution honours the life and legacy of Dr. Richard C. Niemtzow (1942–2025), the founder of Battlefield Acupuncture (BFA) – a method that combines military medicine and traditional Eastern healing principles. Developed in the early 2000s for rapid, drug-free pain relief, BFA has since gained international recognition for its effectiveness and simplicity. The author reflects on the scientific collaboration with Dr. Niemtzow, which included advanced neurophysiological studies demonstrating BFA’s impact on pa [...]

855 5958

Open Access Interview

An Interview with Prof. Dr. Roy G. Beran

Received: 27 April 2025;  Published: 28 April 2025;  doi: 10.21926/obm.geriatr.2502310

716 3017

Open Access Review

Dysphagia in the Elderly, A Tough Issue to Swallow

Received: 12 December 2024;  Published: 28 April 2025;  doi: 10.21926/obm.geriatr.2502309

Abstract

Dysphagia in the geriatric population, age 65 or older, is increasingly common and a growing concern among healthcare providers. Not only can it critically impact quality of life, but it can also lead to clinically significant malnutrition, hospitalizations, increased length of stays, and has been shown to impact mortality. A multi-disciplinary approach to assess oral, pharyngeal, and esophageal etiologies is key to guiding targeted management, which can include behavioral modifications, medications, and endoscopic [...]

4052 22545

Open Access Original Research

Characterization of Patients with Functional Syndromes and Paradoxical Response to Hypnotic Relaxation

Received: 30 July 2024;  Published: 27 April 2025;  doi: 10.21926/obm.icm.2502019

Abstract

Hypnotherapy is effective for treating functional symptoms; however, some studies describe a paradoxical response to hypnotic relaxation. We hypothesized that functional patients who: 1) are aware of a stressful antecedent event and 2) recognize that stress is causing or exacerbating their symptoms would have reduced symptom-severity with hypnotic relaxation, whereas patients who do not perceive a stressful antecedent and do not recognize stress as causing symptoms, would more commonly experience paradoxical respon [...]

834 5143

Open Access Research Article

Analysis of Global Scientific Production on Health Service Waste through Bibliometric and Scientometric Indicators

Received: 19 October 2024;  Published: 27 April 2025;  doi: 10.21926/aeer.2502021

Abstract

Inadequate management of healthcare waste represents a significant challenge to public health and the environment. This study aims to analyze global scientific production on healthcare waste using bibliometric and scientometric indicators, providing a comprehensive overview of research trends and areas of interest. Data from academic databases were used to map the temporal distribution of publications, identify the leading countries, institutions, and researchers involved, and evaluate collaboration networks and jo [...]

1248 5169

Open Access Original Research

Location, Season and Source Effects on Gross Composition of Raw Cow’s Milk Across Khartoum State, Sudan

Received: 06 April 2024;  Published: 27 April 2025;  doi: 10.21926/rpn.2502009

Abstract

This study was conducted to investigate the effect of sources. locations and seasons (late summer and winter) on the chemical composition of cow milk collected from Khartoum State. The samples were collected randomly in the morning or the evening. Two hundred and seventy milk samples were collected from farms (90 samples), groceries (90 samples) and vendors (90 samples) in Khartoum State during the late summer and winter seasons, 135 samples each. The milk samples were kept in cool cracked ice and transported immed [...]

961 6330

Open Access Review

What Is the Current Status of Single Lung Transplantation? A Literature Review

Received: 19 September 2024;  Published: 27 April 2025;  doi: 10.21926/obm.transplant.2502248

Abstract

Lung transplantation (LTx) is the gold standard for the surgical treatment of end-stage lung disease. Ongoing discussions persist whether single lung transplantation (SLT) or bilateral lung transplantation (BLT) lead to better patient outcomes and quality of life. This study analyzed 58 peer-reviewed articles from 1990 to 2024, comparing SLT and BLT across several parameters, including indications for transplantation, overall survival, pulmonary hypertension, complications, chronic rejection, functional status, and [...]

1133 11968

Open Access Original Research

Unraveling Bioactive Constituents Isolated from Knema hookeriana Warb. as Potential Acetylcholinesterase Inhibitors

Received: 05 March 2025;  Published: 27 April 2025;  doi: 10.21926/obm.neurobiol.2502286

Abstract

The Myristicaceae family, particularly the Knema genus, is renowned for its diverse bioactive compounds, including lignans, flavonoids, and phenolics. This study explores the phytochemical profile of Knema hookeriana Warb. leaves and evaluates their potential as acetylcholinesterase (AChE) inhibitors. Phytochemical extraction was performed using a cold maceration method with a polarity-gradient solvent system (hexane, ethyl acetate, and methanol). The isolated compounds were purified through chromatographic techniq [...]

1143 6218

Open Access Review

The Roles of IL-6, IL-8, and TNF-α in Pediatric Immune Defense and Infection Severity

Received: 12 December 2024;  Published: 23 April 2025;  doi: 10.21926/obm.genet.2502293

Abstract

Cytokines are pivotal regulators of immune responses. They are critical in mediating inflammation, recruiting immune cells, and driving pathogen clearance. Among these, interleukin-6 (IL-6), interleukin-8 (IL-8), and tumor necrosis factor-alpha (TNF-α) stand out as key players in pediatric immunity, as they exhibit unique expression patterns that reflect the dynamic nature of the developing immune system. This review explores the dual roles of these cytokines in orchestrating immune defense and their potential as d [...]

1461 12870

Open Access Interview

An Interview with Prof. Corrado I. Angelini

Received: 17 April 2025;  Published: 22 April 2025;  doi: 10.21926/rpn.2502008

763 4118

Open Access Review

Assessment of Water Balance Dynamics and Resource Stress in the Gaza Strip, Palestine

Received: 23 December 2024;  Published: 21 April 2025;  doi: 10.21926/jept.2502007

Abstract

Water scarcity is one of the most pressing global challenges, particularly in arid and semi-arid regions. In this context, the Gaza Strip, where groundwater is the only available natural water resource, faces severe water stress due to overexploitation and drought conditions. This study aimed to review the recent water budget for the Gaza Strip by collecting data for the years (2021-2022) which was analyzed, discussed, and compared with other studies. The results showed a sharp deterioration in the Gaza Strip in te [...]

1422 8267

Open Access Review

Mental Health Disorders Following Exposure to Endocrine Disruptor Chemicals

Received: 27 October 2024;  Published: 18 April 2025;  doi: 10.21926/obm.neurobiol.2502285

Abstract

There is growing scientific concern regarding how endocrine-disrupting chemicals (EDCs) impact central nervous system (CNS) disorders. Both anecdotal and preclinical studies suggest a link between EDC exposure and major depressive disorder (MDD), potentially leading to neurodegenerative outcomes. EDCs primarily exhibit their biological effects by interacting with hormone receptors. Nonetheless, there is scientific evidence pointing to dysfunction in the hypothalamic-pituitary-gonadal-adrenal axis, which is linked t [...]

1276 8705

Open Access Original Research

Utilizing Machine Learning to Map Aquatic Weed Yields for Biochar Production: A Case Study in the Bangweulu Wetlands, Zambia

Received: 26 September 2024;  Published: 17 April 2025;  doi: 10.21926/aeer.2502020

Abstract

Aquatic weeds present significant ecological and socio-economic challenges in the Bangweulu Wetlands of northern Zambia, where their proliferation disrupts aquatic ecosystems, impedes fishing activities, and affects local livelihoods. Despite these challenges, aquatic weeds also offer a unique opportunity for sustainable biochar production, a clean alternative cooking fuel that can alleviate pressure on diminishing forest resources. This study explores the application of machine learning (ML) techniques to estimate [...]

1365 6042

Open Access Review

Rejuvenating the Skin: The Role of Macro and Microalgae in Preventing Aging

Received: 26 January 2025;  Published: 17 April 2025;  doi: 10.21926/obm.geriatr.2502308

Abstract

The increasing consumer demand for cosmetic products has led to the widespread use of synthetic substances, which are inexpensive and readily available but can sometimes harm the skin and body. Examples include hydroxybenzoic acid esters (parabens) and phthalates, which are considered endocrine disruptors, and synthetic fragrances that may cause irritation or allergies. Consequently, there has been a shift in consumer preferences towards natural cosmetic products. In response to this demand and the expanding market [...]

1165 9430

Open Access Review

Updates in Liver Transplantation for Alcohol-Related Liver Disease

Received: 30 November 2024;  Published: 17 April 2025;  doi: 10.21926/obm.transplant.2502247

Abstract

The prevalence of alcohol use disorder (AUD) and alcohol-related liver disease (ALD) has increased in the last two decades. ALD is currently the most common indication for both waitlist additions and liver transplant (LT) in the United States, including alcohol-associated cirrhosis, alcohol-associated hepatitis (AH), and acute-on-chronic liver failure (ACLF). ALD also has a significant global disease burden. LT in ALD is a complex paradigm that poses both medical and ethical challenges, requiring a multidisciplinar [...]

1329 10043

Open Access Original Research

Hydrochemical Characteristics of Groundwater in the Mutoshi Deposit Environment, Kolwezi (Lualaba, DR Congo)

Received: 19 September 2024;  Published: 16 April 2025;  doi: 10.21926/aeer.2502019

Abstract

This study examines the hydrochemical characteristics of groundwater in the Mutoshi mining environment in Kolwezi, Democratic Republic of Congo, addressing gaps in understanding the impact of mining on water quality. Despite the DRC's vast water resources, only 26% of the urban population has access to safe drinking water, with the Mutoshi aquifer, providing over a quarter of Kolwezi's drinking water, facing deterioration due to underlying copper and cobalt-rich geological formations. Groundwater and geological sam [...]

1415 8680

Open Access Research Article

Mental Health Service Users' Experiences of Receiving Ear Acupuncture as a Complement in Psychiatric Care in ICELAND – A Qualitative and Quantitative Pilot Study

Received: 19 December 2024;  Published: 15 April 2025;  doi: 10.21926/obm.icm.2502018

Abstract

Depression, insomnia, cravings, and anxiety are significant and often long-lasting health problems. As medication has limited effect and often side effects, complementary methods such as ear acupuncture are used in mental health care. To describe mental health care users' experiences of ear acupuncture, including ratings of sleep, anxiety, depression, stress, pain, and cravings. This mixed methods study included in- and outpatients at a mental health rehabilitation service in Iceland. Standardized ear acupuncture ( [...]

1140 7960

Open Access Review

Neurotoxicity Following Exposure to Chlorpyrifos

Received: 14 January 2025;  Published: 15 April 2025;  doi: 10.21926/obm.neurobiol.2502284

Abstract

Neurotoxicity occurs when exposure to a biological, chemical, or physical agent, especially a neurotoxin, alters the normal activity of the nervous system in a way that results in permanent or reversible damage to neurons and nerve tissue and disrupts the functioning of the brain and nervous system. Chlorpyrifos is a broad-spectrum organophosphorus insecticide that has been used worldwide for more than 50 years and can damage the nervous system of insects by creating neurotoxicity. Epidemiological studies show that [...]

3490 13986

Open Access Review

Agrobacterium-Mediated Genome Modification for Improvement of Oil Palm Planting Materials

Received: 18 December 2024;  Published: 15 April 2025;  doi: 10.21926/obm.genet.2502292

Abstract

Oil palm is the most productive vegetable oil crop compared to other oil-bearing crops because it produces the highest oil yield per hectare. Palm oil is very versatile since it is used for producing food and beverages, personal care and cosmetics, cleaning products, biofuel, and bioenergy. To cater to the increasing demand in the global palm oil market, much research has been done to improve the oil's yield and modify its quality in addition to the oil palm height through breeding. Due to its long breeding cyc [...]

2249 16775

Open Access Review

Advancing Single-Cell Detection of Senescent Cells: Laboratory Methods and Clinical Applications

Received: 30 November 2024;  Published: 14 April 2025;  doi: 10.21926/obm.geriatr.2502307

Abstract

Cellular senescence (aging) is a physiological process that plays a role in tissue remodeling, wound healing, and embryogenesis. Prolonged senescence of cells can have detrimental effects and trigger a secretory phenotype (SASP, senescence-associated secretory phenotype), degenerative disorders, cancer, and age-related diseases. Suitable biomarkers and a range of different laboratory methods are used to investigate these complex relationships in vitro and in vivo. Since a universal biomarker for cell senescence has [...]

1603 11371

Open Access Case Report

Exploring the Genetic Landscape of Knobloch Syndrome: Novel Variant Identification and Literature Review

Received: 22 November 2024;  Published: 14 April 2025;  doi: 10.21926/obm.genet.2502291

Abstract

Knobloch Syndrome (KS) is a rare genetic disorder characterized by ocular abnormalities and central nervous system (CNS) defects, which are attributed to collagenopathy. The primary gene implicated in KS is COL18A1, which encodes the alpha chain of type XVIII collagen. This type of collagen functions as a proteoglycan, predominantly located in the basement membrane of human tissues. This study examined an Iranian female presenting with symptoms of horizontal nystagmus, strabismus, and suspected vision loss, with a [...]

1111 6341

Open Access Interview

An Interview with Prof. Dr. Pedro Fonte

Received: 07 April 2025;  Published: 11 April 2025;  doi: 10.21926/rpse.2502008

881 4272

Open Access Original Research

Experiences and Support Needs of Informal Caregivers in Managing Behavioral Symptom of Dementia

Received: 03 October 2024;  Published: 10 April 2025;  doi: 10.21926/obm.geriatr.2502306

Abstract

About 90% of people living with Alzheimer's disease and related dementias experience behavioral and psychological symptoms during the course of the disorder. Although extensive research exists on the roles of informal caregivers in dementia care, their abilities to manage behavioral symptoms and the resources they turn to for support remain understudied. This phenomenological study explored informal caregivers' experience, knowledge sources, and self-initiated strategies for managing behavioral symptoms of dementia [...]

1047 5220

Open Access Original Research

Assessment of the Main Elements for a Healthcare Waste Management System Using Analytical Hierarchical Process

Received: 16 October 2024;  Published: 10 April 2025;  doi: 10.21926/aeer.2502018

Abstract

When addressing Healthcare Waste Management (HCWM), numerous factors play a crucial role in ensuring its safety and environmentally responsible handling within institutional processes. Recognizing this imperative, this study employed the Analytical Hierarchical Process (AHP) methodology to establish a comprehensive assessment of 10 primary criteria and 66 sub-criteria concerning the governance and operational aspects of Healthcare Waste Management. This evaluation was based on the insights of 14 specialists in the [...]

1414 7573

Open Access Review

Unraveling the Involvement of Serotonergic 5-Hydroxytryptamine Receptor-6 Activation in Chronic Pain: A Narrative Review

Received: 28 September 2024;  Published: 09 April 2025;  doi: 10.21926/obm.neurobiol.2502283

Abstract

Chronic pain is a significant and global healthcare issue that hugely implies the quality of life and productivity of the affected individuals. It is challenging to treat and thus necessitates a deeper understanding of its underlying pathomechanisms to develop targeted interventions. Serotonin is one of the essential neurotransmitters involved in the propagation of pain signals through both ascending and descending pathways, acting via various receptor subtypes, including the 5-hydroxytryptamine receptor-6 (5-HT6R) [...]

1430 6969

Open Access Case Report

When Immunity Falls Short: Meningoencephalitis Despite Vaccination - A Case Report

Received: 13 June 2024;  Published: 09 April 2025;  doi: 10.21926/obm.transplant.2502246

Abstract

Varicella-zoster virus (VZV) significantly impacts the central and peripheral nervous systems, particularly in immunocompromised individuals. This case report details a rare presentation of VZV meningoencephalitis in a 42-year-old woman with interstitial lung disease and connective tissue disease undergoing lung transplant evaluation who presented with a thunderclap headache and a new-onset seizure. Despite normal initial MRI findings, further investigation with PCR of the cerebrospinal fluid (CSF) revealed the pre [...]

928 4488

Open Access Review

The Crucial Role of Vitamin D in Regulating Gut Microbiota in Inflammatory Bowel Disease

Received: 17 November 2024;  Published: 08 April 2025;  doi: 10.21926/rpn.2502007

Abstract

In recent years, there has been an alarming increase in the incidence of inflammatory bowel disease (IBD), which includes both Crohn's disease (CD) and ulcerative colitis (UC), particularly in Western countries. This chronic condition is intricately linked to the composition and health of the gut microbiota (GM) — a complex community of microorganisms residing in the gastrointestinal (GI) tract. Despite extensive research, the underlying pathogenesis of IBD remains poorly understood, making it a wide area of invest [...]

1350 8983

Open Access Original Research

Household Exposure to Secondhand Cigarette Smoke during Pregnancy and Adverse Offspring Health Outcomes in The Gambia: A Cross-Sectional Study

Received: 31 August 2024;  Published: 08 April 2025;  doi: 10.21926/rpn.2502006

Abstract

The adverse effects of maternal passive smoking during pregnancy on offspring health remain understudied in sub-Saharan Africa, particularly in The Gambia, where smoke-free regulations are limited. To determine the prevalence of maternal passive smoking (MPS) during pregnancy and investigate its associations with adverse pregnancy outcomes and offspring health complications in The Gambia. A cross-sectional study was conducted in February 2023 among 401 mothers with children under 5 years in urban and rural regions [...]

1761 8829

Open Access Original Research

Sustainable Alternatives for Energy Generation and Food Production in Brazil

Received: 23 September 2024;  Published: 07 April 2025;  doi: 10.21926/aeer.2502017

Abstract

Urbanization driven by industrialization and population growth amplifies food consumption and reinforces the need for more fuels and energy. However, the expansion of biofuels can impose risks on long-term food security. This paper examines potential alternative crops for energy generation and food production, including those used by family farmers and their associations, to decentralize energy production and utilization as a crucial pillar of the global energy transition. Cassava, corn, and sugar beet are the chos [...]

1719 9989

Open Access Original Research

Teachers on Self-Care

Received: 19 November 2024;  Published: 07 April 2025;  doi: 10.21926/obm.icm.2502017

Abstract

Teachers face at-work risk factors including compassion fatigue, burnout, dealing with violence, and a teacher shortage. A review of the literature shows that self-care can have positive benefits that mitigate and help to buffer these at-work risk factors This study examines teachers’ stories of self-care. The data suggests that self-care is a positive practice for teachers professionally and personally.

1374 9629

Open Access Original Research

Moldavian Dragonhead Extract: A Natural Collagen-Booster to Target Skin Aging

Received: 09 December 2024;  Published: 03 April 2025;  doi: 10.21926/obm.geriatr.2502305

Abstract

The complex process of skin aging results in noticeable changes, including decreased collagen content, reduced elasticity, and decreased hydration. Interventions to preserve or restore collagen, a key structural protein, may help counteract these signs. The concept of "beauty from within” through nutritional supplements is of growing interest, particularly the use of plant-based alternatives to animal-derived or synthetic collagen. This study investigated the anti-aging potential of an extract from Moldavian dragon [...]

1328 11334

Open Access Case Report

Oral Features in Children with X-Linked Hypophosphatemic Rickets: An 8-Year Follow-Up Case Report

Received: 19 March 2024;  Published: 03 April 2025;  doi: 10.21926/obm.genet.2502290

Abstract

X-linked hypophosphatemic rickets (XLHR) is a hereditary metabolic disease caused by the loss of phosphate through the renal tubules into the urine and an associated decrease in serum calcium and potassium phosphate, resulting in bone and dental abnormalities. We report this case, aiming to describe, through an 8-year follow-up case report, the clinical approach adopted in managing dental features in both primary and permanent dentition in a child diagnosed with XLHR. The oral manifestations were mainly premature e [...]

846 4134

Open Access Concept Paper

Enhancing Biodiversity Education and Outreach for Conservation Awareness and Environmental Stewardship

Received: 15 August 2024;  Published: 02 April 2025;  doi: 10.21926/aeer.2502016

Abstract

Biodiversity—the rich variety of life on Earth—is essential for ecosystem stability and resilience, which, in turn, supports human well-being. However, human activities, such as habitat destruction, pollution, overexploitation, and climate change, are placing unprecedented pressures on global biodiversity, emphasizing the need for urgent conservation measures. In response, biodiversity education and outreach initiatives have become pivotal in fostering conservation awareness and action. This paper critically evalua [...]

2065 12733

Open Access Original Research

A Novel Approach to Carbon Monoxide Removal Using Transition Metal-Doped Boron Nitride Nanosensors for Environmental Sustainability

Received: 12 November 2024;  Published: 02 April 2025;  doi: 10.21926/jept.2502006

Abstract

Adsorption of toxic gas of CO molecules by using transition metals of X (X = Ti, V, Cr, Co, Cu, Zn)-doped boron nitride nanocage (B5N10_NC) has been studied by computational chemistry. Based on NQR analysis, X-doped on B5N10_NC has shown the lowest fluctuation in electric potential and the highest negative atomic charge, including 0.2331 (copper), 0.3112 (cobalt), 0.5883 (chromium), 0.6853 (zinc), 0.6893 (vanadium) and 0.7499 coulomb (titanium), respectively, have presented the most tendency for being the electron [...]

1054 4876

Open Access Original Research

Entropy and War, Toy Models

Received: 05 February 2025;  Published: 02 April 2025;  doi: 10.21926/rpse.2502007

Abstract

This study investigates the relationship between entropy and societal dynamics, with a particular focus on the origins and implications of war. By using entropy as a measure of uncertainty and inequality, the research examines societal stability through patterns of stratification and wealth distribution. Employing simplified models of various wealth distributions, the study explores their effects on social stratification and the potential for conflict. Drawing on historical and contemporary examples, it delves into [...]

1051 9850

Open Access Review

Poly ε-Caprolactone Scaffolds: Advancements in Bone Regeneration and Grafting

Received: 20 October 2024;  Published: 02 April 2025;  doi: 10.21926/obm.transplant.2502245

Abstract

In orthopedics and oncology, benign and malignant bone lesions pose significant clinical challenges. Malignant tumors, like osteosarcomas and multiple myeloma, pose substantial health dangers and can spread common and mostly non-life-threatening benign lesions, including non-sizing fibromas and unicameral bone cysts. Treatment plans for bone lesions may involve radiation, chemotherapy, and surgical excision, depending on their type. Combining stem cell research, bioactive materials, and advanced scaffold design, cu [...]

1205 9686

Open Access Review

Pregnancy Risk Factors in Cerebrovascular Disease

Received: 16 May 2024;  Published: 01 April 2025;  doi: 10.21926/obm.neurobiol.2502282

Abstract

Cerebrovascular diseases such as strokes and cerebral hemorrhages are important causes of death in the world, which increase during pregnancy due to physiological conditions. This study investigated risk factors such as diabetes mellitus, hypertension and other factors by searching in databases. After searching, 35 articles were reviewed based on the inclusion criteria. The inclusion criteria included articles from 2014-2024 related to the words "pregnancy" AND "cerebrovascular disease." The obtained results were e [...]

742 4437

Open Access Research Article

An Analysis of Thermal Comfort in a School’s Outdoor Space: A Case Study of a Typical School, Dubai, UAE

Received: 29 October 2024;  Published: 01 April 2025;  doi: 10.21926/aeer.2502015

Abstract

Outdoor school spaces are significant, as they provide great opportunities for outdoor exploration, leading to the overall enhancement of a student’s well-being. This paper analyzes the outdoor school spaces in Dubai to optimize them and ensure their thermal comfort. To achieve this aim, using a mixed methodology approach of survey, field observation, workshops and ENVI-met V5.3 software simulation, the existing outdoor spaces were analyzed and then enhanced using several proposed heat mitigation strategies. The im [...]

1429 11938

Open Access Review

Diagnosis of Infectious Diseases by CRISPR/Cas System

Received: 18 November 2024;  Published: 01 April 2025;  doi: 10.21926/obm.genet.2502289

Abstract

Since the initial discovery of the CRISPR system in bacteria as an adaptive immune system, a deeper understanding of CRISPR structure and function has made it possible to perform gene editing, gene therapy, and revolutionize the diagnostic field. One of the exciting applications of the CRISPR-Cas system is used as a tool for the rapid diagnosis of infectious diseases and their treatment and the prevention of infection spread among people. The CRISPR-based diagnostic system could be the next-generation standard beca [...]

1674 20561

Open Access Review

Simulation Software in the Design and AI-Driven Automation of All-Terrain Farm Vehicles and Implements for Precision Agriculture

Received: 26 August 2024;  Published: 01 April 2025;  doi: 10.21926/rpse.2502006

Abstract

Precision agriculture depends on the automation and mechanization of agricultural equipment and vehicles in a variety of terrains, which increases productivity and sustainability. This review presents a comparative analysis of significant simulation software used in designing and developing automated agricultural systems, emphasizing their methodologies and significance in advancing farm technology. Artificial intelligence (AI) and machine learning (ML) methods are modeled, optimized, and integrated using key techn [...]

3326 21110

Open Access Original Research

Identification of Soybean Components that Prevent the Entry of Influenza Virus

Received: 31 August 2024;  Published: 01 April 2025;  doi: 10.21926/rpn.2502005

Abstract

We have previously demonstrated the anti-influenza virus activity of a soybean extract, indicating the presence of compounds that prevent viral entry into cells. In this study, we sought to identify the compounds in hydrothermal extracts of soybean that blocked viral entrance and analyzed their mechanisms of action. Hot aqueous extracts of roasted soybeans were separated by reverse-phase chromatography on an octadecylsilyl C18 column, and the antiviral activity of individual fractions was measured during the viral [...]

1106 5194

Open Access Review

Cytomegalovirus Management in Solid Organ Transplant Recipients

Received: 11 November 2024;  Published: 01 April 2025;  doi: 10.21926/obm.transplant.2502244

Abstract

Cytomegalovirus (CMV) remains a significant cause of morbidity and mortality in solid organ transplant (SOT) recipients. Despite advancements in prophylaxis and antiviral therapy, CMV continues to pose clinical challenges in transplant medicine. This review provides a comprehensive overview of CMV, exploring its pathophysiology, epidemiology, and clinical presentation in SOT patients, in whom CMV infection can lead to direct organ involvement and systemic symptoms. Additionally, CMV has indirect effects, including [...]

1759 18226

Open Access Case Report

Forgiveness Therapy to Reduce Violent Behavior in Individuals with Schizophrenia: A Case Study

Received: 03 December 2024;  Published: 26 March 2025;  doi: 10.21926/obm.neurobiol.2501281

Abstract

This study aims to describe the application of forgiveness therapy as a psychosocial intervention for a schizophrenia patient with violent behavior. Mr. M, a 19-year-old male diagnosed with schizophrenia, exhibited psychotic symptoms, including auditory hallucinations, persecutory delusions, agitation, and aggression. He had a history of trauma due to physical violence from his brother. The patient was diagnosed with a risk for violence toward others. Forgiveness therapy was implemented over six sessions, each last [...]

1448 7333

Open Access Original Research

Investigating Interest in Cancer Predisposition Testing and Expanded Carrier Screening in Routine Gynecologic Care among Pregnancy Capable Individuals

Received: 28 May 2024;  Published: 25 March 2025;  doi: 10.21926/obm.genet.2501288

Abstract

The goal of this qualitative study was to explore pregnancy capable individuals’ perceptions of having cancer predisposition testing (CPT) and/or expanded carrier screening (ECS) during routine gynecologic care and how these perceptions differ across individuals. A thematic analysis was conducted based on qualitative data from 26 semi-structured interviews with women between 20 and 35 years of age at a single academic health center in the Mountain West of United States. The analysis indicated that participants’ int [...]

1271 4900

Open Access Original Research

Machine Learning Analysis of the Impact of Increasing the Minimum Wage on Income Inequality in Spain from 2001 to 2021

Received: 31 July 2024;  Published: 25 March 2025;  doi: 10.21926/rpse.2501005

Abstract

The main aim of this work is to analyze the impact of the National Minimum Wage (NMW) on wealth redistribution in Spain during the 2001-2021 period. This research addresses a fundamental question: Does increasing the minimum wage effectively reduce income inequality and contribute to a more equitable wealth distribution without negatively impacting overall economic growth and employment? Using a complete statistical census provided by the Spanish Tax Administration Agency, this study examines how the increase in th [...]

1604 7931

Open Access Original Research

Influence of Teachers’ Secondary Traumatic Symptoms on Their Burnout, Compassion Fatigue, and Intentions to Resign in Low Socioeconomic Status Schools

Received: 09 September 2024;  Published: 24 March 2025;  doi: 10.21926/obm.icm.2501016

Abstract

The current study explored the adverse outcomes of secondary traumatic symptoms experienced by secondary school teachers on their compassion fatigue, burnout, sense of satisfaction, and intention to resign from the teaching profession in low SES schools in the United States context. The study was inspired by Ludick and Figley’s Compassion Fatigue and Resilience model and Figley’s work on Compassion Fatigue. A non-experimental design was employed, and data were gathered from a random sample of 131 teache [...]

1678 9739

Open Access Research Article

Do We Care about Preschool Children's Leisure Time? Correlations between Anxiety Symptoms and Leisure Time Allocation. Results of a Cross-Sectional Study

Received: 06 January 2025;  Published: 24 March 2025;  doi: 10.21926/obm.neurobiol.2501280

Abstract

Children's leisure time in the Western world is changing compared to what it used to be in the previous decades. Children's involvement in organized activities and screen time use is increasing, while outdoor play, despite once being the main leisure time activity for children, is declining. Gray, Oliver and other contemporary theorists link this shift in children's lifestyles to an increase in the prevalence of anxiety disorders. This study aimed to determine whether allocating preschool children's [...]

1422 8022

Open Access Case Report

Pregnancy-Associated Spontaneous Coronary Artery Dissection: Anesthetic Considerations

Received: 29 August 2024;  Published: 20 March 2025;  doi: 10.21926/obm.transplant.2501243

Abstract

Spontaneous coronary artery dissection (SCAD) accounts for one-third of all peripartum myocardial infarction. Peripartum SCAD is associated with increased severity. We surmise that altered maternal cardiac physiology increases susceptibility to SCAD and warrants consideration when managing cardiac ischemia. One week after vaginal delivery, a 35-year-old woman with no known medical history developed multivessel SCAD and cardiogenic shock after attempted percutaneous coronary intervention, requiring rescue CABG and p [...]

1078 5534

Open Access Interview

An Interview with Prof. Takashiro Akitsu

Received: 19 March 2025;  Published: 19 March 2025;  doi: 10.21926/rpse.2501004

844 4039

Open Access Concept Paper

Improving Outcomes in Elderly Patients with Ovarian and Pancreatic Cancer through Multimodal Prehabilitation

Received: 19 August 2024;  Published: 19 March 2025;  doi: 10.21926/obm.geriatr.2501304

Abstract

Elderly patients with ovarian and pancreatic cancer frequently experience malnutrition and sarcopenia, which negatively impact treatment tolerance, functional outcomes, and survival. The increasing use of neoadjuvant chemotherapy in this population necessitates structured interventions to mitigate these challenges. While prehabilitation has shown promise in enhancing treatment tolerance and quality of life, its role during chemotherapy remains underexplored. This prospective study evaluates the feasibility and impa [...]

1115 6204

Open Access Original Research

Increasing the Omega-3 Index of Endurance Trained Adults: A Pilot Study Comparing Microencapsulated Algae to Fish Powders Provided as Chewable Tablets

Received: 12 November 2024;  Published: 19 March 2025;  doi: 10.21926/rpn.2501004

Abstract

Long-chain omega-3 fatty acids (LCn-3PUFA), including eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), support heart function during exercise and recovery by incorporating into the cardiac cell membranes. Traditionally sourced from fish and fish oil, algae-derived LCn-3PUFA have become alternative in supplemental forms. This study evaluated whether 12 weeks supplementation of a microencapsulated algal oil, delivered as chewable tablets, would perform equivalently to fish-derived LCn-3PUFA in boosting the [...]

1935 26784

Open Access Review

Functional Prognosis of Spinal Cord Injury Due to Spinal Tuberculosis

Received: 03 October 2024;  Published: 18 March 2025;  doi: 10.21926/obm.neurobiol.2501279

Abstract

Spinal tuberculosis (TB), an extrapulmonary manifestation of TB, primarily involves one or multiple vertebrae, with a high prevalence at the thoracolumbar region, which can compromise spinal cord integrity and result in severe sequelae such as paraplegia, bladder and bowel dysfunction, and mobility limitation. This study aimed to review medical, surgical, and rehabilitation management, clinical outcomes, and prognostic factors of spinal TB with spinal cord injury (SCI). Research was conducted utilizing databases su [...]

1521 10124

Open Access Original Research

A Pilot Study of a School-Based Yoga and Mindfulness Program for Girls

Received: 15 August 2024;  Published: 18 March 2025;  doi: 10.21926/obm.icm.2501015

Abstract

Schools have made commendable efforts to incorporate yoga and mindfulness programs to address the wellbeing of students; however, research on the efficacy of school-based yoga and mindfulness programs is still in its infancy, particularly with school-aged students at risk of developing externalizing disorders. Much of the research has also focused on evaluating interventions implemented by researchers, rather than evaluating those implemented by the school and its staff. The aim of this pilot study was to evaluate [...]

1903 11601

Open Access Review

The Independence Principle - A Neglected Feature of the Hodgkin Huxley Legacy

Received: 19 May 2024;  Published: 17 March 2025;  doi: 10.21926/obm.neurobiol.2501278

Abstract

The legacy of Hodgkin and Huxley rests on their squid giant axon studies, which were summarised in an empirical model of impressive predictive power that successfully quantified the permeability changes of excitable membranes and accurately reconstructed the action potential. Hodgkin and Huxley applied the independence principle to their experimental data in order to reveal potential mechanism(s) of trans-membrane ion movements. This was motivated by their lack of information on the manner in which ions crossed the [...]

1024 4956

Open Access Review

Neurotoxicity Following Exposure to Micro and Nanoplastics

Received: 13 December 2024;  Published: 16 March 2025;  doi: 10.21926/obm.neurobiol.2501277

Abstract

The pervasive presence and enduring existence of micro and nanoplastics in the environment render their exposure to humans and aquatic creatures unavoidable. Research indicates these tiny plastic particles can be taken in by aquatic beings and mammals. Once within the body, micro and nanoplastics have the capability to infiltrate the brain, although the level of penetration and the subsequent neurotoxic effects are not fully explored. Previous studies indicate that metal (oxide) nanoparticles can enter the brain an [...]

3857 21636

Open Access Original Research

A Systems Biology Approach to Understanding Delirium Pathophysiology and Identifying Natural Compounds for Potential Therapeutic Purposes

Received: 30 October 2024;  Published: 14 March 2025;  doi: 10.21926/obm.neurobiol.2501276

Abstract

Delirium is an acute neurocognitive disorder marked by disruptions in attention, cognition, and awareness, particularly prevalent among older and critically ill patients. This study applies a systems biology framework to dissect the molecular underpinnings of delirium and evaluate natural compounds for potential therapeutic roles. Through bioinformatics analyses, key biomarkers related to delirium, including IL6, AKT1, JUN, APP, and PPARGC1A, were identified, implicating pathways tied to neuroinflammation, oxidativ [...]

1445 7268

Open Access Original Research

How Viniyoga Supports Health and Healing

Received: 17 January 2025;  Published: 14 March 2025;  doi: 10.21926/obm.icm.2501014

Abstract

In this qualitative study, the impact of therapeutic Viniyoga on health and healing was explored from the perspective of 14 Viniyoga therapists who were interviewed on their perceptions of how yoga therapy contributes to the health and healing of their clients. A philosophical definition of Therapeutic Viniyoga was developed. Three themes related to health and healing from the perspective of Viniyoga therapists were identified using NVivo and Interpretative Phenomenological Analysis procedures: The definition of he [...]

997 6211

Open Access Original Research

Studying the Cognitive and Behavioural Dynamics of Psychopathy

Received: 04 December 2024;  Published: 14 March 2025;  doi: 10.21926/obm.neurobiol.2501275

Abstract

The relevance of studying the cognitive and behavioral dynamics of psychopathy lies in its importance for improving diagnosis, therapeutic interventions, and reducing crime, thereby contributing to public safety. This study aimed to investigate how cognitive and behavioral mechanisms influence psychopathy. A combination of methods was employed, including the Levenson Self-Report Psychopathy Scale, semi-structured interviews, and the analysis of non-verbal reactions. The sample consisted of eight participants (four [...]

1283 15688

Open Access Review

Review of Heterotopic Heart Transplantation Models in Rats

Received: 21 October 2024;  Published: 14 March 2025;  doi: 10.21926/obm.transplant.2501242

Abstract

Heterotopic heart transplantation (HHT) in rats is a valuable tool for cardiac transplantation research. While abdominal HHT has been established in rats for nearly 90 years, novel approaches involving cervical and femoral techniques have also been explored. The abdominal HHT model, despite its long history, is technically demanding and has a steep learning curve. In contrast, the cervical HHT model enables surgeons with more basic microsurgical skills to achieve competency more quickly while producing comparable o [...]

1270 5784

Open Access Review

Allogeneic Stem Cell Transplantation: Current Status and Future Directions

Received: 03 August 2024;  Published: 12 March 2025;  doi: 10.21926/obm.transplant.2501241

Abstract

Allogeneic stem cell transplantation (allo-SCT) improves the treatment of hematopoietic cancer and non-malignant disease. In this case, stem cells from a genetically similar but not identical donor may stimulate immune-mediated tumor cell destruction. Allogeneic stem cell transplantation, or allo-SCT, has significantly extended the life expectancy of numerous people. Nevertheless, complications such as infections, graft-versus-host disease (GVHD), and recurrence continue. This paper provides a thorough analysis of [...]

1344 11614

Open Access Original Research

Impacts of Carbon Capture and Storage (CCS) Technology on the Sustainability of Coal-Based Power Generation Pathways

Received: 16 November 2024;  Published: 10 March 2025;  doi: 10.21926/rpse.2501003

Abstract

Carbon capture and storage (CCS) technology mitigates greenhouse gas (GHG) emissions. However, comprehensive studies assessing the sustainability of coal-based power generation (CBPG) with CCS remain limited. This study focuses on developing comparative sustainability indicators across the entire life cycle of CBPG integrated with CCS technology. Sixty-six pathways were analyzed after establishing five sustainability indicators for each. These indicators were standardized per megawatt-hour (MWh) of energy, encompas [...]

1545 7601

Open Access Original Research

A Pilot Study Testing the Clinical Congruency of Healthcare Providers to Use a Clinical Decision Support Tool to Assess Falls in Older Adults

Received: 30 January 2024;  Published: 10 March 2025;  doi: 10.21926/obm.geriatr.2501303

Abstract

This research sought to determine feasibility for RNs to use the Post Fall Index™ (PFI) and to determine if an RN could identify underlying causal event factors for falls, would it be congruent with other providers (advanced practice nurse [APN], physician [MD])? PFI data from 23 falling residents of a nursing home were compiled into clinical vignettes and reviewed by experts for underlying causal event factors/fall sub-types. RNs used the PFI for one month in practice. The RN generated the most diagnoses; pe [...]

778 3658

Open Access Research Article

Design and Management of Renewable Energy Systems for Isolated Communities with No Grid Connection

Received: 10 October 2024;  Published: 07 March 2025;  doi: 10.21926/jept.2501005

Abstract

The growing demand for energy and the need to reduce dependence on non-renewable sources have driven the research and application of sustainable technologies. In this context, an integrated solution that combines distributed energy generation from renewable sources, such as wind and hydro, with efficient management of household energy consumption is proposed. This study focuses on the hybrid renewable energy system simulation analysis designed to meet the demand of an off-grid household in a self-consumption mode. [...]

1322 6830

Open Access Original Research

Design and Simulation of Computational Models of Hybrid Scaffolds Representative of Subchondral Bone and Hyaline Cartilage

Received: 22 August 2024;  Published: 07 March 2025;  doi: 10.21926/obm.transplant.2501240

Abstract

Tissue engineering offers alternatives when it comes to health problems such as trauma or pathologies. One of them is the scaffolds, which provide a favorable architecture, mechanics, and biocompatibility for the fixation of cells. Therefore, the following research aims to design and simulate scaffolds with mixed geometric structures to create a hybrid architecture for osseointegration while maintaining structural properties similar to subchondral bone and hyaline cartilage. Three scaffolds were designed for this p [...]

819 4500

Open Access Original Research

Computer-Aided Study on Metal Complexes with Benzohydrazide Schiff Base as Potential Bacterial and Fungi Inhibitors

Received: 22 October 2024;  Published: 06 March 2025;  doi: 10.21926/rpse.2501002

Abstract

The biochemical properties of metal complexes containing benzo hydrazide Schiff base have been reported by numerous researchers worldwide in various ways. In this work, the evaluation of biochemical roles of the metal complexes with benzo hydrazide Schiff base activity as anti-gram positive and gram-negative bacteria, as well as antifungal agents, were observed. The use of various techniques, including the induced fit docking methodology, the density functional theory method, and pharmacokinetics investigations wit [...]

1300 5178

Open Access Original Research

Soil Treatment from Hazardous Particles Using Designed Nanosensors: A Physical and Chemical Analysis

Received: 11 November 2024;  Published: 06 March 2025;  doi: 10.21926/cr.2501003

Abstract

Being critical to achieving Sustainable Development Goals (SDGs) of the United Nations, strengthening understanding of the properties and processes of soil at national and regional scales is imperative. The target of this research is removing transition metals of Cr, Mn, Fe, Zn, W, Cd from soil due to nanomaterial-based boron nitride nanocage (B5N10-nc). The electromagnetic and thermodynamic attributes of toxic transition metals trapped in B5N10-nc were depicted by materials modeling. It has been studied the behavi [...]

1328 5583

Open Access Original Research

A Pilot Double-Blind Randomised Sham-Controlled Trial of Paraesthesia-Free Burst Waveform Spinal Cord Stimulation in a Small Case Series of Patients with Chronic Spinal or Limb Pain

Received: 24 November 2024;  Published: 05 March 2025;  doi: 10.21926/obm.neurobiol.2501274

Abstract

The aim of this study was to identify methodological issues that might influence comparison of burst versus sham spinal cord stimulation for treating chronic pain. Six patients with an implanted BurstDR spinal cord stimulator were assessed double-blind during eight 3-to-4-day ON or OFF cycles over a 28-day period. The stimulator was switched off during two randomly selected cycles. Pain intensity was the primary outcome, and secondary outcomes included analgesic consumption, activity estimation and sleep quality. T [...]

753 4131

Open Access Original Research

Exploring Farmers’ Motivators and Barriers to Adopting Stress Management Behaviors

Received: 30 September 2024;  Published: 05 March 2025;  doi: 10.21926/obm.icm.2501013

Abstract

Farmers experience high levels of stress, with negative sequelae including physical illness, depression, anxiety, and suicide. Despite this, farmers are often reluctant to adopt stress management behaviors. This study collected survey data on motivators and barriers to stress management behavior change among farmers from 162 participants at a regional fruit and vegetable growers’ conference. Survey findings were analyzed using the Health Beliefs Model (HBM) as an organizing framework, calculating the frequency of s [...]

1061 4810

Open Access Case Report

Therapeutic Use of Auto-Induced Cognitive Trance in a Chronic Pain Setting: A Case Study Using Mixed Methodology

Received: 14 August 2024;  Published: 05 March 2025;  doi: 10.21926/obm.icm.2501012

Abstract

Auto-induced cognitive trance (AICT) is a method for voluntarily entering modified state of consciousness. The therapeutic implications of AICT are still unknown. Since complementary approaches based on modified states of consciousness are recognized to be beneficial for patients suffering from chronic pain (e.g., hypnosis, meditation), we here present the first case report of a 68-year-old man with a long history of chronic pain linked to an open Spina Bifida L4-L5, who used AICT to improve his health condition. S [...]

1424 7939

Open Access Original Research

Parenting Behavior and Early Childhood Mental Health: Cortisol Awakening Response as a Moderator of Child Internalizing and Externalizing

Received: 02 September 2024;  Published: 04 March 2025;  doi: 10.21926/obm.icm.2501011

Abstract

Certain observable parenting behaviors contribute to the risk of children developing internalizing and externalizing problems. Yet parenting behaviors do not affect all children uniformly and effects may depend on identifiable child characteristics. One factor is a child’s biological sensitivity to the caregiving environment, an indicator of which is a stress hormone, cortisol. This longitudinal study examines two dimensions of observable parenting behaviors, responsive and rejecting/harsh. These parenting behavior [...]

1504 5224

Open Access Review

The Role of Pulmonary Rehabilitation in Lung Transplantation for Cystic Fibrosis

Received: 11 December 2024;  Published: 03 March 2025;  doi: 10.21926/obm.transplant.2501239

Abstract

Cystic fibrosis (CF) is a genetic disorder that significantly impacts respiratory function, leading to progressive lung damage and ultimately respiratory failure. Lung transplantation (LTx) is a critical intervention for CF patients with end-stage lung disease, offering improved survival and quality of life. Pulmonary rehabilitation (PR) plays a pivotal role both preoperatively and postoperatively in optimizing outcomes for LTx candidates and recipients. Pre-transplant PR interventions, including exercise programs, [...]

1300 8132

Open Access Original Research

Comparative Study on Mental Health Parameters among Yoga and Non-Yoga Practitioners in Older Adults Amidst COVID-19 Pandemic

Received: 14 October 2024;  Published: 03 March 2025;  doi: 10.21926/obm.geriatr.2501302

Abstract

The COVID-19 pandemic has increased stress and disrupted routines affecting the psycho-social health of older adults, a vulnerable section of the population. Yogic practices have shown the potential to reduce stress, inflammation, and psychological health among other benefits. Hence, we explored the benefits of regular yoga practice on specific key mental health attributes in older adults amidst the pandemic. Using a case-control design, older adults (n = 54) who had been regularly practising yoga for the past six [...]

887 5652

Open Access Research Article

Motivation to Cultivate Social Ties and Diurnal Cortisol: Testing the Mediating Effect of Social Embeddedness in Chinese Older Adults

Received: 20 July 2024;  Published: 02 March 2025;  doi: 10.21926/obm.geriatr.2501300

Abstract

Based on a framework derived from theories of social integration and health, this study examined the relationships between motivation to cultivate social ties or network cultivation, and diurnal salivary cortisol in Chinese older adults. The main objective was to determine the behavioral mechanism that translated a higher motivation to cultivate social ties into healthier diurnal cortisol rhythms in 82 community-dwelling elders in Shanghai. Participants were provided four saliva samples immediately, 30 minutes, and [...]

937 3891

Open Access Original Research

Potential CRISPR-Cas9-based Antiviral Activity Against Hepatitis C Virus in Liver Cancer

Received: 04 July 2024;  Published: 28 February 2025;  doi: 10.21926/obm.genet.2501287

Abstract

Hepatitis C virus (HCV) is a primary global health concern, and though therapeutic options have improved, no very effective vaccine is available despite decades of research. The health and vitality of the organism are related to the result of homeostatic regulation of the internal environment. In contrast, it follows that disruption of homeostatic mechanisms leads to disease, particularly in liver cancer. Since HCV can rapidly mutate to evade the immune response, an effective HCV vaccine must rely on the identifica [...]

1290 5784

Open Access Research Article

Inheritance Studies of Root-Knot Nematode (Meloidogyne Species) Resistance in Tomato (Solanum Lycopersicum L.)

Received: 22 August 2024;  Published: 28 February 2025;  doi: 10.21926/obm.genet.2501286

Abstract

Plant-parasitic nematodes threaten tomato cultivation in Ghana, particularly the root-knot nematodes, causing substantial economic yield losses. However, these yield losses can be prevented through resistant varieties. This study aims to determine the type of gene action, heritability, heterosis and inbreeding depression for root-knot nematode resistance in tomato. A cross between CSIR/CRI-P005 (P1), an adapted variety with good yield but susceptible to root-knot nematode and VFNT (P2), which is resistant to root-k [...]

920 5381

Open Access Original Research

Comparison of Muscle Damage Markers and Myokines between Adult and Middle-Aged Marathon Runners

Received: 20 August 2024;  Published: 28 February 2025;  doi: 10.21926/obm.geriatr.2501301

Abstract

This study compared markers of muscle damage and myokines between adult and middle-aged runners before and after the marathon. Seventy-four male runners: 48 adults aged 30-44 years (AA group), and 26 middle-aged individuals aged 45-59 years (MA group) participated of the study. Blood samples were collected 24 hours before, immediately after, 24 hours and 72 hours after the marathon to measure skeletal and cardiac muscle damage markers (CK, LDH, troponin, and proBNP) and myokines (IL-6, IL-15, decorin, BDNF, GDF-15, [...]

1075 5433

Open Access Review

The Impact of Microbiota on Neurological Disorders: Mechanisms and Therapeutic Implications

Received: 06 November 2024;  Published: 28 February 2025;  doi: 10.21926/obm.neurobiol.2501273

Abstract

Interactions in the gut-brain crosstalk have led to the development of an entirely new concept: the "microbiota-gut-brain axis". Microbiota has gained considerable attention in relation to disorders of a more neurological nature, such as neurodevelopmental and neuropsychiatric illnesses like autism spectrum disorder, anxiety, and mood disorders. This review aims to summarize the recent trends and insights into the role and consequences of gut microbiota in brain health and pediatric neurological disorders. Dysbiosi [...]

1174 6140

Open Access Original Research

Development of a Life Cycle Sustainability Assessment Framework for Hemp-Based Building Materials in Australia

Received: 18 December 2024;  Published: 27 February 2025;  doi: 10.21926/aeer.2501014

Abstract

The construction industry, a cornerstone of global economic and social progress, is under increasing pressure to adopt sustainable practices due to its significant environmental footprint. Industrial hemp (Cannabis sativa L.) has gained attention as a renewable material for building applications, offering potential reductions in greenhouse gas emissions and resource consumption. However, its broader sustainability performance remains underexplored. This study develops a comprehensive Life Cycle Sustainability Asses [...]

1653 10698

Open Access Original Research

Management of Atrial Fibrillation after Kidney Transplant: Do We Need a New Metric?

Received: 06 December 2024;  Published: 27 February 2025;  doi: 10.21926/obm.transplant.2501238

Abstract

To evaluate the bleeding risk associated with anticoagulation (AC) in kidney transplant patients with post-operative atrial fibrillation (AF). We conducted a retrospective analysis of all adult kidney transplant recipients performed from October 2012 to February 2019 at our institution, the University of North Carolina at Chapel Hill, which accounted for 428 transplants. Variables assessed included AF occurrence, AC use, bleeding complications, stroke and bleeding risk stratification in AF (determined using CHA2DS2 [...]

793 5086

Open Access Review

Therapeutic Exercise Holds the Key to Improve Hand and Upper Limbs Dystonia Rehabilitation Programs: A Systematic Review

Received: 20 September 2024;  Published: 27 February 2025;  doi: 10.21926/obm.neurobiol.2501272

Abstract

Upper limb dystonia is a focal locomotion disorder affecting arm, forearm, and hand muscles, causing abnormal movements given by repeated, steady, and intercontinuous contractions. There are different types of dystonia and the multifaced nature of this pathology is challenging in the treatment management, leading to a worsening of affected patients’ life quality, mainly from a psychological point of view, but also from a functional perspective. This work examines the present literature regarding upper limb dystonia [...]

1071 7887

Open Access Review

Wind Turbines for Decarbonization and Energy Transition of Buildings and Urban Areas: A Review

Received: 14 August 2024;  Published: 26 February 2025;  doi: 10.21926/aeer.2501013

Abstract

The recent tendencies of drastic variations of environmental conditions, inundations, severe winds, and gusts besides heavy and unexpected long-duration rains showed the world an image of what could happen if emissions and global warming are not adequately controlled. Implementing new energy solutions as fast as possible is essential to cope with climate change, one of the biggest threats to our survival. These alarming signs intensified research and development efforts to replace fossil-based activities with renew [...]

1863 23629

Open Access Original Research

Integrating Telemonitoring in COPD Exacerbations Care: A Multinational Study Using the Alsayed System for Applied Medical-Care Improvement (ASAMI) Database

Received: 26 August 2024;  Published: 25 February 2025;  doi: 10.21926/obm.transplant.2501237

Abstract

This study was designed to investigate the ability of telemonitoring involving a secure electronic database called “Alsayed System for Applied Medical-Care Improvement” (ASAMI) to detect at least 95% of acute exacerbations of chronic obstructive pulmonary disease (AECOPD). This prospective observational study, which took place over 16 months in 2022-2023, was based at a medical center in Jordan. The study group participants were patients with COPD (from seven countries) with mixed levels of airflow limitation sever [...]

935 5706

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