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Open Access Review

Stem Cell-Derived Exosomes: Non-Coding RNA Cargos for Reprogramming the Tumor Immune Microenvironment

Received: 10 October 2025;  Published: 14 January 2026;  doi: 10.21926/obm.genet.2601325

Abstract

Stem cell-derived exosomes (SDEs) have emerged as revolutionary mediators in cancer immunotherapy, offering unprecedented potential to reprogram the immunosuppressive tumor immune microenvironment (TIME). These nano-sized extracellular vesicles, laden with non-coding RNAs (ncRNAs), serve as natural biocompatible carriers, capable of orchestrating immune cell dynamics, stromal remodeling, and tumor cell fate. Unlike their tumor-derived counterparts, which often propagate oncogenic signals, SDEs uniquely harbor immun [...]

810 2740

Open Access Review

Contribution of Solar Energy to Buildings’ Energy Demands: A Review

Received: 27 June 2025;  Published: 12 January 2026;  doi: 10.21926/aeer.2601002

Abstract

Buildings account for a significant portion of global energy consumption, estimated at 30-40%, and also contribute to greenhouse gas emissions. Energy consumption in a building is mainly thermal (natural gas) and electrical. This energy is usually used for heating water, cooking, illumination, ventilation and air conditioning, powering appliances, floor heating, and other activities. These activities were examined, and their substitution by solar-based energy sources was reviewed. To achieve this objective, an exte [...]

1254 3924

Open Access Original Research

Genetic Differentiation of Populations of Three Megalopolises by DNA Markers of the Y-Chromosome in Connection with the Problem of Developing Genetic Databases

Received: 04 June 2025;  Published: 12 January 2026;  doi: 10.21926/obm.genet.2601324

Abstract

The purpose of the study was to consider the distribution of Y-chromosome DNA markers in samples from the populations of the three largest megalopolises (Moscow, Saint Petersburg, and Novosibirsk) in the Russian Federation, in the context of developing genetic databases. The study aimed to compare the frequency profiles of 18 Y-chromosome STRs (Short tandem repeats) and the level of genetic differentiation. Based on FST estimates for the distribution of these 18 Y-chromosome STRs, the senior generations of Moscow a [...]

845 3139

Open Access Original Research

Valorization of Agro-Industrial Residues into Furfural via Catalytic Pyrolysis

Received: 15 October 2025;  Published: 12 January 2026;  doi: 10.21926/cr.2601002

Abstract

Pyrolysis is a promising technology for converting biomass waste into bio-oil, a liquid product that can serve as feedstock for fuels and high-value chemicals. In this study, bio-oil was produced via catalytic pyrolysis of pear pulp waste, a byproduct from juice and jam manufacturing, using a fixed-bed reactor. Initial non-catalytic experiments were conducted under nitrogen and vacuum atmospheres at temperatures ranging from 300 to 450°C for 15 minutes to evaluate the effect of temperature on bio-oil yield. The res [...]

752 2195

Open Access Original Research

An Exploration of the Experiences of Group Compassion Focused Therapy for Hospital Outpatients with Long-Term Mental Health Difficulties

Received: 07 April 2025;  Published: 12 January 2026;  doi: 10.21926/obm.icm.2601005

Abstract

There is now good evidence for the efficacy of Compassion Focused Therapy (CFT) for a variety of mental health difficulties. To deepen understanding of the processes underpinning CFT’s effectiveness, this service evaluation explored the experiences and reflections of individuals with long-term mental health difficulties who had previously received therapy and attended an 11-week CFT group. Ten clients were invited to the group; one withdrew before the group started because of work and personal commitments and anoth [...]

2396 4364

Open Access Research Article

Integrating Small-Scale Geothermal into a Mini-Grid to Improve Electricity Access in Nigeria

Received: 31 July 2025;  Published: 12 January 2026;  doi: 10.21926/jept.2601002

Abstract

Increasing local energy access in developing countries, particularly in off-grid regions where mini-grids are often overloaded, remains a critically underexplored area in energy transition. These regions often face significant technical and economic challenges, such as low generation capacity, high energy costs, limited energy access, and heavy reliance on diesel fuels. This study explores capacity expansion by integrating small-scale geothermal energy into such a mini-grid system to enhance the local energy supply [...]

1030 2854

Open Access Review

Genetic and Clinical Features of Tuberous Sclerosis Patients from the Republic of Bashkortostan

Received: 29 September 2025;  Published: 08 January 2026;  doi: 10.21926/obm.genet.2601323

Abstract

Tuberous sclerosis (TS) is one of the most common hereditary tumor syndromes, occurring with an average incidence of 1 in 9,000 newborns worldwide. The disease manifests itself through the development of tumors of the brain, kidneys, heart, lungs, and skin, along with characteristic depigmented spots. Tuberous sclerosis is caused by germline variants in the TSC1 (encoding hamartin) and TSC2 (encoding tuberin) genes. The hamartin-tuberin protein complex, together with the TBC1D7 molecule, inhibits the serine/threoni [...]

640 1829

Open Access Original Research

iRest™ Meditation Webinar Series Addresses Depression Symptoms in Older Adults

Received: 09 August 2025;  Published: 07 January 2026;  doi: 10.21926/obm.icm.2601004

Abstract

Older adults in the U.S. have higher rates of depression, stress, and chronic diseases. There is an urgent need for effective interventions to reduce depressive symptoms and enhance overall health and well-being. Meditation presents an appealing therapeutic option due to its cost-effectiveness, minimal risks, ease of use, and active patient involvement, with growing evidence indicating its effectiveness in reducing depressive symptoms. Online platforms may provide more accessible options for meditation intervention [...]

818 2659

Open Access Editorial

Acupuncture’s Effects on Intracranial Pressure: From Early Observations to Modern Insights

Received: 04 January 2026;  Published: 06 January 2026;  doi: 10.21926/obm.icm.2601003

Abstract

Understanding whether acupuncture can influence intracranial pressure (ICP) and cerebral hemodynamics remains a relevant and insufficiently explored question in contemporary neurovascular research. This editorial synthesizes early experimental observations with recent clinical and technological advances to reassess the cerebral effects of acupuncture from a modern perspective. Evidence from clinical studies indicates that acupuncture can alter cerebral blood flow velocity and regional perfusion, suggesting an inter [...]

633 1879

Open Access Short Review

The Role of Nitrogen-Containing Compounds in Chemical Neuroscience: Implications for Drug Development

Received: 03 May 2025;  Published: 04 January 2026;  doi: 10.21926/obm.neurobiol.2601318

Abstract

The study explores the crucial biological function of nitrogen in cyclic and acyclic structures with resonance potential, including tetrazoles, pyrroles, piperidines, and carbamates, within the realm of chemical neuroscience. It highlights the importance of these compounds for their biological properties and their ability to cross the blood-brain barrier (BBB) to reach the central nervous system (CNS). The study emphasizes the necessity for neurochemical drugs, like morphine, to effectively cross the BBB, as modifi [...]

812 2673

Open Access Editorial

Acknowledgment to Reviewers of Advances in Environmental and Engineering Research in 2025

Received: 04 January 2026;  Published: 04 January 2026;  doi: 10.21926/aeer.2601001

Abstract

The editors of Advances in Environmental and Engineering Research would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2025. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers can download a certificate of recognition directly from our submission system. Additionally, r [...]

730 1634

Open Access Editorial

Acknowledgment to Reviewers of Catalysis Research in 2025

Received: 03 January 2026;  Published: 04 January 2026;  doi: 10.21926/cr.2601001

Abstract

The editors of Catalysis Research would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2025. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers can download a certificate of recognition directly from our submission system. Additionally, reviewers can sign up to the Web [...]

829 1518

Open Access Editorial

Acknowledgment to Reviewers of OBM Genetics in 2025

Received: 04 January 2026;  Published: 04 January 2026;  doi: 10.21926/obm.genet.2601322

Abstract

The editors of OBM Genetics would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2025. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers can download a certificate of recognition directly from our submission system. Additionally, reviewers can sign up to the Web of Sci [...]

494 1242

Open Access Editorial

Acknowledgment to Reviewers of OBM Integrative and Complementary Medicine in 2025

Received: 04 January 2026;  Published: 04 January 2026;  doi: 10.21926/obm.icm.2601002

Abstract

The editors of OBM Integrative and Complementary Medicine would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2025. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers can download a certificate of recognition directly from our submission system. Additionally, reviewers [...]

553 1372

Open Access Editorial

Acknowledgment to Reviewers of Journal of Energy and Power Technology in 2025

Received: 04 January 2026;  Published: 04 January 2026;  doi: 10.21926/jept.2601001

Abstract

The editors of Journal of Energy and Power Technology would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2025. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers can download a certificate of recognition directly from our submission system. Additionally, reviewers can [...]

577 1345

Open Access Editorial

Acknowledgment to Reviewers of OBM Neurobiology in 2025

Received: 04 January 2026;  Published: 04 January 2026;  doi: 10.21926/obm.neurobiol.2601317

Abstract

The editors of OBM Neurobiology would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2025. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers can download a certificate of recognition directly from our submission system. Additionally, reviewers can sign up to the Web of [...]

541 1373

Open Access Editorial

Acknowledgment to Reviewers of Recent Progress in Materials in 2025

Received: 04 January 2026;  Published: 04 January 2026;  doi: 10.21926/rpm.2601001

Abstract

The editors of Recent Progress in Materials would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2025. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers can download a certificate of recognition directly from our submission system. Additionally, reviewers can sign up t [...]

496 1273

Open Access Editorial

Acknowledgment to Reviewers of Recent Progress in Nutrition in 2025

Received: 04 January 2026;  Published: 04 January 2026;  doi: 10.21926/rpn.2601001

Abstract

The editors of Recent Progress in Nutrition would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2025. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers can download a certificate of recognition directly from our submission system. Additionally, reviewers can sign up t [...]

527 1266

Open Access Editorial

Acknowledgment to Reviewers of OBM Geriatrics in 2025

Received: 03 January 2026;  Published: 04 January 2026;  doi: 10.21926/obm.geriatr.2601333

Abstract

The editors of OBM Geriatrics would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2025. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers can download a certificate of recognition directly from our submission system. Additionally, reviewers can sign up to the Web of S [...]

682 1392

Open Access Editorial

Acknowledgment to Reviewers of Recent Progress in Science and Engineering in 2025

Received: 03 January 2026;  Published: 04 January 2026;  doi: 10.21926/rpse.2601001

Abstract

The editors of Recent Progress in Science and Engineering would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2025. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers can download a certificate of recognition directly from our submission system. Additionally, reviewers [...]

478 1210

Open Access Editorial

Acknowledgment to Reviewers of OBM Transplantation in 2025

Received: 03 January 2026;  Published: 04 January 2026;  doi: 10.21926/obm.transplant.2601263

Abstract

The editors of OBM Transplantation would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2025. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers can download a certificate of recognition directly from our submission system. Additionally, reviewers can sign up to the Web [...]

503 1341

Open Access Original Research

A Frequency Analysis of the Professional Quality of Life of NeuroAffective Relational Model (NARM) Therapists after NARM Training

Received: 25 July 2025;  Published: 04 January 2026;  doi: 10.21926/obm.icm.2601001

Abstract

Research shows that trauma therapists often experience secondary trauma, which can lead to secondary traumatic stress, compassion fatigue, and burnout. Trauma-informed care training has shown promise in enhancing practitioners' professional quality of life, particularly for those regularly exposed to trauma. To our knowledge, no prior studies have examined the training outcomes of NeuroAffective Relational Model (NARM) therapists on professional quality-of-life indicators. This cross-sectional observational study a [...]

724 2791

Open Access Original Research

Psychological Flexibility in Borderline Personality Disorder: A Comparative Study with Healthy Controls

Received: 09 March 2025;  Published: 31 December 2025;  doi: 10.21926/obm.neurobiol.2504316

Abstract

This study aimed to examine the psychological flexibility of individuals diagnosed with borderline personality disorder (BPD) compared to healthy controls. Psychological flexibility is a key construct related to mental health and adaptive functioning, and understanding its levels in BPD can provide insight into symptom severity and treatment outcomes. The study included 58 individuals diagnosed with BPD and 62 healthy volunteer controls, all meeting specific inclusion and exclusion criteria. Participants completed [...]

543 2236

Open Access Review

Pharmacological Strategies to Enhance Bone Graft Integration: Emerging Agents and Molecular Pathways

Received: 15 May 2025;  Published: 31 December 2025;  doi: 10.21926/obm.transplant.2504262

Abstract

Bone grafting remains a cornerstone technique in orthopedic and reconstructive surgery, yet achieving successful graft integration continues to pose significant challenges, particularly in conditions such as osteoporosis, diabetes mellitus, and large bone defects. Traditional graft materials such as autografts, allografts, xenografts, and synthetics, often encounter limitations including immune rejection, poor vascularization, and insufficient osteogenic support. Emerging pharmacological strategies have shown promi [...]

1884 4509

Open Access Review

Optimizing Donor Management Strategies for DCD Lung Procurement

Received: 30 June 2025;  Published: 30 December 2025;  doi: 10.21926/obm.transplant.2504261

Abstract

Donation after circulatory death (DCD) offers a vital strategy to expand the donor lung pool; however, DCD lungs are uniquely susceptible to warm ischemic injury during procurement. This chapter reviews evidence-based and emerging donor management strategies aimed at mitigating ischemic damage and optimizing the suitability of DCD lungs for transplantation, encompassing hemodynamic and ventilatory optimization, bronchoscopic clearance, targeted pharmacological interventions, and strategies to minimize transfusion r [...]

704 2559

Open Access Short Review

The Application of Next-Generation Sequencing in Leukemia

Received: 02 May 2025;  Published: 25 December 2025;  doi: 10.21926/obm.genet.2504321

Abstract

Leukemia is a heterogeneous group of hematologic malignancies characterized by the dysfunctional proliferation of white blood cells in the bone marrow. Genetic alterations are important risk factors for the development and progression of leukemia, and their detection is crucial. Although many genetic techniques, including karyotyping, fluorescence in situ hybridization (FISH), and polymerase chain reaction (PCR), have provided valuable information, they all have the limitation of incomplete genomic coverage. The ev [...]

725 2679

Open Access Editorial

Biochar and Circular Economy Approaches in Environmental Sustainability

Received: 21 December 2025;  Published: 24 December 2025;  doi: 10.21926/aeer.2504035

Abstract

The rising concerns of soil erosion, organic waste generation and global warming have shown the need to address them through multifaceted methods that transcend conventional linear models of resource utilization. Circular economy is a regenerative model that is anchored on caring about waste valorisation, resource effectiveness and environmental fortitude. In this paradigm, biochar has been developed as a multifunctional compound capable of integrating waste management, soil rehabilitation, climate control and rene [...]

987 2896

Open Access Original Research

Preparation and Properties of Frozen Yoghurt Made from Camel Milk Fortified with Dates and Banana Fruits

Received: 30 July 2025;  Published: 22 December 2025;  doi: 10.21926/rpn.2504026

Abstract

This study was conducted to process frozen yoghurt (FY) from camel milk (CM) flavored with either 5% or 8% banana (B) or dates (D). The mix of FY consists of stirred yoghurt, sugar, Gum Arabic, and banana (Musa lutea) or dates (Phoenix dactylifera). The mix was divided into 4 portions and then each mix was sub-derived into an ice-cream machine and then packed into plastic cups that were stored at -18°C for 5 weeks. The chemical composition and sensory evaluation were conducted weekly. The chemical composition of FY [...]

887 2593

Open Access Research Article

Correlation between the Storage Pattern of Spent Fuel Casks and the Neutron Multiplication Factor

Received: 21 April 2025;  Published: 19 December 2025;  doi: 10.21926/jept.2504018

Abstract

The effective neutron multiplication factor (keff) of a fissile system is a function of space and time f(x, y, z, t), where (x, y, z) are the coordinates of the reference point in space, and t is time. The evidence of the time-dependence of the neutron multiplication factor of a fissile system was published in 2017. The spatial dependence is as important as the time dependence, as interacting arrays of fissile material during storage can lead to an increase in the system (keff). Therefore, evaluation of how the sto [...]

669 2399

Open Access Original Research

Psychometric Properties of a Scale to Measure Family Inclusion in Mexican Adults

Received: 20 June 2025;  Published: 17 December 2025;  doi: 10.21926/obm.geriatr.2504332

Abstract

This study aimed to evaluate the psychometric properties of the Family Inclusion Scale (FIS) for administration to adults and older Mexican adults. To this end, a questionnaire was structured with scales to evaluate family inclusion, loneliness, and perceived stress; the last two scales were previously validated. The sample (n = 347) consisted of young university adults aged 20 to 24 years and their grandparents aged 60 years. The conceptual emphasis of the Family Inclusion Scale generated was the identification of [...]

583 1637

Open Access Review

Administration of the Effects of Wireless Electromagnetic Fields on Living Tissues in Sustainable Urban Ecosystems

Received: 07 October 2025;  Published: 17 December 2025;  doi: 10.21926/rpse.2504017

Abstract

A relevant objective of managing an electromagnetic (EM) device is to improve its expected results and reduce its undesirable side effects. In this context, this paper aims to evaluate the interest of the two One Health and Responsible Attitude methods in the daily practice of wireless transmission (or transfer) in EM energy devices. These approaches are respectively linked to device eco-design and optimization, as well as to the protection of biodiversity and ecosystems against device side effects related to EM fi [...]

822 2596

Open Access Original Research

Use of Complementary and Integrative Medicine Among Cancer Survivors in Exercise Rehabilitation: A Cross-sectional Analysis

Received: 18 September 2025;  Published: 12 December 2025;  doi: 10.21926/obm.icm.2504054

Abstract

Complementary and integrative medicine (CIM) is commonly used by cancer survivors; however, patterns of use among individuals engaged in structured exercise rehabilitation remain understudied. This cross-sectional survey examined CIM use among 157 cancer survivors enrolled in a structured exercise-based rehabilitation program. CIM modality use (dependent variable) was grouped into herbal supplements, mind-body practices, and manipulative and body-based categories and analyzed with demographic and clinical character [...]

731 2058

Open Access Review

Neurobiology of Cancer Pain: A Narrative Review

Received: 10 September 2025;  Published: 12 December 2025;  doi: 10.21926/obm.neurobiol.2504315

Abstract

Chronic cancer pain results from the complex interaction of nociceptive, neuropathic, and neuroimmune mechanisms, which vary according to tumor type, location, stage, and treatment history. Recent advances in cancer neuroscience have reframed pain as a dynamic manifestation of reciprocal tumor–nerve–immune interactions, rather than a mere consequence of tissue damage. In this model, malignant, stromal, and immune cells remodel nociceptive circuits at peripheral and central levels. This narrative review, conducted i [...]

1620 4847

Open Access Case Report

Diagnostic Challenges of Rothmund-Thomson Syndrome in Infancy: A Case Report from a Resource-Limited Setting

Received: 26 October 2025;  Published: 11 December 2025;  doi: 10.21926/obm.genet.2504320

Abstract

Rothmund-Thomson syndrome (RTS) is a rare autosomal recessive disorder characterized by early-onset poikiloderma and multisystem abnormalities. Diagnosis is often confirmed through genetic testing, but in many resource-limited settings, molecular studies are unavailable, necessitating reliance on clinical and histopathological evaluation. We report a 1-year-old boy referred for assessment of progressive pigmented skin lesions. The patient was referred by a pediatrician with febrile neutropenia, bicytopenia suspicio [...]

770 2201

Open Access Original Research

Advancing Marine Renewable Energy for Island Nations: Design and Development of a 20 kW Floating Kuroshio Turbine (FKT)

Received: 15 September 2025;  Published: 10 December 2025;  doi: 10.21926/jept.2504017

Abstract

Taiwan relies heavily on imported fossil fuels, with over 98% of its energy demand supplied by foreign sources, posing significant challenges to national energy security. To explore alternatives, this study investigates the potential of marine renewable energy by developing a 20 kW floating hydrokinetic turbine prototype designed for deployment in the Kuroshio Current. The research encompasses system design, model validation, and both tank and at-sea testing to evaluate hydrodynamic performance and power generation [...]

787 2598

Open Access Editorial

Acupuncture in Gynecology and Assisted Reproduction – A Short Evidence-Based Review

Received: 08 December 2025;  Published: 09 December 2025;  doi: 10.21926/obm.icm.2504053

Abstract

Acupuncture has become an increasingly relevant complementary modality in modern gynecology and assisted reproduction. Its uses include the management of menstrual disorders, menopausal symptoms, infertility, polycystic ovary syndrome (PCOS), endometriosis, and others. Scientific progress in neurophysiology, laser acupuncture, and biomedical imaging has enabled a deeper understanding of the central and peripheral mechanisms underlying acupuncture’s effects. This editorial summarizes current evidence regarding physi [...]

1361 5026

Open Access Original Research

Occurrence of Multidrug Resistant Escherichia coli & Escherichia coli O157:H7 in Raw Cow Milk from Dhaka, Bangladesh

Received: 01 May 2025;  Published: 09 December 2025;  doi: 10.21926/rpn.2504025

Abstract

Enteropathogenic strains of Escherichia coli, like the serotype O157:H7, can cause significant health issues if consumed. Milk and dairy products can serve as a reservoir for the bacteria. Dissemination of multidrug-resistant E. coli through dairy products can become a potential health hazard if consumed. The present study investigates the occurrence of multidrug-resistant E. coli O157:H7 in raw milk obtained from farms and markets around Dhaka, Bangladesh. A Total of 50 milk samples were collected in this study fr [...]

1021 3516

Open Access Review

The Relationship between Hereditary Predisposition and Epigenetic Mechanisms of Schizophrenia Development

Received: 17 August 2025;  Published: 08 December 2025;  doi: 10.21926/obm.neurobiol.2504314

Abstract

Schizophrenia is a multifactorial mental disorder associated with multiple SNPs in the human genome, located mainly outside the annotated protein-coding genes. These regions contain a large number of retroelements, which drive epigenetic regulation. Therefore, it is suggested that schizophrenia-associated SNPs exert their influence on the pathological functioning and activation of retroelements, which contribute to epigenetic imbalance in the brain with the development of pathological processes. A reflection of the [...]

757 2525

Open Access Original Research

Framework for the Secured Integration of Renewable Energy into Power Systems

Received: 11 June 2025;  Published: 05 December 2025;  doi: 10.21926/jept.2504016

Abstract

This research introduces a blockchain framework to improve security and transparency for the use of renewable energy in power systems. The framework utilizes a permissioned blockchain architecture and IoT-based real-time monitoring to ensure data integrity and confidentiality and support efficient peer-to-peer (P2P) energy trading. Compared with traditional centralized energy management systems, the proposed design increases transaction security by 35%, decreases verification wait times by 28%, and decreases the ri [...]

773 2566

Open Access Original Research

Environmental Risk Assessment of Antiretrovirals Consumed in Belo Horizonte, Brazil

Received: 09 June 2025;  Published: 04 December 2025;  doi: 10.21926/aeer.2504034

Abstract

The development and utilization of pharmaceuticals, notably antiretrovirals (ARVs), have significantly enhanced both human quality of life and life expectancy. Nevertheless, the excretion of these compounds into aquatic environments, often exacerbated by inadequate sanitation infrastructure, poses considerable risks to biota. This investigation evaluated the environmental impact of 14 ARVs consumed within the municipality of Belo Horizonte (BH), Brazil. The assessment employed the Environmental Risk Assessment (ERA [...]

985 2936

Open Access Original Research

GHG Emissions Management in Urban Areas by Interactive Road Traffic Control: Application of Artificial Intelligence

Received: 04 June 2025;  Published: 03 December 2025;  doi: 10.21926/aeer.2504033

Abstract

The rising pollution levels in congested urban areas pose a serious threat to human health. Many solutions have been proposed to control and reduce gas emissions from road traffic, with results that are not entirely satisfactory. The adoption of new techniques and methodologies for early detection of pollutant emissions may enable effective management and control of road traffic contamination. The proposed method introduces an interactive protocol that facilitates communication between the traffic control center an [...]

686 2721

Open Access Original Research

The Value of Camellia sinensis in the Management of Toxicity Induced by Cancer Treatments

Received: 17 June 2025;  Published: 02 December 2025;  doi: 10.21926/obm.icm.2504052

Abstract

While radiotherapy is one of the main treatments for head and neck cancer, adverse effects limit its effectiveness and affect patients' quality of life. Although various radioprotective substances have been proposed, comprehensive strategies are needed to modulate radiotoxicity. In this regard, compounds from green tea (Camellia sinensis), with antioxidant, anti-inflammatory, and antiproliferative properties, could be suitable for optimizing the radiotherapy relationship. A descriptive, prospective study was conduc [...]

544 1953

Open Access Original Research

Paranitrophenol and Organic Azo Dye Degradation: Catalytic Power of Terminalia Leaf Silver Nanoparticles

Received: 19 September 2025;  Published: 01 December 2025;  doi: 10.21926/cr.2504010

Abstract

Terminalia species is a widely available plant that can be used to synthesise silver nanoparticles (AgNPs) and harness their catalytic capacity. This experimental design will explore the potential of Terminalia AgNPs in contributing to the degradation process of toxic chemicals generated by industries such as textiles, food, and pharmaceuticals. This research uses four leaf varieties of Terminalia species—T. arjuna, T. bellirica, T. chebula, and T. catappa—to synthesize AgNPs, evaluate their optimal synthesis condi [...]

950 4459

Open Access Original Research

Effects of Trauma, Shame, and Self-Criticism on Hoarding: Comparative Data and Treatment Implications

Received: 31 January 2025;  Published: 01 December 2025;  doi: 10.21926/obm.icm.2504051

Abstract

Severe trauma has a significant impact on self-attitudes and emotions, such as self-criticism and shame, and psychological symptoms. This topic has been more well studied among populations with Trauma and Stress-Related Disorders, but examined to a lesser extent in other clinical populations where adverse life events and potentially traumatic events are highly prevalent, such as Hoarding Disorder. The current study examined trauma exposure, and the relationships between trauma, self-criticism, shame, and symptom se [...]

976 3121

Open Access Original Research

Technology to Help People with Blindness and Intellectual Disability Manage Indoor Travel: Anticipating and Bypassing Obstacles

Received: 18 August 2025;  Published: 27 November 2025;  doi: 10.21926/obm.neurobiol.2504313

Abstract

Recent work with people with blindness and intellectual disability assessed a technology-aided program intended to help eight participants travel indoor routes to reach relevant destinations. The technology included a smartphone, two barcode readers worn by the participants at their ankles, barcodes displayed at specific points of the travel routes, and a mini speaker. The technology ensured that participants received verbal instructions on how to proceed (e.g., take a left turn, cross from one side to the other of [...]

631 2355

Open Access Perspective

From Vision to Strategy: Expanding Metaversal Integrative Healthcare with DAOs and Blockchain Ecosystems

Received: 26 May 2025;  Published: 26 November 2025;  doi: 10.21926/obm.icm.2504050

Abstract

Legacy, profit-driven organizational structures often lack the adaptability, equity, and innovation required for the evolving complexities of contemporary patient-centered care. They can limit access, constrain options, impose financial burdens, and hinder optimized delivery. Here, we propose a new architecture for metaversal integrative healthcare using decentralized autonomous organizations (DAOs). Blockchain technology and smart contracts underpin equitable, transparent, and resilient health ecosystems beyond in [...]

691 3237

Open Access Original Research

Differential Expression of MiR-21 and MiR-19 in Biliary Atresia: Diagnostic Potential and Therapeutic Implications

Received: 24 May 2025;  Published: 26 November 2025;  doi: 10.21926/obm.genet.2504319

Abstract

Biliary atresia (BA), a severe pediatric liver disease of unknown etiology, causes neonatal jaundice, progressive cholestasis, and life-threatening liver fibrosis. Emerging evidence suggests microRNAs (miRNAs) – small non-coding RNAs that regulate gene expression by binding target mRNAs may play a role in BA pathogenesis. Circulating miRNAs have shown diagnostic potential for various diseases, prompting our investigation of miR-21 and miR-19 as potential biomarkers in BA. We conducted a case-control study comparing [...]

825 2424

Open Access Review

Risk Assessment in Clinical Histocompatibility Testing: Challenges, Strategies, and Future Directions

Received: 15 July 2025;  Published: 25 November 2025;  doi: 10.21926/obm.transplant.2504260

Abstract

Though the role of clinical histocompatibility testing is fundamental to successful transplant, systematic risk assessment and mitigation strategies remain underutilised in this domain. This review addresses risk identification, analysis, and control measures across the pre-analytical, analytical, and post-analytical phases of clinical histocompatibility testing, in line with international standards such as ISO 15189:2022. A structured, risk-based quality management system (QMS) is imperative for ensuring accurate [...]

875 2742

Open Access Commentary

Loneliness, Love and Their Connection: A Commentary

Received: 24 August 2025;  Published: 25 November 2025;  doi: 10.21926/obm.neurobiol.2504312

Abstract

A significant social stigma is associated with loneliness. The prevalence of social isolation, in the dawn of the 21st century points to the growing isolation in America. Lonely people who commonly display negative self-perceptions, show great difficulty to establish social ties, and that may be related to their personal inadequacies, or socially undesirable attributes. Lonely people suffer from a low social perception, painting them as less psychologically adjusted, and not very capable in relating to others. That [...]

799 2773

Open Access Original Research

Evaluation of Full Blood Count–Derived Inflammatory Indices (SII, SIRI, PIV, NLR) in Behçet’s Disease Patients and Healthy Controls

Received: 01 October 2025;  Published: 24 November 2025;  doi: 10.21926/obm.genet.2504318

Abstract

This study investigated three novel complete blood count–derived inflammatory biomarkers Systemic Immune-Inflammation Index (SII), Systemic Inflammation Response Index (SIRI), and Pan-Immune-Inflammation Value (PIV) and their relationship with clinical features of Behçet’s Disease (BD). Established markers, including neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and monocyte-to-lymphocyte ratio (MLR), were also analyzed. Seventy HLA-B51–positive BD patients and 114 HLA-B51–negative healt [...]

742 3151

Open Access Review

Episomal Vectors: Principle, Utility, and Application

Received: 31 August 2025;  Published: 24 November 2025;  doi: 10.21926/obm.genet.2504317

Abstract

An episomal vector is a plasmid- or virus-based vector that is present extrachromosomally in cells after transfection. Although it disappears during cell proliferation, it can exist in non-dividing cells, such as neuronal and muscular cells, and continues to express a gene of interest (GOI). Such episomal vectors are usually based on sequences from DNA viruses such as bovine papillomavirus 1 and Epstein-Barr virus. When cells are transfected with an episomal vector harboring a drug-resistance gene and subsequently [...]

1988 11598

Open Access Research Article

Opportunities, Dilemmas, and Limitations in Applying "Healthy Living" and "Aging in Place" in Designs for New Housing Concepts in Dutch Neighborhoods

Received: 23 March 2025;  Published: 19 November 2025;  doi: 10.21926/obm.geriatr.2504331

Abstract

This article explores the ongoing work associated with the masterclasses "Towards an Inclusive Living Environment." It critically examines the concept of healthy living for all and aging in place by studying neighborhoods within Dutch cities. The article argues that creating inclusive, healthy environments fosters well-being and promotes a lifestyle of health and autonomy for all. Next to literature studies, we worked with our students in different neighborhoods of The Hague, conducting ethnographic research. Throu [...]

921 4020

Open Access Research Article

Investigating Mental Health Literacy and Its Relationship with Addiction to Social Networks among Allied Medical Sciences Students

Received: 24 June 2025;  Published: 19 November 2025;  doi: 10.21926/obm.neurobiol.2504311

Abstract

The widespread use of social media among college students has become a significant concern due to its potential impact on mental health and addictive behaviors. Social media platforms, while offering numerous benefits, can also foster environments that contribute to addiction, depression, and anxiety. College students, in particular, are vulnerable to these effects due to their high levels of social media engagement and the pressures of academic life. Mental health literacy, which involves understanding and managin [...]

713 3080

Open Access Review

Biochemical Foundations of Emotion Regulation: Implications for Pharmacological and Psychological Interventions-A Narrative Review

Received: 02 May 2025;  Published: 19 November 2025;  doi: 10.21926/obm.neurobiol.2504310

Abstract

Emotion regulation (ER) involves processes by which individuals modulate the intensity, duration, and expression of emotional responses, and its dysregulation is associated with a broad spectrum of psychological disorders. While traditionally conceptualized within psychological frameworks, ER is increasingly recognized as biologically grounded, involving intricate interactions between neurochemical, hormonal, and metabolic systems. This narrative review aims to synthesize current evidence on biochemical substrates [...]

2293 9897

Open Access Editorial

The Role of Artificial Intelligence in Microplastic Pollution Studies and Management

Received: 16 November 2025;  Published: 19 November 2025;  doi: 10.21926/rpse.2504016

Abstract

Artificial intelligence (AI) is reshaping microplastic research by enabling faster, more accurate, and scalable detection, characterization, and modeling. Deep learning automates the identification and classification of microplastics from microscopy images, while machine learning accelerates the recognition of polymers from Raman and infrared spectra. AI-based clustering and segmentation improve the analysis of complex samples, and source-apportionment models learn morphological and chemical features to trace emiss [...]

3089 9913

Open Access Case Report

Nursing Care for a Patient with a Risk of Suicide Due to Depression Using the Solution-Focused Brief Therapy Approach: Case Study

Received: 11 September 2025;  Published: 17 November 2025;  doi: 10.21926/obm.neurobiol.2504309

Abstract

Adolescent depression is linked to suicidal ideation and attempts. Nurses are well-positioned to deliver brief, supportive interventions. Solution-Focused Brief Therapy (SFBT) emphasizes solutions and the activation of personal resources. To describe the feasibility and clinical utility of SFBT, delivered alongside pharmacotherapy, for reducing suicide risk in an adolescent with depression. Single-case report using a nursing process approach in a 17-year-old female inpatient with a major depressive episode and high [...]

731 4175

Open Access Original Research

Rapid Green Synthesis of Silver Nanoparticles and Alginate-Silver Nanocomposite Beads Using Mashmoom (Ocimum basilicum), a Bahraini Household Medicinal Herb

Received: 16 June 2025;  Published: 17 November 2025;  doi: 10.21926/rpm.2504017

Abstract

The study focuses on the rapid green synthesis of silver nanoparticles (AgNPs) and alginate-silver nanocomposite (Alg-AgNc) beads using sweet basil or Mashmoom (Ocimum basilicum), a common household medicinal herb in Bahrain. The aqueous extract of mashmoom was used as a reducing and stabilizing agent in the reduction of the precursor salt, silver nitrate, and formation of stable AgNPs. The Alg-AgNc beads were prepared by ionotropic gelation of sodium alginate-AgNPs solution in calcium chloride. A strong surface pl [...]

735 2551

Open Access Research Article

Sleep and Mood as Mechanisms Linking Trauma Exposure to Alcohol Use in South African First Responders: A Serial Mediation Analysis

Received: 15 June 2025;  Published: 14 November 2025;  doi: 10.21926/obm.neurobiol.2504308

Abstract

First responders are routinely exposed to traumatic events in the line of duty, placing them at heightened risk for adverse mental health outcomes, including substance use. This study investigated the psychological mechanisms linking trauma exposure to alcohol use, specifically examining the serial mediating roles of insomnia and depression. A sample of 429 first responders (309 police officers and 120 paramedics) from the Western Cape, South Africa, completed an online survey comprising the Life Events Checklist-5 [...]

739 2962

Open Access Original Research

Cultural Cells: A Circular Economy-Driven Blueprint for Creative Tourism and Regional Revitalization in Greece

Received: 11 June 2025;  Published: 11 November 2025;  doi: 10.21926/aeer.2504032

Abstract

This study proposes a novel creative tourism model integrating artistic creation with circular economy principles to foster regional revitalization in North Euboea, Greece. Employing a case study approach, it develops the concept of “Cultural Cells”—dedicated hubs for artists and art students specializing in painting and sculpture—designed to enhance tourism through immersive engagement. The methodology combines qualitative analysis of regional cultural and environmental assets with theoretical estimates of circula [...]

1270 5049

Open Access Original Research

Comparative Analysis of Healthcare Waste Legislation: Alignment and Discrepancies between Federal, State, and Municipal Regulations

Received: 02 July 2025;  Published: 11 November 2025;  doi: 10.21926/aeer.2504031

Abstract

The management of healthcare waste (HCW) presents a significant environmental and public health challenge, aggravated by gaps in current Brazilian federal regulations. This study provides a comprehensive analysis of specific state and municipal legislation on HCW, comparing it with ANVISA Resolution No. 222/2018 and CONAMA Resolution No. 358/2005 to ascertain whether local regulations enhance management practices and can act as supplementary instruments to federal guidelines. The methodology was structured into thr [...]

1722 8371

Open Access Editorial

Points of View on Peer Review and the Potential for AI-Assisted Review

Received: 09 November 2025;  Published: 11 November 2025;  doi: 10.21926/rpse.2504015

623 2018

Open Access Editorial

And the ICMART Science Award 2025, Presented at the World Congress on Medical Acupuncture, Goes to…

Received: 10 November 2025;  Published: 10 November 2025;  doi: 10.21926/obm.icm.2504049

Abstract

During this year’s World Congress on Medical Acupuncture, the ICMART (International Council of Medical Acupuncture and Related Techniques) Science Award 2025 was presented in recognition of excellence in research and innovation within the field of medical acupuncture. The award honored pioneering work on acupuncture and moxibustion in chronic fatigue syndrome (CFS), conducted in collaboration with the team at Hubei University of Chinese Medicine, Wuhan. The study, a randomized controlled trial (RCT), showed that ac [...]

889 4476

Open Access Review

Physio-Chemical and Molecular Characterization of Salinity Stress in Wheat: Mitigation Approaches and Future Perspectives

Received: 09 July 2025;  Published: 10 November 2025;  doi: 10.21926/obm.genet.2504316

Abstract

Wheat constitutes the backbone of global food supplies, and its production is directly linked to the food and nutritional security of the mounting population. Wheat is vulnerable to abiotic stresses like heat, salinity, and drought. These abiotic stresses tend to reduce the food security of the increasing population by reducing wheat production and nutritional quality. Among abiotic stresses, salinity stress (SS) has emerged as the most prevailing stress in modern high-input wheat farming systems, as it severely ha [...]

1286 5244

Open Access Research Article

The Nociceptive Glio-Neural Complex as a Histoanatomical Substrate of Acupuncture Meridians?

Received: 11 November 2024;  Published: 09 November 2025;  doi: 10.21926/obm.icm.2504048

Abstract

Morphological evidence of peripheral glial cell involvement is lacking. Therefore, we investigated the presence of Schwann cells in acupuncture meridians. Eight legs of four unembalmed cadavers were used. Along the stomach meridian and a control meridian, quadrangular samples were taken from skin to the deep subcutaneous fascia and embedded in paraffin. 5 µm sections were stained for H&E and processed for immunolabeling using antibodies against S100 and NFP, respectively. In the stomach meridian, a large assembly o [...]

688 2411

Open Access Original Research

Fabrication of CuO-Decorated Fe2O3 Nanoparticles as Efficient and Durable Electrocatalyst for Oxygen Evolution Reaction

Received: 09 August 2025;  Published: 07 November 2025;  doi: 10.21926/cr.2504009

Abstract

The electrochemical water oxidation application of CuO@Fe2O3 materials as potential catalysts is being reported for the first time. A series of CuO@Fe2O3 with different molar ratios of CuO (5, 7, 10, 12, and 15%) was fabricated through precipitation followed by the impregnation method. Structural and electrochemical studies were carried out by using different analytical platforms, including X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), Energy dispersive [...]

1210 3602

Open Access Original Research

Barriers Encountered When Implementing a Community Evidence-Based Fall Prevention Program

Received: 11 June 2025;  Published: 05 November 2025;  doi: 10.21926/obm.geriatr.2504330

Abstract

Falls and fall-related injuries are one of the leading causes of death among older adults aged 65+ in the United States. Americans’ life expectancy has increased and fall risk grows with age. While several evidence-based fall prevention programs are utilized to decrease fall risk among community-dwelling older adults, little research focuses on challenges or strategies related to sustained fall prevention program implementation. The purpose of this multi-method descriptive study was to assess fall risk outcome chan [...]

751 2621

Open Access Editorial

The Next Frontier in Photocatalytic Hydrogen Generation

Received: 24 October 2025;  Published: 03 November 2025;  doi: 10.21926/cr.2504008

1253 4046

Open Access Original Research

The Effect of Adding Mealworm, Probiotics, and Mealworm Plus Probiotics on IL-8 Gene Expression in Liver and Spleen Tissues of Broiler Chickens

Received: 30 July 2025;  Published: 30 October 2025;  doi: 10.21926/obm.genet.2504315

Abstract

Interleukin-8 (IL-8), a pro-inflammatory cytokine, plays a critical role in immune modulation in poultry and has potential applications in veterinary and human medicine. This study investigated the effects of dietary supplementation with mealworm (Tenebrio molitor), probiotics, or their combination on IL-8 gene expression in the livers and spleens of broiler chickens. A total of 160 one-day-old broiler chickens (Ross 308 strain) were assigned to four treatments (basal diet, basal diet + 0.2 g/kg probiotic, basal di [...]

883 3386

Open Access Original Research

Power of Ikigai on Japanese Older Adults’ Well-Being

Received: 15 May 2025;  Published: 30 October 2025;  doi: 10.21926/obm.geriatr.2504329

Abstract

In Japan, a super-aging society, the development of Ikigai is considered the key to extending healthy longevity in national policy. Thus, activities provided by local governments are designed to encourage Ikigai. At this point, Ikigai has developed its conceptual understanding, which includes its distinctiveness from life purposes and other closely related concepts. Empirical studies using developed measurements have shown that Ikigai has an impact on the mental and physical health of older adults across countries [...]

1771 12936

Open Access Review

Etiopathogenesis of Ebstein’s Anomaly Revisited

Received: 28 June 2025;  Published: 30 October 2025;  doi: 10.21926/obm.genet.2504314

Abstract

Ebstein's anomaly (EA) is a rare form of congenital heart disease (CHD), characterized by abnormal cardiac anatomy involving a defective tricuspid valve (TV), resulting in tricuspid regurgitation (TR) and cyanosis. EA is represented in different case scenarios with varying degrees of complexity across various age groups. It usually affects 0.2-0.7 out of 10,000 live births and accounts for 0.3%-0.6% of all CHD cases. While its occurrence is mainly sporadic, evidence from multiple studies suggests that EA can be ass [...]

5725 15678

Open Access Review

Healthy Ageing and its Communal Nemesis Social Frailty

Received: 11 June 2025;  Published: 29 October 2025;  doi: 10.21926/obm.icm.2504047

Abstract

Across the globe, countries are facing an ageing boom, with the proportion of the older adult population growing compared to younger age groups because of increased life expectancy and declining birth rates. Along with the ageing boom, there is increased interest in the wellbeing of older adults. Healthy ageing and social frailty are two constructs that have emerged in studying older adults and their quality of life. In this paper, we critically review salient literature defining and describing healthy ageing and s [...]

907 3478

Open Access Review

Clinical Trials Characterizing the Serum 25-Hydroxyvitamin D Response to Vitamin D Supplementation in Children: A Systematic Review and Meta-Analysis

Received: 13 September 2024;  Published: 29 October 2025;  doi: 10.21926/rpn.2504024

Abstract

Recommendations for vitamin D supplementation are essential for the prevention and therapy of vitamin D deficiency. However, reliable data remain lacking for children, as most intake recommendations are based on individual studies. This work aimed to obtain reliable data that allow health authorities to re-evaluate recommendations for oral vitamin D uptake in children. We conducted a systematic literature search in MEDLINE/PubMed on vitamin D supplementation in children. All randomized controlled trials (RCTs) publ [...]

1227 5958

Open Access Review

A Narrative Review on the Relationship Between Autistic Traits and Anxiety

Received: 31 May 2025;  Published: 27 October 2025;  doi: 10.21926/obm.neurobiol.2504307

Abstract

Although anxiety and Autism Spectrum Disorder (ASD) are common co-morbidities, the relationship between autistic traits and anxiety disorders/symptoms has been increasingly researched in recent years. This review aims to compile the studies conducted on this topic and enhance our understanding of it. All publications up to September 1, 2024, on PubMed that contained the terms ‘anxiety’, ‘autistic traits’, ‘autism feature’, ‘autism-like symptoms’, and ‘ASD-like symptoms’, in their titles or abstracts were reviewed. [...]

1263 5716

Open Access Interview

An Interview with Prof. Dr. Hanuman Singh Jatav

Received: 26 October 2025;  Published: 27 October 2025;  doi: 10.21926/aeer.2504030

683 3152

Open Access Original Research

Mechanisms of Self-Awareness, Influence, and Self-Identification

Received: 04 April 2025;  Published: 27 October 2025;  doi: 10.21926/obm.neurobiol.2504306

Abstract

World socio-political growth is shaped by globalization, integration, and multiculturalism, which also impact individual self-perception. Understanding personal development requires studying self-awareness, self-identification, and influence to identify internal requirements and external influences. The study examined self-awareness, self-identification, influence, and their relationships, as well as psychological interventions for self-assessment and self-realization. To attain the research goal, analysis, synthes [...]

1464 28086

Open Access Original Research

Investigating Associations between Maternal Mindfulness, Mental Health, Interoception and Mother-Infant Relationship during Pregnancy and Post-Partum in a Non-Clinical Community Sample

Received: 21 May 2025;  Published: 26 October 2025;  doi: 10.21926/obm.icm.2504046

Abstract

Pregnancy and the postpartum period are times of significant transition for women, with changes in maternal physical and mental health. The relationship between a mother and her infant has been recognised as laying the foundation for later child development. There is considerable evidence that this early relationship is influenced by a woman’s wellbeing during pregnancy and in the early post-partum period. Mindfulness has been found to have positive health outcomes, primarily in reducing maternal stress, anxiety, a [...]

976 3861

Open Access Original Research

Cultural Distance, Host Acculturation Orientation, and Psychological Adaptation among African International Students at Portuguese Universities

Received: 10 July 2025;  Published: 24 October 2025;  doi: 10.21926/obm.icm.2504045

Abstract

International students represent a significant sojourner group. Increasing international student numbers makes it ever more relevant to understand the determinants of their psychological adaptation. This research investigates the question of how perceived cultural distance (PCD) impacts acculturation variables (social contact with host nationals and host national identity) and outcomes such as saudade and life satisfaction among African international students. The sample comprised 422 college students (195 from Ang [...]

624 2929

Open Access Original Research

Deep Learning Approaches for Predicting Strain Energy in Heterogeneous Materials

Received: 15 July 2025;  Published: 24 October 2025;  doi: 10.21926/rpm.2504016

Abstract

This paper investigates data-driven strain energy prediction for heterogeneous elastic materials using the Mechanical MNIST benchmark dataset (60,000 28 × 28 stiffness maps by precomputed finite-element results). The results by classical regression models (linear regression, random forest, and gradient boosting) using hand-crafted features were compared with the results by the deep learning models (Convolutional neural network (CNN) and residual network (ResNet)) trained end-to-end on images. In held-out tests, CNN [...]

1053 3589

Open Access Original Research

BESS Sizing Optimization Combined with Optimal Scheduling Method Considering the Battery Degradation Using PSO

Received: 17 June 2025;  Published: 24 October 2025;  doi: 10.21926/jept.2504015

Abstract

Recently, renewable energy projects using storage systems have gained significant attention. This innovative technology requires a comprehensive investigation to overcome the technical and economic issues, which are related to optimal storage system capacity and operational requirements. In this study, an extensive battery energy storage system (BESS) sizing method was proposed considering four variables: charging and discharging scheduling, state of charge, BESS rate energy and power capacity, and degradation effe [...]

1660 6329

Open Access Original Research

Immunologic Response after COVID-19 Vaccination in Heart Transplant Recipients

Received: 30 June 2025;  Published: 21 October 2025;  doi: 10.21926/obm.transplant.2504259

Abstract

To date, all large-scale randomized controlled trials for COVID-19 vaccines have excluded solid organ transplant recipients; therefore, the effectiveness and safety of COVID-19 vaccines in preventing coronavirus infection using COVID-19 vaccines in patients with heart transplants have not been sufficiently studied. This paper presents the characteristics of humoral and cellular immunity in heart transplant recipients following vaccination against coronavirus infection. The study group consisted of 40 patients who u [...]

699 2905

Open Access Review

Mycotoxins Exposure: Neuroinflammation, Cognitive Decline and Behavioral Alteration

Received: 13 June 2025;  Published: 21 October 2025;  doi: 10.21926/obm.neurobiol.2504305

Abstract

Evidence from recent studies has suggested a significant association between mycotoxin exposure and neuroinflammation, potentially contributing to the onset of neurocognitive disorders during key developmental stages of the brain. Various research highlights how exposure to these toxins is correlated with a decline in cognitive performance, reduced motor skills, and behavioral issues. Mycotoxins are also implicated in interfering with neuronal signaling pathways and the functioning of neurotransmitters, which may l [...]

1348 7202

Open Access Review

Impact of Heavy Metals as Trace Elements on the Ecosystem and Health

Received: 10 June 2025;  Published: 21 October 2025;  doi: 10.21926/rpn.2504023

Abstract

Heavy metals are integral parts of our environment, originating initially from the universe and used in the industry, which may contribute to pollution. This book chapter aims to address the impact of heavy metals on the ecosystem and human health. Among the 32 heavy metals, eight belong to the group of essential ones: cobalt, copper, iron, manganese, molybdenum, nickel, selenium, and zinc. They were necessary in physiological amounts for the evolution of flora and fauna, including humans on earth, and are still ne [...]

1797 13174

Open Access Editorial

Life Sciences Worldwide – Global Perspectives and Networking for International Professionals1

Received: 15 October 2025;  Published: 16 October 2025;  doi: 10.21926/obm.icm.2504044

Abstract

The International Exchange of Professionals – Thematic Event in Life Science, held on October 15-17, 2025, in Nice, France, inaugurated a global congress series focused on frontier topics in biomedical sciences. This editorial summarizes the first day of the event, including the opening ceremony, keynote forum, and welcome banquet. With more than 150 participants from over 35 countries, the event created a platform for cross-disciplinary exchange and collaboration. Key themes included translational medicine, neurom [...]

889 3029

Open Access Research Article

Potential Synergistic Interaction Between Curcumin and Sorafenib Enhances Cytotoxicity in NCI-H5222 Lung Cancer Cells

Received: 25 August 2025;  Published: 15 October 2025;  doi: 10.21926/obm.genet.2504313

Abstract

Non-small cell lung cancer (NSCLC), accounting for approximately 85% of lung cancer cases, remains a leading cause of cancer-related mortality. Genetic alteration such as EGFR mutations, tobacco exposure, and resistance to apoptosis, slows its progression and limits therapeutic success. Although targeted therapies and immunotherapy have improved outcomes for select patients, resistance remains a major challenge, highlighting the need for more effective treatments. This study investigated the potential synergistic i [...]

892 3827

Open Access Review

Bridging Togo’s Energy Gap: Renewable Energy Potentials, Policy Challenges, and Strategic Pathways for Sustainable Development

Received: 22 December 2024;  Published: 13 October 2025;  doi: 10.21926/jept.2504014

Abstract

This work investigates the potential of renewable energy to significantly reduce Togo’s energy deficit, offering a critical analysis of the country’s current energy landscape. It evaluates the availability and viability of renewable energy sources—particularly solar and small-scale hydropower—and examines the mismatch between energy supply and growing demand. The study highlights Togo’s heavy reliance on biomass and energy imports from neighbouring countries such as Ghana, Côte d’Ivoire, and Nigeria, which exacerba [...]

1462 8335

Open Access Original Research

Network Topology Similarities Across Cancer Types: Identifying Central Protein Hubs for Drug Discovery

Received: 18 June 2025;  Published: 13 October 2025;  doi: 10.21926/obm.genet.2504312

Abstract

A molecular-level understanding of cancer is essential for the development of effective therapies. Constructing protein-protein interaction (PPI) networks offers a valuable approach to identifying dysregulated driver genes and potential therapeutic targets. In this study, we modeled cancer PPI networks as metric spaces and applied mathematical and computational algorithms to analyze their structural and functional properties. Our findings reveal that these networks share a conserved architecture across different ca [...]

862 3352

Open Access Editorial

Transcutaneous Auricular Vagus Nerve Stimulation (taVNS): Precise Integration Between Neuroscience and Integrative Medicine

Received: 10 September 2025;  Published: 10 October 2025;  doi: 10.21926/obm.icm.2504043

Abstract

Transcutaneous auricular vagal nerve stimulation (taVNS) is a non-invasive method that regulates the autonomic nervous system via electrical stimulation of the auricular branch of the vagus nerve. Recent literature demonstrates that taVNS can decrease systemic inflammation, attenuate emotional disorders, modulate autonomic functions, and facilitate neural plasticity. This review examines the neurophysiological mechanisms of taVNS, including stimulation paradigms (short- and intensive, prolonged), and clinical findi [...]

2748 12051

Open Access Original Research

When the Psychological Weight of the Burden Affects the Physical Weight of Caregivers of Older Patients in a French Memory Hospital (Lille, France)

Received: 23 May 2025;  Published: 10 October 2025;  doi: 10.21926/obm.geriatr.2504328

Abstract

Caring for patients with neurocognitive disorders (NCD) can be challenging for caregivers, with the risk of malnutrition. Observational, retrospective, monocentric study carried out with patient-caregiver dyads admitted to the Memory Day Hospital of the Gerontology Center of the University Hospital of Lille over 6 months in 2023. Our objectives were to identify the socio-characteristics of caregivers who had recently experienced a variation in their weight, their degree of fatigue (using the Fatigue Numerical Ratin [...]

803 2628

Open Access Original Research

The Influence of Gender and Academic Achievement on University Students' Perceptions of LMS-Based Self-Regulated Learning in Korea

Received: 28 April 2025;  Published: 09 October 2025;  doi: 10.21926/obm.neurobiol.2504304

Abstract

This study examines how university students perceive Learning Management System (LMS)-based instruction within the context of higher education, as they adapt to the rapid digital transformation. Specifically, it examines how students' perceptions differ based on gender and academic achievement, providing insights for more inclusive and adaptive instructional design. LMS platforms, when actively utilized, offer more than just content delivery—they can enhance classroom transparency, provide immediate feedback, promo [...]

935 4013

Open Access Original Research

Mindful Attention and Awareness Prospectively Predicts Stress in Daily Life: A Multilevel Modeling Approach

Received: 17 June 2025;  Published: 09 October 2025;  doi: 10.21926/obm.icm.2504042

Abstract

Chronic stress increases a person’s vulnerability for physical and mental health conditions that take root in the “common soil” of inflammation. Dispositional, or trait, mindfulness has been identified as a protective factor against perceived stress. However, the theory that trait mindfulness can prospectively predict lower perceived stress in natural settings has yet to be thoroughly tested. The current study used a daily diary prospective design to observe perceived stress in response to difficult events. Partici [...]

602 2636

Open Access Research Article

Technology Support to Enable People with Severe Intellectual Disability and Blindness to Carry Out Occupational Activities and Transition Between Them Independently

Received: 14 July 2025;  Published: 09 October 2025;  doi: 10.21926/obm.neurobiol.2504303

Abstract

People with severe intellectual disability and blindness tend to perform only simple occupational activities and are mostly unable to transition between those activities. This inability makes their level of occupation independent of staff support fairly limited. Technology-aided programs may be one of the few opportunities available to increase their independent occupation. This study assessed one such program designed to (a) monitor the participants’ responses and guide them to transition to a new activity once th [...]

744 2916

Open Access Interview

An Interview with Dr. Blanca Hernandez-Ledesma

Received: 28 August 2025;  Published: 09 October 2025;  doi: 10.21926/rpn.2504022

592 2032

Open Access Original Research

Evaluation of the Transitional Pain Service Specialized Iyengar-Informed Yoga Program for Chronic Post-Surgical Pain: A Pilot Randomized Controlled Trial

Received: 29 April 2025;  Published: 30 September 2025;  doi: 10.21926/obm.icm.2503041

Abstract

The objective of this randomized controlled trial (RCT) was to evaluate the feasibility and efficacy of a specialized Iyengar-informed yoga intervention for individuals who experience chronic post-surgical pain (CPSP). This prospective, multi-wave pilot RCT was pre-registered at clinicaltrials.gov (NCT03460028) and designed in accordance with the 2010 CONSORT statement. Participants (N = 21) with CPSP were out-patients or community members affiliated with a Toronto hospital. Participants were randomized to an 8-wee [...]

928 3457

Open Access Review

The Impact of Vitamin D on Type 2 Diabetes Mellitus: Exploring Its Role in Glucose Metabolism and Insulin Sensitivity

Received: 15 May 2025;  Published: 29 September 2025;  doi: 10.21926/rpn.2503021

Abstract

Vitamin D, a fat-soluble secosteroid, plays a pivotal role beyond its functions in calcium and bone homeostasis. Emerging evidence suggests its involvement in glucose metabolism and insulin sensitivity, thus influencing the pathophysiology of Type 2 Diabetes Mellitus (T2DM). For the current review, a search was conducted across four major databases: PubMed, Embase, Google Scholar, and Web of Science. The aim was to identify relevant studies and clinical trials, published in English, reporting the mechanistic insigh [...]

1545 8489

Open Access Editorial

World Federation of Acupuncture-Moxibustion Societies (WFAS)/Acupuncture Science Association Sweden (ASAS) 2025 International Congress – Personal Report1

Received: 24 September 2025;  Published: 25 September 2025;  doi: 10.21926/obm.icm.2503040

Abstract

This personal report summarizes the key experiences and insights gained from attending the 2025 International Symposium organized by the World Federation of Acupuncture-Moxibustion Societies (WFAS) and the Acupuncture Science Association of Sweden (ASAS), held in Stockholm. The event brought together international experts to explore recent advances in acupuncture research, clinical applications, education, and global integration. Despite notable challenges—including issues with AI-assisted real-time translation and [...]

1319 5808

Open Access Original Research

Effect of EVA on the Unnotched Impact Toughness of PP/HDPE/EVA Blends

Received: 29 May 2025;  Published: 24 September 2025;  doi: 10.21926/rpm.2503015

Abstract

Beverage bottle caps are usually made from two primary materials: PP and HDPE. In this study, the evaluation criteria were the unnotched impact toughness and the microstructure of PP/HDPE/EVA samples produced by injection molding. The samples were tested according to ASTM D256. PP/HDPE/EVA blends were prepared with various ratios: 47.5/47.5/5, 45/45/10, 42.5/42.5/15, 40/40/20, and 37.5/37.5/25. The results showed that adding EVA to the PP/HDPE blend significantly increased the unnotched impact toughness: from 84.03 [...]

1222 5528

Open Access Original Research

Interactive and Deep Learning-Powered EEG-BCI for Wrist Rehabilitation: A Game-based Prototype Study

Received: 14 August 2025;  Published: 24 September 2025;  doi: 10.21926/obm.neurobiol.2503302

Abstract

Motor deficits induced by neurological disorders impose a severe impact on activities of daily life. Conventional rehabilitation practices necessitate ongoing clinical supervision, which is costly and inaccessible. EEG-based brain-computer interface (BCI) systems offer a viable solution by facilitating neurorehabilitation through the direct interpretation of brain signals. Nonetheless, current systems are confronted with issues of real-time control, portability, and classification precision. The paper describes a n [...]

1599 9525

Open Access Review

A Systematic Literature Review for the Development of a Consolidated Method for DLCA

Received: 28 May 2025;  Published: 23 September 2025;  doi: 10.21926/rpse.2503014

Abstract

Dynamic Life Cycle Assessment (DLCA) is an emerging approach in the construction industry it is. Yet, current research is often limited, overlooks operational patterns, and relies on generic case studies, highlighting the need for an extended method to apply these analyses in the built environment. This study conducts a Systematic Literature Review to evaluate the current state of DLCA research and identify key steps toward developing a unified and globally applicable methodology. Using the PRISMA protocol, 69 peer [...]

1346 5696

Open Access Research Article

A Randomized Control Trial of the Effects of a Hatha Yoga Program on Psychological Well-Being

Received: 11 March 2025;  Published: 23 September 2025;  doi: 10.21926/obm.icm.2503039

Abstract

Hatha yoga is a common style of yoga used for physical, emotional, mental, and spiritual benefits, enhancing quality of life and well-being. The current study used a randomized control trial (RCT) to investigate whether completing an eight-week posture-based Hatha yoga program would lead to greater psychological benefits than taking part in an eight-week lecture series about the history and philosophy of yoga. Fifty-five participants (42 female, age range 18-32) completed five self-report measures both before and a [...]

1040 7001

Open Access Editorial

Iron-Based Nanoparticles for Water and Soil Treatment

Received: 15 September 2025;  Published: 22 September 2025;  doi: 10.21926/aeer.2503029

1399 4629

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