Highlights of Complementary and Alternative Medicine in Nervous System Conditions: An Interview with Dr. James David Adams, Jr.Abstract
Highlights of Complementary and Alternative Medicine in Nervous System Conditions: An Interview with Dr. James David Adams, Jr. 1175 7003 |
Meditation, Sleep, and PerformanceAbstract
Meditation describes a large variety of traditions that are extremely variable, but all include the conscious focus or awareness of attention. By maintaining their attention, meditators experience both acute and long-term changes in physiology, anatomy, and cognitive performance. The literature shows that the type of performance benefits may depend on the specific type of mental training. During meditation practice there is a documented increase in neuronal coordination and slowing of neuronal firing across many re [...] 2362 33236 |
The Link(s) between Compassion and Healingby
Kristi Kanel
Abstract
While it may seem intuitive to suggest that compassion aids in the healing process, there is actual evidence to support that compassion changes physiology, which in turns affects emotional and physical healing. The focus of this opinion paper is on the use of compassion between health care providers and patients based on the use of compassion in the mental health field. Not only do patients benefit from compassion, but health care providers may also benefit. Creating compassionate relationships with patients may [...] 1600 7187 |
Lifestyles and Complementary Medicine: A Survey in the Region of Tuscanyby
Mariella Di Stefano
,
Sonia Baccetti
,
Elio Rossi
,
Maria Valeria Monechi
,
Barbara Cucca
,
Sergio Segantini
,
Elisabetta Barbara Cortesi
,
Fabio Voller
,
Eleonora Fanti
,
Alice Berti
and
Stefano Bravi
Abstract
Background: According to the international literature, users of Complementary Medicine (CM), Complementary and Alternative Medicine (CAM) and Complementary and Integrative Medicine (CIM) are physically more active, less overweight and have healthier lifestyles than the average Tuscan population. Aim: To evaluate the socio-demographic characteristics and lifestyles of patients of CM public clinics in the region of Tuscany and to define their profiles in terms of physical exercise, smoking habits, diet, intake of alc [...] 1957 10912 |
Observational Study on Auriculotherapy in the Treatment of Chronic Musculoskeletal Pain: Preliminary Databy
Elisabetta Barbara Cortesi
,
Sonia Baccetti
,
Maria Valeria Monechi
,
Mariella Di Stefano
,
Barbara Cucca
,
Tommaso Conti
,
Antonella Traversi
,
Filippa Terranova
,
Roberto Montelatici
,
Sylvie Yvonne Barberousse
,
Federica Sabatini
,
Catia Vuono
,
Christian Bini
and
Marco Picchi
Abstract
Introduction: Pain in musculoskeletal disorders is a common problem that involves high social and individual costs. Systematic reviews and randomized controlled trials show that a number of treatments usually applied in this field are not effective. On the other hand, there is clinical evidence of the effectiveness of physical exercise, acupuncture, and auriculotherapy. Side effects of current medication limit their use. Aim: To evaluate the effectiveness of auriculotherapy on the pain of patients suffering from ch [...] 2253 16924 |
Integrative Cancer Therapy with Special Focus on Add-On Homeopathy: The Experience at Lienz HospitalAbstract
The first part of this position paper focuses on the debate about the scientific status of homeopathy and presents some answers. The scientific debate however, does not represent the available scientific evidence, which actually supports our limited data. Thus, it seems important and we aim to present how homeopathy can be part of an integrated concept in cancer care and how this is approved by randomized controlled trials. We present some arguments which were helpful to us in the discussion with oncologists that d [...] 1945 8808 |
The Role of Self-Compassion in Recovery from Substance Use Disordersby
Gila Chen
Abstract
Background: A large body of empirical evidence has supported the notion that individuals with substance use disorders (SUDs) have difficulty regulating their negative emotions and employing emotion-regulation strategies. The aim of this article is to (a) explore the role of self-compassion in providing an emotion-regulation strategy for initiating a process of recovery from SUDs; (b) examine the role of self-compassion in building recovery capital (RC) to promote long-term recovery; and (c) examine the practice of [...] 4672 27716 |
Compassion in Medicine – A Psychiatric Physician’s ViewAbstract
There are several definitions of sympathy, empathy, and compassion on the internet. I have chosen the above definitions to emphasize their salient differences, for the following reason: In medical school, in the early 1960s, we were taught not to sympathize with patients, but to empathize: By empathizing, one can retain some professional objectivity toward the patient, in order to be of some help. To sympathize, on the other hand, was to immerse oneself in the patient’s suffering and lose one’s professional per [...] 1603 8127 |
Integrated Medicine Strongly Improves Post-Stroke Rehabilitative Performance in a Public Health Facility in Italyby
Simonetta Bernardini
,
Francesca Bechini
,
Giulia Braccesi
,
Franco Cracolici
,
Rosaria Ferreri
,
Roberto Pulcri
and
Andrea Serafini
Abstract
Since 2011, the Tuscany Regional Authority has been funding the use of Integrated Medicine (IM) in a clinical setting in Pitigliano Hospital, with the aim of testing the true efficacy of complementary and alternative medicine (CAM) in a hospital setting. The clinical setting also comprises the Manciano rehabilitation facility whose services include post-stroke rehabilitation. This study aims to establish if IM helps to improve the rehabilitation performance of stroke patients. The study compared 212 patients divide [...] 1887 16951 |
Unexpected Long Survival of a Patient with Polycythemia Veraby
Michael Frass
and
Katharina Gaertner
Abstract
This case reports of a 71-year-old patient with polycythemia vera (PCV). Homeopathic treatment began 15 years after his diagnosis at the age of 51. The frequency of phlebotomies was lowered significantly after the start of the homeopathic treatment; the patient survived another 16 years without chemotherapy, which he had rejected despite appropriate education. For someone with PCV who denied chemotherapy, this patient had a long survival time of more than 30 years, essentially enjoying good health and high quality [...] 2140 32721 |
The Process of Integration of Complementary Medicines in Public Healthcare Service of Tuscany (Italy)Abstract
Complementary Medicine (CM) is being increasingly used by European citizens in order to increase their overall state of health and well-being, as well as to treat various illnesses and diseases. The interest for these therapies has progressively risen also in Italy and in Tuscany as well. In response to the increasing demand in the past few years by the Tuscan citizens, the region of Tuscany has started their integration in the healthcare service. Since 1996, the Tuscan Regional Healthcare Plans (RHPs) have been co [...] 1977 12222 |
Comparison of Respiratory Sinus Arrhythmia between Zen-meditation and Control GroupsAbstract
Background: This research aims to develop new methods to investigate the cardiorespiratory interaction of Zen-meditation practitioners (Zen-meditation group) and healthy ordinary young people (control group) by quantitatively evaluating respiratory sinus arrhythmia (RSA) behavior. Methods: Twenty-five voluntary controls and seven Zen-meditation practitioners were recruited. The experimental protocol involved five sessions of different mental-stress levels (control group) and five sessions of Zen-meditation practice [...] 1994 16843 |
Acupuncture for Chemo-Related Nausea and Vomitingby
Carmelo Guido
,
Valentina Selmi
,
Cosimo Chelazzi
,
Giulia Borsotti
,
Rita Giachetti
,
Vittorio Limatola
,
Martina Sicurani
and
Angelo Raffaele De Gaudio
Abstract
Background: In recent years, complementary and alternative medicine (CAM) techniques have become very widespread; among these, acupuncture can play an important role in the treatment of adverse effects related to chemotherapy. This role has been recognized by the National Institutes of Health after many clinical studies, thus allowing the official introduction of acupuncture in supportive therapy for oncological diseases, particularly to prevent nausea and vomiting. The aim of this paper is to describe the activity [...] 2221 11816 |
Increase in Electrodermal Activity on Acupuncture Points of Lymphatic, Lung, Nervous, Endocrine and Heart Meridians after Running Exercise, a Single Case StudyAbstract
Background: Electrodermal measurement of acupuncture points has been correlated to physiologic and pathologic conditions with clinical and laboratory studies. Emerging evidence indicates that in addition to therapeutic effect, acupuncture points may also have diagnostic properties. However, physiologic basis of this phenomenon is still unknown. Objective: To determine how electrodermal activity of acupuncture points on hands and feet responds to exercise-induced sympathetic stress and how electrodermal measurement [...] 2155 16383 |
The Effects of Aquatic Exercise on Cognitive Function: Systematic ReviewAbstract
The objective of this brief systematic review was to examine the effects of aquatic exercise on cognitive function. Studies were identified using electronic databases, including PubMed, PsychInfo, Sports Discus and Google Scholar. In total, 13 articles met the inclusionary criteria. Among the 13 studies, all 13 demonstrated beneficial cognitive effects from exercise. This included chronic aquatic exercise-induced improvements in global cognition, executive function, attention, learning and memory, cognitively-relat [...] 3107 15354 |
Proposal for a Compassionate Emotional Accompaniment Technique (CEAT) Based on Mindfulness to Manage Disturbing EmotionsAbstract
One of the objectives of psychological intervention is to help patients manage their emotions effectively by providing them with the necessary skills to accompany their own emotional states. To this regard, there seems to be a current lack of therapeutic resources aimed at helping patients assimilate and regulate emotions. This article proposes the application of a new technique which incorporates mindfulness, building on the premises of the model of psychological flexibility which defines "mindfulness" as a practi [...] 1995 11610 |
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Psychophysiological Coherence in Community Dynamics – A Comparative Analysis between Meditation and Other ActivitiesAbstract
Background: Psychophysiological coherence has been widely studied as a bodily state associated with general well-being and cognitive clarity. Heart Rate Variability (HRV) has been shown to be a good biomarker to assess psychophysiological coherence. This paper presents the first general set of results concerning a study that is part of a team effort between a body of researchers in 5 countries led by the HeartMath Institute under the name, International Heart Rate Variability Synchronization (IHRVS) Study. This stu [...] 2057 13428 |
The Treatment of the Nervous System with Complementary and Alternative MedicineAbstract
The nervous system is everywhere in the body, especially in the skin. Ancient Chinese acupuncture charts show us that the nerves are all connected and can work together to promote health. This connection occurs through the brain and brain stem. It is clear that acupuncture is analgesic by inhibition of transient receptor potential cation channels in the skin [1]. The role of chemokines in pain is becoming understood. Chemokines promote pain in the skin and activate ascending neural pathways that regulate chemo [...] 1788 8719 |
New Paradigm in International Ear AcupunctureAbstract
Background: In the international auriculotherapy practice there are relatively big differences in the exact localization of the same ear acupuncture point. On one hand, there are specialists who devote their efforts to find the active points. In that case it becomes intriguing that there may be another point (at 1-2 mm distance) near the point to be treated, indicating a relatively strong, even stronger activity than the one they were initially aiming to find. That point may be active because of another health prob [...] 3062 45140 |
Chronic Pain after Reported Whiplash Injury – A Patient Case Reportby
Gunnel Berry
Abstract
Chronic pain is notoriously multifactorial, multifaceted and difficult to manage. Twenty per cent of reported whiplash-injured persons go on to develop a Whiplash Associated Disorder (WAD) where persistent pain becomes chronic with no prospect of change [1]. Paucity of effective therapies to address the effect of WAD enforces new approaches. This case report, with a patient’s perspective, illustrates a novel therapy, Adapted Reflextherapy (AdRx), which is akin to reflexology and has been used, developed and revised [...] 1943 16400 |
A Brief Primer on Learning and Memory-Based Strategies to Enhance Memory FunctionAbstract
Background: Learning and memory, unquestionably, are critical for many aspects of life, including acquisition and retention of educational material. The purpose of this brief narrative review is to provide a primer on empirical-based, learning and memory techniques. Methods: A narrative review approach is employed. Results: This review is structured by first discussing contextual factors that influence learning and memory, followed by addressing several specific techniques to help facilitate learning and memory ret [...] 2046 10366 |
An Initial Investigation of Neural Changes in Overweight Adults with Food Cravings after Emotional Freedom TechniquesAbstract
Background: This pilot randomised clinical trial investigated the effect of Clinical Emotional Freedom Techniques (EFT) on brain activation in response to food craving stimuli using functional magnetic resonance imaging. EFT is a brief stress reduction technique which involves stating a cognitive statement with stimulation of acupressure points with a tapping technique. Method: Fifteen overweight/obese adults were allocated to a four-week group EFT treatment or control condition and completed a measure of food crav [...] 2818 877229 |
An Evaluation of a New Programme Training Mindfulness Teachers to Deliver Non-Eight Week Adapted Mindfulness-Based Interventionsby
Robert Marx
and
Lisa Burroughes
Abstract
Background: Training is generally not available for those wishing to deliver non 8 week Mindfulness Based Interventions (MBIs) adapted for specific contexts and populations. A new model for training in MBIs is developed with the following principle components: teaching on theory, participation in a practice, followed by teaching the practice and receiving feedback, and consultation and discussion of live mindfulness-based work. Methods: A quantitative and qualitative evaluation is presented of the experience of the [...] 1899 9680 |
Integrated Oncology in an Integrated Medicine Hospital in Pitigliano (Grosseto, Italy)Abstract
Background: Complementary medicines (CM), including homeopathy, acupuncture, and traditional Chinese medicine, have been introduced for cancer patients undergoing chemotherapy and radiotherapy treatment in the Pitigliano Hospital Centre of Integrated Medicine in order to minimize the side effects of these treatments, which improves quality of life and adherence to conventional therapies. Methods: Cancer patients (240) were enrolled in an integrated care model offering a comprehensive protocol including homeopathy a [...] 1757 9198 |
Is Self-Compassion Important for Health Care Practitioners?Abstract
The cornerstone of health care practice is the provision of competent, compassionate care. Compassion is generally considered an important component in the provision of health care; however, self-compassion may be of equal importance for health care practitioners (HCP) to observe and develop. Self-compassion promotes well-being and overall mental health and may reduce fatigue and “burn-out” for HCPs [1]. Estimates of burn out in physicians and nurses range from 35-50% and is associated with emotional exhaustion, hi [...] 2707 16875 |
Acupuncture in Palliative CareAbstract
Background: Acupuncture is an innovative and scientifically supported treatment for oncologic patients, as well as an effective palliative care option. At the Palliative Care Department of "Misericordia" Grosseto Hospital in Tuscany, real integration of acupuncture in palliative medicine has been possible. The objective of this work is to retrospectively evaluate patient treatment outcomes obtained using an integrated medical care approach administered within a palliative care unit. Methods: Medical records of onco [...] 5725 14048 |
Ashitaba (Angelica keiskei) Exerts Possible Beneficial Effects on Metabolic SyndromeAbstract
Metabolic syndrome is a serious health condition comprising a combination of glucose metabolism disorder, high blood pressure and obesity. The main underlying risk factors for metabolic syndrome are abdominal obesity and insulin resistance. Various studies have shown that herbal medicines can effectively reduce the risk of developing metabolic syndrome. Angelica keiskei Koidzumi (ashitaba), a large perennial herb native to the Southeast Pacific coast of Japan, has recently become a popular herbal medicine, dietary [...] 2674 28127 |
Mindful Self-Compassion and Adult Learner Retention in Post-Compulsory EducationAbstract
Background: Adult learners often engage in formal education because they want to create changes in their lives and are determined to succeed in their chosen field. However, they also come with emotional "baggage" of early educational experiences, frequently have to deal with a multitude of competing demands, have financial strain, may face a lack of support, illness and/or injury. In addition, they are often dealing with the challenges of unfamiliar academic work, competing deadlines and initially lack basic academ [...] 2161 14558 |
Cultivating Well-Being through the Three Pillars of Mind Training: Understanding How Training the Mind Improves Physiological and Psychological Well-BeingAbstract
Research on the physiological and emotional health benefits of meditative practices has grown exponentially over the last two decades, influencing both scientific literature and popular media. Research has highlighted three distinct components or pillars at the core of meditative practices and mind training. They are, focused attention, open awareness, and kind intention. Neuroimaging studies and recent research highlight that the repeated practice of directing attention and awareness can enhance neural connections [...] 3422 32346 |
Health Benefits of (Mindful) Self-Compassion Meditation and the Potential Complementarity to Mindfulness-Based Interventions: A Review of Randomized-Controlled TrialsAbstract
Background: In this study, we performed a systematic review of randomized-controlled trials (RCTs) examining the health benefits of (mindful) self-compassion-based interventions (SCBIs) and studies which explicitly combine SCBIs and mindfulness-based interventions (MBIs). Based on the compelling evidence supporting the effectiveness of MBIs, we evaluated the potential use of MBIs and SCBIs to complement one another, and whether SCBIs may serve as supplementary, or preliminary interventions for individuals not fully [...] 2907 22528 |
State of the Research: Physical and Mental Health Benefits of Mindfulness-Based Interventions for Children and Adolescentsby
Randye J. Semple
and
Christine Burke
Abstract
Background: Research support for a variety of health benefits of mindfulness-based interventions for adults is robust. These include management of stress, anxiety, and depression; as a supportive treatment for eating disorders, PTSD, and psychosis; improved sleep; chronic pain management; support for tobacco, alcohol, and substance abstinence; and as adjunctive treatments for serious or chronic medical illnesses such as HIV, cancer, and heart conditions. As is typical with newer interventions, mindfulness intervent [...] 4296 45478 |
Mindfulness Based Therapies for Autoimmune Diseases and Related Symptomsby
J. Kim Penberthy
,
Dinesh Chhabra
,
Nina Avitabile
,
J. Morgan Penberthy
,
Ngan Le
,
Yiqin Roger Xu
,
Seara Mainor
,
Natalie Schiavone
,
Paul Katzenstein
,
Janet E Lewis
and
Leslie Hubbard
Abstract
Over the past few decades, there have been minimal advances in effective new behavioral or psychotherapeutic interventions for people living with autoimmune diseases such as systematic lupus erythematosus. This is problematic due to the severe, debilitating and potentially life-threatening nature of these diseases. Mindfulness based interventions, such as Mindfulness Based Stress Reduction, have demonstrated effectiveness in a wide range of patient populations and we hypothesize such treatment would also benefit pa [...] 2496 22469 |
Healthcare Provider’s Guide to Kratom: Succinct Introduction to the Basics and the QuestionsAbstract
Background: The leaves of Mitragyna speciosa (kratom), a tropical tree that is indigenous to Southeast Asia, have been used traditionally to increase stamina, as a digestive aid, and as an analgesic. Kratom use is now increasingly popular in the rest of the world because of easy availability through the Internet and real, or perceived, views of efficacy and safety. Methods: PubMed and MedLine searches were conducted of published articles available in English. Results: Mitragynine and 7-hydroxymitragynine are the pr [...] 1898 12384 |
Binary Model of the Dynamics of Active versus Passive Mindfulness in Managing Depressionby
Andrew Hede
Abstract
Background: Meditation has developed over many centuries within a diverse range of religious traditions including Middle-Eastern, Indian, and East-Asian. Of these, mindfulness meditation from the Buddhist (Indian) tradition, has been the most extensively adopted in the Western secular world primarily with applications in health and well-being as pioneered by Jon Kabat-Zinn.
Review: While originally developed to treat chronic pain and stress in the U.S., mindfulness training was later coupled with cognitive-behavior [...] 1973 13443 |
Evaluating a 3-Week Model for Reducing Symptoms of Stress in Traumatised Youth Using the Trauma Tapping Technique (TTT) for Self-help: A Pilot TrialAbstract
Background: This pilot trial investigated whether a 3-week self-help model for stress reduction using the Trauma Tapping Technique (TTT) would impact traumatized youth in the Democratic Republic of the Congo on post-traumatic stress symptoms and general happiness. It also focussed on the acceptability of the program to recipients and implementation in a community with complex trauma and conflict.
Methods: The study involved 77 youth who received a TTT 3-week model of intervention (self-applied). Post traumatic stre [...] 2239 22577 |
Chronic Pain Two CuresAbstract
Background: This study presents several case reports of chronic pain patients treated with two different plant medicines from the Chumash Indian tradition.
Methods: Patients suffering from self-reported fibromyalgia, chronic back pain, chronic bursitis, chronic tendinitis and other conditions were treated. California sagebrush (Artemisia californica) was grown by the author and made into a liniment. The liniment was applied to painful sites on the skin. Black sage (Salvia mellifera) was made into a sun tea. Chronic [...] 2077 9665 |
Experimental Effects of Exercise on ForgettingAbstract
Background: The present study evaluates the effects of selective directed forgetting (SDF) and directed forgetting (DF) on subsequent memory retrieval and investigate whether acute exercise can facilitate the effects of SDF.
Methods: A four-arm (n=20 per group; N=80; Mage=20 yrs), parallel-group, randomized controlled experiment was employed. The four groups included: 1) exercise plus SDF (Ex+SDF), 2) SDF only (SDF), 3) DF only (DF) and 4) R (remember) only (R). Participants viewed two separate word lists (list 1 a [...] 2003 10616 |
The Lived Experience of Individuals with Chronic Traumatic Brain Injury: An Adapted Group Yoga InterventionAbstract
Background: An adapted yoga intervention was delivered to seven individuals with chronic traumatic brain injury. The purpose of this study was to explore and describe the participants' experience of engaging in the 8-week intervention.
Methods: Using a phenomenological design, data were collected, analyzed, and coded to generate themes regarding experiences that occurred, how experiences occurred, and why experiences occurred.
Results: Participants described experiencing the yoga intervention as a process: from ini [...] 1448 9364 |
Meditation and Immune Function: The Impact of Stress Management on the Immune Systemby
Nicole Thibodeaux
and
Matt J. Rossano
Abstract
As alternative forms of medicine have become increasingly popular, research on the health benefits of meditation has grown. Specifically, Mindfulness Meditation, Transcendental Meditation, and Qigong have been shown to be effective in treating psychological disorders, enhancing immune function, and in delaying disease progression in patients diagnosed with HIV, the varicella-zoster virus, and dermatomyositis. This paper briefly reviews the historical background of the many forms of meditation and examines in detail [...] 3379 55578 |
Complementary and alternative treatment of MS – A study of three casesby
Katarina Mark
and
Maria Arman
Abstract
Background: People suffering from multiple sclerosis (MS) commonly use complementary and alternative medicine due to the partial efficacy of conventional treatments, the chronic aspect of MS, the impact of pain and the side-effects of medication. An exploratory descriptive study of three cases was performed to document and analyse the experience patients treated for MS with applied kinesiology. Methods: Qualitative interviews were conducted with three patients who had been diagnosed with MS at the Neurology Departm [...] 2026 19954 |
What is the Current Evidence to Support the Use of Herbs and Supplements to Treat Mood and Anxiety Disorders?by
Megan Berberich
and
Bettina Bernstein
Abstract
Background: Treatment of mood and anxiety disorders with supplements, herbs and nutraceuticals (dietary supplements) is at this point viewed as an integrative or alternative treatment, however these substances have been around for quite some time and are regarded as basic to the understanding of human biochemistry, physiology, health and illness in medicine. Methods: This review article was done using a literature search utilizing the National Library of Medicine online data base and the PCOM electronic library dat [...] 2577 20662 |
Meditation: Awakening the Intuitive and Creative SelfAbstract
What is meditation? A tool that empowers you to create your life through working it from inside out, beginning with a thought.
There is a story. A father had two sons: one felt a victim of life. He viewed his life through the prism of “My childhood was difficult. My father was an alcoholic. The reason my life is failing is because of that. I was not loved enough.” This is his inner mantra – a cycle of a repetitive thought patterns that he continuously told himself. His life followed that very mantra. He didn’t try [...] 1712 8826 |
Impacts of Mindfulness-Based Cognitive Therapy (MBCT) on the Psychological and Functional Wellbeing of Patients with Bipolar DisordersAbstract
Background: This study investigated variations in psychic and somatic anxiety during and after completion of MBCT compared to baseline in patients diagnosed with BD. Secondary variables considered were sleep quality and quality of life, as well as depressive and manic symptoms. Methods: HAMD-29, HAMD-7 and YMRS were administered at baseline (n=34), and every two weeks until the end of the eight-week program. PSQI (n=22) and Q-LES-Q-SF (n=29) were also administered at pre, mid- and post- MBCT assessments. Results: T [...] 1781 14778 |
Integrating Mindfulness and Physical Exercises for Medical Students: A Systematic Reviewby
Marcus A. Henning
,
Tae Joo Park
,
Fiona Moir
,
Chris Krägeloh
,
Christopher Mysko
,
Jennifer Hobson
and
Craig S. Webster
Abstract
Background: The purpose of this systematic review was to appraise the empirical evidence pertaining to medical students and the integration of mindfulness and physical exercise regimens. Methods: A systematic review was undertaken. Five databases were used to survey the salient literature. Results: The initial search identified 353 potentially relevant articles of which 17 articles were considered for the final review. The findings indicated that the research was mainly conducted in the USA with some research origi [...] 2159 12251 |
A Mixed Methods Approach to Understanding Conceptions of Mindfulness MeditationAbstract
Background: Mindfulness meditation (MM) is an increasing area of interest for health professionals and the general public alike. Beneficial outcomes are associated with this practice; however, definitions of mindfulness and meditation are varied, and anecdotal accounts suggest that people hold conceptions about the constructs. Furthermore, mindfulness has been incorporated into therapeutic modalities without much consideration for context, including the client’s previous experiences with and understanding of MM. To [...] 1994 12026 |
Meditation as an Intervention for Health: A Framework for Understanding Meditation Researchby
Marcel Allbritton
and
Carrie Heeter
Abstract
We propose a framework for understanding meditation that can support greater scientific rigor in reporting meditation research, and selecting meditation health interventions. There is no consistent and thorough framework for describing meditation research interventions. This impedes rigor of meditation research design and interpretation of findings. This also limits meaningful comparisons across research studies. The audience for this article includes researchers, meditation experts, healthcare professionals, and t [...] 2897 15676 |
Feasibility of a Meditation Video Game to Reduce Anxiety in College Studentsby
Paul A. Barclay
and
Clint A. Bowers
Abstract
(1) Background: Meditation is a common intervention for college students suffering from issues with anxiety. Due to this popularity, several meditation-based video games have been released which can be used to supplement or motivate meditation practice. However, these tools are not often given scrutiny in a laboratory setting before being released to the public. Our lab conducted a brief feasibility pilot study to investigate Meditation Deathmatch, an open-source meditation video game aimed at stimulating meditatio [...] 2259 32849 |
Specific Somatic Symptoms Alleviated by Mindfulness Meditation TrainingAbstract
Background: Mindfulness-Based Stress Reduction (MBSR) is an evidence-based intervention developed to teach mindfulness meditation to a wide range of patients. Although the efficacy of MBSR has been established for a variety of medical and psychiatric conditions, measured outcomes rarely include physical symptoms related to anxiety, depression, and/or stress. The current study presents a secondary analysis of data obtained from patients seeking MBSR for symptoms of anxiety, depression, and/or other stress-related co [...] 2003 14279 |
Fructose Increases Uric Acid Contributing to Metabolic Syndrome - Herbal, Nutritional and Dietary Strategies to Reduce Uric AcidAbstract
The metabolism of fructose by the liver produces uric acid and elevated serum uric acid levels are an independent risk factor for hypertension, metabolic syndrome, and cardiovascular disease. Fructose occurs in fruits and fruit juices, honey as well as in the sweeteners sucrose (common white sugar) and High Fructose Corn Syrup (HFCS). Dietary fructose may be considered a naturally occurring toxin because it is largely metabolised by the liver with little fructose reaching the systemic blood circulation. Uric acid i [...] 3211 196931 |
Potentially Beneficial Effects of St. John’s Wort (Hypericum perforatum) in Patients with Metabolic SyndromeAbstract
St. John’s wort (SJW), or Hypericum perforatum, is a perennial herb that is used to treat depression in several countries. Based on the available evidence, it can be hypothesized that SJW would also have beneficial prophylactic and therapeutic effects in patients with metabolic syndrome. In this review, we summarize and discuss the best designed studies that have investigated the effects of SJW extract on adipocyte differentiation, the inflammatory process, and glucose metabolism, all of which are relevant to [...] 2139 16478 |
Thai Ethnomedicinal Plants Used for Diabetes Treatmentby
Methee Phumthum
and
Henrik Balslev
Abstract
Background: Diabetes is a metabolic disorder and a serious global health problem. Over 400 million people suffer from diabetes and it is estimated that the number will dramatically increase in the future. The cost of diabetes treatment for individual patients is very high. However, traditional knowledge could be used to support conventional diabetes treatments. Here, we identify medicinal plants that have been used as treatments for diabetes based on Thai ethnobotanical knowledge. Methods: We present a literature r [...] 3010 21492 |
Pain in Oncology, Reality and Paradox of Homeopathic CareAbstract
Background: After fatigue, pain is one of the major complaints from cancer patients. Regular use of Class 1 analgesics may cause side effects and is not always sufficient to relieve pain. Homeopathy is the complementary and integrative medicine most frequently used in France in supportive care in oncology (SCO). What is its place in the treatment of pain? Method: Extraction and analysis of results concerning pain from three surveys, two of which were carried out in France, on the main indications of homeopathy in S [...] 2128 25942 |
A Review of the Efficacy of Yoga and Meditation-Based Interventions for Rheumatoid Arthritisby
Alexandra Koulouris
,
Kathleen Dorado
,
Christina McDonnell
,
Robert R. Edwards
and
Asimina Lazaridou
Abstract
Background: This paper presents a review of the evidence regarding the efficacy and impact of Yoga and mindfulness with meditation among patients with rheumatoid arthritis (RA). Patients who suffer from RA express a variety of symptoms that negatively impact their physical functioning and performance in social roles. Yoga and meditation-based therapies have been previously used to manage chronic pain conditions and other persisting disorders in affected populations. The suitability and effectiveness of these practi [...] 2120 12610 |
Homeopathy and Complementary Integrative Medicine, Dietary and Lifestyle Advices to Reduce Adverse-Effects of Anti-Cancer Therapy: A Cohort Study with Breast Cancer Patientsby
Elio Rossi
,
Cristina Noberasco
,
Marco Picchi
,
Mariella Di Stefano
,
Linda Nurra
,
Antonella Rossi
and
Leonardo Ventura
Abstract
Background: To manage the adverse effects of anti-cancer treatment, the Homeopathic Clinic of Lucca collaborated with the oncology department of the the Health Unit Toscana North West Lucca and set up an Integrative Oncology Outpatient Unit in the Public Hospital Campo di Marte. Aim: The purpose of this study was to present the results of the homeopathic and complementary integrative medicine treatment targeted at reducing the adverse effects of anti-cancer therapy and cancer symptoms, and to give dietary and lifes [...] 2441 23004 |
Homeopathy and Cancer – Some Conceptual IssuesAbstract
This paper explores some of the conceptual issues that arise when comparing homeopathy with the mainstream medical system, both in terms of their underpinning philosophies and in their treatment methods, and especially when applied to the problem of cancer. A review is under-taken of the key concepts that underpin both medical approaches: the holistic approach of homeopathy and the reductionist approach of mainstream medicine. The article closes with a discussion of the emerging conflicts between classical homeopat [...] 2436 38640 |
The Four-Facet Model of Eudaimonic Resilience and Its Relationships with Mindfulness, Perceived Stress and ResilienceAbstract
Elevated levels of psychological distress in university students is a growing area of concern as it is associated with a variety of consequences including mental illness symptoms, absenteeism, and poor academic performance. A growing body of research has indicated that resilience in university students is associated with reduced psychological distress and perceived stress. The construct of resilience and the factors that contribute to its development are not well understood, hampering the development of effective i [...] 1873 11515 |
Emotional Freedom Techniques for Food Cravings in Overweight Adults: A Comparison of Treatment Lengthby
Peta Stapleton
and
Hannah Chatwin
Abstract
(1) Background: Because patients vary in their response to treatment, including adherence, the effect of treatment length in the use of EFT on food cravings was examined by comparing two studies in order to ascertain if shorter programs are as effective. This may then impact treatment adherence and completion. (2) Methods: In study one, 96 overweight and obese adults were randomly allocated to a 4-week treatment for their food craving or waitlist condition. In study two, an 8-week EFT program for 47 adults, the sam [...] 2103 11159 |
Living with Spondylolisthesis with (Relative) EquanimityAbstract
Objectives: Living with any chronic pain condition is a challenge that can be met when one reduces reactivity to the sensory and evaluative aspects of it. The aim of this case study is to show how a clinical psychologist with expertise in chronic illness applied Buddhist principles to her own experience.
Methods: When one realizes that suffering is the combination of pain plus resistance then one can learn how to accept rather than exacerbate it. Applying the Four Noble Truths from Buddhist psychology to understand [...] 1900 9765 |
Auricular Interventions in Neurology: the Vascular Autonomic Signal ChallengeAbstract
The Auricular approach to diagnostics and therapeutics has gained momentum over the last 15 years. Battlefield Acupuncture has taken on a life of its own and has been adopted into NATO and even been introduced into neonatal intensive care. It is time to take on the challenge of Auricular Medicine - the application of the neurophysiological phenomenon referred to as the Vascular Autonomic Signal or VAS to identify active ear sites in Auricular interventions. It is time to utilize the VAS in therapeutics, recognizing [...] 2252 13070 |
The Efficacy of Mindfulness-Based Interventions on Depressive Symptoms and Quality of Life: A Systematic Review of Randomized Controlled Trialsby
Jonathan Manh Dang
,
Luma Bashmi
,
Stephen Meeneghan
,
Janet White
,
Rebecca Hedrick
,
Jelena Djurovic
,
Brigitte Vanle
,
Dennis Nguyen
,
Jonathan Almendarez
,
Paula Ravets
,
Yasmine Gohar
,
Sophia Hanna
,
Itai Danovitch
and
Waguih William IsHak
Abstract
Background: An increasing number of patients and practitioners are using mindfulness meditation programs despite uncertainty about the evidence supporting these programs’ health benefits. Aim: To review the current evidence on the effectiveness of mindfulness-based interventions (MBI) on depressive symptoms and quality of life (QOL) among patients with depression comorbid medical conditions and those with major depressive disorder. Methods: A comprehensive search of PubMed, Ovid MEDLINE, and PsycINFO was performed [...] 2154 12612 |
A Multi-modal Intervention after Stroke: The Caregiver Experienceby
Katie M. Hinsey
,
Karen E. Atler
,
Christine A. Fruhauf
,
Ruby A. Bolster
,
Marieke Van Puymbroeck
and
Arlene A. Schmid
Abstract
Background: A fall prevention intervention was delivered to people with chronic stroke (Merged Yoga and Occupational Therapy intervention-MY-OT). All caregivers were invited to also attend the 8-week intervention and were included in these analyses. Methods: The aim of this study was to examine changes in caregiver burden, positive aspects of caring, and caregiver's experiences after participating in the MY-OT intervention. This was a secondary data analyses and the purpose of this mixed-methods study was to quanti [...] 1949 10439 |
Healthcare Clowning: Use of Specific Complementary and Alternative Medicine for Hospitalized ChildrenAbstract
Clowning has a varied tradition and a long history. Recently, clowns have been adopted in the medical setting with the aim of decreasing the negative emotions that can be experienced during hospitalization and medical procedures, as well as inducing positive feelings in patients, their relatives, and the hospital staff. Due to an increase in the number of clowns working in hospitals and the large amount of interest shown in utilizing this approach, an increasing number of studies have focused on testing the efficac [...] 2305 13906 |
Dietary Supplements in Dyslipidemiaby
Emily Gutierrez
and
Yousef Elyaman
Abstract
Lifestyle and dietary interventions can have a significant impact on patients with dyslipidemia and should be encouraged with the use of dietary supplements. With new research, there is evidence that using dietary supplements, specifically nutraceuticals can be helpful for cholesterol management. Four commonly used supplements are: Red Yeast Rice, Omega 3 Fatty Acids, Niacin and Berberine. 1826 9341 |
Leveraging Mindfulness to Build Resilience and Professional Quality of Life in Human Service Professionalsby
Andrew Hanna
and
Aileen M. Pidgeon
Abstract
Objective: Mindfulness-based interventions (MBIs) have shown promise in cultivating resilience and are widely accepted as efficacious in the treatment of a range of psychological disorders. This paper explores the feasibility of a Mindful-Awareness and Resilience Skills Training (MARST) program to enhance mindfulness and resilience, as a means of increasing psychological well-being and alleviating burnout and compassion fatigue in human service professionals. Method: In this randomised control trial, 46 human servi [...] 2264 16462 |
Mindfulness Meditation in College Students to Advance Health EquityAbstract
Purpose: High levels of mindfulness correspond with some positive health behaviors such as exercise participation, fruit and vegetable intake, and effective stress management. This study provided mindfulness meditation during an academic semester to a group of predominantly minority college students derived from a population in which 77.9% of the students are considered economically disadvantaged, to assess the effects of mindful meditation on various health behaviors and mindfulness to combat avoidable health ineq [...] 2001 12927 |
How Can Acupuncture Be Used in Treating Dementia?Abstract
Background: Dementia erodes the quality of life of patients and their caregivers, and the growing dementia population threatens public finance in the health and social services. In addition to formal medical treatments, complementary and alternative medicine is applicable to dementia, in which acupuncture has become an option for prevention, remedy, and rehabilitation. Acupuncture is a traditional Chinese medical method that uses needle penetration at acupoints (specific points throughout the body which will be sti [...] 2228 12731 |
Application of Additive Homeopathy in Cancer PatientsAbstract
Oncology patients often suffer from the side-effects of conventional therapy, such as chemotherapy, radiation and/or surgery. Additive complementary medicine, such as homeopathy might be beneficial in the support of these patients. Several case reports as well as some studies have suggested the beneficial effects of homeopathy in cancer patients. Furthermore, homeopathy may also be helpful in improving quality of life (QoL). Homeopathic remedies also offer the advantage that they can be combined with a variety of c [...] 1871 10005 |
Miraculous Healings of Chronic Lyme disease, Fibromyalgia and Sarcoidosis without the Use of Pharmaceuticals or AntibioticsAbstract
While “miraculous healings” of various disease states have been scientifically reported previously, the exact mechanism, which allow for these seeming miracles or spontaneous remissions is poorly understood. [1,2,3,4,5,6,7,8,9,10,11,12,13,14,15] By contrast, the mechanism of action underlying the “miraculous healings” in the three case studies reported herein: Sarcoidosis, Chronic Lyme disease and Fibromyalgia seems to be understood with greater clarity, as these case reports are representative of the many hundreds [...] 2204 21967 |
Obesity and Non-Alcoholic Fatty Liver - Therapies in Ayurvedic MedicinesAbstract
Ayurveda is an ancient Indian medicinal practice. The present review includes translational research characterizing obesity, non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH).
We reviewed published research on improving function through Ayurvedic medicine by searching electronic databases (Medline, Embase) using terms such as: Ayurveda, obesity, NAFLD, NASH, the effect of exercise interventions in obesity, change in body composition. We aim to (1) determine the immuno-pathology of [...] 2110 20468 |
Open Dialogue and the Impact of Therapist Mindfulness on the Health of ClientsAbstract
The value of mindfulness for clinical staff in the mental health field has thus been increasingly recognised over recent year and thus is now culminating in the evaluation and, potential future role out, of whole system approaches like Open Dialogue that put clinician mindfulness at the heart of the model. It is anticipated that this will ultimately be for the benefit of both staff and clients of these services alike, creating improvements and improving lives, therefore, on many levels. 1982 9031 |
Auricular MedicineAbstract
The treatment by auricular therapy has a long history. Ear acupoint research has been advancing step by step worldwide [1-17] . The introduction of lasers into medicine brought besides the already existing stimulation with needles, electricity, pressure and liquids an additional technique to auricular acupuncture. 1790 9351 |
Spirituality in Medical AcupunctureAbstract
Spirituality may be generally conceptualized as the precious, personal path of our apparently soulful vital energy within the context of the power of our compassionate consciousness. The body, mind and spirit encompasses a constantly inspiring vital energetic field that must be in diligent interaction and harmony in the interest of past, present and future generations. In the clinical application of the healing arts and sciences, as physicians or other dedicated health care providers of whatever nation, race, cultu [...] 1841 8666 |
Healthcare-Related Qigong for the Prevention of Lifestyle-Related Diseasesby
Fengxia Liang
,
Qi Huang
,
Rui Chen
,
Song Wu
,
Gary Lu
,
Jianmin Liu
,
Jia Li
,
Lu Wang
,
Hua Wang
and
Gerhard Litscher
Abstract
Qigong is a form of traditional Chinese exercise combining breathing, movement, and meditation to improve fitness for the purpose of preventing disease and prolonging life. We review the clinical efficacy and underlying mechanism of the application of Qigong in the healthcare setting. In addition, we discuss topics such as the impacts on respiratory, cardiovascular function, and immune function, as well as studies of the influences on brain function and mental health. In summary, there is strong evidence of the cli [...] 2085 12789 |
Modulation of Excitability of Spinal Neural Functions by Acupoint Stimulation Physical Therapy at LU5 (Chize) in Three Hemiplegic Patients with Cerebrovascular DiseaseAbstract
(1) Background: Acupoint stimulation physical therapy (ASPT) is a novel method of physical therapy that combines physical and acupuncture methods. This study aimed to examine the effect of ASPT in three hemiplegic patients with cerebrovascular disease using F-wave as a measure of the excitability of spinal neural function.
(2) Methods: Subjects included three hemiplegic patients with cerebrovascular disease who presented with three types of neurological findings. All patients had moderate hypertonic muscles on the [...] 1658 9118 |
Effects of Acupuncture at the Left Weizhong Acupoint on Heart Rate Variability in Thirty Post-Stroke Patients—Results from a Transcontinental Teleacupuncture Studyby
Bo Pang
,
Qi Zhang
,
Guang-Yu Cheng
,
Wei-Ping Cheng
,
Daniela Litscher
,
Lu Wang
,
Zemin Sheng
,
Ingrid Gaischek
,
Zhong-Ren Sun
and
Gerhard Litscher
Abstract
(1) Background: Within this study, we assessed the effects of acupuncture on heart rate variability (HRV) in Chinese post-stroke patients.
(2) Methods: In 30 Chinese post-stroke patients (14 f, 16 m; mean age ± SD 64.3 ± 3.8 years; range 40 - 80 years) electrocardiographic signals before, during and after acupuncture at the left Weizhong acupoint (BL40) were recorded in Harbin and analyzed in Graz using teleacupuncture via internet. HRV data were analyzed in the time and frequency domain and a protoco [...] 1650 9271 |
Modernization of Acupuncture Education in Europe and China: A Report from Austriaby
Daniela Litscher
and
Gerhard Litscher
Abstract
The present report deals with some current important aspects of traditional Chinese medicine (TCM) education and practice in Europe and China. The data and facts are based on a lecture of one of the authors (G.L.) prepared for a conference in Wuhan about acupuncture education in Europe, and lectures of two high-ranking representatives of renowned Chinese institutions (State Administration of TCM and Heilongjiang University of Chinese Medicine, Harbin). In addition to current figures regarding TCM in general, the ad [...] 2165 24139 |
ICM-OBM—There’s No Better Way to Publish Your Complementary Medical, Basic and Clinical Research ResultsAbstract
Integrative and Complementary Medicine (ICM-OBM) is an international peer-reviewed, open-access journal which covers all evidence-based scientific studies on integrative and complementary approaches to improving health and quality of life.
Integrative and complementary medicine comprises science-oriented “university” or academic medicine, but also experience-based medicine with all its complementary methods. It is not a special field in itself, but a signal for an all-encompassing medicine, open-minded about the p [...] 1590 9987 |
Piperine: A Savor Inducer and a Cancer ReducerAbstract
Spices have been used for many decades, and although new and improved culinary spices have been developed, black pepper (Piper nigrum) continues to retain its distinguished title as the “King of spices” due to its particular pungent taste. An alkaloid called piperine is the main component in black pepper that, besides generating the well-known taste, imparts well-documented immunomodulatory, anti-inflammatory, antimicrobial, antioxidant, and even anti-cancer properties; these properties have led to rigorous researc [...] 1065 8467 |
Gastro-Esophageal Reflux in the Newborn: Pathologic Event or Does Spit Happen?Abstract
Infants admitted to Neonatal Intensive Care Units (NICUs) are among the most vulnerable patients in medicine and are at risk for a variety of morbidities, many of which require pharmacologic therapy. Gastroesophageal Reflux Disease (GERD) is a common diagnosis in the NICU patient population and may or may not represent a truly pathologic process. Regardless, pharmacologic therapy is provided to many infants, who are already exposed to an inordinate number of pharmacologic agents, of which most are off label and hav [...] 1167 8443 |
Non-Celiac Gluten Sensitivity in Children: Controversial Role of Gluten and Diagnostic EnigmaAbstract
Non-celiac gluten sensitivity (NCGS) is a debatable condition that affects less than 6% of children. The absence of specific diagnostic markers and standardized diagnostic procedures make the diagnosis of NCGS challenging, covering patients with different and varied symptoms. Generally, the parents of small and younger children introduce a gluten-free diet (GFD) based on their personal experiences and expectations. Additionally, a “fad component” exists, contributing to the recent rise in the popularity of GFD. Thu [...] 1274 5676 |
The Timing of Endoscopic Evaluation of Anti-TNFα Therapy Patients with Ulcerative Colitisby
Hiroyuki Kashiwagi
,
Ayumi Ito
,
Harutaka Kambayashi
,
Shun Murasugi
,
Teppei Omori
,
Maria Yonezawa
,
Shinichi Nakamura
and
Katsutoshi Tokushige
Abstract
Anti-TNFα Therapy are used to induce remission and as maintenance therapy in refractory ulcerative colitis (UC) to achieve mucosal healing (MH). However, the time at which mucosal healing should be assessed is unclear. We retrospectively examined the optimal timing for colonoscopy and the criteria to determine the need for the continuation of treatment. We evaluated 44 UC patients that were treated with anti-TNFα Therapy and categorized them into the following groups according to the degree of MH within 12 months: [...] 1025 5503 |
Varicella-Zoster Gastritis in a Liver Transplant Patient: A Call to Attentionby
Víctor Escrich
,
Angela Martinez Herreros
,
Berta Lapeña
,
Marta Mayorga
,
Antonio Cuadrado
,
Javier Crespo
and
Emilio Fabrega
Abstract
The reactivation of the Varicella-zoster virus (VZV) is a rare cause of acute gastritis in adults. About 30 cases have been reported in the literature, mostly with immunocompromised patients and mainly after bone marrow transplantation or during the development of malignant hematological diseases. Clinically, it is usually accompanied by cutaneous manifestations. Here, we studied a case of VZV gastritis in a liver transplant (LT) patient. We described the main symptoms, endoscopic findings, histologic changes, and [...] 1178 5622 |
The Effects of Mediterranean Diet on the Human Gut Microbiota; a Brief Discussion of Evidence in HumansAbstract
The Mediterranean diet (MD) is considered one of the healthiest dietary patterns due to its rich provision of phytochemicals, antioxidants, vitamins, fiber, polyunsaturated, omega-3, and short-chain fatty acids through a variety of foods. The supply of such nutrients and bioactive components can support gut health and reduce systemic inflammation, with accumulating evidence from several human studies demonstrating the utility of the Mediterranean diet in the prevention of chronic and metabolic diseases. Further stu [...] 1395 8033 |
Deconstructing then Priming Gut Microbiota ResilienceAbstract
The human intestinal microbiota represents a complex microbial community that plays an essential role in the maintenance of host health. Over the last decade, metagenomic and metabolomic analyses have revealed the influence of intestinal microbial diversity and composition on a range of biological functions in the host. While overall taxonomic composition of the intestinal microbiome is informative, changes in spatial dynamics within the community also have profound biological significance as microbial functions ar [...] 1391 8286 |
Acknowlegement to Reviewers of OBM Hepatology and Gastroenterology in 2020Abstract
The editors of OBM Hepatology and Gastroenterology would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2020. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers receive a voucher entitling them to a discount on their next LIDSEN publication and can download a certificat [...] 1109 5783 |
Multi-Species Probiotic Modulates Cytokine Production and the Interplay between Immune and Colon Cancer CellsAbstract
The current study aimed to investigate the effect of a multi-species probiotic (MSP) on cytokine production by human peripheral blood mononuclear cells (PBMCs) and their immune dialogue with HT-29 colon cancer cells. PBMCs were incubated with MSP and their effect on cell proliferation and TNFα, IL-1β, IL-2, IL-6, IFNγ, IL-10, and IL-1ra production was evaluated. The impact of MSP on the cytokine production by PBMC stimulated by HT-29 cells was detected. Not-stimulated PBMC incubated with MSP showed increased produc [...] 1413 7592 |
The Physiology of Esophageal Reflexesby
Ivan M. Lang
Abstract
Several digestive tract reflexes involving the esophagus and its sphincter muscles have been identified, but to date, no comprehensive review has addressed most of these reflexes. The current review presents the known physiology of different esophageal reflexes in which either the esophagus or its sensory or motor portion of the reflex response is elaborated. The current review comprehensively examines the known and possible mechanisms underlying major esophageal reflexes, highlights the huge gaps in current knowle [...] 2250 8918 |
Porto-Sinusoidal Vascular Disease with Obliterative Portal Venopathy Associated with Long-Term Azathioprine for Crohn’s DiseaseAbstract
Patients receiving immunosuppressive therapy for inflammatory bowel disease may be susceptible to non-cirrhotic portal hypertension, now referred to as porto-sinusoidal vascular disease. Here we describe a patient treated with long-term azathioprine for Crohn’s disease who developed porto-sinusoidal vascular disease with obliterative portal venopathy without nodular regenerative hyperplasia on histology. Specific signs of portal hypertension were present, including porto-systemic collaterals on imaging. Histopathol [...] 1569 8129 |
Human Gut Microbiota: Friend or Foe?by
Monika Pliszka
and
Leszek Szablewski
Abstract
The human gut is a house to approximately 1,000 different species of bacteria. The bacterial composition of gut microbiota is influenced by several factors, including age, sex, mode of delivery, geographical location, ethnicity, diet, drugs, and administration of prebiotics and/or probiotics. Similarly, human health depends on the composition of gut microbiome, with gut bacteria playing a crucial role in human physiology. For instance, gut microbiota synthesizes vitamins and amino acids, and affects the biotransfor [...] 1559 8598 |
Use of Organs from Hepatitis C Viremic Donors: Addressing the Needs of a Changing Waitlist and the Effect of a Public Health CrisisAbstract
The combination of broad screening initiatives and development of effective antiviral therapies have led to a revolution in the treatment of hepatitis C virus and has reduced the proportion of patients with the virus who develop a need for liver transplantation in favor of other etiologies, such as alcohol-related liver disease and non-alcoholic steatohepatitis. However, the opioid epidemic and rise in injection drug use in the United States has simultaneously led to otherwise healthy hepatitis C viremic patients d [...] 1486 6732 |
Prevalence of Chronic Constipation and Irritable Bowel Syndrome, and their Overlap, among Female Undergraduate Students in Japanby
Katsuhisa Omagari
,
Risa Kumamoto
,
Yuko Koyama
,
Masako Suzuta
,
Asami Taniguchu
,
Ayumi Fukuda
,
Momoe Iwami
,
Kazunori Koba
,
Asako Kawaguchi
and
Kazunori Otsuka
Abstract
Chronic constipation and irritable bowel syndrome (IBS) are two of the most common functional gastrointestinal disorders, both of which negatively affect the quality of life of the patients. Since people may have co-existing symptoms of multiple disorders, chronic constipation and IBS with predominant constipation cannot be clearly distinguished. In this cross-sectional study, data were obtained from self-administered questionnaires to assess the prevalence of chronic constipation and IBS, and their overlap, among [...] 1335 8078 |
Association between Sleep Deprivation and Metformin Treatment on Pancreatic and Liver Function in MiceAbstract
Metformin has been widely used as a therapeutic drug for hyperglycemia and diabetes. Sleep is a vital and restorative process that is necessary for the proper functioning of organs. Sleep deprivation can induce multi-organ injury, including damage to the pancreas and liver that may result in hyperglycemia and diabetes. We studied the role of metformin in reversing sleep deprivation-induced hyperglycemia and pancreatic and liver dysfunction in mice. Mice were kept in cages and fed water and food ad libitum. Mice wer [...] 1408 8997 |
Can HCV Viremic Organs Be Used in Liver Transplantation to HCV Negative Recipients?by
Haris Muhammad
,
Muhammad Hammami
,
Peng-sheng Ting
,
Cem Simsek
,
Behnam Saberi
and
Ahmet Gurakar
Abstract
Liver transplantation has steadily increased worldwide resulting in a large number of patients on the waiting list. Due to the opioid epidemic in the US, the pool of Hepatitis C seropositive donors increased significantly in recent years. Direct acting antivirals played an instrumental role in making liver transplantation with hepatitis C positive allograft an acceptable option. Although hepatitis C positive liver transplantation to hepatitis C positive recipients is a common practice, there is limited data and agr [...] 1445 7458 |
Low Prevalence of Spontaneous Bacterial Peritonitis in Ambulatory Asymptomatic Cirrhotic Patients: Consequences in Patients’ CareAbstract
The literature on the prevalence of spontaneous bacterial peritonitis (SBP) in cirrhotic outpatients who visited the hospital for therapeutic abdominal paracentesis was reviewed in order to assess the usefulness of urinary strips in this setting. The authors reviewed the studies published as peer-reviewed articles on the prevalence of SBP in ambulatory outpatients who visited the hospital for therapeutic paracentesis. Five such studies were available in the literature. It was found that the prevalence of SBP was in [...] 1231 6750 |
Endoscopic Therapy for Recurrent Acute PancreatitisAbstract
Recurrent acute pancreatitis (RAP) is a clinical entity characterized by episodes of acute pancreatitis which occurs on more than one occasion. Recurrence of pancreatitis generally occurs in a setting of a normal anatomical and functional gland, however, a chronic disease at early stage may be found either on the occasion of the first episode of pancreatitis or during the follow-up. The etiology of RAP can be identified in up to 70% of cases; for the remaining cases the term “idiopathic” is used. Most common caus [...] 1397 7728 |
The Daclatasvir/Asunaprevir/Beclabuvir Combination Therapy for Chronic Hepatitis C Patients Experiencing Failure of IFN-Free DAA-Based Therapiesby
Ken Sato
,
Atsushi Naganuma
,
Shuichi Saito
,
Yuichi Yamazaki
,
Takeshi Kobayashi
,
Hiroki Tojima
,
Norio Horiguchi
,
Satoru Kakizaki
,
Toshio Uraoka
,
Hiroshi Ohnishi
and
Hiroaki Okamoto
Abstract
Background: Daclatasvir/asunaprevir/beclabuvir (DCV/ASV/BCV) combination therapy had been available for the treatment of chronic hepatitis C patients with genotype 1 (CHG1) in Japan. Our aim was to report the efficacy and safety of DCV/ASV/BCV in patients experiencing treatment failure with interferon (IFN)-free direct-acting antiviral agent (DAA)-based therapies, which have not been fully evaluated.
Methods: We evaluated the efficacy and safety of 12-week DCV/ASV/BCV combination therapy for CHG1 patients experien [...] 1307 7940 |
Hypereosinophilia with Gastrointestinal Involvement: A Case ReportAbstract
Hypereosinophilic syndrome is currently defined by an absolute blood eosinophil count of more of 1500 cell per μL for more than 1 month and by multiorgan system infiltration.
Eosinophilic colitis is an exceptionally rare inflammatory condition in which eosinophils infiltrate the colonic gut. It represents the least frequent manifestation of the wide spectrum of eosinophilic gastrointestinal disorders.
We describe a case of an adult male patient with persistent eosinophilia for at least twenty-five years. During thi [...] 1475 9529 |
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