Optimizing Psychopharmacotherapy Using Personality Biomarkers: A Seven-Factor Model Perspective
Abstract
Optimizing Psychopharmacotherapy Using Personality Biomarkers: A Seven-Factor Model PerspectiveAbstract Personalized psychopharmacotherapy remains a critical yet underdeveloped frontier in psychiatry, as traditional approaches often fail to address substantial interindividual variability in drug efficacy and tolerability. While demographic, clinical, and genetic factors have improved treatment precision, they do not fully account for observed heterogeneit [...] |
Promising Electrocatalytic Systems 2,5-di-Me-Pyrazine-di-N-Oxide - Cyclohexanol - Single-Walled and Multi-Walled Carbon Nanotubes for the Simultaneous Metal-Free Oxidation of Cyclohexanol at Anode and Release of Hydrogen Evolution at Cathodeby
Abstract Electrocatalytic oxidation of organic compound in the absence of noble metals or their oxides as catalysts and using metal-free electrodes is a "green" electrochemical, inexpensive and attractive process for practical use in electrocatalysis, power sources and sensors. The process accompanied by the elimination of protons, is of interest both for obtain [...] |
Movement-informed Breathwork (MiB): Integrating Muscular Contractions with Slow Conscious Connected Breathing for Therapeutic ApplicationAbstract This paper introduces Movement-informed Breathwork (MiB), a personalised breath-body approach with biofeedback that integrates a form of conscious connected breathwork (breathing without pauses) with targeted neuromuscular contraction and relaxation cycles. Drawing from neuromuscular torque chain dynamics, fascial research and sensorimotor trauma therap [...] |
Balancing Preservation and Maximizing Utilization: A DCD Lung Procurement Strategy During Abdominal Normothermic Regional Perfusionby
Abstract The increasing demand for organ transplantation has necessitated innovative strategies to maximize donor organ utilization, especially in donation after circulatory death (DCD) contexts. This article explores the integration of direct lung recovery with abdominal normothermic regional perfusion (A-NRP) to optimize organ preservation and expand the donor [...] |
Evidence for an Impact of Super Skills for Life on Emotional and Behavioral Difficulties in Greek Anxious ChildrenAbstract Super Skills for Life (SSL) is a transdiagnostic psychoeducational program designed for children with anxiety and depressive symptoms based on cognitive-behavioral therapy. Empirically documented studies to date have demonstrated its immediate and long-term effectiveness in different contexts. The aim of this study was to assess the efficacy of the [...] |
Machine Perfusion in DCD Lung Transplantation: Advances in Preservation and Donor Pool Expansionby
Abstract To address the pressing shortage of donor lungs, Donation after Circulatory Death (DCD) transplantation has become a vital strategy for expanding the donor pool. Minimizing warm ischemic injury is crucial for optimizing organ viability and function. This review synthesizes current evidence on Normothermic Regional Perfusion (NRP) and Ex-Vivo Lung Perfus [...] |
Stem Cell-Derived Exosomes: Non-Coding RNA Cargos for Reprogramming the Tumor Immune Microenvironmentby
Abstract Stem cell-derived exosomes (SDEs) have emerged as revolutionary mediators in cancer immunotherapy, offering unprecedented potential to reprogram the immunosuppressive tumor immune microenvironment (TIME). These nano-sized extracellular vesicles, laden with non-coding RNAs (ncRNAs), serve as natural biocompatible carriers, capable of orchestrating immune [...] |
Contribution of Solar Energy to Buildings’ Energy Demands: A Reviewby
Abstract Buildings account for a significant portion of global energy consumption, estimated at 30-40%, and also contribute to greenhouse gas emissions. Energy consumption in a building is mainly thermal (natural gas) and electrical. This energy is usually used for heating water, cooking, illumination, ventilation and air conditioning, powering appliances, floor [...] |
Genetic Differentiation of Populations of Three Megalopolises by DNA Markers of the Y-Chromosome in Connection with the Problem of Developing Genetic DatabasesAbstract The purpose of the study was to consider the distribution of Y-chromosome DNA markers in samples from the populations of the three largest megalopolises (Moscow, Saint Petersburg, and Novosibirsk) in the Russian Federation, in the context of developing genetic databases. The study aimed to compare the frequency profiles of 18 Y-chromosome STRs (Short [...] |
Valorization of Agro-Industrial Residues into Furfural via Catalytic Pyrolysisby
Abstract Pyrolysis is a promising technology for converting biomass waste into bio-oil, a liquid product that can serve as feedstock for fuels and high-value chemicals. In this study, bio-oil was produced via catalytic pyrolysis of pear pulp waste, a byproduct from juice and jam manufacturing, using a fixed-bed reactor. Initial non-catalytic experiments were [...] |
An Exploration of the Experiences of Group Compassion Focused Therapy for Hospital Outpatients with Long-Term Mental Health Difficultiesby
Abstract There is now good evidence for the efficacy of Compassion Focused Therapy (CFT) for a variety of mental health difficulties. To deepen understanding of the processes underpinning CFT’s effectiveness, this service evaluation explored the experiences and reflections of individuals with long-term mental health difficulties who had previously received [...] |
Integrating Small-Scale Geothermal into a Mini-Grid to Improve Electricity Access in NigeriaAbstract Increasing local energy access in developing countries, particularly in off-grid regions where mini-grids are often overloaded, remains a critically underexplored area in energy transition. These regions often face significant technical and economic challenges, such as low generation capacity, high energy costs, limited energy access, and heavy reliance [...] |
Genetic and Clinical Features of Tuberous Sclerosis Patients from the Republic of BashkortostanAbstract Tuberous sclerosis (TS) is one of the most common hereditary tumor syndromes, occurring with an average incidence of 1 in 9,000 newborns worldwide. The disease manifests itself through the development of tumors of the brain, kidneys, heart, lungs, and skin, along with characteristic depigmented spots. Tuberous sclerosis is caused by germline variants [...] |
iRest™ Meditation Webinar Series Addresses Depression Symptoms in Older Adultsby
Abstract Older adults in the U.S. have higher rates of depression, stress, and chronic diseases. There is an urgent need for effective interventions to reduce depressive symptoms and enhance overall health and well-being. Meditation presents an appealing therapeutic option due to its cost-effectiveness, minimal risks, ease of use, and active patient involvement [...] |
Acupuncture’s Effects on Intracranial Pressure: From Early Observations to Modern InsightsAbstract Understanding whether acupuncture can influence intracranial pressure (ICP) and cerebral hemodynamics remains a relevant and insufficiently explored question in contemporary neurovascular research. This editorial synthesizes early experimental observations with recent clinical and technological advances to reassess the cerebral effects of acupuncture [...] |
The Role of Nitrogen-Containing Compounds in Chemical Neuroscience: Implications for Drug Developmentby
Abstract The study explores the crucial biological function of nitrogen in cyclic and acyclic structures with resonance potential, including tetrazoles, pyrroles, piperidines, and carbamates, within the realm of chemical neuroscience. It highlights the importance of these compounds for their biological properties and their ability to cross the blood-brain barrie [...] |
Acknowledgment to Reviewers of OBM Genetics in 2025Abstract The editors of OBM Genetics would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2025. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication [...] |
Acknowledgment to Reviewers of OBM Integrative and Complementary Medicine in 2025Abstract The editors of OBM Integrative and Complementary Medicine would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2025. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of [...] |
Acknowledgment to Reviewers of OBM Neurobiology in 2025Abstract The editors of OBM Neurobiology would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2025. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication [...] |
Acknowledgment to Reviewers of Journal of Energy and Power Technology in 2025Abstract The editors of Journal of Energy and Power Technology would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2025. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which [...] |
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