OBM Geriatrics is an Open Access journal published quarterly online by LIDSEN Publishing Inc. The journal takes the premise that innovative approaches – including gene therapy, cell therapy, and epigenetic modulation – will result in clinical interventions that alter the fundamental pathology and the clinical course of age-related human diseases. We will give strong preference to papers that emphasize an alteration (or a potential alteration) in the fundamental disease course of Alzheimer’s disease, vascular aging diseases, osteoarthritis, osteoporosis, skin aging, immune senescence, and other age-related diseases.
Geriatric medicine is now entering a unique point in history, where the focus will no longer be on palliative, ameliorative, or social aspects of care for age-related disease, but will be capable of stopping, preventing, and reversing major disease constellations that have heretofore been entirely resistant to interventions based on “small molecular” pharmacological approaches. With the changing emphasis from genetic to epigenetic understandings of pathology (including telomere biology), with the use of gene delivery systems (including viral delivery systems), and with the use of cell-based therapies (including stem cell therapies), a fatalistic view of age-related disease is no longer a reasonable clinical default nor an appropriate clinical research paradigm.
Precedence will be given to papers describing fundamental interventions, including interventions that affect cell senescence, patterns of gene expression, telomere biology, stem cell biology, and other innovative, 21st century interventions, especially if the focus is on clinical applications, ongoing clinical trials, or animal trials preparatory to phase 1 human clinical trials.
Papers must be clear and concise, but detailed data is strongly encouraged. The journal publishes research articles, reviews, communications and technical notes. There is no restriction on the length of the papers and we encourage scientists to publish their results in as much detail as possible.
Archiving: full-text archived in CLOCKSS.
Publication Speed (median values for papers published in 2022): Submission to First Decision: 5 weeks; Submission to Acceptance: 14 weeks; Acceptance to Publication: 11 days (1-2 days of FREE language polishing included)
Happy People Live Longer: Positive Well‐Being Contributes to Health and Longevity
Submission Deadline: July 01, 2022 (Open) Submit Now
Dr. Alex Bishop, Associate Professor
Oklahoma State University, Stillwater, OK, USA
Research Interests: Connection between distal and proximal life experiences; Well-being of persons living 100+ years; Interplay of social and religious/spiritual resources on the physical and mental well-being of aging prisoners
About the topic:
The aim of this special issue to encourage scientists to publish conceptual, theoretical, and empirical results surrounding the interplay of happiness, health, and longevity. Of particular preference are papers that focus on old-old adults, particularly centenarian populations, and emphasize fundamental life-span processes and life-course mechanisms that contribute to positive longevity including happiness, gratitude, life satisfaction, optimism, meaning and purpose in life and the will-to-live; biopsychosocial indicators of positive well-being and healthy longevity; and genetic biomarkers of positive longevity which contribute to the avoidance, delay, or survivorship of physical and mental health impairments among individuals and/or their successive family members. Papers that are clear and concise yet provided detailed data are strongly encouraged. There are no length restrictions of papers, and we encourage scientists to publish their result with as much detail as possible.
Age-associated diseases; Biomarkers; Biopsychosocial; Centenarians; Cognitive health; Dying and death; Exceptional longevity; Family heredity; Family; Longevity; Gratitude; Happiness; Healthy longevity; Human longevity; Life course; Life-satisfaction; Life-span; Longevity genes; Meaning-in-life; Mental health; Old-old; Oldest old; Optimism; Positive aging and longevity; Quality-of-life; Sense of purpose; Physical health impairment; Successful aging and longevity; Survivorship; Terminal drop; Wellness; Will-to-live
Received: 01 July 2022; Published: 14 November 2022; doi: 10.21926/obm.geriatr.2204211
This research aims to examine cross-sectional and longitudinal associations of positive subjective well-being among centenarians and near-centenarians in the Health and Retirement Study. Participants who eventually survived to age 98 or older (N = 516) were included. Study variables included demographic characteristics [...]
Living in an Age of Longevity: Enduring Insights and Perspectives for Embarking on a Quest for Health and Well-Being in Later Life
Received: 01 August 2021; Published: 15 March 2022; doi: 10.21926/obm.geriatr.2201195
While increases in life expectancy along with extended longevity can be seen as a success story, there remains the central issue surrounding the health and quality of life for increasing numbers of older people. As populations live longer the idea that older people should be empowered to remain active and productive citizens will [...]
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