OBM Geriatrics is an Open Access journal published quarterly online by LIDSEN Publishing Inc. The journal takes the premise that innovative approaches – including gene therapy, cell therapy, and epigenetic modulation – will result in clinical interventions that alter the fundamental pathology and the clinical course of age-related human diseases. We will give strong preference to papers that emphasize an alteration (or a potential alteration) in the fundamental disease course of Alzheimer’s disease, vascular aging diseases, osteoarthritis, osteoporosis, skin aging, immune senescence, and other age-related diseases.

Geriatric medicine is now entering a unique point in history, where the focus will no longer be on palliative, ameliorative, or social aspects of care for age-related disease, but will be capable of stopping, preventing, and reversing major disease constellations that have heretofore been entirely resistant to interventions based on “small molecular” pharmacological approaches. With the changing emphasis from genetic to epigenetic understandings of pathology (including telomere biology), with the use of gene delivery systems (including viral delivery systems), and with the use of cell-based therapies (including stem cell therapies), a fatalistic view of age-related disease is no longer a reasonable clinical default nor an appropriate clinical research paradigm.

Precedence will be given to papers describing fundamental interventions, including interventions that affect cell senescence, patterns of gene expression, telomere biology, stem cell biology, and other innovative, 21st century interventions, especially if the focus is on clinical applications, ongoing clinical trials, or animal trials preparatory to phase 1 human clinical trials.

Papers must be clear and concise, but detailed data is strongly encouraged. The journal publishes a variety of article types (Original Research, Review, Communication, Opinion, Comment, Conference Report, Technical Note, Book Review, etc.). There is no restriction on the length of the papers and we encourage scientists to publish their results in as much detail as possible.

Publication Speed (median values for papers published in 2023): Submission to First Decision: 5.7 weeks; Submission to Acceptance: 17.9 weeks; Acceptance to Publication: 7 days (1-2 days of FREE language polishing included)

Current Issue: 2024  Archive: 2023 2022 2021 2020 2019 2018 2017

Special Issue

Happy People Live Longer: Positive Well‐Being Contributes to Health and Longevity

Submission Deadline: July 01, 2022 (Open) Submit Now

Guest Editor

Dr. Alex Bishop, Associate Professor

Oklahoma State University, Stillwater, OK, USA

Website1 | Website2 | E-Mail

Research Interests: Connection between distal and proximal life experiences; Well-being of persons living 100+ years; Interplay of social and religious/spiritual resources on the physical and mental well-being of aging prisoners

About the topic:

The aim of this special issue to encourage scientists to publish conceptual, theoretical, and empirical results surrounding the interplay of happiness, health, and longevity. Of particular preference are papers that focus on old-old adults, particularly centenarian populations, and emphasize fundamental life-span processes and life-course mechanisms that contribute to positive longevity including happiness, gratitude, life satisfaction, optimism, meaning and purpose in life and the will-to-live; biopsychosocial indicators of positive well-being and healthy longevity; and genetic biomarkers of positive longevity which contribute to the avoidance, delay, or survivorship of physical and mental health impairments among individuals and/or their successive family members. Papers that are clear and concise yet provided detailed data are strongly encouraged. There are no length restrictions of papers, and we encourage scientists to publish their result with as much detail as possible.


Age-associated diseases; Biomarkers; Biopsychosocial; Centenarians; Cognitive health; Dying and death; Exceptional longevity; Family heredity; Family; Longevity; Gratitude; Happiness; Healthy longevity; Human longevity; Life course; Life-satisfaction; Life-span; Longevity genes; Meaning-in-life; Mental health; Old-old; Oldest old; Optimism; Positive aging and longevity; Quality-of-life; Sense of purpose; Physical health impairment; Successful aging and longevity; Survivorship; Terminal drop; Wellness; Will-to-live

Manuscript Submission Information

Manuscripts should be submitted through the LIDSEN Submission System. Detailed information on manuscript preparation and submission is available in the Instructions for Authors. All submitted articles will be thoroughly refereed through a single-blind peer-review process and will be processed following the Editorial Process and Quality Control policy. Upon acceptance, the article will be immediately published in a regular issue of the journal and will be listed together on the special issue website, with a label that the article belongs to the Special Issue. LIDSEN distributes articles under the Creative Commons Attribution (CC BY 4.0) License in an open-access model. The authors own the copyright to the article, and the article can be free to access, distribute, and reuse provided that the original work is correctly cited.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). Research articles and review articles are highly invited. Authors are encouraged to send the tentative title and abstract of the planned paper to the Editorial Office (geriatrics@lidsen.com) for record. If you have any questions, please do not hesitate to contact the Editorial Office.

Welcome your submission!


Open Access Original Research

Active Aging for L.I.F.E.: An Intergenerational Program for Addressing and Changing Attitudes Toward Longevity

Received: 19 July 2022;  Published: 27 December 2023;  doi: 10.21926/obm.geriatr.2304264


The global population of adults 65 years of age and older will increase dramatically over the next several decades, presenting economic and social challenges requiring sustainable solutions. Aging is a process in which everyone is already involved, it is a lifelong experience not just a later life occurrence. Changing world demogra [...]
Open Access Original Research

Happy and Satisfied in Very Late Life? Findings from the Health and Retirement Study

Received: 01 July 2022;  Published: 14 November 2022;  doi: 10.21926/obm.geriatr.2204211


This research aims to examine cross-sectional and longitudinal associations of positive subjective well-being among centenarians and near-centenarians in the Health and Retirement Study. Participants who eventually survived to age 98 or older (N = 516) were included. Study variables included demographic characteristics [...]
Open Access Review

Living in an Age of Longevity: Enduring Insights and Perspectives for Embarking on a Quest for Health and Well-Being in Later Life

Received: 01 August 2021;  Published: 15 March 2022;  doi: 10.21926/obm.geriatr.2201195


While increases in life expectancy along with extended longevity can be seen as a success story, there remains the central issue surrounding the health and quality of life for increasing numbers of older people. As populations live longer the idea that older people should be empowered to remain active and productive citizens will [...]