The Role of Nitrogen-Containing Compounds in Chemical Neuroscience: Implications for Drug Development
by
Ferydoon Khamooshi
,
Samaneh Doraji-Bonjar
,
Ali Reza Modarresi-Alam
and
Mohammad Hasan Mohammadi
Abstract
The study explores the crucial biological function of nitrogen in cyclic and acyclic structures with resonance potential, including tetrazoles, pyrroles, piperidines, and carbamates, within the realm of chemical neuroscience. It highlights the importance of these compounds for their biological properties and their ability to cross the blood-brain barrier (BBB) to reach the central nervous system (CNS). The study emphasizes the necessity for neurochemical drugs, like morphine, to effectively cros [...]