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Open Access Original Research

Estimating Inhaled Nitrogen Dioxide from the Human Biometric Response

Received: 19 December 2023;  Published: 08 May 2024;  doi: 10.21926/aeer.2402011

Abstract

Breathing clean air is crucial for maintaining good human health. The air we inhale can significantly impact our physical and mental well-being, influenced by parameters such as particulate matter and gases (e.g. carbon dioxide, carbon monoxide, and nitrogen dioxide). Building on previous research that explored the effects of particulate matter (PM) in specific environments, analyzed using biometric indicators and machine learning models; this work focuses on the effects and estimation of inhaled nitrogen dioxide ( [...]

1210 6486

Open Access Original Research

Determining the Contribution of Physical Activity Constructs in Developing Intention to Exercise among Entrepreneurs

Received: 08 January 2024;  Published: 06 May 2024;  doi: 10.21926/obm.neurobiol.2402222

Abstract

In the present era, a healthy life is a challenge for everyone. Therefore, diverting individuals' minds towards physical activity and exercise is necessary for the day. This paper proposes to inspect the impact of physical activity on the development of intention to exercise (ITE) among entrepreneurs. The quantitative study collected data from 383 Egyptian entrepreneurs through a survey questionnaire. Most respondents were males (n = 257 or 67.10%) against females (n = 126 or 32.90%). The range of age of the respon [...]

1413 6906

Open Access Original Research

Mental Health of Teachers during the First Wave of COVID-19 in Daegu, Korea: Challenges in Reopening Schools

Received: 25 February 2024;  Published: 06 May 2024;  doi: 10.21926/obm.neurobiol.2402221

Abstract

This study conducted an in-depth analysis of the psychological states of teachers during the first outbreak of coronavirus disease 2019 (COVID-19) using data on school mental health projects related to COVID-19 in Daegu from May to June 2020. The participants comprised 811 (34.9%) male and 1,511 (65.1%) female teachers in 1,041 (44.8%) middle and 1,281 (55.2%) high schools. After schools reopened, the most common causes of unbearable stress were unusual experiences, fear of infection, and negative emotions. Moreove [...]

1246 7586

Open Access Original Research

Enhancing Thermal, Viscoelastic, and Mechanical Properties of Silicone Rubber Matrix through Reinforcements for Use as a Medical Implant

Received: 14 December 2023;  Published: 03 May 2024;  doi: 10.21926/rpm.2402011

Abstract

The use of silicone rubber as an implant is limited due to its weak properties. In this study, the impact of various reinforcements, such as TiO2 or SiO2 nanoparticles, carbon, or polypropylene fiber micro reinforcements, on the mechanical, thermal, and viscoelastic properties of silicone rubber composites with RTV-4125 matrix was investigated. The composites were evaluated through several tests, including tensile, compression, FTIR, TGA, DMTA, and water adsorption tests. It was found that the composites' tensi [...]

2298 14781

Open Access Original Research

The Impact of Stress on Father Involvement in Early Infancy: Examining Risk and Protective Factors in Residential and Nonresidential Fathers

Received: 24 December 2023;  Published: 30 April 2024;  doi: 10.21926/obm.icm.2402025

Abstract

Residential and nonresidential fathers are taking an increasingly greater role in their children’s lives, and father involvement predicts positive child outcomes across development. This study utilized data from a large sample of racially and ethnically diverse fathers of low to middle income (n = 1,112) to test if paternal stress is associated with lower father involvement in early infancy and whether perceived social support is protective. Exploratory analyses examined whether the effects of stress on father invo [...]

1613 13726

Open Access Review

Induced Mutagenesis using Gamma Rays: Biological Features and Applications in Crop Improvement

Received: 24 December 2023;  Published: 29 April 2024;  doi: 10.21926/obm.genet.2402233

Abstract

Induced mutagenesis has emerged as an essential field of plant breeding to address global food security challenges, offering tools to enhance crop productivity, resistance, and nutritional value. Among the mutation induction tools, the physical mutagen such as gamma rays holds promise for efficient mutation induction. Gamma rays, a type of high-energy electromagnetic radiation, possess unique characteristics that enable them to penetrate plant tissues and induce genetic mutations. The biological effects are influen [...]

3728 36791

Open Access Review

Salinity Stress in Maize: Consequences, Tolerance Mechanisms, and Management Strategies

Received: 04 December 2023;  Published: 29 April 2024;  doi: 10.21926/obm.genet.2402232

Abstract

Maize, along with rice and wheat, is a popular staple food crop worldwide, and the most widely produced cereal crop. It is a versatile crop that may be utilized as a source of raw materials for human and animal fodders. Low agricultural yield and rapid population expansion significantly threaten future food security. Maize production is hampered by biotic and abiotic causes, with abiotic factors being the most critical limitation to agricultural output worldwide. Soil salinity is a key abiotic factor that reduces a [...]

2839 24013

Open Access Original Research

Low Mortality Associated with COVID-19 Infection in Lung Transplant Recipients at a Single Center

Received: 15 October 2023;  Published: 28 April 2024;  doi: 10.21926/obm.transplant.2402213

Abstract

Lung Transplant Recipients (LTR) are particularly vulnerable to severe infection, hospitalization, and death due to community acquired respiratory viruses. As a result, the global SARS-Cov-2 pandemic poses a higher risk to this population. We aim to study the lung function, severity of infection and mortality among LTR at a single center. A retrospective chart review was performed on all LTR at the University of San Diego, California Medical Center between June 2020 and September 2022. Spirometry was performed at 1 [...]

1003 5705

Open Access Original Research

Understanding Mental Health Needs and Predictors of Anxiety in Emirati Female Students in Higher Education

Received: 09 November 2023;  Published: 28 April 2024;  doi: 10.21926/obm.neurobiol.2402220

Abstract

The prevalence rates of depression, anxiety, and stress range between 5% to 70% globally. Many students experience these mental health conditions as they go through transitional periods in life, such as starting higher education. This study aimed to explore mental health concerns, specifically depression, anxiety, stress, and quality of sleep, in Emirati female university students, a topic that has been understudied in the Middle East. We used the Depression, Anxiety, and Stress Scales (DASS-21) and the Pittsburgh [...]

1356 10702

Open Access Original Research

Unveiling Genetic Variation in Garlic Genotypes in Response to Rust Disease Using RAPD Markers

Received: 23 January 2024;  Published: 28 April 2024;  doi: 10.21926/obm.genet.2402231

Abstract

Garlic (Allium sativum), cultivated worldwide for its medicinal and nutritional value, faces challenges due to diseases caused by various pathogens. In this study, eleven garlic genotypes from Iran and one from China were selected and sown under natural infection rendered by the rust fungus (Puccinia alli) over two consecutive years. Subsequently, disease distribution and severity, percentage of infection and susceptibility of different garlic genotypes to rust disease were investigated. The results showed that gen [...]

1399 6772

Open Access Concept Paper

Compassion-Focused Mentoring: An Antidote to Adverse Faculty-Student Mentoring Outcomes?

Received: 14 October 2023;  Published: 27 April 2024;  doi: 10.21926/obm.icm.2402024

Abstract

Fueled by decreased state support, economic pressures, and a growing emphasis on academic capitalism, higher education in the United States faces significant challenges. These shifts have fostered fast-paced, competitive environments, impacting the quality and equity of faculty-student mentoring in graduate programs, particularly for Black, Indigenous, People of Color (BIPOC), and first-generation students. This article proposes a novel framework, the compassion-focused mentoring conceptual model (CFM-CM), to addre [...]

1425 7411

Open Access Original Research

The Acceptability and Impact of a Video on Compassion Focused Therapy as a Psycho-Educative Tool to Deepen Awareness around Voice-Hearing

Received: 21 December 2023;  Published: 25 April 2024;  doi: 10.21926/obm.icm.2402023

Abstract

In the compassion focused therapy (CFT) model of voice-hearing, a distressing relationship with voices is thought to be influenced by evolved threat-protection patterns, which are activated and attuned by socially threatening experiences, such as being harmed by others, as well being shamed, stigmatised, invalidated, and excluded. Therefore, the CFT approach is particularly interested in the role of voice-hearers’ relationships with others and self, as well as their social context of family/friends, professio [...]

1233 8061

Open Access Original Research

The Impact of Physical Activity on Brain Neuroplasticity, Cognitive Functions and Motor Skills

Received: 20 December 2023;  Published: 25 April 2024;  doi: 10.21926/obm.neurobiol.2402219

Abstract

The research aims to study the mechanisms and factors contributing to brain neuroplasticity. To achieve this goal, the following methods were used: analysis and synthesis, hermeneutic method, psychological testing, and comparative and generalization methods. The research results revealed the nature of the concept of brain neuroplasticity and types of neuroplasticity, analyzed the process of redistribution of brain functions, determined the role of compensatory plasticity, revealed methods of studying brain neuropla [...]

1936 28282

Open Access Review

Molecular Plant Physiology for Model Plants under Abiotic Stress Conditions

Received: 23 December 2023;  Published: 24 April 2024;  doi: 10.21926/obm.genet.2402230

Abstract

Extreme temperatures, drought, and high soil salinity are some of the significant abiotic stresses that can severely impact crop yields, posing a threat to global food production. Comprehensive studies on model plant species are crucial for understanding their biochemical, physiological, and molecular responses to abiotic stresses. Identifying stress response mechanisms and potential targets can aid in developing stress-tolerant crop varieties. Additionally, elucidating the functions of reactive oxygen species is e [...]

1470 10028

Open Access Editorial

Nutritional Guidance for Individuals with Prediabetes — Uniform or Tailored to Phenotypes?

Received: 15 April 2024;  Published: 23 April 2024;  doi: 10.21926/rpn.2402008

1301 5510

Open Access Original Research

Contribution of a Single Islet Transplant Program to Basic Researchers in North America, Europe, and Asia through Distributing Human Islets

Received: 23 February 2024;  Published: 23 April 2024;  doi: 10.21926/obm.transplant.2402212

Abstract

There has been a steady expansion in islet isolation and transplantation activity worldwide. In addition to preparing human islets for transplantation, we have been providing human islets to basic researchers. The aim of this study was to review the activity of distribution of human islets to basic researchers in North America, Europe, and Asia, and to investigate if there are any differences in utilization rate of islets among three continents. We reviewed our islet isolation batch files, donor records, and docume [...]

1129 7657

Open Access Original Research

Oleuropein can Protect the Brain Against Deleterious Effects of Bile Duct Ligation in Male Mice

Received: 26 December 2023;  Published: 23 April 2024;  doi: 10.21926/obm.neurobiol.2402218

Abstract

Oleuropein (OP) is a phenolic compound in olives. OP possesses potent antioxidant activity and an extensive spectrum of other pharmacological properties, including antiviral, anti-inflammatory, and antimicrobial activities. This study investigated the effects of OP on neural injuries caused by bile duct ligation (BDL) in male mice. The mice were randomly allocated to three groups: sham, BDL, and BDL + OP. Neurobehavioral tests histological and biochemical evaluations were accomplished to assess cerebral damage. The [...]

1225 5295

Open Access Case Report

Sun Safety Struggles Among Children with Xeroderma Pigmentosum in a Tropical Low-Income Country

Received: 05 February 2024;  Published: 19 April 2024;  doi: 10.21926/obm.genet.2402229

Abstract

Xeroderma pigmentosum (XP) is a rare genodermatosis characterized by increased sensitivity to ultraviolet radiation, leading to severe skin manifestations and a higher risk of early-onset malignancies. Previous studies from temperate climate countries with sound economic levels showed adequate photoprotection compliance among pediatric XP patients. However, no studies have assessed photoprotection compliance among children with XP living in tropical and low-economic settings. This article reports a low photoprotect [...]

1155 6460

Open Access Original Research

Coliform Bacteria Contamination of Water Resources and Implications on Public Health in Fako Division, South West Region, Cameroon

Received: 03 March 2024;  Published: 19 April 2024;  doi: 10.21926/aeer.2402010

Abstract

Bacteriological contamination of water sources, often due to improper handling of human waste, poses significant public health risks. This study investigates coliform bacteria contamination in water sources across the Fako Division of Cameroon. Twenty water samples were collected from various sources, including streams, community water, springs, boreholes, and wells, and analyzed for total coliforms using Violet-Red-Bile-Lactose (VRBL) Agar. Additionally, 352 household questionnaires were administered in four towns [...]

2681 15944

Open Access Short Communication

Home-Based Appetite-Guided Weaning of Enteral Nutrition of Infants with Congenital Heart Disease: A Preliminary Clinical Observation

Received: 13 January 2024;  Published: 19 April 2024;  doi: 10.21926/rpn.2402007

Abstract

Infants with a critical congenital heart defect are at high-risk for feeding difficulties, often necessitating feeding tube placement. Enteral nutrition (EN) support is initiated to meet nutritional requirements and promote growth pre- and post-operatively. Tube-fed infants with congenital heart disease (CHD) who achieve stable health status post-operatively are at risk of becoming feeding tube dependent (FTD). We report a clinical observation for infants with CHD based on survey results from Growing Independent Ea [...]

1950 10197

Open Access Review

Newborn Screening for Neuromuscular Disorders, Disorders of Glycogen Metabolism, and Fatty Acid Oxidation

Received: 08 February 2024;  Published: 18 April 2024;  doi: 10.21926/obm.genet.2402228

Abstract

Newborn screening for neuromuscular disorders and glycogen or fatty acid oxidation disorders aims to identify infants at risk for these conditions, allowing for early intervention and management. While not all neuromuscular disorders currently have established newborn screening programs, there are various disorders for which screening is available or under investigation. Neuromuscular disorders encompass a wide range of conditions that affect the nerve, muscle, or the connection between them. Examples include spina [...]

1299 5846

Open Access Research Article

Characteristics of Elder Abuse Perpetrators by Sexual Orientation and Gender Identity of the Abused: Findings from the Canadian Longitudinal Study on Aging

Received: 20 December 2023;  Published: 16 April 2024;  doi: 10.21926/obm.geriatr.2402278

Abstract

Lesbian, gay, and bisexual (LGB) older adults may be more vulnerable to elder abuse (EA) due to prior marginalization and trauma, lifelong discrimination, and health disparities. While characteristics of both victims and perpetrators can modify the risk for EA, few studies have focused on perpetrators. This study examined the number and type of perpetrator-victim relationships and perpetrator profiles for EA experienced in the prior year, by abuse type and sexual orientation and gender identity of the abused. Data [...]

1333 9099

Open Access Original Research

A Comprehensive in Silico Analysis of the Functional and Structural Consequences of the Deleterious Missense Nonsynonymous SNPs in Human GABRA6 Gene

Received: 20 December 2023;  Published: 15 April 2024;  doi: 10.21926/obm.genet.2402227

Abstract

Epilepsy, a prevalent neurological disorder, affects more than 50 million individuals worldwide and is characterized by recurring seizures. Nonsynonymous single nucleotide polymorphisms (nsSNPs) found within coding regions of epilepsy-related genes are believed to have significant impacts on protein function. This is due to their tendency to cause mutations in the encoded amino acids, which can subsequently lead to pathogenic alterations in protein structure and function. Consequently, nsSNPs have the potential to [...]

1211 7850

Open Access Original Research

Dietary Fiber in Preventing Non-Communicable Diseases: Predicting Prevented Deaths and Economic Impact through the Use of Algae as a Fiber Source

Received: 30 August 2023;  Published: 15 April 2024;  doi: 10.21926/rpn.2402006

Abstract

Non-communicable diseases (NCDs) are responsible for two-thirds of premature deaths in Europe. This added to the European socio-economic scenario already weakened by the vital aging of the population, contributes to the loss of active individuals, weakening competitiveness and social and economic sustainability, thus making the prevention of NCDs a European objective. Preventing NCDs with the enrichment of the food environment using algae or their compounds, which are rich in nutrients and bioactivities, is an exce [...]

1627 7721

Open Access Perspective

Whisker Bond: From Findings to Concept in Refractories

Received: 12 January 2024;  Published: 12 April 2024;  doi: 10.21926/rpm.2402010

Abstract

Ceramic bonds are conventionally formed during the burning of refractory bricks and by using pre-fabricated blocks or monolithic lining, which is characterized as the coalescence of the particles by liquid sintering. However, the whisker bond was discovered with the outstanding performance of unburnt periclase–spinel–Al bricks while substituting magnesia–chrome bricks in the chromium-free campaign of refractory lining of RH degassers. Thanks to the prominent effect of the whisker bond, such a refr [...]

1367 6363

Open Access Original Research

Chest CT Scan Features of COVID-19 in a Hospitalized High-Altitude Population

Received: 30 November 2022;  Published: 12 April 2024;  doi: 10.21926/obm.genet.2402226

Abstract

There is a lack of knowledge regarding the type of lung compromise in high-altitude residents with COVID-19. This study aims to evaluate the lung compromise in chest CT scans of high-altitude dwellers hospitalized with COVID-19. Retrospective study that took place in "Daniel Alcides Carrión" Regional Hospital, located 3,250 meters above sea level in the city of Huancayo, Perú. 464 medical charts and chest CT images of hospitalized patients with confirmed COVID-19 from January to March 2021 were reviewed. The mean a [...]

1044 5094

Open Access Original Research

Compassionate Love for a Romantic Partner among Brazilian College Students

Received: 08 February 2024;  Published: 12 April 2024;  doi: 10.21926/obm.neurobiol.2402217

Abstract

Compassionate love (CL) is a recent subject of close relationships. CL is focused on enlarging beneficence to another. The present study approaches the test of the psychometric characteristics of the shortened form of the Compassionate Love Scale for a partner (CLS-P-SF) for Brazilian college students and its relationships with background and well-being variables. The sample included 217 young adults, 46.1% women and 53.9% men. Confirmatory factor analysis revealed that the single latent factor of the CLS-P-SF is g [...]

1487 6635

Open Access Review

Thrombotic Microangiopathy in Solid Organ Transplantation

Received: 31 January 2024;  Published: 10 April 2024;  doi: 10.21926/obm.transplant.2402211

Abstract

Thrombotic Microangiopathy (TMA) is a syndrome characterized by microangiopathic hemolytic anemia (MAHA) and thrombocytopenia. The presence of schistocytes on peripheral smear, a negative Coombs test, elevated lactate dehydrogenase, increased reticulocyte count and low haptoglobin are often the clues for MAHA. The microvascular process often targets vasculature in kidneys, brain, gastrointestinal system, heart, and skin. A timely diagnosis and treatment are often crucial to prevent severe end organ damage and death [...]

2765 15187

Open Access Original Research

Attitudes and Motivations Towards Implantation of Intention Towards Exercise among Entrepreneurs: A Brain Freshness Activity

Received: 19 October 2023;  Published: 10 April 2024;  doi: 10.21926/obm.neurobiol.2402216

Abstract

In the contemporary landscape, developing individuals' attitudes, motivations, and intentions toward exercise and physical activities emerges as an imperative cornerstone for fostering a healthy and thriving lifestyle. The present study examines the effect of the theory of the planned behavior (TPB) constructs on exercise motivation (MT) and intention towards exercise (ITWE) among Egyptian entrepreneurs. The study employed a quantitative approach and collected cross-sectional responses from entrepreneurs throug [...]

1175 5799

Open Access Review

Allelic Variation of High-Molecular-Weight Glutenin Genes in Triticum Species and Triticale (× Triticosecale Wittmack)

Received: 27 February 2024;  Published: 09 April 2024;  doi: 10.21926/obm.genet.2402225

Abstract

High-molecular-weight glutenin subunits (HMW-GS) encoded by alleles at the Glu-A1, Glu-B1, and Glu-D1 loci confer unique bread-making properties of common wheat (Triticum aestivum L.). The identification of HMW-GS is the prerequisite for pyramiding high-quality glutenin genes. The present review is designed to list all published HMW-GS alleles in Triticum species and triticale (A- and B genomes), focusing on methods for their identification. T. monococcum is characterized by 37 alleles at the Glu-1 locus versus fou [...]

1500 7306

Open Access Book Review

Book Review: Small Supernumerary Marker Chromosomes. Basics

Received: 21 February 2024;  Published: 09 April 2024;  doi: 10.21926/obm.genet.2402224

Abstract

This review provides a critical assessment of the content and structure of the recently published book by Dr. Thomas Liehr, 'Small Supernumerary Marker Chromosomes: Basics.'

937 4224

Open Access Review

Osteoporosis Etiology, Epidemiology, Diagnosis, Diet, and Treatment: A Narrative Review

Received: 26 December 2022;  Published: 09 April 2024;  doi: 10.21926/obm.geriatr.2402277

Abstract

This narrative review aimed to select, gather, and present inclusive evidence about osteoporosis etiology, epidemiology, diagnosis, diet, and treatment. We searched PubMed and Google using these terms: osteoporosis AND etiology, osteoporosis AND epidemiology, osteoporosis AND diagnosis, osteoporosis AND diet, and osteoporosis AND treatment. Each title of the extracted manuscripts was read first. If deemed suitable, the abstracts of the manuscripts and text were read carefully. Afterward, the details of each term we [...]

3390 28850

Open Access Editorial

Solid Catalysts – New Perspectives and Applications

Received: 31 March 2024;  Published: 09 April 2024;  doi: 10.21926/cr.2402004

1519 7679

Open Access Review

Andropause: A Neglected Disease Entity

Received: 11 January 2024;  Published: 03 April 2024;  doi: 10.21926/obm.geriatr.2402276

Abstract

This review aims to bring attention to the growing issue of andropause, a condition that affects men as they age. The literature was identified by searching the major bibliographic databases, including PubMed, Google Scholar, EBSCOhost, Web of Science, and CINAHL. Studies were included if they focused on strategies for reducing and preventing andropause, published between 1980 and 2023. Andropause, which is often overlooked and misconceived, is the result of a decrease in testosterone production and can result in p [...]

2997 70581

Open Access Review

“Guess Who?” in the Creation of Hazardous and Non-Hazardous Diets through History

Received: 17 November 2023;  Published: 03 April 2024;  doi: 10.21926/rpn.2402005

Abstract

The relationship between obesity and weight loss treatments has run parallel throughout history; however, not all diets are suitable for improving one’s health. This review aims to categorize diets according to the new classification of hazardous diets established in 2021. A search was conducted across grey, white, and black literature. The results reveal a study of 179 diets, of which 35 are effective, while the rest are hazardous to health. Looking at the geographical distribution of these diets, the USA, the UK, [...]

1353 9786

Open Access Review

Review on the Development of Titanium Diboride Ceramics

Received: 02 January 2024;  Published: 03 April 2024;  doi: 10.21926/rpm.2402009

Abstract

Titanium diboride (TiB2) materials have garnered significant attention due to their remarkable comprehensive properties. They offer potential applications in high-temperature structural materials, cutting tools, armor, electrodes for metal smelting, and wear-resistant parts. However, due to the low self-diffusion coefficient, the TiB2 exhibits poor sinterability, excessive grain growth at elevated temperatures, and inadequate oxidation resistance, limiting its wide application. Therefore, many research works are de [...]

3915 23868

Open Access Perspective

Leveraging Existing Abilities in Dementia (LEAD™): Changing the Way Rehabilitation Professionals Care for Persons Living with Dementia

Received: 08 December 2023;  Published: 03 April 2024;  doi: 10.21926/obm.geriatr.2402275

Abstract

Latest estimates indicate that 5-7% of the population are living with Alzheimer’s disease and related dementias worldwide with a doubling in incidence expected every 20 years. Rehabilitation professionals are challenged with the complex needs of these patients. It is commonly thought that patients with dementia do not benefit from rehabilitation because of cognitive decline, behaviors, lack of communication, or difficulties in learning; however, current literature indicates this is not accurate. With proper knowled [...]

1499 8389

Open Access Editorial

Acupuncture in Oncology – Update 2024

Received: 02 April 2024;  Published: 03 April 2024;  doi: 10.21926/obm.icm.2402022

Abstract

Acupuncture, as a promising complementary therapy for cancer patients, offers personalized symptom management and improved quality of life alongside conventional treatments. With its proven efficacy in alleviating chemotherapy-induced side effects such as nausea, fatigue, and pain, acupuncture stands as a holistic approach to cancer care. Tailored to individual needs and boasting a favorable safety profile, acupuncture addresses both physical symptoms and psychological distress, promoting resilience and quality of [...]

1338 10266

Open Access Original Research

Design and Techno-Economic Evaluation of a Hybrid Mini-grid System for an Academic Institution

Received: 26 September 2023;  Published: 03 April 2024;  doi: 10.21926/jept.2402010

Abstract

Inadequate electricity supply is a global challenge that needs solutions. This situation has compelled the purchasing of fossil fuel-generating units for use in residential, commercial, and industrial sectors to generate electricity. However, using fossil fuel generating units cause greenhouse gas emissions, bringing about environmental pollution and ultimately resulting in climate change. In particular, educational institutions require adequate and reliable power supply to ensure proper learning and teaching, whic [...]

2005 11866

Open Access Research Article

Local Authority Waste Management Strategies, the Circular Economy and the Generation of Energy from Waste in England

Received: 17 February 2024;  Published: 01 April 2024;  doi: 10.21926/jept.2402009

Abstract

The purpose of this article is to examine the approach to waste management of local authorities in England, to investigate their strategic objectives, and to ascertain to what extent sustainability and circular economy practices are in evidence in this context. A qualitative, inductive research method is used, based on an examination of secondary documentation in three local authorities in England in Birmingham, Bristol and Newcastle upon Tyne. The findings reveal considerable common ground within the three authori [...]

1322 8002

Open Access Review

Management of Steatosis in Living Donors: Where Do We Stand?

Received: 23 October 2023;  Published: 01 April 2024;  doi: 10.21926/obm.transplant.2402210

Abstract

With the progressive rise in rates of liver transplantation, stagnant donor pool, and social factors, living donor liver transplantation (LDLT) forms the majority of liver transplantations performed in Asian countries. As the global prevalence of metabolic-associated fatty liver disease (MAFLD) is increasing, around 17-25% of all the prospective donors turn out to be steatotic at the time of evaluation and, as such, rejected for donor hepatectomy, thereby considerably reducing the living donor pool. Steatotic graft [...]

1092 7137

Open Access Review

Airway Complications after Lung Transplantation

Received: 12 September 2023;  Published: 27 March 2024;  doi: 10.21926/obm.transplant.2401209

Abstract

Lung transplantation in patients with end stage lung disease can improve survival and quality of life. Airway complication incidence varies between 2-33%, but the true incidence is difficult to determine due to a lack of validated classification systems. There are many risk factors for post lung transplant airway complications, the most common being anastomotic ischemia, pulmonary infections, surgical technique and allograph dysfunction. Common complications include formation of granulation tissue, anastomotic sten [...]

1398 8948

Open Access Original Research

“Seeing Myself Through Someone Else’s Eyes”: Embodying the Perfect Nurturer in Compassion Focused Therapy

Received: 29 January 2024;  Published: 27 March 2024;  doi: 10.21926/obm.icm.2401021

Abstract

Compassion-focused chairwork has become a recent focus of empirical investigation. This study extended this area of research by exploring how participants with depression experienced the ‘compassionate other’ imagery exercise enacted via chairwork methods. Eight individuals from primary care NHS mental health services were interviewed about their experience of the practice. The resultant data were analysed using interpretive phenomenological analysis (IPA). Three group experiential themes were identified: care that [...]

1532 9797

Open Access Review

Potential of Nutritious Indian Medicinal Plants to Boost Immunity in the Aftermath of Pandemics: A SWOC Analysis

Received: 23 August 2023;  Published: 26 March 2024;  doi: 10.21926/rpn.2401004

Abstract

The world has suffered a lot during the COVID-19 pandemic, for which nobody was prepared. Due to the lack of appropriate treatment, Indian medicinal plants have alleviated the burden due to their diverse health benefits. It has been observed that certain medicinal plants can effectively enhance immunity against microorganisms and viruses. Numerous scientific studies have supported the above claims. This paper presents the SWOC analysis of Indian medicinal plants for their immunity-enhancing effects so that the medi [...]

1520 8049

Open Access Short Report

The Heavy Burden of Judgement: Cultivating Compassion with People Accessing Healthcare Services for Support with Weight Management

Received: 16 October 2023;  Published: 20 March 2024;  doi: 10.21926/obm.icm.2401020

Abstract

Compassion focused therapy concepts and techniques are explored in the context of weight management efforts within community, specialist and surgical settings. Living at higher weights within a culture that over-values life at low weights can induce feelings of shame, self-loathing and hypercriticism. This article examines points at which individuals engaging in weight management may experience heightened distress and describes some of the ways that the model has been applied with this population. An outline of the [...]

1067 6520

Open Access Short Review

Postoperative Cognitive Dysfunction and Virtual Reality for Cognitive Rehabilitation in Cardiac Surgery Patients: A Short Review

Received: 02 November 2023;  Published: 19 March 2024;  doi: 10.21926/obm.neurobiol.2401215

Abstract

Postoperative cognitive dysfunction (POCD) has been observed as a complication after cardiac surgery consistently. The ineffectiveness of current treatments for POCD is causing a search for non-invasive alternatives. The present review aims to consolidate the current understanding of how VR methods effectively facilitate the recovery of cognitive functioning in cardiac surgery patients. To obtain information about the effects of VR technology on cognitive functions, we investigated the PubMed, Scopus, and Web of Sc [...]

1436 6353

Open Access Short Report

X Ray-Induced Insulinoma Cell Line Rin-5F Has a Novel Mutation Site, C.A1459G (P.T487A), in Death Domain Associated Protein (DAXX) Gene

Received: 05 January 2024;  Published: 19 March 2024;  doi: 10.21926/obm.genet.2401223

Abstract

A popular toxicological and pharmacological research cell line is the insulin-secreting pancreatic cell line Rin-5F. The cell line originates from insulinomas induced by X-ray exposure. The author of this report looked at the mutation status of the DAXX gene in the Rin-5F cell line clone. The complete DNA and RNA were extracted from the cultivated cells as well. Double-stranded cDNA was then synthesized using the RNA template. Sequencing was done using a 3730xl DNA Analyzer. In the present study, c.A1459G (p.T487A) [...]

978 4676

Open Access Review

Hot Topics on Nutrition in IBD

Received: 04 January 2024;  Published: 19 March 2024;  doi: 10.21926/rpn.2401003

Abstract

Inflammatory bowel diseases (IBD) affect primarily the bowel, but they are multisystemic diseases with a wide range of extraintestinal manifestations and complications. Nutritional imbalance occurs frequently in patients with IBD. The spectrum of malnutrition goes from undernutrition (low protein-caloric intake, disease-related malnutrition, micronutrient deficiencies) to overnutrition and obesity. The nutritional status of patients with IBD is increasingly recognized as a key aspect of the treatment and must be ad [...]

2012 13834

Open Access Research Article

What Do We Know about an Invisible Issue? Results of a Scoping Review of Elder Abuse and Gender and Sexual Minorities

Received: 04 January 2024;  Published: 18 March 2024;  doi: 10.21926/obm.geriatr.2401274

Abstract

Elder abuse occurs to older adults who are members of gender and sexual minorities (GSM). Whilst most of that abuse is similar to that experienced by their heterosexual and cisgender peers GSM older adults face particular vulnerabilities due to their life experiences and changes. In this article we report on our findings from a literature search and knowledge synthesis, conducted as part of a larger project to inform Canadian policy makers working to eliminate gender and sexuality-based inequalities. The review inc [...]

1546 10068

Open Access Review

A Review on Silk Fibers and Their Medical Applications

Received: 12 December 2023;  Published: 15 March 2024;  doi: 10.21926/rpm.2401008

Abstract

This mini-compilation study included the chemical structure, mechanical, thermal, and dimensional properties of silk fiber, its production process, pre-treatment, and biomedical applications from various experimental studies, which are compiled and summarized. The silk fiber should have a degumming process before using biomedical applications. The 25% concentration for Na2CO3 in ethanol solution (80%) as a coagulant chemical with a salt such as LiB2 (9 M) at a temperature of 98°C for 45 minutes at pH between 6 [...]

5246 20005

Open Access Original Research

Wind Farm Layout Optimization Subject to Cable Cost, Hub Height, and a Feasible 3D Gaussian Wake Model Implementation

Received: 06 February 2024;  Published: 15 March 2024;  doi: 10.21926/jept.2401008

Abstract

We address the Wind Farm Layout Optimization (WFLO) problem and tackle the optimal placement of several turbines within a specific (wind farm) area by incorporating additional aspects of an economically driven target function. With this, we contribute three refinements for WFLO research: First, while many research contributions optimize the turbines' locations subject to maximum energy production or energy efficiency, we instead pursue a strategy of maximizing a profit objective. This enables us to incorporate inne [...]

1508 8277

Open Access Research Article

Capillary Suction Properties of Mortar Made with Recycled Plastic Aggregates Elaborated from Waste Electrical and Electronic Equipment

Received: 18 October 2023;  Published: 15 March 2024;  doi: 10.21926/rpm.2401007

Abstract

It is possible to revalue the plastic fraction from WEEE using it as a recycled aggregate (RA) in cement mortars. However, this feasibility depends on elaborating a granular material via a core-shell strategy to stabilize the potential contaminants. The core is a plastic particle, and the shell is a cement, fillers, and activated carbon mixture. Due to the hydrophilic characteristics of the shell and the presence of interstitial sites generated by the use of the RA, it is necessary to study the wetting properties o [...]

994 5411

Open Access Research Article

Effectiveness of Mindfulness-Based Stress Reduction (MBSR) Interventions on Mindfulness and Stress Symptoms for Cancer Patients: A Quantitative Assessment

Received: 21 January 2024;  Published: 13 March 2024;  doi: 10.21926/obm.icm.2401019

Abstract

The aim of this article is to provide a quantitative assessment of the correlation between heightened mindfulness and stress reduction among cancer patients and survivors who engaged in Mindfulness-Based Stress Reduction (MBSR) interventions. Utilizing data from eight studies, we conducted quantitative analyses to provide the effectiveness scores of MBSR interventions on mindfulness, assessed using the Mindful Attention Awareness Scale (MAAS), and stress symptoms, evaluated through standardized self-reported questi [...]

1324 11048

Open Access Case Report

Management of Posttraumatic Cerebrospinal Fluid Leak with Secondary Diffuse Pneumocephalus Complicated by Meningitis and Communicating Hydrocephalus – Illustrative Case Report

Received: 10 January 2024;  Published: 13 March 2024;  doi: 10.21926/obm.neurobiol.2401214

Abstract

Rhinorrhea is a possible complication after different types of traumatic brain injury or neurosurgical procedures, such as skull base operations. Pneumocephalus is a rarely noted complication after severe traumatic brain injury, and it may be accompanied by meningitis and ventriculitis, especially when treatment has been delayed. Treatment of these entities includes conservative and surgical approaches. Pneumocephalus may result in neurologic disturbances threatening a life. Therefore, active patient management wit [...]

1089 6017

Open Access Correction

Correction: Tse et al. How COVID-19 Ceases All Older Adult Services & the Way Out for Community-Dwelling Older Adults with Chronic Pain. OBM Neurobiology 2023; 7: 183

Received: 11 March 2024;  Published: 12 March 2024;  doi: 10.21926/obm.neurobiol.2401213

Abstract

CorrectionCorrection: Tse et al. How COVID-19 Ceases All Older Adult Services & the Way Out for Community-Dwelling Older Adults with Chronic Pain. OBM Neurobiology 2023; 7: 183Mimi Mun Yee Tse 1, *, Shamay Sheung Mei Ng 2, Vivian Lou 3, Raymond SK Lo 4, Daphne Sze Ki Cheung 5, Paul H Lee 6, Shuk Kwan Tang 7, Siu Hang Leung 1, Percy Poo-See Tse 1* Correspondence: Mimi Mun Yee Tse; E-Mail: mmytse@hkmu.edu.hkAcademic Editors: Ines Testoni, Adriano Zamperini and Lorenza PalazzoSpecial Issue: How COVID-19 Changed Indi [...]

1099 5088

Open Access Review

Impact of Sex and Gender Differences on Heart Failure, Especially in Elderly Patients

Received: 27 December 2023;  Published: 11 March 2024;  doi: 10.21926/obm.geriatr.2401273

Abstract

Heart failure is one of the major health threats in Western societies, and its prevalence is steadily increasing. Many data show the important impact of sex (biological) and gender (sociocultural) differences on most aspects (diagnosis, etiology, treatments, and outcomes) of heart failure. For example, compared to men, women with heart failure are older, have more co-morbidities, and develop different phenotypes of heart failure. Postpartum cardiopathy is unique in women. The iatrogenic effects of cancer therapies [...]

1337 8098

Open Access Communication

Calculated Human Leucocyte Antigens Evolutionary Divergence (cHED)

Received: 15 December 2023;  Published: 11 March 2024;  doi: 10.21926/obm.transplant.2401208

Abstract

Human Leucocyte Antigens (HLA) constitute a highly polymorphic set of genes pivotal to the immune response. The HLA heterozygous advantage hypothesis assumes that heterozygous individuals at the HLA level have a wider range of peptides for T cell recognition than homozygous individuals. Consequently, they possess an enhanced capacity to trigger a targeted immune reaction. The divergent allele advantage hypothesis is an extension of heterozygous advantage, considering the excessive sequence divergence between allele [...]

1152 7224

Open Access Original Research

The Effect of SnO2 and Rh on Pt Nanowire Catalysts for Ethanol Oxidation

Received: 24 November 2023;  Published: 11 March 2024;  doi: 10.21926/cr.2401003

Abstract

In this study, we synthesized Pt-Rh nanowires (NWs) through chemical reduction of metallic precursors using formic acid at room temperature, excluding the use of surfactants, templates, or stabilizing agents. These NWs were supported on two substrates: carbon (Vulcan XC-72R) and carbon modified with tin oxide (SnO2) via the sol-gel method (10 wt.% SnO2). We explored the electroactivity of Pt/SnO2/C, Pt-Rh/C, Pt-Rh/SnO2(commercial)/C (commercial SnO2), and Pt-Rh/SnO2/C NWs toward electrochemical oxidation of ethanol [...]

2266 14951

Open Access Original Research

Resilience in Adversity: COVID-19 Pandemic Challenges in Diminishing Entrepreneurial Intentions and Business Startups

Received: 13 November 2023;  Published: 11 March 2024;  doi: 10.21926/obm.neurobiol.2401212

Abstract

In this study, the researchers explore the effects of COVID-19-related challenges, such as fear and anxiety about COVID-19, the uncertainty of COVID-19, and the recognition of business opportunities for entrepreneurial intentions and business startups. This study used quantitative methods and based their findings on 278 usable samples collected from Egyptian entrepreneurs. Employing the Structural Equation Model (SEM) through SmartPLS4 shows that fear and anxiety arising from the COVID-19 pandemic harm entrepreneur [...]

1367 7594

Open Access Original Research

Preimplantation Genetic Testing: Personal Views Regarding the Invasiveness of Trophectoderm Biopsy and Risks on Embryos Development “An Operators Survey”

Received: 02 January 2024;  Published: 07 March 2024;  doi: 10.21926/obm.genet.2401222

Abstract

This study aims to assess the Trophectoderm (TE) biopsy practice in Jordan in terms of the following effectiveness parameters: timing of zona breaching, risk of inner cell mass herniation if zona breaching was done on day 3, timing of TE sampling, method of biopsy (pulling or flicking), number of laser pulses, assessment of embryo survival after biopsy, and degeneration rate. An online cross-sectional survey was conducted in November 2022. The collected data presented the perception of embryologists (>10 years e [...]

1181 11597

Open Access Review

A Review on Male Infertility and Herbal Medicine: Complementary and Alternative Therapies in Animal Models

Received: 27 September 2023;  Published: 06 March 2024;  doi: 10.21926/obm.genet.2401221

Abstract

Various factors contributing to male infertility include genetic determinants, hormonal/neurological imbalance, erectile/libido disorders, genital tract injuries, and toxic/ischemic testicular injuries. Herbs increase sperm count and quality parameters, as well as sexual performance in infertile men, through various mechanisms. For this purpose, efforts were made to investigate effective plants in treating infertility, focusing on those studied in animal research. In this review, we explored the latest findings fro [...]

2407 16176

Open Access Original Research

Modified Jade Wind-Barrier Formula (MJWB) for Preventing Common Cold in Elderly with Qi-deficiency Constitution: A Controlled Trial

Received: 04 December 2023;  Published: 06 March 2024;  doi: 10.21926/obm.icm.2401018

Abstract

The modified Jade Wind-Barrier formula (MJWB) may prevent the common cold in the elderly with a Qi-deficiency Constitution. Previously, no controlled trial evidence existed to illuminate the concept of “preventive treatment of disease” as outlined in the constitution theory of Traditional Chinese Medicine. This theory distinctly suggests that enhancing the Qi-deficiency Constitution and modulating its functional state can prevent the occurrence of the common cold. This controlled trial (ClinicalTrials.gov identifie [...]

1936 10542

Open Access Research Article

Resilience and Adaptability of Older Adults: Findings from the COVID-19 Impact Survey

Received: 08 January 2024;  Published: 06 March 2024;  doi: 10.21926/obm.geriatr.2401272

Abstract

The COVID-19 pandemic caused abrupt changes in daily routines, social connections, and ways of life. It is yet unknown the full impacts these extended changes have had on the long-term mental well-being of those who shared this global experience. As a contribution to our overall understanding of this phenomena, this study explored the effects of the COVID-19 pandemic on the mental well-being of older adults in the Southern United States. Secondary data analyses were performed using the COVID-19 Emotional Impact Sur [...]

1151 7115

Open Access Case Report

Mosaic Potocki-Lupski Syndrome Due to a Supernumerary Marker Chromosome Containing RAI1

Received: 30 December 2023;  Published: 05 March 2024;  doi: 10.21926/obm.genet.2401220

Abstract

Potocki-Lupski syndrome (PTLS) is a recurrent microduplication syndrome characterized by developmental delay, behavioral abnormalities, mildly dysmorphic facial features, hypotonia, and sleep disorders. We report here a 3-year-old girl diagnosed with mosaic PTLS harboring a supernumerary marker chromosome containing the RAI1 (retinoic acid induced 1) gene. Cytogenetic testing, including chromosomal microarray, karyotype, and FISH analysis, identified a ring chromosome containing portions of chromosomes 14 and 17 in [...]

1331 7006

Open Access Review

Challenges and Opportunities of Gene Therapy in Cancer

Received: 07 October 2023;  Published: 04 March 2024;  doi: 10.21926/obm.genet.2401219

Abstract

Gene therapy involves either the direct introduction of genetic material (DNA or RNA) into the host cell (or organ), known as in vivo gene therapy, the re-introduction of the modified target cells taken out of the host, or ex vivo gene therapy. Cancer is mainly caused by the non-functioning of genes required for normal cell proliferation, and it has emerged as the leading cause of death globally due to the absence of efficient and safe therapies as well as early diagnostic modalities. Therapeutic trials using gene [...]

2859 30238

Open Access Research Article

Investigation of the Effect of Aerosol Deposition by Applying Electrostatic Fields

Received: 07 September 2023;  Published: 01 March 2024;  doi: 10.21926/aeer.2401009

Abstract

Particulate matter (PM) constitutes a significant risk factor for environmental health regarding ambient air quality. An epidemiological investigation has determined that inadequate air quality is associated with the development of lung and cardiovascular diseases, chronic ailments, respiratory infections, and a significant number of fatalities on a global scale. According to the World Health Organization (WHO), the annual mortality rate due to air pollution is around 7 million individuals. The necessity for resear [...]

1293 9913

Open Access Original Research

Covid 19’s Social Quarantine-Moderated Self-Reported Mental Health and Substance Use Among US Adults

Received: 03 December 2023;  Published: 29 February 2024;  doi: 10.21926/obm.icm.2401017

Abstract

In 2019 the novel coronavirus spread quickly throughout the world. It was easily transmitted, resulting in a sudden increase in infection and death rates that overwhelmed hospitals. This sudden pandemic resulted in government and health officials mandating physical and social quarantines to decrease the spread of COVID-19. All these unexpected factors induced traumatic stress across the world. The impact of this trauma is seen to date, as many studies reported adverse mental health effects in an array of population [...]

1160 5337

Open Access Original Research

A Systematic Review about Building Characteristics as Dampness-Related Indicators

Received: 05 October 2023;  Published: 29 February 2024;  doi: 10.21926/aeer.2401008

Abstract

The consistent associations between dampness and health-related problems, such as allergies and asthma symptoms, explain the growing scientific interest in assessing housing characteristics. Due to a growing interest in the built environment, the present study performed a systematic review to investigate the prevalence of dampness related to specific building characteristics. The built environment is gaining significance in population well-being due to the substantial time spent indoors. This aspect is especially n [...]

2974 17239

Open Access Case Report

The Jacobs Syndrome: Clinical Case

Received: 15 October 2023;  Published: 28 February 2024;  doi: 10.21926/obm.genet.2401218

Abstract

This work describes a clinical case of a violation of sex formation in a newborn child with Y-chromosome dysomy. The diagnostic challenges related to Y-chromosome variability and associated anomalies in sex development are being considered. The work presents clinical and laboratory data for Y-chromosome dysomy. It is noted that the challenge in diagnosing disorders of sex development is associated with the polymorphic clinical manifestations of this syndrome. It is noted that the presence of Y-chromosome dysomy is [...]

1533 9334

Open Access Research Article

Exploring Education for Children with 22q11.2 Deletion Syndrome: A Qualitative Study of Mothers Perspectives

Received: 26 September 2023;  Published: 28 February 2024;  doi: 10.21926/obm.genet.2401217

Abstract

22q11.2 deletion syndrome (22q11.2DS) is a complex and widely variable genetic syndrome involving multisystem physical health problems, significant cognitive and psychosocial challenges, all of which may impact upon learning and academic achievement. In the current study, we explored mothers’ perceptions of their child’s learning within early and primary educational contexts. We conducted 3 online focus groups and 1 online semi-structured interview with a total of 9 mothers of children diagnosed with 22q11.2DS. Mot [...]

1548 11011

Open Access Original Research

Molecular Study on Y Chromosome Microdeletion in Male Infertility: A Cross-Sectional Design in Indonesian Men

Received: 09 October 2023;  Published: 27 February 2024;  doi: 10.21926/obm.genet.2401216

Abstract

Y chromosome microdeletions (YCMs) are one kind of genetic disorder that contributes to male infertility. This study aims to determine the profile of YCMs in the infertile male population in Indonesia. This cross-sectional study was conducted by identifying YCMs testing data on 49 infertile male patients identified with azoospermia and oligoasthenoteratozoospermia (OAT) based on their sperm analysis, who visited andrology polyclinics in several hospitals in Yogyakarta Province between March 2021 to August 2022. Stu [...]

1397 9123

Open Access Review

Beneficial Effects of Acupuncture for Depression-A Possible Mediation of Peripheral Sensory Stimulation and Central Oxytocin Release

Received: 28 August 2023;  Published: 27 February 2024;  doi: 10.21926/obm.icm.2401016

Abstract

In modern society, depression is one of the most common mental disorders. It is generally thought that depression is due to the disorders of neuronal circuits and chemical balance in the brain. Patients with depression often receive treatment with selective serotonin reuptake inhibitors (SSRIs). However, recent studies suggest that the magnitude of benefit of pharmacological treatment is quite limited for these patients. Although recent studies propose acupuncture as a non-pharmacological approach to managing depre [...]

1119 6861

Open Access Review

Trajectories and Status of Transgender Elderly Across the World and in Spain: A Narrative Review

Received: 06 November 2023;  Published: 27 February 2024;  doi: 10.21926/obm.geriatr.2401271

Abstract

Older trans people have been largely unaddressed both in the context of the LGBTIQ+ community and in studies on geriatrics and aging. This literature review compiles up-to-date information on transgender elders, providing a summary of the Spanish historical context in which trans people have been raised, and analyzes the areas in which to center possible courses of action and research on a global scale. The themes tackled are the presence of victimization and violence; the effects of medical transition, taking into [...]

1642 11705

Open Access Original Research

Dancing Exercise Enhances Metabolic Functions via Hypercortisolism-Mediated Inhibition of Inflammatory Cytokines in Healthy Adult Volunteers

Received: 04 December 2023;  Published: 27 February 2024;  doi: 10.21926/obm.icm.2401015

Abstract

Regular physical activity has been proven to improve metabolism, slow aging, and decrease the likelihood of various health conditions such as obesity, type 2 diabetes, and cardiovascular disorders. Hence, dancing was evaluated for its effects on cardiovascular, liver enzymes, and biochemical markers among healthy adults. Forty (40) healthy adults (20-40 years old) were chosen for the study, with an average age calculated. Those with certain health conditions or habits were not allowed to participate. Twenty (20) me [...]

1355 8962

Open Access Review

MiRNAs as Promising Therapeutic Targets for Breast Cancer

Received: 27 November 2023;  Published: 26 February 2024;  doi: 10.21926/obm.genet.2401215

Abstract

Breast cancer (BC) is the most common cause of cancer-related death and is the malignancy most frequently diagnosed in females worldwide. BC incidence is predicted to continue increasing worldwide. Without interventions, annual new cases will reach over 3 million by 2030. Genetic abnormalities account for almost 70% of all BC cases worldwide. Biological pathways implicated include non-coding RNAs (ncRNAs). MiRNAs are small non-coding RNA molecules that play a role in post-transcriptional regulation of gene expressi [...]

1548 9831

Open Access Research Article

B5N10 Nanocarrier Functionalized with Al, C, Si Atoms: A Drug Delivery Method for Infectious Disease Remedy

Received: 27 November 2023;  Published: 21 February 2024;  doi: 10.21926/obm.genet.2401214

Abstract

As proof has recommended a close connection between COVID-19 and neurodegenerative disorders, this article aims to investigate the chloroquine (CLQ) drug as the SARS-CoV-2’s primary protease, which can prevent in vitro viral duplication of all diverse experiments to present. CLQ is an anti-viral drug enlarged by Pfizer, which can operate as an orally effective 3C-like protease inhibitor. In this study, CLQ has been assessed for its effectiveness against coronavirus by trapping it within a boron nitride nanoca [...]

1223 5424

Open Access Commentary

Older LGBTQ People and Religious Abuse: Implications for the UK Regulation of Care Provision in Later Life

Received: 16 October 2023;  Published: 21 February 2024;  doi: 10.21926/obm.geriatr.2401270

Abstract

Research suggests health, social care, and social work professionals who are highly religious, and adhere closely to traditional doctrine, are more likely to take a negative view of LGBTQ people. This includes those who provide services to older people. Negative attitudes towards lesbian, gay, bisexual, trans and/or queer (LGBTQ) people can translate into poor care and even abuse. This commentary discusses recent literature on older LGBTQ people’s experiences of religious abuse. It highlights the concerns among man [...]

1432 10214

Open Access Review

A Review of North American Prospects for Power and Hot-Water Generation with Thermal Energy

Received: 20 November 2023;  Published: 21 February 2024;  doi: 10.21926/jept.2401007

Abstract

This article outlines an innovative approach to explore thermal energy extraction for power generation or industrial hot water applications. Unlike traditional steady-state models, this approach embraces time-variant scenarios, explicitly incorporating a cyclical fluid circulation strategy to maintain a stable surface fluid temperature or power output. By introducing an increasing and decreasing stepwise rate sequence and an intermittent circulation strategy, the method aims to optimize efficiency in response to va [...]

1133 6171

Open Access Original Research

Nonlinear Optimal Control for a PMLSG-VSC Wave Energy Conversion Unit

Received: 16 September 2023;  Published: 21 February 2024;  doi: 10.21926/jept.2401006

Abstract

This article aims to treat the nonlinear control problem for the complex dynamics of a wave energy unit (WEC) that consists of a Permanent Magnet Linear Synchronous Generator (PMLSG) and a Voltage Source Converter (VSC). The article has developed a globally stable nonlinear optimal control method for this wave power generation unit. The new method avoids complicated state-space model transformations and minimizes the energy dispersion by the control loop. A novel nonlinear optimal control method is proposed for the [...]

1367 7280

Open Access Review

Self-Healing Concrete Techniques and Technologies and Applications

Received: 30 April 2023;  Published: 21 February 2024;  doi: 10.21926/rpm.2401006

Abstract

The main weakest point of concrete is its exposure to cracks, and concrete structure repair is expensive, especially for infrastructure maintenance, which is difficult to access. The ability of self-healing concrete (SHC) to successfully heal fractures without the assistance of humans has received much attention since it increases operational life and lowers maintenance expenses. This paper reviews various techniques and technologies of autogenous and autonomous self-healing concrete. Much more attention is given t [...]

7071 72891

Open Access Original Research

Artocarpus Communis Seed Regulates P53, IRS, HsD17β2, FTO, and CYP11a Genes in Polycystic Ovarian Syndrome Rats

Received: 20 November 2023;  Published: 20 February 2024;  doi: 10.21926/obm.genet.2401213

Abstract

Polycystic ovarian syndrome (PCOS) is a prevalent endocrine illness that affects 5-10% of reproductive women globally. It is a multifaceted hormonal disorder characterized by the involvement of numerous molecular mechanisms that contribute to its development. This study investigates the effect of Artocarpus communis seed on the hormonal imbalance and P53, IRS, HsD17β2, FTO, and CYP11a genes expression in the ovaries of letrozole-induced polycystic ovarian syndrome rats. To induce PCOS in 30 female Wistar rats, [...]

1402 5718

Open Access Review

Chronic Lung Allograft Dysfunction, a Review in 2023

Received: 25 May 2023;  Published: 20 February 2024;  doi: 10.21926/obm.transplant.2401207

Abstract

Chronic allograft dysfunction (CLAD) is one of the leading causes of death after lung transplantation [1]. CLAD is a progressive and irreversible decline in lung function after transplant, manifested as an obstructive, restrictive, or mixed ventilatory impairment without any identifiable etiology as infection or acute rejection. Multiple risk factors have been associated with this condition. Despite its significant effect on the mortality of transplanted patients, there is still a lack of powerfully effective thera [...]

1773 18783

Open Access Short Communication

Good or Great: Which One Are You?

Received: 17 December 2023;  Published: 19 February 2024;  doi: 10.21926/obm.geriatr.2401269

Abstract

Clinicians caring for patients, especially those with chronic diseases or older adults, need to recognize the value of being able to transition away from aggressive care when appropriate and focus on a more palliative approach. Research has shown that patients want to have goals of care discussions and maintain autonomy at the end of life. These goals of care discussions can be challenging, and clinicians must prioritize and develop this skill in order to provide their patients with what they may need most. Being a [...]

1146 4816

Open Access Original Research

Erectile Function in Men during the COVID-19 Pandemic

Received: 25 August 2023;  Published: 18 February 2024;  doi: 10.21926/obm.icm.2401014

Abstract

This research focused on two age groups of men (under 40 and over 40 years) and their sexual function during the COVID-19 pandemic. Somatic examinations, including the measurement of hormone levels, were conducted on all patients. The subjects also completed two questionnaires and provided personal history data. The first questionnaire covered the evaluation of erectile function, while the second assessed psychosocial trauma and stress. The results in the first group (men under 40 years of age) showed a correlation [...]

1166 5540

Open Access Case Report

Examining the Carbon Management Strategies of Diebold Nixdorf

Received: 28 July 2023;  Published: 17 February 2024;  doi: 10.21926/aeer.2401007

Abstract

Carbon management is imperative to curb global temperature increases and mitigating climate change impacts. This report explores the carbon management strategies employed by Diebold Nixdorf, a multinational financial and retail technology company. As of 2021, the company has not established specific reduction targets and has not committed to achieving net zero emissions. The company employs diverse carbon reduction strategies, such as carbon offsetting, solar energy, and fleet improvements, with notable projects li [...]

1552 8828

Open Access Review

The Role of Cognition in Balance Control

Received: 14 September 2023;  Published: 17 February 2024;  doi: 10.21926/obm.neurobiol.2401211

Abstract

Balance is the ability to move and/or preserve a particular position while not falling under external force. Human balance is a complex process of integration and coordination of the sensory, motor, and biomechanical components, which is influenced by intrinsic and exogenous factors. One inherent factor that is hypothesized to have an impact on balance is cognition. However, studies about cognition's role in balance control are still limited, and study literature is needed to gain a better understanding. Cognition [...]

2913 17219

Open Access Short Communication

Mental Health among the Elderly in Nepal: Special Emphasis on Depression

Received: 21 December 2023;  Published: 08 February 2024;  doi: 10.21926/obm.geriatr.2401268

Abstract

This paper discusses the impact of Depression on the aging population. It also tries to explore the psychosocial risk factors and burden associated with geriatric depression in low-and-middle-income (LAMI) countries. Nepal, a South Asian developing country, is resource-poor and research-naïve. Research, in general, and mental health studies, in particular, are the least prioritized in this country. The lack of culturally adapted psychiatric inventories is one of the possible reasons for the low number of mental hea [...]

1521 8937

Open Access Review

Floating Oscillating Water Column Wave Energy Converters: A Review of Developments

Received: 09 December 2023;  Published: 07 February 2024;  doi: 10.21926/jept.2401005

Abstract

The main challenge in designing offshore renewable energy structures is to ensure their structural integrity on a life cycle basis while operating in harsh environments and, in parallel, being financially competitive and environmentally friendly concerning other types of energy systems. The Oscillating Water Column (OWC) converters are among the first energy converters to be developed and deployed into the sea due to their relative simplicity of operation and relatively small number of moving parts. This review pro [...]

5828 55278

Open Access Original Research

Do Magnetic Monopoles Exist?

Received: 21 October 2023;  Published: 07 February 2024;  doi: 10.21926/rpm.2401005

Abstract

In this paper, we continue our previous work by discussing the consequences of curvature in spacetime caused by the presence of mass and the implications of this. We address the question raised by Dirac regarding the impact of a magnetic monopole on the quantum world. We discuss quantization concerning the solid angles observed, which may have a connection with a magnetic monopole.

1831 12142

Open Access Original Research

Elementary Collective Effects in Systems Containing Small Fermion-Numbers

Received: 14 October 2023;  Published: 06 February 2024;  doi: 10.21926/rpm.2401004

Abstract

Collective effects are a typical nuclear feature that refers to the behavior of a group of N fermions (protons and neutrons) within the atomic nucleus. Our interest lies in light nuclei only. Thus, we consider here, using the Lipkin model, a small-N fermion system at low-temperature T and discover -collective phenomena. Our fermion-model simplicity allows one to gain insight into collective fermion behavior. We focus attention, for N<20, on several quantifiers. These include standard ones related to thermal [...]

1373 5793

Open Access Research Article

Monitoring Energy-Loss-Driven-Cost by Using Earned Value Simulation in Complex Systems

Received: 24 July 2023;  Published: 06 February 2024;  doi: 10.21926/jept.2401004

Abstract

The economic impact of energy loss stemming from end-user electricity consumption is a significant concern, with historical trends revealing escalating costs. Effectively managing both peak and off-peak demands remains a formidable challenge due to the unpredictable nature of consumer behaviors, leading to energy wastage. This study delves into the nexus of demand uncertainty, financial repercussions, and potential strategies to mitigate energy losses in the evolving landscape of electricity consumption.that causes [...]

1254 6918

Open Access Original Research

Evaluation of Total Parenteral Nutrition in the Autologous Transplantation Setting in Patients with AML: A Retrospective Exploratory Analysis

Received: 29 July 2023;  Published: 04 February 2024;  doi: 10.21926/obm.transplant.2401206

Abstract

Malnutrition remains a clinical challenge in AML patients undergoing autologous hematopoietic stem cell transplantation (ASCT), leading to physical deconditioning and prolonged hospitalization. Prospective data are mainly lacking to identify those patients who may particularly benefit from parenteral nutrition in this setting. This observational, non-randomized, retrospective, exploratory cohort study assessed the nutritional development in patients following high-dose chemotherapy (HDCT) with ASCT and explored the [...]

1326 6740

Open Access Original Research

Efficacy and Safety of Andrographolide and Favipiravir Versus Favipiravir Monotherapy in Patients with Mild COVID-19 Infection: A Multicenter Randomized Controlled Trial

Received: 08 December 2023;  Published: 02 February 2024;  doi: 10.21926/obm.icm.2401013

Abstract

Reports indicate that Andrographolide inhibits viral replication and reduces COVID-19 symptoms. This study aimed to determine Andrographolide's additional effect and safety in mild COVID-19 patients treated with favipiravir. A multicenter, open-labeled, randomized controlled trial was conducted from October 2021 to February 2022. The patients were randomized to receive a combination of Andrographolide and favipiravir or favipiravir monotherapy. The primary outcome was the occurrence rate of severe pneumonia. The se [...]

1469 10877

Open Access Editorial

Pain and Neurobiology

Received: 01 February 2024;  Published: 02 February 2024;  doi: 10.21926/obm.neurobiol.2401210

Abstract

Neurobiology is an expansive field of studies encompassing the nervous system's anatomical and physiological aspects [1]. This complex framework's deep study and understanding have facilitated a more intricate comprehension of the interconnections among various nervous system components implicated in pain perception, transmission, modulation, and adaptation.

1289 6199

Open Access Review

Exploring the Regenerative Potential of Stem Cells for Treating Eye Diseases: A Review of the New Findings

Received: 27 September 2023;  Published: 31 January 2024;  doi: 10.21926/obm.genet.2401212

Abstract

The escalating prevalence of vision loss due to eye diseases has instigated a quest for innovative therapies, given that conventional approaches often fall short in repairing and regenerating damaged eye tissues, particularly the retina. Stem cell-based interventions have emerged as a promising avenue, with numerous studies in animal models and human trials exploring their potential to enhance visual acuity. Beyond addressing conditions like age-related macular degeneration (AMD) and diabetic retinopathy (DR), stem [...]

1332 6907

Open Access Review

Modified Organized Systems by Incorporation of Carbon Allotropes and Derivatives for Electron Shuttle, ET, FRET, MEF, and Quantum Biology Coupling

Received: 14 October 2023;  Published: 31 January 2024;  doi: 10.21926/rpm.2401003

Abstract

This communication was brief to show how high conjugated carbon-based structures and carbon allotropes could participate as electron shuttles, semiconductors, quantum emitters, and Optoelectronic processors within confined nanostructured organized systems. In particular, it was focused on nanoassemblies such as vesicles, micelles, and lipidic nanoparticles and incorporated insights from other types of nanomaterials that could afford to develop new organized systems. In these cases, the term organized system was use [...]

1130 6886

Open Access Research Article

The Indigo Project: Participatory Action Research with Gender and Sexual Minority Survivors of Elder Abuse

Received: 27 November 2023;  Published: 31 January 2024;  doi: 10.21926/obm.geriatr.2401267

Abstract

Though research suggests that older adults belonging to gender and sexual minorities (GSM) are at greater risk of abuse and neglect, more needs to be done to investigate this situation, provide solid data, offer support to survivors and better inform those providing services. This article reports on a participatory action research project in which nine older adults with lived experience of abuse were interviewed, as were the seniors’ programmer from our community partner organization and a trauma counsellor who sup [...]

1146 6975

Open Access Original Research

Knowledge and Attitudes Towards Use of Complementary and Integrative Health Therapies for Veterans with Opioid Use Disorder in the Veterans Health Administration

Received: 20 December 2023;  Published: 31 January 2024;  doi: 10.21926/obm.icm.2401012

Abstract

The Veterans Health Administration (VA) offers complementary and integrative health (CIH) therapies to Veterans with chronic pain and opioid use disorder (OUD). While CIH therapies have known benefits for chronic pain, less research exists on its use for patients with OUD. In this qualitative study, we aimed to assess provider and patient perceptions of CIH therapies for Veterans with OUD. We interviewed 45 providers involved in OUD care and 17 Veterans with OUD from five VA medical centers as part of a larger mixe [...]

1240 6085

Open Access Case Report

How do Water Companies Address Environmental Indicators in their ESG Reports?

Received: 26 July 2023;  Published: 30 January 2024;  doi: 10.21926/aeer.2401006

Abstract

As climate change is becoming an increasingly crucial issue, it has become critical for firms to report on their Environmental, Social, and Governance (ESG) aspects. In particular, this research analyzes how environmental indicators are dealt with and reported on. In the case study examined, namely the company American Water Works, GHG emissions and water management were the most important issues to the stakeholders according to the materiality assessment. It was found that the firm has significantly reduced its GH [...]

2973 11465

Open Access Original Research

LFO Damping Enhancement in Multimachine Network Using African Vulture Optimization Algorithm

Received: 20 June 2023;  Published: 30 January 2024;  doi: 10.21926/jept.2401003

Abstract

The prolonged presence of low-frequency oscillation (LFO) in power system networks (PSN) poses a significant threat to their stability. Hence, engineers and researchers have continuously developed effective strategies to mitigate the issue and enhance the stability of the PSN. This article proposes a new approach using the African Vultures Optimization Algorithm (AVOA) to design robust Power System Stabilizers (PSS) and enhance the LFO damping in multi-machine networks. The damping ratio-based objective function mi [...]

1114 5974

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