P7 - Articles - Open Access, Fast Publication, Free Publication, Timeliness, Ground-breaking research, Peer review, LIDSEN, Science Journal, Engineering Journal, Health Science Journal, Crossref Indexed, Google Scholar Indexed, Low APC, Original Research Articles

Table of Content

Open Access Original Research

Probabilistic Modeling of Cyber-Physical Microgrid Systems to Evaluate the Reliability and Resiliency Implications of Cyber Attacks

Rajesh Karki and

Binamra Adhikari

Received: 02 April 2024; Published: 07 August 2024; doi: 10.21926/jept.2403015

Abstract

The integration of cyber and physical layer of the grid has not only introduced a microscopic spectacle to observe and ensure the efficient flow of electricity but has also exposed the interdependencies of the network. These cyber-physical interdependencies are often exploited in the form of cyber-attacks that can disable a grid introducing substantial financial losses and observable social repercussions. Thus, it is important to address the impending Achilles heel by devising pragmatic approaches to comprehensibly [...]

1799 9388

Open Access Review

Oxidative Stress in Cerebral Ischemia/Reperfusion Injury

Roberto Anaya-Fernández ,

Roberto Anaya-Prado ,

Michelle M. Anaya-Fernández ,

Miguel A. Guerrero-Palomera ,

Ivan F. Garcia-Ramirez ,

Daniel Gonzalez-Martinez ,

Consuelo C. Azcona-Ramirez ,

Citlalli S. Guerrero-Palomera ,

Claudia Garcia-Perez ,

Bernardo Tenorio-Gonzalez ,

Jose E. Tenorio-Gonzalez ,

Laisha F. Vargas-Ascencio ,

Abraham I. Canseco-Villegas ,

Gustavo Servin-Romero ,

Allen R. Barragan-Arias and

Bruno Reyna-Rodriguez

Received: 02 May 2024; Published: 07 August 2024; doi: 10.21926/obm.neurobiol.2403239

Abstract

Oxidative stress in cerebral ischemia/reperfusion injury (CIRI) involves reactive oxygen and nitrogen species (ROS and RNS). Despite efficient antioxidant pathways in the brain, hypoxia triggers the production of oxygen free radicals and downregulates ATP, which leads to oxidative stress. Sources of free radicals during CIRI include Ca2+-dependent enzymes, phospholipid degradation and mitochondrial enlargement. Upon reperfusion, the abrupt increase of oxygen triggers a massive radical production via enzymes like xa [...]

1503 10952

Open Access Review

Tau-Targeted Immunotherapy for Alzheimer's Disease: Insight into Clinical Trials

Nadia El Kadmiri

Received: 16 August 2023; Published: 07 August 2024; doi: 10.21926/obm.neurobiol.2403238

Abstract

The use of immunotherapy as a therapeutic approach to Alzheimer's Disease (AD) is gaining rapid interest, with the primary goal of targeting abnormalities that impact neuronal viability through specific antibodies. Currently, clinical strategies focus intensively on targeting the two main pathologies associated with AD, beta-amyloid (Ab) and tau. This review examines ongoing research in the realm of tau immunotherapy, including clinical trials that demonstrate promising potential for halting AD progression. Several [...]

1482 16967

Open Access Original Research

COVID-19 Impact on Substance Use (Tobacco, Alcohol, Cannabis) and Stress in Medical Students

Mario Muselli ,

Loreta Tobia ,

Eleonora Cimino ,

Carlo Confalone ,

Martina Mancinelli ,

Leila Fabiani ,

Stefano Necozione and

Vincenza Cofini

Received: 30 March 2024; Published: 06 August 2024; doi: 10.21926/obm.neurobiol.2403237

Abstract

The COVID-19 pandemic has led to unprecedented challenges globally, impacting various aspects of daily life, including education. This study examines the effects of the pandemic on stress levels and substance use among Italian medical students. Two independent surveys were conducted: 388 medical students were interviewed before the epidemic, and 222 medical students a year after the COVID-19 epidemic began. Results revealed significant changes in stress levels, with a reduction in mild stress and an increase in sev [...]

940 7720

Open Access Case Report

Use of Homeopathy in Patients Suffering from Long COVID-19 (LONGCOVIHOM): A Case Series

Michael Takacs ,

Michael Frass ,

Anja Pohl-Schickinger ,

Philippa Fibert ,

Peter Lechleitner ,

Menachem Oberbaum ,

Ilse Leisser ,

Peter Panhofer ,

Kavita Chandak and

Petra Weiermayer

Received: 04 May 2024; Published: 06 August 2024; doi: 10.21926/obm.icm.2403045

Abstract

In some patients, coronavirus (COVID-19) can cause symptoms that last weeks or even months after the infection has gone. Long COVID-19 was defined as a confirmed initial COVID-19 infection, the presence of signs and symptoms more than four weeks after initial infection, and the persistence or appearance of signs and symptoms that another condition cannot explain and did not exist before infection. This study aimed to describe the effect of adjunctive individualized homeopathic treatment delivered to Long COVID-19 p [...]

1193 50265

Open Access Review

Efficacy of Motor Imagery in the Rehabilitation of Stroke Patients: A Scope Review

Danilo Donati ,

Giacomo Farì ,

Federica Giorgi ,

Riccardo Marvulli ,

Francesco Quarta ,

Andrea Bernetti and

Roberto Tedeschi

Received: 29 May 2024; Published: 06 August 2024; doi: 10.21926/obm.neurobiol.2403236

Abstract

This review examines the efficacy of motor imagery (MI) as a supplementary rehabilitation technique for stroke patients. Nine randomized controlled trials (RCTs) were analyzed, highlighting MI's potential to enhance motor recovery, mobility, balance, and psychological well-being. Significant improvements in upper-limb function were observed with combined mental and physical practice, evidenced by notable gains in Fugl-Meyer Assessment (FMA) and Action Research Arm Test (ARAT) scores. MI-based exercise programs impr [...]

1191 18411

Open Access Review

Yoga as a Potential Tool for Filling Implementation Gap in Promoting Better Mental Health in Geriatric Age Group at Global Level: A Scoping Review

Vikas Dhikav ,

Prerna Bhati ,

Pankaj Kumar and

Praveen Kumar Anand

Received: 18 June 2023; Published: 05 August 2024; doi: 10.21926/obm.geriatr.2403284

Abstract

This scoping review aims to review the effectiveness of yoga as a complementary intervention for improving mental health outcomes in the geriatric population globally. Yoga is practiced by millions worldwide. Since practitioners of yoga claim to have calmer minds and better psychological and physical health, this topic needs to be reviewed at length. There is a considerable treatment gap worldwide in treating mental disorders, especially in old age, and there is a shortage of low-cost, feasible, and acceptable prev [...]

1395 7475

Open Access Review

Machine Perfusion of Donor Hearts – The Recovery and Transplantation of Previously Unrecoverable Hearts

Sanjay Dutta ,

Jeanette E. Villanueva ,

Yashutosh Joshi ,

Ling Gao ,

Paul Jansz and

Peter S. Macdonald

Received: 02 April 2024; Published: 05 August 2024; doi: 10.21926/obm.transplant.2403222

Abstract

Heart transplantation remains the gold standard treatment for end-stage heart failure. With an increasing population and improving medical therapy there is an increasing number of patients who would benefit from heart transplantation but are unable to receive one due to a shortage of suitable donor organs. This ongoing need, and significant limitations with traditional cold static storage (CSS), have driven the development of machine perfusion technology that have expanded the donor pool. Machine perfusion is divid [...]

1238 6855

Open Access Original Research

Miscarriages after Natural Conception & IVF: Comparative Study of Genetic Analysis of Products of Conception

Elena V. Kudryavtseva ,

Sergey N. Fedenev ,

Ilia V. Kanivets ,

Anastasiya N. Troitskaya and

Vladislav V. Kovalev

Received: 30 April 2024; Published: 05 August 2024; doi: 10.21926/obm.genet.2403255

Abstract

Assisted reproductive technologies (ART), including in vitro fertilization (IVF), are modern medical technologies widely used in developed countries. A frequent complication of pregnancy resulting from ART is miscarriage. The leading cause of miscarriage, both sporadic and recurrent, is chromosomal abnormalities (CA) of the embryo. To compare the frequency and structure of chromosomal abnormalities (CA) of the embryo during miscarriages after IVF and natural conception. Retrospective cohort comparative study. The s [...]

1027 7424

Open Access Case Report

Exercise and Psychomotor Rehabilitation in a Patient with Alzheimer’s Disease: A Case Report

Catarina F. Martins ,

Jorge Soares and

Maria Paula Mota

Received: 20 March 2024; Published: 01 August 2024; doi: 10.21926/obm.neurobiol.2403235

Abstract

Alzheimer's disease is a neurodegenerative condition that impacts an individual's physical, cognitive, and social well-being, ultimately resulting in a decline in independence and functionality. This case report explores how a program combining multimodal physical exercise and psychomotor rehabilitation can improve outcomes in interventions for Alzheimer's disease patients. This approach can enhance treatment effectiveness and provide researchers and practitioners with additional therapeutic options. The participan [...]

1273 11024

Open Access Research Article

Physical Characterization of Solar Thermal Energy Storage (TES) Materials for Solar Dryers: Case of Volcanic Stone (Pozzolan) in Chad

Michel Boukar ,

Etienne Tchoffo Houdji ,

Dimitri Valdes Tchuindjang Kwatchie ,

Guy Bertrand Tchaya and

Danwe Raidandi

Received: 25 March 2024; Published: 01 August 2024; doi: 10.21926/jept.2403014

Abstract

Many sensible heat storage materials are regularly used as thermal energy storage (TES) systems to improve the efficiency of solar dryers. The present work focuses on the effects of the volume and particle sizes of a volcanic stone (pozzolan) for the same purpose. Samples soaked in matt black and without soaking were also considered. Heat charge and discharge tests were carried out by exposing the pozzolan contained in a solar collector of the direct solar dryer (DSD) and indirect solar dryer (ISD) to the sun. Char [...]

1967 8971

Open Access Original Research

Evaluation of Add-On Individualized Homeopathic Medicines Products in the Treatment of Symptomatic COVID-19 Managed at Home: A Double Blind, Placebo-Controlled, Randomized, Exploratory Clinical Trial

Renata Lemonica ,

Isabela Almeida Cunha ,

Jéssica Layane Costa Melo ,

Sandra Regina Caram ,

José Eduardo Fuser Bittar and

Karina Pavao Patricio

Received: 23 March 2024; Published: 31 July 2024; doi: 10.21926/obm.icm.2403044

Abstract

Homeopathy has shown promise in fighting epidemics, leading to potential applications in the COVID-19 clinical cases. To assess the impact of add-on individualized homeopathic medicinal products (IHMP) on improving clinical outcomes and time to medical discharge in COVID-19 patients, a prospective, double-blind, randomized, placebo-controlled, parallel-group exploratory clinical trial was conducted in a São Paulo state municipality, Brazil, between February and July 2021. 82 (unvaccinated) patients with conf [...]

1162 10164

Open Access Case Report

End-of-Life Skin Changes: Make Sure You Know What They Mean, a Case Study

Elsa Abreu ,

Catarina Simões and

Rita Figueiredo

Received: 02 March 2024; Published: 31 July 2024; doi: 10.21926/obm.geriatr.2403283

Abstract

Skin is the largest organ of the human body. Skin changes can result from natural ageing, as well as from acute or chronic diseases and failure of body systems. Various types of wounds are identified in Palliative Care, and terminal pressure ulcers are often incorrectly classified. This case study highlights the importance of recognizing skin ulcers in patients’ last hours and days of life as a diagnostic indicator for impending death. The first focus of nursing care was pain management and maintaining skin integri [...]

1096 7507

Open Access Review

Exploring Multitargets Treatment for Diabetes

Bolanle Adenike Akinsanola ,

Matthew Iyobhebhe ,

Tobiloba Christianah Maduakolam-Aniobi ,

Tomilola Debby Olaolu ,

Damilare Emmanuel Rotimi and

Oluwafemi Adeleke Ojo

Received: 17 February 2024; Published: 30 July 2024; doi: 10.21926/obm.genet.2403254

Abstract

Diabetes Mellitus (DM) is a degenerative disease that modifies the body’s glucose metabolism. Although glucose is a vital energy source for body cells, individuals with diabetes can either not use insulin efficiently or do not create enough of this hormone, which controls blood sugar. This review aimed to explore the multi-target treatment for diabetes. This study investigates explicitly recent reports published in peer-reviewed journals indexed in various databases, including Web of Science, Scopus, PubMed, Google [...]

771 5139

Open Access Original Research

COVID-19’s Psychological Threats and Future Career Anxiety among University Students

Nadia A. Abdelmegeed Abdelwahed and

Muhammad Sufyan Ramish

Received: 17 May 2024; Published: 30 July 2024; doi: 10.21926/obm.neurobiol.2403234

Abstract

The COVID-19 pandemic brought different intolerable and uncomfortable situations that ruined the students' academic performance, career opportunities, and social lives through depression, anxiety, fear, uncertainty, and mental illness. In this study, we examined the psychological threats of the COVID-19 among Egypt’s public-sector university students. We employed quantitative methods in this study and used a questionnaire to collect cross-sectional data. The Structural Equation Modeling (SEM) results show that Fear [...]

919 7677

Open Access Original Research

The Symptomatic Expression in Chinese Patients with Suspected COVID-19 Omicron Variant Infection: A Clinical Case Registry Study

Alexander Tournier ,

Yvonne Fok ,

Robbert van Haselen and

Aaron To

Received: 29 February 2024; Published: 29 July 2024; doi: 10.21926/obm.icm.2403043

Abstract

Little systematic research has been conducted into the symptomatic expression of COVID-19 infections in patients. It is known that symptomatic expression varies between patients, but the nature and extent of this variability is poorly understood. This paper elaborates on the symptoms reported by Chinese patients infected with COVID-19 during the Omicron wave, and compares this with available data from other countries. This was an observational clinical case registry study of Chinese patients with suspected Omicron [...]

886 4771

Open Access Research Article

Cultural Eutrophication Impacts on New River in Northern Belize: A Community Capitals Assessment

Kristin Drexler and

Ed Boles

Received: 02 March 2024; Published: 25 July 2024; doi: 10.21926/aeer.2403017

Abstract

Watershed health and integrity are essential to human and ecosystem health and well-being. New River watershed communities in northern Belize, Central America are vulnerable to annual ‘cultural eutrophication’ - natural eutrophication exacerbated by human activity. Human-caused pollution from agriculture, septic effluent, and industrial drainage, in combination with extended drought and the slow flow of New River, has caused more frequent and prolonged periods of eutrophication. In this qualitative study, 42 New Ri [...]

1434 13535

Open Access Original Research

Construction and Evaluation of a Modular Anthropomorphic Phantom of the Skull with an Exchangeable Specimen Jar to Optimize the Radiological Examination of Temporal Bone Pathology

Malin Vestin Fredriksson ,

Love Kull ,

Anton Rönnblom ,

Lennart Flygare ,

Diana Berggren and

Krister Tano

Received: 26 March 2024; Published: 25 July 2024; doi: 10.21926/rpm.2403018

Abstract

To develop a modular anthropomorphic phantom to evaluate the performance of radiological techniques for detecting pathologies in the temporal bone region. A phantom was constructed using a human skull, temporal bone specimen, and 3D-printed contour of a human skull. The human skull was embedded in tissue-equivalent plastic, with a cavity to hold the plastic jars containing the exchangeable freshly frozen human temporal bones. Subsequently, stepwise introduction and examination of different clinicopathological scena [...]

1163 5573

Open Access Review

BK Virus-Associated Nephropathy in Adult Patients Post Kidney Transplantation: What Progress in 30 Years of History?

Yassamine Bentata

Received: 24 January 2024; Published: 25 July 2024; doi: 10.21926/obm.transplant.2403221

Abstract

Completely unknown before the 90s and exceptional up to the 2000s, BK virus nephropathy (BKvN), usually known as polyomavirus-associated nephropathy, has emerged as a significant and severe viral complication in kidney transplantation (KT). More than twenty years after Gardner's discovery of BKv in 1971, Purighalla described, in 1995, the first case of BKvN. Four years later in 1999, Nickeleit et al. published a first series of five cases of BKvN and made very precious and pertinent contributions to understanding t [...]

1096 14078

Open Access Research Article

Filial Piety Discrepancy and Wellbeing among Older Chinese Immigrants Living in Canada: The Role of Acculturation and Living Arrangement

Vivian Huang and

Alexandra J. Fiocco

Received: 02 April 2024; Published: 23 July 2024; doi: 10.21926/obm.icm.2403042

Abstract

This survey-based, cross-sectional study explored the independent and synergistic effect of filial piety discrepancy (FPD), acculturation, and living arrangement on the psychological, social, and physical wellbeing of older Chinese immigrants living in Canada. A total of 299 older Chinese immigrants were recruited from community organizations in the Greater Toronto Area. Participants completed questionnaires that assessed demographic information, filial piety, living arrangement, acculturation, and three domains of [...]

1379 7390

Open Access Original Research

Leaf Mediated Curcuma sp. Silver Nanoparticles as Catalyst - Evaluating Their Antioxidant, Cytotoxicity, Para-Nitrophenol Catalytic and Photocatalytic Activity

Mathivathani Kandiah ,

Dharsha Bhaskaran and

Ominda Perera

Received: 29 April 2024; Published: 22 July 2024; doi: 10.21926/cr.2403010

Abstract

Nanotechnology is a fast-rising market in catalytic research; however, the production of eco-friendly nanoparticles remains a significant challenge. In this study, silver nanoparticles (AgNPs) were synthesized from the agro-industrial waste of leaves of C. longa, C. aromatica, C. caesia, C. zedoaria, and C. amada at RT after 24 h, which was confirmed with UV-spectrophotometric evaluation between 320-520 nm. SEM revealed cubic and 30-50 nm AgNPs, while band-gap energy was presented as semi-conductors. Synthesized Ag [...]

1973 20431

Open Access Review

Impact of Pernicious Chemicals on Geopolymer and Alkali-Activated Composites Incorporated with Different Fiber Types: A Review

Khatib Zada Farhan ,

Ayman Sabry Shihata and

Adams Balade Abubakar

Received: 27 March 2024; Published: 22 July 2024; doi: 10.21926/rpm.2403017

Abstract

Over the past decade, developing geopolymer mixes to replace ordinary Portland Cement (OPC) composites has yielded positive results, leading to extensive research. The incorporation of fibers in geopolymers, besides impacting the mechanical properties, has also significantly impacted durability, mainly when dealing with the most pernicious forms of deterioration resulting from chloride attack, water penetration, sulfate attack, acid attack, as well as freeze-thaw, which occurred through chemical transgression. This [...]

1378 13143

Open Access Original Research

Investigating the Relationship between Lipid Profiles of Stroke Patients at the Time of Admission and Their Outcome

Mohadeseh Rajabpour ,

Alireza Ala ,

Eliyar Sadeghi-Hokmabadi ,

Hasan Amiri ,

Sara Rostamnezhad and

Samad Shams Vahdati

Received: 07 March 2024; Published: 19 July 2024; doi: 10.21926/obm.neurobiol.2403233

Abstract

Hyperlipidemia is one of the critical risk factors for cerebrovascular disease. Many studies have emphasized that controlling the lipid level can decrease the risk of cardiovascular and cerebrovascular events. In this article, we studied all types of lipids in stroke patients and wanted to consider any relation between lipid level in admission and outcome. This retrospective, cross-sectional study was conducted at Imam Reza Research and Training Hospital. It was performed on a sample of 2165 patients who visited th [...]

802 5266

Open Access Review

Blinatumomab vs Chemotherapy for Pediatric and Adult Acute Lymphoblastic Leukemia

Arbnora Batalli-Kepuska ,

Lidvana Spahiu ,

Emir Behluli and

Gazmend Temaj

Received: 08 February 2024; Published: 19 July 2024; doi: 10.21926/obm.genet.2403253

Abstract

Several therapeutic methods are used to cure acute lymphoblastic leukemia (ALL). Relapsed/refractory B-cell ALL (R/R B-ALL) remains the primary cause of death worldwide due to the limitation of cure. Blinatumomab is a bispecific T-cell engaging antibody used to treat R/R B-ALL. The use of blinatumomab for treating R/R B-ALL has shown to be very efficient, especially as a bridge tool to hematopoietic stem cell transplantation (HSCT). The response to blinatumomab treatment ranged from 69% after two cycles in phase II [...]

1124 6654

Open Access Research Article

Kinetic Model for the Hydrolysis of Olive Oil by Lipase in Absence of Emulsifier

Mª Carmen Márquez

Received: 27 March 2024; Published: 18 July 2024; doi: 10.21926/cr.2403009

Abstract

Lipase-catalyzed hydrolysis of olive oil has been studied in the absence of emulsifier. A simple mathematical model to predict the hydrolysis rate is derived from a proposed kinetic mechanism of the reaction. The hydrolytic reaction obeys Michaelis-Menten kinetics with a simultaneous second-order enzyme deactivation. The model predictions closely agree with the experimental results.

1868 10406

Open Access Review

Nutritional Profile and Topic Management for Wound Healing in Children with Epidermolysis Bullosa: What Is the Evidence? A Systematic Review

Maria Lúcia dos Santos ,

Ana Cristina Monteiro ,

Andréa Nascimento ,

Sívia Barbosa ,

Artur Delgado and

Patrícia Zamberlan

Received: 11 April 2024; Published: 17 July 2024; doi: 10.21926/rpn.2403010

Abstract

Epidermolysis Bullosa (EB) is a rare genetic disorder characterized by fragile skin that blisters and tears easily, leading to significant morbidity and mortality. Depending on the specific genetic mutations and the proteins involved, EB can be classified into several subtypes whose molecular complexity is compounded by the variability in mutation types (missense, nonsense, insertions, deletions), their locations within the genes, and the resultant effects on protein function. This systematic review aimed to identi [...]

2057 9014

Open Access Original Research

Elaboration, Structural and Optical Characterization of the New Ternary Chalcogenide SnSb₂S₅

Assohoun Fulgence Kraidy ,

Islam M. El Radaf ,

Andreas Zeinert ,

Abdelilah Lahmar ,

Aime Pelaiz-Barranco ,

Pardis Simon and

Yaovi Gagou

Received: 29 March 2024; Published: 17 July 2024; doi: 10.21926/jept.2403013

Abstract

In this study, tin antimony sulfide (SnSb2S5) thin films with 200 nm, 312 nm, and 431 nm thicknesses were successfully fabricated using thermal evaporation. These films' structural, optical, and photoanode properties were meticulously characterized to assess their suitability for photovoltaic applications. X-ray diffraction (XRD) analysis confirmed the presence of an orthorhombic symmetry phase within the Pnma space group, ensuring the crystalline quality of the films. Raman spectroscopy further validated the cryst [...]

1017 5767

Open Access Review

Practices Used in Health and Social Services for the Management of Mistreatment Situations towards Adults in a Context of Gender and Sexual Diversity: A Scoping Review

Mélanie Couture ,

Julien Gauthier-Mongeon ,

Pearce Simamonika ,

Rosalie Bernard ,

Kevin St-Martin ,

Rosalie Lacasse and

Sarita Israel

Received: 18 December 2023; Published: 17 July 2024; doi: 10.21926/obm.geriatr.2403282

Abstract

Research indicates that adults in the context of gender and sexual diversity (GSD) experienced more violence and discrimination than the rest of the population. GSD refers to all the diversities of sexual characteristics, sexual orientations and gender identity of a person or a group. To encourage the use of evidence-based interventions in health and social services, it is important to extrapolate from the scientific literature how mistreatment situations are managed in this context. A scoping review was conducted [...]

1380 7381

Open Access Review

Potential Use of Human Mesenchymal Stem Cells (hMSCs) in Pancreatic Damage/Cancer

Havva Özgen Eyüpoğlu ,

Erol Eyüpoğlu and

Nedime Serakinci

Received: 13 March 2024; Published: 17 July 2024; doi: 10.21926/obm.genet.2403252

Abstract

Pancreatic damage and pancreatic cancer pose significant challenges due to their complex pathogenesis, limited treatment options, and poor prognosis. In recent years, the potential use of human Mesenchymal Stem Cells (hMSCs) has been explored to address these complex pancreatic conditions and develop novel therapeutics. hMSCs, known for their regenerative and immunomodulatory properties, offer a novel therapeutic avenue for repairing damaged tissues and possibly inhibiting cancer progression. This communication dis [...]

1092 7053

Open Access Review

The Biomolecular Basis of Gut Microbiome on Neurological Diseases

Roberto Anaya-Prado ,

Ana P. Cárdenas-Fregoso ,

Ana M. Reyes-Perez ,

Danielle M. Ortiz-Hernandez ,

Montserrat Quijano-Ortiz ,

Monica V. Delgado-Martinez ,

Ana S. Pelayo-Romo ,

Roberto Anaya-Fernández ,

Michelle M. Anaya-Fernández ,

Consuelo C. Azcona-Ramirez ,

Ivan F. Garcia-Ramirez ,

Miguel A. Guerrero-Palomera ,

Daniel Gonzalez-Martinez ,

Citlalli S. Guerrero-Palomera ,

Karina Paredes-Paredes and

Claudia Garcia-Perez

Received: 23 February 2024; Published: 16 July 2024; doi: 10.21926/obm.neurobiol.2403232

Abstract

The human gastrointestinal (GI) tract harbors many microorganisms, including viruses, protozoa, archaea, fungi, and bacteria. Altogether, these microbes constitute what we know as the gut microbiome (GM). These commensal communities have important implications for human health. They influence physiological processes through different mechanisms, including synthesizing neurotransmitters, regulating enzymatic pathways, and releasing molecules responsible for different signal pathways. The interaction between GM and b [...]

985 8147

Open Access Case Report

Implementation of Cognitive Behavioral Therapy in a Child with Obsessive - Compulsive Disorder: A Case Study

Ioannis Syros and

Xenia Anastassiou-Hadjicharalambous

Received: 19 October 2023; Published: 15 July 2024; doi: 10.21926/obm.neurobiol.2403231

Abstract

Obsessive-Compulsive Disorder (OCD) is a prevalent child and adolescent psychiatric condition characterized by substantial functional impairments. Cognitive Behavioral Therapy (CBT) has emerged as the primary therapeutic approach for managing mild to moderate cases of OCD in children and adolescents. Significant advancements have been made in applying CBT specifically to this age group in the past decade. Exposure and response prevention (ERP) is a core therapeutic technique grounded in the principle that anxiety t [...]

1323 10197

Open Access Concept Paper

Applied Pragmatic Functional Contextualism: A New Epistemological and Theoretical Framework for Applied Mental Health Research

Eli Cwinn and

Kayla Hamel

Received: 22 January 2024; Published: 10 July 2024; doi: 10.21926/obm.icm.2403041

Abstract

This paper argues that psychology, as a discipline, requires research to be situated in the context of a content-based theory. We identify several problems and pitfalls with requiring a content-based theory for applied mental health research, a priori. Nonetheless, we also articulate a rationale for why theory matters and that a new sort of theoretical framework is required for applied mental health research. We address this need by articulating a new theoretical framework called Applied Pragmatic Functional Contex [...]

905 5015

Open Access Original Research

Eryngium carlinae Extract and Exercise Improve Blood Lipid Profile and Skeletal Muscle Function in Obese Rats

Koré Monsterrat Moreno-Calderón ,

Alfredo Saavedra-Molina ,

Mariana Gómez-Barroso ,

Donovan Javier Peña-Montes ,

Christian Cortés-Rojo ,

Alain R. Rodríguez-Orozco ,

Omar Ortiz-Ayala and

Rocío Montoya-Pérez

Received: 08 January 2024; Published: 10 July 2024; doi: 10.21926/obm.icm.2403040

Abstract

An excess of adipose tissue characterizes obesity; it is associated with complications such as diabetes and cardiovascular diseases due to an alteration in the lipid profile; this condition affects all tissues; even skeletal muscle is the most affected, causing its malfunction and bringing more significant consequences. Exercise has been described as one of the best treatments to combat obesity. At the same time, E. carlinae is a plant proven to have lipid-lowering and hypoglycemic effects, improving the function o [...]

984 4499

Open Access Editorial

The Intersection of Nutrigenetics, Nutrigenomics, and the Microbiome in Human Health

Giuseppe Merra

Received: 03 July 2024; Published: 10 July 2024; doi: 10.21926/obm.genet.2403251

1374 6542

Open Access Short Review

A Narrative Review on the Use of Eye-Tracking in Rett Syndrome: Implications for Diagnosis and Treatment

Anna Passaro ,

Antonio Zullo ,

Mariacarla Di Gioia ,

Enza Curcio and

Fabrizio Stasolla

Received: 27 January 2024; Published: 05 July 2024; doi: 10.21926/obm.genet.2403250

Abstract

Rett syndrome (RTT) is a rare neurodevelopmental disorder primarily affecting females, characterized by a spectrum of debilitating symptoms that impact neurological, cognitive, and motor functions. Eye-tracking technology (ETT) has emerged as a prominent tool in Augmentative and Alternative Communication (AAC) systems, particularly for neurological patients with motor and verbal impairments. This narrative review aimed to evaluate studies conducted on the use of ETT to improve cognitive abilities in girls with RTT [...]

1252 9248

Open Access Review

Scoping Review of Nutraceuticals Use in Mediterranean Diet

María del Valle del Olmo de Dios ,

Alfonso Roberto Barros-Loscertales and

Laura Laguna Cruañes

Received: 25 September 2023; Published: 05 July 2024; doi: 10.21926/obm.icm.2403039

Abstract

Mediterranean diet, considered key to varied diets, raises whether it is necessary to supplement it with compounds like nutraceuticals to obtain more benefits. A scoping review was conducted. Nine articles were selected that compared the effects of nutraceuticals on biochemical markers (such as total cholesterol (TC), low-density lipoprotein cholesterol (LDLc)), weight, and blood pressure in various studies to the results observed in groups only exposed to the Mediterranean diet. The aim was to assess the impact of [...]

928 4864

Open Access Review

Causes of Chromosome Breakage and Mis-segregation Affecting Pregnancy and Newborn Health: An Insight into Developing Reproductive Health Preventive Strategies

Oyovwi Mega Obukohwo ,

Peggy Ejiro Ohwin ,

Rotu Arientare Rume ,

Olowe Gideon Temitope ,

Oyelere Abosede Oreoluwa and

Adelowo Joy Motunrayo

Received: 19 February 2024; Published: 05 July 2024; doi: 10.21926/obm.genet.2403249

Abstract

Chromosome abnormalities are a leading cause of pregnancy loss, developmental delays, and birth defects. These abnormalities arise from errors in chromosome structure (breakage) or number (missegregation) during cell division. Understanding the causes of these errors is crucial for developing effective preventive strategies to improve reproductive health. This paper aims to review the known causes of chromosome breakage and mis-segregation, emphasizing their impact on pregnancy and newborn health. It further explor [...]

1526 10995

Open Access Original Research

Glasgow Coma Scale Scores and Impact of Delirium on Intubated Seizure Patients Treated with Phenytoin and Lacosamide: Retrospective Analysis and Literature Review

Sara Alattar ,

Muhammad Nouman ,

Chidozie Onyiuke ,

Conrad Stasieluk and

Edwin Meresh

Received: 29 November 2023; Published: 05 July 2024; doi: 10.21926/obm.neurobiol.2403230

Abstract

Studies have shown that decrease in time intubated is associated with better prognosis. Delirium is associated with increased duration of mechanical ventilation and Intensive Care Unit (ICU) length of stay. However, there is limited report on delirium in intubated seizure patients. As per report, low Glasgow Coma Scale (GCS) increased the risk of delirium and thus increasing ICU length of stay. Information on delirium and outcome in intubated seizure patients receiving lacosamide versus phenytoin is limited. Our re [...]

1311 10800

Open Access Review

Hormonal and Physiological Manipulation Methods to Induce Polycystic Ovary in Rodents: A Review of the New Findings

Leila Naseri ,

Mohsen Akbaribazm and

Mozafar Khazaei

Received: 06 February 2024; Published: 04 July 2024; doi: 10.21926/obm.genet.2403248

Abstract

Polycystic ovary syndrome (PCOS) is the most common endocrinopathy causing non-ovulation infertility in women. Women with PCOS have higher levels of luteinizing hormone (LH), testosterone, cholesterol and triglycerides but, in contrast, lower levels of follicular stimulating hormone (FSH) and sex hormone-binding globulin (SHBG) compared with healthy counterparts. Because of the limitations of human studies, animal models of PCOS have been developed to identify appropriate therapeutics and to explore their mechanism [...]

1391 10426

Open Access Original Research

Effective Photogeneration of Singlet Oxygen and High Photocatalytic and Antibacterial Activities of Porous Mn-Doped ZnO-ZrO₂ Nanocomposites

Sergey Evstropiev ,

Andrey Shelemanov ,

Igor Bagrov ,

Anna Karavaeva ,

Kseniya Portnova and

Nikolay Nikonorov

Received: 06 April 2024; Published: 03 July 2024; doi: 10.21926/cr.2403008

Abstract

Disperse porous Mn-doped ZnO-ZrO2 nanocomposites were prepared using the facile polymer-salt method. The effect of Mn content on the crystal structure, composite morphologies, their ability to photogenate the singlet oxygen, luminescence properties, and bactericidal activities were studied. The crystal structure and morphology of these materials were investigated using XRD and SEM analysis. It was found that obtained nanocomposites consist of small (~9 nm) hexagonal ZnO and fine ZrO2 crystals and the embedding of M [...]

1302 7674

Open Access Research Article

Impact of Intravenous Immunoglobulin Replacement Therapy on Hypogammaglobulinemia and Infection in Lung Transplant Recipients

Van Anh Vu ,

Joelle Nelson ,

Helen Sweiss ,

Reed Hall ,

Holly Keyt and

Elisabeth Kincaide

Received: 29 January 2024; Published: 03 July 2024; doi: 10.21926/obm.transplant.2403220

Abstract

Secondary hypogammaglobulinemia (HGG) from immunosuppression therapy in lung transplant recipients has been associated with increased mortality, morbidity and higher risk of infection. Intravenous immunoglobulin (IVIG) for the treatment of HGG post-lung transplant is not well studied with conflicting evidence regarding efficacy. This single-center, retrospective cohort study analyzed adult lung transplant recipients with HGG receiving ≥1 dose of IVIG 0.3-0.5 g/kg. Resolution of HGG (IgG > 600 mg/dL wi [...]

913 7088

Open Access Original Research

Alpha/Theta Neurofeedback Rehabilitation for Improving Attention and Working Memory in Female Students with Learning Disabilities

Roghieh Nooripour ,

Maryam Ghanbari Viki ,

Nikzad Ghanbari ,

Fardin Farmani and

Farinaz Emadi

Received: 07 April 2024; Published: 01 July 2024; doi: 10.21926/obm.neurobiol.2403229

Abstract

Learning disabilities (LDs) encompass a range of cognitive challenges that can significantly influence students' educational experiences and overall academic performance. This study aimed to investigate the effects of alpha/theta neurofeedback rehabilitation on attention and working memory in female students with learning disabilities. This study employed a quasi-experimental design with pre-tests, post-tests, and a two-month follow-up and included a control group. Convenience sampling was used to select 40 fem [...]

2408 23608

Open Access Short Report

Integrating Palliative Medicine into Medical Education: Creating a More Compassionate Generation of Physicians

Regina M. Mackey ,

Macaila Eick ,

Sara Jacobsen ,

Abraham Labrada Satiago and

Maria I. Lapid

Received: 26 February 2024; Published: 01 July 2024; doi: 10.21926/obm.geriatr.2403281

Abstract

How should Palliative Medicine competencies be taught to medical students? In the United States and other countries, there is a consensus that teaching Palliative Medicine competencies to medical students is essential. Health agencies have also identified teaching Palliative Medicine competencies as crucial. According to Sanchez-Reilly and Ross, medical students reported that they feel better prepared to care for the elderly, patients with severe illness, and dying patients after completing formal training. The aut [...]

983 5097

Open Access Original Research

Determination of Reflectance Spectra and Colorimetry of Titanium and Tungsten Oxides Obtained by Microwave-assisted Hydrothermal Synthesis

Luana Góes Soares ,

Sandra Kunst ,

Cláudia Trindade Oliveira and

Annelise Kopp Alves

Received: 04 February 2024; Published: 01 July 2024; doi: 10.21926/cr.2403007

Abstract

Sustainability has driven the use of heterogeneous photocatalysis as one of the primary methods for environmental decontamination, reduction, degradation, remediation, or transformation of polluting chemical residues and purification treatment of effluents and wastewater. TiO2 is the most commonly used semiconductor in heterogeneous photocatalysis. It acquires relevance, as it has favorable properties, such as non-toxicity, stability in a wide range of pH, economic viability, etc., which encourage its application a [...]

1449 6655

Open Access Research Article

Spark Plasma Sintering of Cu-Ti-Ni Ternary Alloy: Microstructural, Thermal and Electrical Properties

Amos O. Oyatogun ,

Emmanuel Ajenifuja ,

Abimbola P. Popoola ,

Olawale Popoola ,

Fatai O. Aramide and

Grace M. Oyatogun

Received: 28 December 2023; Published: 01 July 2024; doi: 10.21926/rpm.2403016

Abstract

High strength and good conductivity are both critical parameters for copper-based alloys for electrical and other technological applications. This study is aimed to produce copper alloys and metal matrix composites (MMCs) with enhanced physical properties. Cu-Ti-Ni ternary alloys and MMCs samples were sintered at 600 to 700°C using spark plasma sintering (SPS), with a heating rate of 100°C/minutes, uniaxial pressure of 50 MPa, and a holding time of 10 minutes. Scanning electron microscopy (FE-SEM) was used to exami [...]

1260 6745

Open Access Review

The Importance of Responsible Electronic Waste Treatment for Sustainability

Sami Goren

Received: 02 January 2024; Published: 01 July 2024; doi: 10.21926/aeer.2403016

Abstract

Waste production is experiencing a significant increase in correlation with the growth of the human population and industrial activities. The kind of waste that is expanding at a rapid rate is known as "e-waste," which stands for electronic waste. In the context of electronic waste, the term refers to the waste produced during the disposal of electronic devices and any other components utilized in making or operating these devices. In the same way that different types of waste occur, electronic waste pollutes the e [...]

1072 6432

Open Access Review

The Interplay of Nutrition, Exercise, and Dietary Intervention for Enhanced Performance of Athletes and General Well-Being of Non-Athletes: A Review

Oghenerume Lucky Emakpor ,

Great Iruoghene Edo ,

Emad Yousif ,

Princess Oghenekeno Samuel ,

Agatha Ngukuran Jikah ,

Khalid Zainulabdeen ,

Athraa Abdulameer Mohammed ,

Winifred Ndudi ,

Susan Chinedu Nwachukwu ,

Ufuoma Ugbune ,

Joy Johnson Agbo ,

Irene Ebosereme Ainyanbhor ,

Huzaifa Umar ,

Helen Avuokerie Ekokotu ,

Ephraim Evi Alex Oghroro ,

Patrick Othuke Akpoghelie ,

Joseph Oghenewogaga Owheruo ,

Lauretta Dohwodakpo Ekpekpo ,

Priscillia Nkem Onyibe ,

Ufuoma Augustina Igbukuc ,

Endurance Fegor Isojec and

Arthur Efeoghene Athan Essaghahk

Received: 28 December 2023; Published: 28 June 2024; doi: 10.21926/obm.icm.2402038

Abstract

The optimal enhancement of athletic performance, recovery from exhaustion after exercise, and injury prevention are products of appropriate nutrition. Nutritional supplements that contain proteins, carbohydrates, vitamins, and minerals are frequently utilized in various sports to complement the recommended daily amounts. Several of these supplements have been identified to have physiological effects and, thus, are known to help enhance athletic performance and prevent injuries. Our review intends to show the interp [...]

1858 12151

Open Access Original Research

North Central Farm and Ranch Stress Assistance Center: 2020-2023: Outcomes, Lessons Learned, and Recommendations for the Future

Josie M Rudolphi ,

Courtney Cuthbertson ,

Kimberly Keller and

Rebecca Mott

Received: 26 April 2024; Published: 28 June 2024; doi: 10.21926/obm.icm.2402037

Abstract

Agricultural producers (i.e., farmers, ranchers) and agricultural workers (i.e., hired labor, farmworkers) have worse mental health than the general population and often lack access to mental healthcare. In response, the United States Department of Agriculture’s National Institute of Food and Agriculture funded four regional Farm and Ranch Stress Assistance Networks in 2019. In the north central region, the North Central Farm and Ranch Stress Assistance Center (NCFRSAC) was created in 2020 to develop, deliver [...]

1202 6806

Open Access Original Research

A Technology-Aided Program to Help People with Profound Intellectual and Multiple Disabilities Access Preferred Stimulation and Exercise Motor Responses and Visual Orientation

Giulio E. Lancioni ,

Gloria Alberti ,

Chiara Filippini ,

Nirbhay N. Singh ,

Mark F. O'Reilly and

Jeff Sigafoos

Received: 14 March 2024; Published: 28 June 2024; doi: 10.21926/obm.neurobiol.2402228

Abstract

People with profound intellectual and multiple disabilities (PIMD) are generally isolated, with a high risk of reduced stimulation input and physical inactivity. One of the strategies available to mitigate this situation relies on using technology-aided programs delivering stimulation contingent on people’s basic responses/activation. The two studies reported here were intended to extend the evidence available in this area. Specifically, Study I assessed whether a technology-aided program, which enabled participant [...]

1102 5735

Open Access Perspective

Organisational and Emotional Psychology Views on Yozan Uesugi’s Leadership

Yasuhiro Kotera ,

Jenai Lieu ,

Hou Tin Gillian Liu ,

Christian Veasey and

Kristian Barnes

Received: 09 January 2024; Published: 27 June 2024; doi: 10.21926/obm.icm.2402036

Abstract

Yozan Uesugi was a Daimyo (feudal lord) who governed an area called Yonezawa in Yamagata Prefecture, Japan from 1767 to 1823. Yonezawa was originally an impoverished provincial government which under his leadership regained a healthy financial status. His leadership style was unique among Daimyos, yet respected and regarded as an ideal by many including President John F. Kennedy. One of the characteristics of Yozan’s leadership was he demonstrated what he expected his people to do, instead of just telling them what [...]

1267 9045

Open Access Review

Review on Some Important Research Progresses in Biodegradable Plastics/Polymers

Zhong Hu and

Ruanbao Zhou

Received: 15 March 2024; Published: 27 June 2024; doi: 10.21926/rpm.2402015

Abstract

Biodegradable plastics/polymers may serve as a promising solution to the global problem of plastic waste accumulation in oceans and soil and may significantly reduce carbon emissions from the manufacturing process, since the materials used to make biodegradable polymers are carbon-based and emitted during the synthesis processes. This article systematically reviewed the existing and closely related scientific literature on materials, biomaterials, and biodegradable materials to find answers on how to effectively st [...]

2558 28508

Open Access Research Article

Development of the Stochastic Interpretation of Quantum Mechanics by E. Nelson. Derivation of the Schrödinger-Euler-Poisson Equations

Mikhail Batanov-Gaukhman

Received: 10 November 2023; Published: 26 June 2024; doi: 10.21926/rpm.2402014

Abstract

The article aims to develop the stochastic interpretation of quantum mechanics by E. Nelson based on balancing the intra-systemic contradiction (i.e., antisymmetry) between “order” and “chaos”. For the set task, it is proposed to combine two mutually opposite system-forming principles: “the principle of least action” and “the principle of maximum entropy” into one, the “principle of averaged efficiency extremum”. In a detailed consideration of the averaged states of a chaotically wandering particle, the time-indepe [...]

1088 16398

Open Access Original Research

Is Wheelchair Basketball a Symmetric or Asymmetric Sport?

Giacomo Farì ,

Enrica Chiaia Noya ,

Laura Dell'Anna ,

Vincenzo Ricci ,

Francesco Quarta ,

Laura Masiero ,

Andrea Bernetti ,

Marisa Megna and

Maurizio Ranieri

Received: 16 January 2024; Published: 25 June 2024; doi: 10.21926/obm.neurobiol.2402227

Abstract

Wheelchair basketball (WB) is a health and inclusion opportunity for people with disabilities. In the scientific literature, no evidence defines WB as a symmetrical or asymmetrical sport; however, it would be helpful to deepen this aspect because it could improve the quality of training programs and consequently speed up WB performance. In WB, the biomechanical role of the shoulders is crucial. Therefore, the symmetry index and the activation of the bilateral supraspinatus and biceps brachii muscles were investigat [...]

1330 8439

Open Access Case Report

Chromosome 7 Isodisomy in a Child with Silver-Russell Syndrome

Luis A. Méndez-Rosado ,

Alicia Vaglio ,

Roberto Lardoeyt-Ferrer ,

Albertino Candimba-Sebastiao ,

Judith Pupo-Balboa ,

Ivan Y. Iourov and

Alejandro Esperon

Received: 19 March 2024; Published: 24 June 2024; doi: 10.21926/obm.genet.2402247

Abstract

Silver-Rusell syndrome is a rare genetic disease. There is evidence that the genetic causes of the disorder are heterogeneous, with predominant alterations in the imprinted regions of chromosomes 11 and 7, in addition to other genomic alterations, such as chromosomal structural aberrations, single nucleotide polymorphisms, copy number variations, and small insertions and deletions. The most prevalent clinical manifestations include prenatal and postnatal growth retardation, dysmorphic features, and feeding difficul [...]

1022 6480

Open Access Original Research

Detection of Activated Pepsin in Bronchoalveolar Lavage and Acute Cellular Rejection in Lung Transplant Recipients

Andrés R. Latorre-Rodríguez ,

Devika Sindu ,

Sumeet K. Mittal and

Ashwini Arjuna

Received: 23 February 2024; Published: 21 June 2024; doi: 10.21926/obm.transplant.2402219

Abstract

Activated pepsin (pepA) in bronchoalveolar lavage (BAL) fluid may be a biomarker of gastric aspiration. We sought to i) evaluate the association of pepA in BAL fluid with acute cellular rejection (ACR) in a cohort of lung transplant recipients (LTRs), ii) assess the association between pepA and isolation of typical gastrointestinal microorganisms from BAL fluid, and iii) explore the accuracy of using pepA concentration as a biomarker of ACR. After IRB approval, we conducted a retrospective observational study analy [...]

1248 6300

Open Access Case Report

Art of Telesupport of Caregiver during Myasthenia Gravis Crisis by COVID-19 Infection-Related Followed by Rescue in Late-Onset Patient

Corrado Angelini

Received: 06 February 2024; Published: 21 June 2024; doi: 10.21926/obm.icm.2402035

Abstract

An 83-year-old man with myasthenia gravis was hospitalized in the ICU; support for caregivers of elderly myasthenic patients in the ICU can be a crucial aspect of their care. Myasthenia gravis is a chronic autoimmune neuromuscular disease that can cause varying levels of muscle weakness, which can significantly impact the patient's day-to-day activities and overall quality of life. This intervention was followed for over one month with success. The critical phases are presented and analyzed as a medical support art [...]

911 3739

Open Access Review

Investigating the Genetic Basis of Unexplained Infertility and Potential Chromosomal Abnormalities

Oyovwi Mega Obukohwo ,

Oyelere Abosede Oreoluwa ,

Odewale O. Comfort and

Afolabi Opeyemi Olanike

Received: 24 March 2024; Published: 20 June 2024; doi: 10.21926/obm.genet.2402246

Abstract

Infertility affects millions globally, with 10-15% of couples experiencing unexplained cases. Despite advancements in medicine, the cause remains unknown, causing emotional distress. Recent research suggests a genetic basis for this issue. This review aims to provide a better understanding of the underlying genetic factors contributing to unexplained infertility and potentially identify genetic markers that could aid in the diagnosis and treatment of this condition. A literature review was conducted to understand t [...]

2284 15598

Open Access Original Research

Physico-Chemical Study of the Anti-Diabetic Drug of [BzN-EJJ-amide] for Treatment Type2 Diabetes Using CNT Sensor by Drug Delivery Method

Fatemeh Mollaamin ,

Majid Monajjemi and

Ahmad R. Alsayed

Received: 22 February 2024; Published: 19 June 2024; doi: 10.21926/obm.genet.2402245

Abstract

The potential and selective inhibitors of protein tyrosine phosphatase 1B (PTP1B) are therapeutically useful in treating type 2 diabetes. N-Benzoyl-L-glutamyl-[4-phosphono(difluoromethyl)]-L-phenylalanine-[4-phosphono(difluoro-methyl)]-L-phenylalanineamide (BzN-EJJ-amide) (BGD) which is the ligand of 1LQF protein code extracted from protein data bank (PDB) is an inhibitor of PTP-1B that indicates selectivity over several protein tyrosine phosphatases. In this research, the interaction between the anti-diabetic drug [...]

1224 5224

Open Access Original Research

The Effect of Rake Angle and Cutting Edge Radius on the Orthogonal Cutting Process of Ti6Al4V Alloy

Mohammed Mustafa ,

Salman Pervaiz and

Ibrahim Deiab

Received: 23 February 2024; Published: 18 June 2024; doi: 10.21926/rpm.2402013

Abstract

This paper investigates the effect of rake angle, α, cutting edge radius, r, and feed rate, f, on the cutting force and cutting zone temperature during orthogonal dry cutting of Ti6Al4V. A numerical model representative of the 2D orthogonal cutting process is developed using ABAQUS/Explicit software. Johnson-Cook, (JC) constitutive material model is used to describe material plasticity. JC damage model and energy-based fracture criterion are used to describe damage initiation and evolution. Using Minitab-19 softwar [...]

1660 8645

Open Access Original Research

Establishment of an In Vitro Propagation, Transformation, and Gene Editing System in Tomato (Solanum lycopersicum)

Galal Khamis ,

Jun Chi and

Qingshun Zhao

Received: 12 January 2024; Published: 18 June 2024; doi: 10.21926/obm.genet.2402244

Abstract

Tomato (Solanum lycopersicum), a family of Solanaceae, is an annual crop grown in fields and greenhouses. Tomato is the fourth-largest agricultural crop in the world, with a market value of more than $50 billion. Numerous attempts were conducted on the tomato for further improvement via in vitro regeneration and transformation. This study aims to establish in vitro multiplication, transformation, and gene editing systems in tomatoes by using cotyledon explants. Cotyledon explants were placed on the MS medium suppor [...]

1633 9901

Open Access Review

The Effectiveness of Using Progressive Muscle Relaxation Techniques on Quality of Life, Stress, And Anxiety Among Acute Myocardial Infarction: A Systematic Review

Ala'a A. AI-yyan ,

Ayat A. ELayan and

Mohammad Saleh

Received: 28 February 2024; Published: 16 June 2024; doi: 10.21926/obm.neurobiol.2402226

Abstract

The progressive muscle relaxation technique (PMRT) is an active method that is defined as a technique through which individuals gradually cause a feeling of quietness and coolness by actively contracting and loosening specific muscle groups. The purpose of this study was to review the effectiveness of using progressive muscle relaxation techniques on quality of life, stress, and anxiety levels among Acute Myocardial Infarction patients. A systematic review of randomized controlled trials (2013-2023). Databases of P [...]

2333 24074

Open Access Original Research

Integrated Web Application (Snips2HLA-HsG) Development for Sample Preparation and Model Creation for HLA Allele Prediction with the SNP Data Using HIBAG Package of Bioconductor and R Programming

Balamurugan Sivaprakasam and

Prasanna Sadagopan

Received: 24 December 2023; Published: 14 June 2024; doi: 10.21926/obm.genet.2402243

Abstract

The present study introduces Snips2HLA-HsG, an integrated application designed for SNP genotype analysis and HLA allele type prediction. Leveraging attribute bagging, a powerful ensemble classifier technique from the Bioconductor HIBAG package, Snips2HLA-HsG offers a comprehensive response for genetic analysis. Accessible via https://snips2hla.shinyapps.io/hla_home/, the application distinguishes itself by prioritizing user-friendliness and integrating all-purpose functionalities, including sample preparation, mode [...]

1269 8630

Open Access Review

llmenite and Biomass Composite Nanomaterials - A Review

Charitha Thambiliyagodage ,

Madara Jayanetti ,

Geethma Ekanayake ,

Amavin Mendis ,

Heshan Liyanaarchchi and

Supuni Wijayawardana

Received: 10 April 2024; Published: 13 June 2024; doi: 10.21926/cr.2402006

Abstract

Ilmenite is a mineral whose crystallinity can be altered by chemical treatment, producing TiO2 and iron and titanium-based metal nanocomposites, which are applicable mainly for photocatalysis. Porous and crystalline biomass-derived carbon materials include graphene oxide, reduced graphene oxide, graphitic carbon nitride, catalytically graphitized sucrose and chitosan, and activated carbon. Ilmenite-based metal oxides coupled with biomass-based carbon materials are effective in environmental remediation, especially [...]

1760 9781

Open Access Short Communication

Therapeutic Termination of Pregnancy and Paternal Mental Outcomes

Rodolfo Pessina ,

Fabrizia Colmegna ,

Massimo Clerici and

Ester di Giacomo

Received: 26 December 2023; Published: 13 June 2024; doi: 10.21926/obm.icm.2402034

Abstract

Therapeutic termination of pregnancy (TToP) is performed for maternal health risks or severe fetal malformations. Research focuses on women's psychopathological outcomes after TToP, noting that 10-22% of women experience psychiatric disorders, especially depressive symptoms and post-traumatic stress disorder (PTSD). However, little is known about paternal mental outcomes. This study analyzed biological fathers' mental health at a 1-year follow-up after TToP. Results indicate biological fathers show no alarming psyc [...]

999 4492

Open Access Review

Melatonin As a Protective Agent Against Environmental Stresses: A Review into Its Molecular Regulation in Plants

Buti Obaid Saeed Alfalahi ,

Imane Lamdjad ,

Mustafa Alnujaifi ,

Noaman Atallah Alheety and

Abdul Qayyum

Received: 05 February 2024; Published: 12 June 2024; doi: 10.21926/obm.genet.2402242

Abstract

Understanding the impact of melatonin (N-acetyl-5-methoxytryptamine) on plant gene expression is crucial for unlocking its full potential as a tool for crop improvement and stress tolerance. Melatonin has emerged to have several influences on the transcriptional activity of numerous genes, helping to orchestrate plant responses to environmental cues. Furthermore, it has been shown that melatonin signaling pathways control downstream gene expression to ensure proper plant growth and development. Therefore, clearing [...]

1231 8603

Open Access Original Research

The Screening Strategies Used to Establish Egyptian Women Entrepreneurs’ Attitudes towards Genetic Technology

Nadia A. Abdelmegeed Abdelwahed

Received: 12 March 2024; Published: 12 June 2024; doi: 10.21926/obm.genet.2402241

Abstract

In this quantitative study, the researcher examined the screening strategies used to establish Egyptian women entrepreneurs' attitudes toward genetic technology. Using a questionnaire, the researcher collected data from 318 Egyptian women entrepreneurs. From applying the path analysis through Analysis of Moment Structures (AMOS) version 26.0, this study’s findings demonstrate genomic knowledge’s positive effect on attitudes towards genetic technology (β = 0.176; p = 0.003). The path analysis shows that, on the one [...]

1053 4864

Open Access Review

Phytoremediation: A Sustainable Approach to Combat Soil Salinity

Rakesh Chandra Nainwal ,

Premchand Chaurasiya ,

Arun Kumar ,

Mohan Singh ,

Devendra Singh and

Shri Krishna Tewari

Received: 14 March 2024; Published: 12 June 2024; doi: 10.21926/aeer.2402015

Abstract

Soil salinization is a significantconstraint affecting the productivity of agricultural land worldwide. This led to the abandoning of the production of farmcrops on colossalland. Soil salinity inversely affects seed germination and plant growth and influences the plant’s biological activities like photosynthesis, respiration, plant metabolism, enzymatic activities, hormone regulation, etc. Therefore, efforts are being made to bring the saline soil under cultivation by improving itthrough a proper drainage sys [...]

2204 16961

Open Access Research Article

Developing a Compassion Focused Supervision Model for Senior Leaders in Education

Charles Heriot-Maitland and

Jo Taylor

Received: 22 March 2024; Published: 11 June 2024; doi: 10.21926/obm.icm.2402033

Abstract

This article describes the development and delivery of a novel model of supervision for senior teachers in schools, informed by Compassion Focused Therapy (CFT). It explores whether this model can be considered acceptable and valuable to senior teachers, and is able to be delivered by multiple supervisors using a manual. Surveys, interviews, and focus groups were used to gather feedback about the value and impact of the supervision. Data were gathered from 39 senior teachers across three phases to assess feedback o [...]

1691 9586

Open Access Original Research

Molecular Cytogenetic Characterization of Rare but Repeatedly Observed Translocations

Ana Luísa Teixeira Fontes ,

Niklas Padutsch ,

Stefanie Kankel and

Thomas Liehr

Received: 15 April 2024; Published: 11 June 2024; doi: 10.21926/obm.genet.2402240

Abstract

Balanced chromosomal rearrangements, including translocations, contribute to infertility, repeated abortions, and/or genetically imbalanced offspring in corresponding carriers. A translocation is usually considered a unique, de novo, or familial event. Besides, some translocations have also been shown to develop multiple times with slightly different or even identical breakpoints; for others, founder effects have been suggested. Here, two known recurrent translocations [t(11;22)(q23.3;q11.21) and der(X)t(X; Y)(p22. [...]

1066 4974

Open Access Review

Human Health Impact of Municipal Solid Waste Mismanagement: A Review

Ernesto de Titto and

Atilio Savino

Received: 22 December 2023; Published: 11 June 2024; doi: 10.21926/aeer.2402014

Abstract

Management of municipal solid waste (MSW) is frequently not properly performed. Whenever this happens, those working in the different stages of the process, as well as residents close to the dumps, face health risks. Here, we revised the documented evidence of emissions liberated during MSW management and associated health problems to investigate if systematic and reproducible relationships can be established. Besides substances released during collection and transportation, various toxic substances, predominantly [...]

3686 38394

Open Access Case Report

Management of Calcareous Corneal Degeneration from Medication Washout to Corneal Transplantation. Case Series and Review of the Literature

Filippo Lixi ,

Benedetta Pintus and

Giuseppe Giannaccare

Received: 27 February 2024; Published: 07 June 2024; doi: 10.21926/obm.transplant.2402218

Abstract

Calcareous corneal degeneration is a rare disease characterized by calcium phosphate deposition into the deep corneal layers. Corneal calcification has a multifactorial origin and is associated with various systemic and ocular conditions. Several treatment options showed promising results in the management of this disorder. Herein, two cases of calcareous degeneration occurring postoperatively in patients undergoing surgery for retinal detachment (case #1) and glaucoma (case #2) were reported. Despite normal serum [...]

953 8124

Open Access Original Research

Prescribed Medicinal Cannabis for the Treatment of Chronic Pain Comorbid with Depression: Real World Evidence from Project Twenty21

Alkyoni Athanasiou-Fragkouli ,

Michael T Lynskey ,

Anne Katrin Schlag and

David J Nutt

Received: 01 March 2024; Published: 05 June 2024; doi: 10.21926/obm.icm.2402032

Abstract

Chronic pain is one of the most common conditions for which people seek treatment with cannabis-based medicinal products (CBMPs) and there is mounting real world evidence that CBMPs are safe and effective in treating pain. Many people with chronic pain also experience major depression and it is unknown whether pain patients with major depression derive equal benefit from CBMPs as those who are not depressed since comorbidities are usually an exclusion factor in RCTs. This study aimed to investigate whether patients [...]

1764 37060

Open Access Original Research

Circulating lncRNAs HOTTIP and HOTAIR as Potential Biomarkers in Crigler-Najjar Syndrome: A Preliminary Report from Shiraz Liver Transplant Research Center

Nasrin Motazedian ,

Masoud Mokhtari ,

Negar Azarpira ,

Kimia Falamarzi ,

Mohsen Mohammadi ,

Seyed Mohsen Dehghani ,

Sarina Pourjafar ,

Maryam Ataollahi ,

Elaheh Esfandiari ,

Mahdokht Hossein-Aghdaie ,

Seyed Ali Malekhosseini ,

Tayebeh Kazemi and

Mahintaj Dara

Received: 05 May 2024; Published: 04 June 2024; doi: 10.21926/obm.transplant.2402217

Abstract

Crigler-Najjar syndrome (CNS) is a rare autosomal recessive disorder characterized by impaired bilirubin metabolism, leading to neurotoxic unconjugated bilirubin accumulation. Liver transplantation remains the only effective treatment, highlighting the need for novel diagnostic and therapeutic approaches. Long non-coding RNAs (lncRNAs) have emerged as potential biomarkers in various diseases, including cancer. This study aimed to evaluate the expression of lncRNAs HOTTIP and HOTAIR in CNS patients and healthy contr [...]

1121 6097

Open Access Original Research

Is Stimulant Treatment in Children and Adolescents with Mood Dysregulation Associated with Adverse Outcomes?

Hannah O'Connor ,

Joseph Biederman ,

Maura DiSalvo ,

Gagan Joshi ,

Stephen V. Faraone and

Janet Wozniak

Received: 25 January 2024; Published: 04 June 2024; doi: 10.21926/obm.icm.2402031

Abstract

The aim of this paper is to examine effects of stimulant treatment in children and adolescents with high levels of emotional dysregulation in a psychiatric outpatient clinic. Subjects were referred children and adolescents 6-17 years of age who presented to a child psychiatric outpatient clinic between September 2016-November 2021 and received a prescription for a stimulant medication. Children were stratified into those with low and high levels of emotional dysregulation as defined by an aggregate T-score of <1 [...]

1189 7264

Open Access Research Article

Spin Entanglement – A Unifying Principle for Superconductors and Molecular Bonding

Paul O'Hara

Received: 20 December 2023; Published: 03 June 2024; doi: 10.21926/rpm.2402012

Abstract

The spin-statistics theorem is generalized to include quantum entanglement. Specifically, within the context of spin entanglement, we prove that isotropically spin-correlated (ISC) states must occur in pairs. This pairing process can be composed of parallel or anti-parallel states. Consequently, the article proposes using ISC states as a unifying principle to explain better Bose-Einstein condensates, the theory of superconductivity, and molecular and atomic orbitals, all of which involve a pairing process. The theo [...]

1052 8247

Open Access Original Research

Is Donation after Circulatory Determination of Death in Japan Uncontrolled or Controlled?

Tatsuya Kin ,

Hirofumi Noguchi and

Atsushi Kawaguchi

Received: 15 February 2024; Published: 03 June 2024; doi: 10.21926/obm.transplant.2402216

Abstract

Using donation after circulatory determination of death (DCD) donors has been shown to be a potential means of increasing the number of donors for organ transplantation. The purpose of this study was to examine the published practice of DCD in Japan to properly define their practice as controlled or uncontrolled. Through the Web of Science database, we systematically searched articles describing uncontrolled DCD, controlled DCD or Maastricht classification. A total of 12 articles (ten articles related to kidney, on [...]

1006 6961

Open Access Research Article

Reflective Evaluation of Next-Generation Sequencing Data during Early Phase Detection of the Delta Variant

Upasana Ramphal ,

Derek Tshiabuila ,

Yajna Ramphal ,

Jennifer Giandhari ,

Carel van Heerden ,

Cheryl Baxter ,

Stephanie van Wyk ,

Sureshnee Pillay ,

Oluwakemi Laguda-Akingba ,

Eduan Wilkinson ,

Richard Lessells and

Tulio de Oliveira

Received: 01 March 2024; Published: 30 May 2024; doi: 10.21926/obm.genet.2402239

Abstract

During the SARS-CoV-2 pandemic, next-generation sequencing (NGS) technologies like the Ion Torrent S5 and Illumina MiSeq, alongside advanced software, improved genomic surveillance in South Africa. This study analysed anonymized samples from the Eastern Cape using Genome Detective and NextClade, showing Ion Torrent S5 and Illumina MiSeq success rates of 96% and 94%, respectively. The study focused on genomic coverage (above 80%) and mutation detection (below 100), with the Ion Torrent S5 achieving 99% coverage comp [...]

2319 8695

Open Access Original Research

The Multigenerational Legacy of Diabetes and Illness Perception: Influence on Older Adult’s Stigma

Melissa Scollan-Koliopoulos ,

Donna Naturale ,

Brynn Mahurter ,

Sara Curren and

Ryan J. Koliopoulos

Received: 03 February 2024; Published: 29 May 2024; doi: 10.21926/obm.geriatr.2402280

Abstract

There is not enough information regarding the impact of stigma associated with a. diagnosis of diabetes in aging older adults. Perceptions of diabetes are passed down generationally and may be influenced by mainstream societal perceptions at the time the perception is shaped. This is known as a multigenerational legacy of diabetes for those with whom the perceptions are shaped within families when a hereditarily predisposed condition occurs. In this study, participants over the age of (n = 88) 60 years old were adm [...]

1190 5689

Open Access Review

Biotechnology Innovation in Do-It-Yourself (DIY) Gene Editing: A Call for a New Regulatory Framework

Alessandro Stasi and

Onnida Thongpravati

Received: 04 March 2024; Published: 29 May 2024; doi: 10.21926/obm.genet.2402238

Abstract

The expansion of do-it-yourself (DIY) gene editing, facilitated by Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) technology, has catalyzed a significant shift in scientific research and biotechnology innovation. This movement is propelled by a community-driven approach that challenges the traditional confines of scientific exploration, allowing amateur scientists to perform sophisticated biological experiments. While this democratization fosters inclusivity and accelerates innovation, it simult [...]

4232 23119

Open Access Review

Bacteriophages Therapy: Exploring Their Promising Role in Microbiome Modulation and Combatting Antibiotic Resistance

Ahmad R. Alsayed and

Andi Dian Permana

Received: 28 February 2024; Published: 28 May 2024; doi: 10.21926/obm.genet.2402237

Abstract

Bacteriophages, or phages, are viruses that infect bacteria, exhibiting specificity towards particular bacterial strains. Despite being overshadowed by traditional antibiotics in the West, interest in phage therapy has resurged due to the escalating antimicrobial resistance crisis. Understanding phage biology, selection, production, and pharmacology is crucial for their clinical application. Phages interact intricately with the human microbiome, influencing bacterial populations and potentially offering therapeutic [...]

1772 11069

Open Access Original Research

Sustainable Hospital Waste Management Practices in the Western Province of Sri Lanka: Problems and Prospects

R. Lalitha S. Fernando and

M.K.M. Natharka Rushan

Received: 25 December 2023; Published: 28 May 2024; doi: 10.21926/aeer.2402013

Abstract

Ensuring the sustainability of hospital waste management practices has become a burning issue. Due to the growing population coinciding with rapid urbanization and industrialization, practicing sustainable methods of medical waste management is an urgent requirement. Like other developing countries, Sri Lanka also faces various difficulties when dealing with high-risk hospital waste material, spreading diseases rapidly and making the environment unclean. Thus, moving towards sustainable hospital waste management ha [...]

2773 22994

Open Access Review

Trauma in Schools: A Review of the Impact of Childhood Trauma and Assessment of a Potential Intervention

Emily Smith Schafer

Received: 02 March 2023; Published: 24 May 2024; doi: 10.21926/obm.icm.2402030

Abstract

According to the National Survey of Children’s Health (NSCH), nearly 30 million children in the United States have experienced one or more types of significant childhood trauma. In the average public school, this statistic translates to as many as half of the students in a given teacher’s classroom. Children exposed to the toxic stress of trauma often experience negative consequences that affect their academic, psychological, socioemotional, and behavioral health. To aid educators in addressing this reality, trauma [...]

2829 22358

Open Access Original Research

The Significance of Key Proteins in the RAS Signaling Pathway: Implications for Cancer and Therapeutic Targets

Emad Fadhal

Received: 18 January 2024; Published: 24 May 2024; doi: 10.21926/obm.genet.2402236

Abstract

The RAS signaling pathway is a crucial cell transduction pathway central to transmitting signals from outside the cell to the cell nucleus and influencing fundamental biological mechanisms like cell growth, division, and specialization. This signaling pathway has recently received much attention in scientific research because of its involvement in various diseases, especially carcinogenesis. Our study identified the significance of crucial proteins in the RAS signaling cascade in cancer development and progression. [...]

1279 8584

Open Access Review

Enhancing University Students’ Mental Health under Artificial Intelligence: Principles of Behaviour Therapy

Mubashir Zafar

Received: 13 March 2024; Published: 24 May 2024; doi: 10.21926/obm.neurobiol.2402225

Abstract

The increasing prevalence of mental health issues among university students has become a growing concern globally. This review explores the potential of Artificial Intelligence (AI) integrated with principles of behaviour therapy to address mental health challenges among university students. The paper examines how AI technologies, including chatbots, virtual reality, and machine learning algorithms, can be harnessed to provide accessible, personalized, and effective mental health interventions. Furthermore, it disc [...]

1780 17023

Open Access Original Research

Enhancing Therapist Courage: Feasibility and Changes in Distress Tolerance and Equanimity Following Martial Arts-Based Radically Embodied Compassion Workshops

Syd Hiskey and

Neil E Clapton

Received: 07 April 2024; Published: 21 May 2024; doi: 10.21926/obm.icm.2402029

Abstract

The work of psychotherapy demands much of those who engage in it. Compassion provisioned by therapists requires varying competencies, yet remains a highly embodied and enactive endeavour. Therapist skill can be cultivated in this area and enhanced through a variety of body-mind trainings, including various forms of therapist personal practice. However, much clinical training/continued professional development centres on education workshops, emphasising knowledge above skill. Given this we present feasibility data f [...]

1394 7549

Open Access Original Research

Assessing the Factor Structure and Construct Validity of the Beck Depression Inventory (BDI-II) in a Korean Preschool Teacher Sample

Yang Eun Kim and

Boram Lee

Received: 07 March 2024; Published: 21 May 2024; doi: 10.21926/obm.neurobiol.2402224

Abstract

Preschool teachers are at high risk of depression. Therefore, emphasis should be placed on evaluating a valid and reliable instrument to measure depressive symptomatology for this population. One such promising instrument is the Beck Depression Inventory (BDI-II), a 21-item self-report measure designed to assess the presence and severity of depression. Although the tool’s psychometric properties have been analyzed in different samples, they have not been validated with a Korean preschool teacher sample. Hence, this [...]

1636 16438

Open Access Original Research

Effect of Hydrotherapy and Physical Activity on Uric Acid and Nitric Oxide Concentrations in Serum Samples

Ana Valado ,

Márcia Morais ,

Stephanie Fortes ,

Joana Rosado ,

João Paulo Figueiredo and

Armando Caseiro

Received: 20 November 2023; Published: 21 May 2024; doi: 10.21926/obm.icm.2402028

Abstract

Hydrotherapy is highly recommended for older adults because it offers warmth and support, so people with pain or reduced mobility and balance can move and exercise more freely compared to regular physical activity. The high plasma antioxidant capacity of uric acid in neutralizing oxidative species and the importance of nitric oxide (NO) in vasodilation and inflammatory response are relevant in older adults. This work aimed to evaluate hydrotherapy's effect on uric acid and NO concentrations in a population aged ≥ 6 [...]

1393 7987

Open Access Original Research

Cryptic Resilience: Decoding Molecular Networks in Pearl Millet for Enhanced Heat Stress

Faten Dhawi

Received: 20 February 2024; Published: 20 May 2024; doi: 10.21926/obm.genet.2402235

Abstract

Pearl millet (Pennisetum glaucum), a vital cereal crop renowned for its drought tolerance, is a cornerstone for smallholder farmers in arid and semi-arid regions, ranking as the fifth most significant cereal globally. Despite its resilience, the molecular mechanisms underlying its tolerance to heat stress remained elusive. To address this knowledge gap, we subjected ten-day-old pearl millet seedlings to an unprecedented temperature of 50°C for 60 seconds. Subsequent next-generation RNA sequencing aimed to unrav [...]

2020 8945

Open Access Original Research

Application of Simulation-Based Metrics to Improve the Daylight Performance of a Secondary School, An Approach for Green Building Designers and Architects

Salah Vaisi ,

Honia Modares Gorji and

Narmin Shafei

Received: 07 January 2024; Published: 17 May 2024; doi: 10.21926/aeer.2402012

Abstract

Visual comfort affects the quality of classrooms as well as student learning. A practice-oriented approach discovers how the gap between academic research and its application in building design can be addressed. Nevertheless, the physical characteristics design of daylighting systems, including window sizes, shapes, dimensions, and materials, are considered fundamental challenges for their practicability. In this study, the physical characteristics design of daylighting systems, including window sizes, shapes, dime [...]

2694 23105

Open Access Editorial

Mechanisms of Laser Acupuncture – Hypotheses and Evidence

Gerhard Litscher

Received: 14 May 2024; Published: 15 May 2024; doi: 10.21926/obm.icm.2402027

Abstract

Laser acupuncture, a rising complementary therapy, applies a low-intensity laser to acupuncture points, yet its underlying mechanisms remain unclear. Proposed hypotheses include modulation of cellular signaling, tissue repair, and immune modulation. Laser acupuncture may stimulate energy flow, neurotransmitter release, cellular changes, immune regulation, and neuroendocrine activity. Additionally, the biophoton theory suggests an involvement of ultra-weak photon radiation from cells. Litscher et al. explore these m [...]

1564 9688

Open Access Original Research

A Remarkable Pt Doped CNT Catalyst as a Double Functional Material: Its Application for Hydrogen Production and Supercapacitor

Tülin Avcı Hansu

Received: 25 December 2023; Published: 15 May 2024; doi: 10.21926/cr.2402005

Abstract

In this study, by producing bifunctional material, hydrolysis, and supercapacitor applications were investigated. The carbon nanotube-supported Pt catalyst was prepared using the sodium borohydride (NaBH4) reduction. Surface characterization of the synthesized Pt/CNT catalyst was performed using scanning electron microscopy-energy dıstrıbutıon X-ray spectrometer (SEM-EDX), X-ray diffraction (XRD), and transmission electron microscopy (TEM). Hydrolysis experiments were performed after deciding on the appropriate ato [...]

1573 7875

Open Access Original Research

The Effect of the Addition of Titanium Dioxide on Silicone Self-Adhesive Tapes

Adrian Krzysztof Antosik ,

Karolina Mozelewska and

Marcin Bartkowiak

Received: 29 February 2024; Published: 13 May 2024; doi: 10.21926/jept.2402012

Abstract

The investigation aimed to delve into the intricate relationship between the presence of titanium dioxide and the resulting alterations in the adhesive's behavior under different conditions. The focus extended beyond mere observation to understand how these additives interact with the adhesive matrix, potentially imparting beneficial attributes. Notably, the study delved into the optimization of thermal stability, the extension of the adhesive's functional lifespan, and the mitigation of shrinkage tendencies. This [...]

1410 8354

Open Access Original Research

Building Blocks for an Energy Transition

Gilbert Ahamer

Received: 07 December 2023; Published: 13 May 2024; doi: 10.21926/jept.2402011

Abstract

The present need for an energy transition in the wake of a global climate catastrophe led to the “EU green deal” which requires a transition of the energy system in all countries. This study aimis survey aims to identify strategies within such an energy transition based on global trend analyses and reports on available technologies for implementation. Based on a literature analysis of over 300 pieces (of feasibility studies and technology implementation reports with a focus on Central Europe) and a statistical anal [...]

1427 10970

Open Access Review

The Impact of Wellbeing Interventions on the Anxiety Levels of Children Attending Low-Income Schools: A Systematic Literature Review

Tracy O'Halloran ,

Jennifer Symonds and

Linda Bhreathnach

Received: 02 November 2023; Published: 11 May 2024; doi: 10.21926/obm.icm.2402026

Abstract

This systematic review examined the impact of wellbeing interventions on the anxiety levels of children attending low-income schools. Studies, published between January 2000 and April 2022, were included if they had samples of school aged children attending low-income schools who were given a universal school-based wellbeing intervention. Ten databases were searched systematically to identify 542 records. After title and abstract screening, 43 records remained for full text screening, and of these studies, 10 met i [...]

1634 7570

Open Access Short Review

Simiao Powder as an Effective Remedy for Gout

Anna Koczwara ,

Lingfan Jiang and

Shasha Zheng

Received: 29 November 2023; Published: 11 May 2024; doi: 10.21926/rpn.2402009

Abstract

Gout is an increasing metabolic disease due to the buildup of uric acid. The buildup of uric acid due to inadequate excretion leads to uric acid crystal formation. Treatment for gout aims to eliminate the uric acid crystal formation so that inflammation decreases. Traditional gout medication is usually allopurinol, but increasing studies have proven that herbal remedies may be promising. Over the past few years, studies have demonstrated that Simiao powder, a traditional Chinese medicine (TCM), is more effective th [...]

3203 51912

Open Access Review

Advances in Managing Infections in Lung Transplantation: A Review

Shourjo Chakravorty and

Ashka Patel

Received: 21 November 2023; Published: 10 May 2024; doi: 10.21926/obm.transplant.2402215

Abstract

Transplanted lung allografts are particularly susceptible to infection among SOT due to the constant exposure to the environment, aggressive immunosuppressive strategies, and impaired clearance mechanisms after denervation of the transplanted lung. Though prophylactic antimicrobial, antifungal, and antiviral regimens are used as preventive strategies to mitigate the risk of infection, complications related to allograft infection remain one of the primary causes of morbidity and mortality after lung transplantation. [...]

1089 7463

Open Access Review

Red Algae Compounds: Potential Neuroprotective Agents for Neurodegenerative Disorders

Leonel Pereira and

Ana Valado

Received: 06 March 2024; Published: 10 May 2024; doi: 10.21926/obm.neurobiol.2402223

Abstract

This review explores the potential of compounds derived from red algae (Rhodophyta) as promising neuroprotective agents for treating neurodegenerative disorders. Red algae, abundant in marine environments, contain bioactive compounds with diverse chemical structures and functionalities. Sulfated polysaccharides, primarily agar and carrageenans, stand out as the predominant and widely utilized compounds derived from red algae. Additionally, red algae harbor a spectrum of potential molecules such as essential fatty a [...]

2237 15386

Open Access Review

Exploration of Dementia Help Seeking Behaviours Amongst UK South Asian Communities: A Systematic Review

Shashya Wijesinghe and

Elizabeta B. Mukaetova-Ladinska

Received: 03 March 2024; Published: 10 May 2024; doi: 10.21926/obm.geriatr.2402279

Abstract

In the UK, 25,000 people from ethnic minority background live with dementia. Although dementia associated risk factors are common amongst South Asians, they tend to present at services later and when in crisis. This review explores UK South Asian communities perception of dementia to understand factors impacting their decision to seek help. Search terms assisted by the PICO strategy were inputted into five databases and ten qualitative papers identified. Meta-ethnography methodological framework was implemented for [...]

1344 10093

Open Access Opinion

Prevention of Drug Resistant Epilepsy and Developmental Epileptic Encephalopathy: Preventative Vigabatrin Treatment in Tuberous Sclerosis Complex and the Case for Fenfluramine Treatment of Children with Newly Diagnosed Dravet Syndrome

Amanda Pong and

Pavel Klein

Received: 15 February 2024; Published: 08 May 2024; doi: 10.21926/obm.genet.2402234

Abstract

Tuberous sclerosis complex (TSC) is caused by mutations of hamartin (TSC1) or tuberin (TSC2) resulting in disinhibition of the mTOR pathway of cellular proliferation and differentiation and severe neurocognitive impairment, intractable epilepsy and tumors. Epilepsy develops in ~90% folllowed by drug-resistant epilepsy (DRE). Recently, prevention of DRE and developmental encephalopathy was shown to be possible in TSC using early administration of vigabatrin. For the first time, medical treatment successfully prevent [...]

1152 6604

Open Access Original Research

Frequency of Unplanned Readmissions Following Lung Transplantation During the SAR-COV-2 Pandemic When Hospital Resources Were Strained

Justin Cole ,

Eugene Golts ,

Michael Bernales ,

Dina Shirazi ,

Deepa Kurup ,

Sarah Golts ,

Gordon Yung ,

Aarya Kafi ,

Christine M. Lin ,

Travis Pollema and

Kamyar Afshar

Received: 19 October 2023; Published: 08 May 2024; doi: 10.21926/obm.transplant.2402214

Abstract

Despite the concerted efforts by lung transplant recipients (LTR) and their medical teams, hospital readmissions are common in the first year following transplantation. Reasons for unplanned readmissions include allograft rejection, infections, and respiratory failure before the SARS-COV-2 pandemic. Clinical predictors of readmissions have changed over time with the higher risk factors of acceptable criteria for recipients and donors. We aimed to assess more recent readmission rates based on group classifications t [...]

1855 6944

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