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Open Access Review

Enzymes in Poly(Butylene-Succinate) Industry: An Overview on Synthesis Routes and Post-Processing Strategies

Received: 16 June 2023;  Published: 08 November 2023;  doi: 10.21926/cr.2304026

Abstract

This paper will present some sectors in which enzymes can replace traditional catalysts in poly(butylene-succinate) industry, emphasizing the green chemistry aspects associated with these newer strategies.

1911 14343

Open Access Original Research

Technical Analysis of Sawdust-to-Power: A Paradigm Shift in Waste Management in a Typical Developing Economy

Received: 01 August 2023;  Published: 08 November 2023;  doi: 10.21926/jept.2304033

Abstract

The proper management of sawdust is critical to socioeconomic development. In this research, waste-to-energy has been proposed to utilize sawdust in selected timber markets in Port Harcourt, namely, Illoabuchi Timber Market, Marine Base Timber Market, and Mile 3 Timber Market. A quantitative approach has been taken to estimate the sawdust generation, energy potential, power generation capacities, and pollutant reduction of indiscriminate combustion of sawdust. The findings suggest that, annually, 171 ktons, 42 kton [...]

1790 12507

Open Access Review

Rehabilitation of Chronic Pain in Post-Critical Care Patients. A Narrative Review

Received: 11 April 2023;  Published: 08 November 2023;  doi: 10.21926/obm.neurobiol.2304194

Abstract

Chronic pain in post-critical care patients is a multifaceted issue with profound implications for patient well-being and quality of life. This review aims to address the rehabilitation of patients who suffer from chronic pain following discharge from the intensive care unit (ICU). Despite growing awareness of the prevalence and impact of this condition, significant gaps in knowledge persist regarding the optimal rehabilitation strategies for these patients. To conduct this study, an extensive literature search was [...]

1401 9143

Open Access Review

Building Resilience in Students: Managed and Minimised Stress in Students

Received: 07 March 2023;  Published: 07 November 2023;  doi: 10.21926/obm.neurobiol.2304193

Abstract

Stressful events in students' and teachers' personal, academic, and professional lives are widespread. The paper discusses many effective methods and techniques for correcting and preventing stress that are simple to learn and practice. They give good results in working with children, adolescents, and youths in training and education. Some practices are more complex and require more attention and effort to understand and master them, but they also have broader capabilities in various situations. Therefore, training [...]

3221 19764

Open Access Original Research

Nature Connection, Mindfulness, and Wellbeing: A Network Analysis

Received: 15 September 2022;  Published: 06 November 2023;  doi: 10.21926/obm.icm.2304050

Abstract

Relationships between nature connection, mindfulness and wellbeing have been observed through nature based therapeutic interventions, where mindfulness and nature appear to reciprocally influence each other in relation to wellbeing and is potentially consistent with attention restoration theory. However, previous studies have relied on examining nature based interventions rather than the role of nature connection in everyday lives. This investigation explored the relationship between nature connection, mindfulness, [...]

1645 13124

Open Access Review

HLA Typing and Donor-Specific Antibody Screening in Kidney Transplantation: Bridging the Past to the Future

Received: 15 March 2023;  Published: 06 November 2023;  doi: 10.21926/obm.transplant.2304201

Abstract

Human leukocyte antigens (HLA) are unique proteins expressed on the surface of human cells, playing a pivotal role in the immune system, particularly in the contexts of infection, cancer, and transplantation. The widespread adoption of HLA typing methods has become an essential component in assessing donor-recipient compatibility, a crucial limiting factor in solid organ transplantation. In general, the greater the disparity between a donor's and recipient's HLA types, the higher the likelihood of provoking an allo [...]

1622 13325

Open Access Short Communication

Low-Frequency Oscillations for Nonlocal Neuronal Coupling in Shared Intentionality Before and After Birth: Toward the Origin of Perception

Received: 09 May 2023;  Published: 02 November 2023;  doi: 10.21926/obm.neurobiol.2304192

Abstract

The theoretical study observes literature to understand whether or not low-frequency oscillations can simultaneously alter the excitability of neurons from peripheral nervous subsystems in different individuals to provide Shared Intentionality in recipients (e.g., fetuses and newborns) and what are the attributes of ecological context for Shared Intentionality. To grasp the perception of objects during environmental learning at the onset of cognition, a fetus needs exogenous factors that could stimulate her nervous [...]

1627 18537

Open Access Original Research

Preparation & Characterization of Polyvinyl Alcohol-Sodium Alginate-Starch Based Hydrogel by Gamma Radiation and Its Application for the Treatment of Dye Containing Water

Received: 04 September 2023;  Published: 02 November 2023;  doi: 10.21926/aeer.2304048

Abstract

Hydrogels are three-dimensional, hydrophilic networks of polymers with a high water absorption capacity. We investigated the removal of monovalent cationic dye, methylene blue, from aqueous solutions by a polyvinyl alcohol/Sodium alginate/Starch mix hydrogel to discover a solution to the environmental waste-water problem. By applying a gamma radiation dose from a Co-60 source without adding a hazardous cross-linker, a novel PVA/SA/Starch mix hydrogel was synthesized. The effects of factors like irradiation dose and [...]

1696 9981

Open Access Research Article

Na+ Mobility in PEO-Based Composite Solid-State Electrolytes by NMR

Received: 04 August 2023;  Published: 02 November 2023;  doi: 10.21926/jept.2304032

Abstract

Charge transfer and mobility are essential for electrochemical processes in batteries, which need to be understood in detail for optimization, especially in the case of all-solid-state batteries. Wide line NMR is well-known in solid-state NMR and allows the quantification of ion mobility in ordered crystalline and amorphous structures. Temperature-dependent 23Na-NMR is sensitive to ion mobility via longitudinal relaxation, but also via line analysis and transverse relaxation. As 23Na is a spin 3/2 nucleus, 23Na-NMR [...]

2923 11750

Open Access Research Article

Peri-transplant Treatment with Ceftaroline in Kidney Transplant Recipients at Risk of Donor-derived MRSA Infections: A Case Series

Received: 19 July 2023;  Published: 01 November 2023;  doi: 10.21926/obm.transplant.2304200

Abstract

The rising prevalence of MDR pathogens has a significant impact on the recipients' outcome, as this increases the risk of graft complications and makes the management of the peri-transplant phase more difficult. Among the different MDR germs, Methicillin-resistant Staphylococcus aureus (MRSA) represents one of the most frequently isolated pathogens. We report for the first time the off-label use of Ceftaroline in six kidney transplant recipients with donor peritransplantation MRSA bacteremia at the Division of Kidn [...]

1295 6764

Open Access Research Article

Phytomodification Effects of Visceral Lymph Node Aging

Received: 09 July 2023;  Published: 01 November 2023;  doi: 10.21926/obm.geriatr.2304257

Abstract

Lymph nodes are prioritized in protecting and ensuring endoecological safety at different periods of life, especially in retirement age. It destabilizes the structure and function of the lymphatic system and organs when aging increases the risk of comorbid conditions. This is a sign of age-related pathology. Improving lymph node function is an essential task in integrating gerontology and lymphology. The solution to this problem is possible with the help of a phytotherapeutic agent, which involves the evaluation of [...]

1144 6282

Open Access Research Article

Possibilities of Predicting a Person's Substance Use Behaviour and Mental Health Through Social Media in a COVID-19 Crisis Context

Received: 18 July 2023;  Published: 01 November 2023;  doi: 10.21926/obm.icm.2304049

Abstract

The negative psychological consequences of the COVID-19 pandemic and the forced isolation of a large proportion of people worldwide have demonstrated the need to develop ways and technologies to reduce the effects of sudden threats of this type. The basis of any practical work to minimize the negative psychological consequences of the COVID-19 pandemic associated with substance use is the monitoring and diagnosis of the psychological resources of the individual. The article aims to show the possibilities of predict [...]

1126 5740

Open Access Case Report

Progressive Pseudo-Rheumatoid Dysplasia a Rare Genetic Musculoskeletal Condition Causing Crippling Disability in a Young Boy- a Case Report

Received: 05 July 2023;  Published: 30 October 2023;  doi: 10.21926/obm.genet.2304202

Abstract

Progressive pseudo-rheumatoid dysplasia (PPRD) is an uncommon genetic condition inherited in an autosomal recessive mode caused by a mutation in the WNT1-inducible signaling pathway protein 3 (WISP3) located on chromosome 6q21. In this condition, the articular cartilage gradually deteriorates, causing severe discomfort, stiffness, and joint deformities with a relatively high prevalence in Middle Eastern countries. Camptodactyly and platyspondyly are the standard features found in this condition. We present a very y [...]

1257 7202

Open Access Concept Paper

Four Decades of Newborn Screening: A Historical Perspective of Laboratory Practices

Received: 21 March 2023;  Published: 30 October 2023;  doi: 10.21926/obm.genet.2304201

Abstract

The personal experience of 36 years in charge of the Newborn Screening Laboratory in Galicia and the consequences of the recent advancement of sampling from 3 days to 24 hours of the newborn's life are reviewed. The implication in the results of the assay of reducers in urine with the Mandelin reagent and its alternatives is commented. The implication in the effects of TSH in blood and the possible ways of dealing with the situation. Since 1978, the Newborn Screening Program in Galicia has maintained the urine samp [...]

1116 5809

Open Access Short Communication

Narratives about Menopause

Received: 28 August 2023;  Published: 30 October 2023;  doi: 10.21926/obm.geriatr.2304256

Abstract

Narratives and how women interpret their symptoms have always been a part of how menopause is experienced. Today, as women feel more accessible to talk about menopause, new narratives are being formed and negotiated - both to menopause and concerning women becoming older. These different narratives mirror the fact that the transitional phase differs from woman to woman and that some women experience many symptoms while others do not seem bothered at all. Some narratives underscore menopause as a transformative peri [...]

2085 11493

Open Access Research Article

Sleep Quality, Sleep Efficiency, and Perceived Stress after Synchronous Virtual Mindfulness Meditation Sessions for Higher Education Students

Received: 09 August 2023;  Published: 30 October 2023;  doi: 10.21926/obm.icm.2304048

Abstract

This study examined the effects of virtual mindfulness meditation programming on sleep efficiency using wearable tracking devices, as well as effects on sleep quality and perceived stress in higher education students. A one-group, pretest-posttest design with convenience sampling and rolling recruitment over a six-month period resulted in twenty-five participants who completed the study and were included in data analysis. Paired t-tests were used to determine statistical significance for sleep efficiency measured u [...]

1462 9963

Open Access Original Research

Somaclonal Variation in Callus Cultures of Rose Periwinkle, Catharanthus Roseus L. Under Induced Salt and Osmotic Stresses

Received: 29 July 2023;  Published: 26 October 2023;  doi: 10.21926/obm.genet.2304200

Abstract

The experiment was carried out at the laboratories of the National Commission for Biotechnology in Syria during the period 2020-2022 to detect the somaclonal genetic variation occurring in callus cultures at different ages and to compare them with the In vitro growing plants and introduced species of Rose Periwinkle that grew up in the Syrian environment, in addition, exploring the effect of abiotic stresses in causing genetic variations in callus, by the Inter Simple Sequence Repeats technique (ISSR) using 21 prim [...]

1663 9666

Open Access Short Review

The Pathophysiology and Management of NAFDL in Post-menopausal Women: An Updated Short Review

Received: 10 May 2023;  Published: 26 October 2023;  doi: 10.21926/obm.geriatr.2304255

Abstract

Non Alcoholic Fatty Liver Disease (NAFDL) is a condition in which an individual suffers from an accumulation of fat in the liver. This is a disease condition with a multifactorial etiology. Some potent causes of such conditions are altered thyroid condition, abnormal metabolism in the body due to aging or menopause, or any other hormonal imbalance. Most of these causes are regulated by genetics, lifestyle, and environmental factors. Menopause comes with tremendous hormonal turmoil in the human body and brings vario [...]

1326 7937

Open Access Conference Report

Report from the 11th International Symposium on Auriculotherapy Held in Copenhagen, 8-10 September 2023 - Auriculotherapy meets the field of Psychology

Received: 25 October 2023;  Published: 26 October 2023;  doi: 10.21926/obm.icm.2304047

2137 12329

Open Access Original Research

Mesoscale Modeling of Extrusion and Solidification During Material Extrusion Additive Manufacturing

Received: 22 August 2023;  Published: 25 October 2023;  doi: 10.21926/rpm.2304033

Abstract

In this work, we apply a multiphysics approach to fused deposition modeling to simulate extrusion and solidification. Restricting the work to a single line scan, we focus on the application of polylactic acid. In addition to heat, momentum and mass transfer, the solid/liquid/vapor interface is simulated using a front-tracking, level-set method. The results focus on the evolving temperature, viscosity, and volume fraction and are cast within a set of parametric studies, to include the printing and extrusion speed, a [...]

1774 8652

Open Access Editorial

Welcoming the “Metaverse” in Integrative and Complementary Medicine: Introductory Overview

Received: 17 October 2023;  Published: 25 October 2023;  doi: 10.21926/obm.icm.2304046

Abstract

The digital transformation of healthcare is accelerating. At the forefront of this revolution is the development of the "metaverse." This multidimensional digital universe, where virtual and physical realities converge, is reshaping the potential of integrative and complementary medicine. In this special edition journal series, we explore how metaverse technologies such as virtual reality, augmented reality, avatars, digital twins, blockchain smart contracts, and more, are poised to revolutionize holistic healthcar [...]

1936 9144

Open Access Research Article

Alone within the ALONESS of Covid-19: Developing Contemplative, Artistic Inner Friendship for Turbulent Times

Received: 27 March 2023;  Published: 25 October 2023;  doi: 10.21926/obm.icm.2304045

Abstract

Art therapy, imaginal mindfulness, yoga, and meditation were personal and collegial necessities for surviving the emotional fallout of isolation during the Covid-19 pandemic. Combining these practices offered us credible resources for enhancing our social, cultural, and spiritual wellness when faced with the loneliness of lockdown living. This article applies an autoethnographic lens highlighting the value of these contemplative tools for managing pandemic related distress within myself and my professional peer gro [...]

1278 6764

Open Access Original Research

Examining the Relationship between Attitudes Towards Genomic Technology and Genetic Entrepreneurial Intention among Egyptian Healthcare Professionals

Received: 24 September 2023;  Published: 24 October 2023;  doi: 10.21926/obm.genet.2304199

Abstract

In the contemporary landscape, nurturing genomic entrepreneurial attitudes and intentions poses a substantial challenge for healthcare organizations. The present paper examines the factors affecting attitudes towards genomic technology and entrepreneurial intentions among Egyptian healthcare professionals. The study applied a quantitative approach and collected cross-sectional data from 276 health professionals using convenience sampling. Using structural equation modeling (SEM) through SmartPLS 4, the findings sug [...]

1205 6786

Open Access Original Research

The Exploration of the Experience of Expressive Therapies in a Pediatric Medical Setting in the COVID-19 Pandemic through Arts-Based Research

Received: 03 June 2023;  Published: 24 October 2023;  doi: 10.21926/obm.icm.2304044

Abstract

The COVID-19 pandemic presented a host of issues for hospitalized patients including increased anxiety, fear, isolation, and depression [1]. Expressive Therapies have been used in the pediatric medical setting for decades to support patients and families with coping, expression, processing, and rehabilitation [2,3,4,5]. Additionally, some studies suggest that Expressive Therapies were effective in helping ease the increase in mental health symptoms that occurred during the pandemic. During the pandemic the expressi [...]

1174 5958

Open Access Review

The Impact of Climate Change on Older Adults’ Mental Health: A Primer for Clinicians

Received: 31 July 2023;  Published: 24 October 2023;  doi: 10.21926/obm.geriatr.2304254

Abstract

Climate change is a major public health emergency. Natural disasters (earthquakes, floods, hurricanes, tornadoes, tsunamis, landslides, wildfires, and volcanic eruptions) have been increasing in frequency and severity and can cause lasting psychological sequelae. Older adults are highly vulnerable to the physical and mental health impacts of extreme weather and natural disasters. A narrative review was conducted to identify and summarize English-language articles focusing on the impact of climate change on older ad [...]

2770 18458

Open Access Review

Technological Resources for Early Intervention in Cases of Dyscalculia: A Deductive-Inductive Categorization

Received: 29 May 2023;  Published: 23 October 2023;  doi: 10.21926/obm.neurobiol.2304191

Abstract

Dyscalculia is a math learning disability that significantly interferes with students' academic performance and math-related aspects of their daily lives. Early diagnosis and the design of intervention programs adapted to the needs of each case are essential. In this sense, multiple technological resources are created to address both issues. Still, it is difficult to identify which characteristics they share and which are more relevant regarding didactic suitability. Given this situation, this research proposes cat [...]

2142 16612

Open Access Case Report

Using Hypnotic Techniques and Guided Imagery in Treatment of a Highly Hypnosible Woman with Slowly Progressing Chronic Organic Brain Disorder: A Case Study

Received: 25 May 2023;  Published: 20 October 2023;  doi: 10.21926/obm.icm.2304043

Abstract

A therapeutic intervention combines guided imagery and hypnotic techniques (including self-hypnosis), direct and indirect suggestions, medical treatments, and highly improving patient condition. A variety of hypnotic intervention techniques were introduced to treat a highly hypnotizable patient suffering from an advanced organic brain disorder due to an autoimmune disease and resistant to traditional medicine, showing no improvement despite being highly motivated and cooperating with conventional measures. Progress [...]

1710 8950

Open Access Review

Mutation Breeding in Horticultural Plant Species

Received: 27 July 2023;  Published: 19 October 2023;  doi: 10.21926/obm.genet.2304198

Abstract

In the face of rapid population growth worldwide, humanity's need for plant and animal products is increasing. In this regard, the organizations in charge of production make production and consumption forecasts for the future and try to accelerate the work aimed at increasing production. There are various ways of increasing production. The first of these is the improvement of cultivation techniques, the expansion of irrigated agricultural areas, and the effective control of diseases and pests. The second is to find [...]

1939 16165

Open Access Research Article

Factor Structure of ASD Symptoms in Russian 3-4-Year-Olds

Received: 08 June 2023;  Published: 19 October 2023;  doi: 10.21926/obm.neurobiol.2304190

Abstract

The study aims to reveal autism vectors that are inherent in 3-4-year-olds with ASD. Three hundred eighty-three children with ASD took part in the research. An online questionnaire developed earlier by our research group was used. In the first stage, with the repeated use of exploratory factor analysis, the task of identifying the simplest factor structure was solved. As a result, a 7-factor system was obtained, including from 9 to 14 items in each factor (78 items in total): 1) "Persistence on sameness" (Sam); 2) [...]

1660 8443

Open Access Review

Enhancement Techniques for the Reduction of Heating and Cooling Loads in Buildings: A Review

Received: 12 June 2023;  Published: 19 October 2023;  doi: 10.21926/jept.2304031

Abstract

The building sector is rated as a big consumer of electric energy and emissions, responsible for about 40% of final electric energy consumption. As a result, the Paris Agreement 2015 set a goal for buildings and the construction sector to reach a nearly zero-carbon stage by 2050. This urged most countries to create regulations for the construction sector and invest in energy efficiency programs. The present paper aims to present an updated review of building energy-saving solutions and techniques to contribute to c [...]

3181 21562

Open Access Review

Newborn Screening for Inborn Errors of Metabolism

Received: 14 June 2023;  Published: 18 October 2023;  doi: 10.21926/obm.genet.2304197

Abstract

Newborn screening can now detect more than 50 disorders, providing early and often life-saving treatment. Inborn errors of metabolism account for the majority of these disorders. This review will consider the more common metabolic disorders identified on newborn screening, including history, technique and management of these disorders.

1906 12812

Open Access Technical Note

A New Computer-Aided Method for Assessing Children's Cognition in Bioengineering Systems for Diagnosing Developmental Delay

Received: 05 April 2023;  Published: 18 October 2023;  doi: 10.21926/obm.neurobiol.2304189

Abstract

This pilot study (n = 19) examines fidelity rates of the new computer-aided method of diagnosing cognitive development delay in 3-to-6-year-old children. The small-scale research repeats the methodological components of the previous two studies, only changing the data collection process by introducing the baseline value (BV). Experimental data show a significant increase of 9.4 times in the shared intentionality magnitude in neurodivergent children. The results support the hypothesis that the bioengineering system [...]

1290 10281

Open Access Concept Paper

Nexus Between Heat and Air Pollution in Urban Areas and the Role of Resilience Planning in Mitigating These Threats

Received: 14 February 2023;  Published: 17 October 2023;  doi: 10.21926/aeer.2304047

Abstract

Urban heat island (UHI) effects are evident in many cities globally. Studies have revealed that UHI impacts air pollution and vice versa. However, it is observed that these two severe problems are addressed independently instead of interrelatedly. The study seeks to provide an in-depth understanding of the relationship between air pollution and heat and how they constantly shape urban areas for planning and future research purposes. A global shift from sustainable planning practices to building urban resilience exi [...]

1878 20706

Open Access Short Review

Utility of MEST and MEST-C Scoring in IgA Nephropathy in Kidney Transplantation: A Mini Review

Received: 26 June 2023;  Published: 13 October 2023;  doi: 10.21926/obm.transplant.2304199

Abstract

IgAN is a major cause of end-stage kidney disease (ESKD) leading to kidney transplantation in a significant proportion of patients. However, its recurrence in transplanted kidneys can lead to graft loss. The rate of graft loss attributable to IgAN after transplantation is variably reported in different retrospective cohorts. Previous reports describe recurrence rates of 22-58% with a 1.3% to 16% rate of graft loss. Accurate diagnosis and prediction of graft loss are important for planning effective therapies to imp [...]

1289 7946

Open Access Case Report

Neuroleptic Malignant Syndrome in a Patient with Autism Spectrum Disorder: Case Report

Received: 10 May 2023;  Published: 13 October 2023;  doi: 10.21926/obm.neurobiol.2304188

Abstract

Neuroleptic Malignant Syndrome (NMS) and Malignant Catatonia (MC) are conditions with significant overlap and are classically characterized by autonomic dysfunction, rigidity, bradyreflexia, posturing, lead-pipe rigidity in the former and waxy flexibility in the latter, stereotyping, an increase in creatinine kinase, and/or leukocytosis. Onset after inciting factor ranges from days to weeks, as does resolution with appropriate treatment. The overlap in symptomatology with Autism spectrum disorder (ASD) presents a f [...]

1429 10184

Open Access Original Research

Tungstophosphate Intercalated ZnAl Layered Double Hydroxide for Adsorptive and Visible Light Driven Photocatalytic Decolourisation of Organic Dyes

Received: 21 December 2022;  Published: 13 October 2023;  doi: 10.21926/cr.2304025

Abstract

Tungstophosphate (PW12O403-) intercalated ZnAl-Layered double hydroxide (ZnAl-PW12) was successfully synthesized through the rehydration of calcined LDH. Chemical analyses and characterizations by powder XRD, FT-IR, and Diffuse reflectance UV-Vis spectra confirmed the intercalation of PW12O403- ions equivalent to ~80% of the residual positive charge in the brucite layer. The efficiency of ZnAl-PW12 for decolourisation of four structurally different cationic/anionic dyes through simultaneous adsorption and photocata [...]

1588 9177

Open Access Review

Multimodal Pain Management of Liver Transplantation: What Is New?

Received: 14 May 2023;  Published: 13 October 2023;  doi: 10.21926/obm.transplant.2304198

Abstract

Liver transplantation (LT) is a life-saving treatment representing the only viable option for patients suffering from end-stage liver disease (ESLD) or acute liver failure. Patients who undergo LT require a multidisciplinary approach to postoperative pain management. However, pain management in this context is often inadequately explored. Limited options exist for proper pain control in patients with hepatic failure, mainly due to the increased risk of kidney and multi-organ failure. In LT candidates, specific anal [...]

2156 15500

Open Access Review

Coping with Burnout in the Healthcare Field

Received: 27 July 2023;  Published: 13 October 2023;  doi: 10.21926/obm.icm.2304042

Abstract

The healthcare industry is the largest and fastest growing industry in the world; however, being a part of the healthcare system involves being at an increased risk of experiencing mental health problems, loneliness, stress, and increased susceptibility to experiencing compassion fatigue related to the emotional wear associated with providing patient-centered care. Healthcare workers include, but are not limited, to physicians, nurses, allied health professionals, and psychologists. Often, healthcare workers place [...]

1938 9937

Open Access Short Review

Perovskite Oxide Thermoelectric Module - A Way Forward

Received: 27 July 2023;  Published: 11 October 2023;  doi: 10.21926/cr.2304024

Abstract

In the era of renewable and sustainable energy, perovskite materials remain pioneers as energy harvesting materials, be it thermoelectric waste heat harvesting or photovoltaic solar cell application. Oxide perovskite material is an emerging thermoelectric material in solving energy shortage issues through waste heat recovery. The chemical and structural stabilities, oxidation resistance, and cost-effective and straightforward manufacturing process are a few advantages of the oxide-based thermoelectric materials. Th [...]

2327 11813

Open Access Review

Lung Transplantation: Selection of Candidates

Received: 07 August 2023;  Published: 11 October 2023;  doi: 10.21926/obm.transplant.2304197

Abstract

Lung transplantation is a last-resort treatment option for patients with end stage lung disease. The procedure is being performed more frequently and scientific advances continue to be made, but the median post-transplant survival is far shorter than other solid organ transplant recipients. Candidate selection is a resource intensive process that attempts to balance risks of the procedure with the benefits of much higher quality of life. Transplant centers must weigh disease specific considerations, medical comorbi [...]

4712 21690

Open Access Original Research

‘It’s Nice for My Body but I Don’t Like It’ – Experiences of Soothing Rhythm Breathing in Clients with Depression

Received: 25 August 2023;  Published: 11 October 2023;  doi: 10.21926/obm.icm.2304041

Abstract

Soothing-rhythm breathing (SRB) is a core component of compassion focused therapy (CFT). While integral to CFT, research has yet to explore personal experiences of SRB. This study aimed to explore the experiences of individuals with depression who had practiced SRB in NHS primary care services. Interpretative phenomenological analysis (IPA) was used to analyse data from individual semi-structured interviews. Three experiential themes were identified: ‘mind-body connection and bodily needs’, ‘a new relationship with [...]

1718 11925

Open Access Short Review

Age-Related Pathologies and Life Span

Received: 27 July 2023;  Published: 11 October 2023;  doi: 10.21926/obm.geriatr.2304253

Abstract

Both from a healthcare and a socioeconomic perspective, research on senescence is increasingly essential. Indeed, in industrialized countries, the increased human longevity confronts medicine with many old patients with age-related pathologies. The paper reviews the biological theories on aging, the impact of reactive oxygen species, telomers, epigenetics, and genetics (e.g., gerontogenes) on-age-related pathologies. Also, the paper reviews available and under research therapeutic approaches (e.g., senolytics) aime [...]

1230 7256

Open Access Short Communication

Rethinking Driving Assessment: A Hypothesis-Driven Proposal for Cognitive Evaluation

Received: 31 March 2023;  Published: 10 October 2023;  doi: 10.21926/obm.neurobiol.2304187

Abstract

Driving is a critical aspect of personal mobility and autonomy, but ensuring road safety requires a comprehensive evaluation of driving abilities beyond self-reported behaviors and practical skills. This article emphasizes the importance of cognitive assessment in determining fitness to drive and explores the potential benefits of using digital tools for such evaluations to enhance road safety. Implementing these digital tools does come with challenges, such as unfamiliarity with digital cognitive reviews for some [...]

1697 9994

Open Access Review

Role of Metabolic Nutrition in Newborn Screening and Inherited Metabolic Disorders

Received: 29 June 2023;  Published: 10 October 2023;  doi: 10.21926/obm.genet.2304196

Abstract

The expansion of newborn screening (NBS) encompasses a wide range of inherited metabolic disorders, including disorders of carbohydrate, lipid, and protein metabolism. Effective treatment of these disorders requires comprehensive nutrition and medical management. This review highlights the intricacies of medical nutrition therapy for several common metabolic disorders and underscores the crucial role of metabolic dietitians in managing these patients.

1285 10713

Open Access Original Research

Evaluation of Bioactive Compounds Obtained from Ginkgo Biloba Against Crystal Structure of Myelin Oligodendrocyte Glycoprotein (MOG)

Received: 07 July 2023;  Published: 09 October 2023;  doi: 10.21926/obm.neurobiol.2304186

Abstract

Multiple Sclerosis (MS) spreads rapidly across the globe, causing almost 2.8 million cases worldwide. Many drugs and inhibitors, such as dronabinol and nabilone, have been used to treat MS, but there is no effective treatment for MS till now as these medications can cause severe side effects. So, we tested different compounds from Ginkgo biloba to inhibit the symptoms caused by MS as an herbal treatment. We targeted the Crystal structure of Myelin Oligodendrocyte Glycoprotein as it has shown some excellent results [...]

1445 9183

Open Access Original Research

Maximizing the Benefit of Respite for Dementia Caregivers: A Study Protocol Describing the Development & Evaluation of the Time for Living & Caring (TLC) Intervention

Received: 15 June 2023;  Published: 08 October 2023;  doi: 10.21926/obm.icm.2304040

Abstract

Dementia caregivers are susceptible to adverse physical and mental health outcomes, given the often prolonged and challenging care and support they provide to family members with Alzheimer’s Disease and Related Dementias (ADRD). This report describes a community-engaged implementation of a novel behavioral intervention - an “app” (interactive website) called TLC (Time for Living and Caring) that coaches caregivers on how to maximize the benefits associated with respite time. The rationale and features of the TLC in [...]

1885 9347

Open Access Review

Whole Genome Sequencing in Era of Newborn Screening

Received: 20 April 2023;  Published: 05 October 2023;  doi: 10.21926/obm.genet.2304195

Abstract

After the completion of the human genome project, there have been many advances in the field of genetics. With next generation sequencing, patients can undergo genomic analysis through whole exome or whole genome testing. These comprehensive tests can shorten the diagnostic odyssey and guide medical management and thereby potentially reduce mortality and morbidity. To date, parents and physicians have reported positive perceptions of using these genomic testing even when a diagnosis is not made. Remaining challenge [...]

1537 10905

Open Access Review

Screening and Treating Urinary Incontinence in Primary Care: A Missed Opportunity

Received: 12 May 2023;  Published: 05 October 2023;  doi: 10.21926/obm.geriatr.2304252

Abstract

More than 60% of adult women in the United States have urinary incontinence (UI), with the prevalence increasing to over 80% in women over age 65. Despite its high prevalence, most patients do not seek care and few clinicians screen for UI. The Medicare Health Outcomes Survey queries patients about satisfaction with their provider’s discussion and management of UI, but formal recommendations about screening, diagnosis, and treatment are lacking. This review presents a practical algorithm for primary care providers [...]

2065 11562

Open Access Review

Mixed Urinary Incontinence: Diagnosis and Management

Received: 17 May 2023;  Published: 05 October 2023;  doi: 10.21926/obm.geriatr.2304251

Abstract

The evaluation and treatment of mixed urinary incontinence receives relatively little attention as compared to other forms of incontinence. Mixed incontinence, however, defined as the combination of stress and urgency incontinence, accounts for the largest proportion of incontinence, with an increased incidence in older women. The condition can be very challenging to manage due to the coexistence of multiple pathologies. Treating either component can worsen the other, which means careful discussion of the risks and [...]

1591 13707

Open Access Short Communication

Shared Intentionality Modulation at the Cell Level: Low-Frequency Oscillations for Temporal Coordination in Bioengineering Systems

Received: 20 June 2023;  Published: 05 October 2023;  doi: 10.21926/obm.neurobiol.2304185

Abstract

The theoretical article aims to develop knowledge about the modulation of shared intentionality at the cellular level. A hypothesis about the neurobiological processes during shared intentionality argues that this pre-perceptual communication occurs through nonlocal neuronal coupling in an ecosystem that can be described as the mother-fetus communication model. The current theoretical study analyses literature to discuss recent findings on the effect of oscillations on neuronal temporal coordination to verify wheth [...]

1747 32930

Open Access Original Research

Recycling Spent Coffee Grounds on Permeable Interlocking Concrete Paving Blocks

Received: 14 August 2023;  Published: 03 October 2023;  doi: 10.21926/aeer.2304046

Abstract

Decomposition of spent coffee grounds (SCGs), a byproduct of brewing coffee, in disposed landfill sites releases significant amounts of potent greenhouse gases. This study aims to investigate the maximum recycling proportions of SCGs, a nonconventional filler material, for permeable interlocking concrete paving (PICP) blocks. These blocks have a porous structure that helps mitigate surface ponding while maintaining sound structural performance. Using Scanning Electron Microscope image analysis, the water absorbency [...]

1689 12152

Open Access Original Research

Generalized Normal Distribution Optimization Algorithm for Economic Dispatch with Renewable Resources Integration

Received: 18 June 2023;  Published: 28 September 2023;  doi: 10.21926/jept.2303030

Abstract

In an electric power system operation, the main goal of economic dispatch (ED) is to schedule the power outputs of committed generating units efficiently. This involves consideration of relevant system equality and inequality constraints to meet the required power demand at the lowest possible operational cost. This is a challenging optimization problem for power system operators that can be dealt with efficient meta-heuristic algorithms. This article uses a recent meta-heuristic approach named the generalized norm [...]

1476 9868

Open Access Original Research

Nature and City Sounds Influence Physiological and Psychological Markers in College Students

Received: 02 March 2023;  Published: 28 September 2023;  doi: 10.21926/obm.icm.2303039

Abstract

Worldwide, human population growth has led to a higher demand for urbanization. While this development is in accordance with our gregarious lifestyles, our availability and contact with nature has consequentially been minimized. The goal of this study was to evaluate whether sounds from nature versus urban environments affect vital signs (i.e., heart rate and respiration rate) and mood states of female college students. Emotional states were assessed using the Positive and Negative Affect Schedule (PANAS) questionn [...]

1594 8591

Open Access Short Review

Effects of Natural Substances on Lowering Uric Acid

Received: 03 March 2023;  Published: 28 September 2023;  doi: 10.21926/rpn.2303019

Abstract

Uric acid (UA) metabolism, which includes uric acid production controlled by purine metabolism and uric acid excretion controlled by the gastrointestinal tract and kidneys, is the primary way to maintain the concentration of uric acid in the body. Abnormal functionalizing of the metabolism may cause hyperuricemia, gout, kidney injury, and other diseases. Over the last decade, numerous studies have been conducted on the effect of natural products, including active ingredients of medicinal plants, natural compounds, [...]

4753 20395

Open Access Original Research

A Urinary Proteomics Approach to Predict Treatment Response in Acute Antibody-Mediated Rejection

Received: 12 July 2023;  Published: 25 September 2023;  doi: 10.21926/obm.transplant.2303196

Abstract

Acute antibody-mediated rejection (AMR) is a severe complication affecting kidney allografts' long-term survival. Timely detection and appropriate treatment of AMR are crucial for improving graft outcomes. This study aimed to discover non-invasive urinary biomarkers that can predict the response to therapy in patients with AMR. Materials and Methods: In this case-control study, urine samples from 21 biopsy-proven AMR patients underwent proteomics using label-free quantification. The patients were divided into two g [...]

1193 6710

Open Access Review

Overview of Newborn Screening of Lysosomal Storage Diseases for Pediatric Care Providers

Received: 14 June 2023;  Published: 25 September 2023;  doi: 10.21926/obm.genet.2303194

Abstract

Lysosomal storage disorders (LSD) are caused by enzymatic failure to degrade specific cellular byproducts of metabolism within the lysosome. They have a wide range of presentations involving multiple body systems and can manifest from infancy through adulthood. As treatments have become available for many of these disorders, newborn screening has been adapted for early identification and pre-symptomatic treatment. This article will review some of the LSD that are now being added to newborn screening panels, includi [...]

1301 11358

Open Access Research Article

Demographic Factors, COVID-19-related Factors, and PTSD Symptom Clusters: Exploring Associations and Implications for Mental Health

Received: 26 April 2023;  Published: 25 September 2023;  doi: 10.21926/obm.neurobiol.2303184

Abstract

The COVID-19 pandemic was characterized as a continuous traumatic stressor and associated with high levels of posttraumatic stress disorder (PTSD). This study examines the associations between demographic factors, COVID-19-related factors (fear of COVID-19 and perceived stress), and PTSD, as well as the associations between PTSD and indices of mental health. The participants in the study were university students (n = 322) who completed the PTSD Checklist for the Diagnostic and Statistical Manual-5 (DSM-5), the Fear [...]

1114 6031

Open Access Editorial

Nb2O5: Percentage Effect of T/H Phase and Evaluation of Catalytic Activity, a Preliminary Study

Received: 18 September 2023;  Published: 22 September 2023;  doi: 10.21926/cr.2303023

Abstract

Due to its similar characteristics to titanium, niobium has become an attractive alternative in photocatalytic processes. Research indicates that titania has an optimal percentage of phases resulting in a commercial catalyst, P25, that contains more than 70% anatase with a minor amount of rutile and a small amount of amorphous phase. On the other hand, for Nb2O5, percentage optimization was little explored in the literature, which consists of studying the phases obtained via heat treatment individually and in diffe [...]

1760 8601

Open Access Research Article

Arginine and Histidine-modified Layered Double Hydroxides Facilitate Transgene Expression in Cancer Cells in Vitro

Received: 14 June 2023;  Published: 21 September 2023;  doi: 10.21926/obm.genet.2303193

Abstract

Layered double hydroxides (LDHs) have interesting properties and structures that enable them to carry nucleic acids, such as deoxyribonucleic acid (DNA). This study synthesized LDHs using the co-precipitation method and functionalized with the amino acids arginine (Arg) and histidine (His) to promote proton-sponge activity for enhanced transgene expression. The LDHs were characterized using X-ray diffraction (XRD), transmission electron microscopy (TEM), and nanoparticle tracking analysis (NTA). The interaction of [...]

1691 7564

Open Access Review

Heart Failure in Elderly People: From Pathophysiology to Diagnosis and Management

Received: 05 March 2023;  Published: 19 September 2023;  doi: 10.21926/obm.geriatr.2303250

Abstract

As the older population increases, there is an increase in age-related chronic diseases, especially heart failure. It affects 25% of over 75-year-old outpatients and represents the leading cause of hospitalization and death in older people. This review aimed to point out the main characteristics concerning heart failure in older people, taking into account clinical symptoms, diagnosis, and treatment. An extensive search on heart failure was made on PubMed and Google, using the keywords older people, heart failure, [...]

1653 14547

Open Access Original Research

Barley and Malt as Base Ingredients for the Production of New Bio-Functional Foods

Received: 14 April 2023;  Published: 19 September 2023;  doi: 10.21926/rpn.2303018

Abstract

This work aimed to evaluate the chemical composition, bioactive compounds (phenolics and γ-aminobutyric acid, GABA), and antioxidant properties of different barley varieties (Overture, Charles, Sinfonía, Montoya, and Andreia) and their malts to weigh up them as potential ingredients for producing new bio-functional foods. For this, five barleys and five malts obtained from them were studied. Regarding chemical composition, total starch was the main component (≈62%) of barleys followed by total di [...]

1827 12303

Open Access Short Review

Normal and Aberrant Muscle Tissue Healing, Learning from Health and Disease

Received: 28 March 2023;  Published: 19 September 2023;  doi: 10.21926/obm.genet.2303192

Abstract

Human skeletal muscle exhibits remarkable plasticity, being responsive to chemical, mechanical, metabolic, and inflammatory stress. When the homeostatic disturbance is below a threshold of significant damage, the muscle responds by modifying metabolic activity, cell size/shape, and structure, thereby normalizing cellular function. If the disturbance causes significant damage, skeletal muscle, along with a precisely choreographed response from the immune system, can regenerate. Very few pathological conditions inhib [...]

1198 7888

Open Access Original Research

Resilience and Burnout among Medical Students: The Role of Difficulties with Emotion Regulation as A Mediator

Received: 06 March 2023;  Published: 19 September 2023;  doi: 10.21926/obm.icm.2303038

Abstract

Burnout is a chronic state of exhaustion caused by prolonged stress. Medical training has been shown to leave many medical students vulnerable to burnout, which can negatively impact their health and patient care. While resilience has been associated with lower burnout, the mechanisms through which resilience reduces burnout are not well established. Therefore, this study aimed to investigate whether difficulties with emotion regulation mediate the relationship between resilience and burnout among medical students. [...]

1651 9767

Open Access Original Research

Bringing the Inside Out and the Outside in: The Therapeutic Relationship in Compassion Focused Therapy Chairwork

Received: 01 July 2023;  Published: 19 September 2023;  doi: 10.21926/obm.icm.2303037

Abstract

Chairwork is a central component in Compassion Focused Therapy (CFT). Despite its importance, there has been no prior research on the relational factors underpinning the application of chairwork in CFT. There is also a general paucity of research on the role of the therapeutic relationship in chairwork across modalities. This paper analyses data from interviews with 21 clients following a CFT chairwork intervention to ascertain how relational factors influenced their experience of this method. An Interpretative Phe [...]

1537 11955

Open Access Short Communication

Redefining Hypotension in Older Adults: Implications for the Prevention of Age Related Cognitive Decline

Received: 24 April 2023;  Published: 18 September 2023;  doi: 10.21926/obm.geriatr.2303249

Abstract

Chronically low blood pressure in older adults is associated with significantly increased long-term risks of dementia and all-cause mortality risk. Yet low blood pressure is generally not treated until an individual begins to experience the acute symptoms arising from very low cerebral perfusion. However, these acute symptoms, such as dizziness, balance difficulty, syncope, increased fall occurrence, vision impairment, and nausea, begin to occur only at very low blood pressure levels, such that mean arterial pressu [...]

1349 12321

Open Access Original Research

A Comparative Study of R134a and Propane (R290) as Refrigerants in Heat Pump Water Heaters

Received: 26 March 2023;  Published: 18 September 2023;  doi: 10.21926/jept.2303029

Abstract

In the context of decarbonization efforts, heat pump water heaters (HPWHs) offer an attractive solution over conventional electric resistance type hot water systems due to their 2-3 times higher efficiency. However, the high manufacturing costs and taxes associated with using hydrofluorocarbon (HFC) refrigerant make HPWHs expensive. As a means to tackle this issue, this paper explores the use of propane (R290) as a refrigerant in HPWHs. The study involves an experimental comparison of R290 and R134a, with refrigera [...]

3679 49834

Open Access Research Article

How COVID-19 Ceases All Older Adult Services & the Way Out for Community-Dwelling Older Adults with Chronic Pain

Received: 02 August 2023;  Published: 15 September 2023;  doi: 10.21926/obm.neurobiol.2303183

Abstract

The COVID-19 pandemic started at the beginning of 2020. It significantly impacted the older adults in Hong Kong, with most of the community centers and elderly centers being closed down under various restrictive measures. Thus, community-based health promotion activities were temporarily paused, which decreased older adults’ health-promoting behaviors and motivation to stay active. This research aimed to improve the quality of life and the health of older adults with chronic pain through the pain management program [...]

1259 7004

Open Access Review

Inclusion of Dietary-Fibers in Nutrition Provides Prebiotic Substrates to Probiotics for the Synthesis of Beneficial Metabolites SCFA to Sustain Gut Health Minimizing Risk of IBS, IBD, CRC

Received: 19 July 2023;  Published: 14 September 2023;  doi: 10.21926/rpn.2303017

Abstract

Usually, everyday meals constitute materials and ingredients for food preparation derived from different agricultural sources. Although most customers are aware of the benefits of a balanced diet, they mainly focus on a diet based on the daily requirements of protein, fat, and carbohydrates in their meals. However, the vital aspect of the including dietary fibers in diets is overlooked, which is equally important as is the daily requirement of calories and protein intake for maintaining the muscle mass. Some societ [...]

1780 12318

Open Access Original Research

Overall Reaction Rate Study of Thermal Methane Cracking in Non-Isothermal Conditions

Received: 10 April 2023;  Published: 13 September 2023;  doi: 10.21926/jept.2303028

Abstract

The thermal cracking of methane (TMC) is a significant reaction occurring above 850°C, which proceeds in two stages: non-isothermally and isothermally. However, most existing studies have focused on obtaining reaction rates under isothermal conditions [1], limiting their applicability to practical industrial reactor conditions. This novel research aims to determine the overall thermal decomposition rate of methane to hydrogen and carbon in adiabatic conditions, covering the range of unstable industrial reactor temp [...]

1916 8447

Open Access Editorial

Treatments and Management of Menopausal Symptoms: Current Status and Future Challenges

Received: 31 August 2023;  Published: 13 September 2023;  doi: 10.21926/obm.geriatr.2303248

Abstract

In the United States (US), menopause occurs at an average age of 52. Menopausal symptoms tend to be maximal during the few years before and the year after menopause (during perimenopause), except for symptomatic vulvovaginal atrophy, which may worsen over time. Up to 20% of bone density loss occurs during the first 5 years after menopause, followed by an age-related bone loss rate similar to that in men. Menopause should be considered confirmed if an age-appropriate woman who is not pregnant has not had a menstrual [...]

4951 27692

Open Access Research Article

Chair Fitness Program for Improved Strength and Physical Function for Older Adults: A Pilot Comparative Effectiveness Study

Received: 05 July 2023;  Published: 12 September 2023;  doi: 10.21926/rpn.2303016

Abstract

Within the US, people are experiencing longer life expectancy, yet these extended lifespans have not necessarily translated into years living in good health. Musculoskeletal degenerative diseases are particularly prevalent amongst older adults. Research shows that regular resistance exercise carries preventive health benefits to combat these conditions. This study evaluated the impact of an innovative hand-held device (OYO) on the physical function of older adults compared to a traditional chair fitness program (CF [...]

1718 16528

Open Access Original Research

Enhancing Kerosene Selectivity of Fischer-Tropsch Synthesis by Periodical Pore Drainage Via Hydrogenolysis

Received: 27 June 2023;  Published: 12 September 2023;  doi: 10.21926/cr.2303022

Abstract

Accumulation of wax inside the catalyst pores during transient cobalt-catalyzed Fischer-Tropsch synthesis (FTS) leads to unfavorable product distribution and low activity by imposing internal mass transfer limitations. The condensation of paraffin severely changes the apparent product stream that actually leaves the reactor before the catalyst pores are filled completely and the steady state is reached. Thus, the product distribution of the transient FTS is less complex than expected in comparison to the steady-sta [...]

2163 14646

Open Access Research Article

Oral Versus Intravenous Anti-CMV Preemptive Strategies in Allogeneic Stem Cell Transplant Patients with CMV Reactivation: Experience from the National Center of Bone Marrow Transplantation, Tunis, Tunisia

Received: 12 April 2023;  Published: 12 September 2023;  doi: 10.21926/obm.transplant.2303195

Abstract

Cytomegalovirus (CMV) infection is a common and severe complication following allogeneic stem cell transplantation (ASCT) and requires effective preemptive antiviral therapy. Both oral and intravenous (IV) antiviral agents effectively reduce CMV viral load and achieve viral clearance. Studies comparing oral and IV anti-CMV preemptive treatment in ASCT patients with CMV reactivation showed a potential difference in treatment response and safety profiles between the two administration routes. We retrospectively compa [...]

1091 7258

Open Access Original Research

Exploring the Potential of Phase Change Material for Thermal Energy Storage in Building Envelopes

Received: 16 June 2023;  Published: 08 September 2023;  doi: 10.21926/jept.2303027

Abstract

Buildings, with their significant energy consumption, pose a pressing concern for the future. Inadequate heating, ventilation, and air-conditioning (HVAC) systems further exacerbate thermal management difficulties and energy requirements. To address these challenges, Phase Change Materials (PCMs) offer valuable potential for sustainable energy reduction within the building sector, leveraging passive cooling and heating techniques. Numerical study has been conducted to explore the impact of embedding PCM within the [...]

1474 12494

Open Access Original Research

Affinity for Technology Relates to Group Cohesion for New, But Not Existing, Groups

Received: 14 April 2023;  Published: 07 September 2023;  doi: 10.21926/obm.neurobiol.2303182

Abstract

During the 2020 COVID-19 pandemic, governments around the world mandated shutdowns and social distancing, limiting how much people could see other people outside of their household. Because of this, people had negative mental health outcomes, and many people turned to technology to maintain connections and create new ones. In this paper, we examine the relationship between technology, mental health, and group cohesion with existing groups (N = 202) and new groups (N = 74). We surveyed U.S. participants in June 2020 [...]

1272 7369

Open Access Research Article

Introducing a Novel Intervention, CoHealing, to Address Teacher Burnout and Indirect Trauma

Received: 28 February 2023;  Published: 07 September 2023;  doi: 10.21926/obm.icm.2303036

Abstract

The COVID-19 pandemic exacerbated the long-standing issues of stress and burnout in the education sector, with teachers and education staff facing unprecedented challenges including significant adjustments to teaching methods and balancing the mental health and academic needs of their students. The resulting challenges have contributed to heightened levels of stress and burnout among teachers and education staff. The impact of the pandemic on teachers and education staff has highlighted the need for greater support [...]

1465 9480

Open Access Research Article

Cultural Biases and Psychedelic Experiences: Western Scientific Perspectives about Amazonian Mestizo Therapeutic Traditions

Received: 02 April 2023;  Published: 07 September 2023;  doi: 10.21926/obm.icm.2303035

Abstract

This article aims to analyze how Western researchers can be influenced by their epistemic and ethical foundations, which are also expressed through a culturally shared idea of therapy, and how this influence can significantly hinder the understanding of a different cultural reality and its resources in terms of knowledge and practices. While examining a collection of research cases in the field of psychedelic therapy, the present paper focuses on the obstacles created by ethical and epistemic conflicts in the mind [...]

1500 15342

Open Access Case Report

A Rare and Complex Case of Multifactorial Thrombotic Microangiopathy in A Kidney Transplant Recipient: Interplay Between Antibody Mediated Rejection, Tacrolimus Toxicity, Cytomegalovirus Disease and BNT162b2mRNA Vaccine

Received: 11 May 2023;  Published: 04 September 2023;  doi: 10.21926/obm.transplant.2303194

Abstract

Thrombotic microangiopathy (TMA) in kidney transplant recipients is uncommon and difficult to manage, often with poor graft outcomes [1]. This is a complex and interesting case of an older, highly sensitised kidney transplant recipient who presented with de novo post-transplant TMA in the setting of antibody mediated rejection (ABMR), with other drivers being tacrolimus toxicity, cytomegalovirus (CMV) infection and anti-SARS-CoV-2 BNT162b2 mRNA vaccination. This led to rapid, irrecoverable graft loss. 76-year-old f [...]

1180 7049

Open Access Original Research

Pyrethrin Type Compounds from the Municipal Solid Waste Ghazipur Landfill Inert Soil as Brain and Cancer 5-HT Receptor Binding Agents

Received: 17 June 2023;  Published: 01 September 2023;  doi: 10.21926/rpm.2303032

Abstract

The Inert soil obtained from the Ghazipur Municipal Solid Waste landfill located in East Delhi, India has been used as the starting material for the work described in this paper. This mountain-like monster is often in the news for its bad smell, pollution of the groundwater in the area from its leachates, and the occasional fires in it endangering the lives of the people living nearby. Landfills produce many greenhouse gases (CO2, CH4, CO, HCHO, H2S, and NH3) which are poisonous and cause environmental pollution in [...]

1381 8079

Open Access Review

Secondary Findings of Newborn Screening

Received: 16 April 2023;  Published: 31 August 2023;  doi: 10.21926/obm.genet.2303191

Abstract

The aim of newborn screening (NBS) program is to detect and manage treatable conditions in the early stages prior to the occurrence of long-term and irreversible sequalae. Phenylketonuria was the first screened disorder, but panels rapidly expanded after the introduction of tandem mass spectrometry technology into the program. Significant differences in the diseases screened by NBS were noted between programs in United States. Therefore, the recommended uniform screening panel was developed in 2006 to include a lis [...]

1616 8577

Open Access Original Research

“Look, It’s a Dengue Mosquito”: A Qualitative Study on Living Near Open-Air Dumpsites and Vector-Borne Diseases

Received: 11 May 2023;  Published: 30 August 2023;  doi: 10.21926/aeer.2303045

Abstract

Currently, almost half of the human population is at risk of acquiring dengue. Other emerging pathogens affecting human populations transmitted by Aedes (Stegomyia) aegypti are chikungunya and Zika viruses. People who live in poor areas are more susceptible to be infected by these diseases. The lack of selective garbage collection and inadequate water storage are important factors in the dynamics of vector-borne transmission. This study took place in Estrutural City, the poorest city in Brasilia, Brazil, which host [...]

1773 13487

Open Access Original Research

Promoting College Student and Staff Well-being Through a Mindfulness-based Coping Program

Received: 23 February 2023;  Published: 30 August 2023;  doi: 10.21926/obm.icm.2303034

Abstract

This study evaluated the impact on student and staff well-being of a mindfulness-based cognitive-behavioral coping program, Be REAL (Resilient Attitudes & Living), delivered by campus staff using a task-sharing approach. The program was adapted for online delivery during COVID19. Study participants included 325 undergraduate students and 100 staff members at a large tri-campus university in the U.S. Participants completed surveys with self-report measures assessing mindfulness, perceptions of stress, emotion regula [...]

1806 12471

Open Access Original Research

Physicochemical Characterization and Mineral Composition of “UENF SD 08”: A Super-Sweet Corn Hybrid

Received: 30 December 2022;  Published: 27 August 2023;  doi: 10.21926/rpn.2303015

Abstract

Sweet Corn (Zea mays L.) is possibly the most important commercial cereal originating in the Americas. Mutant genes are responsible for sweetness. The purpose of this study was to evaluate the physicochemical and mineral composition of the “UENF SD 08” cultivar, super-sweet corn developed at Darcy Ribeiro Northern Rio de Janeiro State University (UENF) and registered in the National Cultivar Register of the Ministry of Agriculture, Livestock, and Supply and to compare its content to commercial super-swe [...]

1595 9431

Open Access Review

Classical and Non-Classical Neural Communications

Received: 13 April 2023;  Published: 27 August 2023;  doi: 10.21926/obm.neurobiol.2303181

Abstract

This review was constructed to show how the connectome has evolved in motor command systems from simple command elements to complex systems of neurons utilizing parallel distributed processing and the possibility of quantum entanglement between groups of neurons. Scientific and medical interest in neural pathways and their connections have driven neuroscience and brain research for many decades so that specific systems and their feedback loops have been considered in detail. We review motor command systems in inver [...]

1436 8358

Open Access Opinion

Life-Changing Bubbles: A Simple Solution That May Help Many

Received: 20 February 2023;  Published: 24 August 2023;  doi: 10.21926/obm.geriatr.2303247

Abstract

As the medical world continues to search for ways of improving the swallowing of many millions of Dysphagia sufferers around the world, this paper is devoted to presenting the case for carbonated water to be considered as a potential solution for many. The effectiveness of carbonated water (CW) in the rehabilitation of Dysphagia has been studied periodically over the last thirty years and some significant positive results have been recorded – but it is now proposed that further research should be directed to examin [...]

1138 7477

Open Access Original Research

Analysis of Interpersonal Relationships of Social Network Users Using Explainable Artificial Intelligence Methods

Received: 27 April 2023;  Published: 24 August 2023;  doi: 10.21926/obm.neurobiol.2303180

Abstract

The emergence of the social networking phenomenon and the sudden spread of the coronavirus pandemic (COVID-19) around the world have significantly affected the transformation of the system of interpersonal relations, partly shifting them towards virtual reality. Online social networks have greatly expanded the boundaries of human interpersonal interaction and initiated processes of integration of different cultures. As a result, research into the possibilities of predicting human behavior through the characteristic [...]

1656 11355

Open Access Original Research

COVID-19 Milieu and Its Psychological Effects on the Environmental Performance

Received: 03 June 2023;  Published: 22 August 2023;  doi: 10.21926/obm.neurobiol.2303179

Abstract

COVID-19 brought significant challenges that have ruined almost all segments of the economy and the environment. The present paper explores the COVID-19 milieu and its impacts the environmental performance (EP). We targeted managers of the Small and Medium-sized enterprises (SMEs) of Saudi Arabia to get online responses. Using the path analysis, the findings reveal a significant negative effect of the factors such as perception of COVID-19 (PoCVD), innovation capability (IC), environmental concern (EC) and the fear [...]

859 5405

Open Access Original Research

Impact of Feeding Time and Duration on Body Mass and Composition in Young, Exercising Mice

Received: 21 December 2022;  Published: 22 August 2023;  doi: 10.21926/rpn.2303014

Abstract

Time-restricted feeding (TRF) has increased in popularity among various groups, including fitness enthusiasts. The ideal timing of TRF in relation to daily exercise is unknown. Most fitness enthusiasts consume meals immediately or soon after exercise to improve body composition (e.g., lean mass). We compared two different TRF approaches, as well as an ad libitum control diet, with regards to body mass and body composition in C57BL/6 mice. Young, healthy, male mice exercised five days per week and were assigned to c [...]

1160 6977

Open Access Research Article

Bioactive Properties of Sorghum-based Beverages from Whole or Refined Grains

Received: 08 May 2023;  Published: 22 August 2023;  doi: 10.21926/rpn.2303013

Abstract

Sorghum-based beverages were developed and the effects of decortication on nutritional composition and biofunctional properties after a simulated gastrointestinal digestion were analyzed. For that, white sorghum flours from whole (WS) and decorticated (DS) grains were obtained and used to prepare sorghum beverages. They were analyzed regarding chemical composition, minerals, and phenolic acid contents. Moreover, the bioaccessibility of phenolics, proteins, and the potential bioactivity (ABTS+ scavenging, ACE-I inhi [...]

1518 9343

Open Access Short Communication

US State Hospital Regulations Rarely Include Malnutrition but Could Provide a Future Policy Framework for Improving Malnutrition Quality of Care

Received: 31 March 2023;  Published: 17 August 2023;  doi: 10.21926/obm.geriatr.2303246

Abstract

Malnutrition is a problem that is often not identified in hospitals as 8% of hospital patients are diagnosed but malnutrition is estimated to affect 20-50% of patients. Federal programs such as Joint Commission accreditation and the new, optional, global malnutrition composite score from CMS may improve inpatient malnutrition diagnosis, but there may be an opportunity to do more from a regulatory side. It’s unknown how many states are considering malnutrition from this standpoint. The study’s goal was t [...]

1198 9168

Open Access Review

Review on Material Performance of Carbon Nanotube-Modified Polymeric Nanocomposites

Received: 21 March 2023;  Published: 16 August 2023;  doi: 10.21926/rpm.2303031

Abstract

The chemically functionalized carbon nanotubes (f-CNTs) and hydrogen bonding modified polymer composites (CPCs) exhibit unique chemical, mechanical, electrical, and thermal properties and are emerging as promising materials to achieve extraordinarily high electrical and thermal conductivity, lightweight and anticorrosion, superior strength and stiffness for potential applications in the aerospace and automotive industries, energy conversion, and optical and electronic devices, therefore, attracting considerable res [...]

2761 18052

Open Access Original Research

Calculation Method of the Carbon Footprint of Products of Animal Origin Integrated with the Physiological Absorption of Carbon Dioxide: Calculation Example of the CFP of Mozzarella di Bufala Campana DPO

Received: 03 March 2023;  Published: 15 August 2023;  doi: 10.21926/aeer.2303044

Abstract

The environmental impact of emissions appears to be increasingly important for food, particularly those of animal origin. The LCA (Life-Cycle Assessment) method, an internationally standardized method used to calculate the environmental impact of goods or services, in the carbon footprint, does not take into account the carbon set and consequently the subtraction of carbon dioxide by the plant biomass whether or not aimed at the production of food of animal origin. This methodology could overestimate the carbon dio [...]

1368 87760

Open Access Research Article

Comprehensive Geriatric Assessment of Elderly Adults

Received: 23 March 2023;  Published: 14 August 2023;  doi: 10.21926/obm.geriatr.2303245

Abstract

The geriatric population is increasing all over the world. Aging people have special health requirements and comprehensive medical checkups prevent physical, functional and mental decline during the aging period. This study aimed to examine the fitness level and identify problems with the well-being of elderly persons. In this context, the study also attempted to determine the relationship between socio-demographic factors and the health status of elderly adults. In this cross-sectional study, 168 elderly adults (≥ [...]

1563 7944

Open Access Original Research

Burnout Among Special Education Teachers and the Role of Individual, Interpersonal, and Organizational Risk and Protective Factors

Received: 30 March 2023;  Published: 10 August 2023;  doi: 10.21926/obm.icm.2303033

Abstract

Burnout is a syndrome commonly characterized by the three dimensions of Maslach and Leiter's model, namely emotional exhaustion, depersonalization, and lack of professional accomplishment. While burnout affects individuals in all professions, teachers are recognized as being at particular risk, a fact explained in the literature by the high level of relational demands inherent to the profession. During the pandemic and subsequently, these demands have even increased. Several studies have focused on the influence of [...]

1693 11619

Open Access Original Research

“Welcome to Our World”: Experiences of Persons Living with Dementia Prior to and During the COVID-19 Pandemic

Received: 20 June 2023;  Published: 10 August 2023;  doi: 10.21926/obm.neurobiol.2303178

Abstract

People diagnosed with dementia are experts on living with the disease, yet their perspectives are often overlooked in research and practice. The pandemic has amplified health inequities among older adults, but the impact of the pandemic on the lived experience of people living with dementia remains unclear. This qualitative study used a series of 2 virtual focus groups with people living with dementia (N = 7) to explore challenging situations and emotions experienced by community-dwelling people living with dementi [...]

1261 7084

Open Access Original Research

Research and Application of Modified ZSM-5 for the Process of Alkylation of Oil Distillate Fractions

Received: 20 April 2023;  Published: 10 August 2023;  doi: 10.21926/cr.2303021

Abstract

In the oil distillate fraction alkylation process, a modified Zr zeolite ZSM-5 was obtained and studied. The modification was executed using a method that impregnated ZSM-5 with a 5% solution of ZrOCl2∙6H2O. X-ray diffraction studies were conducted on zeolite ZSM-5, zirconyl chloride modifier ZrOCl2∙6H2O, and modified zeolite ZSM-5-ZrO2, which was calcined at temperatures of 200, 400, and 550°C. The results revealed that the phase composition of modified ZSM-5-ZrO2 zeolite samples varied depending on the calcinatio [...]

1364 8220

Open Access Original Research

Carnauba Straw as Feedstock for Solid Biofuel Production

Received: 29 March 2023;  Published: 09 August 2023;  doi: 10.21926/aeer.2303043

Abstract

Carnauba straw (Copernicia prunifera), residual biomass derived from wax extraction, was evaluated as a potential feedstock for bioenergy production. The characterization was carried out using elemental analysis, proximate analysis, Higher Heating Value (HHV), FTIR spectroscopy, SEM, and FRX. The carbonization, using a Muffle Furnace, was applied as a thermal conversion technique to improve the fixed carbon content, and preliminary densification was done to assess the potential for future production of briquettes. [...]

1384 7777

Open Access Original Research

The Psychometric Properties of the COVID Stress Scales in Korean University Students

Received: 13 April 2023;  Published: 07 August 2023;  doi: 10.21926/obm.neurobiol.2303177

Abstract

The COVID-19 pandemic and its associated disruptions have significantly impacted university students’ lives worldwide. The COVID Stress Scale (CSS) is a 36-item self-reporting instrument designed to measure stress caused by the COVID-19 pandemic. This study purposed to examine the psychometric properties of the Korean version of the CSS for use with Korean university students. The study sample comprised 402 undergraduate students enrolled in a four-year private university in central South Korea. This cross-sectiona [...]

997 6376

Open Access Research Article

Joint Biodiversity Management Committees: A Mechanism to Manage and Conserve Eco-Regions

Received: 31 January 2023;  Published: 07 August 2023;  doi: 10.21926/aeer.2303042

Abstract

Sasthamkotta Lake eco-region is a freshwater Ramsar site in Kerala, India. Eco-regions are ecologically and geographically defined larger land or water mass areas with a characteristic assemblage of the ecosystem and significant biodiversity. A decentralized and locally self-sustaining mechanism has been achieved in managing this eco-region by a participatory model through a joint Biodiversity Management Committee (jBMC) constitution. BMCs are custodians of the environment, and biodiversity, confined to a village/P [...]

1903 10013

Open Access Perspective

Vascular Risks, Aging, and Late-Onset Dementia: Overlapping Etiologies Point to 'Scavenger Receptor'-Mediated Therapeutics

Received: 25 March 2023;  Published: 04 August 2023;  doi: 10.21926/obm.geriatr.2303244

Abstract

Early changes in systemic vascular stiffness and endothelial function can contribute to altered cerebrovascular hemodynamics and impaired cognitive function; additionally, these vascular changes point to potential targets for prevention and treatment strategies in people with mild cognitive impairment. Although the pathogenic mechanisms underlying these vascular changes are heterogeneous and complex, one common feature is the development of cerebral blood flow (CBF) dysregulation, resulting in chronic cerebral hypo [...]

1049 5643

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