Table of Content

Open Access Original Research

‘A Way of Being in the World’: An Exploration of the Experience of Developing Self-Compassion through Online Training

Received: 21 September 2021;  Published: 23 November 2021;  doi: 10.21926/obm.icm.2104050

Abstract

Compassion Focused Therapy (CFT) has increasingly been shown to have a positive impact for people experiencing a range of difficulties, and online self-help formats could provide a way of increasing its accessibility and scalability. This study explored adult participants’ subjective experiences of engaging with online self-compassion training drawn from Compassionate Mind Training (CMT) and CFT. Semi-structured interviews were conducted with 15 participants who had completed online self-compassion training, [...]

1478 10751

Open Access Review

Bacterial Infections after Liver Transplantation: Updates in Post-Surgical Infections, Vancomycin-Resistant Enterococcus, and Multi-Drug Resistant Enterobacteriaceae

Received: 29 March 2018;  Published: 02 November 2018;  doi: 10.21926/obm.transplant.1804023

Abstract

Liver transplantation is a life-saving procedure available worldwide. Despite advances in its surgical and immunosuppressive strategies, infectious complications carry significant morbidity and mortality. Bacterial infections are the most common infective etiologies, and the majority are seen during the first four weeks post liver transplantation. Infectious complications are often intra-abdominal in origin, such as biliary complications and abdominal abscesses. Infections due to multi-drug resistant organisms are [...]

1478 11482

Open Access Case Report

A Case of Disseminated Cryptococcus Post-Kidney Transplant

Received: 28 October 2022;  Published: 19 April 2023;  doi: 10.21926/obm.transplant.2302182

Abstract

Cryptococcosis is a common invasive fungal infection in solid organ transplant recipients (SOTR) that can be challenging to manage. We discuss a case of disseminated cryptococcosis in a transplant recipient. A 26-year-old woman with a history of ESRD from C1q nephropathy, living-related kidney transplant in early 2012, and allograft nephrectomy in 2015, received a deceased donor kidney transplant (DDKT). Induction after the first transplant was anti-thymocyte globulin (ATG) and maintenance immunosuppression (IS) in [...]

1478 8343

Open Access Editorial

Artificial Intelligence Applications in Digital Anthropometry 1

Received: 21 December 2022;  Published: 26 December 2022;  doi: 10.21926/obm.icm.2204056

Abstract

Anthropometric measurements are frequently used to assess changes in body composition in different populations. Despite being a cheap, in-field, and relatively valid technique, the COVID-19 pandemic has impulse research on digital anthropometry across the globe. Machine learning, as the convergence of artificial intelligence and data mining, has the potential to improve data collection and analysis in the applications of kinanthropometry. Far from replacing conventional methods, digital anthropometry is a powerful [...]

1477 10490

Open Access Original Research

Co-development of Low-speed Electric Community Buses for Local Area Revitalization

Received: 10 October 2022;  Published: 02 February 2023;  doi: 10.21926/jept.2301005

Abstract

This paper describes the development of low-speed electric community buses (LSECBs) designed by the author's group and their spread situation in Japan. LSECBs are electric vehicles that can travel on public roads at speeds of less than 5.56 m/s (20 km/h). The university, local government, local businesses, and residents with a co-design approach developed the LSECBs. They have various advantages such as safety due to low speed and low energy consumption. In particular, the LSECBs have features not found in ordinary [...]

1476 8881

Open Access Original Research

Heavy Metal Concentration and Health Risk Assessment of Selected Fruits Sold in Jos Metropolis

Received: 27 February 2021;  Published: 12 May 2021;  doi: 10.21926/acr.2102013

Abstract

The present study investigated the level of heavy metals in selected fruits sold commonly in Jos, Nigeria. The fresh fruits (Avocado pear, Black currant, Egg Plant, Golden melon, and Soursop) were purchased from five major markets (Terminus, Farin Gada, Building materials, Bukuru, and Fobur) in Jos. Each fruit sample was collected in triplicate and analyzed using standard procedures. The concentration of heavy metals (Fe, Cu, As, Cd, Zn, Pb, Mn, and Cr) was determined using Graphite Furnace Atomic Absorption Spectr [...]

1475 8425

Open Access Research Article

Standardized Precipitation Index Comparison along the Limbe-Bamenda Axis of the Cameroon Gulf of Guinea

Received: 19 October 2021;  Published: 12 January 2022;  doi: 10.21926/aeer.2201002

Abstract

Mean monthly rainfall decline with continentality is a commonplace phenomenon that has been used in this study to compare its trend in Bamenda in the Western Highlands and Limbe on the Atlantic lowland coast. This study attempts to bridge some of the methodological gaps in the previous studies on rainfall variability in Cameroon that had emphasized only the inter-annual variability and coefficient of variation without focusing on the specific indices and contrasts between different ecological zones. In this study, [...]

1475 10026

Open Access Original Research

Assessment of Heavy Metal Contamination on Road Dust: A Case Study of Khulna City

Received: 06 September 2024;  Published: 20 January 2025;  doi: 10.21926/aeer.2501008

Abstract

The concentration of heavy metals in road dust poses significant risks to human health and the environment. This study investigates the characteristics of road dust, focusing on the contamination level of heavy metals like lead (Pb), iron (Fe), and arsenic (As). Road dust samples were collected from various locations in Khulna city. They went through acid digestion to determine the Pb, Fe, and As levels using ICP-OES, and bioavailable iron was assessed by mixing the dust samples with water. This study found no dete [...]

1475 9653

Open Access Short Communication

Newborn Screening in Latin America: A Window on the Evolution of Health Policy

Received: 22 August 2021;  Published: 21 January 2022;  doi: 10.21926/obm.genet.2201146

Abstract

Investigating the historical origins of a well-accepted health program across a region, such as newborn screening in Latin America, has the potential to reveal the role of historically-specific drivers in shaping national health policy. We reviewed published reports on NBS in Latin America and interviewed newborn screening experts with experience in the region. We found trends suggesting that the decrease in infant mortality may be a prerequisite to investing in nationwide screening for rarer conditions. We also no [...]

1475 11314

Open Access Research Article

Arginine and Histidine-modified Layered Double Hydroxides Facilitate Transgene Expression in Cancer Cells in Vitro

Received: 14 June 2023;  Published: 21 September 2023;  doi: 10.21926/obm.genet.2303193

Abstract

Layered double hydroxides (LDHs) have interesting properties and structures that enable them to carry nucleic acids, such as deoxyribonucleic acid (DNA). This study synthesized LDHs using the co-precipitation method and functionalized with the amino acids arginine (Arg) and histidine (His) to promote proton-sponge activity for enhanced transgene expression. The LDHs were characterized using X-ray diffraction (XRD), transmission electron microscopy (TEM), and nanoparticle tracking analysis (NTA). The interaction of [...]

1474 7114

Open Access Original Research

A Clinical Validity-Preserving Machine Learning Approach for Behavioral Assessment of Autism Spectrum Disorder

Received: 31 May 2022;  Published: 30 September 2022;  doi: 10.21926/obm.neurobiol.2203138

Abstract

Autism spectrum disorder (ASD) is a neuropsychiatric disorder associated with critical challenges related to social, communication, and behavioral issues. Recent studies have proposed machine learning (ML) techniques for rapid and accurate assessment of ASD. However, the mismatch between the ML techniques and the clinical basis of ASD assessment reduces the effectiveness of ML-based assessment tools. The present study proposed an approach that utilized the potential of ML modeling and preserved the clinical relevan [...]

1474 7900

Open Access Original Research

Impacts of Different Sources of Carbonates on Growth of Fusarium oxysporum f. sp. lycopersici in Different Growth Media

Received: 18 November 2022;  Published: 13 November 2023;  doi: 10.21926/aeer.2304049

Abstract

Fusarium is the most common soil-borne pathogen that causes wilt in many plant crops, among which the tomato is one of the most susceptible crops. This experiment is conducted to analyse the impacts of inorganic carbon compounds i.e., calcium carbonate CaCO3, sodium carbonate Na2CO3 and potassium bicarbonate KHCO3 on the growth of Fusarium oxysporum f. sp. lycopersici (FOL) causing wilt in tomato plant in different culture media including Malt Extract Agar (MEA), Potato Dextrose Agar (PDA) and V8. Three concentrati [...]

1473 7411

Open Access Review

Heart Failure in Elderly People: From Pathophysiology to Diagnosis and Management

Received: 05 March 2023;  Published: 19 September 2023;  doi: 10.21926/obm.geriatr.2303250

Abstract

As the older population increases, there is an increase in age-related chronic diseases, especially heart failure. It affects 25% of over 75-year-old outpatients and represents the leading cause of hospitalization and death in older people. This review aimed to point out the main characteristics concerning heart failure in older people, taking into account clinical symptoms, diagnosis, and treatment. An extensive search on heart failure was made on PubMed and Google, using the keywords older people, heart failure, [...]

1472 13450

Open Access Review

Targeting Acute Islet Inflammation to Preserve Graft Mass and Long-Term Function

Received: 21 November 2018;  Published: 29 January 2019;  doi: 10.21926/obm.transplant.1901043

Abstract

Islet transplantation is a minimally invasive cell based replacement therapy to prevent or reverse diabetes or hypoglycemia through natural hormonal responses to regulate blood glucose. However, extending the islet graft functional lifespan remains a challenge that prevents long-term success and widespread use of the procedure. Islets are subject to stress and damage and undergo immunological assault during transplantation procedures. Current treatments to prevent immune reactivity toward the graft come with toxic [...]

1472 11130

Open Access Review

The Great Masquerade: Donor-derived Infections with Uncommon Central Nervous System Pathogens

Received: 29 January 2021;  Published: 02 May 2021;  doi: 10.21926/obm.transplant.2102141

Abstract

Donor-derived infections (DDI) are an infrequent event in solid organ transplant (SOT) due to advances in screening recommendations, prophylaxis, and surveillance of common infections. However, unexpected pathogen transmission can still occur when a donor is not known to be infected prior to organ procurement, which can lead to significant morbidity and mortality in the organ recipient. Solid organ donors with central nervous system (CNS) pathogens are an uncommon but deadly source of unexpected DDI. Clinically rec [...]

1471 94290

Open Access Review

Trajectories and Status of Transgender Elderly Across the World and in Spain: A Narrative Review

Received: 06 November 2023;  Published: 27 February 2024;  doi: 10.21926/obm.geriatr.2401271

Abstract

Older trans people have been largely unaddressed both in the context of the LGBTIQ+ community and in studies on geriatrics and aging. This literature review compiles up-to-date information on transgender elders, providing a summary of the Spanish historical context in which trans people have been raised, and analyzes the areas in which to center possible courses of action and research on a global scale. The themes tackled are the presence of victimization and violence; the effects of medical transition, taking into [...]

1470 10951

Open Access Research Article

Post-mortem 7.0-Tesla Magnetic Resonance Imaging of the Hippocampus in Amyotrophic Lateral Sclerosis

Received: 12 October 2020;  Published: 17 December 2020;  doi: 10.21926/obm.geriatr.2004143

Abstract

Amyotrophic lateral sclerosis (ALS) is reported to be probably linked to frontotemporal lobar degeneration (FTLD). Since FTLD is characterized by severe frontotemporal degeneration along with hippocampal atrophy (HA), the present study used post-mortem 7.0-tesla magnetic resonance imaging to investigate whether a certain degree of HA occurs in the ALS brains as well. The examined post-mortem brain samples comprised 9 from the ALS cases and 17 from the age-matched controls. The hippocampus samples were examined on t [...]

1469 8760

Open Access Original Research

Comparative Analysis of Healthcare Waste Legislation: Alignment and Discrepancies between Federal, State, and Municipal Regulations

Received: 02 July 2025;  Published: 11 November 2025;  doi: 10.21926/aeer.2504031

Abstract

The management of healthcare waste (HCW) presents a significant environmental and public health challenge, aggravated by gaps in current Brazilian federal regulations. This study provides a comprehensive analysis of specific state and municipal legislation on HCW, comparing it with ANVISA Resolution No. 222/2018 and CONAMA Resolution No. 358/2005 to ascertain whether local regulations enhance management practices and can act as supplementary instruments to federal guidelines. The methodology was structured into thr [...]

1468 7325

Open Access Perspective

Perspectives on the Neurobiology of Antipsychotic Drugs in Psychiatric Disorders

Received: 22 February 2019;  Published: 14 March 2017;  doi: 10.21926/obm.neurobiol.1701001

Abstract

Antipsychotics have been a pillar in the treatment of schizophrenia since their introduction more than 60 years ago. Their variety in structures and receptor binding properties confers on them a complex clinical profile of effectiveness and risk of adverse side-effects. Although antipsychotics are best known for their therapeutic effects in schizophrenia, these are limited to the positive symptoms, with much less influence on negative symptoms or cognitive deficits. Moreover, although the newer (so-called second-ge [...]

1468 12991

Open Access Editorial

Epigenetics is Here to Stay

Received: 24 April 2019;  Published: 30 April 2019;  doi: 10.21926/obm.genet.1902075

Abstract

none

1464 7988

Open Access Research Article

The Lived Experience of Individuals with Chronic Traumatic Brain Injury: An Adapted Group Yoga Intervention

Received: 04 November 2018;  Published: 16 December 2018;  doi: 10.21926/obm.icm.1804033

Abstract

Background: An adapted yoga intervention was delivered to seven individuals with chronic traumatic brain injury. The purpose of this study was to explore and describe the participants' experience of engaging in the 8-week intervention. Methods: Using a phenomenological design, data were collected, analyzed, and coded to generate themes regarding experiences that occurred, how experiences occurred, and why experiences occurred. Results: Participants described experiencing the yoga intervention as a process: from ini [...]

1464 9436

Open Access Original Research

Nature Connection, Mindfulness, and Wellbeing: A Network Analysis

Received: 15 September 2022;  Published: 06 November 2023;  doi: 10.21926/obm.icm.2304050

Abstract

Relationships between nature connection, mindfulness and wellbeing have been observed through nature based therapeutic interventions, where mindfulness and nature appear to reciprocally influence each other in relation to wellbeing and is potentially consistent with attention restoration theory. However, previous studies have relied on examining nature based interventions rather than the role of nature connection in everyday lives. This investigation explored the relationship between nature connection, mindfulness, [...]

1464 12167

Open Access Review

Can HCV Viremic Organs Be Used in Liver Transplantation to HCV Negative Recipients?

Received: 02 February 2020;  Published: 24 April 2020;  doi: 10.21926/obm.hg.2002046

Abstract

Liver transplantation has steadily increased worldwide resulting in a large number of patients on the waiting list. Due to the opioid epidemic in the US, the pool of Hepatitis C seropositive donors increased significantly in recent years. Direct acting antivirals played an instrumental role in making liver transplantation with hepatitis C positive allograft an acceptable option. Although hepatitis C positive liver transplantation to hepatitis C positive recipients is a common practice, there is limited data and agr [...]

1463 7505

Open Access Research Article

Life Cycle Assessment of North American Laminated Strand Lumber (LSL) Production

Received: 18 June 2021;  Published: 15 December 2021;  doi: 10.21926/rpm.2104048

Abstract

Raw materials for buildings and construction account for more than 35% of global primary energy use and nearly 40% of energy-related CO2 emissions. The Intergovernmental Panel on Climate Change (IPCC) emphasized the drastic reduction in GHG emissions and thus, wood products with very low or negative carbon footprint materials can play an important role. In this study, a cradle-to-grave life cycle assessment (LCA) approach was followed to quantify the environmental impacts of laminated strand lumber (LSL). The inven [...]

1463 12647

Open Access Review

Novel Insights into Epigenetic Control of Autophagy in Cancer

Received: 28 June 2022;  Published: 08 November 2022;  doi: 10.21926/obm.genet.2204170

Abstract

The autophagy mechanism recycles the damaged and long-standing macromolecular substrates and thus maintains cellular homeostatic and proteostatic conditions. Autophagy can be an unavoidable target in cancer therapy because its deregulation leads to cancer formation and progression. Cancer can be controlled by regulating autophagy at different genetic, epigenetic, and post-translational levels. Epigenetics refers to the heritable phenotypic changes that affect gene activity without changing the sequence. Modern biol [...]

1462 11660

Open Access Short Communication

Low-Frequency Oscillations for Nonlocal Neuronal Coupling in Shared Intentionality Before and After Birth: Toward the Origin of Perception

Received: 09 May 2023;  Published: 02 November 2023;  doi: 10.21926/obm.neurobiol.2304192

Abstract

The theoretical study observes literature to understand whether or not low-frequency oscillations can simultaneously alter the excitability of neurons from peripheral nervous subsystems in different individuals to provide Shared Intentionality in recipients (e.g., fetuses and newborns) and what are the attributes of ecological context for Shared Intentionality. To grasp the perception of objects during environmental learning at the onset of cognition, a fetus needs exogenous factors that could stimulate her nervous [...]

1462 17741

Open Access Review

Advances in Quantum Properties of Graphene and Derivatives Applied to Functional Nanomaterials and Metamaterials

Received: 30 December 2022;  Published: 13 February 2023;  doi: 10.21926/rpm.2301008

Abstract

In the present work we describe the most important quantum properties of graphene and derivatives recently published. We discuss how these properties were incorporated into varied hybrid materials such as substrates for specific tuning of matter to track varied quantum signals. Their potential applications were analyzed from nanomaterial and nanotechnology. In particular graphene, its derivatives and other carbon-based allotropes were chosen due to their special chemical structure and properties from the nanoscale [...]

1462 10542

Open Access Concept Paper

Using Elder Abuse Case Studies to Develop LGBTQ+ Cultural Competency

Received: 16 July 2023;  Published: 15 January 2024;  doi: 10.21926/obm.geriatr.2401266

Abstract

Lesbian, gay, bisexual, transgender, and queer (LGBTQ+) elders are vulnerable to both the “usual” types of elder abuse (physical, sexual, emotional, and financial abuse, along with neglect), and with abuse that is specific to the context and history of LGBTQ+ elders. Training for adult protective services, long-term care ombudsmen, and other professionals who work with abused elders therefore should include information and skill-building in responding to this population. Research into effective training about LGBTQ [...]

1461 7941

Open Access Research Article

COVID on the Brain: Anxiety Sensitivity and Mindful Awareness Mediate the Relationship between COVID-19 Obsession and Anxiety

Received: 03 October 2021;  Published: 01 December 2021;  doi: 10.21926/obm.icm.2104053

Abstract

The coronavirus (COVID-19) pandemic has produced a global mental health crisis and many individuals have obsessive thoughts and worry about COVID-19 which may, both directly and indirectly, relate to more general anxiety. This study explored anxiety sensitivity and mindful awareness as mediators in the relationship between COVID-19 obsession and general anxiety. College student participants (N = 172) completed the Obsession with COVID-19 scale, the Anxiety Sensitivity Index, the awareness subscale of the Five Facto [...]

1461 9579

Open Access Research Article

Architecture as Habitat: Enhancing Urban Ecosystem Services Using Building Envelopes

Received: 13 August 2021;  Published: 09 November 2021;  doi: 10.21926/aeer.2104029

Abstract

The practice of reconciliation ecology in urban environments relies heavily on urban green space as the primary source of vegetated habitat in cities. However, most cities lack the quantity, connectivity, and accessibility of green space needed to provide essential ecosystem services for the health, well-being, and resilience of human and non-human species. In reaction to urban densification and the increasing frequency and severity of climate change impacts, this study argues that architecture could strategically [...]

1460 15671

Open Access Research Article

Association between Very Low Dietary Protein Intake and Subsequent Falls in Community-Dwelling Older Adults in the United States

Received: 10 April 2020;  Published: 22 May 2020;  doi: 10.21926/obm.geriatr.2002120

Abstract

Poor nutrition is linked to frailty and both poor nutrition and frailty are recognized risk factors for falls. This study examined the association between dietary protein intake and subsequent reported falls in community-dwelling older Americans with a history of falls. Other nutritional, functional, and sociodemographic-related variables were also considered in our model. This was a retrospective analysis using data from the U.S. Health and Retirement Study (HRS) and Health Care and Nutrition Study (HCNS), both fu [...]

1460 68833

Open Access Research Article

Permeability, Compressibility and Pressure Prediction in Supercharged Wireline and FTWD Environments

Received: 12 April 2023;  Published: 10 July 2023;  doi: 10.21926/jept.2303023

Abstract

In conventional wireline and LWD/MWD formation testing, downhole predictions for rock and fluid properties are based on simplified Darcy flow models, but only for mathematical expediency. These require initially constant pressures that are uniform throughout the reservoir. This limitation precludes common applications in overbalanced drilling, so that supercharge or near-well invasion effects - associated with rapidly decreasing pressures at the sandface where pressures are measured - are completely ignored. Such 1 [...]

1460 7946

Open Access Original Research

Loneliness Among African Migrants Living in Portugal

Received: 23 January 2022;  Published: 08 June 2022;  doi: 10.21926/obm.neurobiol.2202125

Abstract

This study analyzed the degree of loneliness, as well as acculturation and adaptation factors related to it among African migrants. The study sample consisted of 759 migrants (48.5% females) from four ethnocultural groups (Angolans, Cape Verdeans, Guineans, and Mozambicans) living in Portugal. Participants’ mean age was 37 years, and the mean length of sojourn in this country was 21 years. Participants completed self-reported questionnaires to evaluate social contacts, language proficiency, ethnic identity, perceiv [...]

1460 10722

Open Access Original Research

“Look, It’s a Dengue Mosquito”: A Qualitative Study on Living Near Open-Air Dumpsites and Vector-Borne Diseases

Received: 11 May 2023;  Published: 30 August 2023;  doi: 10.21926/aeer.2303045

Abstract

Currently, almost half of the human population is at risk of acquiring dengue. Other emerging pathogens affecting human populations transmitted by Aedes (Stegomyia) aegypti are chikungunya and Zika viruses. People who live in poor areas are more susceptible to be infected by these diseases. The lack of selective garbage collection and inadequate water storage are important factors in the dynamics of vector-borne transmission. This study took place in Estrutural City, the poorest city in Brasilia, Brazil, which host [...]

1459 12702

Open Access Case Report

A Case Study on the Impact of Transportation of Mass Timber Products on the Cradle-to-Gate LCA Results for an Institutional Building

Received: 21 April 2022;  Published: 05 August 2022;  doi: 10.21926/rpm.2203014

Abstract

Mass timber products (MTPs) are being adopted in new building constructions and remodels in the last three decades, credited to their renewable and low carbon footprint characteristics. However, there are no mass timber manufacturers currently existing in Atlantic Canada. Extended distances of transporting MTPs to this region from other Canadian provinces may sacrifice the environmental benefits of using MTPs. This study was aimed to understand, via conducting a cradle-to-gate life cycle assessment (LCA), the envir [...]

1458 11635

Open Access Review

Nanomaterials with Plant or Animal Origin for Greener Biodelivery and Biosensor Applications: A Review

Received: 26 October 2022;  Published: 12 June 2023;  doi: 10.21926/rpm.2302023

Abstract

Nanomaterials are now used in almost every field of science; as conductors and electrodes in electronics, as nanodelivery systems in health screenings and drug delivery, as nanofibrils in filtering and textile industry, as nanoparticles in biosensor fabrication for toxin and pathogen detection, and in packaging materials in the food industry. Synthetic materials and plastics accumulate in the environment causing increasing health concerns for their use in food and pharmaceutical products. Therefore, researchers now [...]

1458 7793

Open Access Original Research

Comparison of Heavy Metal and Disinfectant Resistance of S. aureus and Enterococcus Isolates with Antibiotic Resistance Profiles

Received: 31 July 2024;  Published: 05 January 2025;  doi: 10.21926/obm.genet.2501278

Abstract

Antimicrobial resistance is one of the most significant threats to our present and future. Recently, it has been suggested that antibiotic-resistant microorganisms also exhibit resistance to heavy metals and disinfectants, and these resistance profiles may interact with each other. Microorganisms can be exposed to heavy metals and disinfectants in different ways in various environments. They are especially likely to be exposed to quaternary ammonium compounds used in the food industry or heavy metals due to tap wat [...]

1457 6838

Open Access Case Report

Daily Observations of Preserved Cognition and Quality of Life after Multiple Therapies for Postmortem-Verified Severe Alzheimer’s

Received: 15 February 2019;  Published: 18 April 2019;  doi: 10.21926/obm.geriatr.1902048

Abstract

Background: Cognitive abilities in Alzheimer’s Disease are usually examined by formal tests conducted in a laboratory or facility. Such tests are useful for determining the severity of the disease but do not indicate the types of cognition exhibited in the daily lives of patients. This study shows significant preservation of cognition and quality of life in the daily routine of a woman with severe Alzheimer’s who was given multiple therapeutic interventions. Alzheimer’s disease involves multiple d [...]

1457 9549

Open Access Review

Neurostimulation for Traumatic Brain Injury: Emerging Innovation

Received: 07 October 2022;  Published: 06 March 2023;  doi: 10.21926/obm.neurobiol.2301161

Abstract

Traumatic brain injury (TBI) is a significant source of brain deficit and death among neurosurgical patients, with limited prospects for functional recovery in the cases of moderate-to-severe injury. Until now, the relevant body of literature on TBI intervention has focused on first-line, invasive treatment options (namely craniectomy and hematoma evacuation) with underwhelming focus on non-invasive therapies following surgical stabilization. Recent advances in our understanding of the impaired brain have encourage [...]

1457 9973

Open Access Case Report

Macroscopic Aspergillus Infection at the Anastomosis of a Lung Transplant Recipient

Received: 25 October 2020;  Published: 03 July 2021;  doi: 10.21926/obm.transplant.2103147

Abstract

A 65-year-old female with a history of right lung transplantation (LTx) for chronic obstructive pulmonary disease (COPD) 9-years prior complicated by grade 3 bronchiolitis obliterans syndrome (BOS) was admitted to the hospital for chest pain and dyspnea on exertion (DOE). Her bronchoscopy revealed fluffy, endobronchial lesions that were adherent to the right sided anastomosis resulting in mild obstruction of the right mainstem bronchus. Pathology from biopsies of the endobronchial lesions revealed hyphal fungal org [...]

1457 8356

Open Access Communication

Biocatalyzed Hydrolysis of Residual Oils and Proteins from Flax and Camelina Oilseed Press Cakes Using Lipase and Protease

Received: 14 September 2022;  Published: 17 November 2022;  doi: 10.21926/cr.2204041

Abstract

In this study, a PoC (Proof of Concept) of a possible biomass valorization of flax and camelina oilseed press cakes was presented. Biocatalyzed hydrolysis of residual oils and proteins extracted from these wastes was studied. The biotransformation of oils was performed using commercial immobilized lipases, including Amano PS, Amano AK, and Candida Antarctica Lipase B (CALB). Acylglycerols were partially or fully hydrolyzed using Amano PS and AK. Triglycerides were not hydrolyzed by CALB, which behaved differently. [...]

1456 7702

Open Access Review

Models for Predicting Risk of Acute Kidney Injury after Liver Surgery

Received: 05 February 2018;  Published: 16 May 2018;  doi: 10.21926/obm.hg.1802007

Abstract

Background & Aims. Acute kidney injury (AKI) is a serious complication of liver surgery and associated with significant morbidity and mortality. The incidence of AKI following hepatic surgery can be as high as 94%, with highest rates seen following orthotopic liver transplantation, particularly when extended criteria grafts are used. Strategies to identify patients at risk of AKI may enable early interventions to prevent or minimise AKI. Methods. A systematic review was conducted using PubMed, Medline, Cochrane and [...]

1454 6441

Open Access Research Article

Developing a Compassion Focused Supervision Model for Senior Leaders in Education

Received: 22 March 2024;  Published: 11 June 2024;  doi: 10.21926/obm.icm.2402033

Abstract

This article describes the development and delivery of a novel model of supervision for senior teachers in schools, informed by Compassion Focused Therapy (CFT). It explores whether this model can be considered acceptable and valuable to senior teachers, and is able to be delivered by multiple supervisors using a manual. Surveys, interviews, and focus groups were used to gather feedback about the value and impact of the supervision. Data were gathered from 39 senior teachers across three phases to assess feedback o [...]

1454 8977

Open Access Review

Neurochemical System Involved in Anorexia Nervosa

Received: 19 November 2019;  Published: 13 April 2020;  doi: 10.21926/obm.neurobiol.2002055

Abstract

Anorexia nervosa is a psychiatric disorder, the etiopathogenesis of which is still not fully understood. Currently, the most accredited model is a multifactorial model, which involves interaction between predisposing factors of biological nature, partly genetically determined, and psychological/personological and environmental socio-cultural factors. The last 20 years have led to the advancement in our knowledge on the mechanisms of energy homeostasis maintenance. There has been a veritable explosion of studies aim [...]

1454 12138

Open Access Review

Optimizing Lymphedema Outcomes through Lifestyle

Received: 11 January 2023;  Published: 17 March 2023;  doi: 10.21926/obm.icm.2301016

Abstract

Lymphedema, a chronic incurable condition characterized by edema, inflammation, reactive fibrosis, adipose proliferation, and compromised immune function, affects over 250 million people worldwide [1]. Further, a comorbidity of obesity increases the risk of developing lymphedema and can result in irreversible damage to lymphatic function. Access to appropriate and timely lymphedema treatment, performance of proper self-management strategies, and implementation of healthy lifestyle practices are critical for optimal [...]

1452 21477

Open Access Original Research

Human Attention Assessment Using A Machine Learning Approach with GAN-based Data Augmentation Technique Trained Using a Custom Dataset

Received: 27 May 2022;  Published: 04 October 2022;  doi: 10.21926/obm.neurobiol.2204139

Abstract

Human–robot interactions require the ability of the system to determine if the user is paying attention. However, to train such systems, massive amounts of data are required. In this study, we addressed the issue of data scarcity by constructing a large dataset (containing ~120,000 photographs) for the attention detection task. Then, by using this dataset, we established a powerful baseline system. In addition, we extended the proposed system by adding an auxiliary face detection module and introducing a unique GAN [...]

1452 11896

Open Access Review

Analysis of Migraine Pathophysiology by Magnetic Resonance Imaging

Received: 25 October 2021;  Published: 08 February 2022;  doi: 10.21926/obm.neurobiol.2201115

Abstract

Magnetic resonance imaging (MRI) has been used to investigate migraine pathophysiology because it is a non-invasive technique. The main aim of clinical imaging for patients with headaches is to exclude secondary headaches due to organic lesions. Conventional structural imaging techniques such as routine MRI demonstrate white matter lesions, changes in gray matter volume or cortical thickness, and cerebral blood flow in patients with migraine. Changes in metabolite levels are observed by magnetic resonance spectrosc [...]

1451 10451

Open Access Commentary

Targeting Neuroplasticity for the Management of Pain and Agitation in Alzheimer’s Disease via Bergamot Nanotherapy

Received: 05 July 2022;  Published: 14 September 2022;  doi: 10.21926/obm.neurobiol.2203133

Abstract

Alzheimer’s disease (AD) accounts for 50–70% of cases of dementia worldwide and is a social burden to the affected population. Although several pathogenetic hypotheses have been proposed, evidence favoring the role of aberrant neuroplasticity in the development of the neuropsychiatric symptoms associated with dementia is increasing. Specifically, agitation is resistant to treatment and affects the quality of life, also because of the lack of safe and effective treatment for AD. Alterations in pain processing due to [...]

1451 8340

Open Access Research Article

Concentrations of Gaseous Elemental Mercury in the Atmosphere of a Mediterranean Coastal Site in Greece

Received: 25 January 2021;  Published: 04 May 2021;  doi: 10.21926/aeer.2102007

Abstract

Gaseous elemental mercury (GEM) was monitored in the atmosphere of a coastal site situated in the Northern Aegean Sea of Greece from August 2014 to January 2015. The selected sampling site is seldom impacted by human activities. Thus, it was possible to study the processes involved in natural terrestrial, aquatic, and atmospheric environments. The diurnal and monthly variations in the concentration of GEM as well as the factors influencing these variations were determined. The GEM concentrations were found to be in [...]

1450 10407

Open Access Short Report

Fabrication of Perovskite Solar Cells by the Smart Stacking Process

Received: 21 September 2022;  Published: 25 November 2022;  doi: 10.21926/jept.2204038

Abstract

The most commonly used process for fabricating perovskite solar cells is based on wet chemistry, which greatly limits the choice of materials suitable for optimizing the performance of the device. We developed a new approach for the fabrication of perovskite-based solar cells. In the smart stacking process, the perovskite solar cell was assembled by stacking two pieces of perovskite films prepared separately. A working perovskite solar cell was developed with PCE = 0.78% and the perovskite layer was analyzed with X [...]

1450 8363

TOP