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Open Access Review

Efficacy of Biofield Therapies in Alleviating Pain and Reducing Symptoms Associated with Mental Disorders: A Systematic Review and Meta-Analysis

Received: 23 March 2026;  Published: 02 June 2026;  doi: 10.21926/obm.icm.2602021

Abstract

Biofield therapies (BTs) including Reiki, Therapeutic Touch (TT), Healing Touch (HT), and External Qigong Treatment (EQT) are non-pharmacological interventions proposed to modulate putative energy fields surrounding the human body. Despite growing clinical interest, the evidence base remains methodologically heterogeneous. This study aimed to provide a rigorous synthesis of randomized controlled trial (RCT) evidence on the efficacy of BTs for pain reduction and for the alleviation of symptoms associated with mental [...]

20 96

Open Access Original Research

Clinical Manifestation of Osteogenesis Imperfecta in Indonesian Patients: A Multi-Centre Study

Received: 22 January 2026;  Published: 02 June 2026;  doi: 10.21926/obm.genet.2602344

Abstract

Osteogenesis Imperfecta (OI) is a rare genetic disorder caused by mutations in genes that encode collagen, with varying clinical presentations. While some studies in Indonesia have reported OI’s clinical features and treatments, there is a lack of comprehensive national data, with limited awareness and access to specialized care for affected individuals. This collaborative study, involving multiple centres across Indonesia, aims to address data fragmentation by analyzing patient characteristics, clinical manifestat [...]

16 106

Open Access Original Research

Psychosocial Death Education in Schools: Insights from Experienced Practitioners

Received: 21 November 2025;  Published: 29 May 2026;  doi: 10.21926/obm.neurobiol.2602338

Abstract

Death Education is an emerging field aimed at developing psychological and social competencies for engaging with death and dying. This qualitative study explored the experiences of 17 professionals—including psychologists, teachers, and spiritual counselors—implementing Death Education interventions in schools. Semi-structured interviews were analyzed thematically, revealing four key domains: (1) facilitators’ personal relationship with death and motivation; (2) children’s and adolescents’ representations of death; [...]

57 210

Open Access Original Research

Does Accepting a Wider Variety of Foods Mean Eating Better? The Food Paradox of Children and Adolescents with Feeding Difficulties

Received: 18 December 2025;  Published: 29 May 2026;  doi: 10.21926/rpn.2602006

Abstract

This study descriptively investigates the food acceptance patterns and dietary profiles of neurotypical infants, children, and adolescents with Feeding Difficulties (FD) at a Brazilian pediatric reference center. It further examines whether a broader food repertoire translates into improved nutritional quality. The research, an observational, analytical cross-sectional study, analyzed data from 237 patients aged 10 to 204 months with FD. Findings revealed a discrepancy between family perceptions and professional as [...]

70 281

Open Access Review

Applications of CRISPR-Cas9 Gene Editing Technology in Food Allergy Therapy: A Comprehensive Review

Received: 06 January 2026;  Published: 29 May 2026;  doi: 10.21926/rpse.2602009

Abstract

Worldwide, the incidence of allergenicity is rising rapidly, making it an ongoing clinical challenge and public health concern. The current treatment options for allergies include allergen avoidance, medications to improve symptoms, and immunotherapy to desensitize affected individuals to specific allergens. However, these approaches have limitations, and there is an urgent need for novel and more effective therapies. Allergies are a compelling candidate for gene editing (GE) given their prevalence and the inadequa [...]

57 302

Open Access Research Article

A Compassionate Mind: A Qualitative Evaluation of Compassion Focused Group Therapy for Complex Interpersonal Trauma

Received: 11 October 2025;  Published: 28 May 2026;  doi: 10.21926/obm.icm.2602020

Abstract

A significant percentage of the population attending local adult psychology services have experienced variable forms of maltreatment from a young age and by a close attachment figure. For those who do not present with post-traumatic stress disorder symptoms, they may be misunderstood and offered a phase-based approach to their care. Although a stepped care approach to complex trauma is in keeping with current guidelines this often includes lengthy periods of group-based psychoeducation and skills development that o [...]

65 254

Open Access Original Research

Assessing Land Use Dynamics and Thermal Stress in Ahmedabad Using Integrated Remote Sensing and Machine Learning Techniques

Received: 01 March 2026;  Published: 27 May 2026;  doi: 10.21926/aeer.2602011

Abstract

The rapid urbanisation in developing countries has not only intensified land transformation but also significantly altered surface temperatures, thereby increasing climate vulnerability. Ahmedabad, one of India’s fastest-growing cities, has witnessed substantial urban growth over the past two decades and therefore requires an integrated approach to analyse land-use change, thermal dynamics, and future growth patterns. This study aims to analyse the spatial and temporal patterns of land use/land cover (LULC) changes [...]

84 281

Open Access Original Research

Prenatal Diagnosis of Severe Factor VII Deficiency in the Setting of Maternal Breast Cancer

Received: 23 January 2026;  Published: 26 May 2026;  doi: 10.21926/obm.genet.2602343

Abstract

Congenital factor VII (FVII) deficiency is the most common rare bleeding disorder (RBD), presenting with various clinical manifestations. Given the heightened risk of life-threatening bleeding and fatal hemorrhagic complications, prompt detection of the disorder is critical, especially in cases with low FVII levels and a history of familial severe clinical presentations. In such cases, prenatal diagnosis (PND) emerges as a life-saving option. In this study, we reported two PNDs in a family with a positive family hi [...]

91 258

Open Access Original Research

The Inverse Way to Study the Relationship of Diet with Health and Disease

Received: 12 December 2025;  Published: 26 May 2026;  doi: 10.21926/rpn.2602005

Abstract

To study the relationship of dietary score versus age at death (AD) in an extinct cohort at 61 years of follow-up, based on an “inverse” procedure. Data from the Italian Rural Areas (IRA) of the Seven Countries Study of Cardiovascular Diseases, made up of 1712 middle-aged men followed for 61 years, were used. The “direct” approach means applying a dietary score to each subject of a cohort and, by means of a model, estimating the probabilities of events for different dietary score levels. The “inverse” approach, ins [...]

100 290

Open Access Original Research

Enhancing Bone Union in Aseptic Femoral Shaft Nonunion by Multimodal Autologous Bone Graft and Mechanical Stabilization

Received: 16 November 2025;  Published: 26 May 2026;  doi: 10.21926/obm.transplant.2602271

Abstract

Aseptic femoral shaft nonunion represents a biologically compromised state in which impaired osteogenesis, insufficient vascularity, and inadequate mechanical stability prevent healing. Although mechanical revision is essential, achieving union often requires effective autologous bone tissue transplantation and biologic stimulation. This study evaluated a multimodal revision strategy integrating structural and cancellous autografts with mechanical reconstruction to restore both biological viability and stability at [...]

74 284

Open Access Original Research

Application of Unmanned Aerial Vehicles in Assessing the Current Condition and Closure Design of Da Mai Landfill (Vietnam)

Received: 24 December 2025;  Published: 25 May 2026;  doi: 10.21926/aeer.2602010

Abstract

Municipal solid waste (MSW) landfills remain a major source of greenhouse gas emissions, leachate pollution, and land degradation, particularly in low- and middle-income countries where many sites operate beyond their design capacity. This study proposes an integrated and low-cost framework combining unmanned aerial vehicle (UAV) photogrammetry with environmental assessment to support landfill closure planning. Using the Da Mai landfill (Vietnam) as a case study, high-resolution orthomosaics and a digital surface m [...]

121 411

Open Access Original Research

Safety and Genoprotective Effects of an 8-Herb Tea–ESSIAC Versus Mate Cocido, An Ilex paraguariensis Infusion

Received: 17 December 2025;  Published: 21 May 2026;  doi: 10.21926/obm.icm.2602019

Abstract

ESSIAC tea is a traditional multi-herb infusion or decoction widely used by cancer patients as a complementary therapy. Originally employed in traditional Ojibwa medicine, it was later reformulated by a Canadian nurse. The classic ESSIAC infusion contains four main botanicals: burdock root (Arctium lappa), Turkish rhubarb root (Rheum palmatum), sheep sorrel (Rumex acetosella), and slippery elm bark (Ulmus rubra). Commercial variations (e.g., FlorEssence® and Genuine ESSIAC™) expand this list to include blessed this [...]

191 569

Open Access Original Research

Genetic Variants in Panamanian Patients with Hereditary Cardiomyopathies

Received: 26 January 2026;  Published: 20 May 2026;  doi: 10.21926/obm.genet.2602342

Abstract

Hereditary Cardiomyopathies (HCs) are defined as genetically determined cardiovascular diseases (CVDs) that frequently exhibit a familial inheritance pattern. These conditions include cardiomyopathies (CMs), arrhythmias (ARs), and other inherited cardiovascular syndromes. In Panama, the national incidence of Hereditary Cardiomyopathies remains unknown. The objective was to identify genetic variants in Panamanian patients diagnosed with HCs or cardiac arrhythmias and subsequently to identify carrier families to prov [...]

216 478

Open Access Original Research

Integrated Assessment and Projection of Urban Expansion and Thermal Dynamics in Bangalore Using Multi-Temporal Landsat Data and Machine Learning Techniques

Received: 12 February 2026;  Published: 19 May 2026;  doi: 10.21926/aeer.2602009

Abstract

Rapid urbanization has remarkably altered land surface characteristics and thermal environments in Indian metropolitan cities, thereby increasing ecological pressure and urban heat risk. This study integrates assessments of land use and land cover (LULC) change and LST, and the UTFVI for Bangalore, India, using multi-temporal Landsat imagery and geospatial techniques, along with machine learning methods. LULC changes were studied and analyzed for 2000 and 2020, and a simulation to 2024 was performed, employing a Ra [...]

144 523

Open Access Case Report

Clinical and Molecular Cytogenetic Characterization of a De Novo 3q26.33-q28 Duplication: Case Report and Literature Review

Received: 06 February 2026;  Published: 19 May 2026;  doi: 10.21926/obm.genet.2602341

Abstract

Isolated duplications of the long arm of chromosome 3 (3q) are rare chromosomal abnormalities. To date, approximately 32 pure cases have been documented. Most reported 3q duplications arise from unbalanced translocations or inversion-loops mechanisms and are associated with additional chromosomal imbalances, making pure duplications particularly valuable for genotype-phenotype correlations. We report a 17-year-old female with a de novo pure tandem duplication of 3q26.33-q28 (~10.945 Mb). The clinical course was mar [...]

205 552

Open Access Review

The Integration of Cognitive Neuroscience Principles in Communication Education: A Comprehensive Review of Curricular Designs and Skill Transfer Efficacy

Received: 02 November 2025;  Published: 18 May 2026;  doi: 10.21926/obm.neurobiol.2602337

Abstract

This review explores the integration of cognitive neuroscience principles into communication education, focusing on how neuroscience-informed curricular designs enhance skill acquisition and transfer. A comprehensive literature search was conducted across primary scientific databases, including PubMed, Scopus, Web of Science, and ERIC, to identify relevant studies published between 2014 and 2025. Following a multi-stage screening process based on predefined inclusion and exclusion criteria, 15 peer-reviewed scienti [...]

212 568

Open Access Research Article

Positive Mental Health and Its Promotion: A Bicultural Perspective and Narrative Synthesis from Aotearoa New Zealand

Received: 20 November 2025;  Published: 18 May 2026;  doi: 10.21926/obm.icm.2602018

Abstract

Positive mental health frameworks in Aotearoa New Zealand have largely been shaped by Western individualist assumptions and have given limited attention to Indigenous and bicultural understandings of wellbeing. This article examines positive mental health and its promotion in Aotearoa New Zealand, through a bicultural lens grounded in Te Tiriti o Waitangi. It reports on two cross-cultural mental health searches and discusses several models of health from te Ao Māori (the Māori world). Based on the view that positiv [...]

215 547

Open Access Original Research

Implementation of General Consent in Swiss Traditional Chinese Medicine Practices: A Cross-sectional Study

Received: 24 November 2025;  Published: 18 May 2026;  doi: 10.21926/obm.icm.2602017

Abstract

Traditional Chinese Medicine (TCM) is often applied in isolated TCM practices, making rigorous research and standardized real-world data collection challenging. The purpose of this study was to implement the general consent (GC) in TCM practices, investigate the issue and the acceptance rate of the GC, and the influencing demographic factors. GC forms were distributed to patients before appointments and collected during their first visits. Logistic regression analyses were performed to investigate demographic facto [...]

149 442

Open Access Review

A Multi-Omics Panorama of Acute Myeloid Leukemia: From Molecular Hallmarks to Clinical Translation

Received: 14 March 2026;  Published: 18 May 2026;  doi: 10.21926/obm.genet.2602340

Abstract

Acute myeloid leukemia (AML) is a heterogeneous hematologic malignancy with genetic and clinical characteristics. Recent advances in multi-omic technologies, including genomics, epigenomics, transcriptomics, proteomics, metabolomics, immunomics, microbiome profiling, and both spatial and single-cell analyses, have greatly enhanced our understanding of AML pathobiology. Substantial multi-omic studies show that recurrent driver mutations not only impart traditional genomic lesions but also participate in chromatin re [...]

252 799

Open Access Original Research

Development of Binderless Waste-Derived Briquettes: Effect of Plastic Content on Combustion Performance and Kinetics

Received: 16 February 2026;  Published: 15 May 2026;  doi: 10.21926/jept.2602009

Abstract

Waste-derived briquettes offer a promising alternative to fossil fuels and are characterised by low production costs, high volumetric calorific value, robust mechanical strength, and excellent durability. To optimize their adoption, four variants of waste-derived briquettes were produced with different mass ratios of sawdust to polyethylene terephthalate (PET) plastic (100:0, 90:10, 80:20, and 70:30) using high-pressure compaction without binders. Thermogravimetric analysis (TGA) and the Coats-Redfern method were e [...]

276 743

Open Access Review

Latest Approaches in Cancer Therapy and Remaining Gaps

Received: 12 December 2025;  Published: 13 May 2026;  doi: 10.21926/obm.genet.2602339

Abstract

Cancer remains one of the major global challenges due to its complex and heterogeneous molecular nature across individuals. Recent advances in technology have enhanced the understanding of cancer’s molecular mechanisms, paving the way for the development of effective therapeutics. These include small-molecule inhibitors and monoclonal antibodies, used to interfere with the oncogenic signaling pathways. Immunotherapy has also emerged as a promising area in cancer therapy, with approaches such as immune checkpoint in [...]

201 575

Open Access Short Review

Potency of Bioflocculants Based on Onggok Cassava Starch Modified by Graft Copolymerization with Polyacrylamide (PAM) and Its Application in Textile Waste Treatment

Received: 07 March 2025;  Published: 13 May 2026;  doi: 10.21926/rpse.2602008

Abstract

The textile industry is a major source of environmental pollution due to the discharge of highly colored and chemically complex wastewater containing toxic, mutagenic, and carcinogenic compounds that are often resistant to conventional treatment. Although conventional chemical coagulants and flocculants such as alum and synthetic polymers are effective, their application raises concerns about excessive sludge generation, residual toxicity, and long-term environmental impacts. This short review critically evaluates [...]

185 637

Open Access Original Research

“Cultivating the Conditions for Safeness”: An Exploration of Patient’s Experiences of a Compassion Focused Group Psychotherapy Program for People with a Diagnosis of Personality Disorder

Received: 11 October 2025;  Published: 12 May 2026;  doi: 10.21926/obm.icm.2602016

Abstract

Individuals who have early attachment trauma can be fearful and resistant to caring behaviour from others and for themselves. This is partly because stimulation of the caring motivational system ignites trauma attachment memory. As a consequence, these individuals are unable to access care-attachment systems, supported by neurobiological processes involving the vagus nerve, oxytocin, and the frontal cortex, for modulating threats and regulating interpersonal distress. This paper outlines a Compassion Focused Group [...]

475 1517

Open Access Original Research

Breaking Cognitive Barriers: Comparing Neurobic and Aerobic Approaches in Dementia Care

Received: 04 December 2025;  Published: 09 May 2026;  doi: 10.21926/obm.neurobiol.2602336

Abstract

The study aimed to compare the effects of neurobic and aerobic approaches in Dementia care. Dementia is a progressive brain disorder that leads to a decline in cognitive abilities, including thinking, reasoning, and memory. In India, it is estimated that 74% of adults aged 60 and older are affected, totaling around 8.8 million individuals. Neurobics refers to exercises designed to enhance oxygen flow and invigorate the brain by engaging in novel activities, situations, or experiences. This may include attending liv [...]

1382 1849

Open Access Research Article

Utilization Patterns and Safety Profile of Immunosuppressive Regimen among Kidney Transplant Recipients: A Descriptive Pharmacoepidemiological Study from a Tertiary Hospital in Indonesia

Received: 27 January 2026;  Published: 09 May 2026;  doi: 10.21926/obm.transplant.2602270

Abstract

Kidney transplantation is the preferred therapy for end-stage kidney disease (ESKD), but long-term success is greatly influenced by the selection and safety of immunosuppressants. Local data on prescribing patterns and the incidence of drug side effects in Indonesia are still limited. Therefore, this study aims to evaluate induction therapy patterns, immunosuppressant maintenance, and the incidence of drug-related side effects among kidney transplant recipients at a tertiary hospital in Yogyakarta, Indonesia. Mater [...]

183 720

Open Access Case Report

Rehabilitation in a Patient with Spastic Quadriplegia and Pneumonia: The Physiatrist’s Point of View Through the Analysis of a Case Report

Received: 17 September 2025;  Published: 08 May 2026;  doi: 10.21926/obm.neurobiol.2602335

Abstract

Patients with severe neurological sequelae often experience profound motor deconditioning that, combined with impaired mucociliary clearance, reduced lung volume, and the presence of tracheostomy, predisposes them to pulmonary infections and serious respiratory complications. A 24-year-old male with spastic quadriplegia secondary to childhood cerebral hemorrhage from an arteriovenous malformation, tracheostomy with a cuffed cannula under mechanical ventilation, and hydrocephalus treated with a ventriculoperitoneal [...]

160 668

Open Access Original Research

Clinical Variabilities of PTPN11 Pathogenic Variant in Indonesian Noonan Syndrome Patients

Received: 08 January 2026;  Published: 06 May 2026;  doi: 10.21926/obm.genet.2602338

Abstract

Noonan syndrome (NS) is an autosomal dominant disorder with a wide spectrum of symptoms and clinical phenotypes, including short stature, congenital heart defects (CHD), and distinctive facial features. A pathogenic variant in the PTPN11 gene is the major cause of NS. This is a preliminary study in Indonesia involving 29 patients with clinical features of NS. Detailed clinical and echocardiography data were collected. Genomic DNA was extracted from a peripheral blood sample. Exome sequencing or PCR followed by Sang [...]

255 948

Open Access Concept Paper

Addressing Perinatal Mental Health and Suicide: Developing an Intervention to Disseminate Tools and Resources to Low Resource Populations

Received: 01 October 2025;  Published: 05 May 2026;  doi: 10.21926/obm.icm.2602015

Abstract

Perinatal mental health challenges are the number one complication of pregnancy and childbearing. Despite the growing need, substantial barriers to addressing perinatal mental health exist, including lack of infrastructure, policies, and workforce. Baby Talk, a free prenatal education program, sought to address this growing need through a brief intervention for those with a positive screening. Baby Talk partnered with a local suicide prevention program to develop a tool to enhance access to care and to support emot [...]

240 713

Open Access Review

Neurotransmitters in the Modulation of Stress: A Bibliometric Mapping and Visual Analysis (2000–2023)

Received: 09 November 2025;  Published: 05 May 2026;  doi: 10.21926/obm.neurobiol.2602334

Abstract

Stress is a multifaceted response involving physiological, psychological, and behavioural processes, with neurotransmitters such as serotonin, dopamine, and norepinephrine playing key modulatory roles. This study aimed to map global research trends on stress and neurotransmitters, identify thematic clusters, and highlight emerging frontiers relevant to health and disease. A bibliometric analysis was conducted on 4,132 publications indexed in Scopus between 2000 and 2023. Data were retrieved and processed using Exce [...]

246 738

Open Access Research Article

Novel Bis-Quadridentate Pyrazolone-Based Ligands and Zinc(II) Complexes: Spectroscopic Characterization and In Vitro Anti-Malarial Activity

Received: 12 February 2026;  Published: 30 April 2026;  doi: 10.21926/rpse.2602007

Abstract

A new series of bis-quadridentate ligands (L1-L3) and their corresponding zinc(II) complexes (Complex 1-3) were rationally designed, synthesized, and characterized. The ligand framework features multiple donor sites that enable stable coordination to zinc(II), yielding well-defined metal complexes. The structures of the synthesized compounds were confirmed using a combination of analytical and spectroscopic techniques. Thermal gravimetric analysis revealed that all zinc complexes exhibit exceptional thermal stabili [...]

407 1055

Open Access Original Research

DWSIM-Based Process Simulation and Exergy Analysis of Bioethanol Production from Rice Husk

Received: 31 December 2025;  Published: 30 April 2026;  doi: 10.21926/aeer.2602008

Abstract

The growing concerns over fossil fuel dependency have motivated the exploration of sustainable biofuel alternatives. However, the practice of utilizing first-generation bioethanol production obtained majorly from food crops threat food supply market and poses threat to food security and land use. As a way forward, second-generation bioethanol from biomass, such as rice husk, an abundant agricultural residue, could potentially offer a promising pathway. Yet, its conversion remains energy-intensive and thermodynamica [...]

451 1287

Open Access Review

Exposure to Environmental Toxicants: Glymphatic System Dysfunction and Its Implications on Neurodevelopmental Disorders

Received: 30 October 2025;  Published: 27 April 2026;  doi: 10.21926/obm.neurobiol.2602333

Abstract

The glymphatic system is a glia-dependent network surrounding blood vessels that facilitates the exchange of cerebrospinal fluid (CSF) and interstitial fluid, playing a crucial role in clearing neuro-metabolites from the brain. This system’s efficiency in transporting waste significantly increases during non-rapid eye movement non-REM sleep. Recent findings suggests that malfunctioning of the glymphatic system might be linked to neurodevelopmental disorders such as attention-deficit/hyperactivity disorder (ADHD), a [...]

306 1081

Open Access Original Research

Cr(VI) Adsorptive Removal Using Raw Cordia africana Sawdust: Optimization of Operating Parameters, Kinetics, Isotherm, Thermodynamics, and Desorption Efficiency

Received: 04 January 2026;  Published: 24 April 2026;  doi: 10.21926/aeer.2602007

Abstract

Hexavalent chromium (Cr(VI)) is a carcinogenic pollutant commonly found in wastewater from tanning and electroplating industries. This study investigates the efficiency of raw Cordia africana sawdust as a biosorbent for Cr(VI) removal. Batch adsorption experiments were conducted by varying pH (3-8), contact time (10-120 min), and Cr(VI) concentration (21-47 mg/L) using Response Surface Methodology (RSM) with Box-Behnken design. Characterization was performed using FTIR, SEM, BET, pH, and PZC analysis before and aft [...]

258 926

Open Access Original Research

Early Stages of Low-Energy Pattern Formation in Ar Cluster Bombardment

Received: 04 March 2026;  Published: 24 April 2026;  doi: 10.21926/rpse.2602006

Abstract

Molecular dynamics is an essential tool for studying the formation of surface patterns in their early stages under low-energy bombardment. Recently, it has been shown that semiconductor surfaces such as Si can reorganize under ultra-low-energy conditions to form surface patterns. In this work, we investigate the formation of patterns on metal surfaces under these conditions. To accelerate the process, a longitudinal substrate model was employed, with clusters selected as projectiles. As is well known, pattern forma [...]

196 777

Open Access Original Research

Stochastic Assessment of Renewable Energy Reliability: A Case Study of North Euboea, Greece

Received: 20 December 2025;  Published: 20 April 2026;  doi: 10.21926/jept.2602008

Abstract

The increasing penetration of renewable energy sources (RES) in the energy mix, particularly solar photovoltaic and wind power, poses significant challenges to electricity grid reliability due to their inherent stochastic variability. This study develops a stochastic framework to assess the ability of RES to balance electricity demand, with a focus on storage requirements and reliability implications. Using North Euboea, Greece, as a representative case study, normalized hourly time series of electricity demand, so [...]

365 1580

Open Access Editorial

Athens 2026 – International Exchange of Professionals in Medicine: A Global Gala Technology Platform for Medical Sciences, Innovation, and Interdisciplinary Collaboration

Received: 19 April 2026;  Published: 20 April 2026;  doi: 10.21926/obm.icm.2602014

Abstract

The International Exchange of Professionals – Thematic Event in Medicine 2026, held in Athens, was a high-level interdisciplinary forum for clinical medicine, biomedical research, and translational innovation. Conducted at the Radisson Blu Park Hotel, the congress brought together more than 300 international experts from over 40 countries. It was organized under the auspices of the World High Technology Society in cooperation with BIT Group Global and the Shenzhen International Talent Exchange Center. The program i [...]

259 1204

Open Access Original Research

Exploring the Use of Plant Extracts from Leaves, Bark, and Roots of Boswelia dalzelia as Corrosion Inhibitors on Low-Carbon Steel Embedded in Concrete as Reinforcement When Subjected to Chloride and Acidic Environment

Received: 01 December 2025;  Published: 16 April 2026;  doi: 10.21926/rpse.2602005

Abstract

This study explores the use of plant extract to reduce corrosion on low-carbon steel reinforcement embedded in concrete. It is globally known that structures exposed to corrosive environments can collapse due to deterioration of the steel rods embedded in the concrete. The corrosion-inhibition potential of leaves, bark, and root extracts of Boswelia dalzelia (BD) on concrete reinforcement was investigated using a half-cell potentiometer and scanning electron microscopy (SEM) analysis. The half-cell potential readin [...]

190 773

Open Access Review

Climate Change-Induced Stress and Neural Plasticity: Genetic and Epigenetic Mechanisms of Adaptation

Received: 09 January 2026;  Published: 15 April 2026;  doi: 10.21926/obm.genet.2602337

Abstract

Changes in the environment driven by climate change are becoming significant stressors that impact brain function, but the connections between these changes and neural plasticity remain unclear. This review aims to offer a comprehensive synthesis of the impact of climate-related stressors on neural plasticity via genetic and epigenetic mechanisms. A structured literature search (2000-2025) was conducted using PubMed, Scopus, and Web of Science, integrating evidence from in vitro, animal, and human studies. Findings [...]

407 1843

Open Access Research Article

Development of New Macroencapsulating Planar Devices to Inhibit Allorejection of Islet Transformed Cells

Received: 31 August 2025;  Published: 14 April 2026;  doi: 10.21926/obm.transplant.2602269

Abstract

Subcutaneous transplantation of islets into small-pore macroencapsulation devices that prevent immune cell passage can inhibit allorejection in rodents. However, there are no reports of euglycemia in humans using this technology. This report further develops these macroencapsulation devices. We compared the ability of macroencapsulation transplant devices containing transformed mouse islet cells (MIN-6) with varying polymer membranes, pore sizes, and hydrophilicity to inhibit allorejection and maintain glycemic con [...]

253 1062

Open Access Case Report

A Novel Missense Variant in the CDH23 Gene is Segregated in an Iranian Family with Hearing Loss

Received: 25 November 2025;  Published: 13 April 2026;  doi: 10.21926/obm.genet.2602336

Abstract

Sensorineural hearing loss (SNHL) describes a diverse group of clinically and genetically distinct disorders of the auditory system. SNHL is associated with mutations in up to 150 genes. Among them is Cadherin 23 (CDH23), which is associated with both Usher syndrome and non-syndromic hearing loss. In the current study, we used WES to find the genetic cause of SNHL in an extended Iranian family. WES and subsequent Sanger sequencing confirmed the occurrence of a novel homozygote variant in the CDH23 gene (c.817T>C, p [...]

247 854

Open Access Case Report

A Case of Prenatal Diagnosis of Apert Syndrome in the Second Trimester of Pregnancy

Received: 12 September 2025;  Published: 13 April 2026;  doi: 10.21926/obm.genet.2602335

Abstract

Craniosynostosis is a disorder characterized by premature closure of cranial sutures, resulting in restricted skull growth perpendicular to the affected suture and compensatory growth in other directions. Over 180 syndromes have been classified under craniosynostosis, of which eight are associated with mutations in the fibroblast growth factor receptor 2 (FGFR2) gene: isolated coronal synostosis, Pfeiffer syndrome, Crouzon syndrome, Apert syndrome, Beare–Stevens syndrome, Jackson–Weiss syndrome, Crouzon syndrome wi [...]

242 806

Open Access Review

The Prevalence of Autism in the World: An Umbrella Review and Meta-Analysis

Received: 05 December 2025;  Published: 13 April 2026;  doi: 10.21926/obm.neurobiol.2602332

Abstract

Autism is a neurodevelopmental disorder characterized by persistent challenges in social interactions and repetitive behaviors. This study aimed to investigate the prevalence of autism and autism spectrum disorder(ASD) in normal and abnormal groups, such as premature infants or seizure patients, using an umbrella review and meta-analysis. This study was conducted in accordance with the PRISMA guidelines. Scientific sources included PubMed, Scopus, Web of Science, and Google Scholar, and searches were conducted with [...]

361 1467

Open Access Review

The Multi-Biophysical Nature of Computation in Brain Neural Networks

Received: 04 August 2025;  Published: 13 April 2026;  doi: 10.21926/obm.neurobiol.2602331

Abstract

Comprehending the nature of nerve communication is fundamental to our understanding of the functioning of nervous systems in general. The ionic mechanisms underlying action potentials in the squid giant axon were first described by Hodgkin and Huxley in 1952, and their findings have formed our orthodox view of how the physiological action potential functions. However, substantial evidence has now accumulated to show that the action potential is accompanied by a synchronized coupled soliton pressure pulse in the cel [...]

268 907

Open Access Original Research

Sustainable and Environmentally Friendly Approaches for Eliminating Alizarin Red S from Contaminated Water Using Hydroxyfluorapatite-Based Biomaterials

Received: 15 December 2025;  Published: 10 April 2026;  doi: 10.21926/aeer.2602006

Abstract

This study investigated the use of new bioadsorbent the Hydroxyfluorapatite (Ca10(PO4)6OH1.75F0.25, HFA) to eliminate Alizarin Red S (ARS), a harmful water pollutant. Initial batch tests were conducted to evaluate the adsorption process, focusing on both kinetics and equilibrium behavior. Various kinetic models were applied such as: pseudo first-order, pseudo second order, the intraparticular diffuision model and external diffusion model. The modeling results proved that the pseudo-second-order model best matched t [...]

356 1142

Open Access Review

Linking Brain, Hormones, and Metabolism: Pathophysiology and Treatment of Antipsychotic-Induced Cardiometabolic Side Effects

Received: 22 October 2025;  Published: 09 April 2026;  doi: 10.21926/obm.neurobiol.2602330

Abstract

This narrative review explores the pathophysiological consequences, neuroendocrine processes, and treatment approaches aimed at reducing the cardiometabolic adverse effects linked to antipsychotic medications; in particular, it highlights recent mechanistic advances in receptor-mediated metabolic dysregulation and emerging therapeutic implications. Schizophrenia, which is a long-term and debilitating disorder, correlates with a substantially shorter life expectancy (15-20 years less than that of the general populac [...]

848 2596

Open Access Original Research

Complete Chloroplast Genome of Rauvolfia tetraphylla (Gentianales: Apocynaceae) and Phylogenetic Analysis

Received: 15 January 2026;  Published: 07 April 2026;  doi: 10.21926/obm.genet.2602334

Abstract

Rauvolfia tetraphylla L. (1753) is an important medicinal species of Apocynaceae, widely used for its rich indole alkaloids and related bioactive compounds. We report the first complete chloroplast genome of R. tetraphylla. The genome exhibits a typical circular quadripartite structure of 155,667 bp, with an overall GC content of 37.8%. The genome comprises a large single-copy (LSC) region of 86,332 bp, a small single-copy (SSC) region of 17,853 bp, and a pair of inverted repeat (IR) regions of 25,741 bp each. A to [...]

372 1057

Open Access Review

Advances Toward In Vivo Cartilage Repair: A Comprehensive Review of Current Strategies and Future Directions

Received: 03 December 2025;  Published: 07 April 2026;  doi: 10.21926/rpm.2602003

Abstract

The cartilage is avascular and has limited regenerative capacity, posing a significant clinical challenge. Conventional treatments often do not restore hyaline cartilage, leading to progressive osteoarthritis. Recent advances in tissue engineering have focused on integrating biomaterials, stem cells, growth factors, and gene-delivery approaches. In addition, in vivo models serve as critical platforms for translational validation. Biomaterial scaffolds, including polycaprolactone, silk fibroin, chitosan, and composi [...]

512 3026

Open Access Research Article

A Qualitative Exploration: Black Women Living with Depression

Received: 14 September 2025;  Published: 07 April 2026;  doi: 10.21926/obm.icm.2602013

Abstract

Studies show Black women exhibit distinct depression symptoms and treatment experiences compared to other groups, often facing underdiagnosis and inadequate care. Unfortunately, knowledge about Black women with depression has been underexplored. Therefore, the purpose of this study is to gain a better understanding of Black women’s experiences living with clinical depression. To address this objective, we conducted a survey among 28 Black women aged 18 years and older (mean age = 35) residing in the United States, [...]

377 1188

Open Access Original Research

Photovoltaic Power Forecasting Without Local Data: A Spatially-Aware Approach Using Neighboring Plants

Received: 17 October 2025;  Published: 03 April 2026;  doi: 10.21926/jept.2602007

Abstract

The increasing demand for renewable energy sources has intensified the adoption of photovoltaic systems. This study proposes predictive models for solar power generation that operate without dependence on on-site meteorological stations. The proposed approach integrates generation data from geographically distributed plants and accounts for the distance to meteorological stations when constructing climatic variables. Two machine learning techniques, Random Forest (RF) and Long Short-Term Memory (LSTM) networks, wer [...]

343 1816

Open Access Review

Phytochemically Rich Food-System By-Products in Ruminant Diets: Nutritional and Health Benefits from Animals to Humans within a Circular Bioeconomy

Received: 10 December 2025;  Published: 03 April 2026;  doi: 10.21926/rpn.2602004

Abstract

Food-system by-products (FSBP), including agricultural by-products, agro-industrial co-products, and food-processing residues, represent an underused source of nutrients and plant secondary compounds with significant potential in ruminant feeding systems. This review synthesized 96 peer-reviewed studies published between 2000 and 2025 on phytochemically rich FSBP in ruminant diets, focusing on composition, rumen fermentation, animal health and performance, product quality, and environmental outcomes. Across the stu [...]

580 1842

Open Access Original Research

Comprehensive Cytogenetic and ISSR Analysis in the Context of Conservation of the Local Breed of Brown Carpathian Cattle Breed

Received: 01 December 2025;  Published: 01 April 2026;  doi: 10.21926/obm.genet.2602333

Abstract

The article reveals the variability of the genome of cattle of the local small-numbered domestic Brown Carpathian breed using cytogenetic and molecular genetic polylocus markers, and justifies the need to integrate local breeds into the modern system of agricultural production in accordance with FAO requirements. The work aimed to study the genetic uniqueness of cows of the brown Carpathian breed using cytogenetic and molecular genetic markers. The karyotype of the animals corresponded to the species norm and was 2 [...]

269 941

Open Access Original Research

Beyond the Feed: Academic, Emotional, and Social Consequences of Social Media Use Among College Students

Received: 22 October 2025;  Published: 30 March 2026;  doi: 10.21926/obm.icm.2601012

Abstract

In 2025, college students are reportedly more anxious and strained than any previous generation of young people, while they are also the first to have grown up entirely immersed in social media. This research explores social media use patterns and their relationship with academic, emotional, health-related and social well-being among college students. A total of 111 college students from an East Coast university self-selected to complete a one-time assessment anonymously through Qualtrics. A mixed-methods, explorat [...]

365 1595

Open Access Research Article

Central Post-Stroke Pain: Frequency, Clinical Characteristics, and Associated Factors

Received: 09 December 2025;  Published: 27 March 2026;  doi: 10.21926/obm.neurobiol.2601329

Abstract

Central post-stroke pain (CPSP) is a frequently underrecognized complication that contributes to long-term disability among stroke survivors. This study aimed to determine the frequency of CPSP and to describe its clinical characteristics and associated factors among stroke patients treated at Arifin Achmad General Hospital. A cross-sectional design was employed and included adult stroke patients with diagnoses confirmed by neuroimaging. CPSP was diagnosed based on the clinical criteria proposed by Klit et al., and [...]

263 1439

Open Access Original Research

Disability, Functional Limitations, and Family Violence among Older Adults in Brazil: A Cross-Sectional Study Using National Health Survey Data, Brazil 2019

Received: 12 September 2025;  Published: 27 March 2026;  doi: 10.21926/obm.geriatr.2601337

Abstract

Elder abuse is a global public health issue, with consequences on individual health, increased burden on healthcare systems, and high social costs. The study aimed to estimate the prevalence of family violence among older adults in Brazil and analyze its association with disability, comorbidities, functional limitation, and sociodemographic characteristics. Cross-sectional study using data from the 2019 National Health Survey (PNS 2019), including older adults aged 60 years or older. Bivariate and multiple logistic [...]

337 1071

Open Access Review

Integrated Evaluation of Electric Submersible Pump Failures under Diverse Field Operating Conditions

Received: 09 September 2024;  Published: 26 March 2026;  doi: 10.21926/jept.2601006

Abstract

Electrical submersible pumps (ESPs) are an efficient and reliable artificial lift method for lifting large volumes of fluids from wellbores at flexible rates. Despite their advantages, including high flow rates and real-time downhole telemetry, ESPs are prone to frequent and unforeseen failures under harsh reservoir conditions, resulting in costly production delays and interventions. This paper presents an integrated evaluation of ESP failure mechanisms based on an analysis of run and pull reports, dismantle inspec [...]

1048 2870

Open Access Review

Challenges and Ethical Issues Related to Non-Invasive Prenatal Testing (NIPT)

Received: 21 January 2026;  Published: 26 March 2026;  doi: 10.21926/obm.genet.2601332

Abstract

Non-invasive prenatal testing (NIPT) is now standard in prenatal care in many countries, even though it was introduced only about 15 years ago. Due to its rapid adoption into decades-old prenatal care plans, gynecologists, obstetricians, and the general public still struggle to understand the possibilities, benefits, and limitations of NIPT. The biggest challenge facing NIPT is that comprehensive training for healthcare professionals and independent, unbiased information for pregnant women and their families about [...]

627 2279

Open Access Original Research

Assessment of Genetic Diversity and Polymorphism in Corylus avellana L. Pollen by Inter-Primer Binding Site Marker Analysis

Received: 26 December 2025;  Published: 23 March 2026;  doi: 10.21926/obm.genet.2601331

Abstract

Genetically conditioned variation in pollen has been demonstrated to have a substantial influence on reproductive mechanisms and population dynamics. The present study evaluated the genetic variability of 28 pollen samples of Corylus avellana L. using iPBS (Inter Primer Binding Sites Polymorphism) markers 1882 and 2152. The collection of biological material was undertaken at various locations across five European countries, with the objective of capturing a broad spectrum of environmental conditions. The genetic re [...]

316 1042

Open Access Original Research

Development of Methods for Transplanting Human Islet within Macroencapsulation Device that Reverse Diabetes in Mice

Received: 09 October 2025;  Published: 20 March 2026;  doi: 10.21926/obm.transplant.2601268

Abstract

Transplanting islets into the subcutaneous (SC) space rather than the portal vein is advantageous because this site is easier and safer to use. However, transplantation of islets directly or within planar devices has been unsuccessful in humans, mainly because of the low oxygen torr in the SC space. Since human islets are very different from mouse islets, the use of human islets in animal experiments to study SC islet transplantation may help to alleviate the roadblocks of this approach in humans. This is the first [...]

334 1460

Open Access Original Research

Evaluation of Ten Bread Wheat (Triticum aestivum) Cultivars and Five of Their Hybrids under Salinity Stress at Germination and Seedling Stage

Received: 23 November 2025;  Published: 20 March 2026;  doi: 10.21926/obm.genet.2601330

Abstract

Salinity poses a danger to food security; hence, it is necessary to create crop types that can withstand salt to meet the growing demand for food. The goal of the current study was to examine the morphological and biochemical responses of wheat (Triticum aestivum L.) genotypes under salt stress. Salt tolerance in ten wheat cultivars and five selected F1 hybrids was assessed at the germination and seedling stage. Genotypes were assessed for seven traits under control (0 mM NaCl) and salinity stress (150, 200, and 25 [...]

298 1156

Open Access Original Research

A New Model for the Shear of Atomic Planes

Received: 21 December 2025;  Published: 18 March 2026;  doi: 10.21926/rpm.2601002

Abstract

The article presents a model that describes the shear of atomic planes in crystalline solids by accounting for their electronic structure. Previous studies have shown that an isotropic distribution of valence electrons leads to a spherically symmetric interatomic potential, which affects the stability of the crystal lattice against small shear deformations. Under these conditions, lattice stability is largely determined by the crystal's surface layer. As a consequence, the resistance to atomic-plane shear exhibits [...]

392 1346

Open Access Review

Insights from Stem Cell and CRISPR-Based Therapies for Diabetes Mellitus: A Systematic Review

Received: 27 November 2025;  Published: 17 March 2026;  doi: 10.21926/obm.genet.2601329

Abstract

Diabetes mellitus (DM) is a metabolic disorder resulting from aberrations in insulin secretion or action. Diabetes mellitus still presents as a global health challenge. Conventional diabetes treatment may result in unwanted side effects and/or poor compliance. More personalized and curative approaches to the treatment of DM are required. The review explores recent developments in the fields of genetic and molecular underpinnings of DM, focusing on the revolutionary potential of cell- and Clustered Regularly Intersp [...]

842 3746

Open Access Original Research

Determining the Role of KRAS in Patients with Different Demographic Profiles Diagnosed with Diabetes Mellitus: A Case-Control Study

Received: 06 December 2025;  Published: 15 March 2026;  doi: 10.21926/obm.genet.2601328

Abstract

Diabetes mellitus (DM) is widely spread among populations. About 3 of 10 people show the symptoms of this disease. Many factors may cause this illness in both types (type 1 and type 2 DM), mainly attributed to insufficient insulin production in type 1 DM or developing insulin resistance in type 2 DM. Genes that control specific biochemical pathways involving glucose metabolism can interfere with the manifestation of this disease when they undergo genetic changes like KRAS. Investigating the role of KRAS in DM. Abou [...]

315 1015

Open Access Research Article

“Make Sure That Our Culture and Color is Known:” Maternal Perceptions of Using Media in the Ethnic-Racial Socialization of Young Black Children

Received: 10 October 2025;  Published: 13 March 2026;  doi: 10.21926/obm.icm.2601011

Abstract

Although methods of ethnic-racial socialization have been studied in the past, welcoming in a new digital age has affected how parents engage with their children on topics such as race and culture. While media can be an engaging way to expose young children to race and culture, the underrepresentation of Black youth in media in the United States has posed a dilemma for Black parents about the best way of using media to socialize their young children. To understand how Black mothers expose their children to ideas ab [...]

435 1430

Open Access Original Research

A Rapid Method of Examining Land Use/Land Cover at Small Industrial Facilities Using Four U.S. Department of Energy Sites as Case Studies

Received: 26 September 2025;  Published: 13 March 2026;  doi: 10.21926/rpse.2601004

Abstract

This work addresses the application of a method to examine the spatial extent of ecological resources and green space on small Department of Energy (DOE) sites and comparison to ecological resources and green space in the surrounding region. Increasingly, governmental regulators, resource trustees, and the public are concerned that federal facilities are protecting human health and the environment, including ecological resources on their sites. This paper uses the National Land Cover/Land Use Database to examine an [...]

338 1121

Open Access Original Research

End-of-Life Care Disparities in Older Adults with Schizophrenia Spectrum Disorders

Received: 14 October 2025;  Published: 10 March 2026;  doi: 10.21926/obm.geriatr.2601336

Abstract

Schizophrenia spectrum disorders (SSDs) are complex conditions with chronic symptoms and impairments associated with greater risk for physical comorbidity and early mortality. Understanding end-of-life care in older adults with SSDs is crucial for improving geriatric psychiatric care and identifying healthcare disparities. A cohort of 254 older adult decedents with a history of schizophrenia or schizoaffective disorder was identified using the Rochester Epidemiology Project. A control group of 254 older adult deced [...]

600 1654

Open Access Original Research

Image Generation Inspired by Electroencephalography for Neuromarketing Applications Using Extracted Features from Transformer-Based Models

Received: 25 September 2025;  Published: 10 March 2026;  doi: 10.21926/obm.neurobiol.2601328

Abstract

The design of products in Neuromarketing using machine learning methods has been a continuous challenge in Computer-aided design. Previously, deep learning techniques have been applied to generate random images for domains such as furniture, fashion, and product design. However, using deep generative methods requires a large amount of data and overlooks human aspects in the design process. This paper aims to extract human perceptual factors from brain signals using a Transformer-based model and involve them in arti [...]

513 1678

Open Access Research Article

Modelling and Optimisation of Integrated Renewable Energy Conversion Technologies with Dual Energy Storage for an Island

Received: 17 September 2025;  Published: 09 March 2026;  doi: 10.21926/jept.2601005

Abstract

The work focused on modelling and optimisation of integrated renewable energy conversion technologies based on sunlight, wind, and biomass, with dual energy storage (battery and hydrogen), for Patani Island, Delta State, Nigeria. The study was aimed at satisfying the energy demand of the Patani Island community (5°13’43” N, 6°11’29” E). A mathematical model was developed to describe the integrated system, and a genetic algorithm was employed to optimize the allocation of energy demand, energy generation, and energy [...]

445 1471

Open Access Original Research

Investigating Interfacial Thermal Resistance and Effective Thermal Conductivity in Epoxidized Natural Rubber Composites

Received: 14 January 2026;  Published: 09 March 2026;  doi: 10.21926/rpse.2601003

Abstract

Effective thermal management in polymeric materials still represents a considerable challenge for emerging applications, such as wearable electronics, soft robotics, and sustainable composite systems, wherein flexibility and environmental compatibility are of utmost importance. This research utilizes non-equilibrium molecular dynamics (NEMD) simulations to examine interfacial thermal resistance (ITR) and effective thermal conductivity (keff) in bio-based PBS-ENR-PBS trilayer systems. Two varieties of epoxidized nat [...]

634 2793

Open Access Review

Unraveling the Role of Non-Coding Genetic Variants in Male Infertility: Insights from the Chinese Population

Received: 03 December 2025;  Published: 09 March 2026;  doi: 10.21926/obm.genet.2601327

Abstract

Male infertility is a growing concern worldwide, with almost half of infertility cases being male, and the trend is rising in China as a result of multifaceted genetics-environment interaction. Important breakthroughs have been made in identifying mutations in annotated protein-coding genes associated with male infertility. However, a significant part of the human genome, namely non-coding DNA, has not yet been explored. Recent breakthroughs in the realm of high-throughput genomic technologies have unveiled the ind [...]

398 1432

Open Access Research Article

Embodied Rituals and Healing Practices in Turkish Health Culture: Implications for Contemporary Healthcare Environments

Received: 14 October 2025;  Published: 02 March 2026;  doi: 10.21926/obm.icm.2601010

Abstract

Throughout human history, movement has functioned not only as a physical activity but also as a ritual, considered a healing practice linked to meaning-making and social balance. Bodily performances and ritual-based practices—such as folk dances and mystical rituals—have historically supported the physical and emotional integrity of individuals. This paper examines the historical continuity of movement-based performative practices in Turkish health culture through religious and mystical rituals, folk dances, and mu [...]

526 1771

Open Access Original Research

Restoring the Resilience of Water-Energy-Food Nexus Based on Desalination through Biomass Management: Case Study West Mani, Greece

Received: 03 November 2025;  Published: 01 March 2026;  doi: 10.21926/aeer.2601005

Abstract

Mediterranean regions like West Mani, Greece, face escalating water scarcity exacerbated by climate variability and seasonal tourism peaks, straining the water-energy-food (WEF) nexus. Olive cultivation, central to the region’s economy and culture, generates substantial underutilized biomass residues that increase wildfire risk if left unmanaged. At the same time, water supply increasingly relies on energy-intensive desalination and pumping. This study addresses the gap in integrated, place-based WEF nexus applicat [...]

774 2770

Open Access Review

Migraine Surgery: Assessment of the Prevalence and Surgical Outcomes of Different Trigger Sites

Received: 14 November 2025;  Published: 28 February 2026;  doi: 10.21926/obm.neurobiol.2601327

Abstract

Migraine surgery is primarily indicated for patients with chronic migraine who are refractory to conventional pharmacological treatments. The procedure aims to deactivate peripheral trigger sites—anatomical zones where migraines can be triggered by nerve compression and irritation. The most common trigger areas are the frontal, occipital, and temporal. This review seeks to analyse the prevalence of treatment and corresponding success rates for these three main trigger sites. A systematic review was conducted on Pub [...]

454 1800

Open Access Original Research

Quasi-Solid-State Electrolytes of Polyethylene Oxide-Based Composite Electrolyte with Liquid Electrolytes

Received: 18 November 2025;  Published: 26 February 2026;  doi: 10.21926/jept.2601004

Abstract

A thin film of PEO18Li(CF3SO2)2N(LiTFSI)-tetraethylene glycol dimethyl ether (G4)-Li1.4Al0.4Ge0.2Ti1.4(PO4)3-LiCl·H2O (LAGTP·LiCl) was prepared by addition of 1,2-dimethoxyethane (DME). The grain boundary resistance of PEO18LiTFSI-LAGTP·LiCl was considerably reduced by the addition of G4, and a large-sized thin film of the composite polymer electrolyte was prepared easily by the addition of 10 wt.% DME. The electrical conductivity of [(PEO18LiTFSI-2G4)-5 wt.% LAGTP·LiCl]-10 wt.% DME was 1.2 × 10-4 S cm-1 at 25°C, a [...]

615 1674

Open Access Original Research

Aversion But Not Aggression: Emotional Traits of KM Rats in Sociability Tests

Received: 28 September 2025;  Published: 25 February 2026;  doi: 10.21926/obm.neurobiol.2601326

Abstract

The inbred Krushinsky-Molodkina (KM) rat strain, characterized by latent genetic epilepsy, reduced social motivation, and a high propensity for freezing, is a promising model for translational research of social deficits in autism spectrum disorder (ASD). In clinical practice, social deficits often lead to social withdrawal and can be accompanied by aggression. It was unknown if KM rats exhibit such aggression during inescapable social encounters. We assessed intraspecific aggression in KM and control rats using th [...]

476 1329

Open Access Original Research

Examining the Pre-Hospital Workflow of Stroke Patients Referred with Code SAMA (724) and their Outcome in the Emergency Department of Imam Reza Hospital (AS)

Received: 22 February 2025;  Published: 25 February 2026;  doi: 10.21926/obm.neurobiol.2601325

Abstract

The "Sama Code" is a protocol implemented in Iranian pre-hospital emergency services to manage time and treat patients with suspected stroke symptoms based on the FAST criteria. This study aims to analyze the workflow of patients with stroke symptoms transferred under the Sama Code. All patients with neurological symptoms who were brought to Imam Reza Hospital by pre-hospital emergency services after activating the Sama Code during the years 2021 and 2022 were included in the study. Data were collected from pre-hos [...]

429 1262

Open Access Review

Novel Therapies for the Treatment of Antibody Mediated Rejection in Solid Organ Transplantation: A Systematic Review

Received: 29 October 2025;  Published: 24 February 2026;  doi: 10.21926/obm.transplant.2601267

Abstract

Antibody mediated rejection (AMR) is a considerable cause of late allograft failure in solid organ transplantation. Conventional approaches, using plasmapheresis, intravenous immunoglobulin, rituximab, bortezomib, and eculizumab have been unsuccessful in improving graft survival. This review aims to assess emerging therapies for AMR treatment across all organs. Using a PubMed search, literature published up to July 20, 2025 regarding tocilizumab, clazakizumab, carfilzomib, daratumumab, imlifidase, felzartamab, and [...]

653 3139

Open Access Original Research

Hydroclimatic Variability and Precipitation Extremes in Sindh under a Changing Climate

Received: 12 August 2025;  Published: 24 February 2026;  doi: 10.21926/aeer.2601004

Abstract

Sindh Province, Pakistan, is highly vulnerable to hydroclimatic extremes, necessitating a detailed understanding of its precipitation patterns for effective water management. This study assesses spatiotemporal precipitation dynamics across Sindh from 2001 to 2024 by integrating satellite-based CHIRPS data, in situ observations from the Climate Knowledge Portal (CKP), and CMIP6 climate model projections. Validation results show strong agreement between CHIRPS and ground data (R ≈ 0.87, d ≈ 0.93), confirming the sate [...]

699 2343

Open Access Review

Red Meat Consumption and Rheumatic Diseases: A Comprehensive Narrative Review

Received: 03 November 2025;  Published: 23 February 2026;  doi: 10.21926/rpn.2601003

Abstract

Dietary factors influence chronic inflammation and immune regulation, potentially affecting the onset and activity of rheumatic disease. Red meat, a major source of protein, heme iron, and saturated fat, has been linked to metabolic and inflammatory disorders, yet its role in rheumatic diseases remains unclear. To comprehensively evaluate the relationship between red-meat consumption and major rheumatic diseases—including rheumatoid arthritis (RA), gout, systemic lupus erythematosus (SLE), and other inflammatory or [...]

1289 3648

Open Access Review

Selenium Supplementation in Rheumatoid Arthritis: Evidence from Controlled Clinical Trials and Mechanistic Insights

Received: 27 October 2025;  Published: 13 February 2026;  doi: 10.21926/rpn.2601002

Abstract

Selenium (Se) is a key micronutrient integrated into selenoproteins such as glutathione peroxidases (GPx), which are responsible for crucial antioxidant and anti-inflammatory mechanisms. Oxidative stress contributes to the immunopathogenesis and chronic joint damage of rheumatoid arthritis (RA), supporting interest in selenium supplementation as an adjunct therapeutic strategy. This review was based on a structured literature search of major biomedical databases and evaluated six controlled clinical trials involvin [...]

1074 3043

Open Access Original Research

Wind Turbine Tower Structural and Cost Optimisation within Acceptable Structural Integrity

Received: 26 June 2025;  Published: 13 February 2026;  doi: 10.21926/jept.2601003

Abstract

As the demand for cleaner-greener energy surges owing to more nations adopting Net Zero Emission by 2050, wind turbine (WT) technology is increasingly poised as one of the technologies to match the demand. Capacity building in the development of cost-effective WT tower with improved reliability and safety has become critical to delivering Net Zero mandate. This research demonstrates implementation of Taguchi Design of Experiment (DoE) in conjunction with Signal-to-noise ratio (S/N) to optimise both structural desig [...]

798 2885

Open Access Original Research

Compassionate Mind Training for All: An Evaluation of a One-Day Compassionate Mind Training Workshop for Mental Health NHS Staff as Part of Compassion Focused Staff Support

Received: 13 October 2025;  Published: 13 February 2026;  doi: 10.21926/obm.icm.2601009

Abstract

It has become increasingly evident that individuals who work in the NHS can be heavily impacted by the nature of their work; for instance, PTSD, work related burnout, vicarious trauma, moral injury, anxiety, and depression. In turn, individuals who experience said psychological difficulties often require work-related mental health leave from work. This paper examines the experience of a One-day Compassionate Mind Training workshop (CMT), available for all NHS staff. This day has an emphasis on developing multidirec [...]

772 2394

Open Access Original Research

Photocatalytic and Catalytic Methods for Organic Azo Dyes and Paranitrophenol Pollutants Removal Using Green Synthesised Flacourtia indica Silver Nanoparticles

Received: 30 October 2025;  Published: 12 February 2026;  doi: 10.21926/cr.2601004

Abstract

The advancement of photocatalytic nanomaterials has become central to addressing the growing challenge of removing organic pollutants from water systems through sustainable and efficient degradation pathways. In this study, silver nanoparticles were synthesized via a green approach using aqueous extracts derived from five parts of Flacourtia indica, including bark, flower, fruit, seed, and leaves, at 90°C for 45 minutes. UV–VIS spectroscopy (460 nm) confirmed nanoparticle formation, while scanning electron microsco [...]

871 2259

Open Access Editorial

Nutrition and Transplant Outcomes

Received: 27 January 2026;  Published: 12 February 2026;  doi: 10.21926/obm.transplant.2601266

Abstract

Dietary guidelines and Nutrient Reference Intakes are important tools for maintaining optimal health in the general population. Similar guidelines have also been developed by specific organ health associations to help their patient populations recover from disorders or prevent/delay clinical events and subsequent complications. However, there are no specific national and international guidelines to provide dietary and nutrient intake recommendations peri-transplantation. The complex nature of transplantation and in [...]

572 1358

Open Access Original Research

The Impact of Governmental and Workplace Measures on the Employment Sustainability of Chronically Ill Individuals

Received: 03 November 2025;  Published: 12 February 2026;  doi: 10.21926/obm.neurobiol.2601324

Abstract

Using a two-stage qualitative design (Stage 1: expert interviews; Stage 2: biographical interviews with people with MS), existing governmental and organizational support measures for maintaining the work capacity of individuals with multiple sclerosis (MS) were analyzed, and proposals for improvement were developed. Additional state support measures were proposed, including relaxing the criteria for state assistance, creating a centralized contact point for MS-specific inquiries, and enhancing collaboration between [...]

458 1220

Open Access Original Research

Chemical Composition, Antioxidant Properties, and Nutritional Value of Diospyros kaki L. as a Potential Functional Food

Received: 10 November 2025;  Published: 12 February 2026;  doi: 10.21926/obm.icm.2601008

Abstract

Persimmon (Diospyros kaki L.) is increasingly recognized as a nutrient-dense fruit rich in health-promoting compounds. This study aimed to comprehensively evaluate the nutritional composition, phenolic profile, antioxidant potential, and elemental content of D. kaki fruit and its contribution to dietary mineral intake. Proximate analysis revealed a high moisture content, low fat, and appreciable fiber and carbohydrate levels, supporting its classification as a low-calorie, fiber-rich food. Methanolic extracts exhib [...]

767 2170

Open Access Original Research

Sexuality in Older Adults Receiving Palliative Care: A Fundamental Dimension through the End of Life

Received: 08 October 2025;  Published: 11 February 2026;  doi: 10.21926/obm.geriatr.2601335

Abstract

The sexuality of older adults at advanced stages of illness, or at the end of life, remains a taboo topic that is rarely addressed in the literature and in practice. As a result, the knowledge base informing the support needs of older adults at the final stages of life with regards to sexuality remains scant. The present study seeks to explore experiences of sexuality in older adults with serious illness or receiving palliative care, focusing specifically on the place of sexuality in their lives, the forms of sexua [...]

588 1932

Open Access Original Research

Characterization of Drought Severity Using GRACE and TerraClimate Dataset in the Rift Valley Basin, Ethiopia

Received: 08 November 2025;  Published: 10 February 2026;  doi: 10.21926/aeer.2601003

Abstract

Characterizing drought severity using GRACE and TerraClimate datasets is globally important because it enables consistent, large-scale monitoring of both surface and subsurface water availability across data-scarce regions. This integrated perspective supports improved drought assessment, climate change impact analysis, and informed water-resource management worldwide. The Ethiopian Rift Valley has experienced recurrent hydrological drought hazards, posing serious threats to water availability, agricultural product [...]

844 2539

Open Access Review

Advancing Mathematical Learning in Children and Adolescents with Autism Spectrum Disorder through Serious Games and Educational Robotics: A Mini Review

Received: 04 November 2025;  Published: 10 February 2026;  doi: 10.21926/obm.neurobiol.2601323

Abstract

Mathematical learning often presents persistent challenges for children and adolescents with Autism Spectrum Disorder (ASD) due to differences in Executive Functioning (EF), cognitive flexibility, and symbolic reasoning. These factors can hinder the development of numerical understanding and pre-mathematical reasoning, problem-solving, and abstract thinking, frequently resulting in disengagement and anxiety. In recent years, digital and embodied technologies—particularly Serious Games (SG) and Educational Robotics [...]

936 3151

Open Access Review

Exposure to Mycotoxins: Neurological Disorders and Psychiatric Manifestations

Received: 27 October 2025;  Published: 09 February 2026;  doi: 10.21926/obm.neurobiol.2601322

Abstract

Mycotoxins, toxic secondary metabolites produced by fungi and molds, have negative health impacts on both humans and animals. They are commonly found in foods such as nuts, coffee, cereals, and grains, particularly in regions with warm, humid climates. Among the most prevalent mycotoxins in these foods are aflatoxin B1, ochratoxin A, zearalenone, patulin, and deoxynivalenol (DON). The presence of mold capable of producing mycotoxins within food contributes to an elevated risk of various illnesses, including those r [...]

1628 6424

Open Access Original Research

Impaired Cognitive Performance and Driving: A Comparative Study of Older Adults and Younger Adult Drug Users

Received: 02 September 2025;  Published: 05 February 2026;  doi: 10.21926/obm.geriatr.2601334

Abstract

Driving is a complex cognitive behavior that is an essential part of everyday life and can be broken down into many subcomponents. Due to aging and medication interactions, a wide range of motor, sensory, and cognitive skills that are imperative for driving are affected in older adults. Several studies show that the number of crashes and mortality rates increase by age and the consumption of cannabis and cocaine is associated with a range of adverse mental and physical effects. The purpose of this study was to iden [...]

864 2062

Open Access Research Article

Transformational Spaces: An Interpretative Phenomenological Inquiry into the Lived Experience of Young People Visiting Kanha Shanti Vanam Meditation Center, Telangana, India

Received: 29 October 2025;  Published: 04 February 2026;  doi: 10.21926/obm.icm.2601007

Abstract

The innate desire to belong and to connect is profoundly human, yet in a world of instant communication, millions of young people increasingly feel untethered and adrift. Loneliness is the 21st century's primary health care concern across all age groups. Young people not only feel lonely and emotionally isolated, but they also describe a lack of meaningful connections and purpose. Young people lack safe spaces where they can connect with their peers, without fear of judgment, prejudice, and pressure to succeed. In [...]

583 1787

Open Access Original Research

Analysis of Leukocyte Telomere Length in Brazilian People Living with HIV with and Without Cancer

Received: 31 May 2025;  Published: 04 February 2026;  doi: 10.21926/obm.genet.2601326

Abstract

Advances in antiretroviral therapy (ART) have normalized the life expectancy of people living with HIV (PLWH) but have been linked to a premature presentation of age-related comorbidities, including cancer. Telomere length (TL) is a marker of cellular aging and was investigated in blood leukocytes from 78 PLWH on ART, compared with 163 HIV-uninfected controls. The PLWH group was stratified into three subgroups: HIV-only (n = 57), HIV with AIDS-defining cancer (ADC, n = 9), and HIV with NADC (n = 12). Quantitative p [...]

669 1538

Open Access Research Article

On the Prediction of Spur Gear Maintainability in Bottling Machines based on Failure Data

Received: 27 October 2025;  Published: 02 February 2026;  doi: 10.21926/rpse.2601002

Abstract

In bottling companies, spur gears play a vital role in ensuring efficient mechanical power transmission in bottling machines. Therefore, the maintainability of spur gears in these machines is important because it directly affects the overall efficiency, productivity, and cost-effectiveness of bottling operations. The study focused on data collection for different tasks performed on a failed gear from January to December of a particular year based on task time and frequency of occurrence, which are important factors [...]

550 1610

Open Access Commentary

Targeting Neuroinflammation in Difficult-to-Treat Depression: From Anti-Inflammatory Agents to Multi-Target Immunopsychiatric Interventions

Received: 30 July 2025;  Published: 27 January 2026;  doi: 10.21926/obm.neurobiol.2601321

Abstract

Difficult-to-treat depression (DTD) with inflammatory features (e.g., hs-CRP ≥3 mg/L and/or elevated IL-6) may represent a clinically and biologically distinct presentation characterized by chronicity, functional impairment, prominent cognitive-motivational symptoms, and suboptimal response to conventional treatments. Classical anti-inflammatory strategies (e.g., COX-2 inhibitors or cytokine-targeting biologics) have shown signals of efficacy in selected biomarker-enriched subgroups; however, overall evidence remai [...]

1093 3232

Open Access Perspective

Optimizing Psychopharmacotherapy Using Personality Biomarkers: A Seven-Factor Model Perspective

Received: 19 September 2025;  Published: 26 January 2026;  doi: 10.21926/obm.neurobiol.2601320

Abstract

Personalized psychopharmacotherapy remains a critical yet underdeveloped frontier in psychiatry, as traditional approaches often fail to address substantial interindividual variability in drug efficacy and tolerability. While demographic, clinical, and genetic factors have improved treatment precision, they do not fully account for observed heterogeneity. Recent advances highlight the promise of personality traits, particularly as operationalized by Cloninger’s Seven-Factor Model, as novel biomarkers for treatment [...]

702 1973

Open Access Original Research

Promising Electrocatalytic Systems 2,5-di-Me-Pyrazine-di-N-Oxide - Cyclohexanol - Single-Walled and Multi-Walled Carbon Nanotubes for the Simultaneous Metal-Free Oxidation of Cyclohexanol at Anode and Release of Hydrogen Evolution at Cathode

Received: 07 August 2025;  Published: 26 January 2026;  doi: 10.21926/cr.2601003

Abstract

Electrocatalytic oxidation of organic compound in the absence of noble metals or their oxides as catalysts and using metal-free electrodes is a "green" electrochemical, inexpensive and attractive process for practical use in electrocatalysis, power sources and sensors. The process accompanied by the elimination of protons, is of interest both for obtaining valuable organic compounds at the anode and for the release of hydrogen evolution at the cathode. In this work, the catalytic oxidation of cyclohexanol in the pr [...]

633 1575

Open Access Concept Paper

Movement-informed Breathwork (MiB): Integrating Muscular Contractions with Slow Conscious Connected Breathing for Therapeutic Application

Received: 28 July 2025;  Published: 22 January 2026;  doi: 10.21926/obm.icm.2601006

Abstract

This paper introduces Movement-informed Breathwork (MiB), a personalised breath-body approach with biofeedback that integrates a form of conscious connected breathwork (breathing without pauses) with targeted neuromuscular contraction and relaxation cycles. Drawing from neuromuscular torque chain dynamics, fascial research and sensorimotor trauma therapy principles, MiB aims to enhance autonomic regulation, interoceptive awareness and somatic-emotional integration by bridging traditional breathwork (deep, slow-pace [...]

1223 4462

Open Access Review

Balancing Preservation and Maximizing Utilization: A DCD Lung Procurement Strategy During Abdominal Normothermic Regional Perfusion

Received: 30 June 2025;  Published: 22 January 2026;  doi: 10.21926/obm.transplant.2601265

Abstract

The increasing demand for organ transplantation has necessitated innovative strategies to maximize donor organ utilization, especially in donation after circulatory death (DCD) contexts. This article explores the integration of direct lung recovery with abdominal normothermic regional perfusion (A-NRP) to optimize organ preservation and expand the donor pool. A-NRP effectively mitigates warm ischemic injury, supporting the viability of both abdominal and thoracic organs. Our approach emphasizes meticulous surgical [...]

612 2181

Open Access Original Research

Evidence for an Impact of Super Skills for Life on Emotional and Behavioral Difficulties in Greek Anxious Children

Received: 23 September 2025;  Published: 22 January 2026;  doi: 10.21926/obm.neurobiol.2601319

Abstract

Super Skills for Life (SSL) is a transdiagnostic psychoeducational program designed for children with anxiety and depressive symptoms based on cognitive-behavioral therapy. Empirically documented studies to date have demonstrated its immediate and long-term effectiveness in different contexts. The aim of this study was to assess the efficacy of the SSL program to reduce emotional and behavioral difficulties in a clinical sample of Greek-speaking primary school children aged 6 to 12. The program was implemented over [...]

577 1980

Open Access Review

Machine Perfusion in DCD Lung Transplantation: Advances in Preservation and Donor Pool Expansion

Received: 30 June 2025;  Published: 21 January 2026;  doi: 10.21926/obm.transplant.2601264

Abstract

To address the pressing shortage of donor lungs, Donation after Circulatory Death (DCD) transplantation has become a vital strategy for expanding the donor pool. Minimizing warm ischemic injury is crucial for optimizing organ viability and function. This review synthesizes current evidence on Normothermic Regional Perfusion (NRP) and Ex-Vivo Lung Perfusion (EVLP) in DCD lung transplantation. Analysis reveals their growing efficacy in minimizing ischemic damage, facilitating organ assessment, and expanding the trans [...]

730 3005

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