by Marcus A. Henning  , Tae Joo Park  , Fiona Moir  , Chris Krägeloh  , Christopher Mysko  , Jennifer Hobson  and Craig S. Webster

Received: 25 May 2018;  Published: 26 October 2018;  doi: 10.21926/obm.icm.1804027

Background: The purpose of this systematic review was to appraise the empirical evidence pertaining to medical students and the integration of mindfulness and physical exercise regimens. Methods: A systematic review was undertaken. Five databases were used to survey the salient literature. Results: The initial search identified 353 potentially relevant articles of which 17 articles were considered for the final review. The findings indicated that the research was mainly conducted in the USA with some research origi [...]

by Pei-Yu Wu  , Kristina Mjörnell  , Claes Sandels  and Mikael Mangold

Received: 22 January 2021;  Published: 11 May 2021;  doi: 10.21926/rpm.2102017

Assessment of the presence of hazardous materials in buildings is essential for improving material recyclability, increasing working safety, and lowering the risk of unforeseen cost and delay in demolition. In light of these aspects, machine learning has been viewed as a promising approach to complement environmental investigations and quantify the risk of finding hazardous materials in buildings. In view of the increasing number of related studies, this article aims to review the research status of hazardous mater [...]

by Angelo Morro

Received: 19 February 2021;  Published: 13 April 2021;  doi: 10.21926/rpm.2102011

The objective of the paper is twofold: first, to review the classical diffusion models and show the approximations at the origin of the parabolic character of the classical equations; second, to demonstrate a connection between the quantum and classical models of diffusion. As diffusion is inherently related to the motion of constituents, the consistent models are framed within the dynamics of mixtures. The derivation of diffusion equations is then determined based on the related, pertinent approximations.

by Joseph V. Pergolizzi  , Aaron Tabor  , Jo Ann LeQuang  , Michael Annabi  and Hani Annabi

Received: 05 June 2019;  Published: 05 November 2019;  doi: 10.21926/obm.icm.1904062

Background: The ketogenic diet (KD) was developed in the 1920s as a treatment for pediatric epilepsy and is emerging as a possible treatment option for certain mental health disorders. There is a link between certain mental health disorders and epilepsy, suggesting some commonality among underlying mechanisms. Methods: The literature relating to mental disorders and the KD is sparse. The authors attempt to a narrative review of the existing literature to show that there may be validity to studying the KD as a treat [...]

by Kiril Fedorov  , Sonia Sheikh  , Alex Romaschin  and Michael Thompson

Received: 03 May 2020;  Published: 18 August 2020;  doi: 10.21926/rpm.2003019

During a variety of medical procedures such as renal dialysis, bypass surgery, and lung transplantation patient blood is exposed to the surface of a number of polymeric materials such as polycarbonate (PC), poly (vinyl chloride) (PVC) and polysulfone (PS) for a period up to several days. Such exposure may result in undesirable protein-material interactions that can potentially trigger deleterious biological processes including thrombosis, which may be responsible for other complications such as cognitive disability [...]

by Sima Farpour  , David Smithard  and Hamid reza Farpour

Received: 14 November 2019;  Published: 20 February 2020;  doi: 10.21926/obm.geriatr.2001109

Dysphagia is a term that is used for the difficulty in moving liquid/food from mouth to the stomach. Dysphagia is very common in elders, which makes them susceptible to malnutrition, infection, institutionalization, and death. Consequently, it is categorized as a geriatric syndrome. Therefore, multidisciplinary teams need to work together to determine the correct etiology and implement an appropriate care plan. Oral care is crucial in managing dysphagia and dental hygienists and dentists serve as the key members. I [...]

by Ganisetti Vijay Kumar  , Min-Ze Lu  and Chang-Ming Liaw

Received: 19 December 2020;  Published: 31 May 2021;  doi: 10.21926/jept.2102023

This paper presents the development of a high-performance electric vehicle (EV) synchronous reluctance motor (SynRM) drive and its vehicle-to-grid (V2G) and vehicle-to-microgrid (V2M) bidirectional operations. The EV motor drive boostable DC-link voltage is established by a battery through a bilateral interface boost-buck DC-DC converter for good driving performance over a wide speed range. The motor efficiency is 92.3% near the rated load. In idle conditions, the embedded interface converter and inverter of the mo [...]

by Karine Sénécal  , Brigid Unim  and Bartha Maria Knoppers

Received: 19 October 2017;  Published: 14 August 2018;  doi: 10.21926/obm.genet.1803027

The benefits of neonatal screening programs are undeniable: children’s lives are saved, and disease burden and morbidity alleviated. Without a doubt, « classical » neonatal screening programs are in the best interests of newborns. Indeed, those screening programs are recognized among the ten most important public health achievements. However, newborn screening programs raise ethical, legal and social challenges. For example, which criteria should govern whether or not to include a disease in the list of screened co [...]

by Robert F. Miller  , Laurence Huang  and Peter D. Walzer

Received: 14 September 2018;  Published: 25 October 2018;  doi: 10.21926/obm.genet.1804045

Background: Over the past decade, there has been rising interest in the interaction of Pneumocystis with the environment. This interest has arisen in part from the demonstration that environmental factors have important effects on the viability and transmission of microbes, including Pneumocystis. Environmental factors include climatological factors such as temperature, humidity, and precipitation, and air pollution factors including carbon monoxide, nitrogen dioxide, sulfur dioxide, and particulate matter. Methods [...]

by Marie Jardine  , Anna Miles  and Jacqui Allen

Received: 07 November 2020;  Published: 25 December 2020;  doi: 10.21926/obm.geriatr.2004146

Generalisations and misconceptions about ageing and swallowing can influence clinical opinion. Assumptions about swallowing function based on someone’s age risk overmedicalising or, conversely, undertreating older patients. Evidence suggests that increased prevalence of swallowing problems in older age is attributed to pathology known to affect swallowing function, or an unrelated serious illness and combination of health factors, and not ageing itself. This review highlights factors clinicians should consider when [...]

by Melissa Gaule  , Erin Allen  and Kathleen Benton

Received: 29 March 2020;  Published: 26 August 2020;  doi: 10.21926/obm.icm.2003037

by Jean-Lionel BAGOT

Received: 22 April 2022;  Published: 11 July 2022;  doi: 10.21926/obm.icm.2203026

The application of targeted therapies (TT) in oncology has prolonged survivals and even enabled complete remission of cancers previously considered incurable. With small therapeutic indices, the reduction in dosage or spacing out of the doses of TT due to side effects, represents a significant loss of treatment opportunity for the patients. In the absence of drug interaction and significant side effects, homeopathy used in supportive care improves the quality of life of patients, compliance with oncological treatme [...]

by Yash Aryan  and Anil Kumar Dikshit

Received: 26 July 2022;  Published: 09 November 2022;  doi: 10.21926/jept.2204035

Electric vehicles are becoming popular among consumers while BS-VI norms have been introduced and mandated for conventional vehicles in India. In the present study, the environmental impacts from the use phase of electric two-wheeler (EV) and gasoline two-wheeler (GV) have been evaluated and compared using the life cycle assessment (LCA) perspective. The functional unit adopted was 1000 km driven by one vehicle under Indian road and traffic conditions. CML 2001 and ReCiPe 2016 methods were used for the assessment u [...]

by Preeti Chhabra  and Kenneth L. Brayman

Received: 20 September 2020;  Published: 16 November 2020;  doi: 10.21926/obm.transplant.2004125

Clinical islet allotransplantation represents a minimally invasive, efficacious alternative to pancreas transplantation for restoring glycemic control and insulin independence in select patients with type 1 diabetes that is complicated by intractable impaired hypoglycemia awareness and/or severe hypoglycemic events refractory to stabilization by other means. Over the last decade, islet transplantation outcomes have steadily improved in part due to refinements in the selection of optimal donors, islet isolation tech [...]

by Lei Zhang  , Xian-Zhang Hu  , Xiaoxia Li  , Jacob Dohl  , Tianzheng Yu  and Robert J. Ursano

Received: 28 December 2018;  Published: 21 March 2019;  doi: 10.21926/obm.geriatr.1901041

Depression, PTSD, and hostility are common mental conditions that are associated with aging. A growing body of research has highlighted the possible effects of depression, PTSD, and hostility on aging and telomere length (TL), a cellular aging marker. Individuals who exhibit excessive responses to stressors show notable circulating inflammatory responses with high cortisol reactivity, which increases cell turnover and oxidative stress and may subsequently contribute to shortened TL. This review focuses on the most [...]

by Inês Lopes Cardoso

Received: 17 April 2018;  Published: 27 July 2018;  doi: 10.21926/obm.genet.1803025

Some repeats of three or more nucleotides in tandem, which are present in a gene or in its vicinity, tend to increase in number and for this reason are called dynamic mutations. These triplet repeats are unstable and can expand from one generation to the next. According to the expansion size, an unaffected individual can carry a pre-mutation that will expand through generations leading to the development of triplet repeat expansion diseases. The increase in the number of repeats over time leads to earlier developme [...]

by Michael Frass  and Katharina Gaertner

Received: 16 January 2019;  Published: 16 April 2019;  doi: 10.21926/obm.icm.1902023

This case reports of a 71-year-old patient with polycythemia vera (PCV). Homeopathic treatment began 15 years after his diagnosis at the age of 51. The frequency of phlebotomies was lowered significantly after the start of the homeopathic treatment; the patient survived another 16 years without chemotherapy, which he had rejected despite appropriate education. For someone with PCV who denied chemotherapy, this patient had a long survival time of more than 30 years, essentially enjoying good health and high quality [...]

by Riccardo Misto

Received: 19 November 2020;  Published: 24 May 2021;  doi: 10.21926/obm.icm.2102019

Using musical scales in a therapeutic key is one of the fundamental music therapy techniques of the Yoga of Sound (Nāda Yoga). The practice consists of singing particular sound formulas (scales), which are devised on a logical mathematical basis formed by specific musical intervals. These scales can bring to the surface, in a clear (objective), recognizable, and predictable way, psycho-emotional states and transform the blocked emotional energies. These blocked emotional energies are caused by repeated emotional st [...]

by Andrew C. Chien  , Eric Y. Lin  and Nicole J. Ye

Received: 26 April 2021;  Published: 11 June 2021;  doi: 10.21926/jept.2102024

The metallic copper, alkaline earth metal oxide, boron, and perovskite were incorporated on the surface of a Ni-cermet anode, and the performance of the modified Solid Oxide Fuel Cell (SOFC) anode was evaluated. The cell performance was analyzed by voltage-current characteristics (V-I curve) and H2-CH4 step reactions (P-t curve) in a potentiostatic mode. Besides, we also determined if a metallic phase or high electronic conductivity of the anode is important for a cell to perform well when H2 is used as a fuel, whe [...]

by BAGOT Jean-Lionel

Received: 31 May 2018;  Published: 15 September 2018;  doi: 10.21926/obm.icm.1803019

Background: After fatigue, pain is one of the major complaints from cancer patients. Regular use of Class 1 analgesics may cause side effects and is not always sufficient to relieve pain. Homeopathy is the complementary and integrative medicine most frequently used in France in supportive care in oncology (SCO). What is its place in the treatment of pain? Method: Extraction and analysis of results concerning pain from three surveys, two of which were carried out in France, on the main indications of homeopathy in S [...]

by Hanane Merhmi  , Maria Zerkaoui  , Abdelhafid Natiq  , Aziza Sbiti  , Thonas Liehr  and Abdelaziz Sefiani

Received: 25 July 2018;  Published: 22 July 2019;  doi: 10.21926/obm.genet.1903085

Background: A report of two new Moroccan cases with polymalformative syndrome, in which we identified similar but not identical sSMCs derived from chromosome 14. Methods: Conventional karyotype and MULTI-FISH. Results: +del(14)(q21.1) in the first case and +del(14)(q21.2) in the second. Conclusions: Constitutional partial trisomy 14 has an expanded clinical spectrum as one case from the literature was associated with gonadal tumor development. Similar cases, including the ones reported here, need to be carefully fo [...]

by Lucia D. Willems  , Stefania V. Vacaru  , Hannelies Hokke  and Paula S. Sterkenburg

Received: 30 May 2022;  Published: 24 August 2022;  doi: 10.21926/obm.icm.2203037

Individuals with intellectual disabilities (ID) are at a higher risk of shame and self-criticism and tend to make downward social comparisons. Compassion-focused therapy (CFT) is commonly used to address these issues in the general population, however, information on the adaptability and effectiveness of CFT for individuals with ID is limited. Thus, we conducted a scoping review of studies on CFT for individuals with ID, to accumulate and consolidate the information and provide a basis for future studies to further [...]

by Ryan A. Williams  , Lorna Hatch  and Simon B. Cooper

Received: 29 April 2019;  Published: 02 August 2019;  doi: 10.21926/obm.icm.1903049

It is well documented that an acute bout of exercise has a positive effect on subsequent cognitive function in children and adolescents. However, the effect of: the exercise characteristics (i.e. intensity, duration and modality), the cognitive domain assessed, and moderating variables (such as the participant’s age, physical fitness and baseline cognitive abilities); all of which affect this relationship are poorly understood. Therefore, the purpose of this review is to examine the impact of these variables on the [...]

by Mojtaba Ehsanifar  and Alireza Esmaeili

Received: 14 January 2025;  Published: 15 April 2025;  doi: 10.21926/obm.neurobiol.2502284

Neurotoxicity occurs when exposure to a biological, chemical, or physical agent, especially a neurotoxin, alters the normal activity of the nervous system in a way that results in permanent or reversible damage to neurons and nerve tissue and disrupts the functioning of the brain and nervous system. Chlorpyrifos is a broad-spectrum organophosphorus insecticide that has been used worldwide for more than 50 years and can damage the nervous system of insects by creating neurotoxicity. Epidemiological studies show that [...]

by Lucy Watts  , Joanna Smith  , Wilfred McSherry  , Michael Tatterton  and Alison Rodriguez

Received: 04 November 2019;  Published: 03 March 2020;  doi: 10.21926/obm.icm.2001012

In palliative and end of life care settings supporting people to make sense of their lives is as important as managing disease symptoms. Dignity Therapy is a validated psychotherapeutic intervention designed to bring about a sense of meaning and purpose for individuals at the end of life. Dignity Therapy has primarily been implemented and evaluated in adult palliative care settings. Prior to designing studies that evaluate Dignity Therapy for children and young people with life-limiting and life-threatening conditi [...]

by Deewakar Poudel  , Benjamin Belfore  , Shankar Karki  , Grace Rajan  , Sina Soltanmohammad  , Angus Rockett  and Sylvain Marsillac

Received: 28 October 2020;  Published: 06 January 2021;  doi: 10.21926/jept.2101001

The effect of water ingress on the surface of the buffer layer of a Cu(In, Ga)Se2 (CIGS) solar cell was studied. Such degradation can occur either during the fabrication process, if it involves a chemical bath as is often the case for CdS, or while the modules are in the field and encapsulants degrade. To simulate the impact of this moisture ingress, devices with a structure sodalime glass/Mo/CIGS/CdS were immersed in deionized water. The thin films were then analyzed both pre and post water soaking. Dynamic second [...]

by Jaspreet Kaur  , Khushveer Kaur  , Khushwinder Kaur  , Avtar S. Matharu  and Surinder K. Mehta

Received: 14 December 2022;  Published: 14 April 2023;  doi: 10.21926/aeer.2302027

Continued industrialization, urbanization and ecological destruction have caused significant environmental problems, particularly increased water pollution. Introducing harmful organic and inorganic effluents into watercourses has limited the supply and accessibility of safe and affordable drinking water. There is an urgent need to find green and sustainable abatement solutions for water remediation, many based on nanoparticles. The primary objective of this review is to explore and have a comprehensive discussion [...]

by Tiffany Field

Received: 28 April 2018;  Published: 25 September 2018;  doi: 10.21926/obm.geriatr.1803012

This narrative review is based on literature searches of PubMed and PsycINFO using the terms online dating in older adults. The papers that met inclusion criteria include content analyses of online dating profiles and interviews with online dating individuals. The issues that emerged from this literature included online versus off-line advantages and disadvantages, online profile characteristics that differ by age and gender and online use problems. Online versus off-line dating older adults have reputedly experien [...]

by Sergey B. Yurchenko

Received: 25 May 2021;  Published: 14 July 2021;  doi: 10.21926/obm.neurobiol.2103103

This article reviews the modern approaches to the quantum brain hypothesis. The aim is to consider the hypothesis and its classical brain-machine alternative from a broad perspective, including physics, biology, computer science, cosmology, and metaphysics. My starting point is that asking whether consciousness can or cannot have free will is fundamentally incorrect. This aspect is challenged by both physics and neuroscience. The paper argues that the search for conscious free will, as it is typically tested in Lib [...]

by A. Guillermo Bracamonte

Received: 24 November 2024;  Published: 18 February 2025;  doi: 10.21926/rpm.2501007

The generation of non-classical light with improved performances within tiny sizes, intervals of lengths, and diameters is still a challenge. The generation of variable wavelengths associated with different frequencies of energy modes produced from new sources of emitters within confined scales from the Quantum to Nano-and Micro-scales are of high impact. It is noted here that the concept of the generation of non-classical light related to electronics and photonics interactions with different topological matter con [...]

by Shruthi Kodad  , Waleed Sabry  , Assem Elsayed  , Hadi Goubran  and Mohamed Elemary

Received: 25 June 2019;  Published: 26 August 2019;  doi: 10.21926/obm.transplant.1903081

Hematopoietic stem cell transplant (HSCT) recipients are at an increased risk of bacterial, viral, fungal and parasitic infections. Past exposures to infections, the degree of immunosuppression, prolonged neutropenia and presence of graft versus host disease (GVHD) are some of the factors which make HSCT recipients more susceptible to infections. Viral infections have emerged as a major challenge causing high morbidity and mortality in stem cell transplant recipients. Myeloablative conditioning regimens and GVHD pr [...]

by Hideya Mizuno  , Ayako Taketomi  and Toshikatsu Nakabayashi

Received: 27 June 2018;  Published: 27 September 2018;  doi: 10.21926/obm.icm.1803021

St. John’s wort (SJW), or Hypericum perforatum, is a perennial herb that is used to treat depression in several countries. Based on the available evidence, it can be hypothesized that SJW would also have beneficial prophylactic and therapeutic effects in patients with metabolic syndrome. In this review, we summarize and discuss the best designed studies that have investigated the effects of SJW extract on adipocyte differentiation, the inflammatory process, and glucose metabolism, all of which are relevant to [...]

by Alexandra Koulouris  , Kathleen Dorado  , Christina McDonnell  , Robert R. Edwards  and Asimina Lazaridou

Received: 27 June 2018;  Published: 05 September 2018;  doi: 10.21926/obm.icm.1803018

Background: This paper presents a review of the evidence regarding the efficacy and impact of Yoga and mindfulness with meditation among patients with rheumatoid arthritis (RA). Patients who suffer from RA express a variety of symptoms that negatively impact their physical functioning and performance in social roles. Yoga and meditation-based therapies have been previously used to manage chronic pain conditions and other persisting disorders in affected populations. The suitability and effectiveness of these practi [...]

by Sue Anne Fuller  and Peta Stapleton

Received: 17 June 2021;  Published: 26 October 2021;  doi: 10.21926/obm.icm.2104038

A 37-year-old female with a history of complex trauma, anxiety and depression was treated with Emotional Freedom Techniques (EFT) supplemented with guided imagery within the first 24 hours of having a stroke that affected the right side. CT scans indicated a haemorrhage and brain clot. Surgery was delayed as another seizure was expected. Interventions occurred during COVID-19 restrictions. The patient then engaged in 90 minutes of EFT every day over the course of a week while in hospital. After seven days she was d [...]

by Ilir Deva  and Renata van der Weijden

Received: 15 October 2021;  Published: 23 December 2021;  doi: 10.21926/aeer.2104037

Due to climate change, flood-related disasters are expected to increase. Floods generate enormous amounts of waste, including electronic waste (e-waste). E-waste should be recovered not only because it can have detrimental effects on human health and the environment but also because of the valuable metals contained in it. In this study, a system dynamics model based on current practices and waste management was established using Vensim to determine the revenue that can be generated by e-waste recycling after floods [...]

by Karolina Bryl  and Jacelyn Biondo

Received: 25 August 2021;  Published: 26 November 2021;  doi: 10.21926/obm.icm.2104052

Dance/movement therapy (DMT) is a strengths-based approach to psychotherapy that uses dance and movement as the primary form of communication, while emphasizing the movement relationship in addition to verbal dialogue. Positive and negative symptomatology of a diagnosis on the schizophrenia spectrum often disrupt organized thinking, orientation to reality, overall functioning, communication, and healthy relationships. Therefore, a body-based psychotherapeutic approach can be a pragmatic way to support, join, and pr [...]

by James S. Powers  , Michelle Moseley  , Lovely Abraham  , Jennifer Buckner  , Nkechi Azubike  and Catherine Xie

Received: 21 May 2018;  Published: 13 August 2018;  doi: 10.21926/obm.geriatr.1803008

Background: A Veterans Health Administration (VHA) patient centered medical home, the Geriatric Patient- Aligned Care Team (GeriPACT). Methods: Plan-Do-Study-Act (PDSA) cycles regarding strategy, resource development, patient and caregiver experience of care, and clinical care process improvement. Stakeholder engagement for half-time operation with initial grant support for personnel who also had collateral duties. Tracking of operations data. Results: The clinic population grew from 200 to 627 over a 7-year period [...]

by Samskruthi Menashi  , Lawrence B Cohen  and Manuela G. Neuman

Received: 10 February 2018;  Published: 28 March 2018;  doi: 10.21926/obm.icm.1801002

Ayurveda is an ancient Indian medicinal practice. The present review includes translational research characterizing obesity, non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH). We reviewed published research on improving function through Ayurvedic medicine by searching electronic databases (Medline, Embase) using terms such as: Ayurveda, obesity, NAFLD, NASH, the effect of exercise interventions in obesity, change in body composition. We aim to (1) determine the immuno-pathology of [...]

by Angela Q Maldonado  , Kristoffer Sjöholm,  , Joshua Lee  , Håkan Olsson  , Christian Kjellman  and Darren E Stewart

Received: 01 April 2021;  Published: 03 June 2021;  doi: 10.21926/obm.transplant.2102143

Prioritization in the US Kidney Allocation System (KAS) has led to an improvement in the rates of transplantation in highly sensitized (HS) patients. However, there is a subset of HS patients who are at a disadvantage, despite prioritization under KAS. The purpose of this study was to describe the transplant rate (TR) by calculated panel reactive antibody (CPRA) of HS candidates before and five years post-KAS to characterize their access to deceased donor transplants and quantify the number of HS candidates who are [...]

by Martine S. Bosma  , Monique A.A. Caljouw  , Jacqueline K. Benfield  , Laura Edwards  , Tanja C.W. Nijboer  and Wilco P. Achterberg

Received: 07 December 2020;  Published: 19 March 2021;  doi: 10.21926/obm.geriatr.2101163

Visuospatial neglect (VSN) adversely impacts both the length of rehabilitation and activities of daily living (ADL) of patients after stroke and can reduce their participation in community activities. Therefore, it is important to assess VSN after stroke in neurorehabilitation facilities. The process of assessing VSN comprehensively in current geriatric rehabilitation remains unclear. This study examined the process of VSN in post-stroke assessment emphasizing the details of the (systematic) routines and structure [...]

by Mario F. Tecce  , Walter Milano  and Anna Capasso

Received: 26 June 2020;  Published: 31 August 2020;  doi: 10.21926/obm.icm.2003038

Adipocytes play a central role in maintaining lipid homeostasis and energy balance by storing triacylglycerols (TAGs) or releasing free fatty acids in response to changes in energy requirements. Obesity is a major risk factor for many diseases, including diabetes, hypertension, and cardiovascular disease. Besides, morbidity and mortality associated with being overweight and obese are on the rise. The development of obesity is characterized by an increase in lipid cells due to mitogenesis and differentiation, which [...]

by Caymen M. Novak  , Eric N. Horst  , Shreya Raghavan  and Geeta Mehta

Received: 17 June 2019;  Published: 06 September 2019;  doi: 10.21926/obm.genet.1903092

Background: Invasive breast cancer affects 1 in 8 women in the United States and causes one of the highest cancer mortality rates for women. Cyclooxygenase-2 (COX-2), a central enzyme in prostaglandin biosynthesis, is implicated in breast cancer initiation, progression, invasion, and metastasis, and has been linked to the mechanotransduction of breast cancers. However, it is not currently known if shear stress mediated mechanotransduction is affected by COX-2. Therefore, in this report, we hypothesized that COX-2 m [...]

by Peta Stapleton  and Hannah Chatwin

Received: 17 May 2018;  Published: 02 July 2018;  doi: 10.21926/obm.icm.1803014

(1) Background: Because patients vary in their response to treatment, including adherence, the effect of treatment length in the use of EFT on food cravings was examined by comparing two studies in order to ascertain if shorter programs are as effective. This may then impact treatment adherence and completion. (2) Methods: In study one, 96 overweight and obese adults were randomly allocated to a 4-week treatment for their food craving or waitlist condition. In study two, an 8-week EFT program for 47 adults, the sam [...]

by David W. Scharp  , Jayagowri Arulmoli  , Kelly Morgan  , Hannah Sunshine  and Ergeng Hao

Received: 15 October 2018;  Published: 26 February 2019;  doi: 10.21926/obm.transplant.1901052

Background: This presentation of a six-year study processing human islets for research and transplantation includes a review of multi-center transplant studies identifying key variables critical for successful islet processing and defines standardized processing procedures required to provide highly purified, functional Human Islets. Methods: Human islet processing methods are defined in detail with pancreas retrieval, shipping, trimming for processing, collagenase distension, controlled digestion by digestion/filt [...]

by Arianna Massaro  , Ana B. Muñoz-García  , Mariarosaria Tuccillo  , Michele Pavone  and Pier Paolo Prosini

Received: 02 November 2020;  Published: 10 June 2021;  doi: 10.21926/jept.2102022

The current state-of-the-art quantum mechanics methodologies were applied to derive information on the bulk and surface properties of the P2-type layered oxide Na0.85Li0.17Ni0.21Mn0.64O2 (NLNMO), a cathode material. The special quasi-random structure (SQS) approach was employed to identify the arrangement of Li, Ni, and Mn ions in a supercell containing 115 atoms. Both the cell parameters and atomic positions were determined from DFT-PBE+U calculations to highlight specific distortions induced by the dopants (Ni an [...]

by Ana Luísa Tomás  and Olga Matos

Received: 21 August 2018;  Published: 13 November 2018;  doi: 10.21926/obm.genet.1804049

Pneumocystis jirovecii pneumonia (PcP) remains a major cause of respiratory illness among immunocompromised patients. PcP is difficult to diagnose, in particular in non-HIV-infected patients, due to the lack of associated specific clinical data. Since P. jirovecii could not be cultivated for many years, microscopic visualization of cystic or trophic forms in respiratory specimens based on cytochemical or immunofluorescence staining are the standard procedure to identify this fungus. Polymerase chain reaction (PCR)- [...]

by Kelly Armstrong  , Raman Gokal  and Todd Todorsky

Received: 25 March 2019;  Published: 25 September 2019;  doi: 10.21926/obm.icm.1903056

Background: Direct Current (DC) micro-current point stimulation (MPS) is increasingly recognized as a therapy for chronic pain and stress management. However, there remains limited evidence as to the therapeutic value of MPS in chronic post surgical pain (CPSP) management related to C-Section scars. Objectives: We aimed to determine the effect and magnitude that MPS has when applied to C-section scars and its effects on a wide variety of non-specific chronic post surgical pain syndromes. Study Design: This was a co [...]

by Junmo Moon  , Satita Thiangtham  , Ruijie Zheng  , Sicheng Liu  , Chayanaphat Chokradjaroen  , Yasuyuki Sawada  and Nagahiro Saito

Received: 04 December 2022;  Published: 20 February 2023;  doi: 10.21926/jept.2301010

Crystalline lithium fluoride (LiF) has been intensively pursued as potential alternative solid electrolytes (SEs) owing to its excellent chemical and electrochemical oxidation stability, and good deformability. However, due to its low ion conductivity, LiF is still challenging for practical SE applications. Herein, Li-Zr-F composite-based SE by liquid-mediated synthesis is proposed to be studied. methanol (CH3OH) was mainly evaluated as a liquid-mediated precursor for synthesizing Li-Zr-F composites under the stoic [...]

by Kevin T Ong

Received: 15 May 2018;  Published: 03 September 2018;  doi: 10.21926/obm.geriatr.1803011

Amyloid positron emission tomography (PET), fluorodeoxyglucose (FDG) PET, and magnetic resonance imaging (MRI) are three modalities in the imaging of Alzheimer’s disease (AD). This article reviews the experience and data obtained from AD research using these techniques to understand the natural history of AD and to enhance therapeutic trials. It is now realised that their use can improve early detection of AD, and has opened a new corridor which may lead toward successful treatment.

by Georgia Kakourou  , Thalia Mamas  , Christina Vrettou  and Jan Traeger-Synodinos

Received: 03 June 2019;  Published: 22 July 2019;  doi: 10.21926/obm.genet.1903084

Preimplantation Genetic Testing for HLA-matching (PGT-HLA) has been one of the most controversial PGT applications, first reported in 2001. The procedure aims to identify an embryo that is not only healthy but also HLA-matched with a sibling in the family in need of haematopoietic stem cell transplantation (HSCT), considering that sibling HSCT stands the highest chance of success in comparison to alternative approaches. HLA-typing can be performed with or without PGT-M for the exclusion of a single-gene disorder. T [...]