1. Neuroscience Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran
2. University of Greenwich, and Consultant Physician, Queen Elizabeth Hospital, Woolwich, London, UK
3. Shiraz Geriatric Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
4. Physical Medicine and Rehabilitation, Bone and Joint Diseases Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
Academic Editor: Donatella R. Petretto
Special Issue: Dysphagia in the Elderly
Received: November 14, 2019 | Accepted: February 12, 2020 | Published: February 20, 2020
OBM Geriatrics 2020, Volume 4, Issue 1, doi:10.21926/obm.geriatr.2001109
Recommended citation: Farpour S, Smithard D, Farpour HR. Dysphagia and Oral Health in Older People. OBM Geriatrics 2020;4(1):10; doi:10.21926/obm.geriatr.2001109.
© 2020 by the authors. This is an open access article distributed under the conditions of the Creative Commons by Attribution License, which permits unrestricted use, distribution, and reproduction in any medium or format, provided the original work is correctly cited.
Swallowing is a well-coordinated and complicated process that consists of four phases, the primary purpose of which is the transfer of food from the mouth to the pharynx. In the oral preparatory phase, a voluntary step, food or liquids are placed in the mouth, and a bolus is formed and held between the tongue and the palate before being transferred to the pharynx. There are some differences between liquids and solids in this phase. Solid foods should be chewed while liquids do not need chewing. The Glossopalatal Junction (GPJ) plays an important role by preventing the bolus from falling into the pharynx before the oropharyngeal swallowing reflex (OSR) is triggered. In the oral propulsive phase, the bolus is transferred through the mouth to the pharynx by tongue. The bolus is transferred through the pharynx by the propulsive forces of the tongue. Further, the bolus enters the pharynx (3rd phase) and is pushed by the pharyngeal stripping wave. In this phase, the pharyngeal contraction facilitates pharyngeal clearance. This phase is an automatic, involuntary phase that begins with the crosses of the bolus through the pillars of fauces by propulsive tongue trust. The configuration of oral cavity and pharynx which is defined as opening and closing events in Glossopalatal junction, velopharyngeal junction, laryngeal vestibule, and upper esophageal sphincter is essential for the safety of swallowing as these events arranged the oropharyngeal structure from a respiratory to a digestive pathway. After passing through the upper esophageal sphincter, the passage to the stomach continues via the esophagus (4th phase) by peristalsis .
Dysphagia is a term for swallowing disorders and defined as difficulty in moving the food (liquids or solids) from the mouth to the stomach . Dysphagia has many complications including death [1,2,3,4]. Older people and in particular, very old, frail people are most at risk of dysphagia [1,3,4]. Studies reported 13% of the population with 65 or more years of age, 47% of frail elders who are hospitalized for acute illnesses, and 40–60% of elders from nursing homes had dysphagia. The prevalence increases if the old age co-morbid with neurological or neurodegenerative disorders such as Parkinson's disease (60%), Alzheimer's (80%), or stroke (30–78%). Dysphagia has many life-threatening complications such as malnutrition, dehydration, increased length of hospitalization, increased risk of mental health disorders such as anxiety and decreased quality of life (1). In view of the high prevalence of dysphagia in this population, its multiple etiology, associated co-morbidities and complications resulting in functional decline and a poor prognosis, dysphagia is considered to be a geriatric syndrome [4,5,6]. The management of dysphagia requires a multidisciplinary approach for diagnosis and management . The constituent members of the multidisciplinary team often vary between the health team, within and between countries and regional areas . For example, in some health care systems, dentists or dental hygienists are not routinely employed in the acute or rehabilitation setting to assist in the diagnosis and management of dysphagia .
Therefore, this article aims to highlight the relationship between dysphagia and some prevalent oral problems in frail older people and the roles a dentist or a dental hygienist can play in this domain to improve their care delivery to prevent malnutrition and pneumonia.
2. Dry Mouth and Dysphagia
Dry mouth is a prevalent oral symptom. The two dry mouth problems should be differentiated from each other: xerostomia, which is defined as a subjective feeling of dry mouth, and hypo-salivation, an objective finding, which is a decrease in salivary production. These two problems are associated with each other. However, they may be present separately in a patient. For example, xerostomia may be present in a patient with a normal saliva flow rate .
Saliva is a key factor in protecting oral tissues, moisturizing the mucosa, remineralizing the tooth surface, bolus formation and retaining removable prosthesis [7,8,9,10]. With age, saliva production decreases, but not to a rate that will cause difficulty in swallowing unless a disease process or medication intervenes. Lack of saliva, without appropriate mouth care, will result in tooth loss and difficulty in the retention of the dental prosthesis. Reduction in teeth and ill-fitting dental prosthesis makes chewing inefficient and is followed by inadequate bolus formation [8,11].
Studies showed that xerostomia has the potential to increase the risk of dysphagia by changing taste, mastication of food, and bolus formation. Also, hyposalivation increases the risk for several oral diseases such as dental caries, candidiasis, bad breath, burning/sore mouth, taste disturbances, difficulties in chewing and swallowing .
Many older people have multiple long term conditions, which will result in significant polypharmacy. These medications with a significant anticholinergic effect (Tricyclic antidepressants, opiates) may induce xerostomia and hyposalivation, therefore increasing susceptibility to oral health issues, mainly dysphagia .
3. Tooth Loss and Dysphagia
Tooth loss has many etiological factors, including dental caries , periodontal diseases and gingivitis , and trauma. Dysphagia has the potential to increase the risk of dental caries in the patients compared to the healthy population due to increase contact time between sugars and teeth when dysphagia is present . Additionally, periodontal disease and gingivitis are more prevalent in patients with dysphagia .
If the number of teeth is below a critical number, chewing becomes less efficient, and the bolus is less well formed. This may result in an early or fragmented presentation of the bolus to the pharynx leading to an unsafe swallow [8,15]. Also, tooth loss and the presence of dentures will influence occlusal force and lead to a decrease in the eating of hard/firm fruit and vegetables . Therefore, tooth loss and mastication insufficiencies cause limitations in diet and food choices and thus indirectly increase the risk of mortality .
Although studies support that dentures can reduce the complications of tooth loss [18,19], it also promotes some problems such as the high risk of candida, denture stomatitis [20,21] and pneumonia [22,23], especially if the dental plates are not kept clean, which should be considered.
4. Dental Caries and Dysphagia
The relationship between dysphagia and dental caries is complex. Dental caries and tooth decay are the most prevalent chronic diseases in frail older people [24,25]. Dental caries is a multifactorial disease, affecting both the crown (coronal caries) and root (root caries). Caries is the result of the interaction of acid-producing bacteria and fermentable carbohydrate with the teeth, especially if the saliva flow is low .
5. Periodontal Diseases and Dysphagia
Periodontal disease is a disorder of periodontium, a tissue that surrounds and supports teeth and its mildest form is gingivitis. Bacterial biofilm (dental plaque), which accumulates on teeth, can cause gingivitis. Gingivitis does not affect the surrounding tissues; however, as the disease progresses, periodontitis will appear that can cause loss of connective tissue and bone support . Severe periodontitis can also cause tooth loss, occasional pain and masticatory problems .
6. Dysphagia, Poor Oral Health, Malnutrition, and Aspiration Pneumonia
Poor oral health, dysphagia, and malnutrition are related to each other and each has the potential to be a cause and the result of each other [3,13]. These three factors are also critical risk factors for aspiration pneumonia .
The relationship between the oral microbiome and the lungs is considered to be the same, with microorganisms moving from the mouth to the lungs and then being removed by mucus and the mucociliary waves. Ordinarily, this does not lead to any problem. However, in the presence of significant morbidity (frailty, cancer, diabetes, stroke), immunity is suppressed and a chronic inflammatory state persists. This then increases the likelihood of pneumonia, often termed as “aspiration pneumonia.” The literature suggests that the most prevalent organisms are Streptococci, Haemophilus species and Chlamydia species [28,29]. These gram-negative species colonize different parts of the oral cavity such as gingiva (especially in periodontitis), teeth (dental plaque and cavitated lesions), oral mucosal surfaces, saliva, denture surfaces and tongue (especially the dorsum of the tongue) [28,30,31,32]. They can be released from different surfaces of the oral cavity into salivary secretions and thus, aspirating these gram-negative species with saliva and or food into the lower respiratory tract will increase the risk of pneumonia [30,31].
Aspiration may be seen following video-fluoroscopy or fiberoptic endoscopic evaluation of swallowing (FEES), but not all people aspirating develop pneumonia [4,33,34]. The diagnosis of aspiration pneumonia is often misdiagnosed with community-acquired pneumonia.
Swallowing problems, as well as poor oral hygiene, may lead to respiratory infections such as aspiration pneumonia by aspirating gram-negative living microorganisms in the oral cavity . Therefore, improving oral care is essential to reduce the risk of pneumonia .
According to the above information, dysphagia and dental problems can both result in a vicious cycle and should be considered in a multidisciplinary dysphagia team.
7. Roles of Dentists, Dental Hygienists and Dental Nurses in Dysphagia Multidisciplinary Teams
Given the relationship between dysphagia and oral health (Table 1), it is believed that dentists, dental hygienists, and dental nurses play an essential role in dysphagia diagnosis and management. They work together as a team, while dentists are responsible for dental treatments, dental hygienists provide oral care and play an important role in long term management of dental care at home . In this view, some diagnostic tools are made for dental professionals to facilitate the identification of dysphagia. One of these tools is the Dentist Swallowing Assessment Test (Den SAT). Den SAT is a simplified accurate assessment tool used by dentists to identify elders with dysphagia. Therefore, dentists are key members in identifying signs and symptoms of deglutition problems and referring patients to speech therapists or swallowing therapist for further assessment and treatment .
8. Oral Hygiene
Along with the early diagnosis, appropriate interventions should be considered in a multidisciplinary manner. Minimal Massive Intervention (MMI) is a cost-effective, evidence-based program which is based on three interventional domains: 1- compensatory interventions such as fluid and food texture adaptation to improve the safety of swallowing; 2- nutritional supplementation to avoid malnutrition; 3- oral health to decrease the load of respiratory pathogens from oral cavity. Speech therapists, dietitians, dentists/dental nurses/dental hygienists as well as doctors, are the critical health providers in this kind of intervention .
Dysphagia is a geriatric syndrome and needs a multidisciplinary point of view for its diagnosis and management to reduce its health-threatening complications. Oral health is related to dysphagia and should be considered to reduce the risk of aspiration pneumonia. According to the importance of oral health in preventing complications of dysphagia, dental professionals such as dentists, dental nurses, and dental hygienists can play an important role in both, diagnosis and management.
Sima Farpour: Contributions to the design of the article. Analysis, interpretation of data for the article. Drafting the article. Final approval of the version to be published. Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
David Smithard: Contributions to the conception and design of the article. Interpretation of data for the article. Revising the article critically. Final approval of the version to be published. Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Hamid Reza Farpour: Contributions to the design of the article. Interpretation of data for the article. Revising the article. Final approval of the version to be published. Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
The authors have declared that no competing interests exist.
- Clavé P, Shaker R. Dysphagia: Current reality and scope of the problem. Nat Rev Gastroenterol Hepatol. 2015; 12: 259-270. [CrossRef]
- Farpour S, Farpour HR, Smithard D, Kardeh B, Ghazaei F, Zafarghasempour M. Dysphagia management in Iran: Knowledge, attitude and practice of healthcare providers. Dysphagia. 2019; 34: 105-111. [CrossRef]
- Farpour S, Farpour H, Zakeri M. Oropharyngeal dysphagia in elderly people. J Rehabil Sci Res. 2018; 5: 120-123.
- Farpour S, Farpour HR, Smithard DG. Oropharyngeal dysphagia and its related health problems in Iranian elderly people: A scope of work for the future. Eur J Integr Med. 2018; 21: 94-100. [CrossRef]
- Baijens LW, Clave P, Cras P, Ekberg O, Forster A, Kolb GF, et al. European Society for Swallowing Disorders–European Union Geriatric Medicine Society white paper: Oropharyngeal dysphagia as a geriatric syndrome. Clin Interv Aging. 2016; 11: 1403-1428. [CrossRef]
- Smithard D. Dysphagia: A geriatric giant. Med Clin Rev. 2016; 2: 1-7. [CrossRef]
- Barbe AG. Medication-induced xerostomia and hyposalivation in the elderly: Culprits, complications, and management. Drugs Aging. 2018; 35: 877-885. [CrossRef]
- Brochier CW, Hugo FN, Rech RS, Baumgarten A, Hilgert JB. Influence of dental factors on oropharyngeal dysphagia among recipients of long‐term care. Gerodontology. 2018; 35: 333-338. [CrossRef]
- McMillan R. Dry mouth—a review of this common oral problem. Dent Nurs. 2013; 9: 638-644. [CrossRef]
- Turner M, Jahangiri L, Ship JA. Hyposalivation, xerostomia and the complete denture: A systematic review. J Am Dent Assoc. 2008; 139: 146-150. [CrossRef]
- Donaldson M, Epstein J, Villines D. Managing the care of patients with Sjögren syndrome and dry mouth: Comorbidities, medication use and dental care considerations. J Am Dent Assoc. 2014; 145: 1240-1247. [CrossRef]
- Rihs LB, da Silva DD, de Sousa MLR. Dental caries in an elderly population in Brazil. J Appl Oral Sci. 2009; 17: 8-12. [CrossRef]
- Poisson P, Laffond T, Campos S, Dupuis V, Bourdel‐Marchasson I. Relationships between oral health, dysphagia and undernutrition in hospitalised elderly patients. Gerodontology. 2016; 33: 161-168. [CrossRef]
- Ortega O, Parra C, Zarcero S, Nart J, Sakwinska O, Clavé P. Oral health in older patients with oropharyngeal dysphagia. Age Ageing. 2014; 43: 132-137. [CrossRef]
- Furuta M, Takeuchi K, Adachi M, Kinoshita T, Eshima N, Akifusa S, et al. Tooth loss, swallowing dysfunction and mortality in Japanese older adults receiving home care services. Geriatr Gerontol Int. 2018; 18: 873-880. [CrossRef]
- Minakuchi S, Tsuga K, Ikebe K, Ueda T, Tamura F, Nagao K, et al. Oral hypofunction in the older population: Position paper of the Japanese Society of Gerodontology in 2016. Gerodontology. 2018; 35: 317-324. [CrossRef]
- Padilha DMP, Hilgert JB, Hugo FN, Bós ÂJG, Ferrucci L. Number of teeth and mortality risk in the Baltimore longitudinal study of aging. J Gerontol A Biol Sci Med Sci. 2008; 63: 739-744. [CrossRef]
- Wakabayashi H, Matsushima M, Ichikawa H, Murayama S, Yoshida S, Kaneko M, et al. Occlusal support, dysphagia, malnutrition, and activities of daily living in aged individuals needing long-term care: A path analysis. J Nutr Health Aging. 2018; 22: 53-58. [CrossRef]
- Takeuchi K, Izumi M, Furuta M, Takeshita T, Shibata Y, Kageyama S, et al. Denture wearing moderates the association between aspiration risk and incident pneumonia in older nursing home residents: A prospective cohort study. Int J Environ Res Public Health. 2019; 16: 554. [CrossRef]
- Compagnoni MA, Souza R, Marra J, Pero AC, Barbosa DdB. Relationship between Candida and nocturnal denture wear: Quantitative study. J Oral Rehabil. 2007; 34: 600-605. [CrossRef]
- Baran I, Nalçacı R. Self-reported denture hygiene habits and oral tissue conditions of complete denture wearers. Arch Gerontol Geriatr. 2009; 49: 237-241. [CrossRef]
- Iinuma T, Arai Y, Abe Y, Takayama M, Fukumoto M, Fukui Y, et al. Denture wearing during sleep doubles the risk of pneumonia in the very elderly. J Dent Res. 2015; 94: 28S-36S. [CrossRef]
- O'Donnell LE, Smith K, Williams C, Nile CJ, Lappin DF, Bradshaw D, et al. Dentures are a reservoir for respiratory pathogens. J Prosthodont. 2016; 25: 99-104. [CrossRef]
- Preza D, Olsen I, Aas JA, Willumsen T, Grinde B, Paster BJ. Bacterial profiles of root caries in elderly patients. J Clin Microbiol. 2008; 46: 2015-2021. [CrossRef]
- Selwitz RH, Ismail AI, Pitts NB. Dental caries. Lancet. 2007; 369: 51-59. [CrossRef]
- Pihlstrom BL, Michalowicz BS, Johnson NW. Periodontal diseases. Lancet. 2005; 366: 1809-1820. [CrossRef]
- Martín A, Ortega O, Roca M, Arús M, Civit PC. Effect of a minimal-massive intervention in hospitalized older patients with oropharyngeal dysphagia: A proof of concept study. J Nutr Health Aging. 2018; 22: 739-747. [CrossRef]
- Mandell LA, Niederman MS. Aspiration pneumonia. N Engl J Med. 2019; 380: 651-663. [CrossRef]
- Ebihara S, Sekiya H, Miyagi M, Ebihara T, Okazaki T. Dysphagia, dystussia, and aspiration pneumonia in elderly people. J Thorac Dis. 2016; 8: 632-639. [CrossRef]
- Terpenning MS, Taylor GW, Lopatin DE, Kerr CK, Dominguez BL, Loesche WJ. Aspiration pneumonia: Dental and oral risk factors in an older veteran population. J Am Geriatr Soc. 2001; 49: 557-563. [CrossRef]
- Sumi Y, Miura H, Nagaya M, Michiwaki Y, Uematsu H. Colonisation on the tongue surface by respiratory pathogens in residents of a nursing home–a pilot study. Gerodontology. 2006; 23: 55-59. [CrossRef]
- Zuanazzi D, Souto R, Mattos MBA, Zuanazzi MR, Tura BR, Sansone C, et al. Prevalence of potential bacterial respiratory pathogens in the oral cavity of hospitalised individuals. Arch Oral Biol. 2010; 55: 21-28. [CrossRef]
- Fernández OO, Clavé P. Oral hygiene, aspiration, and aspiration pneumonia: From pathophysiology to therapeutic strategies. Curr Phys Med Rehabil Rep. 2013; 1: 292-295. [CrossRef]
- Morris J, Hollwey F, Hansjee D, Power R, Griffith R, Longmore T, et al. Pilot of a charter to improve management of medicines and oral care for residents with dysphagia in care homes. Geriatrics. 2018; 3: 78. [CrossRef]
- Kamijo S, Sugimoto K, Oki M, Tsuchida Y, Suzuki T. Trends in domiciliary dental care including the need for oral appliances and dental technicians in Japan. J Oral Sci. 2018; 60: 626-633. [CrossRef]
- Rech RS, Hugo FN, Baumgarten A, dos Santos KW, de Goulart BNG, Hilgert JB. Development of a simplified dysphagia assessment by dentists in older persons. Community Dent Oral Epidemiol. 2018; 46: 218-224. [CrossRef]