by Carmelo Guido  , Valentina Selmi  , Cosimo Chelazzi  , Giulia Borsotti  , Rita Giachetti  , Vittorio Limatola  , Martina Sicurani  and Angelo Raffaele De Gaudio

Received: 29 September 2018;  Published: 28 March 2019;  doi: 10.21926/obm.icm.1901020

Background: In recent years, complementary and alternative medicine (CAM) techniques have become very widespread; among these, acupuncture can play an important role in the treatment of adverse effects related to chemotherapy. This role has been recognized by the National Institutes of Health after many clinical studies, thus allowing the official introduction of acupuncture in supportive therapy for oncological diseases, particularly to prevent nausea and vomiting. The aim of this paper is to describe the activity [...]

by Aditi Gupta  , Bor-Jang Hwang  , Daniel Benyamien-Roufaeil  , Sara Jain  , Sophie Liu  , Rex Gonzales  , Robert A. Brown  , Michal Zalzman  and A-Lien Lu

Received: 22 July 2021;  Published: 02 April 2022;  doi: 10.21926/obm.geriatr.2202196

Telomeres consist of special features and proteins to protect the ends of each chromosome from deterioration and fusion. The telomeric DNA repeats are highly susceptible to oxidative damage that can accelerate telomere shortening and affect telomere integrity. Several DNA repair factors including MYH/MUTYH DNA glycosylase, its interacting partners Rad9/Rad1/Hus1 checkpoint clamp, and SIRT6 aging regulator, are associated with the telomeres. MYH prevents C:G to A:T mutation by removing adenine mispaired with a frequ [...]

by Collin J. Anderson  , Amanda C. Guidon  , Farrah B. Khan  , Alissa A. Thomas  , Carolyne Riehle  , Michael K. Hehir  and Noah A. Kolb

Received: 28 October 2020;  Published: 31 January 2021;  doi: 10.21926/obm.neurobiol.2101086

Lambert Eaton myasthenic syndrome (LEMS) is a rare autoimmune neuromuscular junction disorder involving loss of functional pre-synaptic P/Q-type voltage-gated calcium channels. Many cases occur as a paraneoplastic disorder, often in small cell lung cancer (SCLC). Recently, immune checkpoint inhibitors (ICI) have emerged as treatment of choice for various malignancies. While generally well tolerated, certain ICI-treated patients experience neurologic immune-related adverse events (irAEs). Here, we explore therapeuti [...]

by Yenlajai JaneFrances Banseka  and Suiven John Paul Tume

Received: 03 March 2024;  Published: 19 April 2024;  doi: 10.21926/aeer.2402010

Bacteriological contamination of water sources, often due to improper handling of human waste, poses significant public health risks. This study investigates coliform bacteria contamination in water sources across the Fako Division of Cameroon. Twenty water samples were collected from various sources, including streams, community water, springs, boreholes, and wells, and analyzed for total coliforms using Violet-Red-Bile-Lactose (VRBL) Agar. Additionally, 352 household questionnaires were administered in four towns [...]

by Joep P.M. Geraedts

Received: 15 December 2020;  Published: 28 January 2021;  doi: 10.21926/obm.neurobiol.2101085

Huntington’s disease (HD) is an autosomal dominant disease that immensely impacts the affected families. However, the transmission of the disease from carriers to their offspring could be prevented. Prenatal diagnosis (PND) and preimplantation genetic diagnosis (PGD) are the only two available reproductive options for the carriers at risk to have disease-free children. PND for HD could be done through two kinds of genetic testing: direct and indirect. The same approaches are available for preimplantation genetic te [...]

by Phil Ayers  , Megan Harlow  and LeAnn Scott

Received: 30 December 2021;  Published: 15 February 2022;  doi: 10.21926/rpn.2201002

Parenteral nutrition (PN) is a complex medication administered to adult, pediatric, and neonatal patients. PN is recognized as a high-alert medication by the Institute for Safe Medication Practices (ISMP). The American Society for Parenteral and Enteral Nutrition (ASPEN) has published several key recommendations regarding safe use of PN. This manuscript will review several of the important PN papers published in 2020-2021 by ASPEN.

by Mohamed Abutineh  , Nicholas Pizzo  , Nicholas Nifakos  , Xiao-Lu Jin  , John M Harlin  and Xing-Hai Zhang

Received: 26 October 2020;  Published: 18 February 2021;  doi: 10.21926/obm.genet.2101124

Citrus is an important group of globally produced fruit crops, holding great economic, cultural, and health value. Belonging to the Rutacaeae family, the genus Citrus includes some of the most iconic and widely appreciated variants of fruits such as the orange, lemon, lime, grapefruit, and tangerine. The spread of various diseases threatens the worldwide production of citrus fruit crops. Diseases such as Asiatic citrus canker, citrus tristeza virus, citrus leprosis, and especially citrus greening disease (also know [...]

by Sofía Albolafio  , María I. Gil  , Ana Allende  and Epameinondas Xanthakis

Received: 02 December 2020;  Published: 21 April 2021;  doi: 10.21926/rpm.2102013

The present study aimed to characterize wastewater fractions obtained after the wet extraction of proteins from legumes. In addition, the suitability of wastewater fractions for the potential recovery of high value-added compounds was also examined, and consequently, the prevention of the environmental impact of these wastes was explored. Similar to the industrial production of proteins, wet alkaline and acidic extractions of proteins from faba bean and pea flours were performed in two stages of extraction. The dif [...]

by Sam T Briggs  , Mary Beth B Monroe  , Mark A Weizbicki  , Sayyeda Marziya Hasan  and Duncan J Maitland

Received: 05 April 2021;  Published: 25 June 2021;  doi: 10.21926/rpm.2102025

Shape memory polymers (SMPs) are highly attractive materials for medical devices. Specifically, SMP foams are currently being used as embolic devices in peripheral and cerebral vascular applications. To ensure the proper function and safety of these materials in their intended applications, it is important to understand how processing treatments, such as aging, sterilization, and foam composition can influence their degradation. Here, SMP foams were treated with industry relevant processing parameters, and the infl [...]

by Antonio Vázquez-López  , Marina García-Carrión  , Erlend Hall  , Anisa Yaseen  , Ilknur Kalafat  , María Taeño  , Junjie Zhu  , Xinyu Zhang  , Elif Arici  , Omer Suat Taskin  , David Maestre  , Emilio Nogales  , Pedro Hidalgo  , Julio Ramírez-Castellanos  , Bianchi Méndez  , Neslihan Yuca  , Smagul Karazhanov  , Erik S. Marstein  and Ana Cremades

Received: 09 November 2020;  Published: 08 May 2021;  doi: 10.21926/jept.2102020

Hybrid composites based on inorganic nanomaterials embedded into a polymer matrix have were synthesized and characterized. Oxide semiconductor nanoparticles (SnO, SnO2, TiO2, Ga2O3, and NiO) and Si nanoparticles were employed as inorganic counterparts in the hybrid composite, while a conductive polymer (PEDOT:PSS) with diverse additives was used as the organic matrix. The composites were spin-coated on Si or glass substrates. The potential use of these materials in photovoltaic devices to improve Si surface passiva [...]

by Maria Kontodiou  , Vassilis Paspaliaris  , Themistoklis Dagklis  , Elisavet Siomou  , Ahmed Hamid Al-Rikabi  , Kalliopi Tsita  , Theano Stavroulaki  , Andreas Pampanos  , Apostolos Zavlanos  , Georgios Papaioannou  , Ioannis Papoulidis  , Loretta Thomaidis  and Emmanouil Manolakos

Received: 30 May 2018;  Published: 16 September 2018;  doi: 10.21926/obm.genet.1803035

Background: Small supernumerary marker chromosomes (sSMC) are structurally abnormal chromosomes, and their characterization exclusively by banding cytogenetics is almost impossible. Multicolor fluorescence in situ hybridization approaches for their characterization are effective but expensive and time-consuming. Recently, the application of molecular karyotyping has resulted in improving the characterization of sSMC. Methods: Molecular karyotyping was used for the identification of a sSMC in this study. Results: In [...]

by Joshua C. Brown  and Jessica L. Broadway

Received: 01 December 2020;  Published: 20 April 2021;  doi: 10.21926/obm.neurobiol.2102091

Lamotrigine is generally accepted as a well-tolerated medication with few cognitive side effects. Here, we report a case of a 62-year old female with a severe, rapidly progressive dementia-like process which was completely reversed after reduction of lamotrigine. Associated findings included hyperreflexia with clonus, ataxia, Wernicke-like dysphasia, global cognitive impairment, burst suppression on electroencephalogram (EEG), and bilateral parietal hypo-metabolism on fluorodeoxyglucose-Positron Emission Tomography [...]

by Xiuhui Tang  , Daming Zhang  and Hua Chai

Received: 19 May 2021;  Published: 08 July 2021;  doi: 10.21926/jept.2103032

In AC microgrid systems, technical issues resulting from the power control effect are the power control method efficiency and the filter resonance since voltage-frequency interference and filtering resonance may cause significant control input reduction and oscillation. A simple and robust solution is to regulate active power flow by adding an optimal passive damping resistor. The optimal LCL filter parameterization process in this paper provides an innovative approach to obtain the optimal quality factor and the o [...]

by Kate McKeown  , Emma Richards  , Jessica Richardson  and Andrea Tales

Received: 08 January 2021;  Published: 07 June 2021;  doi: 10.21926/obm.neurobiol.2102100

Information processing speed (Reaction time, RT) to a single administration of the Trails A and Trails B components of the Trail Making Test (TMT) is used in the assessment of brain and behavioural functional integrity across the lifespan in both clinical and research contexts. Although the clinical utility of such single trial-related and thus rapidly gained results, is recognised, it is possible that its administration as a single trial only, precludes its ability to provide a more in-depth and thus relevant repr [...]

by Alicia Stapp  , Madalyn Falkenheiner  and Kenya Wolff

Received: 15 November 2021;  Published: 13 January 2022;  doi: 10.21926/rpn.2201001

It is recommended that children ages 3-5 receive 180 minutes of physical activity a day, with at least 60 minutes of moderate-to-vigorous physical activity. Despite these recommendations, a majority of preschoolers are not provided opportunities in the early childhood education setting to meet these daily recommendations through either structured or unstructured physical activity. Accordingly, the number of young children identified as overweight or obese over the past couple of decades has increased. Critical to a [...]

by Jin-Ho Lee  , Florence Laure Djiki Tchetgna  , Matthias Krufczik  , Eberhard Schmitt  , Christoph Cremer  , Felix Bestvater  and Michael Hausmann

Received: 14 September 2018;  Published: 19 February 2019;  doi: 10.21926/obm.genet.1901064

Background: Fluorescence In Situ Hybridization (FISH) has become routine for bio-medical research and medical diagnosis, thereby offering a variety of probes and ready-to-use kits that fulfil requirements for many applications. However, conventional FISH relies on chemical and/or thermal denaturation to improve target accessibility and uses huge amounts of DNA that needs to be bonded to the target site. COMBinatorial Oligo-nucleotide FISH (COMBO-FISH) offers possibilities to circumvent these shortcomings. Methods: [...]

by Peter Bauer  , Gabriele Wildhardt  , Dieter Gläser  , Clemens Müller-Reible  , Hanno J. Bolz  , Hanns-Georg Klein  , Ulrich Finckh  and Ute Hehr

Received: 24 September 2017;  Published: 28 April 2018;  doi: 10.21926/obm.genet.1802019

On behalf of the German Society of Human Genetics, we present guidelines for molecular genetic diagnostic testing using high-throughput technology, such as next-generation sequencing (NGS). These guidelines have been formulated by an expert group and reviewed by members of the German Society of Human Genetics. Building on the existing EuroGentest guidelines for diagnostic NGS, these updated guidelines incorporate additional aspects and country-specific topics. New considerations include the introduction of a check [...]

by David Feinstein

Received: 01 February 2021;  Published: 19 April 2021;  doi: 10.21926/obm.icm.2102014

The impact of psychological factors on illness is, in recent years, being biochemically mapped. The subspecialties of psychosomatic medicine, health psychology, psychoneuroimmunology, and integrative medicine work with mind and body in concert to promote health and healing. A specialized set of mind-body approaches, collectively called “energy psychology,” is being utilized within these and related clinical frameworks to facilitate beneficial changes in the neurological underpinnings of (1) mental states that imped [...]

by Richard Sarnat

Received: 09 March 2018;  Published: 12 April 2018;  doi: 10.21926/obm.icm.1802003

While “miraculous healings” of various disease states have been scientifically reported previously, the exact mechanism, which allow for these seeming miracles or spontaneous remissions is poorly understood. [1,2,3,4,5,6,7,8,9,10,11,12,13,14,15] By contrast, the mechanism of action underlying the “miraculous healings” in the three case studies reported herein: Sarcoidosis, Chronic Lyme disease and Fibromyalgia seems to be understood with greater clarity, as these case reports are representative of the many hundreds [...]

by Kuok Ho Daniel Tang

Received: 16 November 2025;  Published: 19 November 2025;  doi: 10.21926/rpse.2504016

Artificial intelligence (AI) is reshaping microplastic research by enabling faster, more accurate, and scalable detection, characterization, and modeling. Deep learning automates the identification and classification of microplastics from microscopy images, while machine learning accelerates the recognition of polymers from Raman and infrared spectra. AI-based clustering and segmentation improve the analysis of complex samples, and source-apportionment models learn morphological and chemical features to trace emiss [...]

by Helena M. Minyé

Received: 06 February 2020;  Published: 18 May 2020;  doi: 10.21926/obm.neurobiol.2002057

Temporomandibular disorders (TMD) are a group of musculoskeletal and neuromuscular conditions that involve the temporomandibular joint (TMJ), the masticatory muscles, and branches of the trigeminal nerve. TMD is the most common chronic oral facial pain disorder. Pain associated with TMD can be clinically expressed as myogenous or arthrogenous in etiology. The myogenous variant of TMD is characterized by pain in the muscles of mastication. The arthrogenous form of TMD is caused by pain in the joint leading to synovi [...]

by Ana Monteagudo-Sánchez  , Marta Sánchez-Delgado  , Sonia Guara Ciurana  , Jose Medrano  , Maria Eugenia Poo-Llanillo  , Miho Ishida  , Gudrun E. Moore  , Isabel Iglesias-Platas  , Carlos Simón  and David Monk

Received: 29 May 2018;  Published: 29 July 2018;  doi: 10.21926/obm.genet.1803026

Background: Symmetrical DNA methylation profiles of autosomal genes are associated with equal expression by both alleles. Genes with an allelic imbalance or monoallelic expression are associated with discrete intervals of allele-specific methylation (ASM), as highlighted by genomic imprinting, X-chromosome inactivation and genotype-driven ASM. However, a more complex pattern has been described in which random monoallelic methylation provides cells with a unique mechanism for modulating allelic dosage. Methods: We c [...]

by Katarzyna Grubel  , Ji Su  , Jotheeswari Kothandaraman  , Kriston Brooks  , Gabor A. Somorjai  and Tom Autrey

Received: 01 September 2020;  Published: 23 November 2020;  doi: 10.21926/jept.2004016

In this perspective on hydrogen carriers, we focus on the needs for the development of robust active catalysts for the release of H2 from aqueous formate solutions, which are non-flammable, non-toxic, thermally stable, and readily available at large scales at reasonable cost. Formate salts can be stockpiled in the solid state or dissolved in water for long term storage and transport using existing infrastructure. Furthermore, formate salts are readily regenerated at moderate pressures using the same catalyst as for [...]

by Najam A. Sharif

Received: 24 January 2022;  Published: 22 March 2022;  doi: 10.21926/obm.neurobiol.2201116

Glaucomatous optic neuropathy (GON) associated with different forms of glaucoma and chronic ocular hypertension (cOHT) is characterized by progressive loss of retinal ganglion cells and their axons in the optic nerves that project to the brain to transmit visual information. The resultant thinning of the optic nerves cause loss of peripheral vision, which if not halted or slowed, can lead to irreversible blindness. Whilst the precise triggering insult(s) for the primary open angle glaucoma (POAG), the most prevalen [...]

by Jennie Cao  , Valentina L Kouznetsova  and Igor F Tsigelny

Received: 30 January 2019;  Published: 01 April 2019;  doi: 10.21926/obm.genet.1902071

Cancer is the leading cause of death in dogs, and 50 percent of dogs over the age of 10 develop cancer at some point. The most common cancers in dogs include lymphoma, mast cell tumors, osteosarcoma, mammary gland tumors, and melanoma, and many of them share marked similarities with their human counterparts. Although canines are afflicted with many of the same types of cancers as humans, the genetic basis behind these cancers are not as well understood. Thus, the aim of this study is to elucidate some of the molecu [...]

by Jordin Lane  and Kevin R. Fontaine

Received: 28 December 2020;  Published: 21 April 2021;  doi: 10.21926/obm.icm.2102015

Carbohydrate-restricted ketogenic diets (KD) were introduced in the mid-19th century as a weight loss method with a resurgence of its use in epilepsy treatment in the 1920’s. Research conducted over the last several years provides evidence that KD’s can confer beneficial effects for several chronic metabolic diseases, including obesity, type-2 diabetes, and polycystic ovary syndrome. In recent years, emerging evidence suggests KD’s may also have therapeutic benefits for some cancers and for neurological conditions [...]

by Ibikunle Olalekan OGUNDARI

Received: 08 September 2022;  Published: 03 April 2023;  doi: 10.21926/jept.2302013

This study examined the techno-economic specifications for a Waste-to-Suburban Cooking Energy critical infrastructure project in Southwestern Nigeria. Technological and project economic data for the W2E project were obtained from strategic sources and energy project foresight/analysis framework used. The results showed residential upgraded biogas-for-cooking demand of approximately 10,243 m3/month, and municipal solid waste (MSW) input of approximately 80 tonnes/month. The planned biogas plant had estimated costs o [...]

by C. Aris Chatzidimitriou-Dreismann

Received: 31 March 2020;  Published: 23 June 2020;  doi: 10.21926/rpm.2002015

Current developments of non-relativistic quantum mechanics appear to predict, and reveal, counter-intuitive dynamical effects of hydrogen in nanostructured materials that are of considerable importance for basic research as well as for technological applications. In this review, the experimental focus is on H2O and H molecules in carbon nanotubes and other nanocavities that have been experimentally investigated using the well-established technique of incoherent inelastic neutron scattering (INS). For instance, the [...]

by Kim Lawson

Received: 05 November 2019;  Published: 20 January 2020;  doi: 10.21926/obm.neurobiol.2001049

Fibromyalgia, characterised by persistent pain, sleep disturbance, fatigue and cognitive dysfunction, is a central sensitivity syndrome that also involves abnormality in peripheral generators and in the hypothalamic pituitary adrenal axis. Heterogeneity of clinical expression of fibromyalgia with a multifactorial aetiology has made the development of effective therapeutic strategies challenging. Non-restorative sleep associated with poor sleep quality is a characteristic of fibromyalgia which is linked to symptom s [...]

by Maathar Al Qasimi  , Dhafer Manna Al Zulayqa  and Mostafa Seifan

Received: 29 July 2020;  Published: 23 October 2020;  doi: 10.21926/rpm.2004022

Additive manufacturing is a recent revolution in the construction field since cementitious materials became printable. This extrusion technique has enabled the construction of very complex geometry with a reduction in costs, time and labour interventions. This study aims to evaluate the possibility of reinforcing 3D printable cementitious composites with the use of nano and micro materials, particularly nano silica, micro silica and microfibrillated cellulose (MFC) which are known for their ability to enhance the f [...]

by Carsten Unglaub  , Johannes Thiessen  and Andreas Jess

Received: 27 September 2022;  Published: 03 January 2023;  doi: 10.21926/cr.2301001

Fischer-Tropsch reactors operated in a steady state suffer from a low pore effectiveness factor and a high methane selectivity caused by internal mass transfer limitations due to the accumulation of long-chain hydrocarbons inside the catalyst pores. Therefore, an alternating process switching between Fischer-Tropsch synthesis (FTS) and drainage of the pores by hydrogenolysis is proposed. The periodical cracking of the accumulated waxes within the (partially) filled pores, realized by a switch from syngas (H2, CO) t [...]

by Robert B. Diller  , Robert G. Audet  , Mediha Gurel  , Eric E. Lee  , Aaron J. Tabor  , Peter McFetridge  and Robert S. Kellar

Received: 25 September 2019;  Published: 09 June 2020;  doi: 10.21926/obm.transplant.2002112

Mesenchymal Stromal/Stem Cells (MSCs) were originally discovered in the 1970s. MSCs are considered a multipotent population that retain tri-lineage differentiation. These cells can be sourced from a variety of tissues, including bone marrow, adipose, molar pulp, and birth tissues. Historically varying definitions of MSCs have existed, but in 2006, the International Society for Cellular Therapy (ISCT) set forth a standardized, minimal criteria for MSCs, including plastic adherence, differentiation into osteoblasts, [...]

by Adefemi Adebisi Alade  and Ahmed Ibrahim

Received: 22 September 2022;  Published: 09 January 2023;  doi: 10.21926/rpm.2301003

Performance evaluations of wood and other lignocellulosic-based composites involve complex scenarios of several factors such as material heterogeneity and geometry that often leads to complicated, expensive, and time-consuming experimental procedures. Hence, the application of computational modeling and simulation is desirable to mitigate these biocomposites’ performance testing challenges. This review paper, therefore, presents an outlook on the finite element method (FEM) application in probing performance charac [...]

by Misirkhan A. Talybov  , Lala A. Azizova  and Ilmutdin M. Abdulagatov

Received: 24 September 2019;  Published: 24 December 2019;  doi: 10.21926/jept.1904006

Background: In the present study, vapor-pressures of three geothermal fluids from Baden-Baden geothermal field (Kirchenstollen, Friedrichstollen, and Murquelle, southeastern region of Germany) were measured over the temperature range of 274-413 K. The combined expanded uncertainty of the temperature and vapor-pressure measurements at 95% confidence level with a coverage factor of k = 2 were estimated to be 0.01 K and 1-3 Pa at low and 10-30 Pa at high temperatures, respectively. The measured values of vapor-pressur [...]

by Elissavet Feloni  and Evgenia Karandinaki

Received: 08 May 2021;  Published: 17 August 2021;  doi: 10.21926/jept.2103039

The objective of this study is the development and implementation of a geographic information system (GIS)-based methodology to determine suitable sites for wind farms by using multicriteria decision making (MCDM) techniques. Many eligibility criteria are considered in this approach, such as GIS analysis is performed in combination with MCDM techniques, both for the criteria weighting process (using the analytical hierarchical process) and for the standardization/classification of the criteria values into a common [...]

by Daniela Litscher  and Gerhard Litscher

Received: 24 May 2016;  Published: 17 August 2016;  doi: 10.21926/obm.icm.1601002

The present report deals with some current important aspects of traditional Chinese medicine (TCM) education and practice in Europe and China. The data and facts are based on a lecture of one of the authors (G.L.) prepared for a conference in Wuhan about acupuncture education in Europe, and lectures of two high-ranking representatives of renowned Chinese institutions (State Administration of TCM and Heilongjiang University of Chinese Medicine, Harbin). In addition to current figures regarding TCM in general, the ad [...]

by Malith Kadirappulli-Hewage  and Rasika Jayasekara

Received: 30 August 2019;  Published: 02 January 2020;  doi: 10.21926/obm.geriatr.2001096

Social isolation and social disconnectedness have resulted in some older adults ending their lives by suicide; therefore, improving social connectedness has become an integral part of suicide prevention programmes. The purpose of this literature review was to assess the impact of social connectedness interventions for preventing suicide in older adults. It is evident that interventions aimed at promoting social connectedness are intended to alleviate stress and depressive symptoms due to social separation and traum [...]

by Elizabeth Orsega-Smith  , Stephen Goodwin  , Melissa Ziegler  , Katie Greenawalt  , Jennie Turner  and Erica Rathie

Received: 31 October 2018;  Published: 10 January 2019;  doi: 10.21926/obm.geriatr.1901029

Background: Research has shown that positive psychology interventions can enhance subjective well-being and reduce depression. However, the efficacy of these programs with older adult populations has been minimally studied. The present study studied the short and long term impact of an intervention enhancing happiness and overall mental well-being in older adults. Methods: The Art of Happiness is an 8-week program conducted at 2 senior centers in the state of Delaware. Each 90-minute class examined a different topi [...]

by Alberto Arias-Pérez  , Daniel Ramírez-Torres  , María E. Rodríguez  , Silvia Portela-Bens  , Emilio García-Suarez  , Manuel A. Merlo  , Aglaya García-Angulo  , Ismael Cross  , Thomas Liehr  and Laureana Rebordinos

Received: 31 July 2018;  Published: 24 October 2018;  doi: 10.21926/obm.genet.1804044

Background: MicroRNAs (miRNAs) are small, non-coding RNAs that play a very important role in gene expression by regulating mRNA cleavage and translation. The Senegalese sole, Solea senegalensis (Kaup 1858), is a flatfish species that shows great potential for marine aquaculture. Nevertheless, the existence of sexual dysfunction of males reared in captivity, high larval mortality, and diseases have hampered its production. The integration of sequence information with data on chromosomal physical location is useful f [...]

by John Old  and Cornelis Harteveld

Received: 03 July 2017;  Published: 14 August 2017;  doi: 10.21926/obm.genet.1703005

Carrier screening for the haemoglobinopathies has undergone many technological improvements in haematological and molecular diagnostic techniques since the first prenatal diagnoses by DNA analysis in the 1970s by Southern blot analysis enabled the implementation of effective successful prevention programmes for beta thalassaemia involving public education, carrier screening, genetic counselling and prenatal diagnosis in Mediterranean countries. The application of a wide variety of PCR-based molecular diagnostic tec [...]

by Jonathan Manh Dang  , Luma Bashmi  , Stephen Meeneghan  , Janet White  , Rebecca Hedrick  , Jelena Djurovic  , Brigitte Vanle  , Dennis Nguyen  , Jonathan Almendarez  , Paula Ravets  , Yasmine Gohar  , Sophia Hanna  , Itai Danovitch  and Waguih William IsHak

Received: 28 March 2018;  Published: 25 June 2018;  doi: 10.21926/obm.icm.1802011

Background: An increasing number of patients and practitioners are using mindfulness meditation programs despite uncertainty about the evidence supporting these programs’ health benefits. Aim: To review the current evidence on the effectiveness of mindfulness-based interventions (MBI) on depressive symptoms and quality of life (QOL) among patients with depression comorbid medical conditions and those with major depressive disorder. Methods: A comprehensive search of PubMed, Ovid MEDLINE, and PsycINFO was performed [...]

by Christopher Igwe Idumah  , Ifeanyi Emmanuel Okoye  and Chioma Joan Ikebudu

Received: 05 September 2024;  Published: 02 February 2025;  doi: 10.21926/rpm.2501005

3-Dimension printing (3-DPT) or additive manufacturing (AM) technology has been utilized for a while in the construction of customized 3-D objects utilizing computer software such as computer-aided design (CAD). However, the emergence of an innovative and new four-dimensional printing (4-DPT) has enabled the synergy of AM technology with programmable materials in transforming digital processes virtually into physical entities, thereby providing innovation and advanced functionalities. 4-DPT is a procedure facilitat [...]

by Mariana P. Koss  and Luiz E. M. Lima

Received: 14 February 2022;  Published: 24 May 2022;  doi: 10.21926/jept.2202019

In gas-liquid flows, droplets that detach from the liquid film lining the internal walls of a pipe and merge with the gas flowing through the pipe follow an annular flow pattern. This work analyzes correlations for estimating the entrainment fraction of such droplets contained in the literature by comparing their predictions with experimental data also from the literature. The results of this comparative study demonstrate that the analyzed correlations do not accurately reproduce experimental conditions. This is du [...]

by Ugo Chiocchini  and Giovanni Savarese

Received: 14 May 2019;  Published: 05 September 2019;  doi: 10.21926/jept.1903003

Background: The Regione Lazio-Direzione Regionale dello Sviluppo Economico e delle Attività Produttive (RL–DRSEAP), carrying out its public functions to govern the use of mineral resources (including thermal water), planned the exploitation of the Viterbo hydrothermal system on the basis of a conceptual hydrogeological model (CHM). The CHMs of the Viterbo area and that of the neighboring Tuscany region, characterized by the same geological and hydrogeological setting, are discussed, suggesting the unreliability of [...]

by Harry G. Hong

Received: 10 December 2018;  Published: 25 March 2019;  doi: 10.21926/obm.icm.1901019

Background: Electrodermal measurement of acupuncture points has been correlated to physiologic and pathologic conditions with clinical and laboratory studies. Emerging evidence indicates that in addition to therapeutic effect, acupuncture points may also have diagnostic properties. However, physiologic basis of this phenomenon is still unknown. Objective: To determine how electrodermal activity of acupuncture points on hands and feet responds to exercise-induced sympathetic stress and how electrodermal measurement [...]

by Maria Neve Ombra  , Filomena Nazzaro  and Florinda Fratianni

Received: 30 March 2023;  Published: 07 June 2023;  doi: 10.21926/rpn.2302008

Edible wild plants are a largely available food at no cost and an emblem of sustainability. Among the numerous varieties of edible wild plants, purslane (Portulaca oleracea L.) and common mallow (Malva sylvestris L.) are good sources of healthful bioactive compounds. Therefore, there is a growing interest in their consumption for health-related nutritional and sustainable perspectives. Fresh durum wheat tagliatelle fortified with dried and pulverized leaves of mallow or purslane at two distinct percentages of integ [...]

by Rachel Mills  , Louisa Jackman  , Mithila Mahesh  and Ian James

Received: 12 December 2018;  Published: 11 February 2019;  doi: 10.21926/obm.geriatr.1901032

Background: Research suggests that the use of lies and deception is prevalent within dementia care settings, despite ongoing debates raised about the ethics of this approach. There has been increasing exploration of when and why deceptive practices should be used, but the lack of clarity as to what constitutes a lie has caused difficulty in ensuring that lies are used ethically. The aim of this study was to widen our understanding of the key dimensions that underpin the use of lies, and further to use this informat [...]

by Mieczysław Szyszkowicz

Received: 14 April 2021;  Published: 10 June 2021;  doi: 10.21926/aeer.2102014

Each country has its own characteristics of COVID-19 infection trajectory and epidemic waves. Differences in government-implemented restrictions and social regulations result in variability of the virus transmissions and spread dynamics. This in turn results in various shapes of the growth function used to represent and describe the propagation of infection. Statistical methods are applied to fit non-linear functions to represent daily time-series data of the cumulative numbers of COVID-19 cases. The aim of this wo [...]

by Suzie Jokic  , Nicole Jacqueline Albrecht  and Sue Erica Smith

Received: 15 July 2018;  Published: 23 January 2019;  doi: 10.21926/obm.icm.1901004

Background: Adult learners often engage in formal education because they want to create changes in their lives and are determined to succeed in their chosen field. However, they also come with emotional "baggage" of early educational experiences, frequently have to deal with a multitude of competing demands, have financial strain, may face a lack of support, illness and/or injury. In addition, they are often dealing with the challenges of unfamiliar academic work, competing deadlines and initially lack basic academ [...]

by Masoume M. Raeissi  and Rob Knapen

Received: 07 April 2025;  Published: 12 August 2025;  doi: 10.21926/aeer.2503028

Environmental science addresses critical global challenges, including climate change, biodiversity loss, and sustainability. These complex topics generate a vast amount of both structured and unstructured data, from remote sensing output to policy documents, guidelines, and scientific literature. Effectively processing and utilizing this information is essential for advancing research and supporting decision-making. Large Language Models (LLMs) have shown remarkable capabilities in natural language understanding an [...]