Table of Content

Open Access Original Research

The Daclatasvir/Asunaprevir/Beclabuvir Combination Therapy for Chronic Hepatitis C Patients Experiencing Failure of IFN-Free DAA-Based Therapies

Received: 29 September 2019;  Published: 17 December 2019;  doi: 10.21926/obm.hg.1904041

Abstract

Background: Daclatasvir/asunaprevir/beclabuvir (DCV/ASV/BCV) combination therapy had been available for the treatment of chronic hepatitis C patients with genotype 1 (CHG1) in Japan. Our aim was to report the efficacy and safety of DCV/ASV/BCV in patients experiencing treatment failure with interferon (IFN)-free direct-acting antiviral agent (DAA)-based therapies, which have not been fully evaluated. Methods: We evaluated the efficacy and safety of 12-week DCV/ASV/BCV combination therapy for CHG1 patients experien [...]

1320 7990

Open Access Editorial

Epigenetics is Here to Stay

Received: 24 April 2019;  Published: 30 April 2019;  doi: 10.21926/obm.genet.1902075

Abstract

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1464 7987

Open Access Review

Emerging Advances in 3-D & 4-D Printing of Polymeric Nanoarchitectures & Multifacet Applications

Received: 05 September 2024;  Published: 02 February 2025;  doi: 10.21926/rpm.2501005

Abstract

3-Dimension printing (3-DPT) or additive manufacturing (AM) technology has been utilized for a while in the construction of customized 3-D objects utilizing computer software such as computer-aided design (CAD). However, the emergence of an innovative and new four-dimensional printing (4-DPT) has enabled the synergy of AM technology with programmable materials in transforming digital processes virtually into physical entities, thereby providing innovation and advanced functionalities. 4-DPT is a procedure facilitat [...]

2190 7987

Open Access Original Research

Geochemical Assessment of the Modern Sediments of a Lake in the North of Russia

Received: 09 March 2023;  Published: 05 July 2023;  doi: 10.21926/aeer.2303038

Abstract

Core sediment (sapropel) samples were collected from Lake Okunozero, the Republic of Karelia, Russia, to assess the distribution of heavy metals and their main fractions, probable sources of pollution, and potential ecological and toxicological risks for the water body. Heavy metal concentrations were measured by the mass spectrometry method using an XSeries-2 ICP-MS. The sequential extraction of heavy metals from sapropel samples was performed using the scheme of Tessier. According to the Russian Interstate Standa [...]

1244 7984

Open Access Research Article

Finding Positives Amidst the Negatives: A Thematic Analysis of the Impact of the COVID-19 Pandemic on Canadians 55+

Received: 31 July 2022;  Published: 17 November 2022;  doi: 10.21926/obm.geriatr.2204213

Abstract

Disasters such as the COVID-19 pandemic exact a toll on vulnerable populations in terms of morbidity and mortality, but they also provide opportunities for personal growth and development and demonstration of personal and collective resiliency. This inductive thematic analysis explores self-perceived negative and positive impacts of the COVID-19 pandemic on 2994 Canadians aged 55+. Data derive from response to two open-ended questions included in a national online survey (View Survey (sfu.ca)) conducted between Aug [...]

967 7979

Open Access Original Research

Mesoscale Modeling of Extrusion and Solidification During Material Extrusion Additive Manufacturing

Received: 22 August 2023;  Published: 25 October 2023;  doi: 10.21926/rpm.2304033

Abstract

In this work, we apply a multiphysics approach to fused deposition modeling to simulate extrusion and solidification. Restricting the work to a single line scan, we focus on the application of polylactic acid. In addition to heat, momentum and mass transfer, the solid/liquid/vapor interface is simulated using a front-tracking, level-set method. The results focus on the evolving temperature, viscosity, and volume fraction and are cast within a set of parametric studies, to include the printing and extrusion speed, a [...]

1532 7978

Open Access Original Research

Nature and City Sounds Influence Physiological and Psychological Markers in College Students

Received: 02 March 2023;  Published: 28 September 2023;  doi: 10.21926/obm.icm.2303039

Abstract

Worldwide, human population growth has led to a higher demand for urbanization. While this development is in accordance with our gregarious lifestyles, our availability and contact with nature has consequentially been minimized. The goal of this study was to evaluate whether sounds from nature versus urban environments affect vital signs (i.e., heart rate and respiration rate) and mood states of female college students. Emotional states were assessed using the Positive and Negative Affect Schedule (PANAS) questionn [...]

1377 7971

Open Access Original Research

Thermodynamic and Structural Optimization of Organic Rankine Cycle Plant for Clean Energy Access Using Artificial Bee Colony and Multi-Criteria Decision-Making Algorithms

Received: 29 December 2022;  Published: 13 April 2023;  doi: 10.21926/jept.2302015

Abstract

The quest to decarbonize the energy space to avert the negative climate change consequences calls for using low/zero-carbon energy conversion technologies in the energy generation space. The Organic Rankine Cycle is a low/zero-carbon energy conversion technology for recovering waste heat from low to medium-temperature heat sources and for biomass conversion. Therefore, this paper presents the thermodynamic optimization, with an artificial bee colony algorithm, of different ORC configurations, including simple organ [...]

1535 7969

Open Access Review

Quantum Semiconductors Based on Carbon Materials for Nanophotonics and Photonics Applications by Electron Shuttle and Near Field Phenomena

Received: 16 September 2023;  Published: 26 December 2023;  doi: 10.21926/rpm.2304037

Abstract

This review intended to resume key Research reports and publications that open many themes and topics related to Carbon-based semiconductors and Quantum emitters. The Design and synthesis of highly pure materials such as Graphene, Carbon Nanotubes, fullerenes, and other Carbon-based allotropes were shown. They presented their most important and promising properties concerning new studies and developments in photonics. Carbon-based Quantum dots, semiconductors, and higher sized Nanoplatforms allowed us to discuss fu [...]

1102 7967

Open Access Case Report

Pneumocystis jirovecii pneumonia Suspected Due to Low-Dosage Prednisolone Treatment for Acute Autoimmune Hepatitis: Case Report and Literature Review

Received: 16 November 2016;  Published: 21 January 2017;  doi: 10.21926/obm.hg.1701001

Abstract

(1) Background: Preventative treatment for Pneumocystis jirovecii pneumonia (PCP) has been recommended for patients receiving ≥20 mg/day prednisolone. We describe a patient who developed PCP while receiving a dose of 15 mg/day prednisolone, and consider criteria for the initiation of preventative therapy for PCP in patients with autoimmune hepatitis (AIH) treated with prednisolone. (2) Case Report: A 71-year-old woman initially possessed dark-colored urine, white stool, and decreased appetite, which indicated hepat [...]

1250 7961

Open Access Original Research

The Relationship between Anger, Stress, Psychological Distress and Mood Disorders among Entrepreneurs

Received: 18 December 2024;  Published: 26 May 2025;  doi: 10.21926/obm.neurobiol.2502288

Abstract

The present study investigates the association between anger, stress, psychological distress and mood disorders among Egyptian entrepreneurs. Approach-wise, the study is quantitative, and its cross-sectional data were collected using a questionnaire. The study’s respondents are Egyptian entrepreneurs involved in several business activities. Hence, the study concluded based on 286 valid responses. We used analysis of moment structures (AMOS) software, where we conducted path analysis to conclude the results. C [...]

1129 7955

Open Access Original Research

Integrated Web Application (Snips2HLA-HsG) Development for Sample Preparation and Model Creation for HLA Allele Prediction with the SNP Data Using HIBAG Package of Bioconductor and R Programming

Received: 24 December 2023;  Published: 14 June 2024;  doi: 10.21926/obm.genet.2402243

Abstract

The present study introduces Snips2HLA-HsG, an integrated application designed for SNP genotype analysis and HLA allele type prediction. Leveraging attribute bagging, a powerful ensemble classifier technique from the Bioconductor HIBAG package, Snips2HLA-HsG offers a comprehensive response for genetic analysis. Accessible via https://snips2hla.shinyapps.io/hla_home/, the application distinguishes itself by prioritizing user-friendliness and integrating all-purpose functionalities, including sample preparation, mode [...]

1087 7954

Open Access Research Article

Neuroprotective (Antioxidant, Antiamyloidogenic, and Antiexcitatory) Effects of Trévo™ against Cadmium Chloride Neurotoxicity in Adult Male Wistar Rats

Received: 29 May 2022;  Published: 26 September 2022;  doi: 10.21926/obm.neurobiol.2203135

Abstract

Cadmium (Cd) is a heavy metal that is deleterious to brain development as it increases brain aging. Trévo is a multi-herbal supplement that provides various health benefits, including boosting the immune system and detoxification. In this study, we investigated the neuroprotective effects of Trévo against the neurotoxic effects of cadmium chloride (CdCl2). Thirty male Wistar rats were equally divided into three groups: Group I (normal control), Group II (administered CdCl2), and Group III (administered Trévo and Cd [...]

1022 7952

Open Access Original Research

Normal Saline vs Plasma-Lyte A Use Intra- and Post-Operatively in Adult Kidney Transplant Recipients

Received: 13 February 2023;  Published: 18 April 2023;  doi: 10.21926/obm.transplant.2302181

Abstract

Fluid management intra- and post-operatively for kidney transplant recipients (KTR) is essential to maintain adequate perfusion to the kidney. 0.9% normal saline (NS) is commonly used, but it can cause hyperchloremic metabolic acidosis, which may result in hyperkalemia and lead to delayed graft function (DGF). Plasma-Lyte A (PA) is an alternative option that has a lower amount of chloride and a neutral pH, which may offset the risk of hyperkalemia. The aim of this study is to determine the incidence of DGF in KTRs [...]

1147 7944

Open Access Research Article

Permeability, Compressibility and Pressure Prediction in Supercharged Wireline and FTWD Environments

Received: 12 April 2023;  Published: 10 July 2023;  doi: 10.21926/jept.2303023

Abstract

In conventional wireline and LWD/MWD formation testing, downhole predictions for rock and fluid properties are based on simplified Darcy flow models, but only for mathematical expediency. These require initially constant pressures that are uniform throughout the reservoir. This limitation precludes common applications in overbalanced drilling, so that supercharge or near-well invasion effects - associated with rapidly decreasing pressures at the sandface where pressures are measured - are completely ignored. Such 1 [...]

1459 7943

Open Access Concept Paper

Using Elder Abuse Case Studies to Develop LGBTQ+ Cultural Competency

Received: 16 July 2023;  Published: 15 January 2024;  doi: 10.21926/obm.geriatr.2401266

Abstract

Lesbian, gay, bisexual, transgender, and queer (LGBTQ+) elders are vulnerable to both the “usual” types of elder abuse (physical, sexual, emotional, and financial abuse, along with neglect), and with abuse that is specific to the context and history of LGBTQ+ elders. Training for adult protective services, long-term care ombudsmen, and other professionals who work with abused elders therefore should include information and skill-building in responding to this population. Research into effective training about LGBTQ [...]

1461 7940

Open Access Technical Note

Successive Detection of Telomerase by IHC and Assessment of Telomere Length by Q-FISH in Paucicellular Cumulus Samples from Cumulus-Oocyte Complexes Obtained in Assisted Reproduction Programs

Received: 13 May 2022;  Published: 23 September 2022;  doi: 10.21926/obm.genet.2203164

Abstract

This paper suggests an approach for the use of a single paucicellular histological sample to investigate two characteristics indicative of the cell’s functional potential: 1) the content of telomerase reverse transcriptase (TERT) and 2) the telomere length. An algorithm has been suggested for the successive detection of the catalytic telomerase subunit with immunohistochemical staining and assessment of telomere length with Q-FISH on the same set of cells. The described approach uses three incontestable advantages [...]

1266 7922

Open Access Research Article

The Complete Chloroplast Genome Sequence of Actinidia arguta var. purpurea

Received: 16 October 2023;  Published: 24 November 2023;  doi: 10.21926/obm.genet.2304203

Abstract

In this study, we report the complete chloroplast genome of Actinidia arguta var. purpurea. The chloroplast genome is 157,369 bp long as the circular (GC ratio is 37.22%). It has four subregions: a large single-copy (LSC) region of 88,609 bp, a small single-copy (SSC) region of 20,470 bp, and two inverted repeat regions (IRs) of 24,145 bp in each. The chloroplast genome of A. arguta var. purpurea contains a total of 113 unique genes, which are 79 protein-coding genes, 4 rRNA genes, and 3 [...]

1696 7921

Open Access Original Research

The Significance of Key Proteins in the RAS Signaling Pathway: Implications for Cancer and Therapeutic Targets

Received: 18 January 2024;  Published: 24 May 2024;  doi: 10.21926/obm.genet.2402236

Abstract

The RAS signaling pathway is a crucial cell transduction pathway central to transmitting signals from outside the cell to the cell nucleus and influencing fundamental biological mechanisms like cell growth, division, and specialization. This signaling pathway has recently received much attention in scientific research because of its involvement in various diseases, especially carcinogenesis. Our study identified the significance of crucial proteins in the RAS signaling cascade in cancer development and progression. [...]

1169 7900

Open Access Original Research

A Clinical Validity-Preserving Machine Learning Approach for Behavioral Assessment of Autism Spectrum Disorder

Received: 31 May 2022;  Published: 30 September 2022;  doi: 10.21926/obm.neurobiol.2203138

Abstract

Autism spectrum disorder (ASD) is a neuropsychiatric disorder associated with critical challenges related to social, communication, and behavioral issues. Recent studies have proposed machine learning (ML) techniques for rapid and accurate assessment of ASD. However, the mismatch between the ML techniques and the clinical basis of ASD assessment reduces the effectiveness of ML-based assessment tools. The present study proposed an approach that utilized the potential of ML modeling and preserved the clinical relevan [...]

1474 7899

Open Access Research Article

Intrinsic Lexical Intentionality and the Mathematics of Homomorphism

Received: 28 August 2022;  Published: 01 February 2023;  doi: 10.21926/obm.neurobiol.2301152

Abstract

Moisl [1, 2] proposed a model of how the brain implements intrinsic intentionality with respect to lexical and sentence meaning, where 'intrinsic' is understood as 'independent of interpretation by observers external to the cognitive agent'. The discussion in both was mainly philosophical and qualitative; the present paper gives a mathematical account of the distance structure preservation that underlies the proposed mechanism of intrinsic intentionality. The three-layer autoassociative multilayer perceptron (aMLP) [...]

1133 7894

Open Access Original Research

The Effect of Rake Angle and Cutting Edge Radius on the Orthogonal Cutting Process of Ti6Al4V Alloy

Received: 23 February 2024;  Published: 18 June 2024;  doi: 10.21926/rpm.2402013

Abstract

This paper investigates the effect of rake angle, α, cutting edge radius, r, and feed rate, f, on the cutting force and cutting zone temperature during orthogonal dry cutting of Ti6Al4V. A numerical model representative of the 2D orthogonal cutting process is developed using ABAQUS/Explicit software. Johnson-Cook, (JC) constitutive material model is used to describe material plasticity. JC damage model and energy-based fracture criterion are used to describe damage initiation and evolution. Using Minitab-19 softwar [...]

1382 7889

Open Access Research Article

Factor Structure of ASD Symptoms in Russian 3-4-Year-Olds

Received: 08 June 2023;  Published: 19 October 2023;  doi: 10.21926/obm.neurobiol.2304190

Abstract

The study aims to reveal autism vectors that are inherent in 3-4-year-olds with ASD. Three hundred eighty-three children with ASD took part in the research. An online questionnaire developed earlier by our research group was used. In the first stage, with the repeated use of exploratory factor analysis, the task of identifying the simplest factor structure was solved. As a result, a 7-factor system was obtained, including from 9 to 14 items in each factor (78 items in total): 1) "Persistence on sameness" (Sam); 2) [...]

1440 7882

Open Access Research Article

Carbon Taxation as An Instrument to Promote Wildfire Prevention and Avoid Biodiversity Loss in Portugal: An Order of Magnitude Analysis

Received: 09 September 2022;  Published: 15 December 2022;  doi: 10.21926/aeer.2204051

Abstract

Climate change is one of the main challenges of the current century. Emissions taxes are one of the proposed ways to help in addressing this issue. In this sense, Portugal has introduced an Addition Tax on Carbon Emissions through Law N. 82-D/2014. One of the most notorious impacts of climate change in the country is the wildfires increasing in frequency and intensity. Forests provide various ecosystem services not valued by traditional markets, such as carbon sequestration. Recently, Portugal has created new envir [...]

1896 7880

Open Access Original Research

One Week of Continuous Anesthesia by Propofol (2,6-Diisopropylphenol) Does Not Cause Neurobehavioral Changes after Recovery in the Mexican Axolotl Salamander

Received: 07 March 2022;  Published: 06 July 2022;  doi: 10.21926/obm.neurobiol.2203127

Abstract

The Mexican axolotl salamander is an important model species in regenerative medical research and experiments involving this species often require anesthesia which is usually limited to the duration of the surgical procedure or other interventions, usually lasting no more than a few hours. This study aimed to examine the potential for increasing the duration of anesthesia by continued propofol infusion for a week. Neurobehavioral changes in response to prolonged anesthesia were evaluated after two and seven days of [...]

1255 7878

Open Access Case Report

Primary Pancreatic-Type Acinar Cell Carcinoma of Jejunum Arising from Ectopic Pancreas with Synchronous Metastasis to Left Adrenal Gland

Received: 08 July 2019;  Published: 28 October 2019;  doi: 10.21926/obm.hg.1904038

Abstract

Background: Pure pancreatic-type ACC outside the pancreas is extremely rare. Methods: We presented a very rare case of primary ACC of the pancreatic-type involving jejunum with a synchronous metastasis to left adrenal gland arising in well-developed ectopic pancreas which had fully developed pancreatic acini, islets of Langerhans, ductal structures, pancreatic cancer precursor lesions and a well-formed minor papilla that opens to the mucosal surface of jejunum. We also reviewed all 21 cases of pure pancreatic-type [...]

1496 7875

Open Access Original Research

The Effect of the Addition of Titanium Dioxide on Silicone Self-Adhesive Tapes

Received: 29 February 2024;  Published: 13 May 2024;  doi: 10.21926/jept.2402012

Abstract

The investigation aimed to delve into the intricate relationship between the presence of titanium dioxide and the resulting alterations in the adhesive's behavior under different conditions. The focus extended beyond mere observation to understand how these additives interact with the adhesive matrix, potentially imparting beneficial attributes. Notably, the study delved into the optimization of thermal stability, the extension of the adhesive's functional lifespan, and the mitigation of shrinkage tendencies. This [...]

1225 7873

Open Access Review

Classical and Non-Classical Neural Communications

Received: 13 April 2023;  Published: 27 August 2023;  doi: 10.21926/obm.neurobiol.2303181

Abstract

This review was constructed to show how the connectome has evolved in motor command systems from simple command elements to complex systems of neurons utilizing parallel distributed processing and the possibility of quantum entanglement between groups of neurons. Scientific and medical interest in neural pathways and their connections have driven neuroscience and brain research for many decades so that specific systems and their feedback loops have been considered in detail. We review motor command systems in inver [...]

1294 7873

Open Access Original Research

The Importance of Specialized Inpatient Medical Stabilization for Weight Restoration of Individuals with Extreme Eating Disorders

Received: 19 December 2024;  Published: 23 May 2025;  doi: 10.21926/rpn.2502012

Abstract

Inpatient care is a significant contributor to the health-care costs associated with the treatment of individuals with eating disorders (EDs). This study seeks to better understand the treatment outcomes of individuals with extreme EDs requiring inpatient medical stabilization at specialized medical versus nonspecialized medical units. Patients transferred via air ambulance to ACUTE Center for Eating Disorders and Severe Malnutrition (specialized care) from an outside hospital (nonspecialized care) between January [...]

912 7872

Open Access Original Research

Improving the Engine Efficiency Using a New Combined Refrigeration Cycle for Low-Temperature Heat Source (Waste Heat Recovery)

Received: 19 April 2022;  Published: 08 June 2022;  doi: 10.21926/jept.2202020

Abstract

Passenger and commercial internal combustion engines have relatively large dissipated thermal energy sources that can be used for initiating thermodynamic refrigeration cycles at low temperatures while improving engine efficiency. Researchers have focused on combined power-refrigeration cycles in past studies. This paper presents the operation and performance of a new combined refrigeration system driven by waste heat recovery within the internal combustion engines. For this purpose, the effects of several paramete [...]

1345 7864

Open Access Original Research

The Unexpected Synthesis of a New (μ2-hydroxo-μ2-peroxo) Dicobalt Complex

Received: 26 July 2020;  Published: 07 September 2020;  doi: 10.21926/acr.2003008

Abstract

The compound, [cis-dichloro-(tris-2-amino(ethylamine))cobalt(III)]chloride hydrate, [cis-Cl2-(tren)Co(III)Cl]·H2O, a conglomerate crystallizing in P21 with Z = 4 (Z’ = 2), has been used as a precursor in the synthesis of a new dicobalt(III) peroxo complex: [(μ2-hydroxo)(μ2-peroxo)bis(tris-2-amino(ethylamine))di-cobalt(III)] tris(triiodide) dihydrate. This material crystallizes, without disorder, in space group P212121 with Z = 4 (Z’ = 2), thus making it, unambiguously, an example of a conglomerate. Its cell constan [...]

1573 7861

Open Access Original Research

Barriers and Facilitators to Meditation: Empirical Research Qualitative

Received: 13 March 2025;  Published: 23 June 2025;  doi: 10.21926/obm.icm.2502026

Abstract

This study aims to investigate the barriers and facilitators to meditation in the general population. This research is significant because understanding these factors can inform the design of more effective public mental health interventions and support the integration of meditation into daily life. A qualitative thematic analysis was conducted on the qualitative component of wider survey responses. Participants were recruited from MeditationHQ, which offers weekly group meditation sessions on beaches around Austra [...]

1827 7860

Open Access Interview

An Interview with Prof. Peter Schemmer

Received: 16 May 2022;  Published: 18 May 2022;  doi: 10.21926/obm.transplant.2202159

Abstract

InterviewAn Interview with Prof. Peter SchemmerOBM Transplantation Editorial OfficeLIDSEN Publishing Inc., 2000 Auburn Drive, One Chagrin Highlands, Suite 200, Beachwood, OH, USA; E-Mail: transplantation@lidsen.com OBM Transplantation2022, volume 6, issue 2doi:10.21926/obm.transplant.2202159Received: May 16, 2022Accepted: May 17, 2022Published: May 18, 2022

945 7856

Open Access Review

Cardiovascular Comorbidities and Cognitive Impairment

Received: 23 August 2022;  Published: 23 November 2022;  doi: 10.21926/obm.geriatr.2204214

Abstract

Various grades of cognitive impairment generally occur in older adults over the age of 55, where cardiovascular risk factors such as diabetes and/or hypertension, coronary artery disease, or cerebrovascular accidents are also common. Cognitive impairment occurs in various forms, from mild or amnesia such as forgetting today's date to more ominous and progressive forms, such as frank dementia. Over 5 million people worldwide suffer from dementia, most of whom live in low- and middle-income countries. It has been env [...]

1129 7841

Open Access Original Research

Quantum and Component Analysis of P3a and P3b from Auditory Single Trial ERPs Differentiates Borderline Personality Disorder from Schizophrenia

Received: 09 April 2023;  Published: 13 July 2023;  doi: 10.21926/obm.neurobiol.2303174

Abstract

Traditional approaches to EEG modelling use the methods of classical physics to reconstruct scalp potentials in terms of explicit physical models of cortical neuron ensembles. The principal difficulty with such approaches is that the multiplicity of cellular processes, with an intricate array of deterministic and random influencing factors, prevents the creation of consistent biophysical parameter sets. An original, empirically testable solution has been achieved in our previous studies by a radical departure from [...]

1287 7840

Open Access Review

Nanomedicine: Pioneering a New Frontier in Neuro-Ophthalmology

Received: 23 April 2024;  Published: 29 August 2024;  doi: 10.21926/rpm.2403022

Abstract

Nanotechnology is one of the most promising fields of study, and it represents a pioneering leap in science and technology by the precise control over materials at the atomic and molecular level. This transformation affects numerous aspects of modern human life, including medicine, healthcare, electronics, computing, and energy storage. Nanotechnology has shown significant advancements in managing various health problems through different nano-formulations. These engineered nano-systems can be used as drug delivery [...]

1640 7822

Open Access Review

Advancing Objective Pain Measurement: Exploring the Potential of Electroencephalography Biomarkers

Received: 26 February 2025;  Published: 05 August 2025;  doi: 10.21926/obm.neurobiol.2503296

Abstract

Chronic pain involves complex cortical and subcortical changes, suggesting that brain electrical activity may be a potential biomarker for nociceptive processing. Pain leaves its signature in the brain's oscillatory patterns, yet limited studies have explored the neurophysiological alterations associated with chronic pain. This review examines the pain detection method currently used in clinical settings, the potential of neurophysiological features to become brain oscillatory brain biomarkers, and their use in fut [...]

1311 7821

Open Access Original Research

Overall Reaction Rate Study of Thermal Methane Cracking in Non-Isothermal Conditions

Received: 10 April 2023;  Published: 13 September 2023;  doi: 10.21926/jept.2303028

Abstract

The thermal cracking of methane (TMC) is a significant reaction occurring above 850°C, which proceeds in two stages: non-isothermally and isothermally. However, most existing studies have focused on obtaining reaction rates under isothermal conditions [1], limiting their applicability to practical industrial reactor conditions. This novel research aims to determine the overall thermal decomposition rate of methane to hydrogen and carbon in adiabatic conditions, covering the range of unstable industrial reactor temp [...]

1720 7815

Open Access Case Report

Prolonged and Resistant Cutaneous Infection in Newly Transplanted Renal Patient

Received: 18 October 2018;  Published: 07 March 2019;  doi: 10.21926/obm.transplant.1901057

Abstract

Mucormycosis is an angioinvasive and potentially fatal fungal infection caused by ubiquitous filamentous fungi. Cutaneous mucormycosis is an emerging infection and potentially lethal. Our aim was to review the literature on cutaneous mucormycosis. We present a case of a renal transplant patient with a surgical wound infection 20 days after kidney transplant. This case is an example on how early diagnosis is crucial and, since culture is less sensitive, microscopic evaluation of the characteristic broad hyphae is th [...]

1256 7812

Open Access Original Research

Fabrication and Catalytic Property of an Ordered Terpyridine Pd(II)/Ni(II) Catalytic Monolayer for Suzuki Coupling Reactions

Received: 21 September 2022;  Published: 02 December 2022;  doi: 10.21926/cr.2204042

Abstract

Fabrication, arrangement, and controllable composition of ordered organometallic films are critical for designing a highly active catalyst and investigating the catalytic mechanism. In this paper, an organometallic terpyridine Pd(II)/Ni(II) monolayer linked on the silicon substrate surface (denoted as Si-Tpy-Pd1/Ni1) was prepared and characterized using water contact angle, ultraviolet spectra, X-ray diffraction, scanning electron microscopy, and X-ray photoelectron microscopy. Si-Tpy-Pd1/Ni1 exhibited high catalyt [...]

1106 7807

Open Access Original Research

Coronavirus Disease 2019 (COVID-19) Pandemic’s Effect on Child and Adolescent Mental Health: Analysis of Pediatric Intensive Care Unit and Consultation-Liaison Psychiatry Service

Received: 03 October 2022;  Published: 02 March 2023;  doi: 10.21926/obm.neurobiol.2301159

Abstract

The Coronavirus Disease (COVID-19) pandemic has contributed to a co-occurring psychiatric epidemic. Children and adolescents have been particularly impacted, with disruptions in continuity of learning and healthcare. Psychological stressors such as fear of infection, boredom, decreased socialization, supply shortages, and incomplete information have contributed to low mood, irritability, insomnia, and emotional exhaustion. Our study contributes to this research by quantifying the devastating psychiatric toll that t [...]

1138 7806

Open Access Editorial

Prospects of Platelet-Rich Plasma in Regenerative Medicine

Received: 25 May 2023;  Published: 02 June 2023;  doi: 10.21926/obm.transplant.2302187

Abstract

Platelet-rich plasma (PRP) is a promising tool in regenerative medicine because it stimulates tissue repair and regeneration. PRP contains a high concentration of platelets, growth factors, and cytokines involved in the healing process. This editorial paper aims to give an overview of PRP in regenerative medicine and its potential applications in various medical fields such as orthopedics, dentistry, dermatology, and wound healing. PRP can be integrated with other regenerative therapies, such as stem cell and gene [...]

1262 7806

Open Access Research Article

Saving is Losing: Pumping Cost vs. GHG Emissions in Water Distribution Systems

Received: 26 May 2023;  Published: 21 November 2023;  doi: 10.21926/jept.2304037

Abstract

Global climate change has necessitated the reduction of GHG emissions. Water distribution system (WDS) pumping adds to these emissions and, therefore, should be reduced. Under electricity hourly cost tariffs, utilities are incentivized to pump during the nighttime hours. This can have a deleterious effect, however, on GHG emissions. To quantify this effect, a modeling study of twelve real WDSs was performed with an electricity tariff. The systems all had the typical tank-level-based pump controls but also time-base [...]

1554 7798

Open Access Original Research

Research and Application of Modified ZSM-5 for the Process of Alkylation of Oil Distillate Fractions

Received: 20 April 2023;  Published: 10 August 2023;  doi: 10.21926/cr.2303021

Abstract

In the oil distillate fraction alkylation process, a modified Zr zeolite ZSM-5 was obtained and studied. The modification was executed using a method that impregnated ZSM-5 with a 5% solution of ZrOCl2∙6H2O. X-ray diffraction studies were conducted on zeolite ZSM-5, zirconyl chloride modifier ZrOCl2∙6H2O, and modified zeolite ZSM-5-ZrO2, which was calcined at temperatures of 200, 400, and 550°C. The results revealed that the phase composition of modified ZSM-5-ZrO2 zeolite samples varied depending on the calcinatio [...]

1191 7795

Open Access Original Research

Energy Self-Sufficiency in Rural Areas; Case Study: North Euboea, Greece

Received: 28 August 2024;  Published: 05 December 2024;  doi: 10.21926/aeer.2404025

Abstract

The modern globalized civilization is sustained by interactions, trade, the transportation of goods, and energy. Energy self-sufficiency is crucial in rural and disaster-prone areas like North Euboea because dependence on external energy supplies can leave regions vulnerable to supply chain disruptions, price volatility, and geopolitical risks. In such isolated regions, energy independence ensures resilience in natural disasters and economic instability. The alternative to self-sufficiency often involves reliance o [...]

985 7793

Open Access Review

Nanomaterials with Plant or Animal Origin for Greener Biodelivery and Biosensor Applications: A Review

Received: 26 October 2022;  Published: 12 June 2023;  doi: 10.21926/rpm.2302023

Abstract

Nanomaterials are now used in almost every field of science; as conductors and electrodes in electronics, as nanodelivery systems in health screenings and drug delivery, as nanofibrils in filtering and textile industry, as nanoparticles in biosensor fabrication for toxin and pathogen detection, and in packaging materials in the food industry. Synthetic materials and plastics accumulate in the environment causing increasing health concerns for their use in food and pharmaceutical products. Therefore, researchers now [...]

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Open Access Original Research

Hydrochemical Characteristics of Groundwater in the Mutoshi Deposit Environment, Kolwezi (Lualaba, DR Congo)

Received: 19 September 2024;  Published: 16 April 2025;  doi: 10.21926/aeer.2502019

Abstract

This study examines the hydrochemical characteristics of groundwater in the Mutoshi mining environment in Kolwezi, Democratic Republic of Congo, addressing gaps in understanding the impact of mining on water quality. Despite the DRC's vast water resources, only 26% of the urban population has access to safe drinking water, with the Mutoshi aquifer, providing over a quarter of Kolwezi's drinking water, facing deterioration due to underlying copper and cobalt-rich geological formations. Groundwater and geological sam [...]

1156 7791

Open Access Editorial

Mitochondria, Brain, Heart and Body

by Ya Wen
Received: 28 November 2017;  Published: 05 December 2017;  doi: 10.21926/obm.neurobiol.1704007

Abstract

More and more studies revealed links amongst neurological disorders, heart diseases and cancers. For example, people with subclinical cardiovascular diseases are at higher risk for Alzheimer's disease, Parkinson’s disease is associated with varied risk of cancer, Autism Spectrum Disorders and cancer have overlapping genes and molecular pathways, heart disease and cancer share common risk factors, etc. It is intriguing how are these conditions that appear to be completely different linked together.

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Open Access Review

Human Interference with the Earth Has Abolished the Next Ice Age but Overdosing with Carbon Dioxide Emissions Could Have Catastrophic Consequences

Received: 29 November 2021;  Published: 28 November 2022;  doi: 10.21926/aeer.2204046

Abstract

Around 1600 AD the carbon dioxide content of the earth’s atmosphere started to rise, even whilst according to the Milankovitch [1] astronomical theory of climate variation it was due to fall. On the natural earth the carbon dioxide count of the atmosphere is a delayed response and an enhancing feedback on the basic cause of the Milankovitch astronomical cycle, the intensity of the June sunshine. If the Milankovitch cycle had continued its natural course, the medevial cold period known as the little ice age. Human i [...]

1159 7787

Open Access Interview

An Interview with Dr. Yuri Shavrukov

Received: 09 January 2023;  Published: 10 January 2023;  doi: 10.21926/obm.genet.2301176

Abstract

An Interview with Dr. Yuri Shavrukov

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