by Lisa Vogelgesang  , Damien Moore  and Paul D. Loprinzi

Received: 12 April 2020;  Published: 15 April 2020;  doi: 10.21926/obm.icm.2002020

by Alicia M Teagarden  , Emma M Tillman  and Courtney M Rowan

Received: 24 April 2018;  Published: 29 October 2018;  doi: 10.21926/obm.transplant.1804022

Background: Hematopoietic cell transplant (HCT) patients are a high-risk population for poor nutrition and decreased survival. There is little data on how nutrition in pediatric HCT patients affects need for critical care interventions and outcomes. Methods: We hypothesized that patients who did not meet goal nutrition by 72 hours post-admission to the pediatric intensive care unit (PICU) had increased in-hospital mortality and increased need for critical care interventions. We performed a retrospective cohort stud [...]

by Lindsay E. Turgeon-Brown

Received: 19 November 2024;  Published: 07 April 2025;  doi: 10.21926/obm.icm.2502017

Teachers face at-work risk factors including compassion fatigue, burnout, dealing with violence, and a teacher shortage. A review of the literature shows that self-care can have positive benefits that mitigate and help to buffer these at-work risk factors This study examines teachers’ stories of self-care. The data suggests that self-care is a positive practice for teachers professionally and personally.

by Faraz Estelaji  , Alireza Naseri  and Rahim Zahedi

Received: 08 October 2022;  Published: 26 December 2022;  doi: 10.21926/aeer.2204057

Crisis management assessment and planning include many components. One of the essential elements is the review and analysis of the structure of the existing situation and the performance of Vital services in the face of critical cases. During the occurrence of natural disasters, the issue of crisis management is crucial in order to reduce the damages caused by the crisis. One thing that reduces the damages is the correct and timely access of critical relief centers such as fire departments, emergency, police force, [...]

by Upasana Ramphal  , Derek Tshiabuila  , Yajna Ramphal  , Jennifer Giandhari  , Carel van Heerden  , Cheryl Baxter  , Stephanie van Wyk  , Sureshnee Pillay  , Oluwakemi Laguda-Akingba  , Eduan Wilkinson  , Richard Lessells  and Tulio de Oliveira

Received: 01 March 2024;  Published: 30 May 2024;  doi: 10.21926/obm.genet.2402239

During the SARS-CoV-2 pandemic, next-generation sequencing (NGS) technologies like the Ion Torrent S5 and Illumina MiSeq, alongside advanced software, improved genomic surveillance in South Africa. This study analysed anonymized samples from the Eastern Cape using Genome Detective and NextClade, showing Ion Torrent S5 and Illumina MiSeq success rates of 96% and 94%, respectively. The study focused on genomic coverage (above 80%) and mutation detection (below 100), with the Ion Torrent S5 achieving 99% coverage comp [...]

by OBM Integrative and Complementary Medicine Editorial Office

Received: 25 January 2022;  Published: 28 January 2022;  doi: 10.21926/obm.icm.2201004

Interview with Dr. Paul J. Arciero. Precision lifestyle medicine and implementation science are the emerging frontiers of research in his field. He is an applied physiology and nutrition scientist, specializing in evidence-based scientific research on integrative and complementary lifestyle strategies to optimize health, wellness, and performance in individuals and organizations of all ages, fitness and health status. Specifically, his PRISE® Life protocol emphasizes a qualitative approach to nutrition, fitness, an [...]

by Zachary Zeigler  , Jacob Lawrence  , Alexa Jamison  and Pete Salzano

Received: 02 August 2021;  Published: 02 September 2021;  doi: 10.21926/obm.icm.2103027

Statistical modeling indicated that COVID-19 would have afflicted more than 60% of the US population. Social distancing, self-quarantine, and widespread shutdowns were imposed. The push to stay at home and the decreased availability of exercise facilities have potentially reduced physical activity (PA). The purpose of this observational, correlational study was to determine if there is a relationship between PA level and symptoms of COVID-19. Subjects were asked to complete a single Survey Monkey questionnaire. The [...]

by Richard A. Manfready  , Jack Husney  , Swan Thung  and Ilan S. Weisberg

Received: 04 March 2020;  Published: 25 September 2020;  doi: 10.21926/obm.hg.2003051

Patients receiving immunosuppressive therapy for inflammatory bowel disease may be susceptible to non-cirrhotic portal hypertension, now referred to as porto-sinusoidal vascular disease. Here we describe a patient treated with long-term azathioprine for Crohn’s disease who developed porto-sinusoidal vascular disease with obliterative portal venopathy without nodular regenerative hyperplasia on histology. Specific signs of portal hypertension were present, including porto-systemic collaterals on imaging. Histopathol [...]

by Vincenzo Prisco  , Bernadette Donnarumma  and Lorenzo Prisco

Received: 27 March 2020;  Published: 03 December 2020;  doi: 10.21926/obm.neurobiol.2004079

Anecdotal evidence suggests the possible association of psychiatric disorders with Mӧbius sequence, although the evidence is not conclusive. Intermittent presentation of auto-aggressive outbursts, in particular, could be related to Mӧbius sequence, different from the common psychotic symptoms. The present report describes the clinical case of a young man with Mӧbius syndrome who exhibited a complex representation of severe mental retardation and concomitant psychiatric disorders. Extremely rare psychiatric disorder [...]

by Ala Masri  and Marwan Ghanem

Received: 28 September 2022;  Published: 19 December 2022;  doi: 10.21926/aeer.2204053

The main research objective is to highlight the potentiality of artificial groundwater recharge in Al-Qilt catchment- Jericho - Palestine regarding the water shortage in the groundwater-supplied areas. Artificial recharge can be a possible option in increasing the storability of the underground aquifer, which will add values to the Palestinian strategy to optimize the total accessibility of groundwater resources. The increase of water demands and the scarcity of water resources in the Jordan Rift areas are putting [...]

by Giuseppe Cocco

Received: 05 September 2020;  Published: 10 September 2020;  doi: 10.21926/obm.geriatr.2003132

Covid-19 pandemic has been infecting a substantial portion of the world population, thereby revealing quality deficits in health care in the majority of the countries around the globe. Severe illness and mortality from Covid-19 infection are present predominantly in minorities; especially they are more frequent in geriatric patients. Unfortunately, our knowledge is limited about what accounts for the variability in immune response from one person to another. This question is far from being merely academic, and find [...]

by Robert T. Rubin

Received: 14 March 2019;  Published: 18 April 2019;  doi: 10.21926/obm.icm.1902025

There are several definitions of sympathy, empathy, and compassion on the internet. I have chosen the above definitions to emphasize their salient differences, for the following reason: In medical school, in the early 1960s, we were taught not to sympathize with patients, but to empathize: By empathizing, one can retain some professional objectivity toward the patient, in order to be of some help. To sympathize, on the other hand, was to immerse oneself in the patient’s suffering and lose one’s professional per [...]

by Syed Nazeer Mahmood  and Amit K. Mahajan

Received: 12 September 2023;  Published: 27 March 2024;  doi: 10.21926/obm.transplant.2401209

Lung transplantation in patients with end stage lung disease can improve survival and quality of life. Airway complication incidence varies between 2-33%, but the true incidence is difficult to determine due to a lack of validated classification systems. There are many risk factors for post lung transplant airway complications, the most common being anastomotic ischemia, pulmonary infections, surgical technique and allograph dysfunction. Common complications include formation of granulation tissue, anastomotic sten [...]

by Beth Levant  , Emma Nguyen  , Jennifer A. Villwock  and Ann M. Manzardo

Received: 27 February 2023;  Published: 10 April 2023;  doi: 10.21926/obm.icm.2302018

Impostorism is prevalent in medical students and negatively impacts wellness, contributing to stress and burnout. Perceived competence is noted as one attribute underlying impostorism. A curricular change that resulted in improved United States Medical Licensing Examination (USMLE) Step 1 scores and student self-perceptions of preparedness for clinical training was used as a natural experiment to assess the effects higher competence/preparedness, based on an objective indicator and self-perceptions, on impostorism, [...]

by Daniel Hughes  , Alex Gordon-Weeks  and Michael A Silva

Received: 30 April 2019;  Published: 19 July 2019;  doi: 10.21926/obm.hg.1903028

(1) Background: Hereditary Pancreatitis is a rare cause of acute pancreatitis. These patients usually present at a young age with recurrent episodes of acute pancreatitis that usually progresses to chronic pancreatitis with associated endocrine and exocrine failure. Hereditary pancreatitis also carries an increased lifetime risk of pancreatic adenocarcinoma. These high risk patients need early intervention where appropriate by specialist multidisciplinary teams and tailored long term management. (2) Methods [...]

by Katsuhisa Omagari  , Risa Kumamoto  , Yuko Koyama  , Masako Suzuta  , Asami Taniguchu  , Ayumi Fukuda  , Momoe Iwami  , Kazunori Koba  , Asako Kawaguchi  and Kazunori Otsuka

Received: 10 April 2020;  Published: 19 May 2020;  doi: 10.21926/obm.hg.2002048

Chronic constipation and irritable bowel syndrome (IBS) are two of the most common functional gastrointestinal disorders, both of which negatively affect the quality of life of the patients. Since people may have co-existing symptoms of multiple disorders, chronic constipation and IBS with predominant constipation cannot be clearly distinguished. In this cross-sectional study, data were obtained from self-administered questionnaires to assess the prevalence of chronic constipation and IBS, and their overlap, among [...]

by Michel Z. Fidelis  , Elaine Trojan de Paula  , Eduardo Abreu  , Maria E.K. Fuziki  , Onelia A. A. dos Santos  , Rodrigo Brackmann  and Giane G. Lenzi

Received: 18 September 2023;  Published: 22 September 2023;  doi: 10.21926/cr.2303023

Due to its similar characteristics to titanium, niobium has become an attractive alternative in photocatalytic processes. Research indicates that titania has an optimal percentage of phases resulting in a commercial catalyst, P25, that contains more than 70% anatase with a minor amount of rutile and a small amount of amorphous phase. On the other hand, for Nb2O5, percentage optimization was little explored in the literature, which consists of studying the phases obtained via heat treatment individually and in diffe [...]

by Danae M. Maes  , August Finke  , Chuck R. Smallwood  , J. Bryce Ricken  , Jerilyn A. Timlin  and Anne M. Ruffing

Received: 11 April 2022;  Published: 14 June 2022;  doi: 10.21926/aeer.2202025

Expanded industrial globalization has resulted in the release of high concentrations of heavy metals into environmental water sources and soils. Phytoremediation may help to remove these heavy metals from contaminated soils. Tall fescue (Festuca arundinacea Shreb.) exhibits phytoremediation potential due to its endurance and high stress tolerances. Here, we report photochemical and structural responses in tall fescue to acute and chronic doses of heavy metals, copper (Cu) and hexavalent chromium (Cr(VI)). Visual si [...]

by Livinus Emebiri

Received: 18 August 2023;  Published: 24 November 2023;  doi: 10.21926/rpn.2304023

Wheat (Triticum aestivum L.) is pivotal to global food security, with its energy-rich grains that are also the major vegetable protein source in human diets. Decades of primary emphasis on grain yield improvement have delivered increased gains worldwide, but the grain protein content has declined. Since amino acids are biosynthetic precursors of proteins, this research hypothesized that their contents in the wholegrain flour have also been impacted by past wheat breeding. To test this, the free amino acid content o [...]

by Daniel Thiel

Received: 21 February 2023;  Published: 15 May 2023;  doi: 10.21926/aeer.2302031

This research aims to model and compare two strategies for locating new hydrogen refueling stations (HRS) in a context of high uncertainty on H2 demand and on the spatial distribution of demand points. The first strategy S1 represented by an agent-based model integrating a particle swarm optimization metaheuristic consists of finding the best HRS locations by adapting to the real evolution of the demand. A second strategy S2 consists in solving a classical capacitated p-median problem based on H2 consumption foreca [...]

by Abhay Vashishth  , Mohd Shuaib  , Tanya Bansal  and Shashank Kumar

Received: 03 September 2022;  Published: 21 June 2023;  doi: 10.21926/obm.genet.2302183

Lung cancer is a leading cause of death among all the cancer worldwide and it has the highest occurrence and mortality rates. Mycobacterium tuberculosis (MTB) induced tuberculosis has been known as one of the risk factors for lung carcinogenesis. The exact mechanism of MTB is understood to date. Several research and epidemiological studies about the link between tuberculosis and lung cancer exist. It has been proposed that tuberculosis causes chronic inflammation, which increases the risk of lung cancer by creating [...]

by Eugene Adamovich  , Eugenia Buryanskaya  , Anthon Elfimov  , Irina Maklakova  , Oleg Gradov  , Margaret Gradova  and Theodor Orehov

Received: 27 December 2022;  Published: 29 May 2023;  doi: 10.21926/rpm.2302022

In this paper, starting with an introductory review of the applications of liquid crystals and polymer-dispersed liquid crystal systems in (bio)sensors and microfluidics, the possibilities of visualizing self-organization products of liquid crystalline media or field-induced instabilities of liquid crystalline systems are considered. In particular illustrated cases, it is proposed to use FemtoScan software-containing metrological complexes to visualize instabilities in liquid crystalline systems and products of sel [...]

by Giacinto Libertini

Received: 22 July 2022;  Published: 14 October 2022;  doi: 10.21926/obm.geriatr.2204208

The interpretation of aging as an adaptive and programmed phenomenon implies the existence of specific genetically determined and regulated aging-causing mechanisms. This interpretation is in contrast to the explanation of aging as the gradual accumulation of the effects of harmful factors that are only partially countered by natural selection. The subtelomere–telomere theory of aging offers what is required by the interpretation of aging as a programmed phenomenon. The experimentally documented mechanisms that are [...]

by Joseph S. D'Arrigo

Received: 08 December 2021;  Published: 29 March 2022;  doi: 10.21926/obm.neurobiol.2201117

Cerebrovascular atherosclerosis, and several other cardiovascular (or "inflamm-aging" type) diseases, are more frequent and advanced in subjects with Alzheimer's disease compared with normal aging. In addition, the observed pathogenic link to dementia (and its associated cerebral microvascular damage) is readily explained by alterations of arterial elasticity. A therapeutic strategy to delay dementia could be based upon localized drug delivery, using lipid nanocarriers (i.e., biobased nanoemulsion technology), targ [...]

by Vincenza Rita Lo Vasco

Received: 27 January 2023;  Published: 05 May 2023;  doi: 10.21926/obm.geriatr.2302234

Illnesses following the degeneration of the nervous system can occur due to aging or genetic mutations and represent a clinical concern. In neurodegenerative diseases, loss of neuronal structure and functions mainly causes cognitive impairment, representing an increasing social burden. In neurodegenerative diseases, the progressive loss of vulnerable populations of neurons in specific regions of the central nervous system was traced to different pathological events, such as misfolded proteins’ accumulation, abnorma [...]

by Rotu Arientare Rume  , Oyovwi Mega Obukohwo  , Ohwin Peggy Ejiro  and Oyelere Abosede Oreoluwa

Received: 04 December 2023;  Published: 27 February 2024;  doi: 10.21926/obm.icm.2401015

Regular physical activity has been proven to improve metabolism, slow aging, and decrease the likelihood of various health conditions such as obesity, type 2 diabetes, and cardiovascular disorders. Hence, dancing was evaluated for its effects on cardiovascular, liver enzymes, and biochemical markers among healthy adults. Forty (40) healthy adults (20-40 years old) were chosen for the study, with an average age calculated. Those with certain health conditions or habits were not allowed to participate. Twenty (20) me [...]

by Fernando Cabo  and Isaac Aguaristi

Received: 01 April 2020;  Published: 02 April 2020;  doi: 10.21926/obm.icm.2002018

by Hana Alharbi  and Miao He

Received: 16 April 2023;  Published: 31 August 2023;  doi: 10.21926/obm.genet.2303191

The aim of newborn screening (NBS) program is to detect and manage treatable conditions in the early stages prior to the occurrence of long-term and irreversible sequalae. Phenylketonuria was the first screened disorder, but panels rapidly expanded after the introduction of tandem mass spectrometry technology into the program. Significant differences in the diseases screened by NBS were noted between programs in United States. Therefore, the recommended uniform screening panel was developed in 2006 to include a lis [...]

by Rezarta Lalo  , Fatjona Kamberi  and Vjollca Ndreu

Received: 06 January 2023;  Published: 15 May 2023;  doi: 10.21926/obm.neurobiol.2302169

Pregnancy and postpartum periods are known as sensitive periods in women’s life and COVID-19 pandemic seems to be worsening their mental health with major impacts on exclusive breastfeeding duration. Therefore, the present study aims to fill the gap in the literature by assessing the links between postpartum anxiety and depression symptoms and breastfeeding duration as well as the associated factors during the COVID-19 pandemic. A longitudinal prospective observational study was conducted between November and [...]

by Nuchanart Suntornnont  , Ammaraluk Kovavisarach  and Rachaneekorn Tammachote

Received: 05 July 2024;  Published: 06 January 2025;  doi: 10.21926/obm.genet.2501279

Keratinocytes are particularly vulnerable to oxidative stress due to their function as the primary natural protective barrier exposed to chemicals, rays, and pollution to stimulate the formation of free radicals in the body. Two factors of interest correlate with cellular senescence under oxidative stress. These include regulating antioxidant synthesis, which maintains free-radical homeostasis through the Nrf2 gene, and the prevention of telomere shortening, which involves the collaboration of human telomerase gene [...]

by Anita H Kelleher  and Angelos K Sikalidis

Received: 09 November 2020;  Published: 05 February 2021;  doi: 10.21926/obm.hg.2101056

The Mediterranean diet (MD) is considered one of the healthiest dietary patterns due to its rich provision of phytochemicals, antioxidants, vitamins, fiber, polyunsaturated, omega-3, and short-chain fatty acids through a variety of foods. The supply of such nutrients and bioactive components can support gut health and reduce systemic inflammation, with accumulating evidence from several human studies demonstrating the utility of the Mediterranean diet in the prevention of chronic and metabolic diseases. Further stu [...]

by Giuseppe Cocco

Received: 20 March 2020;  Published: 01 April 2020;  doi: 10.21926/obm.geriatr.2002112

by Sai Batchu  , Michael J. Diaz  , Lauren Ladehoff  and Brandon Lucke-Wold

Received: 27 September 2022;  Published: 03 February 2023;  doi: 10.21926/obm.neurobiol.2301153

Genes encoding for proteins associated with the plasma membrane, referred to as the membranome, have long been recognized to play an important role in the development and maintenance of glioblastoma multiforme (GBM). GBM cell lines are commonly used to mimic tumors for in vitro experiments, but the extent to which they resemble GBM tumors in relation to the membranome is unclear. The present study explores the resemblance of GBM cell lines to primary tumors regarding membranome expression. Gene expression data was [...]

by Mohammed Naveed

Received: 22 December 2022;  Published: 12 April 2023;  doi: 10.21926/rpm.2302015

Composite materials with aluminum as matrix material have a wider amplitude of large-scale applications in engineering. Some salient features of aluminum matrix composites are, low density, low thermal coefficient of performance and low weight and high strength. Among the various series of aluminum alloy, Al6061 have been widely used by researchers due to its outstanding properties particularly as they are heat treatable. Aluminum 6061 alloys have been reinforced with various particulate reinforcements such as sili [...]

by Marco Minella  , Khan M.G. Mostofa  , Cong-qiang Liu  and Davide Vione

Received: 05 September 2019;  Published: 21 January 2020;  doi: 10.21926/obm.acr.2001004

Superoxide, produced photochemically as well as microbially, is an important reactant present in seawater and a major source of hydrogen peroxide. Superoxide decay may occur through catalyzed or uncatalyzed dismutation forming H2O2 and O2, through oxidation to O2, or through reduction into H2O2. Under definite circumstances, the redox processes that are different from dismutation could produce or consume H+, thereby altering the pH of seawater. In order to alter the pH, these processes have to involve, together wit [...]

by Katarina Tomulic Brusich

Received: 30 August 2022;  Published: 15 November 2022;  doi: 10.21926/obm.transplant.2204169

Transplantation is a widely accepted and successful life-saving treatment for hundreds of thousands of patients. However, transplant medicine still faces a number of obstacles. One of the most significant is the large disparity between the number of donors and recipients and the growing need for re-transplantation. In the last two decades, the improvement and organization of the national transplantation program in Croatia have resulted in a steadily increasing donor rate and therefore the transplantation numbers. A [...]

by Andrey Koptyug  , Yurij Sukhovei  , Elena Kostolomova  , Irina Unger  and Vladimir A. Kozlov

Received: 14 April 2023;  Published: 22 December 2023;  doi: 10.21926/obm.geriatr.2304263

Understanding processes related to human aging and rejuvenation relies on experimental data and advanced models operating at different levels. There are several existing conceptual and specific modeling approaches. However, one of the existing tasks is compiling generic models linking properties at cell and cell-element levels to properties at systemic levels - tissue, organ, and whole body. One of the critical issues in the relevant models is the enormity of interacting components at the cell and sub-cell levels n [...]

by Hossein Hosseinkhani

Received: 26 August 2024;  Published: 12 December 2024;  doi: 10.21926/rpm.2404027

Viral and non-viral vectors for nucleic acids (DNA/RNA) therapeutics are important in development of pharmaceutical industries. Although viral vectors have shown significant impact in transfection of DNA/RNA, but numerus studies have shown that non-viral vectors are also effective for the safe and targeted delivery of DNA/RNA to exact location in the body with high percentage of efficacy, safety, and low-immunogenicity. It is also important to protect the nucleic acids from degradation and large-scale production ca [...]

by Ousman Bajinka  , Mamtuti Panneh  , Sang Mendy  , Amadou Barrow  , Haddy Bah  , Lamarana Jallow  , Jarry Jallow  , Kaddy Drammeh  , Kaddijatou Kah  , Oulimatou Lateef  , Mariama A Bah  , Isatou K Sillah  , Fatoumata Bah  , Nyima Ceesay  , Mariama Jaiteh  and Yurong Tan

Received: 31 August 2024;  Published: 08 April 2025;  doi: 10.21926/rpn.2502006

The adverse effects of maternal passive smoking during pregnancy on offspring health remain understudied in sub-Saharan Africa, particularly in The Gambia, where smoke-free regulations are limited. To determine the prevalence of maternal passive smoking (MPS) during pregnancy and investigate its associations with adverse pregnancy outcomes and offspring health complications in The Gambia. A cross-sectional study was conducted in February 2023 among 401 mothers with children under 5 years in urban and rural regions [...]

by Miles Nevills  , Spencer Jones  and Ethan Languri

Received: 31 October 2024;  Published: 24 June 2025;  doi: 10.21926/aeer.2502024

Across the industrial sector, compressed air is utilized as an easy-to-use and readily accessible tool in a variety of applications. This tool is commonly misunderstood as being more efficient than it is in reality. Air compression is energy intensive and thus both economically and environmentally costly. Compressed air typically only achieves around ~15% efficiency if judged by the energy delivered from the air, meaning approximately 5-6 kWh are wasted for every 1 kWh of useful work performed by compressed air. Du [...]

by Marek Łożyński  , Iwona Mądrzak-Litwa  and Aleksandra Borowiak-Resterna

Received: 29 June 2020;  Published: 27 August 2020;  doi: 10.21926/acr.2003007

1-Decylbenzimidazole (dbim) copper(II) complexes formed during solvent extraction were thoroughly studied, and their structures were predicted. Density functional theory (DFT) calculations of their structures and Time-dependent DFT (TD-DFT) calculations of their spectra indicated that 1-decylbenzimidazole forms both mono- and binuclear complexes with copper(II), with coordination numbers of 4 or 5. At the molar ratio of [Cu(II)]aq/[dbim]org ≥ 1 and at [Cl-]aq ≥ 0.9 mol dm-3 in the extraction media, a binuclear 1:1 [...]

by Mahintaj Dara  , Zahra Karimi  , Mehdi Dianatpour  and Hadi Aligholi

Received: 02 June 2024;  Published: 30 September 2024;  doi: 10.21926/obm.neurobiol.2403246

Zebrafish (Danio rerio) is a vertebrate with unique characteristics, making it an excellent biomedical research animal model. One research area involves investigating changes in gene expression during neurodegenerative processes, aging-related changes, and behavioral studies in zebrafish. To achieve this, high-quality and quantity RNA must be extracted from zebrafish. This study aims to develop an optimized RNA extraction method from zebrafish larvae brains. After rearing and maintaining the zebrafish in suitable c [...]

by Axel Ferreira  , Filipa Guimarães  and Paulo Simões Coelho

Received: 29 September 2020;  Published: 24 December 2020;  doi: 10.21926/obm.geriatr.2004145

We present a case of a 74-year-old woman with deep intracerebral hemorrhage (ICH), probable cerebral amyloid angiopathy (CAA), and probable antiphospholipid syndrome (APS). Due to the high hemorrhagic risk, it was decided not to use anticoagulants. In a period of three months, she had two separate cerebral ischemic events and died of stroke-related complications. The use of oral anticoagulation (OAC) in this patient is neither supported nor contra-indicated by current literature, even though past medical history su [...]

by Gopi Battineni  , Mohammad Amran Hossain  , Nalini Chintalapudi  , Giulio Nittari  , Ciro Ruocco  , Enea Traini  and Francesco Amenta

Received: 29 June 2022;  Published: 03 January 2023;  doi: 10.21926/obm.geriatr.2301220

The increasing incidence of adult-onset dementia disorders and primarily Alzheimer’s disease (AD) among the aging population around the world is increasing the social and economic burden on society and healthcare systems. This paper presents three neural networking algorithms: MobileNet, Artificial Neural Networks (ANN), and DenseNet for AD classification based on MRI imaging data. The results of each model were compared in terms of performance metrics such as accuracy, true positive rate, and receiver operating cu [...]

by Buti Obaid Saeed Alfalahi  , Imane Lamdjad  , Mustafa Alnujaifi  , Noaman Atallah Alheety  and Abdul Qayyum

Received: 05 February 2024;  Published: 12 June 2024;  doi: 10.21926/obm.genet.2402242

Understanding the impact of melatonin (N-acetyl-5-methoxytryptamine) on plant gene expression is crucial for unlocking its full potential as a tool for crop improvement and stress tolerance. Melatonin has emerged to have several influences on the transcriptional activity of numerous genes, helping to orchestrate plant responses to environmental cues. Furthermore, it has been shown that melatonin signaling pathways control downstream gene expression to ensure proper plant growth and development. Therefore, clearing [...]

by Elham Amjad  and Babak Sokouti

Received: 21 February 2025;  Published: 09 June 2025;  doi: 10.21926/obm.transplant.2502251

Graft rejection, early allograft dysfunction (EAD), and poor diagnostic accuracy are some of the challenges that still need to be addressed, even though liver transplantation (LT) has the potential to help patients with end-stage liver disease (ESLD) significantly. Traditional procedures, such as liver biopsies and liver function tests (LFTs), often fail to identify abnormalities early and with accuracy. Genomic RNA sequencing (RNA-Seq) has recently emerged as a powerful approach for identifying molecular markers o [...]

by Despina Vamvuka  , Katerina Esser  , Dimitrios Marinakis  and George Kalantzakis

Received: 02 November 2022;  Published: 11 January 2023;  doi: 10.21926/aeer.2301005

This work aimed at evaluating all products from the low-temperature pyrolysis (350°C) of some industrial wastes, cotton stems and seeds (CSS), grape husks and curls (GRH), undigested sewage sludge (USS) and their blends in a fixed bed system and suggesting their possible applications. Solid and liquid products, biochars, and bio-oils were analyzed using various techniques by physicochemical, mineralogical, and chemical analyses. Gases were qualitatively and quantitatively analyzed using a thermogravimetric-mass [...]

by Bernard R. Baum  and Douglas A. Johnson

Received: 07 January 2022;  Published: 24 April 2022;  doi: 10.21926/obm.genet.2202152

We have investigated the utility of the 5S nrDNA, a conserved, multicopy gene family organized into tandem repeats as a tool for genetic analyses in a wide variety of genera. Previous work in the Triticeae (Poaceae) demonstrated that the prior identification of unit classes based upon the 5S nrDNA NTS, greatly facilitates analysis. We investigated the potential of defining unit classes in other plant genera and several animal genera as a step towards future phylogenetic analyses. Our results demonstrate that in in [...]

by Gerhard Litscher

Received: 05 January 2025;  Published: 07 January 2025;  doi: 10.21926/obm.icm.2501003

Acupuncture, an ancient practice in traditional Chinese medicine, is founded on understanding of human physiology and the dynamics of energy flow (Qi). The emergence of artificial intelligence (AI) in modern medicine presents opportunities to integrate advanced technologies into acupuncture, enhancing diagnostic precision and empirical validation. AI tools can analyze complex datasets, model energy flow dynamics, and provide evidence-based insights, potentially bridging traditional methodologies with scientific par [...]

by Giacomo Farì  , Enrica Chiaia Noya  , Laura Dell'Anna  , Vincenzo Ricci  , Francesco Quarta  , Laura Masiero  , Andrea Bernetti  , Marisa Megna  and Maurizio Ranieri

Received: 16 January 2024;  Published: 25 June 2024;  doi: 10.21926/obm.neurobiol.2402227

Wheelchair basketball (WB) is a health and inclusion opportunity for people with disabilities. In the scientific literature, no evidence defines WB as a symmetrical or asymmetrical sport; however, it would be helpful to deepen this aspect because it could improve the quality of training programs and consequently speed up WB performance. In WB, the biomechanical role of the shoulders is crucial. Therefore, the symmetry index and the activation of the bilateral supraspinatus and biceps brachii muscles were investigat [...]