by Úrsula Oswald-Spring

Received: 06 November 2022;  Published: 06 June 2023;  doi: 10.21926/aeer.2302035

The present article studies the policy, numbers, and costs of disaster risk management (DRM) in Mexico, a country highly exposed to climate change, due to two oceans warming up. The PEISOR methodology facilitates interrelating complex interactions and pressures between the natural and the societal system (P), where dangerous effects (E) occur in extreme events, such as floods, landslides, and drought. The impacts (I) of global warming, the pressure of historical poverty, and vulnerable regions were affected by the [...]

by Azra Shafi  and Qayyum Husain

Received: 06 August 2022;  Published: 17 November 2022;  doi: 10.21926/cr.2204040

Interpreting the relationship between the activity and structure of β-galactosidase is necessary to perceive the impact of the enzyme’s conformation on its catalysis. The current study thoroughly explains the effects of additives such as ethylenediaminetetraacetic acid (EDTA), sodium dodecyl sulfate (SDS), dithiothreitol (DTT), and urea on β-galactosidase activity and structure. β-Galactosidase activity was determined at various ionic strengths and temperatures as a function of time. Structural [...]

by Virginie Vignard  and Delphine Fradin

Received: 13 March 2018;  Published: 15 May 2018;  doi: 10.21926/obm.genet.1802020

Melanoma is a highly aggressive skin cancer with high incidence worldwide. There is growing evidence that aberrantly expressed non-coding RNAs (ncRNAs) play a role in the development, progression and dissemination of melanoma tumor cells. Among the many types of ncRNAs described in this review, the functions of micro- and long non-coding RNAs are described and related to the six hallmarks of cancer. Recently, ncRNAs discovered in body fluids have become known as one of the most promising groups of oncological bioma [...]

by José C. Conesa

Received: 29 November 2021;  Published: 21 February 2022;  doi: 10.21926/cr.2201005

It is important to understand the band offsets between semiconductors, which are crucial to determine the direction of electron transfer at the interfaces. Two methods are normally used to determine the direction from the first principles: alternating slabs put in contact (without empty spaces between them) and separate calculations for each material surface in the presence of vacuum spaces. The first method may introduce distortions due to insufficient epitaxial match, which may lead to bandgap changes, and the se [...]

by Ezgi Cabuk Sahin  , Yildiz Aydin  and Ahu Altinkut Uncuoglu

Received: 17 May 2024;  Published: 02 September 2024;  doi: 10.21926/obm.genet.2403260

Molecular markers play a crucial role in accelerating crop production for sustainable agriculture by identifying resistant traits and enhancing genetic diversity. In this review, we examine the impact of the molecular markers on advancing our understanding of stress tolerance mechanisms in plants, addressing the pressing imperative to bolster global food production to meet the escalating demands of the growing population. Additionally, the application of molecular markers to evaluate the genetic accuracy of plants [...]

by Kyungmin Ko  , Juan F. Guerra  and David F. Garvin

Received: 29 August 2019;  Published: 28 October 2019;  doi: 10.21926/obm.transplant.1904089

Background: Graft site candidiasis is a serious complication after solid organ transplantation, often presenting as invasive arteritis leading to graft loss or even death. Case Report: We report a case of anastomotic site candidiasis leading to arterial rupture and death at postoperative day 10 with no clinical warning signs. Preservation fluid cultures were negative and postoperative Doppler ultrasonography did not show vascular compromise. Postmortem examination revealed microscopic arterial wall abscesses harbou [...]

by Gerhard Litscher

Received: 15 April 2020;  Published: 11 May 2020;  doi: 10.21926/obm.icm.2002030

In this technical report, we present for the first time a newly developed multimodal light-emitting diode (LED) pad for photobiomodulation (PBM). In order to demonstrate the range of possibilities for its application, we carried out a comparison of measurements with and without infrared (IR) LEDs in a volunteer, and are presenting the results. The pad consists of several components, which are mainly composed of LEDs of different modalities (IR, red, yellow, and blue). This multicolor system was applied to a periphe [...]

by Yiu Lin Wong  , Jialing Zhang  , Linda LD Zhong  , David Moher  and Zhaoxiang Bian

Received: 04 December 2023;  Published: 06 March 2024;  doi: 10.21926/obm.icm.2401018

The modified Jade Wind-Barrier formula (MJWB) may prevent the common cold in the elderly with a Qi-deficiency Constitution. Previously, no controlled trial evidence existed to illuminate the concept of “preventive treatment of disease” as outlined in the constitution theory of Traditional Chinese Medicine. This theory distinctly suggests that enhancing the Qi-deficiency Constitution and modulating its functional state can prevent the occurrence of the common cold. This controlled trial (ClinicalTrials.gov identifie [...]

by Monday Uchenna Obaji  , Angus Nnamdi Oli  and Malachy C Ugwu

Received: 12 December 2024;  Published: 23 April 2025;  doi: 10.21926/obm.genet.2502293

Cytokines are pivotal regulators of immune responses. They are critical in mediating inflammation, recruiting immune cells, and driving pathogen clearance. Among these, interleukin-6 (IL-6), interleukin-8 (IL-8), and tumor necrosis factor-alpha (TNF-α) stand out as key players in pediatric immunity, as they exhibit unique expression patterns that reflect the dynamic nature of the developing immune system. This review explores the dual roles of these cytokines in orchestrating immune defense and their potential as d [...]

by Sara Alattar  , Muhammad Nouman  , Chidozie Onyiuke  , Conrad Stasieluk  and Edwin Meresh

Received: 29 November 2023;  Published: 05 July 2024;  doi: 10.21926/obm.neurobiol.2403230

Studies have shown that decrease in time intubated is associated with better prognosis. Delirium is associated with increased duration of mechanical ventilation and Intensive Care Unit (ICU) length of stay. However, there is limited report on delirium in intubated seizure patients. As per report, low Glasgow Coma Scale (GCS) increased the risk of delirium and thus increasing ICU length of stay. Information on delirium and outcome in intubated seizure patients receiving lacosamide versus phenytoin is limited. Our re [...]

by Ken Shimomukai  , Haruka Maeda  , Zahirah binti Muhammad Azman  , Sandro Sitompul  and Goro Fujita

Received: 09 March 2023;  Published: 03 August 2023;  doi: 10.21926/jept.2303026

One way to increase solar photovoltaic penetration in the grid is the management of voltage fluctuations. This is because a photovoltaic plant cannot be interconnected to the grid if it causes voltage violations. Voltage violation is where voltage exceeds the acceptable range. Often, grid operators request photovoltaic plant owners to regulate voltage sufficiently with expensive and space-consuming static Var compensators. Unfortunately, this sometimes makes the project less feasible. This paper argues that there a [...]

by Christine A. Beamish  and Omaima M. sabek

Received: 08 November 2018;  Published: 05 March 2019;  doi: 10.21926/obm.transplant.1901055

Pancreatic islet transplantation holds promise for patients with insulin-dependent diabetes, but is severely limited by a shortage of cadaveric donor islets, and more so because of stringent inclusion criteria for organ donation including donor metabolic function, age, and comorbidities. The impact of these diverse factors on islet health has led to a broad investigation of global influences on islet biology, not least of all, characterization of mature, functional cellular identity and maintenance of appropriate e [...]

by Rama Bindu Manchikalapudi

Received: 31 May 2017;  Published: 28 September 2017;  doi: 10.21926/obm.transplant.1703005

Cardiac allograft vasculopathy is one of the leading causes of death following the first 5 years after orthotopic heart transplantation along with late graft failure, likely secondary to undiagnosed CAV. Currently there is no single medical treatment available for this condition except modification of risk factors and immunosuppression. Retrasplantation remains the hope for this entity with some limitations.

by Frenny Sheth  , Thomas Liehr  , Kristin Mrasek  , Joris Andrieux  , Stuti Tewari  , Naznin Lubna  and Jayesh Sheth

Received: 23 March 2018;  Published: 07 September 2018;  doi: 10.21926/obm.genet.1803033

Background: Small supernumerary marker chromosomes (sSMC) are rare cytogenetic findings in general, but especially in Turner syndrome so called sSMCT in a karyotype 46, X, +mar are even more scarce. According to the literature, sSMCT are derived from one of the Y-chromosomes in ~70% of the cases. Thus, to identify the presence of Y-chromosomal material is imperative, since these cases have an increased risk of gonadoblastoma deriving from the streak gonads. Methods: A 24-year-old short statured male presented with [...]

by Rodrigo Alvaro Brandão Lopes-Martins  , Patrícia Sardinha Leonardo  and Kevin Mannoia

Received: 04 March 2025;  Published: 18 June 2025;  doi: 10.21926/obm.icm.2502025

This article examines the complex relationship between the autonomic nervous system, the prefrontal cortex, and spiritual life, providing an interdisciplinary analysis in light of Galatians 5:16-25. Through a combination of theological reflection and insights from neuroscience, it explores how spiritual practices, such as meditation and prayer, influence emotional regulation, impulse control, and overall well-being. Studies in neuroscience have shown that regular spiritual practice can lead to measurable changes in [...]

by Patricia Lynn Dobkin

Received: 23 April 2018;  Published: 02 July 2018;  doi: 10.21926/obm.icm.1803013

Objectives: Living with any chronic pain condition is a challenge that can be met when one reduces reactivity to the sensory and evaluative aspects of it. The aim of this case study is to show how a clinical psychologist with expertise in chronic illness applied Buddhist principles to her own experience. Methods: When one realizes that suffering is the combination of pain plus resistance then one can learn how to accept rather than exacerbate it. Applying the Four Noble Truths from Buddhist psychology to understand [...]

by M. Robyn Andersen  , Kelsey Afdem  , Marcia Gaul  , Shelly Hager  , Erin Sweet  and Leanna J. Standish

Received: 27 February 2019;  Published: 26 July 2019;  doi: 10.21926/obm.genet.1903087

Patients’ lay theories about the cause of their cancer may influence patient behavior and adjustment, they have also been found to differ substantially from scientific evidence of cancer risk factors. This report describes beliefs about genetic causes of breast cancer, among 522 recently diagnosed breast cancer survivors participating in an observational study. Patients were asked to respond to an open-ended question about the cause of their cancer. Causes mentioned included family history, genetics, lifestyl [...]

by Igor Val Danilov  , Araksia Svajyan  and Sandra Mihailova

Received: 05 April 2023;  Published: 18 October 2023;  doi: 10.21926/obm.neurobiol.2304189

This pilot study (n = 19) examines fidelity rates of the new computer-aided method of diagnosing cognitive development delay in 3-to-6-year-old children. The small-scale research repeats the methodological components of the previous two studies, only changing the data collection process by introducing the baseline value (BV). Experimental data show a significant increase of 9.4 times in the shared intentionality magnitude in neurodivergent children. The results support the hypothesis that the bioengineering system [...]

by Marina Moguilevitch  and Tracey Straker

Received: 05 July 2020;  Published: 12 November 2020;  doi: 10.21926/obm.transplant.2004123

Clinical presentation and progression of Wilson’s disease can be diverse in different groups of patients. While young children most likely to present with acute or chronic liver failure, older children and adults may exhibit extrahepatic manifestation like neuropsychiatric, cardiac, renal, pancreatic and several others. Diagnosis of Wilson’s disease is based on the combination of specific clinical findings, laboratory and genetic testing. There are different modalities of treatment available for this condition. Liv [...]

by Olivia C Smibert  , Joseph S Doyle  , Adam WJ Jenney  , David Pilcher  , Miranda A Paraskeva  , Glen P Westall  and Greg I Snell

Received: 16 September 2020;  Published: 13 January 2021;  doi: 10.21926/obm.transplant.2101134

Since 2018 The American Society of Transplant has recommended that Hepatitis C Virus seropositive positive, non-viremic donors (HCVAb+/NAT-) be considered non-infectious and safe for transplantation. This report describes clinical outcomes and HCV serological and virological outcomes following lung transplantation (LTx) utilizing such donors. This retrospective cohort study describes seven HCVAb+/NAT- donors used for bilateral LTx. Donor information was sourced from the national organ donation service and recipient [...]

by Aline Duarte Folle  , Kimberly C Paul  , Cynthia D Kusters  , Jeff M Bronstein  , Adrienne M Keener  and Beate Ritz

Received: 30 June 2020;  Published: 26 August 2020;  doi: 10.21926/obm.geriatr.2003131

Insomnia and excessive daytime sleepiness are the most common sleep disturbances in Parkinson’s disease. This study aims at better understanding how severity of PD motor and non-motor features and dopaminergic treatments contribute to these sleep symptoms in the first decade of PD. Data from a community-based cohort of PD patients was used to model cross-sectional PD-related risk factors for insomnia and EDS sleep scores using linear regression models adjusted for age, gender, and PD duration. Longitudinal changes [...]

by Shih-Ang Hsu

Received: 25 July 2021;  Published: 02 September 2021;  doi: 10.21926/aeer.2103022

Spatial relation between wind stress and storm surge during two hurricanes in 2020 is investigated. It is found that, during Laura’s landfall, the area inside of 65 knots (34 m s -1) isotach or line of equal wind speed can produce up to 18 ft (5.5 m) inundation and during Delta, the area inside of 50 knots (26 m s -1) up to 11 ft (3.3 m) high water level above the ground. The tropical cyclone (TC) surface analysis near landfall by the Regional and Mesoscale Meteorology Branch (RAMMB) is recommended as a first [...]

by Aarthi Madhavan  , Isaac Sia  , Giselle Carnaby  and Michael Crary

Received: 29 October 2020;  Published: 22 February 2021;  doi: 10.21926/obm.geriatr.2101158

Individuals with acute stroke on nonoral feeding regimens frequently develop pneumonia, questioning the long-held belief that pneumonia in stroke patients is a caused by food and liquid aspiration alone. Refluxate and colonized oral secretions are thought to contribute to an acidic oropharyngeal environment. If aspirated, these colonized oral secretions with increased acidity, can result in increased risk to the respiratory system. This study aimed to investigate the relationship between pharyngeal acidity, dysphag [...]

by Boel De Paepe

Received: 28 February 2019;  Published: 16 May 2019;  doi: 10.21926/obm.genet.1902079

In order to successfully recover from damage, skeletal muscle tissue requires proper activation of a tightly orchestrated repair program. Non-coding RNAs actively participate in this complex process of demolition and rebuilding. In this review, the contribution of dysregulated non-coding RNA expression to disease-associated pathological changes is explored in hereditary muscular dystrophies and idiopathic inflammatory myopathies. Disturbances in spatiotemporal expression of non-coding RNAs appear to be key factors [...]

by Jéssica A.P. Ponciano  and Marcelo S. Batista

Received: 01 December 2021;  Published: 26 January 2022;  doi: 10.21926/cr.2201002

In this paper, the relationship between activity and structure of Cu2+ in different chemical environments of Cu-BETA, La2CuO4, and CuO nanocatalysts was systematically investigated for acetonitrile combustion. The study revealed that exchanged and octahedral species of Cu2+ coexist in Cu-BETA, while octahedral species are dominant in CuO and La2CuO4. All nanocatalysts achieved high conversion rates of acetonitrile, which rapidly increased with temperature. CuO and La2CuO4 led to the formation of undesired products [...]

by Victoria Lorenzetti  , Elena Bargagli  , Antonella Fossi  , David Bennett  , Paolo Cameli  and Paola Rottoli

Received: 30 August 2018;  Published: 18 December 2018;  doi: 10.21926/obm.transplant.1804033

Background: Alpha-1-antitrypsin (AAT) deficiency is the most common hereditary disorder in adults and is associated with an increased risk of developing lung emphysema. Methods:Here, we report the case of a 54-year-old man, who underwent bilateral lung transplantation due to AAT deficiency emphysema in the general hospital of Siena, Italy. Results:The patient was diagnosed with partial AAT deficiency (189 mg/dL) associated with the PIMZ genotype; although he quit smoking, his lung disease progressed to chronic resp [...]

by Koorosh Goudarzi  and AliReza R. Taghizadeh

Received: 31 December 2022;  Published: 06 February 2023;  doi: 10.21926/jept.2301006

In this paper, due to the importance of energy recovery from internal combustion engines and the increasing human growing need for power and refrigeration, a two-cycle power and refrigeration system consisting of an organic Rankine cycle and an ejector refrigeration cycle is investigated analytically. The proposed system with the ability to use the ejector as an effective and economical system, can produce simultaneous power and refrigeration by drawing thermal energy from the exhaust gas and engine coolant in the [...]

by M Wehming  , A Briem-Richter  , R Ganschow  , F Brinkert  , B Winkler  , L Fischer  and Enke Grabhorn

Received: 07 June 2020;  Published: 25 January 2021;  doi: 10.21926/obm.transplant.2101135

Some malignancies such as hepatoblastoma may be an indication for liver transplantation (LT) or some, for example, post-transplant lymphoproliferative disease (PTLD) may develop after successful LT. An immunosuppressive therapy after LT can promote the recurrence of the primary malignancy. The mammalian target-of-rapamycin inhibitors (mTORi) are immunosuppressive agents with anti-tumor properties. We examined the impact of everolimus (EVL) together with calcineurin inhibitors on allograft outcome and patient surviv [...]

by Oliver Reed  , Patrick B Allen  , Grant Caddy  , John Eccles  and Tony CK Tham

Received: 28 January 2019;  Published: 26 March 2019;  doi: 10.21926/obm.hg.1901015

Crohn’s disease is a chronic inflammatory condition of the gastrointestinal tract which can result in luminal stenosis and up to 90% of patients requiring surgery during their lifetime. Medical management aims to reduce the inflammatory burden to prevent the development of inflammatory strictures, progression to fibro-stenosis and subsequent obstructive symptoms. Endoscopic balloon dilatation (EBD) is a well-established, safe technique in the management of short strictures to prevent patients having multiple surgic [...]

by Deborah H. John  , Patrick Abi Nader  and Katherine Gunter

Received: 29 October 2018;  Published: 06 January 2020;  doi: 10.21926/obm.geriatr.2001098

Physical inactivity is the fourth leading risk factor for global mortality and as such, it is critical that physical activity guidelines for health consider equitable access to physical activity opportunities for all, including those aged 65 years and older. The purpose of this study was to examine the intersections of attributes of older people (e.g. income, gender, age, health, physical activity) and attributes of the places they live (e.g. rurality, public transit, sidewalks, parks, community centre) to explain [...]

by Xiang-Yu Sun  , Ping-Hong Jhou  , Min-Ze Lu  and Chang-Ming Liaw

Received: 25 February 2021;  Published: 22 June 2021;  doi: 10.21926/jept.2102028

This paper presents the development of a wind Interior Permanent-Magnet Synchronous Generator (IPMSG) based bipolar DC microgrids along with various switch-mode rectifiers. Firstly, the wind IPMSG is established and adequately controlled to possess satisfactory generating characteristics during different driven speeds and loads. Later, the boost switch-mode rectifier (SMR) based bipolar DC bus is established. Further, three-phase single-switch (3P1SW) boost SMR, three-phase two-switch (3P2SW) three-level boost SMR, [...]

by Hiromi Matsuhashi

Received: 28 April 2022;  Published: 06 June 2022;  doi: 10.21926/cr.2202015

Solid base catalysts consisting of MgO modified with 10 mol% ZnO (ZnO/MgO) were prepared by depositing zinc(II) acetylacetonate (Zn(acac)2) in polar and nonpolar organic solvents on the surface of MgO and Mg(OH)2. The process was followed by thermal decomposition in air at 773 K over a period of 3 h. The activity of MgO modified with Zn(acac)2 for base-catalyzed retroaldol reaction (the decomposition of diacetone alcohol (4-hydroxy-4-methyl-2-pentanone) to acetone) at 299 K was higher than the activity of unmodifie [...]

by Yi-Chia Liao  , Chun-Hway Hsueh  and Wen-Shin Lee

Received: 16 May 2020;  Published: 15 June 2020;  doi: 10.21926/rpm.2002014

Inspired by the application of metallic glass sheet as face material for improving the performance of golf clubs, the present work was aimed to explore the application of thin-film metallic glass (TFMG) coatings for enhancing the performance of strings. In order to achieve this aim, badminton strings were coated with TFMG coatings of different thicknesses. The compositions of these TFMG coatings were analyzed using an electron probe micro-analyzer. The amorphous structure of the film was verified using X-ray diffra [...]

by Omid Ranjbar Pouya  , Ahmad Byagowi  , Debbie M. Kelly  and Zahra Moussavi

Received: 20 August 2018;  Published: 27 June 2019;  doi: 10.21926/obm.geriatr.1902059

Background: Previous studies have reported that coordinate information (i.e. distance between any two objects in a specific direction) is encoded differently from Virtual Reality (VR) and physical scenes. However, the accuracy of encoding categorical information (i.e. relative positions of objects) from VR scenes has not been adequately investigated. During this study, we used a novel rotating visual scene to study the effects of aging, prior experience with VR, and dementia on the accuracy of encoding categorical [...]

by Ian Macreadie  and Sudip Dhakal

Received: 05 May 2019;  Published: 17 July 2019;  doi: 10.21926/obm.geriatr.1903064

The yeast, Saccharomyces cerevisiae, the model eukaryote, has provided much understanding of molecular and cellular biology, as well as insights into many human diseases. In this paper we review how yeast studies are contributing to knowledge about the role of oxidative damage to cell health, and how one of the key players in Alzheimer’s disease, amyloid beta (Aβ) is linked to the reactive oxygen species response involving AHP1, which encodes an alkyl hydroperoxidase, Ahp1p, a protein involved in protect [...]

by Stefan Hardy Lung  and Thomas Lung

Received: 30 November 2024;  Published: 14 April 2025;  doi: 10.21926/obm.geriatr.2502307

Cellular senescence (aging) is a physiological process that plays a role in tissue remodeling, wound healing, and embryogenesis. Prolonged senescence of cells can have detrimental effects and trigger a secretory phenotype (SASP, senescence-associated secretory phenotype), degenerative disorders, cancer, and age-related diseases. Suitable biomarkers and a range of different laboratory methods are used to investigate these complex relationships in vitro and in vivo. Since a universal biomarker for cell senescence has [...]

by Katrine Hygum  , Jakob Starup-Linde  , Torben Harsløf  and Bente Langdahl

Received: 29 August 2019;  Published: 04 December 2019;  doi: 10.21926/obm.geriatr.1904090

Background: The increased risk of fractures in individuals with diabetes has been underestimated by conventional fracture predictors such as the bone mineral density T-score or the Fracture Risk Assessment Tool. The present study conducted a systematic review and a meta-analysis to investigate the association between the levels of bone turnover markers (BTMs) and fractures in patients with diabetes. Methods: We conducted a systematic literature search. Eligibility criteria were studies investigating BTMs in patient [...]

by Joseph S. D'Arrigo

Received: 26 December 2019;  Published: 28 February 2020;  doi: 10.21926/obm.geriatr.2001110

Aging, hypertension, diabetes, obesity, atherosclerosis, traumatic brain injury, and other factors can all synergistically promote diverse pathological mechanisms. These risk factors trigger widespread inflammation and oxidative stress, both of which can lead to blood-brain barrier (BBB) disruption. These pathological cascades lead to neuronal Ca2+ increase, neurodegeneration, gradual cognitive/memory decline, and eventually Alzheimer's disease. In particular, more recent research indicates that chronic inflamm [...]

by Ashleigh Trapuzzano  , Sara Chizmar  , Lauren Wilda  and Nicole Dawson

Received: 03 April 2020;  Published: 27 September 2020;  doi: 10.21926/obm.geriatr.2003134

This study investigated the predictors of gait speed in community dwelling older adults while examining interplay between physical performance and cognition on comfortable and fast gait speed. Sixty-six community-dwelling older adults (mean age 80.8 71% female) completed the following: 30-Second Chair Stand (30-SCS), Functional Reach (FR), Flanker Task, Digit Symbol Substitution Test (DSST), and gait speed (comfortable and fast). Hierarchical linear regression examined the relationship of comfortable and fast gait [...]

by Sonal Mishra  , Neha Kumari  , Varsha K. Singh  and Rajeshwar P Sinha

Received: 18 January 2023;  Published: 03 August 2023;  doi: 10.21926/aeer.2303041

Cyanobacteria have great potential as a platform for biofuel production because of their fast growth, ability to fix CO2 gas, and genetic tractability. They also preserve the sustainability of an ecosystem without harming the environment. High-performance biofuels made from cyanobacteria can be utilized as a base for the production of green energy. Although a lot of studies have been conducted where plants and crops are used as the source of energy, cyanobacteria have been reported to have a more efficient photosyn [...]

by Robert Marx  and Lisa Burroughes

Received: 13 October 2018;  Published: 02 February 2019;  doi: 10.21926/obm.icm.1901009

Background: Training is generally not available for those wishing to deliver non 8 week Mindfulness Based Interventions (MBIs) adapted for specific contexts and populations. A new model for training in MBIs is developed with the following principle components: teaching on theory, participation in a practice, followed by teaching the practice and receiving feedback, and consultation and discussion of live mindfulness-based work. Methods: A quantitative and qualitative evaluation is presented of the experience of the [...]

by Giuseppe Cocco  and Philipp Amiet

Received: 05 February 2020;  Published: 19 March 2020;  doi: 10.21926/obm.geriatr.2001111

The present article summarizes the current state of understanding in geriatric cardiology in terms of the main developments in the field. The focus of the present review is on the therapeutics, into the specific characteristics of the elderly pa­tients dealing with the prevention of arterial hypertension, bradycardic arrhythmias, atrial fibrillation, coronary artery syndromes, valve heart diseases, and heart failure. Progress in the field of medicine has rendered possible to treat lethal cardiac diseases in the [...]

by James David Adams

Received: 14 January 2018;  Published: 19 December 2018;  doi: 10.21926/obm.icm.1804035

Background: This study presents several case reports of chronic pain patients treated with two different plant medicines from the Chumash Indian tradition. Methods: Patients suffering from self-reported fibromyalgia, chronic back pain, chronic bursitis, chronic tendinitis and other conditions were treated. California sagebrush (Artemisia californica) was grown by the author and made into a liniment. The liniment was applied to painful sites on the skin. Black sage (Salvia mellifera) was made into a sun tea. Chronic [...]

by Patrick Hagen  , William Adams  , Shruti Singh  , Shuai Qin  , Loredana Campo  , Stephanie Tsai  , Nasheed Hossain  , Scott E Smith  and Patrick J Stiff

Received: 04 November 2020;  Published: 07 February 2021;  doi: 10.21926/obm.transplant.2101136

Allogeneic stem cell transplantation remains the only curative option for many hematological malignancies. Umbilical cord blood (UCB) is an alternate donor source with potentially increased morbidity in elderly patients. We evaluated outcomes in alternate donor sources, prior to the initiation of haploidentical transplantation at our institution, of matched unrelated donor (MUD) and UCB in elderly patients (mean age 64, range 60-75). One hundred and eighty-four patients were included (MRD: 57; MUD: 69; UCB: 58). Th [...]

by Myriam Rudaz  , Thomas Ledermann  , Michael P. Twohig  and Michael E. Levin

Received: 24 May 2019;  Published: 10 October 2019;  doi: 10.21926/obm.icm.1904059

Background: There is robust evidence that mindfulness trainings enhance mindfulness as operationalized in Western psychology, but evidence about their effect on aspects of heartfulness is sparse. The present study, therefore, sought to evaluate whether a brief mindfulness training enhances heart qualities, including self-compassion, gratitude, and the generation of feelings of happiness. Methods: Eighteen students enrolled in a mindfulness training that was offered as part of an interdisciplinary class. The trainin [...]

by Ondřej Roubal

Received: 06 February 2023;  Published: 10 May 2023;  doi: 10.21926/obm.geriatr.2302235

This research study addresses certain theoretical issues surrounding the relationship between digital technologies, the aging population, and identity. At the same time, it offers a conceptual proposal of indicators of the social inclusion of older people in the digital culture of society as a potential starting point for further empirical research. The progressive trend of a growing proportion of older people is a demographic reality in many economically and technologically advanced societies. This demographic agi [...]

by Alessandro Luigi Rossi  , Vincenzo Capilupi  , David Palombo  , Luigi Tagliatesta  , Tecla Terenzio  , Marco Vitali  and Matteo Chiapasco

Received: 29 April 2019;  Published: 30 August 2019;  doi: 10.21926/obm.hg.1903035

OBJECTIVES To review current literature analysing possible secondary complications in response to the administration of paracetamol and codeine as analgesics in the dental field. To discuss a case of secondary acute pancreatitis triggered by the administration of both active ingredients. MATERIALS AND METHODS A 28-year-old patient, without any pancreatic or hepatobiliary condition was diagnosed with acute pancreatitis 3 hours after taking paracetamol 500mg and codeine 30mg prescribed as pain-relief therapy after ex [...]

by Ivan Y. Iourov  , Svetlana G. Vorsanova  and Yuri B. Yurov

Received: 29 May 2018;  Published: 15 August 2018;  doi: 10.21926/obm.genet.1803028

Runs of homozygosity (ROH) are uninterrupted contiguous regions within the genome exhibiting allelic homozygosity (alleles are inherited from the same parent). Genome-wide analyses consistently demonstrate that megabase-scale ROH are ubiquitous in humans, reflecting individual demographic history. The number and length of ROH correlate increasingly with the degree of consanguinity and can be associated with genetic diseases in both inbred and outbred individuals. Genomic imprinting and uniparental disomy (UPD) are [...]

by Mª Carmen Márquez

Received: 27 March 2024;  Published: 18 July 2024;  doi: 10.21926/cr.2403009

Lipase-catalyzed hydrolysis of olive oil has been studied in the absence of emulsifier. A simple mathematical model to predict the hydrolysis rate is derived from a proposed kinetic mechanism of the reaction. The hydrolytic reaction obeys Michaelis-Menten kinetics with a simultaneous second-order enzyme deactivation. The model predictions closely agree with the experimental results.

by Jessica R Turnbull  , Jenna Vyas-Lee  and Sally Hobson

Received: 17 November 2020;  Published: 06 May 2021;  doi: 10.21926/obm.neurobiol.2102094

Sleep-related difficulties are common in children with neurodevelopmental disabilities. Poor sleep health is associated with detrimental impacts not only for the child/young person, but also their family members. Exercise is considered to be important for sleep health, improving duration and quality of sleep in adult studies, however there is limited literature on impact in children with neurodevelopmental disabilities, and barriers to participation exist for this group. We set out to test the feasibility and accep [...]