Narrative Review of Surgery for Myasthenia Gravis
Abstract
1617 12359
Narrative Review of Surgery for Myasthenia GravisAbstract
Myasthenia Gravis (MG) is a rare autoimmune disorder characterized by antibody mediated blockade of neuromuscular transmission. Up until the last decade, evidence suggesting benefit of thymectomy for myasthenia gravis has been based on non-randomized control studies. Our paper serves as an expert narrative review of new literature pertaining to surgical management of myasthenia gravis based on review of articles from PubMed and Cochrane database from date of inception through June 14, 2021. We used the MeSH search [...] 1617 12359 |
The Reliability of Willingness-to-Pay Responses in the Contingent Valuation Method: A New Single-Sample ApproachAbstract
The Contingent Valuation (CV) Method, like other stated preference techniques, seeks to measure economic preferences for public goods. Throughout the development and application of this non-market procedure, the accuracy of the measured preferences has been front-and-centre among practitioners and potential users. The most important issue of debate has been the extent to which the method can reliably measure economic preferences. In this article, a new methodology is described that enables multiple indicators of la [...] 1424 12356 |
A Review on the Ethnomedicinal Plants Used in Zimbabwe for the Treatment and Management of Skin Conditions: Perspectives on Pharmacological and Toxicological Evaluationby
Abstract
Medicinal plants remain central to healthcare in Africa, where up to 80% of the population relies on traditional remedies to manage a range of health conditions, including skin ailments. In Zimbabwe, the country's rich biodiversity and favourable agroecological zones support a diverse range of ethnomedicinal plants. However, much of the knowledge surrounding these plants remains dispersed and scientifically under-evaluated. This review consolidates evidence from ethnobotanical surveys, peer-reviewed research, and g [...] 1695 12355 |
Integrating Mindfulness and Physical Exercises for Medical Students: A Systematic Reviewby
Abstract
Background: The purpose of this systematic review was to appraise the empirical evidence pertaining to medical students and the integration of mindfulness and physical exercise regimens. Methods: A systematic review was undertaken. Five databases were used to survey the salient literature. Results: The initial search identified 353 potentially relevant articles of which 17 articles were considered for the final review. The findings indicated that the research was mainly conducted in the USA with some research origi [...] 2184 12350 |
A Qualitative Study Comparing the Experiences of the Meditation-Based Lifestyle Modification Program with Multi-professional Psychiatric Treatment for Female Outpatients with Mild to Moderate DepressionAbstract
Meditation-Based Lifestyle Modification (MBLM) is a complex eight-week mind-body intervention based on the traditional eight-fold path of classical yoga. MBLM was developed for mental health care, and it combines ethical living, physical yoga, and meditation. In this qualitative study, the subjectively perceived efficacy of MBLM was compared to the perceived efficacy of an individually tailored, multi-professional psychiatric treatment (MPT) in a psychiatric outpatient clinic. Twelve patients were interviewed for t [...] 1926 12344 |
Effects of Quantum Confinement of Hydrogen in Nanocavities – Experimental INS Results and New InsightsAbstract
Current developments of non-relativistic quantum mechanics appear to predict, and reveal, counter-intuitive dynamical effects of hydrogen in nanostructured materials that are of considerable importance for basic research as well as for technological applications. In this review, the experimental focus is on H2O and H molecules in carbon nanotubes and other nanocavities that have been experimentally investigated using the well-established technique of incoherent inelastic neutron scattering (INS). For instance, the [...] 2216 12344 |
Beyond CPRA: Identifying Sensitized Kidney Candidates with Markedly Low Access to Deceased Donor Transplantation by Granular CPRA and Blood Typeby
Abstract
Prioritization in the US Kidney Allocation System (KAS) has led to an improvement in the rates of transplantation in highly sensitized (HS) patients. However, there is a subset of HS patients who are at a disadvantage, despite prioritization under KAS. The purpose of this study was to describe the transplant rate (TR) by calculated panel reactive antibody (CPRA) of HS candidates before and five years post-KAS to characterize their access to deceased donor transplants and quantify the number of HS candidates who are [...] 2146 12342 |
Assessment of Mineral Gain in White Spot Lesions Using CPP-ACP and CPP-ACFP in Different Clinical Protocols: A Proof of Concept Studyby
Abstract
Subsurface remineralization can be promoted by the topical application of nanoparticles of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP). To assess changes in enamel white spot lesions, an in situ proof-of-concept investigation was performed using 5 subjects (all of whom were healthy young adults) with a cross-over study design. Custom orthodontic brackets were attached to the buccal surfaces of the maxillary second premolar and first molar teeth. Each bracket had a recess that held a slab of enamel w [...] 1523 12334 |
Incidence, Location, and Natural History of Perihepatic Fluid Collections after Orthotopic Liver TransplantationAbstract
Objective: The purpose of this study was to evaluate the common locations of perihepatic fluid collections after liver transplantation, assess their complexity, and understand their natural history and clinical significance.
Materials and Methods: A retrospective analysis of 189 postoperative orthotopic liver transplant patients with a mean age 49.6 years was performed using serial CT or MRI to characterize perihepatic fluid collections. Location, size, complexity of the collections, and clinical course were evalua [...] 1566 12330 |
Recent Progress in the Development of Molecular Electrocatalysts for Formate Oxidationby
Abstract
Fuel cells based on renewable synthetic fuels are promising alternatives to fossil fuel combustion for efficient electricity production. Much focus has been placed on hydrogen as a chemical fuel, but being a flammable gas, there are challenges with its safe handling. Formic acid is an attractive liquid fuel for use in direct formic acid or formate fuel cells, and it can in principle be produced from the thermal or electrochemical reduction of carbon dioxide. Over the past ten years, advances have been made in the d [...] 1815 12326 |
Identification and Prioritization of Causal Variants of Human Genetic Disorders from Exome or Whole Genome Sequencing Databy
Abstract
Background: With genome sequencing entering clinics as a diagnostic tool to detect genetic disorders, there is an increasing need for bioinformatics-based solutions that enable precise causal variant identification in a timely manner. Workflows for the identification of candidate disease-causing variants usually perform the following tasks: i) identification of variants; ii) filtering of variants to remove polymorphisms and technical artifacts; and iii) prioritization of remaining variants to provide a small set of [...] 2063 12324 |
From Killer to Solution: Evaluating Bioremediation Strategies on Microbial Diversity in Crude Oil-Contaminated Soil over Three to Six Months in Port Harcourt, NigeriaAbstract
The study aimed to evaluate the efficacy of various bioremediation approaches on microbial diversity in crude oil-contaminated soil over three to six months in Port Harcourt, Nigeria. The objective was to assess the impact of different bioremediation strategies on microbial populations, particularly focusing on hydrocarbon-utilizing bacteria and fungi. Microbial populations were quantified using serial dilution and microbial count techniques. The vapor phase transfer mechanism was employed to estimate hydrocarbon-u [...] 1708 12311 |
Positive Life Experiences Following a Dementia Diagnosisby
Abstract
Background: Given the stigma and fear associated with Alzheimer’s disease (AD), combined with the progressive nature of the disease, the diagnosis of AD or mild cognitive impairment (MCI) is often very difficult; yet, there may still be ways to experience some positive outcomes following diagnosis. We aim to assess the psychological impact of a diagnosis of MCI or early dementia on positive well-being. Methods: Individuals with a diagnosis of MCI or AD were mailed surveys with the Silver-Lining Questionnaire. Resul [...] 1903 12307 |
Newborn Screening in Gaucher Disease: A Bright and Complicated FutureAbstract
Gaucher disease (GD) is one of the most common lysosomal storage disorders resulting from biallelic mutations in the GBA1 gene, causing a dysfunction of the lysosomal hydrolase, glucocerebrosidase (acid-β-glucosidase; E.C 3.2.1.45). Clinical manifestations are heterogenous and can include splenomegaly, anemia, and neurological impairments in the case of neuronopathic Gaucher disease types 2 and 3. Newborn screening, arguably the most important public health initiative to date, has been regularly conducted on n [...] 1519 12302 |
Micromechanics-Based Modeling of SiC/SiC Ceramic Matrix Composites and StructuresAbstract
The behavior and response of ceramic matrix composites (CMCs), in particular silicon carbide fiber reinforced silicon carbide matrix (SiC/SiC), is affected by many factors such as variation of fiber volume fraction, residual stresses resulting from processing of the composites at high temperature, random microstructures, and the presence of matrix flaws (e.g., voids, pores, cracks etc.) as well as general material nonlinearity and heterogeneity that occurs randomly in a composite. Residual stresses arising from the [...] 1792 12302 |
HLA Typing and Donor-Specific Antibody Screening in Kidney Transplantation: Bridging the Past to the Futureby
Abstract
Human leukocyte antigens (HLA) are unique proteins expressed on the surface of human cells, playing a pivotal role in the immune system, particularly in the contexts of infection, cancer, and transplantation. The widespread adoption of HLA typing methods has become an essential component in assessing donor-recipient compatibility, a crucial limiting factor in solid organ transplantation. In general, the greater the disparity between a donor's and recipient's HLA types, the higher the likelihood of provoking an allo [...] 1492 12298 |
Innovative Strategies and Challenges for the Prevention of Pathological Anxiety in Children and AdolescentsAbstract
The effects of pathological anxiety on public health have led to the realization that anxious children might experience significant limitations in their lives. Evidence-based cognitive-behavioral (CB) interventions are now being implemented in schools at a group level to combat anxiety.Childhood emotional health should be considered a national and global priority for an effective strategy promoting the prevention of mental health. The aim of this study is the description of novel data on the effectiveness of preven [...] 1332 12275 |
Voice and Speech Disorders in Alzheimer’s Disease: A State-of-the-Art ReviewAbstract
Alzheimer’s disease is the most common type of dementia in the world. This manuscript attempts to review the current knowledge of neurolaryngology and speech and language therapy in Alzheimer’s disease in order to distinguish it from other neurodegenerative diseases. Only a limited number of studies carried out on Alzheimer’s disease patients with speech or laryngeal disorders are found in the literature. Laryngeal (dysphonia, dysphagia, dry mucosa…) and speech symptoms (aphasic, rhythm alterations…) appear to exis [...] 1929 12264 |
Analysis of Surface Water Areal changes using Remote Sensing Databy
Abstract
Inland water bodies are crucial for supporting human life in various parts of the world. Therefore, it is essential to accurately monitor its spatiotemporal variations for better water management. The main objective of this study is to investigate the application of remote sensing data for quantifying the surface area changes and the impact of climatological variabilities over Lakes Mead and Chapala. Historical time series of monthly surface area dynamics were developed using Landsat 1-8 scenes and the climate vari [...] 1766 12251 |
Telomere Editorial - Perspectives on Telomeres and AgingAbstract
Telomere Editorial-Perspectives on Telomeres and Aging 1954 12236 |
Performance Investigation of a Nickel Cermet Anode Modified with Copper, Alkaline Earth Metal Oxide, Boron, and Perovskite for Direct Methane Fuel CellAbstract
The metallic copper, alkaline earth metal oxide, boron, and perovskite were incorporated on the surface of a Ni-cermet anode, and the performance of the modified Solid Oxide Fuel Cell (SOFC) anode was evaluated. The cell performance was analyzed by voltage-current characteristics (V-I curve) and H2-CH4 step reactions (P-t curve) in a potentiostatic mode. Besides, we also determined if a metallic phase or high electronic conductivity of the anode is important for a cell to perform well when H2 is used as a fuel, whe [...] 2163 12232 |
Cognitive Impairment, Meditative Movement, and Gene Expression in Breast Cancer Survivorsby
Abstract
Breast cancer survivors (BCSs) report decrements in cognitive functioning. A Meditative Movement (MM) program (Qigong/Tai Chi Easy) combines meditation and exercise, practices known to improve cognitive function. Method: Using a single group, pre- to post-intervention assessment design, a pilot study was conducted in BCSs to test the effects of an 8-week MM intervention on cognitive functioning, sleep and mood and to explore changes on selected gene expression factors, BDNF, NF-kB1, and TP53, expected to improve wi [...] 1872 12230 |
NIR Spectroscopy and Aquaphotomics Approach to Identify Soil Characteristics as a Function of the Sampling DepthAbstract
Soil is a very complex medium made of minerals, organic matter, microorganisms, air, and water. Vibrational spectroscopy techniques are exceptionally well-suited to be used with portable and hand-held devices. In this study, NIR spectroscopy was applied using portable instrumentation and the holistic Aquaphotomics approach to identify the differences in three Mediterranean soil profiles from Sardinia (Italy). The soil samples (95) collected from alluvial and loess-sampling sites in the three study areas of North Sa [...] 1515 12219 |
Green Synthesis of Metal-Organic Biohybrid (Mob) NanomaterialsAbstract
Green synthesis of nanomaterials endeavors to reduce the use of high energy methods with those that may include lower temperatures and pressures, use of natural products, and bottom-up self-assembly. Here we describe the generation of metal-organic biohybrids (MOBs) with nanoscale features synthesized at physiological (37°C) and room temperature (25°C). These MOBs utilized the naturally occurring amino acid dimer cystine as the biological component, and a series of metals, including copper, silver, and cobalt. The [...] 1556 12217 |
Impact of Pernicious Chemicals on Geopolymer and Alkali-Activated Composites Incorporated with Different Fiber Types: A ReviewAbstract
Over the past decade, developing geopolymer mixes to replace ordinary Portland Cement (OPC) composites has yielded positive results, leading to extensive research. The incorporation of fibers in geopolymers, besides impacting the mechanical properties, has also significantly impacted durability, mainly when dealing with the most pernicious forms of deterioration resulting from chloride attack, water penetration, sulfate attack, acid attack, as well as freeze-thaw, which occurred through chemical transgression. This [...] 1209 12210 |
Combination of the Hansemann-Boveri, Warburg, and Knudson Theories of Cancer, Based on Failure of Missegregation Damage MitigationAbstract
Hansemann-Boveri’s aneuploidy theory, the Warburg effect, and the Knudson hypothesis can be viewed as different aspects of a single theory of cancer. In this, the extremely common chromosome missegregation may be the underlying cause. Chromosome missegregation is mitigated via several mechanisms. Cancer can occur only when all of these mechanisms have been inactivated in a single cell line, typically by mutation. There are at least five different repair mechanisms, implying a hit-factor of at least five. These miti [...] 2132 12197 |
Research Progress in Enhancing Proton Conductivity of Sulfonated Aromatic Polymers with ZIFs for Fuel Cell ApplicationsAbstract
The escalating global temperatures and their adverse effects underscore the growing imperative for the widespread adoption of clean fuels, notably hydrogen. Proton Exchange Membrane Fuel Cells (PEMFC) emerge as a pivotal green energy technology, facilitating electricity and water generation. The optimization of PEMFC efficiency hinges on the judicious selection and fabrication of polymer membranes. Within innovative materials, Zeolitic Imidazolate Frameworks (ZIFs) represent a novel subclass within the expansive fa [...] 1662 12166 |
Nature Connection, Mindfulness, and Wellbeing: A Network AnalysisAbstract
Relationships between nature connection, mindfulness and wellbeing have been observed through nature based therapeutic interventions, where mindfulness and nature appear to reciprocally influence each other in relation to wellbeing and is potentially consistent with attention restoration theory. However, previous studies have relied on examining nature based interventions rather than the role of nature connection in everyday lives. This investigation explored the relationship between nature connection, mindfulness, [...] 1464 12159 |
Men's Bones Matter Too, a Cross Sectional Study Examining Bone Health among Men with Intellectual Disability in Ireland.by
Abstract
Globally between 30-40% of all osteoporotic fractures occur among men, with a quarter of all hip fractures, the most serious complication of osteoporosis, occurring in men. Among men of 50 years of age or older, osteoporotic fracture risk reaches an alarming 20%. What is of great concern is that associated mortality is greater among men when compared with women. For hip fractures specifically, mortality for men is two to three times that in women which may be attributed to the fact that osteoporosis is often consid [...] 1739 12154 |
Knight in Splicing Armor: Alternative Splicing as a Neuroprotective MechanismAbstract
By adjusting gene expression in response to environmental changes, cells can optimize fitness as needed. Alternative splicing is one of the most important post-transcriptional regulation steps, broadly involved in diverse physiological and pathological conditions. Here, we present 5 cases of alternative splicing conferring increased neuroprotection through diverse mechanisms. These examples highlight the enormous power of alternative splicing in maintaining viability of neurons. From pre-mRNA secondary structure al [...] 1919 12150 |
Sleep and Help Seeking Behaviours in Australia: A Narrative ReviewAbstract
Inadequate sleep is a largely under recognised problem in Australia despite researchers consistently highlighting it as a key component of health and wellbeing. Over a third of Australian adults now experience some form of inadequate sleep, which is consistently linked to a range of accompanying physical and mental health concerns. In addition to the health burden on the individual, the associated financial burden incurred by the community is extremely high with inadequate sleep costing over 66.3 billion annually i [...] 1508 12136 |
Neurochemical System Involved in Anorexia NervosaAbstract
Anorexia nervosa is a psychiatric disorder, the etiopathogenesis of which is still not fully understood. Currently, the most accredited model is a multifactorial model, which involves interaction between predisposing factors of biological nature, partly genetically determined, and psychological/personological and environmental socio-cultural factors. The last 20 years have led to the advancement in our knowledge on the mechanisms of energy homeostasis maintenance. There has been a veritable explosion of studies aim [...] 1454 12136 |
Machine Learning in Hazardous Building Material Management: Research Status and ApplicationsAbstract
Assessment of the presence of hazardous materials in buildings is essential for improving material recyclability, increasing working safety, and lowering the risk of unforeseen cost and delay in demolition. In light of these aspects, machine learning has been viewed as a promising approach to complement environmental investigations and quantify the risk of finding hazardous materials in buildings. In view of the increasing number of related studies, this article aims to review the research status of hazardous mater [...] 2184 12136 |
Genomic Biomarker Surveillance in the Care of Solid Organ Transplant Recipients: An Update for the General Clinician during the Coronavirus (CoVid-19) PandemicAbstract
Biomarker surveillance after solid organ transplant is an advancing field with promise for further elucidation through high-throughput analyses and “omics” technologies. To date, Gene Expression Profiling (GEP; AlloMapâ) is the only FDA-cleared genomic assay as surveillance for moderate-severe TCMR versus allograft quiescence after heart transplantation. Clinical validity and utility, however, have been recently established after kidney and heart transplantation, for analysis of donor-derived cell-free DNA in the a [...] 2081 12117 |
A Mixed Methods Approach to Understanding Conceptions of Mindfulness MeditationAbstract
Background: Mindfulness meditation (MM) is an increasing area of interest for health professionals and the general public alike. Beneficial outcomes are associated with this practice; however, definitions of mindfulness and meditation are varied, and anecdotal accounts suggest that people hold conceptions about the constructs. Furthermore, mindfulness has been incorporated into therapeutic modalities without much consideration for context, including the client’s previous experiences with and understanding of MM. To [...] 2013 12097 |
The Use of ECMO in Treatment of Post Liver Transplant Septic ShockAbstract
Liver transplant is a life-saving therapy for patients with end stage liver disease and liver cancer. Liver re-transplantation cases are usually more challenging and riskier than primary surgery, they require careful consideration and larger recourse utilization. Decision making on who receives transplantation surgery includes individual patient risks and benefits, physician judgment, specific transplant center policies, surgical experience, geographic organ availability, and ethical considerations. Several mathema [...] 1896 12091 |
Problems Associated with the Measurement of Neuropsychiatric Symptoms of DementiaAbstract
Neuropsychiatric symptoms (NPS) affect nearly all persons living with dementia (PLWD) at some point during the course of the disease. Given the absence of a cure or effective pharmacotherapy for dementia, it is particularly important to prevent, measure, track, and manage NPS in dementia care. Unfortunately, these efforts are hindered by inconsistent operational definitions and measurement tools for numerous neuropsychiatric symptoms. This review examines agitation, aggression, restlessness, and rejection of care a [...] 1967 12089 |
On the Relationship Between Teacher Stress, Student Age, and Social-Emotional Competenceby
Abstract
Stress in teaching leads to many teachers suffering from burnout or leaving the profession. Therefore, it is important to identify specific correlates of teacher stress. The role of student age and social-emotional competence in teacher stress emergence is still unclear To further clarify this relationship, 284 teachers were surveyed using a questionnaire that measured teacher stress, student year grade, and student social-emotional competence. Results show a strong negative relationship between grade level and tea [...] 1427 12072 |
Modeling Tile Drainage Outflow in Thin Agricultural Soils with Impermeable under Layer in Newfoundland and Labrador, Canadaby
Abstract
Subsurface tile drainage installation helps to maintain water table levels and to meet adequate crop moisture requirements. Artificial subsurface drainage continues to be a common practice in Newfoundland and Labrador (NL) and elsewhere around the world. The main objective of this study was to evaluate the performance of DRAINMOD in simulating water table depth (WTD) and water outflow from tile drained agricultural fields. This site on the Avalon Peninsula of Eastern Newfoundland has a rolling landscape with predom [...] 2122 12070 |
The Roles of Collagen in Islet TransplantationAbstract
Islet transplantation is a cellular replacement therapy for severe diabetes mellitus. Although the clinical outcome of islet transplant has been improving, the transplant efficacy of this treatment is not superior to that of pancreatic organ transplantation, a similar transplant therapy. Various factors have been characterized as ‘islet transplantation specific’, which includes lack of revascularization and ischemia, innate inflammation, or autoimmunity, affect the therapeutic outcome of this treatment. Among them, [...] 2102 12070 |
Adsorption of Phosphate by Synthesized Silver/Calcium Oxide-Activated Carbon NanocompositeAbstract
Developing adsorbents with appreciable morphology will create new approaches for better phosphate adsorption performance. This study aims to investigate the design of an adsorbent by impregnating silver nanoparticles (AgNPs) onto calcium oxide-activated carbon (CaO-AC). The Ag/CaO-AC nanocomposite was used as an adsorbent to remove phosphate. Batch adsorption studies were performed to evaluate the effects of adsorbent dose, initial phosphate concentration, contact time, and pH on removing phosphate from an aqueous [...] 2005 12058 |
FASD and Brain Development: Perspectives on Where We are and Where We Need to Goby
Abstract
Maternal consumption of alcohol (ethanol) during pregnancy can lead to life-long neurobehavioral and cognitive abnormalities in the offspring, collectively referred to as Fetal Alcohol Spectrum Disorders (FASD). Prenatal exposure to ethanol is one of the leading causes of non-genetic intellectual disability and FASD is an umbrella category that includes Fetal Alcohol Syndrome, Partial Fetal Alcohol Syndrome, Alcohol Related Birth Defects, and Alcohol Related Neurodevelopmental Disorder. Children with a history of&n [...] 1647 12058 |
Impact of the COVID-19 Pandemic Measures on the Number of Meals and the Types of Physical Activity of Adolescents: Cross-Sectional Study in Delhi, Indiaby
Abstract
COVID-19 greatly affected the lives of adolescents through restrictions such as less playtime, more screen time, and limited interaction with peers. In this study, we assessed the impact of the COVID-19 pandemic on the dietary and physical activity-related behavior of school students aged 10–16 years. This cross-sectional study was conducted with adolescents recruited from seven randomly selected private schools in Delhi, India, during 2021. A self-administered web-based survey was conducted to evaluate the behavio [...] 1989 12054 |
Fungal Laccase-Mediated Enhancement of the Bioactivity of Green Algae Extractsby
Abstract
Biomass derived from green marine macroalgae Ulva sp. is considered a rich source of bioactive compounds. In the present study, we demonstrate the increased bioactivity of a phenolic-rich extract derived from green marine macroalgae Ulva intestinalis after its treatment with fungal laccases from Trametes versicolor and Agaricus bisporus. The phenolic composition of the extract, before and after its enzymatic treatment, was determined through several analytical methods. Furthermore, the antioxidant, enzyme-inhibitor [...] 2103 12051 |
Advances in Nanocarriers for Drug Delivery in Dental TherapiesAbstract
Dental caries are one of the major causes of oral degeneration diseases. In order to treat dental-related diseases, it is often challenging and expensive. Recent literature has reported many advances in designing delivery systems utilizing polymers and novel biomaterials. Polymers play an important role in designing many nanoformulations like liposomes, polymeric micelles, polymeric nanoparticles, carbon-based nanoparticles, nano-hydroxyapatite, iron oxide, zirconia, silica, and silver nanoparticles were used to tr [...] 1635 12042 |
Classical and Quantum Models of Diffusionby
Abstract
The objective of the paper is twofold: first, to review the classical diffusion models and show the approximations at the origin of the parabolic character of the classical equations; second, to demonstrate a connection between the quantum and classical models of diffusion. As diffusion is inherently related to the motion of constituents, the consistent models are framed within the dynamics of mixtures. The derivation of diffusion equations is then determined based on the related, pertinent approximations. 2183 12038 |
Dementia: Aloneness, Social and Relational Engagement, and Psychological Growth in Familiesby
Abstract
Background: Minimal research investigates negative and positive perspectives of wellbeing in families, when a member with dementia is limited in their speech, or speech is absent.
Methods: Seeking to explore this phenomenon further, semi-structured interviews sought negative and positive subjective interpretations from 27 family carers (mild to profound dementia). Interviews explored the participants' experience of changing relational and social engagement when a family member lives with dementia. Data were analyse [...] 2109 12037 |
The Role of Massage in Bereavement: A Scoping Reviewby
Abstract
Background: Death is a universal human experience. The experience of grief is unique for each person experiencing it. There is emerging research on modalities that provide support for bereaved individuals including bereavement massage. There is limited information in the literature about the specific role that massage can play in supporting bereaved individuals. The aim of this scoping review is to explore the literature that reports on the use and outcomes of bereavement massage so that massage therapists, consume [...] 2362 12025 |
Light-Activated Local Drug Delivery From Hydrogels: Potential for GBM Treatmentby
Abstract
Following post-operative treatment, the vast majority of GBMs recur, usually within 2 cm of the tumor resection margin. Since these tumors seldom metastasize outside the CNS, improved localized therapies should prove beneficial. Drug delivery systems (DDS) that allow control over drug release by an externally applied energy, such as light, have the potential of improving the results of chemotherapy. Light-activated hydrogel DDS, implanted in the operative cavity formed by tumor resection, bypasses the blood brain b [...] 1730 12024 |
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