Table of Content

Open Access Editorial

Acknowlegement to Reviewers of OBM Integrative and Complementary Medicine in 2020

Received: 07 January 2021;  Published: 07 January 2021;  doi: 10.21926/obm.icm.2101001

Abstract

The editors of OBM Integrative and Complementary Medicine would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2020. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers receive a voucher entitling them to a discount on their next LIDSEN publication and can download a [...]

1624 6640

Open Access Original Research

Pentachlorophenol Effect on Auxin Production by Pseudomonas fluorescens GU059580 and Its Application in Wastewater Bioremediation

Received: 29 July 2022;  Published: 18 November 2022;  doi: 10.21926/rpm.2204024

Abstract

Bioaugmentation by Pseudomonas strains is widely used for the removal of pollutants in wastewater. In this study, we aimed to determine the removal of pentachlorophenol (PCP, 800 mg·L–1) in secondary wastewater by the bioaugmentation process. We determined the effects of using three surfactants, namely sodium dodecyl sulfate (SDS), cetyl-tri-methyl-ammonium bromide (CTAB), and Tween 80 for PCP removal. We determined the effect of the role of PCP surfactant for the biofilm and auxin production of the se [...]

1058 6621

Open Access Case Report

A Rare and Complex Case of Multifactorial Thrombotic Microangiopathy in A Kidney Transplant Recipient: Interplay Between Antibody Mediated Rejection, Tacrolimus Toxicity, Cytomegalovirus Disease and BNT162b2mRNA Vaccine

Received: 11 May 2023;  Published: 04 September 2023;  doi: 10.21926/obm.transplant.2303194

Abstract

Thrombotic microangiopathy (TMA) in kidney transplant recipients is uncommon and difficult to manage, often with poor graft outcomes [1]. This is a complex and interesting case of an older, highly sensitised kidney transplant recipient who presented with de novo post-transplant TMA in the setting of antibody mediated rejection (ABMR), with other drivers being tacrolimus toxicity, cytomegalovirus (CMV) infection and anti-SARS-CoV-2 BNT162b2 mRNA vaccination. This led to rapid, irrecoverable graft loss. 76-year-old f [...]

1097 6615

Open Access Editorial

A Healthy and Happy 2019

Received: 15 January 2019;  Published: 15 January 2019;  doi: 10.21926/obm.genet.1901059

Abstract

A healthy and happy 2019

1027 6614

Open Access Review

Advanced Endoscopic Techniques in the Evaluation and Treatment of Fibrostenotic Crohn's Disease

Received: 09 May 2019;  Published: 16 August 2019;  doi: 10.21926/obm.hg.1903033

Abstract

Crohn’s disease is characterized by chronic intestinal inflammation that can result in significant morbidity and loss of intestinal function over time. Many novel treatments for Crohn’s disease are being developed, but a significant portion of patients still requires surgical therapy for structuring or penetrating disease. While the utility of esophagogastroduodenoscopy and ileocolonoscopy in inflammatory bowel disease patients is well established, new endoscopic techniques are being developed to help evaluate prev [...]

1436 6611

Open Access Original Research

A Systems Biology Approach to Understanding Delirium Pathophysiology and Identifying Natural Compounds for Potential Therapeutic Purposes

Received: 30 October 2024;  Published: 14 March 2025;  doi: 10.21926/obm.neurobiol.2501276

Abstract

Delirium is an acute neurocognitive disorder marked by disruptions in attention, cognition, and awareness, particularly prevalent among older and critically ill patients. This study applies a systems biology framework to dissect the molecular underpinnings of delirium and evaluate natural compounds for potential therapeutic roles. Through bioinformatics analyses, key biomarkers related to delirium, including IL6, AKT1, JUN, APP, and PPARGC1A, were identified, implicating pathways tied to neuroinflammation, oxidativ [...]

1241 6598

Open Access Original Research

The Technology of Upward Capillary Formation of Waste for Creating a Deposit before Land Reclamation

Received: 08 June 2022;  Published: 27 September 2022;  doi: 10.21926/aeer.2203037

Abstract

Mineral resources in the subsoil are classified as exhaustible. One of the ways to potentially replenish the sources of mineral resources is presented in the materials of these studies. In this article, we studied the natural formation in the bowels of the array of zones of high concentrations of compounds of useful components. We aimed to develop the technological methods of mass transfer and directed deposition of useful components. The technological transition of mineral resource extraction from the “gathering” [...]

1114 6590

Open Access Editorial

Acknowlegement to Reviewers of Recent Progress in Materials in 2020

Received: 07 January 2021;  Published: 07 January 2021;  doi: 10.21926/rpm.2101001

Abstract

The editors of Recent Progress in Materials would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2020. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers receive a voucher entitling them to a discount on their next LIDSEN publication and can download a certificate o [...]

1094 6589

Open Access Original Research

Association between Liver Stiffness and Gastro-Esophageal Varices in Chronic Liver Diseases

Received: 12 November 2018;  Published: 27 December 2018;  doi: 10.21926/obm.hg.1804012

Abstract

Objective: Elastography is a non-invasive examination method that can estimate the extent of liver fibrosis, measured as liver stiffness (LS). We examined the relationship between gastro-esophageal varices and the LS and how to predict esophageal varices and varices bleeding by LS. Methods: From 2014 to 2016, we conducted a retrospective study of 138 subjects, all of whom were patients with chronic liver disease, including NAFLD, alcoholic liver disease, primary biliary cholangitis, viral hepatitis, and others. LS [...]

1245 6584

Open Access Case Report

Mosaic Potocki-Lupski Syndrome Due to a Supernumerary Marker Chromosome Containing RAI1

Received: 30 December 2023;  Published: 05 March 2024;  doi: 10.21926/obm.genet.2401220

Abstract

Potocki-Lupski syndrome (PTLS) is a recurrent microduplication syndrome characterized by developmental delay, behavioral abnormalities, mildly dysmorphic facial features, hypotonia, and sleep disorders. We report here a 3-year-old girl diagnosed with mosaic PTLS harboring a supernumerary marker chromosome containing the RAI1 (retinoic acid induced 1) gene. Cytogenetic testing, including chromosomal microarray, karyotype, and FISH analysis, identified a ring chromosome containing portions of chromosomes 14 and 17 in [...]

1181 6582

Open Access Case Report

A Child Carrying a Large Deletion in the 10p.15.3-p12.31 Region

Received: 01 June 2024;  Published: 20 August 2024;  doi: 10.21926/obm.genet.2403257

Abstract

Partial deletion of 10p is a rare disorder. Common features of this disorder include intellectual disability, developmental delay, dysmorphic features, hypoparathyroidism, deafness, and renal anomalies, but the phenotypes can vary between patients. We report an infant girl presented with global developmental delay, distinctive facial features with cleft lip, congenital exotropia, laryngomalacia, atrial septal defect, and sensorineural hearing loss. 46, XX, del (10p→ter) was observed on the G-banded analysis. A chro [...]

889 6565

Open Access Review

Potential Use of Human Mesenchymal Stem Cells (hMSCs) in Pancreatic Damage/Cancer

Received: 13 March 2024;  Published: 17 July 2024;  doi: 10.21926/obm.genet.2403252

Abstract

Pancreatic damage and pancreatic cancer pose significant challenges due to their complex pathogenesis, limited treatment options, and poor prognosis. In recent years, the potential use of human Mesenchymal Stem Cells (hMSCs) has been explored to address these complex pancreatic conditions and develop novel therapeutics. hMSCs, known for their regenerative and immunomodulatory properties, offer a novel therapeutic avenue for repairing damaged tissues and possibly inhibiting cancer progression. This communication dis [...]

955 6563

Open Access Research Article

Monitoring Energy-Loss-Driven-Cost by Using Earned Value Simulation in Complex Systems

Received: 24 July 2023;  Published: 06 February 2024;  doi: 10.21926/jept.2401004

Abstract

The economic impact of energy loss stemming from end-user electricity consumption is a significant concern, with historical trends revealing escalating costs. Effectively managing both peak and off-peak demands remains a formidable challenge due to the unpredictable nature of consumer behaviors, leading to energy wastage. This study delves into the nexus of demand uncertainty, financial repercussions, and potential strategies to mitigate energy losses in the evolving landscape of electricity consumption.that causes [...]

1125 6556

Open Access Original Research

Teachers Experiences in Mindfulness and Fitness Program: A Pilot Study

Received: 28 July 2023;  Published: 04 January 2024;  doi: 10.21926/obm.icm.2401002

Abstract

Current research shows that mindfulness and physical training programs have been shown to help reduce stress independently, however, limited research is available exploring the possible additive effects of implementing both training programs together [1, 2]. To test the feasibility and effectiveness of the Mind-Body Fitness program through a case-series pilot program, seven elementary school teachers completed a nine-week mindfulness and fitness program. The Perceived Stress Scale [3] was administered at three time [...]

981 6553

Open Access Research Article

Carbon Footprint Assessment Initiative and Trees Role in Reducing Emissions

Received: 08 October 2024;  Published: 23 January 2025;  doi: 10.21926/aeer.2501009

Abstract

Given the present emphasis on climate change and CO2 emissions, it is crucial to have specific guidelines to determine and mitigate carbon footprints. The following paper seeks to estimate the carbon emissions in kg of carbon dioxide equivalent from activities at Uniza Technical College and the tree's ability to absorb carbon dioxide through photosynthesis. The primary objective of this study is to determine how the emissions from campus trees can contribute to reducing overall carbon emissions. The methodologies e [...]

1088 6550

Open Access Review

Managing Acute Severe Necrotising Pancreatitis

Received: 25 February 2019;  Published: 05 June 2019;  doi: 10.21926/obm.hg.1902022

Abstract

Background: Severe necrotising pancreatitis (SNP) is characterised by high mortality, severe complications and bad prognosis despite progress in understanding of aetiology and progression of the disease. Traditionally, necrotic changes were removed by open necrosectomy but the paradigm has shifted towards more conservative management and minimally-invasive surgical procedures. However, there is still no consensus on the best management pathway. Minimally-invasive procedures percutaneous drainage, endoscopic transl [...]

1358 6540

Open Access Editorial

How Do Long Term Oral Pain Killers Enhance Pain and Promote Chronic Pain?

Received: 01 August 2022;  Published: 04 August 2022;  doi: 10.21926/obm.icm.2203032

Abstract

Oral pain medicines are routinely used to treat pain and chronic pain. Recent evidence shows that many of these medicines actually increase chronic pain when used over several weeks. Patients should be encouraged to find alternative pain treatments and avoid oral medicines for pain.

1156 6538

Open Access Original Research

Nutritional Counseling Improves the Nutritional Status, Liver Function, and Serum Electrolytes of Patients with Liver Transplantation

Received: 31 May 2023;  Published: 15 November 2023;  doi: 10.21926/obm.icm.2304051

Abstract

Nutrition counseling may assist liver transplant patients in controlling weight gain, addressing micronutrient deficiencies, and maintaining metabolic status. This study aimed to determine the effect of nutritional counseling on nutritional status, liver profile, and serum electrolytes of liver transplant patients. In this case-control study, 100 patients were recruited from Shifa International Hospital, Islamabad, who were potential liver transplant candidates. They were divided into two groups: a case group, who [...]

1223 6538

Open Access Review

Management of Steatosis in Living Donors: Where Do We Stand?

Received: 23 October 2023;  Published: 01 April 2024;  doi: 10.21926/obm.transplant.2402210

Abstract

With the progressive rise in rates of liver transplantation, stagnant donor pool, and social factors, living donor liver transplantation (LDLT) forms the majority of liver transplantations performed in Asian countries. As the global prevalence of metabolic-associated fatty liver disease (MAFLD) is increasing, around 17-25% of all the prospective donors turn out to be steatotic at the time of evaluation and, as such, rejected for donor hepatectomy, thereby considerably reducing the living donor pool. Steatotic graft [...]

964 6533

Open Access Research Article

The Relationship between Self-Compassion and Predictors of Depressed Mood in Parents of People with Eating Disorders

Received: 18 February 2023;  Published: 05 January 2024;  doi: 10.21926/obm.icm.2401004

Abstract

The aim of this study was to examine the relationships between self-compassion and possible predictors of depressed mood in parents of people with eating disorders. A questionnaire design was conducted cross‐sectionally in a sample of 112 parents of people with eating disorders. Participants completed measures of depressed mood, experiences of entrapment, shame, guilt, self-criticism and self-compassion. Regression analyses showed entrapment and self-criticism to be mediators between the relationship of shame and d [...]

1225 6521

Open Access Research Article

How Pathologists Dealt with the First Wave of the COVID-19 Pandemic: A Qualitative Study

Received: 14 July 2022;  Published: 14 December 2022;  doi: 10.21926/obm.neurobiol.2204148

Abstract

During the first wave of the COVID-19 pandemic, pathologists had to follow new protocols in their work environment around the world to limit or prevent the possibility of transmission of the infection during the autopsy of infected corpses. By using a qualitative research design, in this study, we investigated the emotions, experiences, and opinions of pathologists concerning changes in clinical practices. We specifically investigated their perspective on death. Our results encompassed five thematic areas, which in [...]

1098 6505

Open Access Original Research

Impact of Feeding Time and Duration on Body Mass and Composition in Young, Exercising Mice

Received: 21 December 2022;  Published: 22 August 2023;  doi: 10.21926/rpn.2303014

Abstract

Time-restricted feeding (TRF) has increased in popularity among various groups, including fitness enthusiasts. The ideal timing of TRF in relation to daily exercise is unknown. Most fitness enthusiasts consume meals immediately or soon after exercise to improve body composition (e.g., lean mass). We compared two different TRF approaches, as well as an ad libitum control diet, with regards to body mass and body composition in C57BL/6 mice. Young, healthy, male mice exercised five days per week and were assigned to c [...]

1040 6505

Open Access Editorial

Acknowledgement to Reviewers of OBM Genetics in 2021

Received: 05 January 2022;  Published: 06 January 2022;  doi: 10.21926/obm.genet.2201144

Abstract

The editors of OBM Genetics would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2021. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers receive a voucher entitling them to a discount on their next LIDSEN publication and can download a certificate of recognition direct [...]

1002 6500

Open Access Review

Exploring the Regenerative Potential of Stem Cells for Treating Eye Diseases: A Review of the New Findings

Received: 27 September 2023;  Published: 31 January 2024;  doi: 10.21926/obm.genet.2401212

Abstract

The escalating prevalence of vision loss due to eye diseases has instigated a quest for innovative therapies, given that conventional approaches often fall short in repairing and regenerating damaged eye tissues, particularly the retina. Stem cell-based interventions have emerged as a promising avenue, with numerous studies in animal models and human trials exploring their potential to enhance visual acuity. Beyond addressing conditions like age-related macular degeneration (AMD) and diabetic retinopathy (DR), stem [...]

1222 6497

Open Access Interview

An Interview with Dr. Masahiro Sato

Received: 13 December 2022;  Published: 14 December 2022;  doi: 10.21926/obm.genet.2204174

Abstract

An Interview with Dr. Masahiro Sato

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