by Gerasimos Rigatos  , Pierluigi Siano  , Mohammed AL-Numay  , Masoud Abbaszadeh  and Gennaro Cuccurullo

Received: 16 September 2023;  Published: 21 February 2024;  doi: 10.21926/jept.2401006

This article aims to treat the nonlinear control problem for the complex dynamics of a wave energy unit (WEC) that consists of a Permanent Magnet Linear Synchronous Generator (PMLSG) and a Voltage Source Converter (VSC). The article has developed a globally stable nonlinear optimal control method for this wave power generation unit. The new method avoids complicated state-space model transformations and minimizes the energy dispersion by the control loop. A novel nonlinear optimal control method is proposed for the [...]

by Fiona Bénard

Received: 15 June 2022;  Published: 16 November 2022;  doi: 10.21926/aeer.2204045

In the context of resource depletion and global warming, the energy transition has become a necessity. To provide a basis for analysis and to support countries in this transition, it is necessary to better understand this transition. The creation of a good measurement tool could help. This paper proposes a measure of national resilience through an analogy to kinetic energy. Preliminary results show that some countries have strong potential for resilience in the energy transition. Inequalities exist and still exist [...]

by Deepika Razia  , Ashraf Omar  , Katherine Grief  , Rajat Walia  and Sofya Tokman

Received: 20 November 2022;  Published: 01 March 2023;  doi: 10.21926/obm.transplant.2301176

Careful selection of lung transplant (LT) recipients with cystic fibrosis (CF) may improve outcomes; therefore, we studied the impact of sex and age at the time of LT on long-term survival of patients with CF. LT recipients with CF who received post-LT care at our center between July 1, 2007 and April 30, 2021 were included. The primary outcome was death or retransplantation. Cox proportional hazard analysis and the Kaplan-Meier method were used. Of 59 included LT recipients, the median age at first LT was 28 (22, [...]

by OBM Integrative and Complementary Medicine Editorial Office

Received: 02 April 2022;  Published: 18 April 2022;  doi: 10.21926/obm.icm.2202018

Interview with Dr. James David Adams. The skin is where pain is sensed and where chronic pain is created. The safest and most effective treatment for pain is topical plant medicines. Chronic pain can be cured with topical plant medicines. Transient receptor potential cation channels in the skin sense pain. Chronic pain involves a pain chemokine cycle. Monoterpenoids and diterpenoids from plants can stop this pain chemokine cycle and cure chronic pain.

by Vasiliy A. Chokheli  , Semyon D. Bakulin  , Olga Yu. Ermolaeva  , Vishnu D. Rajput  , Anatoly S. Azarov  , Arpna Kumari  , Victoriya V. Stepanenko  , Anastasia A. Bushkova  , Pavel A. Dmitriev  , Marcos Edel Martinez-Montero  and Tatiana V. Varduni

Received: 11 November 2022;  Published: 20 July 2023;  doi: 10.21926/obm.genet.2303187

Hedysarum cretaceum Fisch is a critically endangered herbaceous species with high ornamental and phytomeliorative properties; thus, it needs urgent conservation and protection methods to conserve. In the present study, an efficient method for microtonal propagation of H. cretaceum is developed. The seed sterilization was optimized as treatment with 96% alcohol (2 min) and burned (1 sec) through a burner flame. Murashige and Skoog (MS) medium with the addition of 0.5 mg/L 6-Benzylaminopurine (BAP) (shoots per explan [...]

by Babak Sokouti

Received: 30 October 2024;  Published: 14 March 2025;  doi: 10.21926/obm.neurobiol.2501276

Delirium is an acute neurocognitive disorder marked by disruptions in attention, cognition, and awareness, particularly prevalent among older and critically ill patients. This study applies a systems biology framework to dissect the molecular underpinnings of delirium and evaluate natural compounds for potential therapeutic roles. Through bioinformatics analyses, key biomarkers related to delirium, including IL6, AKT1, JUN, APP, and PPARGC1A, were identified, implicating pathways tied to neuroinflammation, oxidativ [...]

by Gohar Azhar  , Melodee Harris  , Laura Hays  , Patricia Savary  , Regina V. Gibson  , James R Perry  , Karen Coker  , Amanda Pangle  , Kenneth Alderson  and Jeanne Wei

Received: 08 January 2024;  Published: 06 March 2024;  doi: 10.21926/obm.geriatr.2401272

The COVID-19 pandemic caused abrupt changes in daily routines, social connections, and ways of life. It is yet unknown the full impacts these extended changes have had on the long-term mental well-being of those who shared this global experience. As a contribution to our overall understanding of this phenomena, this study explored the effects of the COVID-19 pandemic on the mental well-being of older adults in the Southern United States. Secondary data analyses were performed using the COVID-19 Emotional Impact Sur [...]

by Rim Werheni Ammeri  , Wafa Hassen  , Ines Mehri  , Nesrine Khelifi  and Abdennaceur Hassen

Received: 29 July 2022;  Published: 18 November 2022;  doi: 10.21926/rpm.2204024

Bioaugmentation by Pseudomonas strains is widely used for the removal of pollutants in wastewater. In this study, we aimed to determine the removal of pentachlorophenol (PCP, 800 mg·L–1) in secondary wastewater by the bioaugmentation process. We determined the effects of using three surfactants, namely sodium dodecyl sulfate (SDS), cetyl-tri-methyl-ammonium bromide (CTAB), and Tween 80 for PCP removal. We determined the effect of the role of PCP surfactant for the biofilm and auxin production of the se [...]

by OBM Neurobiology Editorial Office

Received: 05 January 2022;  Published: 06 January 2022;  doi: 10.21926/obm.neurobiol.2201114

The editors of OBM Neurobiology would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2021. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers receive a voucher entitling them to a discount on their next LIDSEN publication and can download a certificate of recognition di [...]

by Marco La Grua  , Gianfranco Sindaco  , Matteo Zanella  , Irene Grazzini  , Antonio Musio  , Alberto Merlini  , Valentina Paci  , Simone Vigneri  , Carmela Bertone  and Gilberto Pari

Received: 19 November 2022;  Published: 29 May 2023;  doi: 10.21926/obm.neurobiol.2302171

This study aims to determine if high-voltage PRF could effectively adjunct epidural adhesiolysis (EA) in treating patients with chronic lumbosacral radiating pain (LSRP) and neuropathic characteristics. A total of 409 patients suffering from a single leg-radiating pain lasting for > six months and unresponsive to previous treatments were divided into three different groups: Group 1 consisted of 227 patients suffering from LSRP in lumbar stenosis, 84 treated with EA alone and 143 with PRF-EA; group 2 consisted of [...]

by Subhranshu Sekhar Kar  , Rajani Dube  , Biji Thomas George  and Malay Jhancy

Received: 07 April 2024;  Published: 20 December 2024;  doi: 10.21926/obm.genet.2404276

There is a high prevalence of genetic abnormalities that significantly contribute to overall morbidity and mortality in neonates. Since early diagnosis is crucial for the optimal administration of conventional and customized medications, neonatal acute care has the most significant potential to benefit from genomic medicine. Genome sequencing has been demonstrated to have diagnostic, therapeutic and informational value in many investigations. With underlying genetic disorders, genome sequencing has the power to cha [...]

by Hannah O'Connor  , Joseph Biederman  , Maura DiSalvo  , Gagan Joshi  , Stephen V. Faraone  and Janet Wozniak

Received: 25 January 2024;  Published: 04 June 2024;  doi: 10.21926/obm.icm.2402031

The aim of this paper is to examine effects of stimulant treatment in children and adolescents with high levels of emotional dysregulation in a psychiatric outpatient clinic. Subjects were referred children and adolescents 6-17 years of age who presented to a child psychiatric outpatient clinic between September 2016-November 2021 and received a prescription for a stimulant medication. Children were stratified into those with low and high levels of emotional dysregulation as defined by an aggregate T-score of <1 [...]

by Melissa L. Harris-Gersten  , Florence U. Johnson  , Josephine R. Granner  and Susan N. Hastings

Received: 20 June 2023;  Published: 10 August 2023;  doi: 10.21926/obm.neurobiol.2303178

People diagnosed with dementia are experts on living with the disease, yet their perspectives are often overlooked in research and practice. The pandemic has amplified health inequities among older adults, but the impact of the pandemic on the lived experience of people living with dementia remains unclear. This qualitative study used a series of 2 virtual focus groups with people living with dementia (N = 7) to explore challenging situations and emotions experienced by community-dwelling people living with dementi [...]

by Gabriel de Souza Vieira Bié  , Zilda de Castro Silveira  , Rafael Vidal Aroca  and Marcia Cristina Branciforti

Received: 07 February 2025;  Published: 28 May 2025;  doi: 10.21926/rpm.2502010

Tissue engineering is a technique for regenerating living tissue using portions of the patient's tissue, which are dissociated into cells and cultured on biological or synthetic supports before being transferred to the patient. In this context, the present study seeks to develop implant models (scaffolds) for replacing trabecular bone tissue, with requirements such as porosity and interconnected pores. All design development was aimed at the manufacturing of scaffolds using the material extrusion additive manufactu [...]

by Adriano Zamperini  , Antonella Pittella  , Cristina Rizzo  , Giulia Marangon  , Erika Iacona  and Ines Testoni

Received: 24 July 2022;  Published: 10 March 2023;  doi: 10.21926/obm.neurobiol.2301162

The COVID-19 pandemic has drastically changed our daily lives. One of the sectors most affected was tourism and travel – and, more specifically, cruises, given the prolonged time passengers spend with others within the small spaces of the cruise ship. While finding well-organised entertainment opportunities on cruises is possible, emergency conditions may cause panic. On such occasions, reactions can be highly stressful or even traumatic. This research explores the events and emotions experienced by passengers duri [...]

by Domingo J. Franco-Palacios  , Lisa Allenspach  , Lisa Stagner  , Kelly Bryce  , Jane Simanovski  and Hassan Nemeh

Received: 01 May 2023;  Published: 17 July 2023;  doi: 10.21926/obm.transplant.2303193

In the United States of America, COVID-19 acute respiratory distress syndrome (ARDS) and post-COVID pulmonary fibrosis (PCPF) are raising indications for lung transplant (LT). Another indication for LT is underlying fibrosis with SARS-CoV-2 induced interstitial lung disease exacerbation or rapid progressing fibrosis. Only a few centers have reported on their long-term outcomes after LT for COVID-19. Single center retrospective chart review of patients transplanted for COVID-19 related lung disease. The Henry Ford H [...]

by Samantha Varley  , Kirsten Rossi  , Meghan Murray  and Alissa Nichole

Received: 17 May 2019;  Published: 12 July 2019;  doi: 10.21926/obm.hg.1903026

Acute pancreatitis (AP) is an inflammatory condition of the pancreas and is one of the most common ailments of the gastrointestinal system that results in significant morbidity and mortality. The main etiologic causes of AP are alcohol consumption, gallstones, hypertriglyceridemia, and biliary stones. The clinical signs and symptoms, and diagnostic criteria of AP are well established in the literature and multiple studies. Multiple scoring systems have been used to predict the severity, prognosis, and mortality a [...]

by Shechter Yonat  , Dagan Amir  , Ben-Haim Menachem  , Bar-Ziv Yaakov  , Brazovsky Eliyau  , Shteingart Shimon  , Dancour Alian  , Paz Kalman  and Lurie Yoav

Received: 17 February 2018;  Published: 01 September 2018;  doi: 10.21926/obm.hg.1803009

Cholangiocarcinoma is an uncommon adenocarcinoma with poor prognosis. Signet ring cell cholangiocarcinoma is an extremely rare disease, with only 11 cases reported to date. However, its incidence is increasing. Similarly, there is an increasing incidence of other SRC tumors (colon, gastric etc.) as well. Most cases have described a localized mass of signet ring cells, mostly in the common bile duct. A 69-year-old Caucasian man admitted for jaundice and abdominal pain that began 3 days prior to his hospitalization. [...]

by Ramareddy V Guntaka

Received: 20 December 2018;  Published: 13 March 2019;  doi: 10.21926/obm.hg.1901014

Liver fibrosis leading to cirrhosis and cancer affects millions of people and causes thousands of deaths all over the world. Many signaling pathways could be targeted to block fibrosis but these are not successful. Reviewing recent literature and from our own studies we identified novel target, such as YB-1, which is implicated in inflammation, angiogenesis and accumulation of extracellular matrix (ECM). In addition we observed and showed that the end product of fibrosis, collagen gene, itself is a direct target fo [...]

by Joep Geraedts

Received: 16 January 2017;  Published: 10 February 2017;  doi: 10.21926/obm.genet.1701001

by Tommy Sundqvist  , Lars Stenhammar  , Bo Tjellström  , Karl-Eric Magnusson  , Tore Midtvedt  , Elisabeth Norin  and Lotta Högberg

Received: 07 February 2020;  Published: 09 March 2020;  doi: 10.21926/obm.hg.2001043

by Sergey Yu. Udovichenko  , Alexander D. Pisarev  , Alexander N. Busygin  , Abdulla H. Ebrahim  , Andrey N. Bobylev  and Alexey A. Gubin

Received: 14 June 2022;  Published: 22 September 2022;  doi: 10.21926/obm.neurobiol.2203134

In the present study, we present the results of the modeling of incoming information processing in a neuroprocessor that implements a biomorphic spiking neural network with numerous neurons and trainable synaptic connections between them. Physico-mathematical models of processes of encoding information into biomorphic pulses and their decoding following a neural block into a binary code were developed as well as models of the process of routing the output pulses of neurons by the logic matrix to the synapses of oth [...]

by OBM Transplantation Editorial Office

Received: 01 July 2022;  Published: 03 July 2022;  doi: 10.21926/obm.transplant.2203161

by Nani Maharani  , Agustini Utari  , Nydia Rena Benita Sihombing  and Tri Indah Winarni

Received: 01 June 2024;  Published: 20 August 2024;  doi: 10.21926/obm.genet.2403257

Partial deletion of 10p is a rare disorder. Common features of this disorder include intellectual disability, developmental delay, dysmorphic features, hypoparathyroidism, deafness, and renal anomalies, but the phenotypes can vary between patients. We report an infant girl presented with global developmental delay, distinctive facial features with cleft lip, congenital exotropia, laryngomalacia, atrial septal defect, and sensorineural hearing loss. 46, XX, del (10p→ter) was observed on the G-banded analysis. A chro [...]

by Tomomi Kogiso  , Mutsuki Kobayashi  , Kuniko Yamamoto  , Yuichi Ikarashi  , Kazuhisa Kodama  , Makiko Taniai  , Nobuyuki Torii  , Kazunari Tanabe  , Hideki Ishida  , Shohei Fuchinoue  , Hiroto Egawa  , Masakazu Yamamoto  , Etsuko Hashimoto  and Katsutoshi Tokushige

Received: 08 February 2017;  Published: 06 April 2017;  doi: 10.21926/obm.hg.1702003

Background: Hepatitis C virus (HCV) infection frequently occurs in recipients of liver or kidney transplants (LT/KT). Interferon (IFN)-based therapies are used to treat HCV, but their efficacy is low. Methods: We report 24 patients who received HCV therapy after LT/KT. Design, Setting, and Participants-Twelve LT and 12 KT recipients (median age, 59 years; 15 males; 21 serological type 1) were enrolled, of whom eight (six with LT) were treated with IFN-based therapy. Twelve received direct-acting antiviral drugs [ [...]