Table of Contents

Open Access

ISSN 2573-4407

OBM Neurobiology , Volume 8 , Issue 1 (2024)

Pages: 200

Published: April 2024

(This book is a printed edition that was published in OBM Neurobiology )

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Format: Soft Cover


Cover story:The study adapted a new interactive technology system to help six participants with intellectual and other disabilities exercise relevant physical responses (stretching arms and shoulders laterally or high up forward) to place objects in a container located to their left, to their right, or high up in front of them.View this paper.

Volume 8,Issue 1

Open Access Short Review

Postoperative Cognitive Dysfunction and Virtual Reality for Cognitive Rehabilitation in Cardiac Surgery Patients: A Short Review

Received: 02 November 2023;  Published: 19 March 2024;  doi: 10.21926/obm.neurobiol.2401215


Postoperative cognitive dysfunction (POCD) has been observed as a complication after cardiac surgery consistently. The ineffectiveness of current treatments for POCD is causing a search for non-invasive alternatives. The present review aims to consolidate the current understanding of how VR methods effectively facilitate the recovery of cognitive functioning in cardiac surgery patients. To obtain information about the effects of VR technology on cognitive functions, we investigated the PubMed, S [...]

Open Access Case Report

Management of Posttraumatic Cerebrospinal Fluid Leak with Secondary Diffuse Pneumocephalus Complicated by Meningitis and Communicating Hydrocephalus – Illustrative Case Report

Received: 10 January 2024;  Published: 13 March 2024;  doi: 10.21926/obm.neurobiol.2401214


Rhinorrhea is a possible complication after different types of traumatic brain injury or neurosurgical procedures, such as skull base operations. Pneumocephalus is a rarely noted complication after severe traumatic brain injury, and it may be accompanied by meningitis and ventriculitis, especially when treatment has been delayed. Treatment of these entities includes conservative and surgical approaches. Pneumocephalus may result in neurologic disturbances threatening a life. Therefore, active pa [...]

Open Access Correction

Correction: Tse et al. How COVID-19 Ceases All Older Adult Services & the Way Out for Community-Dwelling Older Adults with Chronic Pain. OBM Neurobiology 2023; 7: 183

Received: 11 March 2024;  Published: 12 March 2024;  doi: 10.21926/obm.neurobiol.2401213


CorrectionCorrection: Tse et al. How COVID-19 Ceases All Older Adult Services & the Way Out for Community-Dwelling Older Adults with Chronic Pain. OBM Neurobiology 2023; 7: 183Mimi Mun Yee Tse 1, *, Shamay Sheung Mei Ng 2, Vivian Lou 3, Raymond SK Lo 4, Daphne Sze Ki Cheung 5, Paul [...]

Open Access Original Research

Resilience in Adversity: COVID-19 Pandemic Challenges in Diminishing Entrepreneurial Intentions and Business Startups

Received: 13 November 2023;  Published: 11 March 2024;  doi: 10.21926/obm.neurobiol.2401212


In this study, the researchers explore the effects of COVID-19-related challenges, such as fear and anxiety about COVID-19, the uncertainty of COVID-19, and the recognition of business opportunities for entrepreneurial intentions and business startups. This study used quantitative methods and based their findings on 278 usable samples collected from Egyptian entrepreneurs. Employing the Structural Equation Model (SEM) through SmartPLS4 shows that fear and anxiety arising from the COV [...]

Open Access Review

The Role of Cognition in Balance Control

Received: 14 September 2023;  Published: 17 February 2024;  doi: 10.21926/obm.neurobiol.2401211


Balance is the ability to move and/or preserve a particular position while not falling under external force. Human balance is a complex process of integration and coordination of the sensory, motor, and biomechanical components, which is influenced by intrinsic and exogenous factors. One inherent factor that is hypothesized to have an impact on balance is cognition. However, studies about cognition's role in balance control are still limited, and study literature is needed to gain a better under [...]

Open Access Editorial

Pain and Neurobiology

Received: 01 February 2024;  Published: 02 February 2024;  doi: 10.21926/obm.neurobiol.2401210


Neurobiology is an expansive field of studies encompassing the nervous system's anatomical and physiological aspects [1]. This complex framework's deep study and understanding have facilitated a more intricate comprehension of the interconnections among various nervous system components implicated in pain perception, transmission, modulation, and adaptation.

Open Access Review

The Association between Uric Acid Level and Ischemic Stroke

Received: 11 July 2023;  Published: 16 January 2024;  doi: 10.21926/obm.neurobiol.2401209


Stroke is the second and third leading cause of death and disability, respectively, all over the world. It seriously affects patients' lives and brings huge burdens to their families. Ischemic stroke accounts for most of the stroke cases. In the absence of any effective treatment, prevention measures through controlling the risk factors for ischemic stroke become crucial. While uric acid has been reported as an essential risk factor for ischemic stroke, researchers hold inconsistent views regard [...]

Open Access Review

Scope of Nanomaterials in Treating Neurological Disorders

Received: 08 November 2023;  Published: 11 January 2024;  doi: 10.21926/obm.neurobiol.2401208


In the last decade, development in nanotechnology has been used intensively. By studying nanotechnology and nanomaterials, we can generate excellent responses in healthcare related to neurological disorders. It also includes easy diagnosis of diseases in their early stages, delivery of genes, and many more. Neurological disorders are one of the most sensitive topics. Therefore, nanomaterials promise to treat neurological disorders as they are highly efficient. Nanomaterials will significantly ex [...]

Open Access Original Research

Neuroprotective Effects and Cognitive Enhancement of Allomargaritarine in 5xFAD Alzheimer's Disease Mice Model

Received: 23 August 2023;  Published: 09 January 2024;  doi: 10.21926/obm.neurobiol.2401207


Here, we report the results of an investigation of the neuroprotective effects of securinine with tryptamine conjugate-allomargaritarine (2b), previously selected as the leading compound among a wide range of natural derivatives. 2b was synthesized from securinine using various Lewis acids as catalysts. In addition to the antioxidant and cytoprotective properties previously shown for 2b, in this work, in vitro analysis of the biological activity of the compound demonstrated [...]

Open Access Original Research

Patient-Reported Outcome Measures (PROMs) in Neurology for Web 3.0 and mHealth: A Conceptual Framework

Received: 02 June 2023;  Published: 09 January 2024;  doi: 10.21926/obm.neurobiol.2401206


According to 2019 WHO data, neurological conditions contribute to 1503.39 disability-adjusted life years (DALYs) per 100,000 population. Approximately 57% of office-based physicians use EHR systems and the natural place to incorporate standardized ePRO is into EHR. However, implementing patient-reported outcomes (PROs) for neurological conditions is challenging because many patients are elderly, have comorbidities, and experience cognitive impairment. As healthcare digitization increases, we pro [...]

Open Access Original Research

The Impact of Psychological Stress on Personal Income, Physical Health and Entrepreneurial Intentions among Entrepreneurs

Received: 19 September 2023;  Published: 04 January 2024;  doi: 10.21926/obm.neurobiol.2401205


Entrepreneurial intention plays a pivotal role within entrepreneurship ecosystems, acting as a catalyst for economic growth and innovation by inspiring individuals to embrace entrepreneurship as a viable career pursuit. The present research delves into the intricate dynamics between stress, entrepreneurial intention, personal income, and physical health within Egypt's entrepreneurial landscape. Grounded in a quantitative analysis of 286 valid samples and utilizing SmartPLS 4, this study unveils [...]

Open Access Editorial

Acknowledgement to Reviewers of OBM Neurobiology in 2023

Received: 03 January 2024;  Published: 04 January 2024;  doi: 10.21926/obm.neurobiol.2401204


The editors of OBM Neurobiology would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2023. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal’s editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers receive a voucher entitling them to a discount on their next LIDSEN publica [...]

Open Access Original Research

Interactive Technology to Help People with Multiple Disabilities Practice Relevant Physical Responses within an Occupational Task

Received: 09 October 2023;  Published: 02 January 2024;  doi: 10.21926/obm.neurobiol.2401203


This study adapted a new interactive technology system to help six participants with intellectual disability and visual and motor impairments to exercise relevant physical responses as part of an occupational task. The task was to place objects into different containers from a sitting position. The responses, which changed across sessions, consisted of the participants (a) stretching the left arm and shoulder to place objects in a container located to their left, (b) stretching the right arm and [...]