Register or Submit a manuscript.
Table of Content

Open Access Short Communication

Efficacy of a Plant-based Diet (Semi-lacto-ovo-vegetarian Diet) for Treating Constipation

Received: 23 December 2021;  Published: 02 April 2022;  doi: 10.21926/rpn.2202012

Abstract

A modern lifestyle, including dietary westernization, has increased the prevalence of constipation. The authors developed a plant-based diet for inflammatory bowel disease. This study investigated whether a diet containing a high amount of dietary fiber is also effective for constipation. Consecutive patients with constipation were recruited in this study from April 2003 to March 2004. Their constipation was unresponsive to a conventional laxative. The patients were provided a plant-based diet during hospitalizatio [...]

1560 115288

Open Access Perspective

Nutrition for Healing Acute and Chronic Wounds: Current Practice, Recent Research Findings, and Insights for Improving Care

Received: 20 March 2024;  Published: 10 September 2024;  doi: 10.21926/rpn.2403014

Abstract

Wound prevalence is increasing as the global population ages. Older adults are at risk of wounds from falling and from other medical conditions that contribute to wound development and slowed healing (e.g., diabetes, cancer, chronic infections); they often experience health conditions that necessitate surgery and therefore post-surgical healing. Poor nutrition status, which includes deficiencies in macro- and micronutrients, is recognized as a key contributor to impaired wound healing in older adults. As such, the [...]

2692 48692

Open Access Review

Sunflower Seeds (Helianthus Annuus) and Health Benefits: A Review

Received: 29 October 2022;  Published: 06 July 2023;  doi: 10.21926/rpn.2303010

Abstract

A literature review was conducted to present an overview of sunflower seeds, nutritional value, and health benefits. Sunflower seeds are inexpensive, readily available, and nutritious all year long. Some of the most important nutrients for humans are found in them in particularly high concentrations. There are several vitamins in sunflower seeds, including vitamin B1 and B5, vitamin E and folate. Additionally, they contain important minerals like copper, magnesium, selenium, and phosphorous. The fats in sunflower s [...]

3596 46063

Open Access Short Review

Simiao Powder as an Effective Remedy for Gout

Received: 29 November 2023;  Published: 11 May 2024;  doi: 10.21926/rpn.2402009

Abstract

Gout is an increasing metabolic disease due to the buildup of uric acid. The buildup of uric acid due to inadequate excretion leads to uric acid crystal formation. Treatment for gout aims to eliminate the uric acid crystal formation so that inflammation decreases. Traditional gout medication is usually allopurinol, but increasing studies have proven that herbal remedies may be promising. Over the past few years, studies have demonstrated that Simiao powder, a traditional Chinese medicine (TCM), is more effective th [...]

2448 39347

Open Access Review

The Effects of Creatine Supplementation on Markers of Muscle Damage and Inflammation Following Exercise in Older Adults: A Brief Narrative Review

Received: 04 July 2022;  Published: 12 October 2022;  doi: 10.21926/rpn.2204021

Abstract

Exercise induced muscle damage occurs following strenuous and unfamiliar exercise and results in biomarkers of muscle damage and inflammation in the circulation. Creatine (Cr) is a commonly utilized nutritional supplement which has been proposed to enhance post-exercise recovery and has been suggested to decrease exercise induced inflammation. Exercise is well recognized to be beneficial for older adults to maintain skeletal muscle mass and strength as well as promote health for other biological systems. However, o [...]

2282 29594

Open Access Review

Ketogenic Therapy for Major Depressive Disorder: A Review of Neurobiological Evidence

Received: 06 December 2021;  Published: 17 February 2022;  doi: 10.21926/rpn.2201003

Abstract

Major depressive disorder (MDD) is a debilitating illness that places a great burden on global health. A ketogenic diet, which has traditionally been used for treating refractory epileptic disorders, is being increasingly explored for its potential of alleviating other neuropsychiatric conditions. Providing an up-to-date summary on the ketogenic diet’s potential to alleviate MDD, its neurobiological basis, and preliminary clinical evidence. A structured literature survey was performed, and a narrative review was wr [...]

1928 25004

Open Access Original Research

The Impact of Breakfast Omission on Daily Activities and Academic Achievement: A Cross-Sectional Study at Fazaia Ruth Pfau Medical College

Received: 04 April 2024;  Published: 27 September 2024;  doi: 10.21926/rpn.2403016

Abstract

Breakfast omission can essentially impact daily activities and academic performance, leading to diminished energy, poor concentration, mood disturbances, and potentially lower academic accomplishment. Advancing the significance of a nutritious breakfast and ensuring access to such meals is crucial for physical and cognitive prosperity. Examine the effect of breakfast exclusion on daily activities and insightful achievement in specific people. This study intends to evaluate the potential significance of findings in [...]

5091 24650

Open Access Review

Sulforaphane: The Principal Broccoli Phytochemical as a Cancer Challenger

Received: 10 January 2022;  Published: 14 March 2022;  doi: 10.21926/rpn.2201008

Abstract

Broccoli has long been reported to exert a positive impact on human health. It contains high levels of isocyanates, the most important of which is sulforaphane (SFN). Numerous studies have demonstrated that SFN can be used as an effective supplement for treating a variety of diseases. In addition, it is known to possess anti-cancer properties such as chemopreventive properties against gastrointestinal, breast, lung, bladder, prostate, and other cancers. The reported data indicates that broccoli could be a potent in [...]

1692 24102

Open Access Research Article

Microwave-Assisted Extraction of Phenolic Compounds from Broccoli (Brassica oleracea) Stems, Leaves, and Florets: Optimization, Characterization, and Comparison with Maceration Extraction

Received: 17 February 2022;  Published: 01 April 2022;  doi: 10.21926/rpn.2202011

Abstract

Microwave-assisted extraction (MAE) to obtain phenolics from vegetable wastes has been of recent interest. Broccoli is one of the most globally produced vegetables, and around 43% of the harvest is considered waste. Thus, given the significant quantity of broccoli waste generated, the objective of this work was to optimize the MAE, to maximize the total phenolic content (TPC) from broccoli by-products (leaves and stems) and broccoli florets. The Response Surface Analysis was used in the optimization model to evalua [...]

2405 23000

Open Access Perspective

Therapeutic Carbohydrate Reduction for Lipedema: Guidelines for a Patient-Centered, Holistic Approach

Received: 31 May 2025;  Published: 03 September 2025;  doi: 10.21926/rpn.2503019

Abstract

Lipedema is a chronic, often misdiagnosed disease characterized by painful, disproportionate fat accumulation in the extremities. Commonly mistaken for obesity or lymphedema, lipedema primarily affects women and has long been thought to be resistant to dietary intervention, a belief originating from its initial description by Allen and Hines at the Mayo Clinic in 1940. However, emerging research challenges this notion, revealing that individuals with lipedema often respond positively to therapeutic carbohydrate (CH [...]

2044 20459

Open Access Original Research

Increasing the Omega-3 Index of Endurance Trained Adults: A Pilot Study Comparing Microencapsulated Algae to Fish Powders Provided as Chewable Tablets

Received: 12 November 2024;  Published: 19 March 2025;  doi: 10.21926/rpn.2501004

Abstract

Long-chain omega-3 fatty acids (LCn-3PUFA), including eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), support heart function during exercise and recovery by incorporating into the cardiac cell membranes. Traditionally sourced from fish and fish oil, algae-derived LCn-3PUFA have become alternative in supplemental forms. This study evaluated whether 12 weeks supplementation of a microencapsulated algal oil, delivered as chewable tablets, would perform equivalently to fish-derived LCn-3PUFA in boosting the [...]

1094 19533

Open Access Short Review

Effects of Natural Substances on Lowering Uric Acid

Received: 03 March 2023;  Published: 28 September 2023;  doi: 10.21926/rpn.2303019

Abstract

Uric acid (UA) metabolism, which includes uric acid production controlled by purine metabolism and uric acid excretion controlled by the gastrointestinal tract and kidneys, is the primary way to maintain the concentration of uric acid in the body. Abnormal functionalizing of the metabolism may cause hyperuricemia, gout, kidney injury, and other diseases. Over the last decade, numerous studies have been conducted on the effect of natural products, including active ingredients of medicinal plants, natural compounds, [...]

3701 17014

Open Access Original Research

The Effects of Supplemental Vitamin C in Mandibular Fracture Patients: A Randomized Clinical Trial

Received: 23 June 2023;  Published: 21 November 2023;  doi: 10.21926/rpn.2304021

Abstract

Vitamin C is an oxidative stress mediator and essential cofactor in wound healing. The objective of this study was to investigate the clinical and biochemical effects of vitamin C supplementation on outcomes in patients undergoing mandibular fracture repair. We also aimed to evaluate the effects of sociodemographic, fracture, and treatment characteristics on post-operative clinical outcomes in these patients. The investigators conducted a double-blind, placebo-controlled, randomized clinical trial at Two Metropolit [...]

2377 15774

Open Access Original Research

Consumption of a Recommended Serving of Wheat Bran Cereals Significantly Increases Human Faecal Butyrate Levels in Healthy Volunteers and Reduces Markers of Inflammation Ex Vivo

Received: 08 October 2021;  Published: 17 December 2021;  doi: 10.21926/rpn.2104002

Abstract

Wheat bran cereals are an important source of dietary fibre. The aim of the study was to investigate if a high intake (120 g) of fibre rich breakfast cereal (which delivers the UK Government guidelines for fibre intake in one serving but is three-fold higher than the manufacturers recommended serving) has additional potential health benefits compared to the recommended serving (40 g, containing 11 g of dietary fibre). To assess this, the study determined the short chain fatty acid (SCFA) profiles in human faecal, u [...]

1981 15729

Open Access Review

Curiosities of Weight Loss Diets of the Last 60 Years

Received: 07 September 2023;  Published: 23 November 2023;  doi: 10.21926/rpn.2304022

Abstract

Lately, we've witnessed the emergence of obesity as a prominent concern for public health and the economy. This issue commands serious attention, impacting millions worldwide, particularly in the most developed nations. Practical approaches to tackling obesity involve tailored physical activity and dietary interventions overseen by qualified healthcare professionals. Nonetheless, some individuals opt for quicker routes, embracing dietary regimens that promise rapid and effortless weight reduction yet lack substanti [...]

1513 15689

Open Access Review

Exclusive Enteral Nutrition as an Effective Treatment in Inflammatory Bowel Disease

Received: 17 November 2024;  Published: 13 May 2025;  doi: 10.21926/rpn.2502010

Abstract

In recent years, the incidence of Inflammatory Bowel Disease (IBD) has risen significantly in the Western population, pointing toward the potential influence of environmental and dietary factors. In order to explain this, some research on nutritional therapy identifies exclusive enteral nutrition (EEN) as a highly effective approach for managing IBD in children. This treatment achieves high remission rates; more specifically, some clinical trials have reported remission rates from 70% to 100%. EEN not only facilita [...]

827 15306

Open Access Review

Dietary Modulation of the Gut Microbiome in Inflammatory Bowel Disease

Received: 28 April 2022;  Published: 09 August 2022;  doi: 10.21926/rpn.2203019

Abstract

Inflammatory bowel disease (IBD), which includes ulcerative colitis, and Crohn’s disease, is a chronic relapsing-remitting inflammatory state of the gastrointestinal (GI) system. The cause of IBD is multifactorial, encompassing factors of genetics, environment, and the host immune system, initiating a complex interplay of maladaptive host immune responses and subsequent chronic inflammation. Aberrant host immune responses are at least in part due to changes in the commensal microbiome, which can in turn affect the [...]

1297 14484

Open Access Case Report

Translating Evidence into Practice: A Case Study of Extended Use of a Very Low Energy Diet for Treatment of Co-Morbid Obesity and Chronic Disease

Received: 21 February 2022;  Published: 27 May 2022;  doi: 10.21926/rpn.2202015

Abstract

We report the case of a 30-year-old male with significant obesity (body mass index 47 kg/m2) with co-existing moderate obstructive sleep apnoea, hypertension, hypercholesteremia and hypogonadotropic hypogonadism, who was treated with a very-low-energy diet (VLED) and lifestyle modification programme for 12 months. The patient lost weight throughout the entire treatment period (average weight loss was 2.1 kg/week, for a total of 42.7 kg), and showed marked improvement in co-morbidities and no adverse effects. This c [...]

1561 14313

Open Access Review

Role of Diet in the Pathogenesis of Colorectal Polyps and Cancer

Received: 24 April 2022;  Published: 01 August 2022;  doi: 10.21926/rpn.2203018

Abstract

Colorectal cancer (CRC) is currently the third most common cancer within the United States among both males and females, with increasing rates occurring in younger individuals compared to the past. Multiple environmental and social aspects including diet may be contributing to this increase in CRC rates. The aim of this review is to examine foods containing high fructose corn syrup, processed meats, and red meats which have shown to be linked to an increase in incidence of CRC. These foods can be a cause for disrup [...]

1791 14094

Open Access Original Research

Physical Activity Mentoring in Schools: An Undergraduate-Mentored Running Intervention for Elementary Students

Received: 17 December 2021;  Published: 15 March 2022;  doi: 10.21926/rpn.2201009

Abstract

Most children do not meet physical activity guidelines, and school-based programs often fail to increase physical activity levels. However, there has been no intervention pairing college mentors with elementary students to date. The purpose of this paper is to report the feasibility and acceptability, both quantitative and qualitative, of an undergraduate-mentored running program designed to increase physical activity in elementary students. A convergent parallel mixed methods design was used to evaluate the feasib [...]

1580 14093

Open Access Research Article

An Exploration of Preschool Teachers’ Perceptions of Physical Activity Integration in a Whole Child Pilot Curriculum

Received: 15 November 2021;  Published: 13 January 2022;  doi: 10.21926/rpn.2201001

Abstract

It is recommended that children ages 3-5 receive 180 minutes of physical activity a day, with at least 60 minutes of moderate-to-vigorous physical activity. Despite these recommendations, a majority of preschoolers are not provided opportunities in the early childhood education setting to meet these daily recommendations through either structured or unstructured physical activity. Accordingly, the number of young children identified as overweight or obese over the past couple of decades has increased. Critical to a [...]

1991 14085

Open Access Review

Role of Nutrition in the Management of Inflammatory Bowel Disease

Received: 21 June 2024;  Published: 10 January 2025;  doi: 10.21926/rpn.2501002

Abstract

The persistent inflammation of the intestinal mucosa is the main characteristic of inflammatory bowel disease (IBD), a lifelong illness that affects people of both genders. The exact etiology is still undefined while previously it was attributed to genetic components. Later, it was investigated that the environment has an equal effect on the development of IBD encompassing both Crohn’s disease (CD) and Ulcerative colitis (UC). Among environmental risk factors linked to IBD, diet, notably the transition toward the W [...]

1425 13997

Open Access Research Article

Chair Fitness Program for Improved Strength and Physical Function for Older Adults: A Pilot Comparative Effectiveness Study

Received: 05 July 2023;  Published: 12 September 2023;  doi: 10.21926/rpn.2303016

Abstract

Within the US, people are experiencing longer life expectancy, yet these extended lifespans have not necessarily translated into years living in good health. Musculoskeletal degenerative diseases are particularly prevalent amongst older adults. Research shows that regular resistance exercise carries preventive health benefits to combat these conditions. This study evaluated the impact of an innovative hand-held device (OYO) on the physical function of older adults compared to a traditional chair fitness program (CF [...]

1185 13448

Open Access Review

Ellagic Acid - A Dietary Polyphenol with Anticancer Activity that Deserves More Consideration

Received: 21 March 2023;  Published: 13 July 2023;  doi: 10.21926/rpn.2303011

Abstract

Ellagic acid (EA) the principal polyphenol of pomegranate (Punicca granatum) is renowned for its beneficial therapeutic activity in several diseases including cancer. Studies have shown that EA exerts a carcinopreventive effect on many cancer cells, inducing cell cycle arrest and apoptosis, and limiting neovascularization and cell migration. In animal models, EA could reduce tumor development, number and size. Research detected that EA exerts its activity on cancer cells through several signaling pathways, without [...]

1431 12822

Open Access Review

Parenteral Nutrition: Review of Recent American Society for Parenteral and Enteral Nutrition Publications

Received: 30 December 2021;  Published: 15 February 2022;  doi: 10.21926/rpn.2201002

Abstract

Parenteral nutrition (PN) is a complex medication administered to adult, pediatric, and neonatal patients. PN is recognized as a high-alert medication by the Institute for Safe Medication Practices (ISMP). The American Society for Parenteral and Enteral Nutrition (ASPEN) has published several key recommendations regarding safe use of PN. This manuscript will review several of the important PN papers published in 2020-2021 by ASPEN.

2000 12762

Open Access Research Article

Biochemical Impact of Carica Papaya (Pawpaw) leaves Extract and Ruzu Bitters on Hematology and Brain Histology in Sprague Dawley Rats

Received: 12 June 2022;  Published: 02 March 2023;  doi: 10.21926/rpn.2301004

Abstract

Plant-based products have been utilized for nutritional and medicinal purposes for decades. Although the reported benefits of Carica papaya (Pawpaw) leave extract, its role in hematology, brain histology, and the possible side effect are still areas of research deliberation. Thirty (30) male Sprague Dawley rats, divided into three groups, were fed on rat chow and normal saline, Carica papaya leaves extract and Ruzu bitters, respectively. Blood chemistry, hematology, and brain histology were assayed to ascertain the [...]

1380 12709

Open Access Original Research

Metabolic, Anthropometric and Blood Pressure Effects of Adding Two Kiwifruit or Bottled Water into the Diets of People with Pre-Diabetes: A Randomised, Parallel Group, Intervention Study

Received: 22 December 2021;  Published: 25 February 2022;  doi: 10.21926/rpn.2201006

Abstract

People with pre-diabetes may be reluctant to add fruit to their diets due to concerns around sugars. Our objective was to measure outcomes associated with potential adverse effects of ingesting fruit sugars while assessing metabolic benefits from eating nutrient-rich kiwifruit. Thirty-four people with pre-diabetes were randomized to receive two kiwifruit or 250 mL bottled water per day for 12-weeks; two people withdrew. The primary outcomes were between-group differences for glycated haemoglobin (HbA1c) and plasma [...]

1395 12449

Open Access Review

Senescence and DNA Damage in Adipocytes and Fat Tissues and Its Potential Amelioration through Nutritional Interventions

Received: 13 April 2022;  Published: 05 July 2022;  doi: 10.21926/rpn.2203016

Abstract

Accumulating evidence demonstrates that senescence and the associated inflammatory phenotype (SASP) also occur in post-mitotic cells such as mature adipocytes. Visceral adipose tissue in humans is susceptible to inflammation due to nutritional imbalance and ageing. However, while adipose tissue has been well researched in the context of obesity, senescence of differentiated adipocytes has not been investigated thoroughly. Our group recently demonstrated that ageing and normal ad libitum (AL) nutrition in mice resul [...]

1433 12428

Open Access Review

Dietary Needs, Approaches and Recommendations to Meet the Demands of Future Manned Space Flights

Received: 09 December 2021;  Published: 23 February 2022;  doi: 10.21926/rpn.2201005

Abstract

Space flight imposes a myriad of adverse effects upon the human body. Improved in-flight nutritional strategies help mitigate those adverse effects. This review examines how space flight changes human physiology, and how improved in-flight nutritional strategies may address the unique dietary needs created by microgravity exposure. Dietary approaches and recommendations to address those needs are discussed. This review also describes food sustainability methods for long-term manned space flight, how precision nutri [...]

1431 12392

Open Access Research Article

Postprandial Glucose Responses to Standardised Meals Consumed After Moderate- and High-Intensity Exercise Bouts Across Standard School Days in Healthy Adolescents

Received: 30 March 2022;  Published: 15 August 2022;  doi: 10.21926/rpn.2203020

Abstract

Exercise-induced moderation of postprandial glycaemia in adolescents is unclear and has not been examined under free-living conditions. We assessed the effect of moderate-intensity exercise (MIE) and high-intensity intermittent exercise (HIIE) bouts on subsequent postprandial glycaemic responses across three standard school days. Fourteen healthy adolescents (13 ± 1 years) completed three conditions in the following order across consecutive days: MIE, 30-min continuous brisk walking; CON, no-exercise control; HIIE, [...]

1353 12037

Open Access Short Review

The Role of Vitamin D for Children with Inflammatory Bowel Disease

Received: 23 January 2022;  Published: 19 April 2022;  doi: 10.21926/rpn.2202013

Abstract

Children with inflammatory bowel disease (IBD) have a high prevalence of vitamin D insufficiency secondary to factors such as malabsorption and decreased intake. In recent years the benefits of optimal vitamin D status have been highlighted for their potential to improve the disease course and long-term outcomes in this population. Clinical benefits have been seen to bone health, the immune system, and gut health, with further improvements to disease and treatment outcomes. Recommendations for vitamin D treatment p [...]

1261 12027

Open Access Short Communication

Gut Microbiota Potentiates the Effect of Immune Checkpoint Therapy against Cancers

Received: 16 November 2021;  Published: 08 March 2022;  doi: 10.21926/rpn.2201007

Abstract

Immune checkpoints have been aggressively investigated for anti-cancer immunotherapy. The power of microbiota on the outcome of this immunotherapy has attracted much attention. For example, intestinal microorganisms play a key role in the effectiveness of programmed cell death 1 (PD1) and cytotoxic T lymphocyte-associated antigen 4 (CTLA4) blockade. Additionally, short-chain fatty acids produced in the gut may modulate anti-CTLA4 and anti-PD1 stimulated immune responses and their anti-tumor efficacy. Enhancing the [...]

1246 11750

Open Access Research Article

Pasta Fortification with Leaves of Edible Wild Plants to Lower the P Glycaemic Index of Handmade Fresh Noodles

Received: 30 March 2023;  Published: 07 June 2023;  doi: 10.21926/rpn.2302008

Abstract

Edible wild plants are a largely available food at no cost and an emblem of sustainability. Among the numerous varieties of edible wild plants, purslane (Portulaca oleracea L.) and common mallow (Malva sylvestris L.) are good sources of healthful bioactive compounds. Therefore, there is a growing interest in their consumption for health-related nutritional and sustainable perspectives. Fresh durum wheat tagliatelle fortified with dried and pulverized leaves of mallow or purslane at two distinct percentages of integ [...]

1818 11583

Open Access Case Report

The Low FODMAP Diet for Children with Inflammatory Bowel Disease and Overlapping Functional Gastrointestinal Symptoms – a Case Series

Received: 11 February 2023;  Published: 29 June 2023;  doi: 10.21926/rpn.2302009

Abstract

The low FODMAP diet (LFD) is a dietary intervention developed for and used particularly for the management of functional GI symptoms (FGIS) in adults with irritable bowel syndrome (IBS). It has also been proposed to improve coincident functional gut symptoms in adults with inflammatory bowel disease (IBD). This report describes the outcomes of the LFD in a series of children with IBD with concurrent FGIS. This study included children aged between 7-14 years with quiescent IBD and overlapping FGIS. All participants [...]

1044 11410

Open Access Original Research

Impact of the COVID-19 Pandemic Measures on the Number of Meals and the Types of Physical Activity of Adolescents: Cross-Sectional Study in Delhi, India

Received: 10 January 2022;  Published: 30 March 2022;  doi: 10.21926/rpn.2201010

Abstract

COVID-19 greatly affected the lives of adolescents through restrictions such as less playtime, more screen time, and limited interaction with peers. In this study, we assessed the impact of the COVID-19 pandemic on the dietary and physical activity-related behavior of school students aged 10–16 years. This cross-sectional study was conducted with adolescents recruited from seven randomly selected private schools in Delhi, India, during 2021. A self-administered web-based survey was conducted to evaluate the behavio [...]

1695 11383

Open Access Review

The Potential Role of Commensal Microbes in Optimizing Nutrition Care Delivery and Nutrient Metabolism

Received: 20 December 2021;  Published: 26 May 2022;  doi: 10.21926/rpn.2202014

Abstract

Microbes have been part of the diet throughout human history. In the evolution of food preservation practices, some techniques inadvertently leveraged microbial activity not only to extend the storage life but also to enhance the properties and nutritive value of foods. In the last century, a variety of bacterial species (referred to as probiotics) were found to confer health benefits to the host. The advent of high-throughput sequencing methods facilitated improved surveillance of conventional probiotics within gu [...]

1324 11337

Open Access Review

The Multifaceted Roles of Ketogenic Diets in Neurology-Brain Cancers and Other Neurologic Diseases

Received: 30 December 2021;  Published: 19 April 2023;  doi: 10.21926/rpn.2302007

Abstract

The ketogenic diet (KD) is currently well known in the lay media as a quick way to lose weight. However, the KD is not a new medical concept. The KD was used in the early 1900s to control seizures. However, as we developed more effective pharmacological agents, we used the KD less until it became practically obscure by the 1980s. Similar to the effects of fasting, the KD leads to the production of ketones as an alternative energy source to glucose. Therefore, the KD has many beneficial metabolic effects, such as an [...]

1176 10929

Open Access Review

Diet and Prevention of Cardiovascular Disease

Received: 28 January 2024;  Published: 16 August 2024;  doi: 10.21926/rpn.2403011

Abstract

Promoting a healthy diet is an effective strategy for preventing cardiovascular disease (CVD). The characteristics of a healthy diet are known. However, an unhealthy diet has become a significant contributor to the global burden of diseases, mainly due to its effect on CVD, diabetes, and cancer. A healthy diet is not accessible and affordable to most people worldwide. Marketing influences food choices and promotes unhealthy diets that contribute to obesity, CVD, diabetes mellitus, and cancer. Governments are respon [...]

1303 10922

Open Access Review

Practical Review on the Impact of Celiac Disease on the Patient

Received: 05 August 2022;  Published: 13 February 2023;  doi: 10.21926/rpn.2301003

Abstract

Celiac disease (CD) is a multisystem immune-mediated disorder resulting in enteropathy of the small intestine with the ingestion of gluten, in genetically susceptible individuals. This condition impact 1% of the population and can result in the development of other conditions such as chronic fatigue, anemia, osteoporosis, aphthous stomatitis, elevated liver enzymes, joint pain, infertility, peripheral neuropathy, and epilepsy. In this review, we outline the clinical presentation of CD, the physiological differences [...]

1225 10817

Open Access Commentary

Emerging Nutrition Approaches to Support the Mind and Muscle for Healthy Aging

Received: 24 August 2022;  Published: 16 November 2022;  doi: 10.21926/rpn.2204022

Abstract

This narrative review highlights recent advances and ongoing trials using nutrition approaches for healthy aging. Focus will be placed on nutrition therapies that target cognition (“the mind”) and mobility (“the muscle”), both critical components to maintaining a high quality of life for older adults. For “the mind,” two seemingly incongruent therapies are being investigated to improve cognition–the MIND diet (high in carbohydrates and anti-oxidant fruits and vegetables) and the ketogenic diet (low in carbohydrates [...]

1639 10626

Open Access Original Research

Ad Libitum Western Diet Feeding Does Not Alter Basal Skeletal Muscle Heat Shock Protein Expression in Sedentary or Aerobically Trained Young Rats

Received: 03 August 2021;  Published: 15 October 2021;  doi: 10.21926/rpn.2104001

Abstract

Poor dietary habits can lead to obesity and insulin resistance—both of which can impair basal heat shock protein (HSP) expression and the HSP stress response in skeletal muscle. It remains unclear if impairments in HSP expression occur during the early stages of diet-induced obesity and metabolic dysfunction. We determined if basal HSP expression (HSP70, HSP60, HSP25) was impaired in sedentary or exercised rats following the onset of diet-induced obesity. Male Long-Evans rats (N=6-7/group) were assigned to a [...]

1364 10596

Open Access Review

Nutrition Interventions in Aged Care: The Need and Challenges in the Aged Care Context

Received: 08 May 2024;  Published: 29 November 2024;  doi: 10.21926/rpn.2404019

Abstract

Malnutrition and frailty are preventable and reversible. However, a significant proportion of aged care residents live with malnutrition and frailty which have associated complications such as increased falls, hospitalizations, infections, and decreased quality of life. Nutrition and dietary interventions can prevent these issues, however, there a few interventions conducted in this setting and no consensus on the most utilized interventions to improve health outcomes. In a crude literature search, we identified 65 [...]

1989 10532

Open Access Review

The Relevance of Diet in Musculoskeletal Clinical Practice—A Narrative Review

Received: 16 May 2024;  Published: 27 September 2024;  doi: 10.21926/rpn.2403015

Abstract

Musculoskeletal (MSK) pain is a multifaceted problem, with many contributors. The assessment of these contributions by clinicians has evolved to include not only the musculoskeletal and nervous systems, but also psychosocial contributions. Nutrition, however, has not been considered as a potential contributor in the same way, despite a significant body of evidence showing that amending one’s diet may significantly reduce pain and inflammation. Historically, when the biomedical model was considered the gold standard [...]

724 10180

Open Access Review

Inclusion of Dietary-Fibers in Nutrition Provides Prebiotic Substrates to Probiotics for the Synthesis of Beneficial Metabolites SCFA to Sustain Gut Health Minimizing Risk of IBS, IBD, CRC

Received: 19 July 2023;  Published: 14 September 2023;  doi: 10.21926/rpn.2303017

Abstract

Usually, everyday meals constitute materials and ingredients for food preparation derived from different agricultural sources. Although most customers are aware of the benefits of a balanced diet, they mainly focus on a diet based on the daily requirements of protein, fat, and carbohydrates in their meals. However, the vital aspect of the including dietary fibers in diets is overlooked, which is equally important as is the daily requirement of calories and protein intake for maintaining the muscle mass. Some societ [...]

1287 10016

Open Access Original Research

Barley and Malt as Base Ingredients for the Production of New Bio-Functional Foods

Received: 14 April 2023;  Published: 19 September 2023;  doi: 10.21926/rpn.2303018

Abstract

This work aimed to evaluate the chemical composition, bioactive compounds (phenolics and γ-aminobutyric acid, GABA), and antioxidant properties of different barley varieties (Overture, Charles, Sinfonía, Montoya, and Andreia) and their malts to weigh up them as potential ingredients for producing new bio-functional foods. For this, five barleys and five malts obtained from them were studied. Regarding chemical composition, total starch was the main component (≈62%) of barleys followed by total di [...]

1277 10012

Open Access Review

Macroalgae as a Source of Functional Foods in the Prevention of Cardiovascular Diseases

Received: 22 July 2023;  Published: 29 November 2023;  doi: 10.21926/rpn.2304024

Abstract

Noncommunicable diseases (NCD), such as cardiovascular diseases (CVD), are responsible for the majority of annual deaths worldwide. Dyslipidemia, hypertension, diabetes, and obesity, among others, can enhance the onset of metabolic syndrome (MetS). The integration of natural products in the diet, such as marine macroalgae or hydrocolloids extracted from them, has been extensively studied. The application of these substances in the prevention of pathologies is expanding due to the high content of bioactive compounds [...]

1199 9838

Open Access Original Research

Association of Club Sports Participation and TV in the Bedroom with Dietary Pattern in Austrian Adolescents

Received: 15 November 2021;  Published: 18 February 2022;  doi: 10.21926/rpn.2201004

Abstract

Poor lifestyle choices in adolescents, including low physical activity (PA), excess screen time, and unhealthy dietary habits, are major threats to their health in the future. Unhealthy behaviors such as insufficient PA, high TV time, and poor dietary choices also tend to cluster, but information on the combined association of screen time, sports participation, and dietary habits is limited in Austrian youth. To examine the association among these behaviors, 165 adolescents (74 girls and 91 boys) between 11 and 14 [...]

1289 9764

Open Access Review

The Potential of Chickpea (Cicer arietinum L.) for Anti-Osteoporotic Agent in Post-Menopausal Women: A Systematic Review of In Vivo Study

Received: 09 April 2024;  Published: 23 August 2024;  doi: 10.21926/rpn.2403012

Abstract

This systematic review aimed to analyze the in vivo study of the anti-osteoporotic activity of chickpeas. A comprehensive search for English language papers published between January 2013 and December 2023 using the keywords chickpea or Cicer arietinum, anti-osteoporotic activity or anti-osteoporotic effect, chickpeas and anti-osteoporotic activity, Cicer arietinum and antiosteoporotic activity and their synonyms yielded 3566 results from PubMed, ScienceDirect, SpringerLink and Google Scholar. Articles were screene [...]

1222 9738

Open Access Review

Nutritional Health and Bioflavonoids

Received: 23 March 2022;  Published: 21 July 2022;  doi: 10.21926/rpn.2203017

Abstract

Flavonoids are phytochemicals (polyphenols) of plant origin. They can trap free oxygen radicals generated by mitochondria and other electronic transport chains, thereby inhibiting inflammatory and carcinogenic changes in vivo and in vitro. Why the body requires these compounds for the well-being of the organism and the maintenance of human health remains unclear. However, a deficit of flavonoids could lead to molecular malfunctions in cells, organelles, and macromolecules. This manuscript describes the occurrence a [...]

1093 9735

Open Access Original Research

Consumer Perception, Nutritional, and Technological Properties of Bread Made with Chickpea Flour

Received: 12 December 2022;  Published: 12 April 2023;  doi: 10.21926/rpn.2302006

Abstract

Celiac disease (CD) is one of the most common intestinal diseases in humans today. The only "cure" for this disease is a strictly gluten-free diet. Bread is a highly accepted food product. But, bread is a product that owns its technological properties to the presence of gluten. Bread without gluten has different texture, palatability, and sensorial properties. Therefore, new products are needed to solve this problem. Chickpeas are an inexpensive source of protein for making gluten-free baked goods. In this study, w [...]

1243 9354

Open Access Research Article

Influences of Household Processing Methods on Nutritional Composition, Anti-nutritional Factors and Antioxidant Activities of Foxtail Millet

Received: 17 July 2023;  Published: 09 November 2023;  doi: 10.21926/rpn.2304020

Abstract

The present investigation aims to study the influence of household processing methods, such as soaking, germination, and steam cooking, on nutritional composition (proximates, amino acids, minerals, and vitamins), antinutrient factors (phytochemicals: tannins, total phenols, phytic acid; enzyme inhibitors: trypsin and α-amylase inhibitors) and antioxidant properties of whole grains of foxtail millet. The contents of total ash (1.42%), fat (3.02 g/100 g), and mineral chromium (12.83 mg/100 g) were found to be [...]

1292 9233

Open Access Review

From Bioactive Molecules to Their Nutritional Effect, Biodynamic Interpretation Between Productional and Functional Aspects of Nutrients

Received: 10 October 2022;  Published: 21 December 2022;  doi: 10.21926/rpn.2204023

Abstract

In this article, the long journey from the production of food ingredients to their transformation into nutrients was described. The essential function of nutrients is to satisfy the primary needs of living organisms, namely energy, morphology and reproduction, through the consumption of food. Fulfilling its primary role, food must contain nutrients that are essential for the well-being of the living, along with others that are not essential but are still important for proper metabolism. These substances are known a [...]

1220 9222

Open Access Review

The Combined Effect of Infant and Mother Secretor Status on Infant Susceptibility to Viral Gastroenteritis and Celiac Disease

Received: 21 July 2022;  Published: 17 July 2023;  doi: 10.21926/rpn.2303012

Abstract

Celiac disease is a prevalent autoimmune disorder with a rising incidence of 7.5% annually during the second half of the 20th century and the 21st century. Not all genetically susceptible individuals that carry the risk alleles HLA DQ2 and DQ8 go on to develop celiac disease, suggesting that there may be other environmental triggers that contribute to the development of celiac disease in genetically susceptible individuals. Gastroenteritis during infancy has been shown to be associated with increased risk of celiac [...]

1254 8965

Open Access Original Research

Effects of a One-Week Intensive Wellness Camp on Dietary Behaviors among Southwest American Indian Youth

Received: 27 September 2022;  Published: 12 January 2023;  doi: 10.21926/rpn.2301002

Abstract

American Indians (AI) suffer the highest rates of diabetes in the United States (US); a chronic disease that is increasingly prevalent among AI children and is associated with increased risk of cancer. A summer camp was developed to improve disease risk-reducing behaviors, including diet, among AI youth in Arizona. The aim of this study was to examine the efficacy of a one-week intensive summer health camp conducted from 2016 to 2019 on change in dietary behaviors and compliance for Dietary Guidelines for Americans [...]

1434 8398

Open Access Original Research

Associations between Health-Related Behaviours, Well-Being, and Academic Performance of Secondary School Students with Special Educational Need: A Secondary Analysis

Received: 24 October 2022;  Published: 06 March 2023;  doi: 10.21926/rpn.2301005

Abstract

Health-related behaviours (HRBs) have been considered one of the most critical public health issues, especially for those with special educational needs (SEN). Previous research suggests that health-related behaviours are highly likely to impact well-being and academic achievement. Diet is a crucial health-related behaviour that needs to be investigated along with factors such as sleep and exercise. The present study used data from the Cornish Academies Project, and secondary analyses were conducted to investigate [...]

1074 8392

Open Access Short Communication

Home-Based Appetite-Guided Weaning of Enteral Nutrition of Infants with Congenital Heart Disease: A Preliminary Clinical Observation

Received: 13 January 2024;  Published: 19 April 2024;  doi: 10.21926/rpn.2402007

Abstract

Infants with a critical congenital heart defect are at high-risk for feeding difficulties, often necessitating feeding tube placement. Enteral nutrition (EN) support is initiated to meet nutritional requirements and promote growth pre- and post-operatively. Tube-fed infants with congenital heart disease (CHD) who achieve stable health status post-operatively are at risk of becoming feeding tube dependent (FTD). We report a clinical observation for infants with CHD based on survey results from Growing Independent Ea [...]

1436 8392

Open Access Case Report

Prolonged Maintenance of Remission with Crohn Disease Exclusion Diet (CDED) in Two Siblings with Crohn Disease

Received: 23 August 2024;  Published: 13 December 2024;  doi: 10.21926/rpn.2404020

Abstract

Dietary and nutritional interventions have been shown to have roles in managing active Crohn disease (CD), with exclusive enteral nutrition (EEN) being recommended as the preferred initial treatment in children following diagnosis. In recent years, other nutritional interventions such as the Crohn's disease exclusion diet (CDED) have been considered and evaluated for induction therapy. To date, the long-term benefits of CDED have not been established. This report highlights the outcomes of the prolonged use of CDED [...]

1088 8301

Open Access Perspective

A Natural Serotonin Stimulant for Appetite Suppression and Targeted Eating as an Alternative to Conventional Obesity Treatments

Received: 19 July 2024;  Published: 13 November 2024;  doi: 10.21926/rpn.2404018

Abstract

Recent advances in obesity management reflect the integration of pharmacological, surgical, and behavioral interventions, yet sustainable long-term outcomes remain elusive due to high attrition rates, the complexity of protocol compliance – and for some, costs, risks, and serious side effects. This research combined a patented nutraceutical designed to naturally stimulate serotonin, a biologic hunger agonist, to thereby aid in appetite control and facilitate weight loss through ‘Targeted Eating,’ a single, unrestri [...]

686 8205

Open Access Review

Hot Topics on Nutrition in IBD

Received: 04 January 2024;  Published: 19 March 2024;  doi: 10.21926/rpn.2401003

Abstract

Inflammatory bowel diseases (IBD) affect primarily the bowel, but they are multisystemic diseases with a wide range of extraintestinal manifestations and complications. Nutritional imbalance occurs frequently in patients with IBD. The spectrum of malnutrition goes from undernutrition (low protein-caloric intake, disease-related malnutrition, micronutrient deficiencies) to overnutrition and obesity. The nutritional status of patients with IBD is increasingly recognized as a key aspect of the treatment and must be ad [...]

1322 8114

Open Access Research Article

Teachers’ Perceptions of Integrating Tower Gardens into Pre-K4 Curriculum

Received: 31 August 2023;  Published: 17 January 2024;  doi: 10.21926/rpn.2401002

Abstract

Schools play an integral role in providing opportunities for children of all ages to be exposed to nutrition education. There are a variety of ways children can receive nutrition education in the school setting, such as explicit lessons, modeled dialogue, and exposure to nutrition-based principles. However, there continues to be a disconnect between teacher perceptions of nutrition education and time spent implementing it in the classroom. Nutrition education can come in many forms, including hands-on gardening and [...]

1347 8057

Open Access Original Research

Physicochemical Characterization and Mineral Composition of “UENF SD 08”: A Super-Sweet Corn Hybrid

Received: 30 December 2022;  Published: 27 August 2023;  doi: 10.21926/rpn.2303015

Abstract

Sweet Corn (Zea mays L.) is possibly the most important commercial cereal originating in the Americas. Mutant genes are responsible for sweetness. The purpose of this study was to evaluate the physicochemical and mineral composition of the “UENF SD 08” cultivar, super-sweet corn developed at Darcy Ribeiro Northern Rio de Janeiro State University (UENF) and registered in the National Cultivar Register of the Ministry of Agriculture, Livestock, and Supply and to compare its content to commercial super-swe [...]

1086 7976

Open Access Research Article

Bioactive Properties of Sorghum-based Beverages from Whole or Refined Grains

Received: 08 May 2023;  Published: 22 August 2023;  doi: 10.21926/rpn.2303013

Abstract

Sorghum-based beverages were developed and the effects of decortication on nutritional composition and biofunctional properties after a simulated gastrointestinal digestion were analyzed. For that, white sorghum flours from whole (WS) and decorticated (DS) grains were obtained and used to prepare sorghum beverages. They were analyzed regarding chemical composition, minerals, and phenolic acid contents. Moreover, the bioaccessibility of phenolics, proteins, and the potential bioactivity (ABTS+ scavenging, ACE-I inhi [...]

1120 7944

Open Access Review

“Guess Who?” in the Creation of Hazardous and Non-Hazardous Diets through History

Received: 17 November 2023;  Published: 03 April 2024;  doi: 10.21926/rpn.2402005

Abstract

The relationship between obesity and weight loss treatments has run parallel throughout history; however, not all diets are suitable for improving one’s health. This review aims to categorize diets according to the new classification of hazardous diets established in 2021. A search was conducted across grey, white, and black literature. The results reveal a study of 179 diets, of which 35 are effective, while the rest are hazardous to health. Looking at the geographical distribution of these diets, the USA, the UK, [...]

917 7795

Open Access Original Research

Exploring the Use of Purple Corn Cob Flour as a New Fiber Source in Pan Bread Improved by Commercial Hemicellulases

Received: 08 May 2024;  Published: 05 September 2024;  doi: 10.21926/rpn.2403013

Abstract

Bread stands out for its versatility and accessibility, appealing to individuals across various ages and social classes. Consequently, it presents an attractive opportunity for incorporating ingredients that offer health benefits to consumers. In this context, the current study aimed to evaluate the technological properties of sandwich bread (specific volume, water activity, moisture, instrumental color, and texture) prepared with a partial substitution (5% w/w) of wheat flour (WF) with purple corn cob flour (PCF) [...]

1186 7279

Open Access Original Research

Impact of Breeding on Free Amino Acids of Wholegrain Flour in Wheat and Role of Phenology Genes

Received: 18 August 2023;  Published: 24 November 2023;  doi: 10.21926/rpn.2304023

Abstract

Wheat (Triticum aestivum L.) is pivotal to global food security, with its energy-rich grains that are also the major vegetable protein source in human diets. Decades of primary emphasis on grain yield improvement have delivered increased gains worldwide, but the grain protein content has declined. Since amino acids are biosynthetic precursors of proteins, this research hypothesized that their contents in the wholegrain flour have also been impacted by past wheat breeding. To test this, the free amino acid content o [...]

1270 7162

Open Access Review

Nutritional Profile and Topic Management for Wound Healing in Children with Epidermolysis Bullosa: What Is the Evidence? A Systematic Review

Received: 11 April 2024;  Published: 17 July 2024;  doi: 10.21926/rpn.2403010

Abstract

Epidermolysis Bullosa (EB) is a rare genetic disorder characterized by fragile skin that blisters and tears easily, leading to significant morbidity and mortality. Depending on the specific genetic mutations and the proteins involved, EB can be classified into several subtypes whose molecular complexity is compounded by the variability in mutation types (missense, nonsense, insertions, deletions), their locations within the genes, and the resultant effects on protein function. This systematic review aimed to identi [...]

1364 7082

Open Access Original Research

The Fat Level in the Breast Milk and Its Association with Dietary Intake and Body Mass Index of Breastfeeding Mothers in Central Ethiopia, 2017

Received: 24 July 2024;  Published: 24 December 2024;  doi: 10.21926/rpn.2404021

Abstract

Human milk is not static; it is an invariant fluid that fluctuates in micro and macronutrient composition during feeding. The fat in human milk contributes above half the energy the infant demands. Moreover, fat is one of the most essential nutrients for brain tissue development during infancy. However, the effect of maternal nutritional status, including dietary intake, on human milk fat levels is not well investigated, particularly in developing nations. This study aimed to assess the level of human milk fat and [...]

1581 7052

Open Access Review

Potential of Nutritious Indian Medicinal Plants to Boost Immunity in the Aftermath of Pandemics: A SWOC Analysis

Received: 23 August 2023;  Published: 26 March 2024;  doi: 10.21926/rpn.2401004

Abstract

The world has suffered a lot during the COVID-19 pandemic, for which nobody was prepared. Due to the lack of appropriate treatment, Indian medicinal plants have alleviated the burden due to their diverse health benefits. It has been observed that certain medicinal plants can effectively enhance immunity against microorganisms and viruses. Numerous scientific studies have supported the above claims. This paper presents the SWOC analysis of Indian medicinal plants for their immunity-enhancing effects so that the medi [...]

1064 6655

Open Access Review

Physiological Impact of Milk on Multiple Health Outcomes in Human

Received: 19 December 2024;  Published: 20 August 2025;  doi: 10.21926/rpn.2503016

Abstract

Milk is best known as a nutrient-rich fluid produced by the mammary glands of mammals, designed primarily to feed young. In the human diet, cow milk is most prevalent, but milk of other mammals and plant milk are common too. This study aims to investigate milk's nutritional value in various age groups and review opposing evidence of its effect on cardiovascular diseases in adults. It is a literature-based strategy to synthesize information from observational and meta-analytic studies. The milk content—macronutrient [...]

1337 6574

Open Access Original Research

Household Exposure to Secondhand Cigarette Smoke during Pregnancy and Adverse Offspring Health Outcomes in The Gambia: A Cross-Sectional Study

Received: 31 August 2024;  Published: 08 April 2025;  doi: 10.21926/rpn.2502006

Abstract

The adverse effects of maternal passive smoking during pregnancy on offspring health remain understudied in sub-Saharan Africa, particularly in The Gambia, where smoke-free regulations are limited. To determine the prevalence of maternal passive smoking (MPS) during pregnancy and investigate its associations with adverse pregnancy outcomes and offspring health complications in The Gambia. A cross-sectional study was conducted in February 2023 among 401 mothers with children under 5 years in urban and rural regions [...]

768 6533

Open Access Original Research

Dietary Fiber in Preventing Non-Communicable Diseases: Predicting Prevented Deaths and Economic Impact through the Use of Algae as a Fiber Source

Received: 30 August 2023;  Published: 15 April 2024;  doi: 10.21926/rpn.2402006

Abstract

Non-communicable diseases (NCDs) are responsible for two-thirds of premature deaths in Europe. This added to the European socio-economic scenario already weakened by the vital aging of the population, contributes to the loss of active individuals, weakening competitiveness and social and economic sustainability, thus making the prevention of NCDs a European objective. Preventing NCDs with the enrichment of the food environment using algae or their compounds, which are rich in nutrients and bioactivities, is an exce [...]

1241 6169

Open Access Original Research

The Importance of Specialized Inpatient Medical Stabilization for Weight Restoration of Individuals with Extreme Eating Disorders

Received: 19 December 2024;  Published: 23 May 2025;  doi: 10.21926/rpn.2502012

Abstract

Inpatient care is a significant contributor to the health-care costs associated with the treatment of individuals with eating disorders (EDs). This study seeks to better understand the treatment outcomes of individuals with extreme EDs requiring inpatient medical stabilization at specialized medical versus nonspecialized medical units. Patients transferred via air ambulance to ACUTE Center for Eating Disorders and Severe Malnutrition (specialized care) from an outside hospital (nonspecialized care) between January [...]

567 6062

Open Access Review

The Crucial Role of Vitamin D in Regulating Gut Microbiota in Inflammatory Bowel Disease

Received: 17 November 2024;  Published: 08 April 2025;  doi: 10.21926/rpn.2502007

Abstract

In recent years, there has been an alarming increase in the incidence of inflammatory bowel disease (IBD), which includes both Crohn's disease (CD) and ulcerative colitis (UC), particularly in Western countries. This chronic condition is intricately linked to the composition and health of the gut microbiota (GM) — a complex community of microorganisms residing in the gastrointestinal (GI) tract. Despite extensive research, the underlying pathogenesis of IBD remains poorly understood, making it a wide area of invest [...]

767 5982

Open Access Research Article

Physicochemical Characterization of Fresh and Powdered Tomato in Arba Minch, Ethiopia

Received: 07 January 2025;  Published: 02 June 2025;  doi: 10.21926/rpn.2502013

Abstract

Tomato (Solanum lycopersicum L.) is the largest vegetable crop produced and consumed in the world. Tomatoes are a top source of Vitamin A and C, contain more dietary fibre, beta-carotene, iron, lycopene, magnesium, niacin, potassium, phosphorus, riboflavin, and thiamine. Tomatoes have a limited shelf life in ambient conditions and are highly perishable. It creates glut during the production season and becomes scanty during the off-season. Short shelf life, coupled with inadequate processing facilities results in he [...]

931 5921

Open Access Original Research

Impact of Feeding Time and Duration on Body Mass and Composition in Young, Exercising Mice

Received: 21 December 2022;  Published: 22 August 2023;  doi: 10.21926/rpn.2303014

Abstract

Time-restricted feeding (TRF) has increased in popularity among various groups, including fitness enthusiasts. The ideal timing of TRF in relation to daily exercise is unknown. Most fitness enthusiasts consume meals immediately or soon after exercise to improve body composition (e.g., lean mass). We compared two different TRF approaches, as well as an ad libitum control diet, with regards to body mass and body composition in C57BL/6 mice. Young, healthy, male mice exercised five days per week and were assigned to c [...]

844 5868

Open Access Editorial

Acknowledgment to Reviewers of Recent Progress in Nutrition in 2022

Received: 05 January 2023;  Published: 05 January 2023;  doi: 10.21926/rpn.2301001

Abstract

The editors of Recent Progress in Nutrition would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2022. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers receive a voucher entitling them to a discount on their next LIDSEN publication and can download a certificate of re [...]

862 5684

Open Access Review

Impact of Heavy Metals as Trace Elements on the Ecosystem and Health

Received: 10 June 2025;  Published: 21 October 2025;  doi: 10.21926/rpn.2504023

Abstract

Heavy metals are integral parts of our environment, originating initially from the universe and used in the industry, which may contribute to pollution. This book chapter aims to address the impact of heavy metals on the ecosystem and human health. Among the 32 heavy metals, eight belong to the group of essential ones: cobalt, copper, iron, manganese, molybdenum, nickel, selenium, and zinc. They were necessary in physiological amounts for the evolution of flora and fauna, including humans on earth, and are still ne [...]

628 4994

Open Access Original Research

Location, Season and Source Effects on Gross Composition of Raw Cow’s Milk Across Khartoum State, Sudan

Received: 06 April 2024;  Published: 27 April 2025;  doi: 10.21926/rpn.2502009

Abstract

This study was conducted to investigate the effect of sources. locations and seasons (late summer and winter) on the chemical composition of cow milk collected from Khartoum State. The samples were collected randomly in the morning or the evening. Two hundred and seventy milk samples were collected from farms (90 samples), groceries (90 samples) and vendors (90 samples) in Khartoum State during the late summer and winter seasons, 135 samples each. The milk samples were kept in cool cracked ice and transported immed [...]

557 4670

Open Access Case Report

Cyclic Exclusive Enteral Nutrition as an Alternative to Medical Maintenance in Crohn Disease—A Case Report

Received: 10 July 2024;  Published: 24 October 2024;  doi: 10.21926/rpn.2404017

Abstract

We present a case report of an 11-year-old girl diagnosed with Crohn’s Disease and managed with maintenance cyclic exclusive enteral nutrition with satisfactory long-term biochemical and symptomatic control.

804 4630

Open Access Review

The Impact of Vitamin D on Type 2 Diabetes Mellitus: Exploring Its Role in Glucose Metabolism and Insulin Sensitivity

Received: 15 May 2025;  Published: 29 September 2025;  doi: 10.21926/rpn.2503021

Abstract

Vitamin D, a fat-soluble secosteroid, plays a pivotal role beyond its functions in calcium and bone homeostasis. Emerging evidence suggests its involvement in glucose metabolism and insulin sensitivity, thus influencing the pathophysiology of Type 2 Diabetes Mellitus (T2DM). For the current review, a search was conducted across four major databases: PubMed, Embase, Google Scholar, and Web of Science. The aim was to identify relevant studies and clinical trials, published in English, reporting the mechanistic insigh [...]

605 4558

Open Access Editorial

Nutritional Guidance for Individuals with Prediabetes — Uniform or Tailored to Phenotypes?

Received: 15 April 2024;  Published: 23 April 2024;  doi: 10.21926/rpn.2402008

924 4527

Open Access Editorial

Acknowledgment to Reviewers of Recent Progress in Nutrition in 2023

Received: 04 January 2024;  Published: 05 January 2024;  doi: 10.21926/rpn.2401001

Abstract

The editors of Recent Progress in Nutrition would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2023. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers can download a certificate of recognition directly from our submission system. Additionally, reviewers can sign up t [...]

735 4094

Open Access Original Research

Attenuation of Blood Glucose by the Ketone Monoester (R)-3-betahydroxybutyrate Glyceride in Healthy Male Sprague Dawley Rats in Response to a Standard Oral Glucose Tolerance Test

Received: 31 January 2025;  Published: 25 July 2025;  doi: 10.21926/rpn.2503014

Abstract

Efficient glucose uptake by peripheral tissue is important for individuals who desire to maintain optimal wellbeing. Various methods to regulate postprandial blood glucose have been reported in the research literature, however, few have examined the effect of ketone esters on blood glucose levels. The present study evaluated blood glucose following the administration of an oral glucose tolerance test, with and without ketone esters delivered at two different dosages, in a sample of healthy Sprague-Dawley rats. We h [...]

654 4032

Open Access Original Research

Identification of Soybean Components that Prevent the Entry of Influenza Virus

Received: 31 August 2024;  Published: 01 April 2025;  doi: 10.21926/rpn.2502005

Abstract

We have previously demonstrated the anti-influenza virus activity of a soybean extract, indicating the presence of compounds that prevent viral entry into cells. In this study, we sought to identify the compounds in hydrothermal extracts of soybean that blocked viral entrance and analyzed their mechanisms of action. Hot aqueous extracts of roasted soybeans were separated by reverse-phase chromatography on an octadecylsilyl C18 column, and the antiviral activity of individual fractions was measured during the viral [...]

679 3874

Open Access Interview

An Interview with Prof. Corrado I. Angelini

Received: 17 April 2025;  Published: 22 April 2025;  doi: 10.21926/rpn.2502008

484 3241

Open Access Review

Engaging with an Industrial Pandemic: Drivers of and Responses to the Expansion of Ultra-Processed Foods in East and Southern Africa

Received: 14 January 2025;  Published: 29 August 2025;  doi: 10.21926/rpn.2503018

Abstract

Intensified marketing and expanding consumption of ultra-processed foods (UPFs) that contain high sugar, salt, trans-fats and other additives and sugar sweetened beverages in Sub-Saharan Africa (SSA) are associated with rising obesogenic environments and non-communicable diseases, termed by some an ‘industrial pandemic’ due to its commercial drivers and cross border nature. This review paper addresses the question of how far SSA, positioned at an early point of a rising wave, is controlling this growing health chal [...]

566 3205

Open Access Original Research

The Contribution of Dietary Fatty Acids to Prediction of All-Cause Mortality in a Cohort of Middle-Aged Men Followed-Up for 61 Years Until Extinction

Received: 09 November 2024;  Published: 19 May 2025;  doi: 10.21926/rpn.2502011

Abstract

To describe the contribution of three classes of dietary fatty acids to all-cause mortality and age at death among middle-aged men followed up for 61 years until extinction. The cohort comprised 1712 men aged 40-59 years at entry examination in 1960, belonging to the Italian Rural Areas of the Seven Countries Study of Cardiovascular Diseases. A dietary survey allowed to estimate dietary fatty acids [saturated (SAFA), mono-unsaturated (MUFA), poly-unsaturated (PUFA) and their ratios (M/S, P/S)] that were fed as poss [...]

604 3152

Open Access Original Research

Germination-Induced Starch Influence on Structural Characteristics of Water-Soluble Extracts from Purple Pericarp Creole Corn

Received: 14 October 2024;  Published: 28 July 2025;  doi: 10.21926/rpn.2503015

Abstract

Germination is a viable, cost-effective, and environmentally friendly biotechnological process that enhances the industrial applications of cereals. This study evaluated the impact of germination (86 hours at 30°C) on soluble solids, proximate composition, and total phenolic compounds (TPC) in water-soluble extracts. It also included imaging analyses using scanning electron microscopy (SEM), X-ray diffraction (XRD), apparent amylose content, and starch pasting properties of purple pericarp Creole corn (PPCC) fr [...]

579 3039

Open Access Editorial

Acknowledgment to Reviewers of Recent Progress in Nutrition in 2024

Received: 02 January 2025;  Published: 02 January 2025;  doi: 10.21926/rpn.2501001

Abstract

The editors of Recent Progress in Nutrition would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2024. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers can download a certificate of recognition directly from our submission system. Additionally, reviewers can sign up t [...]

468 2868

Open Access Review

Clinical Trials Characterizing the Serum 25-Hydroxyvitamin D Response to Vitamin D Supplementation in Children: A Systematic Review and Meta-Analysis

Received: 13 September 2024;  Published: 29 October 2025;  doi: 10.21926/rpn.2504024

Abstract

Recommendations for vitamin D supplementation are essential for the prevention and therapy of vitamin D deficiency. However, reliable data remain lacking for children, as most intake recommendations are based on individual studies. This work aimed to obtain reliable data that allow health authorities to re-evaluate recommendations for oral vitamin D uptake in children. We conducted a systematic literature search in MEDLINE/PubMed on vitamin D supplementation in children. All randomized controlled trials (RCTs) publ [...]

366 2430

Open Access Original Research

Preliminary Comparative Sodium Analysis of Different Tempeh Types in Indonesia and Its Benefits for Hemodialysis

Received: 01 April 2025;  Published: 19 September 2025;  doi: 10.21926/rpn.2503020

Abstract

Hemodialysis patients require a diet rich in protein that is easily digestible, such as tempeh. Tempeh is a local Indonesian food product that can be purchased at a low price. Tempeh has a low sodium content, but there has never been an analysis related to the difference in sodium content in local Indonesian soybean tempeh products and imported soybean tempeh. This study was to compare the sodium analysis of different tempeh types in Indonesia as a preliminary study for the subsequent research to fulfill a high-pro [...]

352 2319

Open Access Interview

An Interview with Prof. Andrew S Day

Received: 24 February 2025;  Published: 25 February 2025;  doi: 10.21926/rpn.2501003

431 2260

Open Access Interview

An Interview with Prof. Rosita Gabbianelli

Received: 24 August 2025;  Published: 27 August 2025;  doi: 10.21926/rpn.2503017

Abstract

An Interview with Prof. Rosita Gabbianelli

287 1757

Open Access Interview

An Interview with Dr. Blanca Hernandez-Ledesma

Received: 28 August 2025;  Published: 09 October 2025;  doi: 10.21926/rpn.2504022

212 1057

Open Access Original Research

Occurrence of Multidrug Resistant Escherichia coli & Escherichia coli O157:H7 in Raw Cow Milk from Dhaka, Bangladesh

Received: 01 May 2025;  Published: 09 December 2025;  doi: 10.21926/rpn.2504025

Abstract

Enteropathogenic strains of Escherichia coli, like the serotype O157:H7, can cause significant health issues if consumed. Milk and dairy products can serve as a reservoir for the bacteria. Dissemination of multidrug-resistant E. coli through dairy products can become a potential health hazard if consumed. The present study investigates the occurrence of multidrug-resistant E. coli O157:H7 in raw milk obtained from farms and markets around Dhaka, Bangladesh. A Total of 50 milk samples were collected in this study fr [...]

75 357

Newsletter  

TOP