Table of Content

Open Access Review

Advances in Human Islet Processing: Manufacturing Steps to Achieve Predictable Islet Outcomes from Research Pancreases

Received: 15 October 2018;  Published: 26 February 2019;  doi: 10.21926/obm.transplant.1901052

Abstract

Background: This presentation of a six-year study processing human islets for research and transplantation includes a review of multi-center transplant studies identifying key variables critical for successful islet processing and defines standardized processing procedures required to provide highly purified, functional Human Islets. Methods: Human islet processing methods are defined in detail with pancreas retrieval, shipping, trimming for processing, collagenase distension, controlled digestion by digestion/filt [...]

2143 16215

Open Access Research Article

Variation of CO2-Brine Contact Angles on Natural Rocks of Different Compositions

Received: 05 September 2021;  Published: 05 November 2021;  doi: 10.21926/jept.2104046

Abstract

Contact angles were measured for CO2-brine interactions on 20 different rocks that represent the properties of various CO2 storage depositional environments to characterize the wettability during geologic carbon storage. Three different CO2 phases (gaseous, liquid, and supercritical) were considered to investigate the effect of pressure and temperature. Bubbles were studied in two groups of larger and smaller than 500 μm, the latter being more relevant to pore scale. Variation was observed among contact angle measu [...]

2730 16171

Open Access Research Article

Spousal Dementia Grief: A Research Report from the Two-Track Model of Dementia Grief Project

Received: 07 September 2020;  Published: 12 March 2021;  doi: 10.21926/obm.geriatr.2101160

Abstract

Caregiving for a loved one suffering from cognitive decline involves coping with many challenges and losses. This experience increases the risk of worsening the physical and mental health of the caregiver and has been the subject of a substantial number of studies focusing on the stress and burden of the primary caretaker. Theory and research on the grief reactions experienced by the family members, however, continues to lag in terms of the attention given to the behavioral and psychological burden of caregivers. T [...]

1929 16168

Open Access Original Research

Epigenetic Symmetry of DLGAP2: Pre-Implantation Maternal Methylation Switches to a Random Monoallelic Profile in Somatic Tissues

Received: 29 May 2018;  Published: 29 July 2018;  doi: 10.21926/obm.genet.1803026

Abstract

Background: Symmetrical DNA methylation profiles of autosomal genes are associated with equal expression by both alleles. Genes with an allelic imbalance or monoallelic expression are associated with discrete intervals of allele-specific methylation (ASM), as highlighted by genomic imprinting, X-chromosome inactivation and genotype-driven ASM. However, a more complex pattern has been described in which random monoallelic methylation provides cells with a unique mechanism for modulating allelic dosage. Methods: We c [...]

2224 16151

Open Access Concept Paper

Correction of Sunglint Effects in High Spatial Resolution Hyperspectral Imagery Using SWIR or NIR Bands and Taking Account of Spectral Variation of Refractive Index of Water

Received: 26 April 2021;  Published: 05 July 2021;  doi: 10.21926/aeer.2103017

Abstract

Passive high spatial resolution hyperspectral and multispectral imaging systems in the solar spectral region from aircraft and satellite platforms are being increasingly used for remote sensing of coastal waters and inland lakes. However, the remotely sensed data are often contaminated by the specular reflection of solar radiation at the air/water interface. Thus, the effects of sunglint need to be corrected. The purpose of sunglint correction is to remove the undesired specular reflected portion of radiance that d [...]

2573 16123

Open Access Review

Vanadium: Biological, Environmental, and Engineering Aspects

Received: 18 December 2019;  Published: 08 January 2020;  doi: 10.21926/acr.2001002

Abstract

Vanadium is an element that is widely distributed in Earth’s crust as well as in sea-water and ground-water reservoirs. Therefore, it exerts a great influence on the issues related to life and environment. Vanadium is utilized by several marine organisms. For example, there are vanadate-dependent haloperoxidases in algae and several bacteria, e.g., Azotobacter, use it for nitrogen fixation and bacterial reduction involves the conversion of vanadate to oxidovanadium (IV). The similarity between vanadate and phosphat [...]

1771 16122

Open Access Review

Short Sleep in Pupils in Japan: Current Status and Associated Factors

Received: 21 February 2019;  Published: 22 July 2019;  doi: 10.21926/obm.neurobiol.1903034

Abstract

Background: Several recommendations on optimum sleep duration have been published for adolescents to secure a healthy life. This study aimed to compare the sleep duration of middle and high school pupils in Japan with the recommended values and determined the factors associated with the duration of sleep among them. Methods: A total of 1766 completed questionnaires were obtained from grades 7 to 12 pupils in Japan. The questionnaire addressed the following points: sleeping, eating, defecation, physical activity, sc [...]

1583 16115

Open Access Review

Treatment Strategies for Antibody-mediated Rejection in Kidney Transplantation and Its Prevention

Received: 22 August 2020;  Published: 28 September 2020;  doi: 10.21926/obm.transplant.2003119

Abstract

This article reviews the current treatment strategies of antibody-mediated rejection in kidney transplantation, which is increasingly recognized as the leading immunological cause of graft failure. The pathophysiologic complexity of this condition poses significant challenges for its treatment; however, progress toward advancing our understanding of its pathogenesis and diagnosis will allow for identification of new therapeutic targets. Emphasis is also given to prevention, which is mainly based on careful assessme [...]

1510 16075

Open Access Review

Clinical Approach to the Management of Infections before and after Liver Transplantation

Received: 14 February 2020;  Published: 11 May 2020;  doi: 10.21926/obm.transplant.2002108

Abstract

The infectious complications before and after liver transplant (LT) are affected by the severity of liver disease and immunosuppression intensity after transplantation. Both cirrhosis and immunosuppression contribute to dysfunction of defensive mechanisms of the host. When a patient is evaluated for transplantation, the opportunity arises to assess the individual’s risk for infection and how one may modify those risks through prophylactic and therapeutic strategies. Pretransplant infectious disease evaluation focus [...]

2009 16058

Open Access Original Research

Newborn Screening Programs: Next Generation Ethical and Social Issues

Received: 19 October 2017;  Published: 14 August 2018;  doi: 10.21926/obm.genet.1803027

Abstract

The benefits of neonatal screening programs are undeniable: children’s lives are saved, and disease burden and morbidity alleviated. Without a doubt, « classical » neonatal screening programs are in the best interests of newborns. Indeed, those screening programs are recognized among the ten most important public health achievements. However, newborn screening programs raise ethical, legal and social challenges. For example, which criteria should govern whether or not to include a disease in the list of screened co [...]

2177 16044

Open Access Original Research

Cognitive and Physical Indicators of Gait Speed in the Community-dwelling Older Adult

Received: 16 November 2021;  Published: 15 February 2022;  doi: 10.21926/obm.geriatr.2201188

Abstract

Gait speed has been correlated to quality of life and has been called the sixth vital sign. The purpose of this study was to understand the factors that comprise fast and comfortable gait speed. 90 older adults provided demographic, cognitive, and functional performance data. Hierarchical linear regression models revealed predictors for comfortable gait speed to be lower-extremity strength ( B = 1.13, β = 0.233, P< .05), comorbid health ( B = −2.95, β = −0.22, P < 0.05), and gender( B = [...]

1492 16039

Open Access Case Report

Increased Recurrence Risk in Phelan-McDermid (22q13.3 Deletion) Syndrome: the Importance of FISH Demonstrated by a Case Series of Five Families

Received: 13 July 2018;  Published: 21 November 2018;  doi: 10.21926/obm.genet.1804050

Abstract

Background: Phelan-McDermid syndrome (PMS), or 22q13.3 deletion syndrome, is a neurodevelopmental disorder with an estimated prevalence of 1 in 10,000 to 1 in 20,000 newborns. Although it usually occurs de novo with a low recurrence risk, an increased recurrence risk is observed in some families. In this paper, we provide an overview of the underlying causes of increased recurrence risk in families with PMS and present a workflow aimed at identifying an increased recurrence risk. Methods: First, we report clinical [...]

2645 16031

Open Access Communication

Therapeutic Musical Scales: Theory and Practice

Received: 19 November 2020;  Published: 24 May 2021;  doi: 10.21926/obm.icm.2102019

Abstract

Using musical scales in a therapeutic key is one of the fundamental music therapy techniques of the Yoga of Sound (Nāda Yoga). The practice consists of singing particular sound formulas (scales), which are devised on a logical mathematical basis formed by specific musical intervals. These scales can bring to the surface, in a clear (objective), recognizable, and predictable way, psycho-emotional states and transform the blocked emotional energies. These blocked emotional energies are caused by repeated emotional st [...]

2164 16021

Open Access Case Report

Tongue Acupuncture as an Alternative Method for Treating Rosacea–A Case Report

Received: 29 December 2019;  Published: 15 April 2020;  doi: 10.21926/obm.icm.2002021

Abstract

Rosacea is a chronic inflammatory disease of the skin characterized by facial papules, pustules, erythema, and telangiectasia. Emotional factors such as stress and anxiety may induce and aggravate the symptoms of rosacea. It is hypothesized that tongue acupuncture, a technique that has been used successfully in the treatment of various neurological and psychiatric diseases, could be beneficial in relieving rosacea symptoms. This study evaluated the immediate effect of tongue acupuncture at specific anatomical point [...]

2016 15971

Open Access Review

Current Progress in Cancer Immunotherapies Using Small Molecules Targeting PD-L1 Stability

Received: 11 January 2021;  Published: 24 March 2021;  doi: 10.21926/obm.genet.2101127

Abstract

PD-L1 is an immune checkpoint protein that is frequently overexpressed by the cells in the tumor microenvironment. PD-L1 binds to PD-1 present on the activated antitumor T-cells, which allows for tumor immune escape. The ability of the PD-1/PD-L1 axis to suppress antitumor immunity enables its application as a potential target for small-molecule-based immunotherapies. Targeting the PD-L1-mediated tumor immune evasion represents a promising approach for immune checkpoint blockade therapies. However, the existing mon [...]

2101 15968

Open Access Review

Technological Resources for Early Intervention in Cases of Dyscalculia: A Deductive-Inductive Categorization

Received: 29 May 2023;  Published: 23 October 2023;  doi: 10.21926/obm.neurobiol.2304191

Abstract

Dyscalculia is a math learning disability that significantly interferes with students' academic performance and math-related aspects of their daily lives. Early diagnosis and the design of intervention programs adapted to the needs of each case are essential. In this sense, multiple technological resources are created to address both issues. Still, it is difficult to identify which characteristics they share and which are more relevant regarding didactic suitability. Given this situation, this research proposes cat [...]

1988 15934

Open Access Review

A Delirium Monitoring Program for Hospitalized Older Adults: An Approach to Age-Friendly Health Systems

Received: 05 May 2020;  Published: 13 July 2020;  doi: 10.21926/obm.geriatr.2003128

Abstract

Delirium is an acute change in mental status with key features of inattention and disorganized thinking. It is particularly common in older adults, with multiple and varied causes. Delirium increases the risk of morbidity, mortality, institutionalization, and healthcare costs; however, it is often missed because it is difficult to recognize without the use of a validated screening tool. The Age-Friendly Health Systems (AFHS) initiative highlights the need for implementation of a delirium monitoring program in hospi [...]

2272 15929

Open Access Review

Informatics and Artificial Intelligence Approaches that Promote Use of Integrative Health Therapies in Nursing Practice: A Scoping Review

Received: 30 December 2019;  Published: 17 February 2020;  doi: 10.21926/obm.icm.2001006

Abstract

Integrative health (IH) therapies are increasingly used to manage health conditions, but barriers hindering nurses from offering IH therapies persist. Informatics and artificial intelligence (AI) approaches have potential to promote nurses’ professional use of IH therapies. The purposes of this review are to (1) describe the state of the science of informatics and AI approaches promoting nurses’ use of IH therapies and (2) identify gaps in literature for future investigations. This systematic scoping review followe [...]

3179 15918

Open Access Research Article

Implementation of a Whole-School Mindfulness Curriculum in an Urban Elementary School: Tier 1 through Tier 3

Received: 27 November 2022;  Published: 24 May 2023;  doi: 10.21926/obm.icm.2302022

Abstract

Mindful education (ME) in schools can address student well-being and stressors, as well as improve the overall school environment. Implementing a whole-school mindfulness curriculum can be challenging, especially when serving students in both general education and emotional behavioral disorder (EBD) settings. We investigated the feasibility, implementation, and benefits of a whole-school mindfulness curriculum (MindUP) in an urban elementary school. This study is unique in that it investigated how to implement mind [...]

2094 15902

Open Access Communication

Meditation as an Intervention for Health: A Framework for Understanding Meditation Research

Received: 30 July 2018;  Published: 09 October 2018;  doi: 10.21926/obm.icm.1804025

Abstract

We propose a framework for understanding meditation that can support greater scientific rigor in reporting meditation research, and selecting meditation health interventions. There is no consistent and thorough framework for describing meditation research interventions. This impedes rigor of meditation research design and interpretation of findings. This also limits meaningful comparisons across research studies. The audience for this article includes researchers, meditation experts, healthcare professionals, and t [...]

2946 15870

Open Access Review

Green Energy Sources Reduce Carbon Footprint of Oil & Gas Industry Processes: A Review

Received: 25 September 2022;  Published: 28 January 2023;  doi: 10.21926/jept.2301004

Abstract

In recent years, the oil and gas sector has been moving towards green production methods to achieve net-zero emission goals. Governments and corporations have started large-scale initiatives to deploy advanced technologies to reduce carbon footprints and prevent global warming. Herein, we have explored the emerging techniques and methods used in reducing the effects of gas emissions in the oil and gas industry. The transition process from hydrocarbons to renewable energy resources, including solar thermal applicati [...]

2379 15861

Open Access Review

The Roles of Inflammation, Oxidative Stress and the Gut-Brain Axis in Treatment Refractory Depression in Youth: Complementary and Integrative Medicine Interventions

Received: 06 April 2020;  Published: 19 October 2020;  doi: 10.21926/obm.icm.2004040

Abstract

Teen depression and suicide rates have risen despite conventional treatments. This article reviews adjunctive interventions that may improve outcomes. A search of the National Library of Medicine database used tailored searches with combinations of specific terms. Modern lifestyle is associated with increased inflammation and pro-inflammatory cytokines leading to, for instance, hyperactivation of the hypothalamic-pituitary-adrenal axis, which promotes depression. Inflammation also increases oxidative stress, leadin [...]

3313 15843

Open Access Original Research

A Systematic Review about Building Characteristics as Dampness-Related Indicators

Received: 05 October 2023;  Published: 29 February 2024;  doi: 10.21926/aeer.2401008

Abstract

The consistent associations between dampness and health-related problems, such as allergies and asthma symptoms, explain the growing scientific interest in assessing housing characteristics. Due to a growing interest in the built environment, the present study performed a systematic review to investigate the prevalence of dampness related to specific building characteristics. The built environment is gaining significance in population well-being due to the substantial time spent indoors. This aspect is especially n [...]

2589 15821

Open Access Review

Herb-Drug Interactions in Oncology: A Clinical Up-Date

Received: 27 September 2018;  Published: 18 October 2019;  doi: 10.21926/obm.icm.1904060

Abstract

Phytotherapy, which is defined as the use of titrated herbal extracts in clinical practice, has been receiving increasing interest in the scientific community recently. In the present report, information regarding the most important mechanisms underlying the drug-drug interactions (DDI) and herb-drug interactions (HDI) has been discussed briefly. Furthermore, the best known and relevant interactions of Ginkgo biloba, Citrus paradisi (Grapefruit Juice), Silybum marianum (Milk Thistle), Hypericum perforatum (St. John [...]

2135 15805

Open Access Review

Neuropathology and Therapeutics Addressing Glaucoma, a Prevalent Retina-Optic Nerve-Brain Disease that Causes Eyesight Impairment and Blindness

Received: 24 January 2022;  Published: 22 March 2022;  doi: 10.21926/obm.neurobiol.2201116

Abstract

Glaucomatous optic neuropathy (GON) associated with different forms of glaucoma and chronic ocular hypertension (cOHT) is characterized by progressive loss of retinal ganglion cells and their axons in the optic nerves that project to the brain to transmit visual information. The resultant thinning of the optic nerves cause loss of peripheral vision, which if not halted or slowed, can lead to irreversible blindness. Whilst the precise triggering insult(s) for the primary open angle glaucoma (POAG), the most prevalen [...]

2225 15790

Open Access Review

The Role of Cognition in Balance Control

Received: 14 September 2023;  Published: 17 February 2024;  doi: 10.21926/obm.neurobiol.2401211

Abstract

Balance is the ability to move and/or preserve a particular position while not falling under external force. Human balance is a complex process of integration and coordination of the sensory, motor, and biomechanical components, which is influenced by intrinsic and exogenous factors. One inherent factor that is hypothesized to have an impact on balance is cognition. However, studies about cognition's role in balance control are still limited, and study literature is needed to gain a better understanding. Cognition [...]

2535 15775

Open Access Original Research

Zero-Emission Geothermal Power Generation: Experimental Study on Carbonate Mineralization through CO2-Andesitic Pyroclastic Rock Interaction at Oku-Aizu Geothermal Plant

Received: 27 November 2019;  Published: 12 February 2020;  doi: 10.21926/jept.2001002

Abstract

In order to achieve advancement in zero-emission geothermal power generation for fixing the CO2 in the geothermal fluids to the carbonate minerals after binary power generation and reinjection of the fluid into the reservoir, batch-type experiments and geochemical simulations of CO2-andesitic pyroclastic rock interaction (tuff from Oku-Aizu geothermal area) were performed at 150 °C with and without CO2 gas for 15 days. Despite the low Ca content (0.9% wt.%) in the rock, the Ca2+ concentrations in the solutions [...]

4318 15773

Open Access Review

From Light to Sound: Photoacoustic and Ultrasound Imaging in Fundamental Research of Alzheimer’s Disease

Received: 24 October 2019;  Published: 30 April 2020;  doi: 10.21926/obm.neurobiol.2002056

Abstract

Alzheimer’s disease (AD) causes severe cognitive dysfunction and has long been studied for the underlining physiological and pathological mechanisms. Several biomedical imaging modalities have been applied, including MRI, PET, and high-resolution optical microscopy, for research purposes. However, there is still a strong need for imaging tools that can provide high spatiotemporal resolutions with relatively deep penetration to enhance our understanding of AD pathology and monitor treatment progress in fundamental r [...]

2515 15766

Open Access Research Article

Enhancement of Fischer-Tropsch Synthesis by Periodical Draining of the Wax-Filled Pores of a Cobalt Catalyst by Hydrogenolysis

Received: 27 September 2022;  Published: 03 January 2023;  doi: 10.21926/cr.2301001

Abstract

Fischer-Tropsch reactors operated in a steady state suffer from a low pore effectiveness factor and a high methane selectivity caused by internal mass transfer limitations due to the accumulation of long-chain hydrocarbons inside the catalyst pores. Therefore, an alternating process switching between Fischer-Tropsch synthesis (FTS) and drainage of the pores by hydrogenolysis is proposed. The periodical cracking of the accumulated waxes within the (partially) filled pores, realized by a switch from syngas (H2, CO) t [...]

2213 15745

Open Access Review

A Review on the Application of the MPC Technology in Wind Power Control of Wind Farms

Received: 23 April 2021;  Published: 15 July 2021;  doi: 10.21926/jept.2103033

Abstract

Due to the uncertainty and volatility of wind speed, its natural output power also exhibits strong volatility. In order to avoid the negative effects of the excessive fluctuation of the output power of wind turbines in the wind farm and the power grid, it is very important to accurately predict and reasonably plan and control the output power of the wind farm. Model predictive control (MPC) is a type of advanced control method that can deal with a multi-input multi-output nonlinear system. Compared to the tradition [...]

2361 15737

Open Access Review

Trisomy 14 Mosaicism Including Concomitant Uniparental Disomy: Population Frequency, Cytogenetic Profile, Sex Ratio, Maternal Age and Obstetric History

Received: 02 May 2022;  Published: 05 September 2022;  doi: 10.21926/obm.genet.2203162

Abstract

Mosaicism for trisomy of chromosome 14 (T14) is a very rare chromosomal disease in liveborn patients. Since the 1970s, when the first patients with mosaicism for T14 were reported, a number of studies on the clinical manifestations of this abnormality have been published. No information on epidemiological parameters was known except for the rarity of the disease and its predominance among female carriers. This was the first systematic review of published cases of mosaic T14 that addressed some epidemiological aspec [...]

2610 15725

Open Access Review

Epigenetic Regulation by Androgen Receptor in Prostate Cancer

Received: 26 May 2018;  Published: 02 November 2018;  doi: 10.21926/obm.genet.1804047

Abstract

Prostate cancer is the most common cancer among men in the world. Androgen receptor (AR), acting as a nuclear receptor, facilitates ligand-dependent transcriptional activation in the nucleus. Androgen deprivation therapy (ADT) is used for the treatment of advanced prostate cancer because androgen and AR signaling drive prostate tumor growth and anti-apoptotic function. Resistance to ADT in most tumors develops quickly; thus, AR continues to be active in relapsed tumors called castration-resistant prostate cancer (C [...]

2062 15705

Open Access Research Article

Assessment of AAR and Sulfate Attack on Wadi Gravel Concrete after 4 Years in Service

Received: 18 April 2021;  Published: 26 September 2021;  doi: 10.21926/rpm.2103038

Abstract

Wadi gravel is a local aggregate in Qatar that could contribute to enhanced sustainability by replacing expensive imported gabbro. The material needs to be processed before use to reduce sulfate content to acceptable levels. The paper presents the performance assessment of three full-scale buildings, variously made with 50% and 100% Wadi gravel and conventional gabbro concretes. Site monitoring up to four years in service demonstrated the strength development with age and resistance to the aggressive exposure condi [...]

1654 15698

Open Access Original Research

TTF-1-Expressing Supratentorial Embryonal Tumors (PNET): A Clinicopathologic Study of Two Cases and Literature Review of TTF-1-Positive Primary Brain Tumors

Received: 07 October 2018;  Published: 14 November 2018;  doi: 10.21926/obm.neurobiol.1804016

Abstract

Thyroid transcription factor 1 (TTF-1) is a nuclear polypeptide and a tissue-restricted member of the homeobox protein family that, when attached to DNA, plays a crucial role in regulating the expression of select genes during early embryonic development of the thyroid, lung, and brain. As often happens, the initial enthusiasm for the diagnostic value of TTF-1 as a selective immunohistochemical marker of lung and thyroid tumors began to dwindle, due to its detection in tumors arising from other organs. TTF-1-expres [...]

1819 15685

Open Access Review

Peripheral Nerve Dysfunction after Spinal Cord Injury

Received: 02 October 2020;  Published: 29 December 2020;  doi: 10.21926/obm.neurobiol.2004075

Abstract

Spinal cord injury (SCI) leads to an immediate loss of sensory and motor function below the level of injury mostly affecting people in the prime of life. In addition to the primary injury there is accumulating neurophysiological and histological evidence of dysfunction in the peripheral nerves, not related to direct damage from the primary injury, which exacerbates muscle wasting, and contributes to further functional loss and poor recovery. Among the potential contributing factors are systemic inflammation, and mo [...]

2311 15677

Open Access Review

Hypnosis for Resilience

Received: 04 February 2020;  Published: 08 July 2020;  doi: 10.21926/obm.icm.2003032

Abstract

The topic of resilience is of paramount importance. Although the term resilience was coined in the fields of physics and engineering, its use has spread to the fields of social sciences, biology, psychology, and psychiatry, as well as to the industry. Moreover, the term is now endowed with a wide range of meanings. The topic of resilience plays a central role in all critical life events. It is of paramount importance in medicine as well as in psychology and psychotherapy, where it is involved in both psychiatric di [...]

2568 15671

Open Access Research Article

Architecture as Habitat: Enhancing Urban Ecosystem Services Using Building Envelopes

Received: 13 August 2021;  Published: 09 November 2021;  doi: 10.21926/aeer.2104029

Abstract

The practice of reconciliation ecology in urban environments relies heavily on urban green space as the primary source of vegetated habitat in cities. However, most cities lack the quantity, connectivity, and accessibility of green space needed to provide essential ecosystem services for the health, well-being, and resilience of human and non-human species. In reaction to urban densification and the increasing frequency and severity of climate change impacts, this study argues that architecture could strategically [...]

1459 15663

Open Access Technical Note

From Food to Foot: The Energy and Carbon Flows of the Human Body at Walking and Cycling

Received: 10 March 2022;  Published: 18 July 2022;  doi: 10.21926/jept.2203025

Abstract

The carbon footprint of motorized transport modes per unit length traveled encompasses the unit share of the vehicle lifetime emissions, that of the transport infrastructure, and those of the motor energy, considered both from “well to tank” and from “tank to wheel”. In the active modes of transport, i.e., walking and cycling, the counterpart of motor energy is human energy, which is associated with two kinds of carbon flows: the carbon footprint of food intake, – which we call the Food to Body component – and the [...]

2289 15639

Open Access Review

Histone O-GlcNAcylation and Potential Biological Functions

Received: 05 July 2018;  Published: 17 September 2018;  doi: 10.21926/obm.genet.1803036

Abstract

Histone modifications play an important role in the control of DNA-based processes by altering the structure and function of chromatin. O-linked N-acetylglucosamine (O-GlcNAc) modification is a form of post-translational modification of proteins that affects the serine (Ser)/threonine (Thr) residues. This process is controlled by a single pair of enzymes, i.e. O-GlcNAc transferase (OGT) and O-GlcNAcase (OGA). Recent evidence indicates the existence of O-GlcNAc modification of histones, with 16 histone O-GlcNAc site [...]

2548 15627

Open Access Communication

Neuronal Coherence Agent for Shared Intentionality: A Hypothesis of Neurobiological Processes Occurring during Social Interaction

Received: 02 October 2021;  Published: 29 December 2021;  doi: 10.21926/obm.neurobiol.2104113

Abstract

The present interdisciplinary study discusses the physical foundations of the neurobiological processes occurring during social interaction. The review of the literature establishes the difference between Intentionality and Intention, thereby proposing the theoretical basis of Shared Intentionality in humans. According to the present study, Shared Intentionality in humans (Goal-directed coherence of biological systems), which is the ability among social organisms to instantly select just one stimulus for the entire [...]

1813 15613

Open Access Short Review

The Effects of Aquatic Exercise on Cognitive Function: Systematic Review

Received: 07 February 2019;  Published: 21 March 2019;  doi: 10.21926/obm.icm.1901018

Abstract

The objective of this brief systematic review was to examine the effects of aquatic exercise on cognitive function. Studies were identified using electronic databases, including PubMed, PsychInfo, Sports Discus and Google Scholar. In total, 13 articles met the inclusionary criteria. Among the 13 studies, all 13 demonstrated beneficial cognitive effects from exercise. This included chronic aquatic exercise-induced improvements in global cognition, executive function, attention, learning and memory, cognitively-relat [...]

3223 15587

Open Access Original Research

About Non-relativistic Quantum Mechanics and Electromagnetism

Received: 21 October 2022;  Published: 08 December 2022;  doi: 10.21926/rpm.2204027

Abstract

We describe here the coherent formulation of electromagnetism in the non-relativistic quantum-mechanical many-body theory of interacting charged particles. We use the mathematical frame of the field theory and its quantization in the spirit of the quantum electrodynamics (QED). This is necessary because a manifold of misinterpretations emerged especially regarding the magnetic field and gauge invariance. The situation was determined by the historical development of quantum mechanics, starting from the Schrödinger e [...]

6707 15563

Open Access Review

Diagnosis and Therapy of Atrial Fibrillation in Geriatric Patients

Received: 16 January 2021;  Published: 28 July 2021;  doi: 10.21926/obm.geriatr.2103178

Abstract

Atrial fibrillation is very common in most old patients who need an adapted therapy due to their comorbidities. Before initiating an antiarrhythmic therapy, possible adverse effects, especially iatrogenic proarrhythmia, and extracardiac side-effects, must be considered. In geriatric patients with atrial fibrillation, heart rate control is the most frequent therapy. Oral anticoagulation plays a vital role in the therapy, but anticoagulation in old patients, who had a bleeding or stroke event, is challenging. Availab [...]

1693 15550

Open Access Review

Phytoremediation: A Sustainable Approach to Combat Soil Salinity

Received: 14 March 2024;  Published: 12 June 2024;  doi: 10.21926/aeer.2402015

Abstract

Soil salinization is a significantconstraint affecting the productivity of agricultural land worldwide. This led to the abandoning of the production of farmcrops on colossalland. Soil salinity inversely affects seed germination and plant growth and influences the plant’s biological activities like photosynthesis, respiration, plant metabolism, enzymatic activities, hormone regulation, etc. Therefore, efforts are being made to bring the saline soil under cultivation by improving itthrough a proper drainage sys [...]

1939 15532

Open Access Research Article

Plant Breeding Integrated with Genomic-Enabled Prediction

Received: 09 June 2021;  Published: 15 September 2021;  doi: 10.21926/obm.genet.2103137

Abstract

Plant breeding programs have used conventional breeding methods, such as hybridization, induced mutations, and other methods to manipulate the plant genome within the species' natural genetic boundaries to improve crop varieties. However, repeatedly using conventional breeding methods might lead to the erosion of the gene reservoir, thereby rendering crops vulnerable to environmental stresses and hampering future progress in crop production, food and nutritional security, and socio-economic benefits. Integrating in [...]

1706 15529

Open Access Review

Viral Infections in Allogeneic Hematopoietic Stem Cell Transplant Recipients: Literature Review

Received: 25 June 2019;  Published: 26 August 2019;  doi: 10.21926/obm.transplant.1903081

Abstract

Hematopoietic stem cell transplant (HSCT) recipients are at an increased risk of bacterial, viral, fungal and parasitic infections. Past exposures to infections, the degree of immunosuppression, prolonged neutropenia and presence of graft versus host disease (GVHD) are some of the factors which make HSCT recipients more susceptible to infections. Viral infections have emerged as a major challenge causing high morbidity and mortality in stem cell transplant recipients. Myeloablative conditioning regimens and GVHD pr [...]

2154 15525

Open Access Original Research

Cradle-to-Grave Life-Cycle Assessment of Cellulosic Fiberboard

Received: 24 August 2021;  Published: 21 December 2021;  doi: 10.21926/rpm.2104049

Abstract

According to the United Nations Environment Programme (UNEP), the construction and operation of buildings accounted for nearly 38% of total global energy-related CO2 emissions in 2019. The construction sector has been striving to use more low-carbon footprint building products to mitigate climate change and enhance environmentally preferable purchasing. Over the last several decades, there has been substantial growth in engineered wood products for the construction industry. To assess these products used in constru [...]

1612 15518

Open Access Opinion

A Potential Role of Coenzyme Q10 Deficiency in Severe SARS-CoV2 Infection

Received: 01 August 2020;  Published: 26 October 2020;  doi: 10.21926/obm.icm.2004042

Abstract

There is a dramatic need for extensive research into the predictors of severe infection with SARS-CoV2 and therapeutic options for infected people. People who suffer from severe illness and higher mortality display a pattern of having specific co-morbidities (diabetes, obesity, hypertension) and are of higher age. Recent research has described methods of viral entry via receptors (ACE2, TMPRSS2) and the hyper-inflammatory state often associated with severe illness (increase in interleukins, increase in TNF-alpha). [...]

2308 15516

Open Access Review

Case Reports of Patients Using Homeopathy in Which Complete Healing Was Observed: A Literature Review

Received: 20 June 2024;  Published: 12 October 2024;  doi: 10.21926/obm.icm.2404058

Abstract

To systematically review the literature for cases using homeopathy in which complete healing was observed. Scielo, Pubmed, CINAHL, and Embase databases were systematically screened for case reports and series of patients successfully cured by homeopathy between 1966 and August 2022. Language limitation was not used. Forty-nine articles, comprising 191 patients, were depicted. Most of them had dermatological conditions (12 papers, 71 patients), followed by infectious (7 papers, 31 patients), neuropsychiatric (10 pub [...]

1396 15501

Open Access Research Article

Chair Fitness Program for Improved Strength and Physical Function for Older Adults: A Pilot Comparative Effectiveness Study

Received: 05 July 2023;  Published: 12 September 2023;  doi: 10.21926/rpn.2303016

Abstract

Within the US, people are experiencing longer life expectancy, yet these extended lifespans have not necessarily translated into years living in good health. Musculoskeletal degenerative diseases are particularly prevalent amongst older adults. Research shows that regular resistance exercise carries preventive health benefits to combat these conditions. This study evaluated the impact of an innovative hand-held device (OYO) on the physical function of older adults compared to a traditional chair fitness program (CF [...]

1524 15496

TOP