Table of Content

Open Access Original Research

Patient-Reported Outcome Measures (PROMs) in Neurology for Web 3.0 and mHealth: A Conceptual Framework

Received: 02 June 2023;  Published: 09 January 2024;  doi: 10.21926/obm.neurobiol.2401206

Abstract

According to 2019 WHO data, neurological conditions contribute to 1503.39 disability-adjusted life years (DALYs) per 100,000 population. Approximately 57% of office-based physicians use EHR systems and the natural place to incorporate standardized ePRO is into EHR. However, implementing patient-reported outcomes (PROs) for neurological conditions is challenging because many patients are elderly, have comorbidities, and experience cognitive impairment. As healthcare digitization increases, we propose a framework for [...]

1304 7413

Open Access Original Research

Historical Evolution and Scenarios Up to 2050 of Heating Energy Consumption and CO2 Emissions of Residential Buildings in Vienna

Received: 24 June 2022;  Published: 27 September 2022;  doi: 10.21926/jept.2203030

Abstract

Today, the building sector poses a major problem concerning fossil fuel energy consumption and the corresponding emissions of local pollutants and global greenhouse gases (GHG). In addition, an increasing number of people are living in urban areas, and it is becoming challenging to provide the necessary living space and energy for heating in fast-growing cities. Currently, urban areas host approximately 50 % of the global population and generate 70 % of GHG. The core objective of this study is to analyze the histor [...]

1303 9337

Open Access Research Article

Effects of Chemical Stabilisation of Eggshells-Lime and Fly-Ash-Cement on the Structural Strength of Subgrade Soil in Rural Roads

Received: 15 May 2022;  Published: 04 August 2022;  doi: 10.21926/rpm.2203013

Abstract

This study examines the chemical compositions of eggshell powder (ESP) and lime as the soil stabilisers and compared with the compositions of cement and fly-ash to understand the optimal distribution of chemical stabilisers maximising the bearing capacity and structural integrity of subgrade soil. The different proportions of eggshell powder (ESP) (2%, 4%, 6% and 8% of total soil mass) were mixed with a fixed proportion of lime (6% of total soil mass) to analyse the optimum proportion of eggshell maximising the soi [...]

1302 11384

Open Access Research Article

Molecular and in Silico Analysis of MEFV Variants in Familial Mediterranean Fever Patients in Southwest Iran

Received: 11 October 2022;  Published: 12 May 2023;  doi: 10.21926/obm.genet.2302181

Abstract

Familial Mediterranean Fever (FMF) is classified as an autoinflammatory genetic disease inherited by mutations in MEFV. These mutations can affect the dysregulation of inflammatory processes in the human body and lead to fever and pain in the chest and abdomen. Many known missense mutations in MEFV are linked to FMF disease. Mutations in MEFV in most cases are located on the short arm of chromosome 16 and can impair the function of the pyrin protein. In this research, we aimed to examine the entire exons of MEFV fo [...]

1301 8786

Open Access Original Research

Examining the Role Between Social Antecedents and Depression among LGBTQ+ Older Adults Eligible for Low-Income Housing

Received: 28 July 2023;  Published: 15 December 2023;  doi: 10.21926/obm.geriatr.2304261

Abstract

Housing is one of the top four most needed services for LGBTQ+ older adults, and this study focuses on the intersection of depression and social antecedents among LGBTQ+ older adults eligible for low-income housing. To explore social antecedents (i.e., demographics, early events, later events, social integration, and stressors) associated with screening positive for depression among low-income LGBTQ+ older adults from two cities in the Western United States. A cross-sectional study was conducted with LGBTQ+ older a [...]

1301 7471

Open Access Case Report

The Low FODMAP Diet for Children with Inflammatory Bowel Disease and Overlapping Functional Gastrointestinal Symptoms – a Case Series

Received: 11 February 2023;  Published: 29 June 2023;  doi: 10.21926/rpn.2302009

Abstract

The low FODMAP diet (LFD) is a dietary intervention developed for and used particularly for the management of functional GI symptoms (FGIS) in adults with irritable bowel syndrome (IBS). It has also been proposed to improve coincident functional gut symptoms in adults with inflammatory bowel disease (IBD). This report describes the outcomes of the LFD in a series of children with IBD with concurrent FGIS. This study included children aged between 7-14 years with quiescent IBD and overlapping FGIS. All participants [...]

1301 12831

Open Access Original Research

Conservation Prioritization of Ecologically Susceptible Zones at Disaggregated Levels

Received: 29 December 2021;  Published: 22 April 2022;  doi: 10.21926/aeer.2202014

Abstract

Ecologically susceptible zones (ESZs) are endowed with the distinct bio, geo, climatic, hydrological, and ecological integrity that sustain natural resources to support the livelihood of dependent populations. However, globalization and consequent anthropogenic activities have led to the erosion of the natural resource base and enhanced the levels of pollutants, triggering global environmental change, evident from changes in the climate. Alterations in the structure and the ecological integrity of ESZs may lead to [...]

1300 10149

Open Access Review

Do Antioxidants Extend Longevity in Invertebrate and Vertebrate Animals?

Received: 09 November 2022;  Published: 07 March 2023;  doi: 10.21926/obm.geriatr.2301226

Abstract

In the 1950’s Denham Harman proposed the Free Radical Theory of Aging whereby species lifespan and individual longevities are the consequence of free radical driven damage to biomolecules. This led to decades of research to ascertain the effect of altered antioxidant defense systems on aging and mortality in an array of species using reverse genetics and dietary manipulation. Within invertebrates, the data generally support the Free Radical Theory in that overexpression of antioxidant enzymes or dietary supplementa [...]

1300 9135

Open Access Review

Clinical Practice Guidelines About Screening for Disruptive Behavior Problems at Well-Child Visits: A Rapid Review of the Literature on the Accuracy of Parents’ Behavioral Concerns

Received: 08 March 2022;  Published: 03 August 2022;  doi: 10.21926/obm.icm.2203031

Abstract

The current recommendations of the Canadian Paediatric Society about monitoring children’s disruptive behaviors at well-child visits call for screening if behavioral concerns are being raised by parents. But do parents’ concerns about their child’s behavior constitute a reliable means for primary care providers (PCPs) to decide either in favor or against screening? We conducted a rapid systematic review of the literature by identifying documents that cited the landmark study by Glascoe and her col [...]

1300 7664

Open Access Research Article

Evaluation of a Virtual Compassionate Living Group for Patients with Chronic Pain

Received: 26 May 2022;  Published: 14 November 2022;  doi: 10.21926/obm.icm.2204050

Abstract

Chronic pain affects around 28 million people in the UK. Those living with chronic pain can frequently experience internalised self-stigma and negative self-evaluations as a result of the pain itself and due to difficult life experiences. Previous research has found Compassion Focused Therapy to be effective for people living with long term health conditions like chronic pain. The current study sought to evaluate a routine Virtual Compassionate Living Group for patients with chronic pain on the measures of self-com [...]

1300 7781

Open Access Research Article

Using SIRES to Enhance Resilience in Remote & Rural Communities

Received: 29 August 2021;  Published: 21 January 2022;  doi: 10.21926/jept.2201006

Abstract

Rural and remote communities are more vulnerable to damage caused by extreme events as compared to urban areas. Natural disasters can disrupt basic supplies such as domestic water supply and cooking needs in addition to electricity outages. The recognition of the interlinked nature of food, water and energy has gained momentum over the past few years. Smart Integrated Renewable Energy System (SIRES) has been proposed to handle basic needs such as cooking, domestic and irrigation water supply, and electricity to rem [...]

1299 9375

Open Access Perspective

Responsible Materials Stewardship: Rethinking Waste Management Globally in Consideration of Social and Ecological Externalities and Increasing Waste Generation

Received: 04 September 2023;  Published: 04 January 2024;  doi: 10.21926/aeer.2401002

Abstract

Unsustainable material extraction, use and disposal - the ‘take-make-waste’ model - places communities globally in a state of social inequalities and environmental conflict (the slow violence of polluting the air, water, and soil we all depend). Current waste management practices are designed for efficiency of disposal but do not address increasing waste generation and waste externalities. The present global waste situation is magnified by exponential increases in plastic production; misconceptions of recycling; an [...]

1298 8664

Open Access Original Research

Cell Level- Modeling of Aging and Rejuvenation

Received: 14 April 2023;  Published: 22 December 2023;  doi: 10.21926/obm.geriatr.2304263

Abstract

Understanding processes related to human aging and rejuvenation relies on experimental data and advanced models operating at different levels. There are several existing conceptual and specific modeling approaches. However, one of the existing tasks is compiling generic models linking properties at cell and cell-element levels to properties at systemic levels - tissue, organ, and whole body. One of the critical issues in the relevant models is the enormity of interacting components at the cell and sub-cell levels n [...]

1298 8060

Open Access Research Article

Assessing Burnout and Well-Being in Higher Education Health Science Faculty

Received: 25 October 2022;  Published: 14 February 2023;  doi: 10.21926/obm.icm.2301014

Abstract

This study aimed to examine and compare the extent of burnout among health science faculty at a higher education institution and their self-reported perception of well-being during the COVID-19 pandemic. The design of the study was cross-sectional, descriptive survey research. An electronic questionnaire was developed to measure the constructs of burnout and well-being. Validated instruments used in the survey included the Oldenburg Burnout Inventory (OLBI) and the World Health Organization-5 Well-being Index. The [...]

1298 12769

Open Access Original Research

Hydrological Effects of Spatial Harvest Patterns in a Small Catchment Covered by Fast-Growing Plantations in the Neotropics

Received: 07 October 2022;  Published: 21 February 2023;  doi: 10.21926/aeer.2301022

Abstract

Eucalyptus forests are expanding worldwide and concerns exist about their impact on water resources. There is a lack of information about the hydrological effects of spatial harvest patterns in terms of their effects on streamflow. In this paper, we examined harvest amount and hillslope position effects on flow indices (Q70; Q50 and Q10) and water yield in a small catchment covered with a fast-growing Eucalyptus plantation. To do that, we used the Gridded Surface Subsurface Hydrologic Analysis (GSSHA), a physical-b [...]

1297 6950

Open Access Review

Environmental Land Management and Assessment, in the Context of Resource and Climate-Related Conflict

Received: 23 November 2022;  Published: 12 June 2023;  doi: 10.21926/aeer.2302036

Abstract

This paper reviews the growing importance of satellite imagery to provide Normalized Difference Vegetative Index (NDVI) maps, relevant to environmental land management assessment, in the context of resource and climate-related conflict based upon our own humanitarian project-related support. Near real-time space-based monitoring benefits land assessment, human rights observers, and Non-Governmental Organizations (NGOs), in the presence of unstable regimes or socio-economic upheaval. Access to areas to validate clai [...]

1297 7414

Open Access Perspective

Leveraging Existing Abilities in Dementia (LEAD™): Changing the Way Rehabilitation Professionals Care for Persons Living with Dementia

Received: 08 December 2023;  Published: 03 April 2024;  doi: 10.21926/obm.geriatr.2402275

Abstract

Latest estimates indicate that 5-7% of the population are living with Alzheimer’s disease and related dementias worldwide with a doubling in incidence expected every 20 years. Rehabilitation professionals are challenged with the complex needs of these patients. It is commonly thought that patients with dementia do not benefit from rehabilitation because of cognitive decline, behaviors, lack of communication, or difficulties in learning; however, current literature indicates this is not accurate. With proper knowled [...]

1297 7774

Open Access Review

Non-Celiac Gluten Sensitivity in Children: Controversial Role of Gluten and Diagnostic Enigma

Received: 07 July 2021;  Published: 22 July 2021;  doi: 10.21926/obm.hg.2103059

Abstract

Non-celiac gluten sensitivity (NCGS) is a debatable condition that affects less than 6% of children. The absence of specific diagnostic markers and standardized diagnostic procedures make the diagnosis of NCGS challenging, covering patients with different and varied symptoms. Generally, the parents of small and younger children introduce a gluten-free diet (GFD) based on their personal experiences and expectations. Additionally, a “fad component” exists, contributing to the recent rise in the popularity of GFD. Thu [...]

1297 5737

Open Access Original Research

Integration between Geriatric Oncology and Palliative Care: A Single Center Experience for Hospitalized Older Patients with Cancer

Received: 26 October 2022;  Published: 27 March 2023;  doi: 10.21926/obm.geriatr.2301230

Abstract

Comprehensive Geriatric Assessment (CGA) is utilized to plan social and health care of the elderly and to complete the diagnostic-therapeutic choice of oncologist also considering early integration with palliative care. Cancer patients (pts) hospitalized aged ≥70 years were screened by the G8 questionnaire to define if necessary CGA. CGA identified: fit, unfit and frail pts. We screened 95 pts by G8 and 93 (98%) were at risk. Pts at risk, evaluated by CGA resulted: 3 fit, 45 unfit and 45 frail. 3 fit pts received s [...]

1296 7624

Open Access Review

Minimally Invasive Treatments for Glioblastoma: A Review of Current and Emerging Surgical Technologies

Received: 22 February 2022;  Published: 03 March 2023;  doi: 10.21926/obm.neurobiol.2301160

Abstract

Glioblastoma (GBM) is malignant, primary intracranial neoplasm associated with poor outcomes. Maximal, safe cytoreduction remains an important component of effective treatment for patients with this disease; however, some patients are not candidates for resection due to comorbid status, tumor location, or other factors. In this review, we aimed to describe minimally invasive surgical techniques that are emerging as important tools for improving safety and efficiency in GBM cytoreduction, including for patients with [...]

1296 10373

Open Access Review

Economic Considerations in Using HCV and HIV Positive Donors for Kidney Transplant

Received: 29 August 2021;  Published: 18 October 2021;  doi: 10.21926/obm.transplant.2104154

Abstract

End Stage Renal Disease is becoming more prevalent in the United States of America, with demand for kidney transplant exceeding the available organ supply. A novel method to increase the donor pool has been to consider transplanting organs from deceased patients who have had Hepatitis C Virus (HCV) or Human Immunodeficiency Virus (HIV) infections. Transplants with HCV infected kidneys are becoming more prevalent, due to increased organ supply due to increased mortality from injection opioid use. Similarly, deceased [...]

1296 9498

Open Access Editorial

Anemia during Direct-Acting Antiviral Regimens in Kidney Transplant Recipients with Hepatitis C

Received: 18 October 2017;  Published: 29 October 2017;  doi: 10.21926/obm.hg.1704005

Abstract

(This is review and no abstract)

1295 5434

Open Access Review

Classical and Non-Classical Neural Communications

Received: 13 April 2023;  Published: 27 August 2023;  doi: 10.21926/obm.neurobiol.2303181

Abstract

This review was constructed to show how the connectome has evolved in motor command systems from simple command elements to complex systems of neurons utilizing parallel distributed processing and the possibility of quantum entanglement between groups of neurons. Scientific and medical interest in neural pathways and their connections have driven neuroscience and brain research for many decades so that specific systems and their feedback loops have been considered in detail. We review motor command systems in inver [...]

1295 7875

Open Access Original Research

The Effect of Oxygen-containing Additives in Feedstock on the Performance of the Catalytic Cracking Process

Received: 28 July 2022;  Published: 26 October 2022;  doi: 10.21926/cr.2204037

Abstract

In this study, we found that adding catalytic cracking feedstock, vacuum gas oil, and naphthenic acids in the amount of 0.005–0.0075% vol. increased the liquid target fractions, i.e., gasoline and light gas oil. The decrease in the yield of hydrocarbon gas at a practically constant degree of conversion of the raw material indicated a small proportion of the reactions of re-cracking of the resulting products. This also indicated the resource-saving nature of the process, allowing a larger amount of gasoline fraction [...]

1294 7502

Open Access Editorial

Is There Evidence of Toxicity in Long-Term Photobiomodulation?

Received: 18 September 2022;  Published: 19 September 2022;  doi: 10.21926/obm.icm.2203042

Abstract

This editorial briefly discusses the issue of potential toxicity in the case of long-term photobiomodulation (PBM). Scientific articles from PubMed, Google Scholar, and the China National Knowledge Infrastructure were included in a heterogeneous search. There have been very few studies on the long-term effects of PBM, as well as its potential toxicity. There is no evidence that PBM is toxic when used at therapeutic or imaging doses. There are no such concerns with intracranial PBM application (e.g., optical fiber) [...]

1293 8415

Open Access Original Research

Impacts of Carbon Capture and Storage (CCS) Technology on the Sustainability of Coal-Based Power Generation Pathways

Received: 16 November 2024;  Published: 10 March 2025;  doi: 10.21926/rpse.2501003

Abstract

Carbon capture and storage (CCS) technology mitigates greenhouse gas (GHG) emissions. However, comprehensive studies assessing the sustainability of coal-based power generation (CBPG) with CCS remain limited. This study focuses on developing comparative sustainability indicators across the entire life cycle of CBPG integrated with CCS technology. Sixty-six pathways were analyzed after establishing five sustainability indicators for each. These indicators were standardized per megawatt-hour (MWh) of energy, encompas [...]

1293 6794

Open Access Research Article

Evaluation of the Performance of Vital Services in Urban Crisis Management

Received: 08 October 2022;  Published: 26 December 2022;  doi: 10.21926/aeer.2204057

Abstract

Crisis management assessment and planning include many components. One of the essential elements is the review and analysis of the structure of the existing situation and the performance of Vital services in the face of critical cases. During the occurrence of natural disasters, the issue of crisis management is crucial in order to reduce the damages caused by the crisis. One thing that reduces the damages is the correct and timely access of critical relief centers such as fire departments, emergency, police force, [...]

1292 8203

Open Access Original Research

The Identification 5S nrDNA Unit Classes in Genera of Plants and Selected Non-Vertebrate Animals and Their Potential for the Study of Species Relationships

Received: 07 January 2022;  Published: 24 April 2022;  doi: 10.21926/obm.genet.2202152

Abstract

We have investigated the utility of the 5S nrDNA, a conserved, multicopy gene family organized into tandem repeats as a tool for genetic analyses in a wide variety of genera. Previous work in the Triticeae (Poaceae) demonstrated that the prior identification of unit classes based upon the 5S nrDNA NTS, greatly facilitates analysis. We investigated the potential of defining unit classes in other plant genera and several animal genera as a step towards future phylogenetic analyses. Our results demonstrate that in in [...]

1292 7998

Open Access Original Research

Mapping, Meeting and Modulating Stress and Emotion: Combining Mindfulness and the Workable Ranges Model

Received: 05 August 2022;  Published: 22 December 2022;  doi: 10.21926/obm.icm.2204055

Abstract

This article examines the practice of combining explorations of regulated and dysregulated states through the Workable Ranges Model (WRM) with the skills and qualities taught in Mindfulness-Based Stress Reduction (MBSR). MBSR was designed to help participants to self-regulate stress. Didactic teaching about stress reactivity is part of the curriculum and may contribute to positive outcomes. A practice-based embodied methodology utilised mindful inquiry in research methods. Seven graduates of MBSR courses that inclu [...]

1292 8313

Open Access Original Research

Interactive and Deep Learning-Powered EEG-BCI for Wrist Rehabilitation: A Game-based Prototype Study

Received: 14 August 2025;  Published: 24 September 2025;  doi: 10.21926/obm.neurobiol.2503302

Abstract

Motor deficits induced by neurological disorders impose a severe impact on activities of daily life. Conventional rehabilitation practices necessitate ongoing clinical supervision, which is costly and inaccessible. EEG-based brain-computer interface (BCI) systems offer a viable solution by facilitating neurorehabilitation through the direct interpretation of brain signals. Nonetheless, current systems are confronted with issues of real-time control, portability, and classification precision. The paper describes a n [...]

1292 7109

Open Access Original Research

Solubility of Dental Ceramics in Electric Fields

Received: 21 April 2022;  Published: 15 June 2022;  doi: 10.21926/rpm.2202012

Abstract

Combining dental ceramics with other prosthetic metallic restorations might release metal ions, thus affecting the oral tissues of the patients. In this study, we evaluated the electrochemical solubility of various dental ceramics in a galvanic experimental setup in vitro. Smooth and rough feldspathic and zirconium dioxide ceramics (at pH 5.5 and pH 3.0) were exposed to an electric field. Calcium, barium, and zirconium were selected as parameters to determine the solubility of both types of ceramic materials. Among [...]

1292 8326

Open Access Review

Fall Prevention Knowledge and Attitude Tests-Surveys Used by Staff and Nurses: A Systematic Review of Current Literature

Received: 01 February 2025;  Published: 26 June 2025;  doi: 10.21926/obm.geriatr.2502317

Abstract

Falls are a serious global public health issue affecting individuals of all ages, resulting in serious injuries, fatalities, and extended hospital stays. While knowledge and attitude of healthcare staff toward fall prevention are understood to impact patient safety, less well known are the type and content of fall prevention surveys used to identify nurses’ knowledge of fall prevention. Until now, no study has systematically reviewed the universe of existing tests, surveys, and programs used to assess fall pr [...]

1290 8952

Open Access Original Research

Evaluation of Bioactive Compounds Obtained from Ginkgo Biloba Against Crystal Structure of Myelin Oligodendrocyte Glycoprotein (MOG)

Received: 07 July 2023;  Published: 09 October 2023;  doi: 10.21926/obm.neurobiol.2304186

Abstract

Multiple Sclerosis (MS) spreads rapidly across the globe, causing almost 2.8 million cases worldwide. Many drugs and inhibitors, such as dronabinol and nabilone, have been used to treat MS, but there is no effective treatment for MS till now as these medications can cause severe side effects. So, we tested different compounds from Ginkgo biloba to inhibit the symptoms caused by MS as an herbal treatment. We targeted the Crystal structure of Myelin Oligodendrocyte Glycoprotein as it has shown some excellent results [...]

1290 8718

Open Access Short Review

Postoperative Cognitive Dysfunction and Virtual Reality for Cognitive Rehabilitation in Cardiac Surgery Patients: A Short Review

Received: 02 November 2023;  Published: 19 March 2024;  doi: 10.21926/obm.neurobiol.2401215

Abstract

Postoperative cognitive dysfunction (POCD) has been observed as a complication after cardiac surgery consistently. The ineffectiveness of current treatments for POCD is causing a search for non-invasive alternatives. The present review aims to consolidate the current understanding of how VR methods effectively facilitate the recovery of cognitive functioning in cardiac surgery patients. To obtain information about the effects of VR technology on cognitive functions, we investigated the PubMed, Scopus, and Web of Sc [...]

1290 5907

Open Access Original Research

Indoor Built Environments Attended by Primary School Children and Its Microbiology: A Cross-Project Study

Received: 10 March 2022;  Published: 24 August 2022;  doi: 10.21926/rpm.2203015

Abstract

Exposure to indoor pollutants may exert a significant effect on children health as they spend most of their time in enclosed environments. This research compared the association of biological concentrations with indoor characteristics and building materials in places where children spend significant time indoors. It was compared the results of two autonomous research projects conducted in Porto primary schools and households. Both the projects included a walkthrough inspection and biological measurements in indoor [...]

1290 8273

Open Access Review

Malignancy in the Lung Transplant Population

Received: 16 July 2017;  Published: 12 September 2017;  doi: 10.21926/obm.transplant.1703004

Abstract

The risk for developing a variety of malignancies is significantly elevated in the setting of lung transplantation. Malignancy remains among the three major causes of death in post-transplant recipients, and the relatively high risk of cancer development as well as metastatic aggression pose special threats to this population due to the need for continued immunosuppression. A variety of risks such as tobacco use and inflammatory lung diseases that led to the lung pathology prompting lung transplantation, in additio [...]

1290 9566

Open Access Review

Hereditary Pancreatitis – A Review of Current Concepts and Management

Received: 30 April 2019;  Published: 19 July 2019;  doi: 10.21926/obm.hg.1903028

Abstract

(1) Background: Hereditary Pancreatitis is a rare cause of acute pancreatitis. These patients usually present at a young age with recurrent episodes of acute pancreatitis that usually progresses to chronic pancreatitis with associated endocrine and exocrine failure. Hereditary pancreatitis also carries an increased lifetime risk of pancreatic adenocarcinoma. These high risk patients need early intervention where appropriate by specialist multidisciplinary teams and tailored long term management. (2) Methods [...]

1288 8162

Open Access Original Research

Quantum and Component Analysis of P3a and P3b from Auditory Single Trial ERPs Differentiates Borderline Personality Disorder from Schizophrenia

Received: 09 April 2023;  Published: 13 July 2023;  doi: 10.21926/obm.neurobiol.2303174

Abstract

Traditional approaches to EEG modelling use the methods of classical physics to reconstruct scalp potentials in terms of explicit physical models of cortical neuron ensembles. The principal difficulty with such approaches is that the multiplicity of cellular processes, with an intricate array of deterministic and random influencing factors, prevents the creation of consistent biophysical parameter sets. An original, empirically testable solution has been achieved in our previous studies by a radical departure from [...]

1287 7840

Open Access Review

Oxidative Stress in Cerebral Ischemia/Reperfusion Injury

Received: 02 May 2024;  Published: 07 August 2024;  doi: 10.21926/obm.neurobiol.2403239

Abstract

Oxidative stress in cerebral ischemia/reperfusion injury (CIRI) involves reactive oxygen and nitrogen species (ROS and RNS). Despite efficient antioxidant pathways in the brain, hypoxia triggers the production of oxygen free radicals and downregulates ATP, which leads to oxidative stress. Sources of free radicals during CIRI include Ca2+-dependent enzymes, phospholipid degradation and mitochondrial enlargement. Upon reperfusion, the abrupt increase of oxygen triggers a massive radical production via enzymes like xa [...]

1287 9625

Open Access Review

A Breath of Fresh Air - Lung Transplantation Has Come of Age

Received: 11 January 2023;  Published: 04 April 2023;  doi: 10.21926/obm.transplant.2302179

Abstract

A boundless spectrum of chronic lung diseases is said to effect over 500 million persons globally. Lung transplantation is a well-established therapeutic option for patients suffering from end-stage lung diseases, however waitlist mortality and primary graft failure remain major determinants as post-transplantation 5-year survival is just above 50 percent. Recent innovations in lung transplantation have been aimed at increasing organ availability, improving allograft quality, function, and longevity. Ex-vivo Lung P [...]

1287 8734

Open Access Original Research

How Involvement in COVID-19-Related Work Changed Nurses' Job Demands, Job Resources, and Their Associations with Burnout: Evidence from China 1

Received: 09 January 2023;  Published: 27 March 2023;  doi: 10.21926/obm.neurobiol.2301164

Abstract

China adopted a “Zero-COVID” policy for nearly three years, making Chinese healthcare workers constantly involved in COVID-19-related work. However, little is known about how involvement in COVID-19-related work shaped Chinese nurses’ burnout. This study explores how nurses’ job demands and job resources are associated with their burnout by considering high and low frequent involvements in COVID-19-related work in China. This study employed a cross-sessional design. Guided by Job Demands-Resources (JDR) model, we d [...]

1285 8545

Open Access Original Research

Donor Age and Ischemia Time Are Independent Factors Affecting Graft Survival after En Bloc Kidney Transplantation from Donors Less than Three Years of Age

Received: 13 January 2020;  Published: 13 May 2020;  doi: 10.21926/obm.transplant.2002109

Abstract

This study aimed to investigate the outcomes of transplantation from donors aged less than three years in a single-center consecutive series. A total of 52 en bloc kidney graft transplantations were performed. In 22 cases, organs were procured from donors aged less than one year (group 1). In 30 cases, the age of donors varied from one to three years (group 2). After transplantation, renal function and graft and patient survival were evaluated retrospectively. No significant difference was observed between the grou [...]

1285 8811

Open Access Original Research

Organic Structure-Directing Agent Free Synthesis of Mordenite with Seeds, Used as A Support for Mo Catalysts in the Transesterification of Soybean Oil

Received: 20 December 2022;  Published: 07 April 2023;  doi: 10.21926/cr.2302015

Abstract

This work prepared mordenite using seeds and without organic structure-directing agents (OSDAs). The Mo/Mordenite was prepared through wet impregnation and the catalysts’ performance was checked for transesterification of soybean oil with methanol. The mordenite zeolite was prepared through hydrothermal crystallization under static conditions with a molar composition of 6Na2O:Al2O3:30SiO2:780H2O. The catalyst samples were characterized crystallinity through X-ray diffraction, elemental composition by X-ray fluoresc [...]

1284 9457

Open Access Original Research

Operation of AC Microgrids with PV Panels’ Output Power Curtailment for Minimizing the Use of Energy Storage

Received: 21 January 2022;  Published: 07 March 2022;  doi: 10.21926/jept.2201008

Abstract

In this paper, a method for operating AC microgrids in both off-grid or standalone and grid-connected modes is proposed to minimize the use of energy storage by increasing the number of PV panels and curtailing their output power. When the intensity of daylight decreases, power is imported from the main grid through an AC/DC/AC converter or solid-state transformers in parallel to compensate for the shortage. By using a three-phase transformer in Δ-Y connection with Y’s neutral connected to its local grounding syste [...]

1284 8941

Open Access Short Review

Brief Review: Pancreatic Islet Transplantation for Type 1 Diabetes in Humans

Received: 13 February 2023;  Published: 17 May 2023;  doi: 10.21926/obm.transplant.2302184

Abstract

Pancreatic islet transplantation (ITx) has moved from the experimental phase of development to a position of an accepted and appropriate procedure to apply in clinical medicine. The primary indication for use of ITx is for management of dangerous and recurrent hypoglycemia secondary to use of exogenous insulin for management of hyperglycemia in people with type 1 diabetes. ITx involves procurement of a pancreas donated by a person who has died. The organ is taken to a specialized laboratory for isolation of islets [...]

1284 13042

Open Access Original Research

Bringing the Inside Out and the Outside in: The Therapeutic Relationship in Compassion Focused Therapy Chairwork

Received: 01 July 2023;  Published: 19 September 2023;  doi: 10.21926/obm.icm.2303037

Abstract

Chairwork is a central component in Compassion Focused Therapy (CFT). Despite its importance, there has been no prior research on the relational factors underpinning the application of chairwork in CFT. There is also a general paucity of research on the role of the therapeutic relationship in chairwork across modalities. This paper analyses data from interviews with 21 clients following a CFT chairwork intervention to ascertain how relational factors influenced their experience of this method. An Interpretative Phe [...]

1283 11202

Open Access Original Research

Retracted: Performance of Grouted Coupler Embedded in Reinforced Concrete ABC Bridge Pier at Vehicle Impact

Received: 27 September 2022;  Published: 03 January 2023;  doi: 10.21926/rpm.2301001

Abstract

Increased occurrence of dynamic loading on bridge piers caused by seismic, blast and vehicular impact incidences have been increasingly reported. Statistical data shows that while seismic and blast have received significant attention in the literature despite the frequency of occurrence of vehicular impact is remarkably higher. Unfortunately, pier damage caused by high velocity vehicle impact contemplates a little consideration. With the newer construction methods like accelerated bridge construction (ABC) and its [...]

1283 8391

Open Access Review

Review of Current Evidence in Acute Pancreatitis

Received: 17 May 2019;  Published: 12 July 2019;  doi: 10.21926/obm.hg.1903026

Abstract

Acute pancreatitis (AP) is an inflammatory condition of the pancreas and is one of the most common ailments of the gastrointestinal system that results in significant morbidity and mortality. The main etiologic causes of AP are alcohol consumption, gallstones, hypertriglyceridemia, and biliary stones. The clinical signs and symptoms, and diagnostic criteria of AP are well established in the literature and multiple studies. Multiple scoring systems have been used to predict the severity, prognosis, and mortality a [...]

1282 6860

Open Access Review

Comparison of Compressed Air Flow Measurement Techniques for Industrial Energy Efficiency Enhancement

Received: 31 October 2024;  Published: 24 June 2025;  doi: 10.21926/aeer.2502024

Abstract

Across the industrial sector, compressed air is utilized as an easy-to-use and readily accessible tool in a variety of applications. This tool is commonly misunderstood as being more efficient than it is in reality. Air compression is energy intensive and thus both economically and environmentally costly. Compressed air typically only achieves around ~15% efficiency if judged by the energy delivered from the air, meaning approximately 5-6 kWh are wasted for every 1 kWh of useful work performed by compressed air. Du [...]

1281 8051

Open Access Original Research

Taste Impairment and Compliance Improvement of Branched-Chain Amino Acids in Patients with Liver Cirrhosis

Received: 25 September 2018;  Published: 26 December 2018;  doi: 10.21926/obm.hg.1804011

Abstract

Background: Branched-chain amino acids (BCAA) are nutrients with a bitter taste, which causes low compliance in patients who need BCAA supplementation. Moreover, chronic liver disease is frequently complicated by taste impairment. The present study was designed to improve patient noncompliance regarding nutrients in liver disease. Methods: A taste questionnaire was administered to healthy controls, chronic hepatitis patients, and cirrhotic patients. Eleven different flavored powders that can be added to BCAA nutri [...]

1281 5684

TOP