Cytomegalovirus Management in Solid Organ Transplant Recipients
Abstract
1336 14895
Cytomegalovirus Management in Solid Organ Transplant RecipientsAbstract
Cytomegalovirus (CMV) remains a significant cause of morbidity and mortality in solid organ transplant (SOT) recipients. Despite advancements in prophylaxis and antiviral therapy, CMV continues to pose clinical challenges in transplant medicine. This review provides a comprehensive overview of CMV, exploring its pathophysiology, epidemiology, and clinical presentation in SOT patients, in whom CMV infection can lead to direct organ involvement and systemic symptoms. Additionally, CMV has indirect effects, including [...] 1336 14895 |
An Overview of the Hydrocarbon Sector in India for Carbon Capture ScopeAbstract
The hydrocarbon sector in India plays a pivotal role in the country's energy landscape, encompassing exploration, production, refining, and distribution activities. This abstract provides a concise overview of the sector's current status, challenges, and prospects. India's hydrocarbon reserves range from conventional to unconventional sources, with significant potential yet to be tapped. However, the sector faces challenges such as declining production from mature fields, technological limitations in ex [...] 1335 9673 |
Molecular Plant Physiology for Model Plants under Abiotic Stress ConditionsAbstract
Extreme temperatures, drought, and high soil salinity are some of the significant abiotic stresses that can severely impact crop yields, posing a threat to global food production. Comprehensive studies on model plant species are crucial for understanding their biochemical, physiological, and molecular responses to abiotic stresses. Identifying stress response mechanisms and potential targets can aid in developing stress-tolerant crop varieties. Additionally, elucidating the functions of reactive oxygen species is e [...] 1333 9139 |
The Safety of Oral Telomerase Activator in UV-Induced Skin Cancer with A Review of Telomerase in Aging and Skin CarcinogenesisAbstract
The supplement telomerase activator TA-65 (purified from Astragalus membranaceus) has been shown to retard cellular senescence, boost the aging immune system, and retard age-related symptoms. Lengthened telomeres retard aging, but because cancers often maintain longevity by lengthening telomeres, dietary telomerase activator might possibly increase tumorigenesis. This study investigated whether oral TA-65 effects the timing of onset and/or the incidence of skin cancers induced by UVB-irradiation and whether that po [...] 1333 20733 |
Unmasked Connections: Piloting Virtual Interactive Artist Performances in Healthcare — A Feasibility StudyAbstract
The arts offer many health benefits and can be especially impactful in hospital or continuing care facilities through group art interventions or personalized art activities. Arts can also be socially prescribed to fulfill social needs, improve emotional well-being, and have a positive impact of the social determinants of heath. This feasibility study explores the value of a pilot program that brought personalized virtual 1-on-1 art performances to residents in long-term care (LTC) during the Covid-19 pandemic which [...] 1332 493321 |
Innovative Strategies and Challenges for the Prevention of Pathological Anxiety in Children and AdolescentsAbstract
The effects of pathological anxiety on public health have led to the realization that anxious children might experience significant limitations in their lives. Evidence-based cognitive-behavioral (CB) interventions are now being implemented in schools at a group level to combat anxiety.Childhood emotional health should be considered a national and global priority for an effective strategy promoting the prevention of mental health. The aim of this study is the description of novel data on the effectiveness of preven [...] 1332 12277 |
Maternal Coping Mechanism and Its Associated Factors Following Perinatal Loss in Hospitals of Wolaita Zone, South Ethiopia 2021by
Abstract
Perinatal loss is the most painful and unanticipated experience for those who conceived and it is a major global concern worldwide, especially in developed countries like Ethiopia. Women who lost their pregnancy are believed to be at higher risk of developing severe grief following a loss. To reduce the risk of complications after perinatal loss, healthcare providers need to appreciate the grieving process and identify grief factors in mothers for early copying and to be managed promptly by providing adequate emoti [...] 1332 8502 |
Peptides Obtained by Enzymatic Decomposition of Mackerel Prevent Nonalcoholic Steatohepatitis in Sprague-Dawley Rats fed a High-fat and High-cholesterol Dietby
Abstract
Background: The pathogenesis of nonalcoholic steatohepatitis (NASH) is thought to be multifactorial, and oxidative stress may play an important role in the development of NASH. Peptides obtained by enzymatic decomposition of mackerel (EMP) including selenoneine were recently reported to possess antioxidative activity. Thus, EMP can be a candidate dietary strategy for the prevention of NASH. [...] 1331 6662 |
Organotin Polymers for the Control of Pancreatic Cancerby
Abstract
Pancreatic cancer is the fourth leading cause of death in the USA. Treatment is seldom successful. A wide variety of organotin polymers exhibit good inhibition of human pancreatic cancer cell lines AsPC-1 and PANC-1. The AsPC-1 is an adenocarcinoma pancreatic cell line and PANC-1 which is an epithelioid carcinoma pancreatic cell line. Synthesis is rapid employing commercially available reactants and the interfacial polymerization that is employed in the commercial synthesis of aramids and polycarbonates. 1330 7617 |
Using Music to Manage Anxiety: A Mixed Methods Intervention Study Between Two LockdownsAbstract
Lockdowns were a central strategy for managing the outbreak of COVID-19, and Melbourne, Australia had some of the most extensive restrictions globally during 2021. As a result, university students were faced with isolated living and challenging learning experiences. This pilot study occurred during 2021, close to both university assignment due dates and end of semester examinations and some of the longest lockdowns. Seventy-one participants responded to recruitment materials describing using music playlists to mana [...] 1330 10436 |
Molecular Genetic Study on VNTR-polymorphism of Two Cytokine Genes Antagonist of the Receptor of Interleukin 1 (rs2234663) and Interleukin 4 (rs8179190) Associated with Dental Caries in ChildrenAbstract
In this study, we investigated VNTR polymorphisms in intron 2 of the IL1RN gene (rs2234663) and intron 3 of the IL4 gene (rs8179190) related to the development of caries in school children (N = 196) with mixed bite dentition from Krasnodarskii Krai. The genotypes A1/A1 and L/L (L-"long" alleles) (rs2234663) provided resistance to the most intensive form of dental caries. The groups of children with DFC (decompensated form of caries) were significantly different from the pooled group SFC (subcompensated form of cari [...] 1328 9226 |
Alcohol Withdrawal Induced Malignant Catatonia and Response to Bromocriptine: Case ReportAbstract
Catatonia and malignant catatonia may result in devastating and life-threatening complications like pulmonary embolisms, pneumonia, deep venous thrombosis, rhabdomyolysis, and even death. There have been documented cases implicating alcohol withdrawal as a significant culprit in catatonia. Here, we provide a unique case report of a patient with a complicated medical course, who subsequently developed malignant catatonia secondary to severe alcohol withdrawal, and was successfully treated using both first line treat [...] 1328 10300 |
Subjective Assessments of the Pandemic Situation and Academic Adaptation of University Studentsby
Abstract
Students' academic adaptation during the pandemic is the key problem for the educational system. Even though certain success has been achieved in the organization of education with distance learning technologies and additional learning tools, there are still plenty of other difficulties that affect students' adaptation. The purpose of the study is to conduct a comparative analysis of academic adaptation's structure during and before the pandemic and to study the role of subjective assessments of the pandemic situat [...] 1328 8260 |
Study of the Development of Carotid Artery Atherosclerosis upon Oxidative Stress using Infrared Spectroscopy and Scanning Electron MicroscopyAbstract
In the present study, Fourier-transform infrared (FTIR) spectroscopy and Scanning Electron Microscopy (SEM) were used to investigate the formation and development of carotid artery atherosclerosis. The FTIR spectra showed that with the progression of atheromatic plaque formation, the collagen changed its native structure from ɑ-helix to random coil, amyloid, and cross-links. The infrared spectra and SEM analysis of carotid arteries showed that higher than 65% of the atheromatic plaque in patients with stenosis cons [...] 1327 10150 |
Building Blocks for an Energy TransitionAbstract
The present need for an energy transition in the wake of a global climate catastrophe led to the “EU green deal” which requires a transition of the energy system in all countries. This study aimis survey aims to identify strategies within such an energy transition based on global trend analyses and reports on available technologies for implementation. Based on a literature analysis of over 300 pieces (of feasibility studies and technology implementation reports with a focus on Central Europe) and a statistical anal [...] 1326 10025 |
Application of Epistemic Uncertainty Analysis and Sensitivity Analysis in Green Construction DesignAbstract
Building performance is often expressed according to primary energy use; however studies should also include environmental load. To mitigate the effects of increased CO2 emissions, green building designs are now increasingly popular options for stakeholders. In contrast, impacts of green design parameters, building performance assessment, and design optimization objectives are not addressed sufficiently for American infrastructure. Designing low-energy architecture to minimize carbon emissions requires thoughtful a [...] 1325 10162 |
Physical Illness and Emotional Expression in Late LifeAbstract
Louise H., Ph.D was referred to me by her long-term primary care physician (PCP) who was certain that his patient was seriously depressed and in need of medication and possibly psychotherapy. My own assessment, in consultation with a neurologist, was that Louise’s problems with coping were primarily neurological, and that her issues were due to serious (and in one case embarrassing) symptoms. Her neurological problems (mild Parkinsonism and PseudoBulbar Affect, or PBA) are currently being addressed by the neurologi [...] 1325 8302 |
Exploring Older Adults' Perceptions of Stair Hazards and an m-health Fall Prevention App: A Focus Group StudyAbstract
Older adults are disproportionately susceptible to hospitalizations and fatalities due to stair-related falls. While many intrinsic risk factors, such as mobility and vision, may increase the likelihood of falls on stairs, features of the stairs that increase the risk of falls are understudied. This study aimed to capture older adults’ perspectives of stair falls, as well as introduce the Safer Steps app and explore its feasibility in this population. This m-health technology was designed to gather data on st [...] 1325 14043 |
Wind Farm Layout Optimization Subject to Cable Cost, Hub Height, and a Feasible 3D Gaussian Wake Model ImplementationAbstract
We address the Wind Farm Layout Optimization (WFLO) problem and tackle the optimal placement of several turbines within a specific (wind farm) area by incorporating additional aspects of an economically driven target function. With this, we contribute three refinements for WFLO research: First, while many research contributions optimize the turbines' locations subject to maximum energy production or energy efficiency, we instead pursue a strategy of maximizing a profit objective. This enables us to incorporate inne [...] 1325 7665 |
Prevalence of Post-Traumatic Stress Disorder in General Population During COVID-19 Pandemic: An Umbrella Review and Meta-AnalysisAbstract
During the COVID-19 pandemic, global populations have experienced quarantine and lockdown restrictions, adversely affecting individuals' psychological well-being. This comprehensive review aims to estimate the prevalence of Post-traumatic Stress Disorder (PTSD) within the general population amidst the COVID-19 pandemic. Employing the PRISMA guideline, the databases PubMed/Medline, Science Direct, Web of Science, Cochrane and Google Scholar were used in the data extraction process, and publications from December [...] 1325 11442 |
Pandemics 2020 –COVID 19 Silent Hypoxia and Polysubstance Use: A Unique Case Reportby
Abstract
The coronavirus (COVID-19) pandemic continues to bring challenges in identification and management of which the “happy hypoxic” or silent hypoxia presentation has been found to present its own unique challenge. A 67-year-old African American COVID-19 positive female presents to the emergency department (ED) with a chief complaint of decreased oral intake and responsiveness, oriented and stable, with oxygen saturations found to drop as low as 47%. The patient was successfully managed with supplemental oxygen and det [...] 1324 7726 |
Traffic NOx Pollution Prediction and Health Cost Estimation Using Machine Learning: A Case Study of Toronto, Canadaby
Abstract
Road traffic is a significant source of air pollution that has a harmful impact on human health. To reduce the health and environmental impacts of fossil fuel consumption in the transportation sector, many countries have implemented policies to promote the deployment of electric vehicles (EVs). A vital factor to consider when designing policies to support EV use is the monetized health impacts of fossil fuel consumption. This research aims to investigate the health benefit of replacing internal combustion engine ve [...] 1324 9248 |
Some Aspects of Marine Meteorology and Air-Sea-Wetland-River Interactions During Hurricane Ida (2021)by
Abstract
In August 2021 Hurricane Ida devastated southeast Louisiana. On the basis of numerous pertinent meteorological-oceanographic (met-ocean) information including datasets and graphics as supplied by various public agencies, several unique topics related to marine meteorology and air-sea-land interactions are investigated. It is found that a newly proposed revised relation between minimum sea-level pressure and maximum sustained wind speed is verified during Ida. Characteristics of the rapid intensification, defined as [...] 1321 7450 |
Comparison of Household Environmental Factors among Children with Reported Asthma and Controlsby
Abstract
The present research was part of a cross-sectional project involving children aged 8 to 10 years in Porto, Portugal. The project involved a first research part at primary schools where the health tests and a questionnaire were performed and a second research part concerning environmental conditions. Two groups emerged from the health questionnaire answers: one group that reported “asthma diagnosed by a doctor” and/or “wheezing or whistling in the chest during last 12 months” and another that answered negatively to [...] 1321 7396 |
The Daclatasvir/Asunaprevir/Beclabuvir Combination Therapy for Chronic Hepatitis C Patients Experiencing Failure of IFN-Free DAA-Based Therapiesby
Abstract
Background: Daclatasvir/asunaprevir/beclabuvir (DCV/ASV/BCV) combination therapy had been available for the treatment of chronic hepatitis C patients with genotype 1 (CHG1) in Japan. Our aim was to report the efficacy and safety of DCV/ASV/BCV in patients experiencing treatment failure with interferon (IFN)-free direct-acting antiviral agent (DAA)-based therapies, which have not been fully evaluated.
Methods: We evaluated the efficacy and safety of 12-week DCV/ASV/BCV combination therapy for CHG1 patients experien [...] 1320 7990 |
Relationship between Brain Injury and Clinical Biomarkers in Hypoxic-Ischemic Newborn Pigletsby
Abstract
Background: The newborn affected by severe hypoxic-ischemic brain injury usually end up dying, and those who survive suffer neurodevelopmental handicaps. Biomarkers are required to identify the hypoxic-ischemic insult in order to determine the early rescue treatment method to be followed. The aim of the present study was to correlate relevant biomarkers to the pathophysiological process of hypoxic-ischemic brain injury at 6 h and 72 h in newborn piglets.
Methods:Hypoxia-ischemia was induced in the piglets by clampi [...] 1320 10042 |
Modeling Water Quality of AMD along the Flow PathAbstract
The water balance is severely disturbed in post-mining landscapes like Lusatia/Germany. Mine waters (amd) enter the environment and spread in groundwater and surface waters. Groundwater containing high amounts of pyrite weathering products flows into receiving waters due to lignite mining for several years. The Chair of Wassertechnik & Siedlungswasserbau at the Brandenburg University of Technology Cottbus-Senftenberg/Germany has developed a subsurface rehabilitation method using microbial sulfate reduction over the [...] 1319 6961 |
Unraveling the Impact of Modern Technologies on Young Minds: A Comprehensive StudyAbstract
The implementation of modern technologies has transformed connectivity, information-sharing, and education, significantly influencing students' academic journeys. New technologies offer advantages and disadvantages, particularly impacting young students and leading to changes in habits and behaviors. While technology can improve learning efficiency through personalized approaches, excessive screen time can negatively affect communication and academic performance. Studies recommend limited screen time for children t [...] 1318 10665 |
Cultural Biases and Psychedelic Experiences: Western Scientific Perspectives about Amazonian Mestizo Therapeutic TraditionsAbstract
This article aims to analyze how Western researchers can be influenced by their epistemic and ethical foundations, which are also expressed through a culturally shared idea of therapy, and how this influence can significantly hinder the understanding of a different cultural reality and its resources in terms of knowledge and practices. While examining a collection of research cases in the field of psychedelic therapy, the present paper focuses on the obstacles created by ethical and epistemic conflicts in the mind [...] 1317 13144 |
Tau-Targeted Immunotherapy for Alzheimer's Disease: Insight into Clinical TrialsAbstract
The use of immunotherapy as a therapeutic approach to Alzheimer's Disease (AD) is gaining rapid interest, with the primary goal of targeting abnormalities that impact neuronal viability through specific antibodies. Currently, clinical strategies focus intensively on targeting the two main pathologies associated with AD, beta-amyloid (Ab) and tau. This review examines ongoing research in the realm of tau immunotherapy, including clinical trials that demonstrate promising potential for halting AD progression. Several [...] 1316 15529 |
Stuart Stress Adaptation and Nola Pender's Model on Mental Nursing Care of Patients Schizophrenia: Case StudyAbstract
To describe the application of the Stuart Stress Adaptation and Nola Pender Models in mental nursing care for a patient with schizophrenia and risk of violent behavior. This research method used case studies. The sample is one patient with schizophrenia. Data collection is done through direct observation, interviews, and patient medical records. The results showed that the client showed a major nursing problem in the form of risk of violent behavior. Predisposing factors included passive childhood experiences and s [...] 1315 12856 |
Liver Transplantation or Resection for Treatment of Hepatocellular Carcinoma in Patients with Well-Compensated Cirrhosis: A Decision Analysis Modelby
Abstract
Background: Hepatocellular carcinoma (HCC) is a lethal tumor, for which liver resection and transplantation are the only potentially curative treatments. No prospective, randomized study has compared survival in patients with compensated cirrhosis after the two operations
Methods: Decision analysis modeling is an objective method to quantify risks and benefits. This study aimed to use decision analysis with a Markov model to estimate the impact of liver transplant and surgical resection on survival for patients wit [...] 1315 9889 |
Greater Objective and Perceived Competence for Clinics is Associated with Reduced Stress but No Change in Impostorism in Medical Students aAbstract
Impostorism is prevalent in medical students and negatively impacts wellness, contributing to stress and burnout. Perceived competence is noted as one attribute underlying impostorism. A curricular change that resulted in improved United States Medical Licensing Examination (USMLE) Step 1 scores and student self-perceptions of preparedness for clinical training was used as a natural experiment to assess the effects higher competence/preparedness, based on an objective indicator and self-perceptions, on impostorism, [...] 1314 8179 |
Array Formation Testing with Multiple Azimuthal and Axial Pressure TransducersAbstract
An early formation tester operating a “sink probe” that extracts fluids from the borehole, also measures pressures at its location; pressures are additionally collected at two passive sensors, one situated 180 deg away and the second about meter axially. These positions are not conducive to accurate permeability predictions, since pressure transient signals used for inverse analysis attenuate very rapidly. Closer probe spacings offer formation evaluation advantages at low mobilities because Darcy pressure dissipati [...] 1314 7012 |
Advancing Objective Pain Measurement: Exploring the Potential of Electroencephalography BiomarkersAbstract
Chronic pain involves complex cortical and subcortical changes, suggesting that brain electrical activity may be a potential biomarker for nociceptive processing. Pain leaves its signature in the brain's oscillatory patterns, yet limited studies have explored the neurophysiological alterations associated with chronic pain. This review examines the pain detection method currently used in clinical settings, the potential of neurophysiological features to become brain oscillatory brain biomarkers, and their use in fut [...] 1314 7836 |
Exploring the Potential of Phase Change Material for Thermal Energy Storage in Building EnvelopesAbstract
Buildings, with their significant energy consumption, pose a pressing concern for the future. Inadequate heating, ventilation, and air-conditioning (HVAC) systems further exacerbate thermal management difficulties and energy requirements. To address these challenges, Phase Change Materials (PCMs) offer valuable potential for sustainable energy reduction within the building sector, leveraging passive cooling and heating techniques. Numerical study has been conducted to explore the impact of embedding PCM within the [...] 1313 11227 |
Photodegradation of Polyethersulfone (PES), Polyvinylidene Fluoride (PVDF) and Polymethyl Methacrylate (PMMA) Microplastics via a Metal Organic Framework Namely ZIF-8/ZnO/CAbstract
The aim of this study was to photodegrade the Polyethersulfone (PES), Polyvinylidene fluoride (PVDF) and Polymethyl methacrylate (PMMA) microplastics using Zeolitic imidazolate framework-8/Zinc oxide/Carbon (ZIF-8/ZnO/C) nanocomposite generated under laboratory conditions. The produced nanocomposite was analysed using X-Ray Diffraction (XRD), Fourier Transform Infrared Spectroscopy (FTIR), X-Ray Photo Spectroscopy (XPS), Scanning Electron Microscope (SEM), Diffuse reflectance UV-vis spectra (DRS) and Electron Spin R [...] 1312 7087 |
Substance Use Disorder, Alexithymia, and Personality Disorders, What is the Link? Pilot African Studyby
Abstract
Alexithymia and personality disorders are common in substance use (SUD) patients. This association remains understudied and is considered to hurt the course and management of substance use disorder patients. To determine the prevalence of personality disorders (PD) and alexithymia in addiction care patients. Besides, we targeted investigating a possible link between alexithymia, different personality disorders and clinical aspects of substance use disorder including severity. This cross-sectional study was conducte [...] 1311 8999 |
Interstitial 1p36 Deletion Syndrome Encompassing CAMTA1 Gene: A Case ReportAbstract
Deletion of chromosome 1p36 encompassed various genes; however, the role of the CAMTA1 gene in the 1p36 region is less investigated. We report a child with developmental delay, a history of congenital heart abnormality, self-injurious behavior, nystagmus, and facial dysmorphism. Chromosomal microarray revealed a 257.2 kb deletion of chromosome 1p36.31, with CAMTA1 as the only involved gene. We explore overlapping clinical features of both chromosome 1p36 deletion and CAMTA1 intragenic deletion, including intellectu [...] 1310 6999 |
Associations between Health-Related Behaviours, Well-Being, and Academic Performance of Secondary School Students with Special Educational Need: A Secondary Analysisby
Abstract
Health-related behaviours (HRBs) have been considered one of the most critical public health issues, especially for those with special educational needs (SEN). Previous research suggests that health-related behaviours are highly likely to impact well-being and academic achievement. Diet is a crucial health-related behaviour that needs to be investigated along with factors such as sleep and exercise. The present study used data from the Cornish Academies Project, and secondary analyses were conducted to investigate [...] 1310 9168 |
Functional Prognosis of Spinal Cord Injury Due to Spinal TuberculosisAbstract
Spinal tuberculosis (TB), an extrapulmonary manifestation of TB, primarily involves one or multiple vertebrae, with a high prevalence at the thoracolumbar region, which can compromise spinal cord integrity and result in severe sequelae such as paraplegia, bladder and bowel dysfunction, and mobility limitation. This study aimed to review medical, surgical, and rehabilitation management, clinical outcomes, and prognostic factors of spinal TB with spinal cord injury (SCI). Research was conducted utilizing databases su [...] 1309 8828 |
Influence of Wetting-Drying Cycles on Wood Behaviour of Coastal Pedestrian Walkwaysby
Abstract
In the context of inspection and maintenance actions for beach walkways in the North of Portugal, some samples of wood used in their construction were collected – the Pinus sylvestris wood, widely applied in the country. The sustainability of the beach walkways over natural coastal areas is very dependent on their material durability. One of the main problems of the timber used to build those structures is its behavior under wet-drying cycles. For that reason, this work aimed to simulate the effects of weathering o [...] 1309 9387 |
An Estimate of Possible Impacts of Superoxide Chemistry on Seawater pH: A Mapping ExerciseAbstract
Superoxide, produced photochemically as well as microbially, is an important reactant present in seawater and a major source of hydrogen peroxide. Superoxide decay may occur through catalyzed or uncatalyzed dismutation forming H2O2 and O2, through oxidation to O2, or through reduction into H2O2. Under definite circumstances, the redox processes that are different from dismutation could produce or consume H+, thereby altering the pH of seawater. In order to alter the pH, these processes have to involve, together wit [...] 1308 8068 |
Cyanobacterial Biofuel: A Platform for Green EnergyAbstract
Cyanobacteria have great potential as a platform for biofuel production because of their fast growth, ability to fix CO2 gas, and genetic tractability. They also preserve the sustainability of an ecosystem without harming the environment. High-performance biofuels made from cyanobacteria can be utilized as a base for the production of green energy. Although a lot of studies have been conducted where plants and crops are used as the source of energy, cyanobacteria have been reported to have a more efficient photosyn [...] 1308 9758 |
Alpha-1 Antitrypsin Deficiency and Lung Transplantation: A Clinical Caseby
Abstract
Background: Alpha-1-antitrypsin (AAT) deficiency is the most common hereditary disorder in adults and is associated with an increased risk of developing lung emphysema.
Methods:Here, we report the case of a 54-year-old man, who underwent bilateral lung transplantation due to AAT deficiency emphysema in the general hospital of Siena, Italy.
Results:The patient was diagnosed with partial AAT deficiency (189 mg/dL) associated with the PIMZ genotype; although he quit smoking, his lung disease progressed to chronic resp [...] 1307 9803 |
Where Older Patients with Cancer Die? A Retrospective Studyby
Abstract
Home is the preferred place of death for most cancer patients. We examined which characteristics of older patients with cancer may have influenced this choice and how important may be relevant an early collaboration between oncologists and palliatives. Hospitalized patients aged ≥70 were screened by G8 questionnaire and evaluated by Comprehensive Geriatric Assessment (CGA) to identify frail and unfit ones and define the most appropriate end-of-life setting with palliatives. Using the G8 questionnaire, we screened 1 [...] 1306 5504 |
Advances in Wind Farm Layout Optimization: Wind Direction Robustness and Wake Induced Asymmetric Thrust LoadAbstract
In this study, we address the wind farm layout optimization (WFLO) problem and tackle the issue of optimal turbine placement by incorporating additional aspects of an economically driven target function. Firstly, we have analyzed the effect of wind direction on a given turbine arrangement. Based on the direction-dependent wake pattern, practitioners sometimes shut down certain turbines on their farms. Our method computes which turbines should be shut down in which wake situation. On this basis, we have developed a [...] 1306 9108 |
Diabetes and Sarcopenia: Intersection of Co Morbid ConditionsAbstract
Sarcopenia is more common in persons with type 2 diabetes mellitus (T2DM) than in persons without diabetes. There is overlap of some pathophysiologic features of sarcopenia and T2DM. In addition, the risk for sarcopenia is associated with common complications of T2DM including renal disease, cardiovascular disease and neuropathy. Glycemic control in T2DM may have some benefits on sarcopenia. The specific effects of glucose lowering agents on sarcopenia suggest that metformin, insulin, thiazolidinediones and GLP1 re [...] 1304 7209 |
TOP