by Katharina Reichelt  , Ewan James  , Daniel Thompson  and Shaun Tanney

Received: 14 August 2022;  Published: 18 January 2023;  doi: 10.21926/obm.geriatr.2301222

This article discusses the findings from a training programme called ‘Communication and Interaction Training’ (CAIT). CAIT was designed to improve the confidence of carers in their use of communication skills with people living with dementia, particularly when managing behavioural agitation. This pre/post assessment study employed a mixed design, and showed positive effects in terms of quantitative and qualitative features. The participants were mainly from a specialist team who were experienced in managing episode [...]

by Tammy Lennox  and Angela Kennedy

Received: 08 February 2022;  Published: 20 July 2023;  doi: 10.21926/obm.icm.2303030

The current article describes the application of the Compassion Focussed (CF) formulation to the interaction between individuals and their social context. The standard CF formulation [1] would see the person’s fears as inadvertently reinforced by their attempts to cope with the underlying issue. However, sometimes such attempts to cope can also reinforce the fears of another person or party. Interpersonal CF formulations could provide a compassionate, non-blaming way of enlightening people in their interactions to [...]

by Negar Gorjizadeh  , Payam Saadat  , Abbas Azadmehr  and Saeed Irian

Received: 09 June 2025;  Published: 11 September 2025;  doi: 10.21926/obm.genet.2503310

Genetic factors including TNF-β and DRD2 have been considered as essential components in the etiology of migraine. Several studies have investigated the association between TNF-β +A252G or DRD2 C939T polymorphisms and migraine risk, with debatable results. We aimed to examine whether TNF-β +A252G and DRD2 C939T polymorphisms confer genetic susceptibility to migraine in a Northern Iranian case-control sample. In total, 151 migraineurs (105 with MO 46 with MA) and 144 healthy control subjects were included in this st [...]

by Kristin Drexler  and Ed Boles

Received: 02 March 2024;  Published: 25 July 2024;  doi: 10.21926/aeer.2403017

Watershed health and integrity are essential to human and ecosystem health and well-being. New River watershed communities in northern Belize, Central America are vulnerable to annual ‘cultural eutrophication’ - natural eutrophication exacerbated by human activity. Human-caused pollution from agriculture, septic effluent, and industrial drainage, in combination with extended drought and the slow flow of New River, has caused more frequent and prolonged periods of eutrophication. In this qualitative study, 42 New Ri [...]

by Jennifer A. King  , Megan R. Holmes  , Kylie Evans  , Anna E. Bender  and Dakota King-White

Received: 28 February 2023;  Published: 07 September 2023;  doi: 10.21926/obm.icm.2303036

The COVID-19 pandemic exacerbated the long-standing issues of stress and burnout in the education sector, with teachers and education staff facing unprecedented challenges including significant adjustments to teaching methods and balancing the mental health and academic needs of their students. The resulting challenges have contributed to heightened levels of stress and burnout among teachers and education staff. The impact of the pandemic on teachers and education staff has highlighted the need for greater support [...]

by Elham Amjad  and Babak Sokouti

Received: 21 February 2025;  Published: 09 June 2025;  doi: 10.21926/obm.transplant.2502251

Graft rejection, early allograft dysfunction (EAD), and poor diagnostic accuracy are some of the challenges that still need to be addressed, even though liver transplantation (LT) has the potential to help patients with end-stage liver disease (ESLD) significantly. Traditional procedures, such as liver biopsies and liver function tests (LFTs), often fail to identify abnormalities early and with accuracy. Genomic RNA sequencing (RNA-Seq) has recently emerged as a powerful approach for identifying molecular markers o [...]

by Nasim Foroughi  , Laura Douglass  , Caroline A. Smith  and Phillipa Hay

Received: 11 July 2022;  Published: 09 October 2022;  doi: 10.21926/obm.icm.2204047

Depression and mental health-related issues are increasingly prevalent in young adolescents and adults and so is the use of Complementary Therapies (CTs) to treat depression. Systematic reviews have found that, of all CTs, acupuncture, exercise, and the herbal remedy St John’s Wort have the greatest amount of evidence for efficacy in treating depression. We aimed to assess Mental Health Literacy (MHL) levels in the treatment of depression and Complementary Therapy’s (CT) usage in adolescents and adults. Surveys wer [...]

by Roy G Beran

Received: 01 July 2022;  Published: 13 September 2022;  doi: 10.21926/obm.geriatr.2203204

This paper examines sleep disorders in older people, focusing on Parkinson’s disease (PD). It defines PD and explores those conditions associated with sleep disorders and their relationship to PD. It identifies specific conditions which cause sleep disoders in patients with PD, namely: REM sleep behaviour disorder (RDB) which may be a precursor to PD; obstructive sleep apnoea (OSA) which is very prevalent amongst people with PD; depression and mood disorders which both increase with age and are more common in peopl [...]

by James S. Powers  , Shana Atkins  and Allison B. McCoy

Received: 05 June 2022;  Published: 28 September 2022;  doi: 10.21926/obm.geriatr.2203205

Many health systems have joined the Age-Friendly Health Systems movement to provide every older adult safe, high-quality care aligned with what matters most. Becoming an Age-Friendly Health System means that hospitals and health care systems reliably use a set of evidence-based practices known as the “4M’s” – What Matters, Medication, Mentation, and Mobility – to provide care for older, disabled and medically complex patients across all care settings. Implementing the Institute for Healthcare Improvement’s (IHI) 4M [...]

by Giulio E. Lancioni  , Gloria Alberti  , Chiara Filippini  , Alessandra Fiore  , Clarissa Simonetti  , Nirbhay N. Singh  , Mark F. O'Reilly  and Jeff Sigafoos

Received: 09 October 2023;  Published: 02 January 2024;  doi: 10.21926/obm.neurobiol.2401203

This study adapted a new interactive technology system to help six participants with intellectual disability and visual and motor impairments to exercise relevant physical responses as part of an occupational task. The task was to place objects into different containers from a sitting position. The responses, which changed across sessions, consisted of the participants (a) stretching the left arm and shoulder to place objects in a container located to their left, (b) stretching the right arm and shoulder to place o [...]

by Nadia A. Abdelmegeed Abdelwahed

Received: 08 January 2024;  Published: 06 May 2024;  doi: 10.21926/obm.neurobiol.2402222

In the present era, a healthy life is a challenge for everyone. Therefore, diverting individuals' minds towards physical activity and exercise is necessary for the day. This paper proposes to inspect the impact of physical activity on the development of intention to exercise (ITE) among entrepreneurs. The quantitative study collected data from 383 Egyptian entrepreneurs through a survey questionnaire. Most respondents were males (n = 257 or 67.10%) against females (n = 126 or 32.90%). The range of age of the respon [...]

by Somayeh Alimoradi Askari  , Mehdi Nasr Esfahani  , Kowsar Shirazi  , Arman Nasr Esfahani  , Hossein Zeinalzadeh-Tabrizi  and Mojtaba Mohammadi

Received: 23 January 2024;  Published: 28 April 2024;  doi: 10.21926/obm.genet.2402231

Garlic (Allium sativum), cultivated worldwide for its medicinal and nutritional value, faces challenges due to diseases caused by various pathogens. In this study, eleven garlic genotypes from Iran and one from China were selected and sown under natural infection rendered by the rust fungus (Puccinia alli) over two consecutive years. Subsequently, disease distribution and severity, percentage of infection and susceptibility of different garlic genotypes to rust disease were investigated. The results showed that gen [...]

by Darcy A Hille  , Sverre E Kjeldsen  , Stevo Julius  , Kristian Wachtell  , Peter M Okin  and Richard B Devereux

Received: 30 December 2021;  Published: 24 February 2022;  doi: 10.21926/obm.geriatr.2201189

We aimed to assess some readily available patient characteristics such as urinary albumin excretion as predictors of a primary composite event of myocardial infarction, cerebral stroke, and cardiovascular death among patients with hypertension and left ventricular hypertrophy, and develop risk algorithms for the outcomes. A “Cox proportional hazards” model identified the baseline variables that significantly affected the occurrence of the composite endpoint in 9193 elderly hypertensive patients with lef [...]

by Vladimir N. Bashkin

Received: 05 September 2022;  Published: 13 October 2022;  doi: 10.21926/aeer.2204040

This research aims at one of the most important economic and environmental problems - the elimination of the consequences in case of emergency spills while cleaning petroleum products. The objectives of the study include the development and production of new biological products and biosorbents based on carbon-oxidizing microorganisms, testing the developed technologies for environmental risk management to eliminate the consequences of emergency petroleum product spills, creating an algorithm for conducting prelimin [...]

by Anna A. Pendina  , Mikhail I. Krapivin  , Irina D. Mekina  , Irina V. Aleksandrova  , Yanina M. Sagurova  , Evgeniia M. Komarova  , Mariia A. Ishchuk  , Andrei V. Tikhonov  , Olesya N. Bespalova  , Alexander M. Gzgzyan  , Igor Yu. Kogan  and Olga A. Efimova

Received: 13 May 2022;  Published: 23 September 2022;  doi: 10.21926/obm.genet.2203164

This paper suggests an approach for the use of a single paucicellular histological sample to investigate two characteristics indicative of the cell’s functional potential: 1) the content of telomerase reverse transcriptase (TERT) and 2) the telomere length. An algorithm has been suggested for the successive detection of the catalytic telomerase subunit with immunohistochemical staining and assessment of telomere length with Q-FISH on the same set of cells. The described approach uses three incontestable advantages [...]

by Lamiae Afif  , Zhour El Amrani  , Aziza Sbiti  , Ilham Ratbi  , Imane Cherkaoui Jaouad  , Youssef El Kadiri  , Thomas Liehr  , Abdelaziz Sefiani  and Abdelhafid Natiq

Received: 02 April 2024;  Published: 30 August 2024;  doi: 10.21926/obm.genet.2403259

6q22.31q27 duplication and Xq28 deletion lead to two specific different rare chromosomal disorders. Partial trisomy 6q22.31q27 is a recognizable syndrome with a distinctive phenotype, and the most common finding in girls with Xqter deletions has been premature ovarian failure (POF) and secondary amenorrhea. To our knowledge, neither abnormality in one patient has yet been reported. A 10-year-old girl with de novo 6q22.31q27 duplication and Xq28 deletion was diagnosed by chromosomal microarray and confirmed by fluor [...]

by Lie Zhang  , Reza D. Fakhrabadi  , Maryam Khoshkhoo  and Husien Salama

Received: 29 December 2021;  Published: 09 October 2022;  doi: 10.21926/jept.2204031

Integrating large-scale wind energy in modern power systems necessitates high-efficiency mathematical models to address classical assumptions in power systems. In particular, two main assumptions for wind energy integration in power systems have not been adequately studied. First, nonlinear AC power flow equations have been linearized in most of the literature. Such simplifications can lead to inaccurate power flow calculations and result in technical issues. Second, wind power uncertainties are inevitable and have [...]

by Giacinto Libertini

Received: 22 July 2022;  Published: 14 October 2022;  doi: 10.21926/obm.geriatr.2204208

The interpretation of aging as an adaptive and programmed phenomenon implies the existence of specific genetically determined and regulated aging-causing mechanisms. This interpretation is in contrast to the explanation of aging as the gradual accumulation of the effects of harmful factors that are only partially countered by natural selection. The subtelomere–telomere theory of aging offers what is required by the interpretation of aging as a programmed phenomenon. The experimentally documented mechanisms that are [...]

by Suzanne Fleming  , Mary Beth Arensberg  , Kirk Kerr  and Robert Blancato

Received: 22 November 2022;  Published: 10 March 2023;  doi: 10.21926/obm.geriatr.2301227

Older adults have a heightened risk of malnutrition that occurs with age. Many factors can increase their risk for malnutrition, including factors associated with disease, function, social and mental health, and hunger and food insecurity. Risk for malnutrition is also linked to disparities and may disproportionately impact people living in rural areas. This Perspective paper outlines the issue of malnutrition and its impact on health outcomes and health disparities as well as summarizes existing evidence on malnut [...]

by Manon Dethoor  , François Vialatte  , Marion Martinelli  , Pauline Peri  , Christophe Lançon  and Marion Trousselard

Received: 23 August 2022;  Published: 28 December 2022;  doi: 10.21926/obm.icm.2204058

While there is abundant literature on the benefits of Mindfulness-Based Interventions (MBI), data about factors associated with their Efficiency are scarce. Our study attempts to determine the moderators of efficacy and adherence in Mindfulness-Based Cognitive Therapy (MBCT) with a machine learning analysis. Seventy-six psychiatric outpatients at “university hospital mental health service” had a prescription for MBCT from their referring psychiatrist. They suffer from various psychiatric illnesses with [...]

by Syd Hiskey  and Neil E Clapton

Received: 07 April 2024;  Published: 21 May 2024;  doi: 10.21926/obm.icm.2402029

The work of psychotherapy demands much of those who engage in it. Compassion provisioned by therapists requires varying competencies, yet remains a highly embodied and enactive endeavour. Therapist skill can be cultivated in this area and enhanced through a variety of body-mind trainings, including various forms of therapist personal practice. However, much clinical training/continued professional development centres on education workshops, emphasising knowledge above skill. Given this we present feasibility data f [...]

by S.Amitha Banu  and Khan Sharun

Received: 25 May 2023;  Published: 02 June 2023;  doi: 10.21926/obm.transplant.2302187

Platelet-rich plasma (PRP) is a promising tool in regenerative medicine because it stimulates tissue repair and regeneration. PRP contains a high concentration of platelets, growth factors, and cytokines involved in the healing process. This editorial paper aims to give an overview of PRP in regenerative medicine and its potential applications in various medical fields such as orthopedics, dentistry, dermatology, and wound healing. PRP can be integrated with other regenerative therapies, such as stem cell and gene [...]

by Evanthia Asimakopoulou  and Periklis Zavridis

Received: 11 April 2023;  Published: 08 November 2023;  doi: 10.21926/obm.neurobiol.2304194

Chronic pain in post-critical care patients is a multifaceted issue with profound implications for patient well-being and quality of life. This review aims to address the rehabilitation of patients who suffer from chronic pain following discharge from the intensive care unit (ICU). Despite growing awareness of the prevalence and impact of this condition, significant gaps in knowledge persist regarding the optimal rehabilitation strategies for these patients. To conduct this study, an extensive literature search was [...]

by Rohman Hikmat  , Iyus Yosep  , Popy Siti Aisyah  and Shella Febrita Puteri Utomo

Received: 03 December 2024;  Published: 26 March 2025;  doi: 10.21926/obm.neurobiol.2501281

This study aims to describe the application of forgiveness therapy as a psychosocial intervention for a schizophrenia patient with violent behavior. Mr. M, a 19-year-old male diagnosed with schizophrenia, exhibited psychotic symptoms, including auditory hallucinations, persecutory delusions, agitation, and aggression. He had a history of trauma due to physical violence from his brother. The patient was diagnosed with a risk for violence toward others. Forgiveness therapy was implemented over six sessions, each last [...]

by A. Guillermo Bracamonte

Received: 28 July 2023;  Published: 15 November 2023;  doi: 10.21926/rpm.2304034

This mini-review discussed the best-known chemical and synthetic methodologies used in the last years to modify carbon allotropes, with an interest in nanotechnology. In this perspective, chemistry with optoelectronics applications and recent trends within bio-applications focusing mainly on graphene and its derivatives were considered. So, the mini-review intended to focus on methodologies to add functional groups with varied reactivities, polymer chemistry, and nanoscale control. These methodologies provide insig [...]

by Ana Pérez-González  and Ismael El Hajra

Received: 17 November 2024;  Published: 13 May 2025;  doi: 10.21926/rpn.2502010

In recent years, the incidence of Inflammatory Bowel Disease (IBD) has risen significantly in the Western population, pointing toward the potential influence of environmental and dietary factors. In order to explain this, some research on nutritional therapy identifies exclusive enteral nutrition (EEN) as a highly effective approach for managing IBD in children. This treatment achieves high remission rates; more specifically, some clinical trials have reported remission rates from 70% to 100%. EEN not only facilita [...]

by Vsévolod Mymrin  , Reinaldo H. G. Alarcon  , Marilia A. Guidolin  , Kirill Alekseev  , Rogerio J. Hultmann  , Walderson Klitzke  , Karina Q. Carvalho  , Fernando H. Passig  , Charles W.I. Haminiuk  and Rodrigo E. Catai

Received: 08 December 2022;  Published: 27 February 2023;  doi: 10.21926/cr.2301009

Methanol synthesis catalyst (MSC) waste was applied as the principal component (till 70 wt.%) of sustainable ceramics in composites with bauxite processing waste (RM), and waste foundry sand (FS). The results of the initial components' chemical interaction studies by a complex of methods (XRD, SEM/EDS/mapping, AAS and LAMMA) during heating demonstrated the synthesis of amorphous glasslike new formation, their filling of pores and compaction of the ceramic’s structure. In this case, a strong chemical and mechanical [...]

by Igor Val Danilov  and Sandra Mihailova

Received: 09 November 2022;  Published: 28 April 2023;  doi: 10.21926/obm.neurobiol.2302167

This expanded conference paper reports the results of a psychophysiological research study on shared intentionality conducted in 24 online experiments with 405 subjects (208 recipients and 197 contributor-confederates). In this research, we created a bioengineering system for assessing shared intentionality in human groups by modeling mother-neonate dyad properties in subjects during solving unintelligible multiple-choice puzzles. In this model, only the mother (contributor-confederate) knows the correct stimulus a [...]

by Sofie Amalie Andersson  , Mathias Møller Thygesen  , Anita Dittrich  and Henrik Lauridsen

Received: 07 March 2022;  Published: 06 July 2022;  doi: 10.21926/obm.neurobiol.2203127

The Mexican axolotl salamander is an important model species in regenerative medical research and experiments involving this species often require anesthesia which is usually limited to the duration of the surgical procedure or other interventions, usually lasting no more than a few hours. This study aimed to examine the potential for increasing the duration of anesthesia by continued propofol infusion for a week. Neurobehavioral changes in response to prolonged anesthesia were evaluated after two and seven days of [...]

by Sujeet Kumar Thakur  and Sambasivan Venkat Eswaran

Received: 17 June 2023;  Published: 01 September 2023;  doi: 10.21926/rpm.2303032

The Inert soil obtained from the Ghazipur Municipal Solid Waste landfill located in East Delhi, India has been used as the starting material for the work described in this paper. This mountain-like monster is often in the news for its bad smell, pollution of the groundwater in the area from its leachates, and the occasional fires in it endangering the lives of the people living nearby. Landfills produce many greenhouse gases (CO2, CH4, CO, HCHO, H2S, and NH3) which are poisonous and cause environmental pollution in [...]

by Sofia Oliveira Correia  , Catarina Eusébio  , Ana Sofia Cipriano  , Virginia Lopes  , José Ramón Vizcaíno  , António Cabrita  , Manuela Almeida  , Sofia Pedroso  , Leonidio Dias  , La Salete Martins  and António Castro Henriques

Received: 18 October 2018;  Published: 07 March 2019;  doi: 10.21926/obm.transplant.1901057

Mucormycosis is an angioinvasive and potentially fatal fungal infection caused by ubiquitous filamentous fungi. Cutaneous mucormycosis is an emerging infection and potentially lethal. Our aim was to review the literature on cutaneous mucormycosis. We present a case of a renal transplant patient with a surgical wound infection 20 days after kidney transplant. This case is an example on how early diagnosis is crucial and, since culture is less sensitive, microscopic evaluation of the characteristic broad hyphae is th [...]

by Michael Lincoln  , Stephen Aichele  , Emma L.M. Clark  , Maggie Dungan  , Ashley Harvey  , Lillian Hoyer  , Yuqin Jiao  , Steffany Josslin  , Frances Russell  and Zeynep Biringen

Received: 12 May 2023;  Published: 27 July 2023;  doi: 10.21926/obm.icm.2303032

Fathers are a historically underrepresented population in developmental research and must be considered for their modern presentation in parenting processes. Emotional Availability (EA) is a construct that captures the parent-child relationship quality and predicts positive outcomes for children. A recently developed intervention, the EA Brief, is a program conceptualized for easy administration that may be utilized to improve father-child dyadic functioning across a range of child ages. The final sample of interes [...]

by Stefan Klek  , Jonathan Newgren  , Philip Burns  , Angelika Kwak  , Eric Casinelli  , Tony Tu  , Theodote K. Pontikes  and Edwin Meresh

Received: 10 May 2023;  Published: 13 October 2023;  doi: 10.21926/obm.neurobiol.2304188

Neuroleptic Malignant Syndrome (NMS) and Malignant Catatonia (MC) are conditions with significant overlap and are classically characterized by autonomic dysfunction, rigidity, bradyreflexia, posturing, lead-pipe rigidity in the former and waxy flexibility in the latter, stereotyping, an increase in creatinine kinase, and/or leukocytosis. Onset after inciting factor ranges from days to weeks, as does resolution with appropriate treatment. The overlap in symptomatology with Autism spectrum disorder (ASD) presents a f [...]

by A. Maya Kaye

Received: 14 October 2023;  Published: 27 April 2024;  doi: 10.21926/obm.icm.2402024

Fueled by decreased state support, economic pressures, and a growing emphasis on academic capitalism, higher education in the United States faces significant challenges. These shifts have fostered fast-paced, competitive environments, impacting the quality and equity of faculty-student mentoring in graduate programs, particularly for Black, Indigenous, People of Color (BIPOC), and first-generation students. This article proposes a novel framework, the compassion-focused mentoring conceptual model (CFM-CM), to addre [...]

by Jeggathishwaran Panisilvam  , Peng Cheng Wang  and Hui An

Received: 26 March 2022;  Published: 13 July 2022;  doi: 10.21926/jept.2203024

Reducing and conserving fuel usage is pivotal for any engineering system for the development of a sustainable energy solution. Proton exchange membrane fuel cells (PEMFCs) are one of the promising renewable energy systems that consume hydrogen as their source of fuel to generate electricity. This paper investigate the necessity of the constant supply of fuel (hydrogen) in the PEMFC system to ensure stable operation. We propose that a dynamic supply of fuel could help achieve similar performance and reduce the amoun [...]

by Hidehiro Kamezaki  , Tatsuo Kanda  , Osamu Yokosuka  , Yasunori Kasahara  and Takayuki Sakurai

Received: 16 November 2016;  Published: 21 January 2017;  doi: 10.21926/obm.hg.1701001

(1) Background: Preventative treatment for Pneumocystis jirovecii pneumonia (PCP) has been recommended for patients receiving ≥20 mg/day prednisolone. We describe a patient who developed PCP while receiving a dose of 15 mg/day prednisolone, and consider criteria for the initiation of preventative therapy for PCP in patients with autoimmune hepatitis (AIH) treated with prednisolone. (2) Case Report: A 71-year-old woman initially possessed dark-colored urine, white stool, and decreased appetite, which indicated hepat [...]

by Joana Sousa

Received: 15 May 2023;  Published: 15 January 2024;  doi: 10.21926/aeer.2401003

The climate change and the social crisis launched the basis for the policy discussion about future trajectories of development and sustainability. Innovation policies are expected to promote the transformation of complex socio-technical systems and call for fundamentally different societal production and consumption patterns. This is strictly associated with energy systems and energy policies. A policy framework was conceptualized considering three levels approach: the policy shape at the micro level, the policy co [...]

by Giuseppe Cocco

Received: 20 March 2020;  Published: 01 April 2020;  doi: 10.21926/obm.geriatr.2002112

by Ana Valado  , Márcia Morais  , Stephanie Fortes  , Joana Rosado  , João Paulo Figueiredo  and Armando Caseiro

Received: 20 November 2023;  Published: 21 May 2024;  doi: 10.21926/obm.icm.2402028

Hydrotherapy is highly recommended for older adults because it offers warmth and support, so people with pain or reduced mobility and balance can move and exercise more freely compared to regular physical activity. The high plasma antioxidant capacity of uric acid in neutralizing oxidative species and the importance of nitric oxide (NO) in vasodilation and inflammatory response are relevant in older adults. This work aimed to evaluate hydrotherapy's effect on uric acid and NO concentrations in a population aged ≥ 6 [...]

by Amjad Mizyed

Received: 23 December 2024;  Published: 21 April 2025;  doi: 10.21926/jept.2502007

Water scarcity is one of the most pressing global challenges, particularly in arid and semi-arid regions. In this context, the Gaza Strip, where groundwater is the only available natural water resource, faces severe water stress due to overexploitation and drought conditions. This study aimed to review the recent water budget for the Gaza Strip by collecting data for the years (2021-2022) which was analyzed, discussed, and compared with other studies. The results showed a sharp deterioration in the Gaza Strip in te [...]

by Brandon M Menachem  , Sandrine Hanna  , Deepika Kulkarni  and Hakim Azfar Ali

Received: 08 June 2023;  Published: 21 November 2023;  doi: 10.21926/obm.transplant.2304202

Treatment options for end stage lung diseases are limited to stabilizing lung failure, decreasing disease progression, and symptom management, but significant reversal of lost lung function is often not possible. For well selected patients, lung transplantation may be a viable option to improve both longevity and quality of life. Though outcomes for lung transplant recipients have improved over several decades, long term survival still lags behind that of other solid organ transplant recipients. Longevity after lun [...]

by Vikas Dhikav  , Prerna Bhati  , Pankaj Kumar  and Praveen Kumar Anand

Received: 18 June 2023;  Published: 05 August 2024;  doi: 10.21926/obm.geriatr.2403284

This scoping review aims to review the effectiveness of yoga as a complementary intervention for improving mental health outcomes in the geriatric population globally. Yoga is practiced by millions worldwide. Since practitioners of yoga claim to have calmer minds and better psychological and physical health, this topic needs to be reviewed at length. There is a considerable treatment gap worldwide in treating mental disorders, especially in old age, and there is a shortage of low-cost, feasible, and acceptable prev [...]

by HIrotaka Yamamoto  , Maiko Kisino  , Shunichi Nakamura  and Kastutoshi Tokushige

Received: 12 November 2018;  Published: 27 December 2018;  doi: 10.21926/obm.hg.1804012

Objective: Elastography is a non-invasive examination method that can estimate the extent of liver fibrosis, measured as liver stiffness (LS). We examined the relationship between gastro-esophageal varices and the LS and how to predict esophageal varices and varices bleeding by LS. Methods: From 2014 to 2016, we conducted a retrospective study of 138 subjects, all of whom were patients with chronic liver disease, including NAFLD, alcoholic liver disease, primary biliary cholangitis, viral hepatitis, and others. LS [...]

by Morgan A. Valley  and Lorann Stallones

Received: 30 June 2021;  Published: 12 September 2021;  doi: 10.21926/obm.icm.2103029

Hospice care workers are exposed to the hazards associated with in-home care in uncontrollable environments as well as occupational stress related to caring for terminally ill patients and their families. This study aimed to assess the effectiveness of an abbreviated mindfulness intervention to improve hospice care worker occupational safety performance and well-being. This study used a single-group pre-post design to pilot test an 18-hour mindfulness training as an intervention on self-reported safety performance [...]

by Zakhar Slukovskii  and Tatiana Shelekhova

Received: 09 March 2023;  Published: 05 July 2023;  doi: 10.21926/aeer.2303038

Core sediment (sapropel) samples were collected from Lake Okunozero, the Republic of Karelia, Russia, to assess the distribution of heavy metals and their main fractions, probable sources of pollution, and potential ecological and toxicological risks for the water body. Heavy metal concentrations were measured by the mass spectrometry method using an XSeries-2 ICP-MS. The sequential extraction of heavy metals from sapropel samples was performed using the scheme of Tessier. According to the Russian Interstate Standa [...]

by Kenneth J. McLeod

Received: 24 April 2023;  Published: 18 September 2023;  doi: 10.21926/obm.geriatr.2303249

Chronically low blood pressure in older adults is associated with significantly increased long-term risks of dementia and all-cause mortality risk. Yet low blood pressure is generally not treated until an individual begins to experience the acute symptoms arising from very low cerebral perfusion. However, these acute symptoms, such as dizziness, balance difficulty, syncope, increased fall occurrence, vision impairment, and nausea, begin to occur only at very low blood pressure levels, such that mean arterial pressu [...]

by Jean-François Cadranel  and Jean-Baptiste Nousbaum

Received: 21 August 2019;  Published: 15 April 2020;  doi: 10.21926/obm.hg.2002045

The literature on the prevalence of spontaneous bacterial peritonitis (SBP) in cirrhotic outpatients who visited the hospital for therapeutic abdominal paracentesis was reviewed in order to assess the usefulness of urinary strips in this setting. The authors reviewed the studies published as peer-reviewed articles on the prevalence of SBP in ambulatory outpatients who visited the hospital for therapeutic paracentesis. Five such studies were available in the literature. It was found that the prevalence of SBP was in [...]

by Luis F. Riquelme  , Sara Diab  , Angela Horyacheva  , Isabel Huribal  , Andreea Shellerud  , Sophia Werden Abrams  and Ashwini M. Namasivayam-MacDonald

Received: 29 April 2022;  Published: 11 August 2022;  doi: 10.21926/obm.icm.2203036

The purpose of this study was to collate and summarize the content covered in published literature describing speech-language pathology management of adult patients with COVID-19 in the acute hospital setting as of February 2022. This review serves as an updated review of the initial recommendations to guide speech-language pathology management for adults with COVID-19 in the acute hospital setting previously provided by Namasivayam-MacDonald and Riquelme in July of 2020. This scoping review followed the Preferred [...]

by Che Aishah Nazariah Ismail  , Nazlahshaniza Shafin  , Khairunnuur Fairuz Azman  , Idris Long  and Nor Syafinaz Yaakob

Received: 28 September 2024;  Published: 09 April 2025;  doi: 10.21926/obm.neurobiol.2502283

Chronic pain is a significant and global healthcare issue that hugely implies the quality of life and productivity of the affected individuals. It is challenging to treat and thus necessitates a deeper understanding of its underlying pathomechanisms to develop targeted interventions. Serotonin is one of the essential neurotransmitters involved in the propagation of pain signals through both ascending and descending pathways, acting via various receptor subtypes, including the 5-hydroxytryptamine receptor-6 (5-HT6R) [...]

by Rotem Arieli  , Gina Lee  , Yeon ji Ryou  and Peter Martin

Received: 01 July 2022;  Published: 14 November 2022;  doi: 10.21926/obm.geriatr.2204211

This research aims to examine cross-sectional and longitudinal associations of positive subjective well-being among centenarians and near-centenarians in the Health and Retirement Study. Participants who eventually survived to age 98 or older (N = 516) were included. Study variables included demographic characteristics, health and activities of daily living (ADL) functioning, cognitive functioning, and positive well-being. Additionally, a smaller subsample (n = 192) of participants with supplemental leave-behind qu [...]