by Jacob G. Monroe  , Elizabeth Ramsey Bolton  and Emily Zechman Berglund

Received: 14 June 2022;  Published: 02 February 2023;  doi: 10.21926/aeer.2301017

The diffusion of distributed energy resources can overcome some challenges associated with the historical centralized model of electric power distribution. Decentralized generation by residential solar photovoltaic cells creates the potential for peer-to-peer (P2P) electricity trading, where households can act as consumers and prosumers to buy and sell renewable electricity. P2P energy markets are emerging at locations across the globe, and market performance is affected by various social, economic, and environment [...]

by Igor Val Danilov

Received: 20 June 2023;  Published: 05 October 2023;  doi: 10.21926/obm.neurobiol.2304185

The theoretical article aims to develop knowledge about the modulation of shared intentionality at the cellular level. A hypothesis about the neurobiological processes during shared intentionality argues that this pre-perceptual communication occurs through nonlocal neuronal coupling in an ecosystem that can be described as the mother-fetus communication model. The current theoretical study analyses literature to discuss recent findings on the effect of oscillations on neuronal temporal coordination to verify wheth [...]

by Nora B. Henrikson  , Paula R. Blasi  , Marlaine Figueroa Gray  , Lorella Palazzo  , Aaron Scrol  and Stephanie M. Fullerton

Received: 09 August 2022;  Published: 31 October 2022;  doi: 10.21926/obm.genet.2204167

People choose how and if to generate and disclose not just personal genomic data, but also multiple other types of personal health and non-health related data. To contextualize choices about genetic testing and genetic data disclosure, we explored perspectives of genomic data privacy and disclosure compared to other types of data. We conducted a qualitative focus group study with adult members of an integrated U.S. health system, using administrative data to stratify our sample by age and by race/ethnicity. Discuss [...]

by Holly Hazlett-Stevens

Received: 26 July 2021;  Published: 23 November 2021;  doi: 10.21926/obm.icm.2104049

Mindfulness-Based Stress Reduction (MBSR) is an evidence-based health education program for medical patients with a variety of chronic conditions. MBSR also benefits health care providers themselves, decreasing work-related stress and preventing burnout. The objectives of this study were to describe an abbreviated MBSR curriculum developed for health care providers and to present initial program evaluation data assessing acceptability and outcomes. This program was implemented outside the research context with an o [...]

by Maddaloni Valeria  , D'Arco Daniela  , Morano Francesca  , Pepe Nicola  and Atripaldi Luigi

Received: 30 May 2018;  Published: 12 November 2018;  doi: 10.21926/obm.genet.1804048

Infectious diseases are one of the most important causes of morbidity and mortality around the world and have a substantial impact on the health of communities. These diseases are caused by pathogenic microorganisms, such as bacteria, viruses, parasites and fungi. The antibiotics that are currently available are generally considered to be safe and well-tolerated. However antimicrobial resistance is an increasingly serious concern in the treatment of infectious diseases. An understanding of epigenetics now contribut [...]

by Sean A. Hebert  , Aleksandra M. De Golovine  , Rita D. Swinford  , Cynthia S. Bell  , Karen J. Vigil  and Sonal Bhatnagar

Received: 30 June 2018;  Published: 14 August 2018;  doi: 10.21926/obm.transplant.1803017

Background: Human Papilloma virus (HPV) infections are an increasingly concerning etiology for post-transplantation viral-related malignancies. The nonavalent HPV vaccine (Gardasil 9) affords transplant recipients the best opportunity for malignancy prevention, but vaccine uptake remains low. Not previously reported for solid organ transplant recipients, we studied influential factors for HPV vaccine non-initiation. Methods: This survey, conducted from May to December 2017, examined influential factors for HPV vacc [...]

by Vanessa G. Oliveira  , Ana Filipa Saraiva  , Fátima Costa  and Aida Botelho de Sousa

Received: 27 February 2019;  Published: 24 September 2019;  doi: 10.21926/obm.transplant.1903086

Nowadays, hematopoietic stem cell transplantation (HSCT) is a common procedure in hematology units within reference centers, mainly for the treatment of hematological malignancies such as multiple myeloma, lymphoma, and acute leukemia. Nevertheless, HSCT has much wider applications, namely in autoimmune diseases, congenital metabolic defects, and hemoglobinopathies. Thalassemia major and sickle cell disease make up the most frequent hereditary hemoglobinopathies worldwide. Despite advances on the prevention and tre [...]

by Onix Cantres-Fonseca  , Shambhu Aryal  , Christopher King  and Steven D. Nathan

Received: 25 May 2023;  Published: 20 February 2024;  doi: 10.21926/obm.transplant.2401207

Chronic allograft dysfunction (CLAD) is one of the leading causes of death after lung transplantation [1]. CLAD is a progressive and irreversible decline in lung function after transplant, manifested as an obstructive, restrictive, or mixed ventilatory impairment without any identifiable etiology as infection or acute rejection. Multiple risk factors have been associated with this condition. Despite its significant effect on the mortality of transplanted patients, there is still a lack of powerfully effective thera [...]

by Elisabeth Goad

Received: 06 March 2022;  Published: 04 January 2023;  doi: 10.21926/obm.icm.2301002

Compassion-Focused Therapy is an integrative therapeutic model with a wealth of evidence behind its efficacy. Its accessibility leads it to be a helpful therapeutic modality for the intellectual disability population. Its ability to aid the understanding of the person, us as clinicians, and the wider context around us give a depth of understanding not prioritised across all therapeutic models. This article explores Compassion-Focused Therapy in the context of working alongside people with intellectual disabilities. [...]

by Andrew Williams  and Murray Thomson

Received: 09 November 2022;  Published: 09 January 2023;  doi: 10.21926/jept.2301003

This paper examines the economic case for the UK to proceed urgently with the installation of thermal insulation and heat pumps in most UK buildings, in the context of the legal requirement to achieve net-zero carbon emissions by 2050. A recent study by the same authors assumed that such insulation and heat pumps would be in place, and showed how the whole of the UK’s energy demand could be met by low carbon electricity generation and appropriate storage. This paper extends the modelling to consider the risk that i [...]

by Sri Desfita  , Denai Wahyuni  , Yusmarini Yusmarini  , Usman Pato  and Grazyna Budryn

Received: 09 April 2024;  Published: 23 August 2024;  doi: 10.21926/rpn.2403012

This systematic review aimed to analyze the in vivo study of the anti-osteoporotic activity of chickpeas. A comprehensive search for English language papers published between January 2013 and December 2023 using the keywords chickpea or Cicer arietinum, anti-osteoporotic activity or anti-osteoporotic effect, chickpeas and anti-osteoporotic activity, Cicer arietinum and antiosteoporotic activity and their synonyms yielded 3566 results from PubMed, ScienceDirect, SpringerLink and Google Scholar. Articles were screene [...]

by Mahmood Haji-Rahimi  , Kiana Bahmanzad  and Hamed Ghaderzadeh

Received: 06 August 2024;  Published: 31 October 2024;  doi: 10.21926/aeer.2404022

Current production and distribution models in agriculture primarily operate based on the 'linear economy' approach. This means that after the exploitation of natural resources and the production of the final product, a significant portion of these resources and products, now contaminated or turned into waste, exit the economic cycle. The circular economy approach in agriculture seeks to reuse waste products and depleted inputs, thereby reducing the intensity of resource exploitation and taking a step towards sustai [...]

by Livinus Emebiri

Received: 18 August 2023;  Published: 24 November 2023;  doi: 10.21926/rpn.2304023

Wheat (Triticum aestivum L.) is pivotal to global food security, with its energy-rich grains that are also the major vegetable protein source in human diets. Decades of primary emphasis on grain yield improvement have delivered increased gains worldwide, but the grain protein content has declined. Since amino acids are biosynthetic precursors of proteins, this research hypothesized that their contents in the wholegrain flour have also been impacted by past wheat breeding. To test this, the free amino acid content o [...]

by Joseph S. D'Arrigo

Received: 26 December 2019;  Published: 28 February 2020;  doi: 10.21926/obm.geriatr.2001110

Aging, hypertension, diabetes, obesity, atherosclerosis, traumatic brain injury, and other factors can all synergistically promote diverse pathological mechanisms. These risk factors trigger widespread inflammation and oxidative stress, both of which can lead to blood-brain barrier (BBB) disruption. These pathological cascades lead to neuronal Ca2+ increase, neurodegeneration, gradual cognitive/memory decline, and eventually Alzheimer's disease. In particular, more recent research indicates that chronic inflamm [...]

by Nicola Cantasano

Received: 12 June 2022;  Published: 05 January 2023;  doi: 10.21926/aeer.2301003

Posidonia oceanica (Linnaeus) Delile is one of the most important endemic species of the Mediterranean Sea. The long phylogenetic pathway of this species deserves special attention because its evolutionary history allows us to think back over the debated issue of life evolution on Earth. Hence, this marine plant, by terrestrial origin, was born from an ancient ancestor named Posidonia cretacea Hosius & Von der Marck. This seagrass species, currently extinct, lived in the coastal waters of the Tethys Ocean about [...]

by Kesiena Owebor  , Smith Orode Otuagoma  , Ogheneakpobo Jonathan Eyenubo  , Arthur Gogo Uranta  , Friday Erhimudia Ukrakpor  , Kesiena Ezewu  and Ebimene Ezekiel Ebisine

Received: 01 August 2023;  Published: 08 November 2023;  doi: 10.21926/jept.2304033

The proper management of sawdust is critical to socioeconomic development. In this research, waste-to-energy has been proposed to utilize sawdust in selected timber markets in Port Harcourt, namely, Illoabuchi Timber Market, Marine Base Timber Market, and Mile 3 Timber Market. A quantitative approach has been taken to estimate the sawdust generation, energy potential, power generation capacities, and pollutant reduction of indiscriminate combustion of sawdust. The findings suggest that, annually, 171 ktons, 42 kton [...]

by Navya Uppu  , Kelly McMahen  , Tasneem Khasru  and Mark A. DeCoster

Received: 02 August 2022;  Published: 17 October 2022;  doi: 10.21926/rpm.2204020

Green synthesis of nanomaterials endeavors to reduce the use of high energy methods with those that may include lower temperatures and pressures, use of natural products, and bottom-up self-assembly. Here we describe the generation of metal-organic biohybrids (MOBs) with nanoscale features synthesized at physiological (37°C) and room temperature (25°C). These MOBs utilized the naturally occurring amino acid dimer cystine as the biological component, and a series of metals, including copper, silver, and cobalt. The [...]

by Victoria Gómez-Dos-Santos  , Vital Hevia-Palacios  , María Laura García-Bermejo  , Alberto Alcázar-González  , Miren Edurne Ramos-Muñoz  , Laura Salinas-Muñoz  , Elisa Conde-Moreno  , Alejandro Escobar-Peso  , Ana Belén Serrano-Romero  , Ana Saiz-González  , Miriam Menacho-Román  and Francisco Javier Burgos-Revilla

Received: 22 December 2020;  Published: 10 June 2021;  doi: 10.21926/obm.transplant.2102144

The efficacy and safety of using high concentrations of oxygen during hypothermic machine perfusion (HMP) have not been fully elucidated to date. This study investigated the impact of administering high concentrations of oxygen on renal function during HMP in a porcine donation after circulatory death (DCD), as well as the metabolic and biochemical effects of this method. A randomized nonblinded cohort study was established in a porcine transplant (KT) model mimicking Maastricht type III DCD under oxygen-supplement [...]

by Michael Fossel

Received: 11 December 2016;  Published: 06 January 2017;  doi: 10.21926/obm.geriatr.1701001

Geriatrics, and much of clinical medicine, is on the verge of a profound transformational shift. Until now, there has been a sharp conceptual divide between diseases which can be readily and effectively treated, and diseases which we have thought to be beyond clinical intervention. In the first disease category, are many of the most common infections that respond to antibiotics and immunizations. We have made dramatic changes in the demographics and the mortality of many such treatable diseases. At the other extrem [...]

by Scott A. Campbell  , Matthew Hubert  , Janyne Johnson  , Nicole Salamon  and Peter E. Light

Received: 12 March 2019;  Published: 26 June 2019;  doi: 10.21926/obm.transplant.1902069

Background: One of the goals of clinical islet transplantation is to achieve a single-donor transplant that is dependent on obtaining enough quality β cell mass from one donor pancreas. Human islets are routinely cultured prior to transplantation, and pro-survival factors such as GLP-1 analogues have been reported to maintain β cell mass and survival. Interestingly, human islets may secrete GLP-1 and they also express the enzyme DPP4 that proteolytically cleaves GLP-1 into an inactive form. The aim of [...]

by Luiz Felipe da M. Rocha  , Leonardo C. Ferreira  , Maria de Fatima V. Marques  , Rodrigo S. Bitzer  and Marco Antônio Chaer Nascimento

Received: 18 May 2022;  Published: 06 July 2022;  doi: 10.21926/cr.2203020

We synthesized and spectroscopically characterized a new heterotrimetallic {Ti2Ni} ethylene (co)polymerization precatalyst containing one (α-diimine)NiBr2 and two (phenoxy-imine)TiCl4 scaffolds. Its calculated structure was investigated at the DFT B3LYP/LACVP** level. Our calculations showed that the titanium(IV) centers were in a slightly distorted trigonal bipyramidal environment, and the average Ti···Ni distance was 8.76 Å. The precatalyst was used for synthesizing polyethylene a [...]

by Brian D. Barkdoll

Received: 26 May 2023;  Published: 21 November 2023;  doi: 10.21926/jept.2304037

Global climate change has necessitated the reduction of GHG emissions. Water distribution system (WDS) pumping adds to these emissions and, therefore, should be reduced. Under electricity hourly cost tariffs, utilities are incentivized to pump during the nighttime hours. This can have a deleterious effect, however, on GHG emissions. To quantify this effect, a modeling study of twelve real WDSs was performed with an electricity tariff. The systems all had the typical tank-level-based pump controls but also time-base [...]

by Andre Cardim de Aguiar  and Soraya Giovanetti El-Deir

Received: 09 May 2022;  Published: 20 September 2022;  doi: 10.21926/aeer.2203034

The presence of shopping malls causes a social, economic, and environmental impact. The bibliometric analysis is a valuable method used to dentify published research papers, and understand historic information published in scientific journals. This method can be used to carry out qualitative and quantitative analyses of scientific production on a specific subject. This analytical method primarily focuses on analyzing the bibliometric study of the solid waste management method used in shopping malls. A small number [...]

by Mark Stoneking

Received: 10 April 2017;  Published: 02 June 2017;  doi: 10.21926/obm.genet.1702004

none, this is an opinion piece

by Girijesh Kumar

Received: 02 December 2024;  Published: 05 December 2024;  doi: 10.21926/cr.2404014

by Joep Geraedts

Received: 13 April 2017;  Published: 26 April 2017;  doi: 10.21926/obm.genet.1702003

Mark Stoneking, who is a member of the Editorial Board of OBM Genetics has written a textbook on molecular anthropology

by Olushola S. Ayanda  , Cecilia C. Oforkansi  , Omolola H. Aremu  , Oluwakemi E. Ogunjemiluyi  , Ololade L. Olowoyeye  and Cecilia O. Akintayo

Received: 26 June 2022;  Published: 25 July 2022;  doi: 10.21926/cr.2203022

In this study, we investigated the degradation of amido black dye in an aqueous solution using ultra-violet (UV) light catalyzed by iron oxide nanoparticles (nano-Fe). The nano-Fe was synthesized by sodium borohydride reduction of ferric chloride solution and was characterized by scanning electron microscopy (SEM), X-ray diffraction (XRD), and X-ray fluorescence spectrophotometry (XRF). The SEM of the nano-Fe showed regular spherical particles, the XRD examination showed a weak and broad peak at Fe (1 1 0), and the [...]

by Myunik Panthi

Received: 25 May 2023;  Published: 01 December 2023;  doi: 10.21926/obm.geriatr.2304259

This article explores the adaptation process of older adults in residential care facilities in New Zealand. Through a phenomenological approach, this study provides clarity on how older adults adjust in residential care despite losses and challenges. Qualitative data on 24 older adults, 6 residential care facilities, and 10 staff were collected. Utilising qualitative software the following were identified: loss, support, acceptance and meaningful support. Initially, the unfamiliar environment and faces, structured [...]

by Ivan V. Maksimovich

Received: 24 July 2021;  Published: 21 October 2021;  doi: 10.21926/obm.icm.2104036

The present research is dedicated to the application of intracerebral laser PBMT for the treatment of the consequences of ischemic stroke. The effectiveness of intracerebral laser PBMT is compared to that of the conservative therapy methods. Recent studies have demonstrated a high potential of laser technology PBMT in the treatment of various ischemic lesions of the brain. A total of 836 patients who had experienced ischemic strokes of different degrees of severity in the period ranging from 6 months to 6 years pri [...]

by Gidon Eshel

Received: 03 August 2020;  Published: 25 December 2020;  doi: 10.21926/aeer.2004005

Environmentally motivated voluntary diet modifications are the focus of much research and public discourse. Yet the nuanced multi-faceted, multi-dimensional nature of agriculture-earth interactions, and limited public environmental knowledge likely combine to undermine the efficacy of environmentally motivated dietary shifts, squandering limited good will. To counter this, here I devise two related indices for crudely estimating importance of various environmental impacts of alternative dietary choices. Based on th [...]

by Michael Chapman  , Jennifer Philip  and Paul Komesaroff

Received: 20 December 2018;  Published: 17 June 2019;  doi: 10.21926/obm.geriatr.1902056

Alzheimer’s Disease is increasingly seen as the major health problem in developed countries supplanting cancer and heart disease. The terror with which we respond to dementia, is grounded in a view of dementia as a monstrous descent, ambushing our healthy ageing through an incursion of pathology. The pervasiveness of this view can mean that other perspectives and even the views of those most touched by the challenges of dementia remain unheard. Part of the cultural conversation around dementia is informed by [...]

by Komeil Mirzaei Baboli  and Sumeet K. Mittal

Received: 29 October 2020;  Published: 05 February 2021;  doi: 10.21926/obm.geriatr.2101157

A 64-year-old, cachectic man with body mass index (BMI)

by Johannah Ruddy  and Kate Scarlata

Received: 05 August 2022;  Published: 13 February 2023;  doi: 10.21926/rpn.2301003

Celiac disease (CD) is a multisystem immune-mediated disorder resulting in enteropathy of the small intestine with the ingestion of gluten, in genetically susceptible individuals. This condition impact 1% of the population and can result in the development of other conditions such as chronic fatigue, anemia, osteoporosis, aphthous stomatitis, elevated liver enzymes, joint pain, infertility, peripheral neuropathy, and epilepsy. In this review, we outline the clinical presentation of CD, the physiological differences [...]

by Poppy L.A. Schoenberg  and Katlyn M. Gonzalez

Received: 27 March 2022;  Published: 05 December 2022;  doi: 10.21926/obm.icm.2204052

The multi-dimensional measurement of complex biological systems and sub-systems is made possible by high-dimensional omics technologies. This frontier of research is promising for elucidating disease processes, physiological parameters, and therapeutic action mechanisms. Omics have potential merit for the integrative medicine field that is relatively early in terms of mechanistic research towards understanding the underlining therapeutic processes of mind-body interventions that show to affect multiple systems simu [...]

by Jeremy M. Quintana  , Alexandra L. Stinchcomb  , Jessica H. Kostyo  , Blair M. Robichaud  , Michael A. Plunk  and Robert R. Kane

Received: 08 October 2018;  Published: 28 December 2018;  doi: 10.21926/obm.transplant.1804036

Islet transplantation has proven to be a viable treatment for individuals suffering from both Type 1 Diabetes Mellitus (T1D) and chronic pancreatitis. However, a variety of challenges limit the effectiveness of this procedure by reducing the number of islets that survive the harvesting and transplantation processes. Increasing islet survival would increase the long-term effectiveness of the procedure and allow this technique to be used in more patients. A number of factors have been shown to improve the outcomes of [...]

by Justin Cole  , Eugene Golts  , Michael Bernales  , Dina Shirazi  , Deepa Kurup  , Sarah Golts  , Gordon Yung  , Aarya Kafi  , Christine M. Lin  , Travis Pollema  and Kamyar Afshar

Received: 19 October 2023;  Published: 08 May 2024;  doi: 10.21926/obm.transplant.2402214

Despite the concerted efforts by lung transplant recipients (LTR) and their medical teams, hospital readmissions are common in the first year following transplantation. Reasons for unplanned readmissions include allograft rejection, infections, and respiratory failure before the SARS-COV-2 pandemic. Clinical predictors of readmissions have changed over time with the higher risk factors of acceptable criteria for recipients and donors. We aimed to assess more recent readmission rates based on group classifications t [...]

by Alison Schmidt  and Anthony Shanks

Received: 16 June 2021;  Published: 27 September 2021;  doi: 10.21926/obm.genet.2103138

Cell-free DNA has emerged as the most reliable, non-invasive prenatal screening tool for fetal aneuploidies. It has come to replace the previously widely used quadruple screen offered in the second trimester of pregnancy. This change comes with improved detection for aneuploidy but also presents potential gaps in prenatal diagnosis including detection of open fetal defects and emerging data on prediction of adverse pregnancy outcomes. This review article provides a historical summary of the quadruple marker screen [...]

by Takeshi Hatta  , Taketoshi Hatta  , Junko Hatta  , Akihiko Iwahara  , Kazumi Fujiwara  , Kimiko Kato  and Yukiharu Hasegawa

Received: 15 October 2021;  Published: 24 February 2022;  doi: 10.21926/obm.geriatr.2201190

In the present study, we identified the factors of cognitive and physical performances predicting self-rated health perception (SRH) using an SRH questionnaire in 660 (298 men and 362 women) upper-middle-aged community dwellers. In addition, neuropsychological test battery and physical ability tests were applied. A multiple regression analysis was conducted using the forced entry method; digit cancellation test (D-CAT1), logical memory test, verbal fluency test, back strength, timed-up and-go (TUG), balancing test, [...]

by Melissa Stock  and Catriona Craig

Received: 20 April 2024;  Published: 14 September 2024;  doi: 10.21926/obm.icm.2403051

‘Personality disorders’ (referred to as complex emotional needs in this report) are common in older adults. Yet they are often under-recognised which impacts access to appropriate care pathways. Once in services, older adults lack the same access to specialist mental health care as adults, and the evidence base in older adults with complex emotional needs is sparse. Compassion Focused Therapy (CFT) is an approach that has shown promise for those with complex emotional needs. This case report presents a 12-session C [...]

by Mats Niklasson  , Irene Niklasson  and Peder Rasmussen

Received: 15 August 2021;  Published: 29 January 2022;  doi: 10.21926/obm.icm.2201005

The aim of this commentary is to present characteristics of an “unidentified psychological barrier,” which we previously have speculated to be associated with vestibular underachievement, an overlooked part for the understanding of the resistance to physical activity as well as in the assessments and interventions of developmental coordination disorder (DCD). Furthermore, we will discuss the importance of its identification and how to push knowledge forward. A delayed or partly absent sensorimotor devel [...]

by Frida Milella  , Davide Donato Russo  and Stefania Bandini

Received: 15 October 2023;  Published: 15 December 2023;  doi: 10.21926/obm.geriatr.2304262

Due to aging demographics, prolonged life expectancy, and chronic diseases, European societies' increasing need for care services has led to a shift towards informal care supplied by family members, friends, or neighbors. However, the progressive decrease in the caregiver-to-patient ratio will result in a significant augmentation in incorporating intelligent aid within general care. This study aimed to build upon the authors' previous systematic literature review on technologies for informal caregivers. Specificall [...]

by Felicity Saunders  , Jane Vosper  , Stuart Gibson  , Rhiann Jamieson  , Jill Zelin  and Janet Barter

Received: 16 October 2021;  Published: 14 April 2022;  doi: 10.21926/obm.icm.2202017

Genito-Pelvic Pain Penetration Disorder (GPPPD) affects between eight and twenty percent of women. There is recent evidence that compassion focused therapy (CFT) can help those with general health conditions and persistent pain. This study aims to investigate application of CFT techniques to an existing psychosexual therapy group of women with GPPPD and establish an effect size that could be used in a fully powered trial in future. The study took place within a routine clinical setting. Women who attended a group w [...]

by Sai Batchu  , Michael Joseph Diaz  , Keldon Lin  , Namrata Arya  , Karan Patel  and Brandon Lucke-Wold

Received: 04 September 2022;  Published: 20 February 2023;  doi: 10.21926/obm.neurobiol.2301157

Pituitary neuroendocrine tumors (PitNETs) are common intracranial tumors comprising numerous subtypes whose metabolic profiles have yet to be fully examined. The present in silico study analyzed single-cell expression profiles from 2311 PitNET cells from various lineages and subtypes to elucidate differences in metabolic activities. Gonadotroph tumors exhibited high activities with histidine metabolism, whose activity is low in lactotroph tumors. Somatotroph tumors enriched for sulfur and tyrosine metabolism, while [...]

by Jose L. Tapia  and Jon Andoni Duñabeitia

Received: 31 March 2023;  Published: 10 October 2023;  doi: 10.21926/obm.neurobiol.2304187

Driving is a critical aspect of personal mobility and autonomy, but ensuring road safety requires a comprehensive evaluation of driving abilities beyond self-reported behaviors and practical skills. This article emphasizes the importance of cognitive assessment in determining fitness to drive and explores the potential benefits of using digital tools for such evaluations to enhance road safety. Implementing these digital tools does come with challenges, such as unfamiliarity with digital cognitive reviews for some [...]

by Anikka M. Swaby  and Luis B. Agellon

Received: 20 December 2021;  Published: 26 May 2022;  doi: 10.21926/rpn.2202014

Microbes have been part of the diet throughout human history. In the evolution of food preservation practices, some techniques inadvertently leveraged microbial activity not only to extend the storage life but also to enhance the properties and nutritive value of foods. In the last century, a variety of bacterial species (referred to as probiotics) were found to confer health benefits to the host. The advent of high-throughput sequencing methods facilitated improved surveillance of conventional probiotics within gu [...]

by Jaclyn B. Murry  and Ying S. Zou

Received: 30 June 2022;  Published: 07 November 2022;  doi: 10.21926/obm.genet.2204168

Double aneuploidy is the co-occurrence of aneuploidy of two different chromosomes within the same individual. Genomic imbalance associated with two aneuploidies in humans is associated with early lethality, and observation in live-born humans is rare. In isolation, trisomy of chromosomes 13, 18, 21, X, and Y may be better tolerated, whereas monosomy of X is the only such type of aberration that may be compatible with life. It is hypothesized that two successive malsegregation events must occur in early development [...]

by James S. Powers  , Destiny O. Birdsong  , Kemberlee R. Bonnet  , Neena R. Kapoor  , Jamaria J. Southward  , Ifeoma Nwankwo  and David G. Schlundt

Received: 25 April 2019;  Published: 26 August 2019;  doi: 10.21926/obm.geriatr.1903072

Background: Narratives encompass written reflection experiences and hold the potential to display valuable insights into trainees’ thinking. We analyzed narratives from graduate students trained in aging themes, who then interviewed older hospitalized adults (senior partners) about their life experiences. Methods: Three Discovery & Learning Fellows trained on open-ended interviewing, empathy, and aging themes performed semi-structured interviews. Senior partners were hospitalized older veterans. After the [...]

by Aniebiet D. Udoh  , Ogheneruona E. Diemuodeke  , Mohammed M. Ojapah  , Fidelis I. Abam  and Joseph C. Ofodu

Received: 29 December 2022;  Published: 13 April 2023;  doi: 10.21926/jept.2302015

The quest to decarbonize the energy space to avert the negative climate change consequences calls for using low/zero-carbon energy conversion technologies in the energy generation space. The Organic Rankine Cycle is a low/zero-carbon energy conversion technology for recovering waste heat from low to medium-temperature heat sources and for biomass conversion. Therefore, this paper presents the thermodynamic optimization, with an artificial bee colony algorithm, of different ORC configurations, including simple organ [...]

by Mason L. Yeh  and Eric S. Levine

Received: 11 April 2017;  Published: 27 April 2017;  doi: 10.21926/obm.neurobiol.1702005

Autism spectrum disorders (ASDs) are diagnosed on the basis of three behavioral features, namely, (1) deficits in social communication, (2) absence or delay in language and (3) stereotypy. The consensus regarding the neurological pathogenesis of ASDs is aberrant synaptogenesis and synapse function. Further, it is now widely accepted that ASD is neurodevelopmental in nature, placing emphasis on derangements occurring at the level of intra- and intercellular signaling during corticogenesis. At present, there is an ev [...]

by Rahul Abhyankar  , Divya Mella  and Edward Pan

Received: 12 November 2018;  Published: 04 January 2019;  doi: 10.21926/obm.neurobiol.1901018

Objective: To report a unique case of cerebellopontine angle glioblastoma with concurrent spinal cord involvement. Background: Glioblastoma (GBM) is the most common primary malignancy of the central nervous system (CNS), comprising 46.6% of all CNS malignancies. By anatomic location, cerebellopontine angle (CPA) GBMs are exceedingly rare. To our knowledge, the following case represents the tenth reported case of CPA GBM and the first with a corresponding spinal cord tumor on presentation. Methods: Retrospective cha [...]