by Girijesh Kumar

Received: 02 December 2024;  Published: 05 December 2024;  doi: 10.21926/cr.2404014

by Tkachuk Elena Anatolyevna  and Kurenkova Galina Vladimirovna

Received: 15 October 2023;  Published: 28 February 2024;  doi: 10.21926/obm.genet.2401218

This work describes a clinical case of a violation of sex formation in a newborn child with Y-chromosome dysomy. The diagnostic challenges related to Y-chromosome variability and associated anomalies in sex development are being considered. The work presents clinical and laboratory data for Y-chromosome dysomy. It is noted that the challenge in diagnosing disorders of sex development is associated with the polymorphic clinical manifestations of this syndrome. It is noted that the presence of Y-chromosome dysomy is [...]

by Robert M. Sullivan  and John P. Hileman

Received: 15 November 2021;  Published: 22 February 2022;  doi: 10.21926/aeer.2201009

Our study sought to identify a regional explanation for declining fertility in stocks of co-occurring salmonids in the upper Trinity River, northern California, USA. We focused on evaluating the relationship between thermal variance in river water and hatchery-measured estimates of female fertility as a function of highly managed annual flow regimes. We evaluated annual and seasonal variation in volume of flow and water temperature in response to managed flows associated with annual in-river restoration actions. We [...]

by Sandra Mikhael  , Maria Shawky  , Gulraiz Hashmi  , Ivan Bernal  and Roger A. Lalancette

Received: 28 June 2020;  Published: 23 July 2020;  doi: 10.21926/acr.2003006

It is historically interesting to note that, whereas the [Co(NH3)6]3+ cation was isolated by Tassaert in 1798 (which he described as the tri-chloride) and that, in the early days of Coordination Chemistry, Jørgensen and Werner isolated many of its other salts, the fluoride was never reported. In fact, in relatively modern times, lack of success was, invariably, the result of attempting its isolation and full characterization. Significantly, there is no entry for its structure in standard sources such as Inorganic C [...]

by Marcus A. Henning  , David Lu  , Lillian Ng  , Frederick Sundram  and Yan Chen

Received: 16 August 2024;  Published: 23 January 2025;  doi: 10.21926/obm.icm.2501007

This scoping review aims to understand the available research and the quality of evidence about the cost-effectiveness of mindfulness-based interventions when applied to the medical student context. There is considerable literature pertaining to the application of mindfulness-based interventions in this context. However, the links between cost and effectiveness need to be established to ensure the relative integrity of these therapeutic systems. The participants included in the study were medical students (undergra [...]

by Deepti Singh Chalia  , Anil Khurana  , Mehul Trivedi  , Pinaken Trivedi  , Sarita Gola  and Parul Singh

Received: 20 February 2023;  Published: 28 June 2023;  doi: 10.21926/obm.icm.2302025

This retrospective data analysis study aims to analyze the data collected during adjunctive homeopathy treatment of COVID-19 patients by the Homoeopathic medical officers (HMO) in Gujarat state-dedicated COVID-19 hospitals (DCH) during the first wave of the pandemic. The HMOs used the standard data collection forms/sheets to record each patient's demographic information, clinical symptoms, homoeopathic management, and outcome data. Data of all cases hospitalized with COVID-19 of any age, and both genders were i [...]

by Kenji Amagai  , Hiroto Kotake  , Masahiro Munemura  , Sawako Shigeto  and Masayuki Horio

Received: 10 October 2022;  Published: 02 February 2023;  doi: 10.21926/jept.2301005

This paper describes the development of low-speed electric community buses (LSECBs) designed by the author's group and their spread situation in Japan. LSECBs are electric vehicles that can travel on public roads at speeds of less than 5.56 m/s (20 km/h). The university, local government, local businesses, and residents with a co-design approach developed the LSECBs. They have various advantages such as safety due to low speed and low energy consumption. In particular, the LSECBs have features not found in ordinary [...]

by Rebecca L. Utz  , Michael Caserta  , Eli Iacob  , Catharine Sparks  , Louisa Stark  , Alexandra Terrill  , Amber Thompson  and Bob Wong

Received: 15 June 2023;  Published: 08 October 2023;  doi: 10.21926/obm.icm.2304040

Dementia caregivers are susceptible to adverse physical and mental health outcomes, given the often prolonged and challenging care and support they provide to family members with Alzheimer’s Disease and Related Dementias (ADRD). This report describes a community-engaged implementation of a novel behavioral intervention - an “app” (interactive website) called TLC (Time for Living and Caring) that coaches caregivers on how to maximize the benefits associated with respite time. The rationale and features of the TLC in [...]

by Srinivasan Periasamy  , Se-Ping Chien  , Chen Hsu  , Dur-Zong Hsu  and Ming-Yie Liu

Received: 10 March 2020;  Published: 18 May 2020;  doi: 10.21926/obm.hg.2002047

Metformin has been widely used as a therapeutic drug for hyperglycemia and diabetes. Sleep is a vital and restorative process that is necessary for the proper functioning of organs. Sleep deprivation can induce multi-organ injury, including damage to the pancreas and liver that may result in hyperglycemia and diabetes. We studied the role of metformin in reversing sleep deprivation-induced hyperglycemia and pancreatic and liver dysfunction in mice. Mice were kept in cages and fed water and food ad libitum. Mice wer [...]

by Layachi Guelmine  and Hadda Hadjab

Received: 27 March 2021;  Published: 09 August 2021;  doi: 10.21926/rpm.2103033

The present study investigated the effect of reused rubber particles (RRP) on the deicer salt durability of ordinary concrete. Four mixtures were designed, a control concrete (CC) and three other rubber concretes obtained by partial substitution of natural dune sand aggregate with reused rubber particles with 0%, 3%, 6%, and 9% w/w. All studied concretes were subjected to the combined effect of freeze/thaw (56 and 120) cycles with the deicer salt solution of 3% NaCl. The results indicated that RRP improved the deic [...]

by Negar Noorbakhsh  , Mina Zamani  , Alireza Sedaghat  , Jawaher Zeighami  , Farangis Foroughi Behbahani  , Sahere Parvas  , Alihossein Saberi  , Mohammad Hamid  , Roya Ghanavati  , Gholamreza Shariati  and Hamid Galehdari

Received: 11 October 2022;  Published: 12 May 2023;  doi: 10.21926/obm.genet.2302181

Familial Mediterranean Fever (FMF) is classified as an autoinflammatory genetic disease inherited by mutations in MEFV. These mutations can affect the dysregulation of inflammatory processes in the human body and lead to fever and pain in the chest and abdomen. Many known missense mutations in MEFV are linked to FMF disease. Mutations in MEFV in most cases are located on the short arm of chromosome 16 and can impair the function of the pyrin protein. In this research, we aimed to examine the entire exons of MEFV fo [...]

by Mieczyslaw Szyszkowicz  and Nicholas de Angelis

Received: 18 September 2021;  Published: 11 February 2022;  doi: 10.21926/aeer.2201005

Air pollution affects various aspects of human health. Here, the associations between the number of emergency department visits for circulatory and respiratory problems and ambient air pollution in Toronto, Canada, in the period between April 2004 and December 2015 were studied. The health data were linked with urban air pollution data and weather factors. The conditional Poisson regression models were built for 18 strata (sex, age group, season), 8 exposure factors (air pollutants, indexes), and their 15 lags (0-1 [...]

by Simona Bassoli  , Anett Schallmey  , Julie Oble  , Giovanni Poli  and Alexandre Pradal

Received: 22 July 2022;  Published: 26 October 2022;  doi: 10.21926/cr.2204036

A two-step protocol for the synthesis of aryl-3-hydroxypropanones, which were regarded as lignin degradation products, was proposed herein. This protocol provided a more rapid and easier access to aryl-3-hydroxypropanones, and aryl-3-hydroxypropanones were expected to be ideal platform molecules for the synthesis of more complex value-added targets.

by Jessica Lum  and Sherif B. Mossad

Received: 26 October 2018;  Published: 14 February 2019;  doi: 10.21926/obm.transplant.1901050

Despite the advances that have been made in the field of solid organ transplant (SOT), organ shortage remains a persistent problem. In addition, the donor pool has been changing with the ongoing opioid epidemic and increase in deaths related to drug overdose each year. More donors are meeting the 2013 United States (U.S.) Public Health Service criteria for increased risk donors (IRDs), or donors who are at higher risk for transmission of Human Immunodeficiency Virus (HIV), Hepatitis C virus (HCV), and other multidr [...]

by Seria Tsan  , Stefanie Kankel  , Niklas Padutsch  , Luisa Person  , Monika Ziegler  , Ahmed Al-Rikabi  , Anja Weise  , Kristin Mrasek  and Thomas Liehr

Received: 16 April 2021;  Published: 25 August 2021;  doi: 10.21926/obm.genet.2103135

Cryptic balanced chromosomal aberrations can be an underlying cause of infertility. In 2003 Cockwell and coworkers highlighted the relevance of euchromatic pericentric regions of acrocentric chromosomes that may be a yet ignored genomic region hosting cryptic rearrangements. Here we offer the first follow-up study to further explore this idea. Two specific molecular cytogenetic probe sets were established to elucidate such cryptic rearrangements together with chromosomal heteromorphisms of acrocentric centromeres. [...]

by Darcy A Hille  , Sverre E Kjeldsen  , Stevo Julius  , Kristian Wachtell  , Peter M Okin  and Richard B Devereux

Received: 30 December 2021;  Published: 24 February 2022;  doi: 10.21926/obm.geriatr.2201189

We aimed to assess some readily available patient characteristics such as urinary albumin excretion as predictors of a primary composite event of myocardial infarction, cerebral stroke, and cardiovascular death among patients with hypertension and left ventricular hypertrophy, and develop risk algorithms for the outcomes. A “Cox proportional hazards” model identified the baseline variables that significantly affected the occurrence of the composite endpoint in 9193 elderly hypertensive patients with lef [...]

by Andreea L. Seritan

Received: 26 November 2021;  Published: 24 January 2022;  doi: 10.21926/obm.geriatr.2201187

Older adults’ mental health needs significantly increased during the COVID-19 pandemic. Geriatric psychiatry is an area of extreme workforce shortage globally. A novel curriculum was developed to educate healthcare providers on COVID-19-related geriatric and geropsychiatry topics. Monthly lectures were presented from November 2020 to June 2021. Evaluations were collected after each lecture via an anonymous survey. Overall lecture quality and relevance for the participants’ clinical practices were rated on a 1-3 Lik [...]

by Vjollca Ndreu  , Yllka Themeli  , Ilirjana Zekja  and Fatjona Kamberi

Received: 02 April 2022;  Published: 06 July 2022;  doi: 10.21926/obm.neurobiol.2203126

The World Health Organization declared the COVID-19 pandemic on March 11th, 2020. The pandemic had significantly affected public health, and the mental health of people was compromised regardless of age or socioeconomic status. In this study, we measured the psychological distress caused by the pandemic and determined the associated factors. An online survey was conducted from November 16th (2020) to January 31st (2021). The participants were Albanian adults (≥18 years old). The call to participate was poste [...]

by Louise O’Hare  and Robyn Griffiths

Received: 08 August 2022;  Published: 14 November 2022;  doi: 10.21926/obm.neurobiol.2204145

Although being one of the most common neurological disorders, migraine is commonly misunderstood and misdiagnosed. Current treatments rely on pharmacological approaches, which have been shown not to be effective for all, and so alternative, non-invasive treatments are being sought. Transcranial stimulation could be a possible treatment for migraine. Transcranial electrical stimulation generally involves applying a current to the cortex via the scalp. Whilst this has previously been mostly done in clinical settings, [...]

by Lara T. C. Mota  , Igor M. Figueredo  , F. Murilo T. Luna  , Rodrigo S. Vieira  , Célio L. Cavalcante Jr.  and M. Alexsandra S. Rios

Received: 26 September 2022;  Published: 22 December 2022;  doi: 10.21926/jept.2204042

In this study, the oxidative stability of the cottonseed oil biodiesel (CB) and soybean oil biodiesel (SB) was investigated by two methodologies, Rancimat and Differential Scanning Calorimetry (DSC), using samples fresh and aged (mid-term storage condition (100 days)). The biodiesel samples were synthesized by transesterification and characterized by specific mass, kinematic viscosity, acidity value, ester content, viscosity index, and peroxide value. The activation energy (Ea), Arrhenius pre-exponential factor (Z) [...]

by Otto V.M. Bueno  , Miguel A. San-Miguel  and Edison Z. da Silva

Received: 10 October 2022;  Published: 14 December 2022;  doi: 10.21926/cr.2204043

Linear atomic chain (LAC) gold nanowires (Au-NWs) containing oxygen impurities are materials that could be used as supports to stimulate chemical reactions. Its peculiar structural characteristics, such as abnormal Au-Au bonds, make it interesting to explore the chemical reactions of this material at a theoretical level. This work investigated the chemical reaction of ethanol supported on Au-NW containing two oxygen impurities. Using ab initio molecular dynamics simulations, it was shown that the presence of oxygen [...]

by Hofit Edna Mashiah  and Susana Pendzik

Received: 25 May 2023;  Published: 11 July 2023;  doi: 10.21926/obm.icm.2303027

This paper follows a preliminary study that examined how 6 (n = 6) creative arts therapists (3 art therapists and 3 drama therapists) coped with the transition to remote therapy in schools during the first lockdown in Israel due to the Coronavirus pandemic. The preliminary research explored the therapists’ experiences and views about working online upon returning to regular in-person meetings. The current paper adds a follow-up interview examining their perspective on this period, two years later. The 1st set of in [...]

by Antonela G. Garzón  , Micaela Albarracín  and Silvina R. Drago

Received: 08 May 2023;  Published: 22 August 2023;  doi: 10.21926/rpn.2303013

Sorghum-based beverages were developed and the effects of decortication on nutritional composition and biofunctional properties after a simulated gastrointestinal digestion were analyzed. For that, white sorghum flours from whole (WS) and decorticated (DS) grains were obtained and used to prepare sorghum beverages. They were analyzed regarding chemical composition, minerals, and phenolic acid contents. Moreover, the bioaccessibility of phenolics, proteins, and the potential bioactivity (ABTS+ scavenging, ACE-I inhi [...]

by Alyson Holland  and Amanda Lorbergs

Received: 29 October 2019;  Published: 12 December 2019;  doi: 10.21926/obm.geriatr.1904093

Beliefs about the daily experience of a disease are used to identify risk and motivate participation in prevention. For osteoporosis, a disease that is affected by health behaviours throughout the lifecourse, individual perceptions of the disease can affect health decisions and future disease prevalence. Understanding how the experience of osteoporosis is perceived by women at different stages of life can illuminate factors that influence engagement in prevention. Women representing three life stages - young adults [...]

by Albena Staynova  , Ljubomira Hadjiiska  , Valeria Hadjidekova  and Rositsa Hristova

Received: 14 August 2018;  Published: 22 October 2018;  doi: 10.21926/obm.genet.1804043

Background: The purpose of study was to assess the cytogenetic effect of chronic low dose radiation exposure of nuclear power plant workers using the micronucleus centromere assay. This method allows the differentiation between centromere-positive micronuclei containing whole chromosome and centromere-negative micronuclei containing acentric fragment pointing to clastogenic action of ionizing radiation. Methods: The effect of low dose occupational exposure was estimated in 32 nuclear power plant workers using in si [...]