by Emma Larsen  , Simon Ghanat  and Scott Curtis

Received: 11 February 2022;  Published: 07 May 2022;  doi: 10.21926/aeer.2202020

The urban heat island (UHI) effect is not well understood, especially within the cityscape. This editorial is from the perspective of an undergraduate student Cadet Emma Larsen, as she comes to understand the UHI through mentorship from professors Simon Ghanat and Scott Curtis, personal experiences as a cadet at a military academy in Charleston, SC, USA, and active learning through participation in a national heat observation campaign, the NOAA HeatWatch, and related independent research. HeatWatch seeks to underst [...]

by Ivan M. Lang

Received: 17 August 2020;  Published: 02 November 2020;  doi: 10.21926/obm.hg.2004052

Several digestive tract reflexes involving the esophagus and its sphincter muscles have been identified, but to date, no comprehensive review has addressed most of these reflexes. The current review presents the known physiology of different esophageal reflexes in which either the esophagus or its sensory or motor portion of the reflex response is elaborated. The current review comprehensively examines the known and possible mechanisms underlying major esophageal reflexes, highlights the huge gaps in current knowle [...]

by Michael Fossel

Received: 12 December 2017;  Published: 24 December 2017;  doi: 10.21926/obm.geriatr.1704003

by Sean J. O’Sullivan

Received: 17 June 2021;  Published: 17 November 2021;  doi: 10.21926/obm.genet.2104143

Advances in clinical psychiatry have been less than hoped for relative to the achievements in neuroscience. However, developments in neuromodulation and psychedelic therapy are promising. The efficacy of such treatments and canonical pharmacotherapies benefit from genetics and personalized medicine. Moreover, recent studies on the perturbation of transcription, including chromatin remodeling, in mental illness emphasized the importance of single-cell qPCR as an investigatory method that bolstered psychiatry. This t [...]

by Anita Modi  and Sherif Beniameen Mossad

Received: 07 July 2019;  Published: 06 September 2019;  doi: 10.21926/obm.transplant.1903085

Chronic inflammatory states lead to T cell exhaustion, characterized by reduced T cell proliferation and activity. Immune checkpoint inhibitors (ICPI) reactivate T cells to restore the immune system’s natural defenses against foreign antigens. The widespread use of these agents in the treatment of malignancy has led to markedly reduced tumor burden and improved patient survival, sparking curiosity about their potential role in the treatment of other chronic inflammatory states, including infectious diseases. While [...]

by Peter Lechleitner

Received: 02 March 2018;  Published: 25 April 2019;  doi: 10.21926/obm.icm.1902027

The first part of this position paper focuses on the debate about the scientific status of homeopathy and presents some answers. The scientific debate however, does not represent the available scientific evidence, which actually supports our limited data. Thus, it seems important and we aim to present how homeopathy can be part of an integrated concept in cancer care and how this is approved by randomized controlled trials. We present some arguments which were helpful to us in the discussion with oncologists that d [...]

by M. Lourdes Mourelle  and Leonel Pereira

Received: 26 January 2025;  Published: 17 April 2025;  doi: 10.21926/obm.geriatr.2502308

The increasing consumer demand for cosmetic products has led to the widespread use of synthetic substances, which are inexpensive and readily available but can sometimes harm the skin and body. Examples include hydroxybenzoic acid esters (parabens) and phthalates, which are considered endocrine disruptors, and synthetic fragrances that may cause irritation or allergies. Consequently, there has been a shift in consumer preferences towards natural cosmetic products. In response to this demand and the expanding market [...]

by Naylya Djumaeva  , Gulnara Akhundjanova  , Leyla Djumaeva  and Dilbar Urunova

Received: 08 October 2023;  Published: 16 January 2024;  doi: 10.21926/obm.icm.2401010

Long COVID syndrome resulting from SARS-CoV-2 infection has a prevalence of 10%-35% in the population. Numerous studies of the disease are currently being conducted concerning the manifestations of long COVID syndrome; however, there are no data on the use of electroacupuncture diagnosis (EAV) and medicament testing (MT) in assessing this condition. The purpose of the study was to study the possibilities of diagnosing EAV to determine changes in the electrodermal activity of acupuncture points of the meridian test [...]

by Suresh Keshavamurthy  and Cody Russell

Received: 11 January 2023;  Published: 04 April 2023;  doi: 10.21926/obm.transplant.2302179

A boundless spectrum of chronic lung diseases is said to effect over 500 million persons globally. Lung transplantation is a well-established therapeutic option for patients suffering from end-stage lung diseases, however waitlist mortality and primary graft failure remain major determinants as post-transplantation 5-year survival is just above 50 percent. Recent innovations in lung transplantation have been aimed at increasing organ availability, improving allograft quality, function, and longevity. Ex-vivo Lung P [...]

by Assaf Assis  , Lena Sapozhnikov  , Sandra Camargo  and Eduardo Mitrani

Received: 07 May 2019;  Published: 14 August 2019;  doi: 10.21926/obm.transplant.1903078

Background: Cell encapsulation technology is most likely the ultimate solution for cell therapy based clinical approaches. A key issue when developing a functional encapsulated construct is to consider not only the nature of the capsule but also how the cells should be incorporated into the capsule in order to minimally compromise their function. Methods: We have developed a tissue engineering approach, composed of decellularized micro scaffolds and various types of cells in which fully functional "Engineered Micro [...]

by Rhythm Joshi  , Zehva Khan  , Aakriti Garg  , Nidhi  , Ubada Aqeel  , Dinesh Bhurani  and Mohd.Ashif Khan

Received: 30 September 2022;  Published: 25 April 2023;  doi: 10.21926/obm.transplant.2302183

Hematopoietic stem cell transplantation (HSCT) or Bone Marrow Transplantation (BMT) has significantly improved the survival rates of patients suffering from hematological malignancies. However, the cure can only be achieved at the price of morbidity and long-term complications such as bone diseases leading to fractures and osteopenia. Several studies have reported the impact of organ transplants on bone metabolism, electrolytes and blood profile. This prospective observational clinical study aims at elucidating the [...]

by Laura Borth  and Meredith Ponder Whitmire

Received: 31 March 2023;  Published: 17 August 2023;  doi: 10.21926/obm.geriatr.2303246

Malnutrition is a problem that is often not identified in hospitals as 8% of hospital patients are diagnosed but malnutrition is estimated to affect 20-50% of patients. Federal programs such as Joint Commission accreditation and the new, optional, global malnutrition composite score from CMS may improve inpatient malnutrition diagnosis, but there may be an opportunity to do more from a regulatory side. It’s unknown how many states are considering malnutrition from this standpoint. The study’s goal was t [...]

by Federica Odaldi  , Vanessa De Pace  , Giacomo Frascaroli  , Giuliana Germinario  , Giorgia Comai  , Francesco Vasuri  , Gaetano La Manna  and Matteo Ravaioli

Received: 22 November 2019;  Published: 03 February 2020;  doi: 10.21926/obm.transplant.2001096

Donation after circulatory death (DCD) is an increasingly used resource to alleviate chronic renal graft shortages. Organs from donors with progressively increased creatinine levels due to acute kidney injury are used, but the effects of this condition on kidney transplantation are still unclear. Ex-situ machine perfusion is emerging as a potential tool to preserve and resuscitate vulnerable grafts. We report a case of DCD kidneys discarded due to severe acute kidney injury with favorable histological Karpinski sco [...]

by Emma Maloney  , Clodagh Dowling  , Tara Deehan  and Gary O' Reilly

Received: 29 July 2022;  Published: 18 November 2022;  doi: 10.21926/obm.icm.2204051

To compare client response to a 3-stage phased intervention for complex trauma, comparing (1) those who received face-to-face intervention with (2) those who received a hybrid of face-to-face moving mid-therapy to online intervention with (3) those who received online only. Comparing quantitative and qualitative outcome data from 3 consecutive groups (N=22) who participated in a 3-stage phased intervention for complex trauma (1) face-to-face intervention (n=7); (2) a mix of face-to-face and online intervention (n=6 [...]

by Harnish P Patel  , Faidra Laskou  and Elaine M Dennison

Received: 15 February 2024;  Published: 23 January 2025;  doi: 10.21926/obm.geriatr.2501296

Sarcopenia is characterised by progressive and generalised decline in muscle strength, function, and muscle mass. Now recognised as a muscle disease, it is highly prevalent in older adults, with estimates of up to 30% in some populations. Sarcopenia has a complex multifactorial aetiology, including cellular and molecular changes, chronic disease, lower physical activity as well as nutritional deficiency. Sarcopenia is associated with a range of adverse physical and metabolic outcomes leading to disability, morbidit [...]

by Mauro Turrin  , Lucia Fornasiero  and Antonio Navarro

Received: 08 January 2023;  Published: 27 June 2023;  doi: 10.21926/obm.geriatr.2302240

We describe the clinical case of a 74-year-old male patient who received the second Comirnaty/Pfizer anti-COVID-19 vaccine dose. After 3 weeks he showed the clinical signs of polymyalgia rheumatica. The history included mild chronic normocytic normochromic anemia and hypogammaglobulinemia, osteoarthritis disease, livedo reticularis, hypercholesterolemia, and arterial hypertension. Despite prolonged treatment with NSAIDs and dexamethasone, the disease evolved into remitting seronegative symmetrical synovitis with pi [...]

by Jeggathishwaran Panisilvam  , Peng Cheng Wang  and Hui An

Received: 26 March 2022;  Published: 13 July 2022;  doi: 10.21926/jept.2203024

Reducing and conserving fuel usage is pivotal for any engineering system for the development of a sustainable energy solution. Proton exchange membrane fuel cells (PEMFCs) are one of the promising renewable energy systems that consume hydrogen as their source of fuel to generate electricity. This paper investigate the necessity of the constant supply of fuel (hydrogen) in the PEMFC system to ensure stable operation. We propose that a dynamic supply of fuel could help achieve similar performance and reduce the amoun [...]

by Richard Cheng  and Jon Kobashigawa

Received: 23 January 2019;  Published: 09 April 2019;  doi: 10.21926/obm.transplant.1902061

Cardiac allograft vasculopathy (CAV) limits long-term survival after heart transplantation. CAV with discrete or tubular lesions can be treated with percutaneous coronary intervention (PCI) with high procedural success. Revascularization with balloon angioplasty, bare-metal stents, and first-generation drug-eluting stents has been associated with high and unacceptable restenosis rates. However, second-generation drug-eluting stents are associated with favorable stent and lesion patency. Stent and lesion patency now [...]

by Kurt Grüngreiff  , Thomas Gottstein  and Dirk Reinhold

Received: 15 March 2019;  Published: 13 June 2019;  doi: 10.21926/obm.hg.1902023

Acute and in particular chronic liver disease of viral, alcoholic and non-alcoholic genesis is a large, often unnoticed health hazard around the world. It can lead to cirrhosis and hepatocellular carcinoma (HCC) in the course of decades. Liver fibrosis, conversion of functional parenchyma to connective tissue (scar tissue) as a consequence of chronic liver damage, is a connecting pathogenic process in all chronic liver diseases. Zinc is an essential micronutrient in human health, playing a fundamental role in cellu [...]

by Kazuyuki Suzuki  , Akinobu Kato  and Yasuhiro Takikawa

Received: 04 February 2019;  Published: 16 July 2019;  doi: 10.21926/obm.hg.1903027

Hepatic encephalopathy (HE) is a neuropsychiatric syndrome showing a wide spectrum and one of the serious complications seen in patients with acute and chronic liver disease or spontaneous portal-systemic shunting. Recently, HE has been classified into two categories: covert HE, which involves minimal HE and is identified solely through psychometric or neurological tests, and overt HE (coma grade II-IV). Although recent therapies based on evidence-based results have improved the therapeutic outcomes of HE patients, [...]

by Giorgos Mountrakis  and Sheng Yang

Received: 24 March 2021;  Published: 26 October 2021;  doi: 10.21926/aeer.2104026

While numerous studies have considered forest loss factors at local scales, there is a gap of comparative quantitative regional modeling at the U.S. national level. Here, we investigated statistical relationships between gross forest cover loss (GFCL) and numerous socioeconomic, biophysical and ownership variables between two decades, the 1990s and the 2000s. A spatial error model was employed to compensate for spatial autocorrelation effects. Models from the 2000s had stronger explanatory power than the 1990s mode [...]

by Antoine Buemi  , Jérôme Duisit  , Flora Musuamba  , Tom Darius  , Martine De Meyer  , Selda Aydin  , Nada Kanaan  , Arnaud Devresse  , Eric Goffin  and Michel Mourad

Received: 13 January 2020;  Published: 13 May 2020;  doi: 10.21926/obm.transplant.2002109

This study aimed to investigate the outcomes of transplantation from donors aged less than three years in a single-center consecutive series. A total of 52 en bloc kidney graft transplantations were performed. In 22 cases, organs were procured from donors aged less than one year (group 1). In 30 cases, the age of donors varied from one to three years (group 2). After transplantation, renal function and graft and patient survival were evaluated retrospectively. No significant difference was observed between the grou [...]

by Morgan A. Valley  and Lorann Stallones

Received: 30 June 2021;  Published: 12 September 2021;  doi: 10.21926/obm.icm.2103029

Hospice care workers are exposed to the hazards associated with in-home care in uncontrollable environments as well as occupational stress related to caring for terminally ill patients and their families. This study aimed to assess the effectiveness of an abbreviated mindfulness intervention to improve hospice care worker occupational safety performance and well-being. This study used a single-group pre-post design to pilot test an 18-hour mindfulness training as an intervention on self-reported safety performance [...]

by Laila Midhat  , Naaila Ouazzani  , Abdessamed Hejjaj  , Ahmed Ouhammou  and Laila Mandi

Received: 29 December 2020;  Published: 22 July 2021;  doi: 10.21926/rpm.2103030

This study aimed to assess the effectiveness of the phytostabilization ability of the native Moroccan plant Citrullus colocynthis on the neutralization of soil acidity and stabilization of metallic trace elements (MTEs) assisted by marble waste. Mine tailings (MT) collected from an abandoned polymetallic site were mixed with powdered marble (PM) using different mixing ratios (%): (MTPM25), (MTPM50), (MTPM75), and agricultural soil (AS) acting as the control. Seeds of C. colocynthis were selected and planted under g [...]

by Bhabani Shankar Mohanta  , Rita Das  and Nigamananda Das

Received: 21 December 2022;  Published: 13 October 2023;  doi: 10.21926/cr.2304025

Tungstophosphate (PW12O403-) intercalated ZnAl-Layered double hydroxide (ZnAl-PW12) was successfully synthesized through the rehydration of calcined LDH. Chemical analyses and characterizations by powder XRD, FT-IR, and Diffuse reflectance UV-Vis spectra confirmed the intercalation of PW12O403- ions equivalent to ~80% of the residual positive charge in the brucite layer. The efficiency of ZnAl-PW12 for decolourisation of four structurally different cationic/anionic dyes through simultaneous adsorption and photocata [...]