by Laura Alonso Canal  , Cecilia Paredes Mercado  , María José Quiles Blanco  and Marco Motta Calderón

Received: 01 April 2019;  Published: 14 May 2019;  doi: 10.21926/obm.neurobiol.1902028

Lyme disease is a spirochetal illness transmitted primarily through the bite of ticks. The disease has a broad spectrum of comorbid conditions including osteoarticular, cardiovascular, and neurological involvement. In addition, clinical variability depends on the age of affected individuals. The Center for Disease Control recognizes the disease as an epidemic and mentions it to be a major morbidity burden in our environment because of the frequent lack of diagnosis and early treatment. Scientific literature mention [...]

by Sabira Sabir Ismayilova  and Sabir Qarsh Amirov

Received: 09 January 2022;  Published: 28 June 2022;  doi: 10.21926/cr.2202017

The kinetics of dearomatization of a kerosene fraction processed using a zeolite catalyst (0.9 HZSM-5) at different temperatures (160-200°C), the molar ratio between the aromatic hydrocarbons present in the kerosene fraction and n-decene (1:(0.5-4)), and the reaction time (1-3 h) were studied. Based on the obtained data, a kinetic model for kerosene dearomatization is proposed. It is assumed that the single-center Riedel mechanism is followed. The stage associated with the interaction between n-decene adsorbed on t [...]

by Jacy C. Downey  and Clinton G. Gudmunson

Received: 19 October 2021;  Published: 29 January 2022;  doi: 10.21926/obm.icm.2201006

Parents model and teach early health practices that persist into adulthood by establishing a family culture through which children learn related family beliefs, values, and expectations. This phenomenological study examined the ways in which a purposefully selected group of mothers (selected due to their high scores on the Family Nutrition and Physical Activity screening tool) shaped family culture related to physical activity, addressed screen-time behaviors, and established positive eating related routines. Findi [...]

by C. Shawn Sun  , Nahid Farzana  , Dinesha Kuruppuarachchi  , Mohammadamin Azimi  and Huayuan Zhong

Received: 10 September 2022;  Published: 04 May 2023;  doi: 10.21926/rpm.2302019

Infrastructure degradation attributable to concrete deterioration and corrosion of reinforcing steel has been a long-standing challenge to the owners and engineers. This problem becomes more evident when concrete structures are subject to aggressively corrosive environments. The use of advanced materials such as ultra-high performance concrete (UHPC) and carbon fiber reinforced polymer (CFRP) bars has a strong potential to overcome this challenge and help build new infrastructure that is durable and sustainable. Ho [...]

by Charles Heriot-Maitland  and Jo Taylor

Received: 22 March 2024;  Published: 11 June 2024;  doi: 10.21926/obm.icm.2402033

This article describes the development and delivery of a novel model of supervision for senior teachers in schools, informed by Compassion Focused Therapy (CFT). It explores whether this model can be considered acceptable and valuable to senior teachers, and is able to be delivered by multiple supervisors using a manual. Surveys, interviews, and focus groups were used to gather feedback about the value and impact of the supervision. Data were gathered from 39 senior teachers across three phases to assess feedback o [...]

by Jacob Ladenburg

Received: 28 April 2020;  Published: 12 August 2020;  doi: 10.21926/jept.2003015

Visual external costs are significant elements in the cost-benefit analysis of wind farm locations. This has been demonstrated well in the literature. However, in the assessment of the visual costs, a large share of the earlier studies used no or only simplistic visualizations of the visual impacts at stake. The cost estimates thus rely on the respondents’ ability to imagine the visual impacts associated with wind turbines of different sizes and at different locations. This has been argued to potentially reduce the [...]

by Mariusz KSIĄŻEK

Received: 24 March 2021;  Published: 15 June 2021;  doi: 10.21926/rpm.2102024

Metal parts of endoprosthesis have a detrimental effect on the bones that come into contact with them and on the entire body of the patient. Coating them with biocompatible layers (hydroxyapatite and bioglass) has not yet brought about permanent results. In this study, the author showed the possibility of using a binder containing sulfur waste for this purpose. The sulfur binder is used industrially in electrical engineering and construction applications. The chemical properties of elemental sulfur indicate that it [...]

by Nicholas J Cook

Received: 14 April 2021;  Published: 25 June 2021;  doi: 10.21926/jept.2102027

A refined and extended version of the Offset Elliptical Normal mixture model has been developed to parameterise the seasonal diurnal wind vector automatically. Automated using R scripts, the method eliminates any potential risk of confirmation bias posed by the manual supervision in the original method. Refinements to the method include the latest algorithms for clustering of Gaussian mixtures, with Bayesian regularisation to set the number of components and to limit the predisposition to overfit. A new extension u [...]

by Olivia L. Pastore  , Michelle S. Fortier  , Leah J. Ferguson  and Shane N. Sweet

Received: 23 August 2023;  Published: 20 December 2023;  doi: 10.21926/obm.icm.2304061

Self-compassion involves being touched by and open to one's own suffering, coupled with the desire to alleviate it and heal oneself with kindness. While self-compassion has gained significant attention in research, certain conceptual and methodological complexities have evolved over time and led to ambiguity surrounding the concept. As such, the overall purpose of this commentary was to highlight and discuss the different perspectives of self-compassion in the literature. We opted to centralize our focus primarily [...]

by Dominic Emerson  , Jon Kobashigawa  , Ryan Levine  , Jamie Moriguchi  , Dominick Megna  , Joshua Chung  , Dany Ramzy  , Alfredo Trento  and Fardad Esmailian

Received: 14 April 2020;  Published: 06 July 2020;  doi: 10.21926/obm.transplant.2003114

In advanced heart failure, orthotopic heart transplantation (OHT) remains the standard for definitive treatment. Patients with heart failure and concomitant pulmonary hypertension (PH) represent a challenging subgroup, with poor outcomes following OHT. Recently, Mechanical Circulatory Support (MCS) devices have been utilized as a bridge to OHT for these patients. Patients with MCS devices who underwent OHT were evaluated at a single center. Patients were stratified into three groups, depending on baseline pulmonary [...]

by Danielle Reilly  , Ibrahim Duyar  , Jackie McBride  and Robert Williams

Received: 09 September 2024;  Published: 24 March 2025;  doi: 10.21926/obm.icm.2501016

The current study explored the adverse outcomes of secondary traumatic symptoms experienced by secondary school teachers on their compassion fatigue, burnout, sense of satisfaction, and intention to resign from the teaching profession in low SES schools in the United States context. The study was inspired by Ludick and Figley’s Compassion Fatigue and Resilience model and Figley’s work on Compassion Fatigue. A non-experimental design was employed, and data were gathered from a random sample of 131 teache [...]

by Michael Fossel

Received: 20 March 2018;  Published: 28 March 2018;  doi: 10.21926/obm.geriatr.1801004

All of us are intuitively aware, and many of us explicitly aware as well, of the meaning of geriatrics as a specialty. After all, most of us practice geriatrics or we have been intimately involved with this area and we are know the reality of geriatrics. Or do we? Geriatrics is an oddly ill-defined specialty when you look at it more carefully. Some of us practice medicine, some of us practice in the social sciences, and many of us simply do our jobs day-to-day and try to get by. What we share, however, is the heart [...]

by Ferdaouss Qassimi  , Saïd Boujraf  , Adam Khlifi  , Ghizlane Lamgari  , Zineb El Bourachedy  , Chadya Aarab  , Rachid Aalouane  and Amine Bout

Received: 17 January 2023;  Published: 04 August 2023;  doi: 10.21926/obm.neurobiol.2303176

Alexithymia and personality disorders are common in substance use (SUD) patients. This association remains understudied and is considered to hurt the course and management of substance use disorder patients. To determine the prevalence of personality disorders (PD) and alexithymia in addiction care patients. Besides, we targeted investigating a possible link between alexithymia, different personality disorders and clinical aspects of substance use disorder including severity. This cross-sectional study was conducte [...]

by Bin Ni  , Nidhi Sharma  , Ashley Rosko  , Don M. Benson  and Yvonne A. Efebera

Received: 12 April 2021;  Published: 09 July 2021;  doi: 10.21926/obm.transplant.2103148

Prior to the advent of anti-retroviral therapy (ART), autologous stem cell transplant (ASCT) was relatively contraindicated for multiple myeloma (MM) patients with human immunodeficiency virus (HIV) due to issues associated with stem cell harvest and the risk of opportunistic infections. With the widespread use of ART for control of HIV, ASCT is now the preferred treatment for relapsed lymphoma, the leading hematopoietic malignancy associated with HIV/AIDS. Hence, MM patients with HIV controlled by ART may benefit [...]

by Athina Chasapi  , Konstantinos Balampanis  , Anna Tanoglidi  , Eleni Kourea  , George I. Lambrou  , Vaia Lambadiari  , Fotios Kalfarentzos  , Erifili Hatziagelaki  , Maria Melachrinou  and Georgia Sotiropoulou-Bonikou

Received: 28 January 2019;  Published: 22 May 2019;  doi: 10.21926/obm.hg.1902020

(1) Background: A great number of inflammatory mediators and metabolic biomarkers have been shown to contribute to the development and progression of obesity-induced pathologies, including insulin resistance and nonalcoholic fatty liver disease (NAFLD). Many of those mediators are either targets or activators of nuclear factor-κappa B (NF-κB), which is a key transcription factor and plays a pivotal role in the homeostasis and the regulation of inflammatory signaling pathways in the liver. (2) Methods: Our study po [...]

by Annapaola Mariniello  and Silvia Novello

Received: 15 November 2018;  Published: 22 March 2019;  doi: 10.21926/obm.genet.1901069

Immune oncology treatment with immune checkpoint inhibitors (ICIs) is revolutionizing therapeutic approach for advanced non-small cell lung cancer (NSCLC) patients, in terms of longer survival and improved quality of life. To date, the widely used and approved biomarker is programmed death ligand 1 (PD-L1) expression on tumour cells, but it is considered not accurate and it is more likely that many factors, related to both cancer and host, may better predict response to ICI. Among those factors, great attention is [...]

by Jigar Jogia

Received: 17 April 2017;  Published: 09 July 2017;  doi: 10.21926/obm.neurobiol.1702006

There is a need for early diagnosis, monitoring and treatment of Alzheimer’s Disease (AD) and Mild Cognitive Impairment (MCI). Traditional assessments of cognitive decline have been found to lack sensitivity and accuracy in differentiating varying stages of Dementia and cognitive decline as well as being time consuming in their administration. Key components of cognition namely memory and executive function have been identified as most predicative of AD status. Brief cognitive screening tools such as the Montreal C [...]

by Melissa Lopez-Pentecost  , Francine C. Gachupin  , Robin Hazelwood  , Otellie Honanie  , Jessica Quamahongnewa  and Cynthia Thomson

Received: 27 September 2022;  Published: 12 January 2023;  doi: 10.21926/rpn.2301002

American Indians (AI) suffer the highest rates of diabetes in the United States (US); a chronic disease that is increasingly prevalent among AI children and is associated with increased risk of cancer. A summer camp was developed to improve disease risk-reducing behaviors, including diet, among AI youth in Arizona. The aim of this study was to examine the efficacy of a one-week intensive summer health camp conducted from 2016 to 2019 on change in dietary behaviors and compliance for Dietary Guidelines for Americans [...]

by Keita Kiuchi  , Katsumasa Kishi  and Kanto Araki

Received: 23 December 2020;  Published: 17 March 2021;  doi: 10.21926/obm.icm.2101010

This study investigated the physical and psychological impacts of elements related to coronavirus disease (COVID-19) and demographic data in Japan both directly and as mediated by stressors, immediately following the rescinding of the state of emergency declaration accompanying the severe acute respiratory syndrome coronavirus 2 outbreak. An online survey was administered to 1,500 Japanese registered with an online outsourcing service. Data were analyzed with structural equation modeling using Mplus. Relatively lar [...]

by David J. Ross

Received: 27 March 2020;  Published: 31 March 2020;  doi: 10.21926/obm.transplant.2001106

by Mario Lefebvre

Received: 26 September 2022;  Published: 08 December 2022;  doi: 10.21926/aeer.2204049

A filtered Poisson process is proposed as a model for river flows. With the help of real-life data, the model parameters are estimated. Mathematical formulae are derived in order to estimate the various return periods of the river. An application to two rivers shows that the point estimates are very close to the corresponding values computed by hydrologists, based on historical data. Moreover, by modifying the values of the parameters in the model, we can see the potential effects of climate change on the return pe [...]

by Rie Sasaki  , Hiroto Ito  and Masami Okamoto

Received: 01 March 2022;  Published: 14 June 2022;  doi: 10.21926/obm.genet.2202155

In this study, we examined the effect of a combination of surface topographies (fiber alignments) and different stiffness of poly(L-lactic acid) (PLLA) substrates on the direct relationship between anti-cancer drug (CDDP) sensitivity for MDA-MB-231 cells and mesenchymal properties under both normal and hypoxic conditions. In addition, we studied the induction of epithelial–mesenchymal transition (EMT). The CDDP treatment under hypoxia indicated poor adhesion of MDA-MB-231 cells as well as significant repression of [...]

by Hidehiro Kamezaki  , Dai Sakamoto  , Daiki Okamura  , Koji Nakagawa  and Naoya Kato

Received: 10 December 2017;  Published: 14 March 2018;  doi: 10.21926/obm.hg.1801006

(1) Background: Endoscopy has become the primary diagnostic and treatment technique for non-variceal upper gastrointestinal bleeding. Despite advancements in therapeutic methods and instrumentation, endoscopic hemostatic failure occurs in 10% of patients. This study aimed to analyze endoscopic findings in patients with failed hemostasis and to elucidate strategies for endoscopists and gastroenterologists to facilitate improved treatment outcomes. (2) Methods: A total of 128 patients received hemostatic treatment fo [...]

by Vsévolod Mymrin  , Reinaldo H. G. Alarcon  , Marilia A. Guidolin  , Kirill Alekseev  , Rogerio J. Hultmann  , Walderson Klitzke  , Karina Q. Carvalho  , Fernando H. Passig  , Charles W.I. Haminiuk  and Rodrigo E. Catai

Received: 08 December 2022;  Published: 27 February 2023;  doi: 10.21926/cr.2301009

Methanol synthesis catalyst (MSC) waste was applied as the principal component (till 70 wt.%) of sustainable ceramics in composites with bauxite processing waste (RM), and waste foundry sand (FS). The results of the initial components' chemical interaction studies by a complex of methods (XRD, SEM/EDS/mapping, AAS and LAMMA) during heating demonstrated the synthesis of amorphous glasslike new formation, their filling of pores and compaction of the ceramic’s structure. In this case, a strong chemical and mechanical [...]

by Jennifer A. King  , Megan R. Holmes  , Kylie Evans  , Anna E. Bender  and Dakota King-White

Received: 28 February 2023;  Published: 07 September 2023;  doi: 10.21926/obm.icm.2303036

The COVID-19 pandemic exacerbated the long-standing issues of stress and burnout in the education sector, with teachers and education staff facing unprecedented challenges including significant adjustments to teaching methods and balancing the mental health and academic needs of their students. The resulting challenges have contributed to heightened levels of stress and burnout among teachers and education staff. The impact of the pandemic on teachers and education staff has highlighted the need for greater support [...]