Table of Content

Open Access Review

Treating Dementia Early: Limiting Cellular Damage in Brain Tissue

Received: 27 December 2018;  Published: 17 June 2019;  doi: 10.21926/obm.geriatr.1902057

Abstract

Much evidence has been published which indicates that microvascular endothelial dysfunction, due to cerebrovascular risk factors (e.g., atherosclerosis, hypertension, obesity, diabetes, smoking, aging), precedes cognitive decline in Alzheimer's disease and contributes to its pathogenesis. By incorporating appropriate drug(s) into biomimetic (lipid cubic phase) nanocarriers, one obtains a multitasking combination therapeutic which targets certain cell-surface scavenger receptors, and crosses the blood-brain barrier [...]

1723 9854

Open Access Project Report

An Evaluation of a Community-Based Psychoeducation Program for Successful Ageing

Received: 29 October 2018;  Published: 26 April 2019;  doi: 10.21926/obm.geriatr.1902050

Abstract

Background: The increasing numbers and proportion of the ageing population make it essential to develop and evaluate programs to meet the needs of older adults to empower them to age actively, healthily and successfully. Consequently, positive ageing programs have been developed and the need to evaluate their outcomes is essential. This study used mixed methods to evaluate cognitive and behavioural changes and to monitor psychological health and active ageing in participants of a longstanding positive ageing psycho [...]

1723 12012

Open Access Original Research

Empirical Examination of Caregiving Processes and Outcomes among Adult Siblings of Individuals with Intellectual and Developmental Disabilities

Received: 25 February 2019;  Published: 20 May 2019;  doi: 10.21926/obm.geriatr.1902054

Abstract

Background: Most individuals with disabilities in the US live in family settings; in some families, siblings are default long-term support providers. Although researchers have explored the roles of parent caregivers, the roles of sibling caregivers need attention. Methods: In this study, we examined caregiving processes and outcomes among 322 adult sibling support providers (SSPs) with a range of support roles. Adapting a model of caregiving outcomes, we used structural equation modeling to assess relationships amo [...]

1722 10977

Open Access Research Article

Using Health-Related Quality of Life (SF-36v2®) to Predict Falls in Community-Dwelling Older Adults

Received: 14 September 2019;  Published: 25 October 2019;  doi: 10.21926/obm.geriatr.1904082

Abstract

Background: Falls are the leading cause of hospitalization and death among older adults; therefore, the ability to predict fall risk among older adults is critical. Several performance-based outcome measures exist to assess fall risk. Psychological factors are also associated with fall risk yet can be difficult to assess and are often overlooked. In this study, we investigated whether the Short Form 36 Item Health Survey (SF-36v2®), a measure of health-related quality of life (HRQOL), predicted future falls in [...]

1719 11329

Open Access Original Research

Missing Voices and Aging in Prison: Religiosity’s Influence on Positive Aging through Forgiveness

Received: 24 August 2018;  Published: 06 November 2018;  doi: 10.21926/obm.geriatr.1804018

Abstract

Background: This study investigated the influence of positive psychological predictors, religiosity and forgiveness, on subjective and objective successful aging outcomes among incarcerated males. Methods: Male prison inmates (N=261), aged 45 to 82 and incarcerated in eight state-managed correctional facilities, were sampled from the prison census database (Oklahoma Department of Corrections or DOC). Exclusion criteria, per the Oklahoma DOC, were those housed in medical or psychiatric units, currently in solitary c [...]

1719 11851

Open Access Original Research

Exploring the Paradox of Care: Differences in Older Adult and Proxy Ratings of Health and Subjective Well-Being

Received: 27 August 2018;  Published: 27 February 2019;  doi: 10.21926/obm.geriatr.1901037

Abstract

Background: The purpose of this study was to examine discrepancies in self-proxy agreement of biopsychosocial factors and the influence of objective well-being and psychosocial resources self and proxy appraisals of subjective well-being in older adults. Methods: Seventy-two older adult-proxy dyads rated the biopsychosocial health of non-cognitively impaired older adults. Results: Proxies underestimated functional ability, psychosocial factors, and overrated negative health outcomes compared to older adults. Older [...]

1717 11101

Open Access Original Research

Simultaneous Localization and Mapping (SLAM) for Route Reversal Learning

Received: 25 May 2018;  Published: 09 August 2018;  doi: 10.21926/obm.geriatr.1803007

Abstract

Background: In this paper, we describe the design of a virtual environment (VE) using Simultaneous Localization and Mapping (SLAM) to scan and replicate a real environment (RE) in a virtual domain. Compared to using a CAD software, SLAM allows for the replication of an RE quite easily and quickly. Methods: To test the user’s performance in a SLAM-based VE, we developed an immersive virtual reality setup using a specialized wheelchair (VRNChair) and a head mounted display (Oculus Rift DK2), and employed a knowledge [...]

1706 11876

Open Access Original Research

Views of Conventional Medicine and Integrative Medicine among Informal Dementia Caregivers and Healthcare Professionals in NW England

Received: 06 September 2019;  Published: 21 January 2020;  doi: 10.21926/obm.geriatr.2001102

Abstract

The urgent need for innovative approaches to dementia treatment that are acceptable, effective and affordable underlies this research. Growing evidence supports ‘integrative medicine’ as a potential treatment approach aligned with and including conventional medicine. However, success will depend on addressing barriers, recognising needs of diverse communities and involving people in co-creating desired interventions. The three aims of this study were to, 1) describe conventional allopathic medicine and integrative [...]

1698 13221

Open Access Original Research

Sexual Orientation and Risk for Elder Abuse: Findings from the Canadian Longitudinal Study on Aging

Received: 03 October 2023;  Published: 04 December 2023;  doi: 10.21926/obm.geriatr.2304260

Abstract

This study addresses knowledge gaps concerning prevalence and risk factors for elder abuse among sexual minority (SM) compared to heterosexual Canadians aged 65+. Data derive from the Canadian Longitudinal Study on Aging, a national cohort study. Outcome variables include self-reports of psychological, physical, or financial abuse in the 12 months before interview and overall. Main explanatory variables are sexual orientation and gender identity; covariates include other socio-demographic characteristics, general a [...]

1693 23266

Open Access Review

Polymyalgia Rheumatica, an Age-Related Rheumatic Disease

Received: 07 May 2022;  Published: 27 July 2022;  doi: 10.21926/obm.geriatr.2203202

Abstract

Polymyalgia rheumatica (PMR) is an age-related chronic inflammatory disease with rheumatic features at the fore. In addition to the high-grade systemic inflammation, it is characterized by typical "polymyalgic" musculoskeletal symptoms, including diffuse and severe pain and prolonged morning stiffness of the shoulder girdle, pelvic girdle, and neck. PMR is a member of the so-called giant cell arteritis complex; however, in spite of the marked systemic inflammation in PMR, the local vasculitis process aborts. The pa [...]

1690 19760

Open Access Review

A is for Autophagy and Alzheimer's

Received: 01 August 2018;  Published: 25 November 2018;  doi: 10.21926/obm.geriatr.1804020

Abstract

Improved understanding of the underlying cellular dysfunction and resultant neuropathology of sporadic Alzheimer’s disease (AD) is needed to stem the anticipated public health crisis due to this increasingly common neurodegenerative disease. The four main risk factors for sporadic AD are age, female gender, genetic carriage of the APOE4 allele and type two diabetes mellitus (T2DM). Each of these four risk factors is associated with impaired and/or dysfunctional autophagy suggesting that perturbation of autophagy is [...]

1689 10395

Open Access Technical Note

Improving the HealthCare of People with Dementia beyond the Diagnosis: The “Carlo Poma Dementia Care Pathway” Study Protocol

Received: 31 October 2018;  Published: 27 February 2019;  doi: 10.21926/obm.geriatr.1901036

Abstract

The WHO global action plan on the public health response to dementia 2017-2025 stressed the need to have a comprehensive approach with deep interconnections and cross-cutting elements through several action areas. As the elderly population grows worldwide, the number of patients with dementia increases rapidly because age is an important risk factor for developing late-onset dementia. Currently, dementia syndrome represents a true emergency. Once a diagnosis of dementia was made, informal caregivers, patients and t [...]

1686 14015

Open Access Research Article

Translation and Validation of “Brief Bedside Dysphagia Screening Test” in a Greek Sample of Neurological Patients

Received: 09 October 2020;  Published: 02 April 2021;  doi: 10.21926/obm.geriatr.2102165

Abstract

Dysphagia may become a threatening condition if not diagnosed and treated at an early stage. Healthcare professionals require simple, rapid, and reliable tools for the immediate evaluation of dysphagia in their daily clinical practice. The aim of the present study was the translation and validation of the “Brief Bedside Dysphagia Screening Test-Revised (BBDST-R)” tool in the Greek language in a sample of patients with neurological disorders. The present study was designed as a cross-sectional study cond [...]

1684 9475

Open Access Review

Physical Activity’s Impact on Quality of Life in Older Adults with Dementia: A Systematic Review

Received: 04 June 2020;  Published: 23 September 2020;  doi: 10.21926/obm.geriatr.2003133

Abstract

Individuals with dementia frequently report poor quality of life (QOL), which declines as their disease progresses. Some evidence suggests that physical activity may help maintain cognitive function in older age, but it is unclear whether physical activity affects quality of life in older adults with dementia. The purpose of this review paper is to explore whether and how physical activity impacts QOL in patients with diagnosed dementia in different residential settings. To conduct this systematic review, the follo [...]

1678 13228

Open Access Research Article

Surgical Treatment of Zenker’s Diverticulum in Older Patients

Received: 26 October 2020;  Published: 18 August 2021;  doi: 10.21926/obm.geriatr.2103179

Abstract

Zenker’s diverticulum is a cause of benign dysphagia. The main symptoms include dysphagia and regurgitation and require diagnostics to exclude neoplastic disease. Surgical treatment is recommended for symptomatic patients. The methods of treatment include endoscopic and open transcervical techniques. Thirty-eight patients treated using the open technique between 2000 and 2020 were analyzed. Patients were qualified for the procedure after a complete diagnosis that excluded the neoplastic process. All patients were a [...]

1678 13877

Open Access Original Research

Positive Aging a Two-Way Street: Healthy Lifestyle and Attitudes of Others

Received: 07 August 2018;  Published: 18 October 2018;  doi: 10.21926/obm.geriatr.1804015

Abstract

Background: Previous research has indicated the attitudes that others have toward older adults play an important role in their well-being. The current study contributes to the literature because it evaluates attitudes toward older adults. Methods: The participants included Caucasian and Indigenous people residing in Northern Ontario. All participants were asked to complete a demographics questionnaire and the Kogan’s Attitudes Toward Old People Scale (KAOP). Results: Results indicated that Indigenous participants h [...]

1673 9784

Open Access Research Article

Stenting of the esophagus in the course of the malignant dysphagia in elderly patients

Received: 26 October 2020;  Published: 07 June 2021;  doi: 10.21926/obm.geriatr.2102171

Abstract

Esophageal cancer is a disease with difficult clinical management, and palliative therapy is the only predominant treatment. This retrospective study analyses the results of clinical management of elderly patients (>75 years of age) who were treated with esophageal stenting for malignant dysphagia due to primary esophageal cancer, including squamous cell carcinoma (SCC), esophageal adenocarcinoma (EAC), as well as secondary esophageal malignant strictures due to non-small cell lung cancer (NSCLC). Patients with [...]

1670 11793

Open Access Research Article

Post-Mortem Comparison of the Incidence and the Distribution of Cerebrovascular Lesions Using Additional 7.0-Tesla Magnetic Resonance Imaging in Cognitive Normal Young, Middle-Aged, and Elderly Persons

Received: 06 April 2020;  Published: 04 June 2020;  doi: 10.21926/obm.geriatr.2002122

Abstract

Regional brain atrophy and an escalation in vascular risk are associated to increasing age in normal cognitive healthy persons. The present post-mortem study compares the incidence of cerebrovascular lesions between young-aged, middle-aged, and elderly cognitive normal persons with additional 7.0-tesla MRI). The patients consisted of 10 young adults, 20 middle-aged adults, and 14 elderly ones. In addition to the macroscopic visible cerebrovascular lesions, a whole coronal section of a cerebral hemisphere was taken [...]

1666 9577

Open Access Review

Management of Older People With Diabetes - A Focus On Mental Functions

Received: 05 March 2020;  Published: 01 April 2020;  doi: 10.21926/obm.geriatr.2002113

Abstract

The prevalence of diabetes in older people is increasing. Diabetes in old age is associated with increased risk of mental dysfunction. Cognitive dysfunction and mood disorders such as depression, anxiety and diabetes-related distress tend to coexist in older people with diabetes and appear to have bidirectional relationship acting as a risk factor and, at the same time, as a consequence of diabetes. To break the vicious circle of this complex reciprocal relationship between diabetes and mental dysfunction, early id [...]

1665 11274

Open Access Editorial

Fragility Fractures in the Elderly Osteoporotic Patient and the Efficacy of Fracture Liaison Service Programs

Received: 07 November 2019;  Published: 13 November 2019;  doi: 10.21926/obm.geriatr.1904085

Abstract

None.

1662 9204

Open Access Review

Parting with the Concept of Alzheimer’s Disease in Senium

Received: 30 March 2019;  Published: 08 July 2019;  doi: 10.21926/obm.geriatr.1903060

Abstract

The understanding of mental deterioration associated with old age has undergone several changes over the past two centuries, and has spurred major scientific debates. In the 19th century, this disorder was still considered an inevitable part of aging. The beginning of the 20th century offered a histological explanation for presenile dementia, and Alois Alzheimer was credited as the discoverer of a new disease that bears his name to date. In the last quarter of the 20th century, findings of Alois Alzheimer were appl [...]

1660 10711

Open Access Review

Biomaterial to Improve Drug Delivery in Alzheimer's Disease: Linking Major Pathogenic Pathways

Received: 26 December 2019;  Published: 28 February 2020;  doi: 10.21926/obm.geriatr.2001110

Abstract

Aging, hypertension, diabetes, obesity, atherosclerosis, traumatic brain injury, and other factors can all synergistically promote diverse pathological mechanisms. These risk factors trigger widespread inflammation and oxidative stress, both of which can lead to blood-brain barrier (BBB) disruption. These pathological cascades lead to neuronal Ca2+ increase, neurodegeneration, gradual cognitive/memory decline, and eventually Alzheimer's disease. In particular, more recent research indicates that chronic inflamm [...]

1660 9972

Open Access Editorial

Gene Therapy Comes of Age

Received: 12 December 2017;  Published: 24 December 2017;  doi: 10.21926/obm.geriatr.1704003

1658 9041

Open Access Original Research

Molecular Basis of Allogeneic Pluripotent Stem Cell Treatment of a Patient with Sporadic ALS

Received: 21 August 2020;  Published: 29 March 2021;  doi: 10.21926/obm.geriatr.2101164

Abstract

There are no curative strategies for ALS, and as a result the alternative therapies are gaining ground, in particular the stem cell-based therapies which hold a promising future. Here we describe an ALS patient, who by choice, received allogeneic human cord-blood derived multipotent stem cells (MSC) intravenously and intrathecally. This is the first snapshot of pre-and post-stem cell transplantation in an ALS patient through transcriptomic, epigenomic, and proteomic follow-up elucidating the effect of stem cells in [...]

1656 11523

Open Access Original Research

Adaptation to Residential Care: Voices from New Zealand

Received: 25 May 2023;  Published: 01 December 2023;  doi: 10.21926/obm.geriatr.2304259

Abstract

This article explores the adaptation process of older adults in residential care facilities in New Zealand. Through a phenomenological approach, this study provides clarity on how older adults adjust in residential care despite losses and challenges. Qualitative data on 24 older adults, 6 residential care facilities, and 10 staff were collected. Utilising qualitative software the following were identified: loss, support, acceptance and meaningful support. Initially, the unfamiliar environment and faces, structured [...]

1652 12174

Open Access Opinion

Yoga: A Potential Adjunct Therapy to Current Rehabilitation Pathways in Cardiac Conditions and Stroke

Received: 06 August 2020;  Published: 28 January 2021;  doi: 10.21926/obm.geriatr.2101155

Abstract

Yoga is a form of movement-based mindfulness practice that enhances the mind-body connection to benefit overall health and well-being. Although the practices of yoga are ancient traditions in the Buddhist and Hindu philosophies, scientific research regarding the impacts of yoga among people with poor cardiovascular and cerebrovascular health has only recently been undertaken. In this article, we highlight the current evidence on the potential impact of yoga on physical and psychological well-being for older adults [...]

1638 10117

Open Access Perspective

Target Tau, not Amyloid, to Prevent and Treat Alzheimer’s Disease

Received: 27 November 2019;  Published: 04 February 2020;  doi: 10.21926/obm.geriatr.2001103

Abstract

In this article I wish to put the case for a change of emphasis in the approach to finding a prevention/treatment for Alzheimer’s disease from a focus on beta amyloid to one on tau. In particular, I make the case for aiming to prevent the spread of abnormal tau from the medial temporal lobe to widespread areas of association cortex that are anatomically linked to this critical region. I pose an analogy with cardiovascular disease in which the initiating pathology, lipid streaks, are left untreated until they are so [...]

1636 9556

Open Access Hypothesis

Sporadic Alzheimer Disease and That Developing in Down’s Syndrome: The Immune System Attacking Self Rather Than Suppressing Infectious Disease Invaders, Toll Like Receptors Triggering Excessive Cytosolic Calcium, Excess Calcineurin Activation, Overexpression of Regulator of Calcineurin1, Runaway Beta-Amyloid Production, Synaptic Loss, Destructive Inflammation and Dementia

Received: 29 August 2018;  Published: 26 February 2019;  doi: 10.21926/obm.geriatr.1901035

Abstract

Alzheimer Disease may result from excessive stimulation of the innate immune system from development of underlying opportunistic infections and impaired age related self-recognition as non-self, due to immunodeficiency and immunosenescence, resulting in excessive inflammation and runaway Beta-amyloid production (a component of the innate immune system) causing cytosolic calcium overload. Excessive cytosolic calcium may cause over activation of calcineurin and inactivation of cis-trans prolyl isomerase (Pin1), with [...]

1636 9789

Open Access Original Research

Using Mixed Methods to Explore Older Residents' Physical Activity and Experiences of Community Active Aging Friendliness

Received: 29 October 2018;  Published: 06 January 2020;  doi: 10.21926/obm.geriatr.2001098

Abstract

Physical inactivity is the fourth leading risk factor for global mortality and as such, it is critical that physical activity guidelines for health consider equitable access to physical activity opportunities for all, including those aged 65 years and older. The purpose of this study was to examine the intersections of attributes of older people (e.g. income, gender, age, health, physical activity) and attributes of the places they live (e.g. rurality, public transit, sidewalks, parks, community centre) to explain [...]

1634 9973

Open Access Review

AI-Powered Solutions to Support Informal Caregivers in Their Decision-Making: A Systematic Review of the Literature 1

Received: 15 October 2023;  Published: 15 December 2023;  doi: 10.21926/obm.geriatr.2304262

Abstract

Due to aging demographics, prolonged life expectancy, and chronic diseases, European societies' increasing need for care services has led to a shift towards informal care supplied by family members, friends, or neighbors. However, the progressive decrease in the caregiver-to-patient ratio will result in a significant augmentation in incorporating intelligent aid within general care. This study aimed to build upon the authors' previous systematic literature review on technologies for informal caregivers. Specificall [...]

1633 12196

Open Access Case Report

Dysphagia Aortica: A Case Report and Review of Treatment Options

Received: 29 October 2020;  Published: 05 February 2021;  doi: 10.21926/obm.geriatr.2101157

Abstract

A 64-year-old, cachectic man with body mass index (BMI)

1633 13594

Open Access Research Article

Factors Determining Subjective Health Perception Among Middle-and Upper-Middle Aged Individuals

Received: 15 October 2021;  Published: 24 February 2022;  doi: 10.21926/obm.geriatr.2201190

Abstract

In the present study, we identified the factors of cognitive and physical performances predicting self-rated health perception (SRH) using an SRH questionnaire in 660 (298 men and 362 women) upper-middle-aged community dwellers. In addition, neuropsychological test battery and physical ability tests were applied. A multiple regression analysis was conducted using the forced entry method; digit cancellation test (D-CAT1), logical memory test, verbal fluency test, back strength, timed-up and-go (TUG), balancing test, [...]

1624 9330

Open Access Comment

hTERT Promoter Regulation by Differentiation Mechanisms vs Telomerase Activity in Somatic, Embryonic, and Cancerous Cells

Received: 02 February 2019;  Published: 04 April 2019;  doi: 10.21926/obm.geriatr.1902045

Abstract

Telomere shortening in the somatic cells is one of the most well-documented factors of cellular ageing. Telomeres are composed of tandem hexanucleotide repeats that protect cells from unwanted recombination mechanisms, secure the ends of chromosomes and their stability, and are responsible for limited division capacity. Telomerase is an enzymatic ribonucleoprotein complex, present in embryonic cells, adult stem cells, and germinal progenitors, whose function is to extend the telomeres length by adding the lost tand [...]

1622 12784

Open Access Original Research

Cognitive and Physical Indicators of Gait Speed in the Community-dwelling Older Adult

Received: 16 November 2021;  Published: 15 February 2022;  doi: 10.21926/obm.geriatr.2201188

Abstract

Gait speed has been correlated to quality of life and has been called the sixth vital sign. The purpose of this study was to understand the factors that comprise fast and comfortable gait speed. 90 older adults provided demographic, cognitive, and functional performance data. Hierarchical linear regression models revealed predictors for comfortable gait speed to be lower-extremity strength ( B = 1.13, β = 0.233, P< .05), comorbid health ( B = −2.95, β = −0.22, P < 0.05), and gender( B = [...]

1614 16689

Open Access Communication

Making Sense of Senselessness: Contemporary Literary Commentaries on Dementia

Received: 20 December 2018;  Published: 17 June 2019;  doi: 10.21926/obm.geriatr.1902056

Abstract

Alzheimer’s Disease is increasingly seen as the major health problem in developed countries supplanting cancer and heart disease. The terror with which we respond to dementia, is grounded in a view of dementia as a monstrous descent, ambushing our healthy ageing through an incursion of pathology. The pervasiveness of this view can mean that other perspectives and even the views of those most touched by the challenges of dementia remain unheard. Part of the cultural conversation around dementia is informed by [...]

1611 8443

Open Access Original Research

Wisdom of the Elders: Narratives Enhancing Trainees’ Attitudes Towards Aging

Received: 25 April 2019;  Published: 26 August 2019;  doi: 10.21926/obm.geriatr.1903072

Abstract

Background: Narratives encompass written reflection experiences and hold the potential to display valuable insights into trainees’ thinking. We analyzed narratives from graduate students trained in aging themes, who then interviewed older hospitalized adults (senior partners) about their life experiences. Methods: Three Discovery & Learning Fellows trained on open-ended interviewing, empathy, and aging themes performed semi-structured interviews. Senior partners were hospitalized older veterans. After the [...]

1599 9692

Open Access Review

Deep Brain Stimulation – Therapeutic Possibilities in Alzheimer's Disease

Received: 02 December 2020;  Published: 30 April 2021;  doi: 10.21926/obm.geriatr.2102170

Abstract

Alzheimer’s Disease (AD) is the leading cause of dementia worldwide, and represents a significant cause of cognitive decline, disability, and mortality. Ongoing clinical trials continue to investigate β-amyloid targeted therapy with unclear benefit, and we are currently limited to symptomatic treatment. Therefore, there is a salient need for the development of novel, potentially disease-modifying therapeutic strategies such as deep brain stimulation. This manuscript reviews Deep Brain Stimulation in Alzheimer’s Dis [...]

1596 10329

Open Access Original Research

Atrial Fibrillation, Anticoagulation, and Major Bleeding Episodes in Geriatric Patients at the Risk of Falling

Received: 22 May 2019;  Published: 26 August 2019;  doi: 10.21926/obm.geriatr.1903071

Abstract

Background: Geriatric patients are at risk of atrial fibrillation (AF) and stroke, and the risk of oral anticoagulation (OAC) related bleeding is also presumed to be higher. Detailed knowledge about the prevalence of AF and bleeding pattern in this population is scarce. This study sought to assess the prevalence of AF, use of OAC, and the rate of major bleeding in geriatric patients who are prone to frequent falls. We expect to find a higher prevalence of AF among geriatric patients compared to elderly people of co [...]

1596 10291

Open Access Editorial

OBM Geriatrics—An International Open Access Journal for 21st Century Geriatrics Medicine

Received: 11 December 2016;  Published: 06 January 2017;  doi: 10.21926/obm.geriatr.1701001

Abstract

Geriatrics, and much of clinical medicine, is on the verge of a profound transformational shift. Until now, there has been a sharp conceptual divide between diseases which can be readily and effectively treated, and diseases which we have thought to be beyond clinical intervention. In the first disease category, are many of the most common infections that respond to antibiotics and immunizations. We have made dramatic changes in the demographics and the mortality of many such treatable diseases. At the other extrem [...]

1596 16654

Open Access Short Review

Alzheimer's Disease: Parsing the Pathways Leading to the Disease Based on the Spirochete/Biofilm Hypothesis

Received: 30 December 2019;  Published: 19 February 2020;  doi: 10.21926/obm.geriatr.2001107

Abstract

A pathway which highlighted spirochetes (Borrelia burgdorferi and dental treponemes) that made biofilms which led to Alzheimer’s disease has recently been promulgated. All the Alzheimer’s disease, on which this pathway was based, had been specifically confirmed both clinically and pathologically. This current work will show putative and plausible individual pathways that were studied. First and foremost, intracellular spirochetes make biofilms and concurrently make beta amyloid; this has been shown in v [...]

1592 9406

Open Access Review

Heart Failure in Elderly People: From Pathophysiology to Diagnosis and Management

Received: 05 March 2023;  Published: 19 September 2023;  doi: 10.21926/obm.geriatr.2303250

Abstract

As the older population increases, there is an increase in age-related chronic diseases, especially heart failure. It affects 25% of over 75-year-old outpatients and represents the leading cause of hospitalization and death in older people. This review aimed to point out the main characteristics concerning heart failure in older people, taking into account clinical symptoms, diagnosis, and treatment. An extensive search on heart failure was made on PubMed and Google, using the keywords older people, heart failure, [...]

1591 14071

Open Access Editorial

What is Geriatrics?

Received: 20 March 2018;  Published: 28 March 2018;  doi: 10.21926/obm.geriatr.1801004

Abstract

All of us are intuitively aware, and many of us explicitly aware as well, of the meaning of geriatrics as a specialty. After all, most of us practice geriatrics or we have been intimately involved with this area and we are know the reality of geriatrics. Or do we? Geriatrics is an oddly ill-defined specialty when you look at it more carefully. Some of us practice medicine, some of us practice in the social sciences, and many of us simply do our jobs day-to-day and try to get by. What we share, however, is the heart [...]

1591 9285

Open Access Research Article

Older People and the Construction of Virtual Identities in the Digital Culture

Received: 06 February 2023;  Published: 10 May 2023;  doi: 10.21926/obm.geriatr.2302235

Abstract

This research study addresses certain theoretical issues surrounding the relationship between digital technologies, the aging population, and identity. At the same time, it offers a conceptual proposal of indicators of the social inclusion of older people in the digital culture of society as a potential starting point for further empirical research. The progressive trend of a growing proportion of older people is a demographic reality in many economically and technologically advanced societies. This demographic agi [...]

1585 10037

Open Access Editorial

Driving Skills in Older Adults

Received: 11 August 2020;  Published: 19 August 2020;  doi: 10.21926/obm.geriatr.2003130

1578 7813

Open Access Concept Paper

Using Elder Abuse Case Studies to Develop LGBTQ+ Cultural Competency

Received: 16 July 2023;  Published: 15 January 2024;  doi: 10.21926/obm.geriatr.2401266

Abstract

Lesbian, gay, bisexual, transgender, and queer (LGBTQ+) elders are vulnerable to both the “usual” types of elder abuse (physical, sexual, emotional, and financial abuse, along with neglect), and with abuse that is specific to the context and history of LGBTQ+ elders. Training for adult protective services, long-term care ombudsmen, and other professionals who work with abused elders therefore should include information and skill-building in responding to this population. Research into effective training about LGBTQ [...]

1571 8210

Open Access Research Article

Comparison of Post-mortem 7.0-Tesla Magnetic Resonance Imaging of the Brains of Alzheimer Patients with and without Cerebral Amyloid Angiopathy

Received: 24 September 2020;  Published: 10 December 2020;  doi: 10.21926/obm.geriatr.2004142

Abstract

The influence of cerebral amyloid angiopathy (CAA) in Alzheimer’s disease (AD) remains unexplored. The present post-mortem study investigated possible differences in the degree of hippocampal atrophy (HA) between AD patients with and without CAA using 7.0-tesla magnetic resonance imaging (MRI). Also, the incidence of the hippocampal cortical micro-infarcts (HCoMIs) and hippocampal cortical micro-bleeds (HCoMBs) is compared to those in the neocortex. The examined post-mortem brains included 30 AD-CAA cases and 20 AD [...]

1569 7911

Open Access Review

Trajectories and Status of Transgender Elderly Across the World and in Spain: A Narrative Review

Received: 06 November 2023;  Published: 27 February 2024;  doi: 10.21926/obm.geriatr.2401271

Abstract

Older trans people have been largely unaddressed both in the context of the LGBTIQ+ community and in studies on geriatrics and aging. This literature review compiles up-to-date information on transgender elders, providing a summary of the Spanish historical context in which trans people have been raised, and analyzes the areas in which to center possible courses of action and research on a global scale. The themes tackled are the presence of victimization and violence; the effects of medical transition, taking into [...]

1569 11389

Open Access Original Research

Differential Effects of Social Network on Health in Later Life and the Moderating Role of Depression

Received: 23 March 2019;  Published: 12 August 2019;  doi: 10.21926/obm.geriatr.1903067

Abstract

Background: Differential effects of the characteristics of social network on limitations with activities (LWA) and the quality of life (QOL) among older adults, and the moderating role of depression were studied. Methods: The data obtained from two consecutive waves of the Survey of Health, Aging, and Retirement in Europe (SHARE) was examined. Results: Emotional closeness, satisfaction with the social network, and contact frequency were able to predict the QOL and not LWA. Moreover, depression was observed to moder [...]

1568 10944

Open Access Editorial

Acknowlegement to Reviewers of OBM Geriatrics in 2020

Received: 04 January 2021;  Published: 06 January 2021;  doi: 10.21926/obm.geriatr.2101149

Abstract

The editors of OBM Geriatrics would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2020. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers receive a voucher entitling them to a discount on their next LIDSEN publication and can download a certificate of recognition [...]

1562 6869

Open Access Original Research

Role of Activity Professionals in Applying APIE Model to Enhance Residents’ Activity and Engagement in Long-Term Care Settings

Received: 23 August 2022;  Published: 25 June 2023;  doi: 10.21926/obm.geriatr.2302239

Abstract

Residents’ activity is a strong contributor to the quality of life in long-term care facilities. Hence, activity professionals have an essential role to play in enhancing residents’ activity engagement. Professional practice model for activity professionals includes Assessment, Planning, Implementation, and Evaluation (APIE model). Although activity professionals have made advances in demonstrating their value, few studies have focused on the APIE model for activity professionals in long-term care facilities. A sur [...]

1561 11848

TOP