by Vincenza Rita Lo Vasco

Received: 27 January 2023;  Published: 05 May 2023;  doi: 10.21926/obm.geriatr.2302234

Illnesses following the degeneration of the nervous system can occur due to aging or genetic mutations and represent a clinical concern. In neurodegenerative diseases, loss of neuronal structure and functions mainly causes cognitive impairment, representing an increasing social burden. In neurodegenerative diseases, the progressive loss of vulnerable populations of neurons in specific regions of the central nervous system was traced to different pathological events, such as misfolded proteins’ accumulation, abnorma [...]

by Kenneth J. McLeod

Received: 24 April 2023;  Published: 18 September 2023;  doi: 10.21926/obm.geriatr.2303249

Chronically low blood pressure in older adults is associated with significantly increased long-term risks of dementia and all-cause mortality risk. Yet low blood pressure is generally not treated until an individual begins to experience the acute symptoms arising from very low cerebral perfusion. However, these acute symptoms, such as dizziness, balance difficulty, syncope, increased fall occurrence, vision impairment, and nausea, begin to occur only at very low blood pressure levels, such that mean arterial pressu [...]

by Mélanie Couture  , Julien Gauthier-Mongeon  , Pearce Simamonika  , Rosalie Bernard  , Kevin St-Martin  , Rosalie Lacasse  and Sarita Israel

Received: 18 December 2023;  Published: 17 July 2024;  doi: 10.21926/obm.geriatr.2403282

Research indicates that adults in the context of gender and sexual diversity (GSD) experienced more violence and discrimination than the rest of the population. GSD refers to all the diversities of sexual characteristics, sexual orientations and gender identity of a person or a group. To encourage the use of evidence-based interventions in health and social services, it is important to extrapolate from the scientific literature how mistreatment situations are managed in this context. A scoping review was conducted [...]

by Helena Andrade Figueira  , Olivia Andrade Figueira  , Alan Andrade Figueira  , Carlos Roberto Lyra da Silva  , Joana Andrade Figueira  and Estelio Henrique Martin Dantas

Received: 14 October 2022;  Published: 29 December 2022;  doi: 10.21926/obm.geriatr.2204219

The World Health Organization attracted more attention to the positive effects of physical activity (PA) and the adverse effects of stress on the health of older people and, therefore, attracted a more significant number of practitioners. To verify the impact of PA on stress in older people. Observational and analytical research, composed of 690 older people of both genders residing in Brazil, present in street races (as participants or observers), who volunteered to respond to the research protocol consisting of s [...]

by Giuseppe Cocco

Received: 20 March 2020;  Published: 01 April 2020;  doi: 10.21926/obm.geriatr.2002112

by Philip Brown  , Dana Buelsing Sowards  , Mary Pittman  , Gisele Leger  and Susan DeSipio Manns

Received: 27 February 2023;  Published: 25 May 2023;  doi: 10.21926/obm.geriatr.2302237

In August 2022, the Centers for Medicare and Medicaid Services (CMS) adopted its first-ever nutrition electronic clinical quality measure (eCQM), known as the Global Malnutrition Composite Score (GMCS) as part of the Inpatient Hospital Quality Reporting (IQR) Program. Starting in January 2024, hospitals can self-select to include the GMCS as one of three optional eCQMs for reporting. This article focuses on the importance of addressing malnutrition to improve the overall health of the aging population, reduce preve [...]

by Gopi Battineni  , Mohammad Amran Hossain  , Nalini Chintalapudi  , Giulio Nittari  , Ciro Ruocco  , Enea Traini  and Francesco Amenta

Received: 29 June 2022;  Published: 03 January 2023;  doi: 10.21926/obm.geriatr.2301220

The increasing incidence of adult-onset dementia disorders and primarily Alzheimer’s disease (AD) among the aging population around the world is increasing the social and economic burden on society and healthcare systems. This paper presents three neural networking algorithms: MobileNet, Artificial Neural Networks (ANN), and DenseNet for AD classification based on MRI imaging data. The results of each model were compared in terms of performance metrics such as accuracy, true positive rate, and receiver operating cu [...]

by Ayan Mishra  , Barsha Panda  and Debosree Ghosh

Received: 10 May 2023;  Published: 26 October 2023;  doi: 10.21926/obm.geriatr.2304255

Non Alcoholic Fatty Liver Disease (NAFDL) is a condition in which an individual suffers from an accumulation of fat in the liver. This is a disease condition with a multifactorial etiology. Some potent causes of such conditions are altered thyroid condition, abnormal metabolism in the body due to aging or menopause, or any other hormonal imbalance. Most of these causes are regulated by genetics, lifestyle, and environmental factors. Menopause comes with tremendous hormonal turmoil in the human body and brings vario [...]

by Julia Henderson

Received: 05 November 2019;  Published: 17 January 2020;  doi: 10.21926/obm.geriatr.2001101

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by Yogendra Keche  , Preetam Wasneek  , Keshao Nagpure  , Nitin Gaikwad  , Suryaprakash Dhaneria  , Sabah Siddiqui  and Apoorva Joshi

Received: 22 August 2022;  Published: 11 December 2022;  doi: 10.21926/obm.geriatr.2204216

The COVID-19 pandemic had imposed a city-level quarantine, local lockdown, and border closures for patient-level isolation to control virus spread. There is a lack of studies on the health-related quality of life (HRQoL) in the elderly in countries like India during COVID-19. After obtaining written informed consent from the elderly patients, data was recorded in the case record form-cum-questionnaire. The quality of life was assessed with the help of Centers for disease control and prevention (CDC) HRQoL-14 measur [...]

by Giuseppe Cocco  , Hans Peter Hofmann  and Stefano Pandolfi

Received: 27 December 2023;  Published: 11 March 2024;  doi: 10.21926/obm.geriatr.2401273

Heart failure is one of the major health threats in Western societies, and its prevalence is steadily increasing. Many data show the important impact of sex (biological) and gender (sociocultural) differences on most aspects (diagnosis, etiology, treatments, and outcomes) of heart failure. For example, compared to men, women with heart failure are older, have more co-morbidities, and develop different phenotypes of heart failure. Postpartum cardiopathy is unique in women. The iatrogenic effects of cancer therapies [...]

by OBM Geriatrics Editorial Office

Received: 06 January 2022;  Published: 06 January 2022;  doi: 10.21926/obm.geriatr.2201186

The editors of OBM Geriatrics would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2021. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers receive a voucher entitling them to a discount on their next LIDSEN publication and can download a certificate of recognition [...]

by Susan E. Reid  , Bessam Abdulrazak  and Tianqi Xiao

Received: 08 August 2022;  Published: 17 October 2022;  doi: 10.21926/obm.geriatr.2204209

Despite the increase in use and interest in mobile devices by older adults, to date, there is still limited research carried out to better understand older adults’ usage and needs as they relate to such devices. As such, this research examined the use of two types of mobile devices, smartphones, and tablets, by older adults (i.e., age 65+), as well as the use of a new interface, developed for research purposes, called “PhonAge”. This study was exploratory, and utilizes frequency data and tables, in order to get a s [...]

by Shashya Wijesinghe  and Elizabeta B. Mukaetova-Ladinska

Received: 03 March 2024;  Published: 10 May 2024;  doi: 10.21926/obm.geriatr.2402279

In the UK, 25,000 people from ethnic minority background live with dementia. Although dementia associated risk factors are common amongst South Asians, they tend to present at services later and when in crisis. This review explores UK South Asian communities perception of dementia to understand factors impacting their decision to seek help. Search terms assisted by the PICO strategy were inputted into five databases and ten qualitative papers identified. Meta-ethnography methodological framework was implemented for [...]

by Brittany Montgomery  , Calvin Mammen  and Matt Golden

Received: 18 October 2024;  Published: 09 May 2025;  doi: 10.21926/obm.geriatr.2502311

Assistive technology (AT) interventions have shown promising results in supporting cognitive, social, and physical activities in persons living with dementia (PLWD) and their caregivers. Despite strong evidence of the effectiveness of AT, PLWD and their caregivers can disengage with the technology after it is used for a time – i.e., the “stickiness challenge”. Diminished use of AT reduces the opportunity for it to have optimal impact. We asked whether the opportunity to engage in cognitive games may enhance continu [...]

by Gloria Gutman  , Mojgan Karbakhsh  and Heather Stewart

Received: 20 December 2023;  Published: 16 April 2024;  doi: 10.21926/obm.geriatr.2402278

Lesbian, gay, and bisexual (LGB) older adults may be more vulnerable to elder abuse (EA) due to prior marginalization and trauma, lifelong discrimination, and health disparities. While characteristics of both victims and perpetrators can modify the risk for EA, few studies have focused on perpetrators. This study examined the number and type of perpetrator-victim relationships and perpetrator profiles for EA experienced in the prior year, by abuse type and sexual orientation and gender identity of the abused. Data [...]

by Clément Dumont  , Madeleine Lefèvre  , Quiterie Aussedat  , Pierre-Louis Régnier  , Alexandra Masson-Lecomte  , Evanguelos Xylinas  , Hélène Gauthier  , Virginie Fossey-Diaz  , Amélie Arégui  and Stéphane Culine

Received: 23 July 2021;  Published: 08 November 2021;  doi: 10.21926/obm.geriatr.2104183

Cisplatin-based neoadjuvant chemotherapy (C-NAC) has been the standard of care in localized muscle-invasive bladder cancer (MIBC). However, the feasibility and benefit of C-NAC in elderly patients remain uncertain since this population has always been underrepresented in pivotal trials and is often barred from chemotherapy in routine practice because of their perceived frailty. Therefore, in order to evaluate the effectiveness of C-NAC in elderly patients with MIBS, we retrospectively reviewed the medical files of [...]

by Mauro Turrin  , Lucia Fornasiero  and Antonio Navarro

Received: 08 January 2023;  Published: 27 June 2023;  doi: 10.21926/obm.geriatr.2302240

We describe the clinical case of a 74-year-old male patient who received the second Comirnaty/Pfizer anti-COVID-19 vaccine dose. After 3 weeks he showed the clinical signs of polymyalgia rheumatica. The history included mild chronic normocytic normochromic anemia and hypogammaglobulinemia, osteoarthritis disease, livedo reticularis, hypercholesterolemia, and arterial hypertension. Despite prolonged treatment with NSAIDs and dexamethasone, the disease evolved into remitting seronegative symmetrical synovitis with pi [...]

by Roy G Beran

Received: 30 November 2022;  Published: 13 February 2023;  doi: 10.21926/obm.geriatr.2301223

This paper reviews the relationship between RBD and PD and the pathophysiology. Most RBD patients develop PD within 14 years. PD pathophysiology is α-synucleinopathy with dopamine degeneration in nigrostriatal pathways. RBD pathology is poorly understood. Anomalies suggest RBD and PD are different, evidenced by smoking. RBD and PD are associated with glucocerebrosidase gene mutations (GBA gene), suggesting RDB with GBA gene mutation predicts PD. PET imaging, assessing vesicular monoamine transporter 2 (VMAT2), inde [...]

by Gabriele Saretzki

Received: 21 May 2025;  Published: 09 September 2025;  doi: 10.21926/obm.geriatr.2503324

Telomeres are repetitive structures at the ends of linear chromosomes. Due to incomplete DNA replication at the end of linear DNA molecules, the so called “end replication problem”, telomeres shorten consecutively during cell division. In addition, telomere sequences are highly susceptible to oxidative stress damaging telomeres and resulting in their dysfunction even in non-dividing cells. Telomere shortening has been identified as one of the underlying causes for replicative senescence that can also contribute to [...]

by Julia Baumann  , Eva Bönzli  , Franziska Wandrey  and Torsten Grothe

Received: 09 December 2024;  Published: 03 April 2025;  doi: 10.21926/obm.geriatr.2502305

The complex process of skin aging results in noticeable changes, including decreased collagen content, reduced elasticity, and decreased hydration. Interventions to preserve or restore collagen, a key structural protein, may help counteract these signs. The concept of "beauty from within” through nutritional supplements is of growing interest, particularly the use of plant-based alternatives to animal-derived or synthetic collagen. This study investigated the anti-aging potential of an extract from Moldavian dragon [...]

by Giuseppe Cocco  and Stefano Pandolfi

Received: 27 July 2023;  Published: 11 October 2023;  doi: 10.21926/obm.geriatr.2304253

Both from a healthcare and a socioeconomic perspective, research on senescence is increasingly essential. Indeed, in industrialized countries, the increased human longevity confronts medicine with many old patients with age-related pathologies. The paper reviews the biological theories on aging, the impact of reactive oxygen species, telomers, epigenetics, and genetics (e.g., gerontogenes) on-age-related pathologies. Also, the paper reviews available and under research therapeutic approaches (e.g., senolytics) aime [...]

by Vikas Dhikav  , Pankaj Kumar  and Praveen Kumar Anand

Received: 23 August 2022;  Published: 23 November 2022;  doi: 10.21926/obm.geriatr.2204214

Various grades of cognitive impairment generally occur in older adults over the age of 55, where cardiovascular risk factors such as diabetes and/or hypertension, coronary artery disease, or cerebrovascular accidents are also common. Cognitive impairment occurs in various forms, from mild or amnesia such as forgetting today's date to more ominous and progressive forms, such as frank dementia. Over 5 million people worldwide suffer from dementia, most of whom live in low- and middle-income countries. It has been env [...]

by OBM Geriatrics Editorial Office

Received: 01 July 2022;  Published: 03 July 2022;  doi: 10.21926/obm.geriatr.2203201

by Howard Litwin  and Bracha Erlich

Received: 26 June 2022;  Published: 26 December 2022;  doi: 10.21926/obm.geriatr.2204217

This study examined the correlates of change in the depressed state among people aged 65 and older during the SARS-CoV-2 pandemic, particularly the effects of crucial pandemic-related variables. Data were drawn from the longitudinal Survey of Health, Ageing and Retirement in Europe (SHARE), including information obtained from two special pandemic-related telephone interviews (N = 18, 266). The analysis regressed depressed state soon after the outbreak (T1) and again a year later (T2), on four pandemic-related varia [...]

by Weiyun Chen  , Zhanjia Zhang  , Bruno Giordani  and Janet L. Larson

Received: 03 July 2022;  Published: 26 December 2022;  doi: 10.21926/obm.geriatr.2204218

Physical activity is essential to delaying cognitive decline and preventing cognitive impairment in older adults. We designed and implemented two-level 4Active intervention for older adults living in retirement communities. This study aimed to examine the effectiveness of the 4Active intervention in increasing physical activity and cognitive function in older adults. Fifty-eight eligible older adults with a mean age of 83.83 years (76.3% females) living in two retirement communities voluntarily participated in this [...]

by Giuseppe Cocco  and Stefano Pandolfi

Received: 07 February 2022;  Published: 16 June 2022;  doi: 10.21926/obm.geriatr.2202200

Syncope is characterized by a transient and rapid loss of consciousness for a short duration, with full spontaneous recovery within minutes. Syncope causes up to 2% of all emergency medical consultations. The incidence of syncope is similar in men and women, is higher in old patients (slightly higher in old women). The prevalence of syncope is up to 23% for the institutionalized elderly. In elderly patients, syncope often presents atypically, such as with falls; these patients might also have difficulty recalling e [...]

by Kimberly Bader  , James J. Lah  , Allan I. Levey  , Greg J. Esper  , Whitney Wharton  and Joe R. Nocera

Received: 27 December 2021;  Published: 08 September 2022;  doi: 10.21926/obm.geriatr.2203203

Individuals with Alzheimer’s disease (AD) and Mild Cognitive Impairment (MCI) have increased gait disturbances throughout disease progression. However, an understanding of gait impairment and progression in early versus late AD is lacking. Further, the longitudinal progression of gait impairment in AD as well as in those with MCI that transition to AD is lacking. Understanding gait pathology and progression of gait impairment is critical for implementation of strategies that could limit the high prevalence of gait [...]

by Laura Borth  and Meredith Ponder Whitmire

Received: 31 March 2023;  Published: 17 August 2023;  doi: 10.21926/obm.geriatr.2303246

Malnutrition is a problem that is often not identified in hospitals as 8% of hospital patients are diagnosed but malnutrition is estimated to affect 20-50% of patients. Federal programs such as Joint Commission accreditation and the new, optional, global malnutrition composite score from CMS may improve inpatient malnutrition diagnosis, but there may be an opportunity to do more from a regulatory side. It’s unknown how many states are considering malnutrition from this standpoint. The study’s goal was t [...]

by Serena A. Schade  , Julia O’Hanlon  and Elizabeth Orsega-Smith

Received: 09 June 2025;  Published: 12 September 2025;  doi: 10.21926/obm.geriatr.2503326

Senior centers serve as community anchors for the approximately 57.8 million older adults in the U.S., offering a range of health promotion programs, including exercise classes. This study examined how the type of exercise programs at senior centers influences older adults’ health (mental, physical, and quality of life) and how baseline physical activity levels may influence these changes as part of a statewide health promotion program evaluation in senior centers in Delaware. The exercise programs offered were bas [...]

by Melissa Scollan-Koliopoulos  , Donna Naturale  , Brynn Mahurter  , Sara Curren  and Ryan J. Koliopoulos

Received: 03 February 2024;  Published: 29 May 2024;  doi: 10.21926/obm.geriatr.2402280

There is not enough information regarding the impact of stigma associated with a. diagnosis of diabetes in aging older adults. Perceptions of diabetes are passed down generationally and may be influenced by mainstream societal perceptions at the time the perception is shaped. This is known as a multigenerational legacy of diabetes for those with whom the perceptions are shaped within families when a hereditarily predisposed condition occurs. In this study, participants over the age of (n = 88) 60 years old were adm [...]

by Lucy Keers  , Claudia Lee  , Samara White  and Tammie Lee Demler

Received: 18 February 2025;  Published: 29 May 2025;  doi: 10.21926/obm.geriatr.2502313

Pleural effusions are defined as accumulations of fluid in the pleural cavity surrounding the lungs. They are often secondary outcomes of underlying conditions, such as congestive heart failure, malignancy, or pneumonia. Acute cases of COVID-19 pneumonia have been linked to episodes of pleural effusion, but these cases are often rare. In this report, we analyze a case of pleural effusion in a 71-year-old female patient who had been declining after a recent COVID-19 infection and later died in the hospital. It is no [...]

by Vladimir N. Gorchakov  , Kirill M. Nicolaychuk  , Olga V. Gorchakova  , Georgi A. Demchenko  and Bayan A. Nurmakhanova

Received: 09 July 2023;  Published: 01 November 2023;  doi: 10.21926/obm.geriatr.2304257

Lymph nodes are prioritized in protecting and ensuring endoecological safety at different periods of life, especially in retirement age. It destabilizes the structure and function of the lymphatic system and organs when aging increases the risk of comorbid conditions. This is a sign of age-related pathology. Improving lymph node function is an essential task in integrating gerontology and lymphology. The solution to this problem is possible with the help of a phytotherapeutic agent, which involves the evaluation of [...]

by Gohar Azhar  , Melodee Harris  , Laura Hays  , Patricia Savary  , Regina V. Gibson  , James R Perry  , Karen Coker  , Amanda Pangle  , Kenneth Alderson  and Jeanne Wei

Received: 08 January 2024;  Published: 06 March 2024;  doi: 10.21926/obm.geriatr.2401272

The COVID-19 pandemic caused abrupt changes in daily routines, social connections, and ways of life. It is yet unknown the full impacts these extended changes have had on the long-term mental well-being of those who shared this global experience. As a contribution to our overall understanding of this phenomena, this study explored the effects of the COVID-19 pandemic on the mental well-being of older adults in the Southern United States. Secondary data analyses were performed using the COVID-19 Emotional Impact Sur [...]

by Harnish P Patel  , Faidra Laskou  and Elaine M Dennison

Received: 15 February 2024;  Published: 23 January 2025;  doi: 10.21926/obm.geriatr.2501296

Sarcopenia is characterised by progressive and generalised decline in muscle strength, function, and muscle mass. Now recognised as a muscle disease, it is highly prevalent in older adults, with estimates of up to 30% in some populations. Sarcopenia has a complex multifactorial aetiology, including cellular and molecular changes, chronic disease, lower physical activity as well as nutritional deficiency. Sarcopenia is associated with a range of adverse physical and metabolic outcomes leading to disability, morbidit [...]

by Dennis Rosenberg  and Sharon Shiovitz-Ezra

Received: 13 March 2023;  Published: 11 July 2023;  doi: 10.21926/obm.geriatr.2303242

The current study aimed to examine the link between cross-temporal patterns of care provision and loneliness in older adults. Social capital and caregiver stress perspectives served as a theoretical framework for the study. The data were obtained from the two COVID-19 waves of the Survey of Health, Ageing, and Retirement in Europe (SHARE) conducted in 2020 and 2021. The data were analyzed using logistic regression models. The analytical sample consisted of 48,722 older adults residing in Europe and Israel. The anal [...]

by David G Smithard  and John Mirams

Received: 20 February 2023;  Published: 24 August 2023;  doi: 10.21926/obm.geriatr.2303247

As the medical world continues to search for ways of improving the swallowing of many millions of Dysphagia sufferers around the world, this paper is devoted to presenting the case for carbonated water to be considered as a potential solution for many. The effectiveness of carbonated water (CW) in the rehabilitation of Dysphagia has been studied periodically over the last thirty years and some significant positive results have been recorded – but it is now proposed that further research should be directed to examin [...]

by Claire Robson  , Jen Marchbank  and Gloria Gutman

Received: 27 November 2023;  Published: 31 January 2024;  doi: 10.21926/obm.geriatr.2401267

Though research suggests that older adults belonging to gender and sexual minorities (GSM) are at greater risk of abuse and neglect, more needs to be done to investigate this situation, provide solid data, offer support to survivors and better inform those providing services. This article reports on a participatory action research project in which nine older adults with lived experience of abuse were interviewed, as were the seniors’ programmer from our community partner organization and a trauma counsellor who sup [...]

by Alicia Morales  , Vania Cataldo  , Diego Berrios  , Ana Beatriz  , Karen Danke  , Gisela Jara  , Fabiola Werlinger  , Mauricio Baeza  , Viviana García Ubillo  and Jorge Gamonal

Received: 03 November 2024;  Published: 11 June 2025;  doi: 10.21926/obm.geriatr.2502316

It has been suggested that an individual's overall functional capacity gradually declines with age. It has been reported that a decline in oral functionality increases the risk of sarcopenia and frailty, which contributes to the decrease in functional capacity. In Chile, the Preventive Medical Examination for Older Adults (EMPAM) is used to assess the functionality of that population; however, this examination does not include an evaluation of oral functionality. To address this gap, the Preventive Dental Examinati [...]

by M. Lourdes Mourelle  and Leonel Pereira

Received: 26 January 2025;  Published: 17 April 2025;  doi: 10.21926/obm.geriatr.2502308

The increasing consumer demand for cosmetic products has led to the widespread use of synthetic substances, which are inexpensive and readily available but can sometimes harm the skin and body. Examples include hydroxybenzoic acid esters (parabens) and phthalates, which are considered endocrine disruptors, and synthetic fragrances that may cause irritation or allergies. Consequently, there has been a shift in consumer preferences towards natural cosmetic products. In response to this demand and the expanding market [...]

by Karen A. Roberto  , Pamela B. Teaster  and Imogen Fua

Received: 23 August 2024;  Published: 09 January 2025;  doi: 10.21926/obm.geriatr.2501294

The purpose of this descriptive study was to understand the nature, extent, and challenges confronted by APS programs in the United States in providing services to older clients affected by opioids. The study design involved a two-step process: Phase I involved telephone interviews with state-level Adult Protective Services administrators from 11 states considered to be “hot-bed states” for the opioid epidemic. Findings from the administrator interviews informed questions for Phase II telephone interviews with indi [...]

by Robert Beringer  , Paneet Gill  , Gloria Gutman  and Brian de Vries

Received: 31 July 2022;  Published: 17 November 2022;  doi: 10.21926/obm.geriatr.2204213

Disasters such as the COVID-19 pandemic exact a toll on vulnerable populations in terms of morbidity and mortality, but they also provide opportunities for personal growth and development and demonstration of personal and collective resiliency. This inductive thematic analysis explores self-perceived negative and positive impacts of the COVID-19 pandemic on 2994 Canadians aged 55+. Data derive from response to two open-ended questions included in a national online survey (View Survey (sfu.ca)) conducted between Aug [...]

by Jasmin Hundal  and Mariam AlHilli

Received: 19 August 2024;  Published: 19 March 2025;  doi: 10.21926/obm.geriatr.2501304

Elderly patients with ovarian and pancreatic cancer frequently experience malnutrition and sarcopenia, which negatively impact treatment tolerance, functional outcomes, and survival. The increasing use of neoadjuvant chemotherapy in this population necessitates structured interventions to mitigate these challenges. While prehabilitation has shown promise in enhancing treatment tolerance and quality of life, its role during chemotherapy remains underexplored. This prospective study evaluates the feasibility and impa [...]

by Tammy S. Martin

Received: 17 December 2023;  Published: 19 February 2024;  doi: 10.21926/obm.geriatr.2401269

Clinicians caring for patients, especially those with chronic diseases or older adults, need to recognize the value of being able to transition away from aggressive care when appropriate and focus on a more palliative approach. Research has shown that patients want to have goals of care discussions and maintain autonomy at the end of life. These goals of care discussions can be challenging, and clinicians must prioritize and develop this skill in order to provide their patients with what they may need most. Being a [...]

by Elsa Abreu  , Catarina Simões  and Rita Figueiredo

Received: 02 March 2024;  Published: 31 July 2024;  doi: 10.21926/obm.geriatr.2403283

Skin is the largest organ of the human body. Skin changes can result from natural ageing, as well as from acute or chronic diseases and failure of body systems. Various types of wounds are identified in Palliative Care, and terminal pressure ulcers are often incorrectly classified. This case study highlights the importance of recognizing skin ulcers in patients’ last hours and days of life as a diagnostic indicator for impending death. The first focus of nursing care was pain management and maintaining skin integri [...]

by Ana Santos  , Elsa Abreu  , Márcia Assunção  , Catarina Simões  and Rita Figueiredo

Received: 31 January 2025;  Published: 28 May 2025;  doi: 10.21926/obm.geriatr.2502312

The growing number of individuals with palliative care needs has led to an increased demand for specialized palliative care teams.. However, these teams often struggle to meet the demand, requiring all nurses to recognize and provide appropriate care during a patient’s last hours and days of life (LHDL). This case report aims to highlight the importance of identifying the LHDL and implementing individualized and adjusted care plans based on the 10/40 model of care. A descriptive-reflective case report following the [...]

by Diana Viafara  , Ana L. Jaramillo-Sierra  and Laura Sofía Vega-Plazas

Received: 15 June 2024;  Published: 12 January 2025;  doi: 10.21926/obm.geriatr.2501295

This research article aims to address the critical gap in understanding intimate partner violence (IPV) among older women, particularly those over 60 years of age, in Colombian society. The study explores how IPV manifests during the later stages of life, providing insights specific to this age group. The research used qualitative methodology with 14 urban women who had experienced intimate partner violence in their later life. The study revealed that psychological violence was the most common type of abuse among o [...]

by Cesar Augustus Zocoler de Sousa  , Ana Paula Renno Sierra  , Giscard Humberto Oliveira Lima  , Bryan Steve Martínez Galán  , Hermes Vieira Barbeiro  , Heraldo Possolo de Souza  and Maria Fernanda Cury-Boaventura

Received: 20 August 2024;  Published: 28 February 2025;  doi: 10.21926/obm.geriatr.2501301

This study compared markers of muscle damage and myokines between adult and middle-aged runners before and after the marathon. Seventy-four male runners: 48 adults aged 30-44 years (AA group), and 26 middle-aged individuals aged 45-59 years (MA group) participated of the study. Blood samples were collected 24 hours before, immediately after, 24 hours and 72 hours after the marathon to measure skeletal and cardiac muscle damage markers (CK, LDH, troponin, and proBNP) and myokines (IL-6, IL-15, decorin, BDNF, GDF-15, [...]

by Andrea Bellieni  , Beatrice Di Capua  , Emanuele Rocco Villani  , Luca Tagliaferri  , Domenico Fusco  , Maria Antonietta Gambacorta  , Francesco Presta  , Serena Bracci  , Vincenzo Valentini  , Francesco Landi  and Giuseppe Ferdinando Colloca

Received: 17 November 2022;  Published: 13 June 2023;  doi: 10.21926/obm.geriatr.2302238

New technologies, aging-related changes, and evolution in patients' needs have led to a new scenario in all oncological fields in front of which we have to move on. Technological progress has made it possible to increase the number of patients treated, including elderly patients and generally those at higher risk of toxicity. However, this scenario has led to new problems requiring new skills to be addressed. For this reason, Gemelli-ART (Advanced Radiation Therapy) of Fondazione Policlinico Universitario A. Gemell [...]

by Joseph S. D'Arrigo

Received: 25 March 2023;  Published: 04 August 2023;  doi: 10.21926/obm.geriatr.2303244

Early changes in systemic vascular stiffness and endothelial function can contribute to altered cerebrovascular hemodynamics and impaired cognitive function; additionally, these vascular changes point to potential targets for prevention and treatment strategies in people with mild cognitive impairment. Although the pathogenic mechanisms underlying these vascular changes are heterogeneous and complex, one common feature is the development of cerebral blood flow (CBF) dysregulation, resulting in chronic cerebral hypo [...]