Table of Content

Open Access Interview

An Interview with Dr. Pietro Gareri

Received: 02 July 2025;  Published: 02 July 2025;  doi: 10.21926/obm.geriatr.2503318

652 2527

Open Access Research Article

Technology Support to Enable People with Severe Intellectual Disability and Blindness to Carry Out Occupational Activities and Transition Between Them Independently

Received: 14 July 2025;  Published: 09 October 2025;  doi: 10.21926/obm.neurobiol.2504303

Abstract

People with severe intellectual disability and blindness tend to perform only simple occupational activities and are mostly unable to transition between those activities. This inability makes their level of occupation independent of staff support fairly limited. Technology-aided programs may be one of the few opportunities available to increase their independent occupation. This study assessed one such program designed to (a) monitor the participants’ responses and guide them to transition to a new activity once th [...]

609 2508

Open Access Original Research

Cultural Distance, Host Acculturation Orientation, and Psychological Adaptation among African International Students at Portuguese Universities

Received: 10 July 2025;  Published: 24 October 2025;  doi: 10.21926/obm.icm.2504045

Abstract

International students represent a significant sojourner group. Increasing international student numbers makes it ever more relevant to understand the determinants of their psychological adaptation. This research investigates the question of how perceived cultural distance (PCD) impacts acculturation variables (social contact with host nationals and host national identity) and outcomes such as saudade and life satisfaction among African international students. The sample comprised 422 college students (195 from Ang [...]

494 2427

Open Access Review

Contribution of Solar Energy to Buildings’ Energy Demands: A Review

Received: 27 June 2025;  Published: 12 January 2026;  doi: 10.21926/aeer.2601002

Abstract

Buildings account for a significant portion of global energy consumption, estimated at 30-40%, and also contribute to greenhouse gas emissions. Energy consumption in a building is mainly thermal (natural gas) and electrical. This energy is usually used for heating water, cooking, illumination, ventilation and air conditioning, powering appliances, floor heating, and other activities. These activities were examined, and their substitution by solar-based energy sources was reviewed. To achieve this objective, an exte [...]

824 2414

Open Access Original Research

Immunologic Response after COVID-19 Vaccination in Heart Transplant Recipients

Received: 30 June 2025;  Published: 21 October 2025;  doi: 10.21926/obm.transplant.2504259

Abstract

To date, all large-scale randomized controlled trials for COVID-19 vaccines have excluded solid organ transplant recipients; therefore, the effectiveness and safety of COVID-19 vaccines in preventing coronavirus infection using COVID-19 vaccines in patients with heart transplants have not been sufficiently studied. This paper presents the characteristics of humoral and cellular immunity in heart transplant recipients following vaccination against coronavirus infection. The study group consisted of 40 patients who u [...]

557 2399

Open Access Editorial

Acknowledgement to Reviewers of OBM Geriatrics in 2024

Received: 02 January 2025;  Published: 02 January 2025;  doi: 10.21926/obm.geriatr.2501293

Abstract

The editors of OBM Geriatrics would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2024. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal’s editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers can download a certificate of recognition directly from our submission system. Additionally, reviewers can sign up to the Web of S [...]

504 2374

Open Access Perspective

From Vision to Strategy: Expanding Metaversal Integrative Healthcare with DAOs and Blockchain Ecosystems

Received: 26 May 2025;  Published: 26 November 2025;  doi: 10.21926/obm.icm.2504050

Abstract

Legacy, profit-driven organizational structures often lack the adaptability, equity, and innovation required for the evolving complexities of contemporary patient-centered care. They can limit access, constrain options, impose financial burdens, and hinder optimized delivery. Here, we propose a new architecture for metaversal integrative healthcare using decentralized autonomous organizations (DAOs). Blockchain technology and smart contracts underpin equitable, transparent, and resilient health ecosystems beyond in [...]

466 2343

Open Access Original Research

Effects of Trauma, Shame, and Self-Criticism on Hoarding: Comparative Data and Treatment Implications

Received: 31 January 2025;  Published: 01 December 2025;  doi: 10.21926/obm.icm.2504051

Abstract

Severe trauma has a significant impact on self-attitudes and emotions, such as self-criticism and shame, and psychological symptoms. This topic has been more well studied among populations with Trauma and Stress-Related Disorders, but examined to a lesser extent in other clinical populations where adverse life events and potentially traumatic events are highly prevalent, such as Hoarding Disorder. The current study examined trauma exposure, and the relationships between trauma, self-criticism, shame, and symptom se [...]

741 2329

Open Access Research Article

Investigating Mental Health Literacy and Its Relationship with Addiction to Social Networks among Allied Medical Sciences Students

Received: 24 June 2025;  Published: 19 November 2025;  doi: 10.21926/obm.neurobiol.2504311

Abstract

The widespread use of social media among college students has become a significant concern due to its potential impact on mental health and addictive behaviors. Social media platforms, while offering numerous benefits, can also foster environments that contribute to addiction, depression, and anxiety. College students, in particular, are vulnerable to these effects due to their high levels of social media engagement and the pressures of academic life. Mental health literacy, which involves understanding and managin [...]

548 2313

Open Access Research Article

Sleep and Mood as Mechanisms Linking Trauma Exposure to Alcohol Use in South African First Responders: A Serial Mediation Analysis

Received: 15 June 2025;  Published: 14 November 2025;  doi: 10.21926/obm.neurobiol.2504308

Abstract

First responders are routinely exposed to traumatic events in the line of duty, placing them at heightened risk for adverse mental health outcomes, including substance use. This study investigated the psychological mechanisms linking trauma exposure to alcohol use, specifically examining the serial mediating roles of insomnia and depression. A sample of 429 first responders (309 police officers and 120 paramedics) from the Western Cape, South Africa, completed an online survey comprising the Life Events Checklist-5 [...]

552 2303

Open Access Interview

An Interview with Prof. Rosita Gabbianelli

Received: 24 August 2025;  Published: 27 August 2025;  doi: 10.21926/rpn.2503017

Abstract

An Interview with Prof. Rosita Gabbianelli

481 2289

Open Access Review

Exposure to Mycotoxins: Neurological Disorders and Psychiatric Manifestations

Received: 27 October 2025;  Published: 09 February 2026;  doi: 10.21926/obm.neurobiol.2601322

Abstract

Mycotoxins, toxic secondary metabolites produced by fungi and molds, have negative health impacts on both humans and animals. They are commonly found in foods such as nuts, coffee, cereals, and grains, particularly in regions with warm, humid climates. Among the most prevalent mycotoxins in these foods are aflatoxin B1, ochratoxin A, zearalenone, patulin, and deoxynivalenol (DON). The presence of mold capable of producing mycotoxins within food contributes to an elevated risk of various illnesses, including those r [...]

892 2262

Open Access Original Research

Environmental Risk Assessment of Antiretrovirals Consumed in Belo Horizonte, Brazil

Received: 09 June 2025;  Published: 04 December 2025;  doi: 10.21926/aeer.2504034

Abstract

The development and utilization of pharmaceuticals, notably antiretrovirals (ARVs), have significantly enhanced both human quality of life and life expectancy. Nevertheless, the excretion of these compounds into aquatic environments, often exacerbated by inadequate sanitation infrastructure, poses considerable risks to biota. This investigation evaluated the environmental impact of 14 ARVs consumed within the municipality of Belo Horizonte (BH), Brazil. The assessment employed the Environmental Risk Assessment (ERA [...]

693 2249

Open Access Original Research

Evaluation of Full Blood Count–Derived Inflammatory Indices (SII, SIRI, PIV, NLR) in Behçet’s Disease Patients and Healthy Controls

Received: 01 October 2025;  Published: 24 November 2025;  doi: 10.21926/obm.genet.2504318

Abstract

This study investigated three novel complete blood count–derived inflammatory biomarkers Systemic Immune-Inflammation Index (SII), Systemic Inflammation Response Index (SIRI), and Pan-Immune-Inflammation Value (PIV) and their relationship with clinical features of Behçet’s Disease (BD). Established markers, including neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and monocyte-to-lymphocyte ratio (MLR), were also analyzed. Seventy HLA-B51–positive BD patients and 114 HLA-B51–negative healt [...]

513 2246

Open Access Original Research

When the Psychological Weight of the Burden Affects the Physical Weight of Caregivers of Older Patients in a French Memory Hospital (Lille, France)

Received: 23 May 2025;  Published: 10 October 2025;  doi: 10.21926/obm.geriatr.2504328

Abstract

Caring for patients with neurocognitive disorders (NCD) can be challenging for caregivers, with the risk of malnutrition. Observational, retrospective, monocentric study carried out with patient-caregiver dyads admitted to the Memory Day Hospital of the Gerontology Center of the University Hospital of Lille over 6 months in 2023. Our objectives were to identify the socio-characteristics of caregivers who had recently experienced a variation in their weight, their degree of fatigue (using the Fatigue Numerical Ratin [...]

632 2211

Open Access Original Research

Mindful Attention and Awareness Prospectively Predicts Stress in Daily Life: A Multilevel Modeling Approach

Received: 17 June 2025;  Published: 09 October 2025;  doi: 10.21926/obm.icm.2504042

Abstract

Chronic stress increases a person’s vulnerability for physical and mental health conditions that take root in the “common soil” of inflammation. Dispositional, or trait, mindfulness has been identified as a protective factor against perceived stress. However, the theory that trait mindfulness can prospectively predict lower perceived stress in natural settings has yet to be thoroughly tested. The current study used a daily diary prospective design to observe perceived stress in response to difficult events. Partici [...]

492 2176

Open Access Original Research

Barriers Encountered When Implementing a Community Evidence-Based Fall Prevention Program

Received: 11 June 2025;  Published: 05 November 2025;  doi: 10.21926/obm.geriatr.2504330

Abstract

Falls and fall-related injuries are one of the leading causes of death among older adults aged 65+ in the United States. Americans’ life expectancy has increased and fall risk grows with age. While several evidence-based fall prevention programs are utilized to decrease fall risk among community-dwelling older adults, little research focuses on challenges or strategies related to sustained fall prevention program implementation. The purpose of this multi-method descriptive study was to assess fall risk outcome chan [...]

577 2132

Open Access Original Research

GHG Emissions Management in Urban Areas by Interactive Road Traffic Control: Application of Artificial Intelligence

Received: 04 June 2025;  Published: 03 December 2025;  doi: 10.21926/aeer.2504033

Abstract

The rising pollution levels in congested urban areas pose a serious threat to human health. Many solutions have been proposed to control and reduce gas emissions from road traffic, with results that are not entirely satisfactory. The adoption of new techniques and methodologies for early detection of pollutant emissions may enable effective management and control of road traffic contamination. The proposed method introduces an interactive protocol that facilitates communication between the traffic control center an [...]

556 2059

Open Access Original Research

Rapid Green Synthesis of Silver Nanoparticles and Alginate-Silver Nanocomposite Beads Using Mashmoom (Ocimum basilicum), a Bahraini Household Medicinal Herb

Received: 16 June 2025;  Published: 17 November 2025;  doi: 10.21926/rpm.2504017

Abstract

The study focuses on the rapid green synthesis of silver nanoparticles (AgNPs) and alginate-silver nanocomposite (Alg-AgNc) beads using sweet basil or Mashmoom (Ocimum basilicum), a common household medicinal herb in Bahrain. The aqueous extract of mashmoom was used as a reducing and stabilizing agent in the reduction of the precursor salt, silver nitrate, and formation of stable AgNPs. The Alg-AgNc beads were prepared by ionotropic gelation of sodium alginate-AgNPs solution in calcium chloride. A strong surface pl [...]

582 2042

Open Access Original Research

Framework for the Secured Integration of Renewable Energy into Power Systems

Received: 11 June 2025;  Published: 05 December 2025;  doi: 10.21926/jept.2504016

Abstract

This research introduces a blockchain framework to improve security and transparency for the use of renewable energy in power systems. The framework utilizes a permissioned blockchain architecture and IoT-based real-time monitoring to ensure data integrity and confidentiality and support efficient peer-to-peer (P2P) energy trading. Compared with traditional centralized energy management systems, the proposed design increases transaction security by 35%, decreases verification wait times by 28%, and decreases the ri [...]

580 2029

Open Access Commentary

Targeting Neuroinflammation in Difficult-to-Treat Depression: From Anti-Inflammatory Agents to Multi-Target Immunopsychiatric Interventions

Received: 30 July 2025;  Published: 27 January 2026;  doi: 10.21926/obm.neurobiol.2601321

Abstract

Difficult-to-treat depression (DTD) with inflammatory features (e.g., hs-CRP ≥3 mg/L and/or elevated IL-6) may represent a clinically and biologically distinct presentation characterized by chronicity, functional impairment, prominent cognitive-motivational symptoms, and suboptimal response to conventional treatments. Classical anti-inflammatory strategies (e.g., COX-2 inhibitors or cytokine-targeting biologics) have shown signals of efficacy in selected biomarker-enriched subgroups; however, overall evidence remai [...]

689 2015

Open Access Original Research

A Frequency Analysis of the Professional Quality of Life of NeuroAffective Relational Model (NARM) Therapists after NARM Training

Received: 25 July 2025;  Published: 04 January 2026;  doi: 10.21926/obm.icm.2601001

Abstract

Research shows that trauma therapists often experience secondary trauma, which can lead to secondary traumatic stress, compassion fatigue, and burnout. Trauma-informed care training has shown promise in enhancing practitioners' professional quality of life, particularly for those regularly exposed to trauma. To our knowledge, no prior studies have examined the training outcomes of NeuroAffective Relational Model (NARM) therapists on professional quality-of-life indicators. This cross-sectional observational study a [...]

512 1990

Open Access Original Research

Differential Expression of MiR-21 and MiR-19 in Biliary Atresia: Diagnostic Potential and Therapeutic Implications

Received: 24 May 2025;  Published: 26 November 2025;  doi: 10.21926/obm.genet.2504319

Abstract

Biliary atresia (BA), a severe pediatric liver disease of unknown etiology, causes neonatal jaundice, progressive cholestasis, and life-threatening liver fibrosis. Emerging evidence suggests microRNAs (miRNAs) – small non-coding RNAs that regulate gene expression by binding target mRNAs may play a role in BA pathogenesis. Circulating miRNAs have shown diagnostic potential for various diseases, prompting our investigation of miR-21 and miR-19 as potential biomarkers in BA. We conducted a case-control study comparing [...]

664 1964

Open Access Review

Risk Assessment in Clinical Histocompatibility Testing: Challenges, Strategies, and Future Directions

Received: 15 July 2025;  Published: 25 November 2025;  doi: 10.21926/obm.transplant.2504260

Abstract

Though the role of clinical histocompatibility testing is fundamental to successful transplant, systematic risk assessment and mitigation strategies remain underutilised in this domain. This review addresses risk identification, analysis, and control measures across the pre-analytical, analytical, and post-analytical phases of clinical histocompatibility testing, in line with international standards such as ISO 15189:2022. A structured, risk-based quality management system (QMS) is imperative for ensuring accurate [...]

557 1936

Open Access Original Research

Genetic Differentiation of Populations of Three Megalopolises by DNA Markers of the Y-Chromosome in Connection with the Problem of Developing Genetic Databases

Received: 04 June 2025;  Published: 12 January 2026;  doi: 10.21926/obm.genet.2601324

Abstract

The purpose of the study was to consider the distribution of Y-chromosome DNA markers in samples from the populations of the three largest megalopolises (Moscow, Saint Petersburg, and Novosibirsk) in the Russian Federation, in the context of developing genetic databases. The study aimed to compare the frequency profiles of 18 Y-chromosome STRs (Short tandem repeats) and the level of genetic differentiation. Based on FST estimates for the distribution of these 18 Y-chromosome STRs, the senior generations of Moscow a [...]

568 1933

Open Access Review

Administration of the Effects of Wireless Electromagnetic Fields on Living Tissues in Sustainable Urban Ecosystems

Received: 07 October 2025;  Published: 17 December 2025;  doi: 10.21926/rpse.2504017

Abstract

A relevant objective of managing an electromagnetic (EM) device is to improve its expected results and reduce its undesirable side effects. In this context, this paper aims to evaluate the interest of the two One Health and Responsible Attitude methods in the daily practice of wireless transmission (or transfer) in EM energy devices. These approaches are respectively linked to device eco-design and optimization, as well as to the protection of biodiversity and ecosystems against device side effects related to EM fi [...]

648 1927

Open Access Research Article

Integrating Small-Scale Geothermal into a Mini-Grid to Improve Electricity Access in Nigeria

Received: 31 July 2025;  Published: 12 January 2026;  doi: 10.21926/jept.2601002

Abstract

Increasing local energy access in developing countries, particularly in off-grid regions where mini-grids are often overloaded, remains a critically underexplored area in energy transition. These regions often face significant technical and economic challenges, such as low generation capacity, high energy costs, limited energy access, and heavy reliance on diesel fuels. This study explores capacity expansion by integrating small-scale geothermal energy into such a mini-grid system to enhance the local energy supply [...]

723 1884

Open Access Original Research

iRest™ Meditation Webinar Series Addresses Depression Symptoms in Older Adults

Received: 09 August 2025;  Published: 07 January 2026;  doi: 10.21926/obm.icm.2601004

Abstract

Older adults in the U.S. have higher rates of depression, stress, and chronic diseases. There is an urgent need for effective interventions to reduce depressive symptoms and enhance overall health and well-being. Meditation presents an appealing therapeutic option due to its cost-effectiveness, minimal risks, ease of use, and active patient involvement, with growing evidence indicating its effectiveness in reducing depressive symptoms. Online platforms may provide more accessible options for meditation intervention [...]

613 1876

Open Access Editorial

Biochar and Circular Economy Approaches in Environmental Sustainability

Received: 21 December 2025;  Published: 24 December 2025;  doi: 10.21926/aeer.2504035

Abstract

The rising concerns of soil erosion, organic waste generation and global warming have shown the need to address them through multifaceted methods that transcend conventional linear models of resource utilization. Circular economy is a regenerative model that is anchored on caring about waste valorisation, resource effectiveness and environmental fortitude. In this paradigm, biochar has been developed as a multifunctional compound capable of integrating waste management, soil rehabilitation, climate control and rene [...]

656 1852

Open Access Short Review

The Role of Nitrogen-Containing Compounds in Chemical Neuroscience: Implications for Drug Development

Received: 03 May 2025;  Published: 04 January 2026;  doi: 10.21926/obm.neurobiol.2601318

Abstract

The study explores the crucial biological function of nitrogen in cyclic and acyclic structures with resonance potential, including tetrazoles, pyrroles, piperidines, and carbamates, within the realm of chemical neuroscience. It highlights the importance of these compounds for their biological properties and their ability to cross the blood-brain barrier (BBB) to reach the central nervous system (CNS). The study emphasizes the necessity for neurochemical drugs, like morphine, to effectively cross the BBB, as modifi [...]

664 1835

Open Access Review

The Relationship between Hereditary Predisposition and Epigenetic Mechanisms of Schizophrenia Development

Received: 17 August 2025;  Published: 08 December 2025;  doi: 10.21926/obm.neurobiol.2504314

Abstract

Schizophrenia is a multifactorial mental disorder associated with multiple SNPs in the human genome, located mainly outside the annotated protein-coding genes. These regions contain a large number of retroelements, which drive epigenetic regulation. Therefore, it is suggested that schizophrenia-associated SNPs exert their influence on the pathological functioning and activation of retroelements, which contribute to epigenetic imbalance in the brain with the development of pathological processes. A reflection of the [...]

554 1806

Open Access Research Article

The Nociceptive Glio-Neural Complex as a Histoanatomical Substrate of Acupuncture Meridians?

Received: 11 November 2024;  Published: 09 November 2025;  doi: 10.21926/obm.icm.2504048

Abstract

Morphological evidence of peripheral glial cell involvement is lacking. Therefore, we investigated the presence of Schwann cells in acupuncture meridians. Eight legs of four unembalmed cadavers were used. Along the stomach meridian and a control meridian, quadrangular samples were taken from skin to the deep subcutaneous fascia and embedded in paraffin. 5 µm sections were stained for H&E and processed for immunolabeling using antibodies against S100 and NFP, respectively. In the stomach meridian, a large assembly o [...]

496 1804

Open Access Original Research

Advancing Marine Renewable Energy for Island Nations: Design and Development of a 20 kW Floating Kuroshio Turbine (FKT)

Received: 15 September 2025;  Published: 10 December 2025;  doi: 10.21926/jept.2504017

Abstract

Taiwan relies heavily on imported fossil fuels, with over 98% of its energy demand supplied by foreign sources, posing significant challenges to national energy security. To explore alternatives, this study investigates the potential of marine renewable energy by developing a 20 kW floating hydrokinetic turbine prototype designed for deployment in the Kuroshio Current. The research encompasses system design, model validation, and both tank and at-sea testing to evaluate hydrodynamic performance and power generation [...]

578 1752

Open Access Original Research

Technology to Help People with Blindness and Intellectual Disability Manage Indoor Travel: Anticipating and Bypassing Obstacles

Received: 18 August 2025;  Published: 27 November 2025;  doi: 10.21926/obm.neurobiol.2504313

Abstract

Recent work with people with blindness and intellectual disability assessed a technology-aided program intended to help eight participants travel indoor routes to reach relevant destinations. The technology included a smartphone, two barcode readers worn by the participants at their ankles, barcodes displayed at specific points of the travel routes, and a mini speaker. The technology ensured that participants received verbal instructions on how to proceed (e.g., take a left turn, cross from one side to the other of [...]

460 1744

Open Access Commentary

Loneliness, Love and Their Connection: A Commentary

Received: 24 August 2025;  Published: 25 November 2025;  doi: 10.21926/obm.neurobiol.2504312

Abstract

A significant social stigma is associated with loneliness. The prevalence of social isolation, in the dawn of the 21st century points to the growing isolation in America. Lonely people who commonly display negative self-perceptions, show great difficulty to establish social ties, and that may be related to their personal inadequacies, or socially undesirable attributes. Lonely people suffer from a low social perception, painting them as less psychologically adjusted, and not very capable in relating to others. That [...]

556 1731

Open Access Short Review

The Application of Next-Generation Sequencing in Leukemia

Received: 02 May 2025;  Published: 25 December 2025;  doi: 10.21926/obm.genet.2504321

Abstract

Leukemia is a heterogeneous group of hematologic malignancies characterized by the dysfunctional proliferation of white blood cells in the bone marrow. Genetic alterations are important risk factors for the development and progression of leukemia, and their detection is crucial. Although many genetic techniques, including karyotyping, fluorescence in situ hybridization (FISH), and polymerase chain reaction (PCR), have provided valuable information, they all have the limitation of incomplete genomic coverage. The ev [...]

462 1693

Open Access Review

Optimizing Donor Management Strategies for DCD Lung Procurement

Received: 30 June 2025;  Published: 30 December 2025;  doi: 10.21926/obm.transplant.2504261

Abstract

Donation after circulatory death (DCD) offers a vital strategy to expand the donor lung pool; however, DCD lungs are uniquely susceptible to warm ischemic injury during procurement. This chapter reviews evidence-based and emerging donor management strategies aimed at mitigating ischemic damage and optimizing the suitability of DCD lungs for transplantation, encompassing hemodynamic and ventilatory optimization, bronchoscopic clearance, targeted pharmacological interventions, and strategies to minimize transfusion r [...]

469 1673

Open Access Review

Advancing Mathematical Learning in Children and Adolescents with Autism Spectrum Disorder through Serious Games and Educational Robotics: A Mini Review

Received: 04 November 2025;  Published: 10 February 2026;  doi: 10.21926/obm.neurobiol.2601323

Abstract

Mathematical learning often presents persistent challenges for children and adolescents with Autism Spectrum Disorder (ASD) due to differences in Executive Functioning (EF), cognitive flexibility, and symbolic reasoning. These factors can hinder the development of numerical understanding and pre-mathematical reasoning, problem-solving, and abstract thinking, frequently resulting in disengagement and anxiety. In recent years, digital and embodied technologies—particularly Serious Games (SG) and Educational Robotics [...]

568 1656

Open Access Review

Stem Cell-Derived Exosomes: Non-Coding RNA Cargos for Reprogramming the Tumor Immune Microenvironment

Received: 10 October 2025;  Published: 14 January 2026;  doi: 10.21926/obm.genet.2601325

Abstract

Stem cell-derived exosomes (SDEs) have emerged as revolutionary mediators in cancer immunotherapy, offering unprecedented potential to reprogram the immunosuppressive tumor immune microenvironment (TIME). These nano-sized extracellular vesicles, laden with non-coding RNAs (ncRNAs), serve as natural biocompatible carriers, capable of orchestrating immune cell dynamics, stromal remodeling, and tumor cell fate. Unlike their tumor-derived counterparts, which often propagate oncogenic signals, SDEs uniquely harbor immun [...]

529 1647

Open Access Editorial

Points of View on Peer Review and the Potential for AI-Assisted Review

Received: 09 November 2025;  Published: 11 November 2025;  doi: 10.21926/rpse.2504015

500 1643

Open Access Interview

An Interview with Dr. Blanca Hernandez-Ledesma

Received: 28 August 2025;  Published: 09 October 2025;  doi: 10.21926/rpn.2504022

434 1629

Open Access Review

Selenium Supplementation in Rheumatoid Arthritis: Evidence from Controlled Clinical Trials and Mechanistic Insights

Received: 27 October 2025;  Published: 13 February 2026;  doi: 10.21926/rpn.2601002

Abstract

Selenium (Se) is a key micronutrient integrated into selenoproteins such as glutathione peroxidases (GPx), which are responsible for crucial antioxidant and anti-inflammatory mechanisms. Oxidative stress contributes to the immunopathogenesis and chronic joint damage of rheumatoid arthritis (RA), supporting interest in selenium supplementation as an adjunct therapeutic strategy. This review was based on a structured literature search of major biomedical databases and evaluated six controlled clinical trials involvin [...]

703 1579

Open Access Review

Machine Perfusion in DCD Lung Transplantation: Advances in Preservation and Donor Pool Expansion

Received: 30 June 2025;  Published: 21 January 2026;  doi: 10.21926/obm.transplant.2601264

Abstract

To address the pressing shortage of donor lungs, Donation after Circulatory Death (DCD) transplantation has become a vital strategy for expanding the donor pool. Minimizing warm ischemic injury is crucial for optimizing organ viability and function. This review synthesizes current evidence on Normothermic Regional Perfusion (NRP) and Ex-Vivo Lung Perfusion (EVLP) in DCD lung transplantation. Analysis reveals their growing efficacy in minimizing ischemic damage, facilitating organ assessment, and expanding the trans [...]

449 1572

Open Access Research Article

Correlation between the Storage Pattern of Spent Fuel Casks and the Neutron Multiplication Factor

Received: 21 April 2025;  Published: 19 December 2025;  doi: 10.21926/jept.2504018

Abstract

The effective neutron multiplication factor (keff) of a fissile system is a function of space and time f(x, y, z, t), where (x, y, z) are the coordinates of the reference point in space, and t is time. The evidence of the time-dependence of the neutron multiplication factor of a fissile system was published in 2017. The spatial dependence is as important as the time dependence, as interacting arrays of fissile material during storage can lead to an increase in the system (keff). Therefore, evaluation of how the sto [...]

415 1546

Open Access Original Research

Preparation and Properties of Frozen Yoghurt Made from Camel Milk Fortified with Dates and Banana Fruits

Received: 30 July 2025;  Published: 22 December 2025;  doi: 10.21926/rpn.2504026

Abstract

This study was conducted to process frozen yoghurt (FY) from camel milk (CM) flavored with either 5% or 8% banana (B) or dates (D). The mix of FY consists of stirred yoghurt, sugar, Gum Arabic, and banana (Musa lutea) or dates (Phoenix dactylifera). The mix was divided into 4 portions and then each mix was sub-derived into an ice-cream machine and then packed into plastic cups that were stored at -18°C for 5 weeks. The chemical composition and sensory evaluation were conducted weekly. The chemical composition of FY [...]

521 1531

Open Access Review

Red Meat Consumption and Rheumatic Diseases: A Comprehensive Narrative Review

Received: 03 November 2025;  Published: 23 February 2026;  doi: 10.21926/rpn.2601003

Abstract

Dietary factors influence chronic inflammation and immune regulation, potentially affecting the onset and activity of rheumatic disease. Red meat, a major source of protein, heme iron, and saturated fat, has been linked to metabolic and inflammatory disorders, yet its role in rheumatic diseases remains unclear. To comprehensively evaluate the relationship between red-meat consumption and major rheumatic diseases—including rheumatoid arthritis (RA), gout, systemic lupus erythematosus (SLE), and other inflammatory or [...]

655 1519

Open Access Original Research

Compassionate Mind Training for All: An Evaluation of a One-Day Compassionate Mind Training Workshop for Mental Health NHS Staff as Part of Compassion Focused Staff Support

Received: 13 October 2025;  Published: 13 February 2026;  doi: 10.21926/obm.icm.2601009

Abstract

It has become increasingly evident that individuals who work in the NHS can be heavily impacted by the nature of their work; for instance, PTSD, work related burnout, vicarious trauma, moral injury, anxiety, and depression. In turn, individuals who experience said psychological difficulties often require work-related mental health leave from work. This paper examines the experience of a One-day Compassionate Mind Training workshop (CMT), available for all NHS staff. This day has an emphasis on developing multidirec [...]

436 1488

Open Access Original Research

Wind Turbine Tower Structural and Cost Optimisation within Acceptable Structural Integrity

Received: 26 June 2025;  Published: 13 February 2026;  doi: 10.21926/jept.2601003

Abstract

As the demand for cleaner-greener energy surges owing to more nations adopting Net Zero Emission by 2050, wind turbine (WT) technology is increasingly poised as one of the technologies to match the demand. Capacity building in the development of cost-effective WT tower with improved reliability and safety has become critical to delivering Net Zero mandate. This research demonstrates implementation of Taguchi Design of Experiment (DoE) in conjunction with Signal-to-noise ratio (S/N) to optimise both structural desig [...]

444 1488

Open Access Case Report

Diagnostic Challenges of Rothmund-Thomson Syndrome in Infancy: A Case Report from a Resource-Limited Setting

Received: 26 October 2025;  Published: 11 December 2025;  doi: 10.21926/obm.genet.2504320

Abstract

Rothmund-Thomson syndrome (RTS) is a rare autosomal recessive disorder characterized by early-onset poikiloderma and multisystem abnormalities. Diagnosis is often confirmed through genetic testing, but in many resource-limited settings, molecular studies are unavailable, necessitating reliance on clinical and histopathological evaluation. We report a 1-year-old boy referred for assessment of progressive pigmented skin lesions. The patient was referred by a pediatrician with febrile neutropenia, bicytopenia suspicio [...]

522 1487

Open Access Original Research

Psychological Flexibility in Borderline Personality Disorder: A Comparative Study with Healthy Controls

Received: 09 March 2025;  Published: 31 December 2025;  doi: 10.21926/obm.neurobiol.2504316

Abstract

This study aimed to examine the psychological flexibility of individuals diagnosed with borderline personality disorder (BPD) compared to healthy controls. Psychological flexibility is a key construct related to mental health and adaptive functioning, and understanding its levels in BPD can provide insight into symptom severity and treatment outcomes. The study included 58 individuals diagnosed with BPD and 62 healthy volunteer controls, all meeting specific inclusion and exclusion criteria. Participants completed [...]

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