by OBM Genetics Editorial Office

Received: 07 January 2021;  Published: 07 January 2021;  doi: 10.21926/obm.genet.2101122

The editors of OBM Genetics would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2020. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers receive a voucher entitling them to a discount on their next LIDSEN publication and can download a certificate of recognition di [...]

by Carlos Armenta-Déu

Received: 20 September 2024;  Published: 20 January 2025;  doi: 10.21926/rpse.2501001

This work focuses on designing a control unit for improving Proton Exchange Membrane Fuel Cell (PEMFC) performance powering electric vehicles when operating in variable atmospheric pressure conditions, a current situation in mountainous countries with sudden changes in road altitude. The paper studies and analyzes the PEM fuel cell behavior working with hydrogen supply from a pressurized tank and oxygen input from atmospheric air supply in journeys with continuous variation of road level due to the orography. The w [...]

by OBM Neurobiology Editorial Office

Received: 04 January 2021;  Published: 05 January 2021;  doi: 10.21926/obm.neurobiol.2101081

The editors of OBM Neurobiology would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2020. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers receive a voucher entitling them to a discount on their next LIDSEN publication and can download a certificate of recognition di [...]

by Axel Becker  , Martin Helmuth  and Ben A. Chindo

Received: 19 October 2023;  Published: 05 December 2023;  doi: 10.21926/obm.neurobiol.2304200

A stroke is a cerebrovascular disease that results from a blockage in the blood supply to part of the brain or a burst blood vessel in the brain. It is the second leading cause of death worldwide, with an annual mortality rate of about 5.5 million. Antithrombotic therapies have failed to provide a cure for this debilitating cerebrovascular disorder, and hypothermia is gaining interest as a novel strategy for the management of stroke. In this study, we evaluated the effects of Ficus platyphylla-induced hypothermia o [...]

by Bruno Schubert  and David Hochmann

Received: 18 February 2024;  Published: 22 August 2024;  doi: 10.21926/rpm.2403020

This study investigates the influence of thermal environmental conditions during printing and their effects on the mechanical properties of material extrusion (MEX) 3D-printed 17-4 PH stainless steel. Various ambient temperatures and cooling behaviors were used during the printing process of the tensile specimens. Following DIN EN ISO 50125 and DIN EN ISO 6892, the study analyzes tensile strength, elongation and yield strength. The results demonstrate that the thermal environmental conditions affect both tensile an [...]

by Advances in Environmental and Engineering Research Editorial Office

Received: 06 January 2022;  Published: 06 January 2022;  doi: 10.21926/aeer.2201001

The editors of Advances in Environmental and Engineering Research would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2021. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers receive a voucher entitling them to a discount on their next LIDSEN publication and can do [...]

by Benjamin Drukarch  and Micha M.M. Wilhelmus

Received: 09 October 2024;  Published: 13 February 2025;  doi: 10.21926/obm.neurobiol.2501269

According to mainstream neuroscience, the action potential (AP) is a purely dissipative electrical phenomenon that should be modeled as such. However, also (essentially) reversible mechanical, thermal, and optical changes in the neuron have been reported to accompany the movement of the AP along the axonal surface. These are not accounted for in the prevailing (bio)-electric theory of neuronal excitability, originally introduced by Hodgkin and Huxley (HH) and mathematically formulated in their famous HH model of th [...]

by Amos O. Oyatogun  , Emmanuel Ajenifuja  , Abimbola P. Popoola  , Olawale Popoola  , Fatai O. Aramide  and Grace M. Oyatogun

Received: 28 December 2023;  Published: 01 July 2024;  doi: 10.21926/rpm.2403016

High strength and good conductivity are both critical parameters for copper-based alloys for electrical and other technological applications. This study is aimed to produce copper alloys and metal matrix composites (MMCs) with enhanced physical properties. Cu-Ti-Ni ternary alloys and MMCs samples were sintered at 600 to 700°C using spark plasma sintering (SPS), with a heating rate of 100°C/minutes, uniaxial pressure of 50 MPa, and a holding time of 10 minutes. Scanning electron microscopy (FE-SEM) was used to exami [...]

by OBM Transplantation Editorial Office

Received: 09 October 2022;  Published: 17 October 2022;  doi: 10.21926/obm.transplant.2204167

by Shih Ang Hsu

Received: 31 August 2023;  Published: 20 December 2023;  doi: 10.21926/aeer.2304054

In the realm of air-sea interaction and marine meteorology, during a tropical cyclone (TC) worldwide since 2006, the Regional and Mesoscale Meteorological Branch (RAMMB) has issued surface wind analysis. Based on this TC’s isotach (line of equal wind speed) analysis, in this paper, much more meteorological-oceanographic (met-ocean) products are developed and value-added to these isotachs. They are, for marine meteorology, overwater friction velocity, wind stress, atmospheric vorticity and the mean vertical velocity [...]

by OBM Transplantation Editorial Office

Received: 04 January 2021;  Published: 06 January 2021;  doi: 10.21926/obm.transplant.2101132

The editors of OBM Transplantation would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2020. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers receive a voucher entitling them to a discount on their next LIDSEN publication and can download a certificate of recogni [...]

by Justin Chin  , Alexandra Over  , Ana Christina Reyes  , Connie Chen  , Elise Hsu  , Christine Lomiguen  and Tipsuda Junsanto-Bahri

Received: 19 September 2022;  Published: 12 December 2022;  doi: 10.21926/obm.icm.2204053

Complementary and alternative medicine (CAM) is an important feature of patient medical history. This study sought to investigate the perceptions of medical students at Touro College of Osteopathic Medicine in Harlem, New York (TouroCOM-NY) regarding Asian-origin CAM practices. An anonymous survey was distributed to first and second year TouroCOM-NY medical students, asking about their familiarity with, and general attitude towards, five categories of Asian-origin CAM (acupuncture, reiki, tai chi, Ayurveda, and use [...]

by Munafò Jessica

Received: 16 October 2023;  Published: 20 March 2024;  doi: 10.21926/obm.icm.2401020

Compassion focused therapy concepts and techniques are explored in the context of weight management efforts within community, specialist and surgical settings. Living at higher weights within a culture that over-values life at low weights can induce feelings of shame, self-loathing and hypercriticism. This article examines points at which individuals engaging in weight management may experience heightened distress and describes some of the ways that the model has been applied with this population. An outline of the [...]

by Recent Progress in Nutrition Editorial Office

Received: 05 January 2023;  Published: 05 January 2023;  doi: 10.21926/rpn.2301001

The editors of Recent Progress in Nutrition would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2022. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers receive a voucher entitling them to a discount on their next LIDSEN publication and can download a certificate of re [...]

by Che Aishah Nazariah Ismail  , Nazlahshaniza Shafin  , Khairunnuur Fairuz Azman  , Idris Long  and Nor Syafinaz Yaakob

Received: 28 September 2024;  Published: 09 April 2025;  doi: 10.21926/obm.neurobiol.2502283

Chronic pain is a significant and global healthcare issue that hugely implies the quality of life and productivity of the affected individuals. It is challenging to treat and thus necessitates a deeper understanding of its underlying pathomechanisms to develop targeted interventions. Serotonin is one of the essential neurotransmitters involved in the propagation of pain signals through both ascending and descending pathways, acting via various receptor subtypes, including the 5-hydroxytryptamine receptor-6 (5-HT6R) [...]

by Sami Goren

Received: 02 January 2024;  Published: 01 July 2024;  doi: 10.21926/aeer.2403016

Waste production is experiencing a significant increase in correlation with the growth of the human population and industrial activities. The kind of waste that is expanding at a rapid rate is known as "e-waste," which stands for electronic waste. In the context of electronic waste, the term refers to the waste produced during the disposal of electronic devices and any other components utilized in making or operating these devices. In the same way that different types of waste occur, electronic waste pollutes the e [...]

by Recent Progress in Materials Editorial Office

Received: 11 April 2022;  Published: 14 April 2022;  doi: 10.21926/rpm.2202007

An Interview with Prof. Vincenzo M. Sglavo.

by Boram Lee  and Hyelin Jeong

Received: 13 April 2023;  Published: 07 August 2023;  doi: 10.21926/obm.neurobiol.2303177

The COVID-19 pandemic and its associated disruptions have significantly impacted university students’ lives worldwide. The COVID Stress Scale (CSS) is a 36-item self-reporting instrument designed to measure stress caused by the COVID-19 pandemic. This study purposed to examine the psychometric properties of the Korean version of the CSS for use with Korean university students. The study sample comprised 402 undergraduate students enrolled in a four-year private university in central South Korea. This cross-sectiona [...]

by Nadia A. Abdelmegeed Abdelwahed  and Muhammad Sufyan Ramish

Received: 27 October 2024;  Published: 14 February 2025;  doi: 10.21926/obm.neurobiol.2501270

This study examines the effect of e-learning crack-up perception (ECUP) and fear of academic year loss (FAYL) on psychological distress (PD). The study also explores the impact of PD on students' academic performance (AP). It uses a quantitative method based on data collected from Egyptian medical university students using convenience sampling. The study utilized 313 cases to get the final results. Using path analysis through analysis of moment structures (AMOS) software, the study confirmed a positive effect o [...]

by Yusuke Kataoka

Received: 25 October 2022;  Published: 06 April 2023;  doi: 10.21926/aeer.2302026

Understanding the urban environment and the health status of residents is necessary for appropriate administrative services and regional management. This study used indicator scores derived from the area statistics of cities in the Tokyo metropolitan area to identify factors that affect health status. Indices were classified into two groups: health-related and non-health-related. The index values of each group served as the observed variables and were statistically standardized. The relationship between the two gro [...]

by John A. T. Bye

Received: 13 November 2022;  Published: 05 February 2023;  doi: 10.21926/aeer.2301018

This paper presents a model for the similarity structure of the velocity profiles in air and water in the wave boundary layer, which provides predictions in terms of two parameters, F and R, of all its important properties, including the Charnock parameter, the surface drift velocity and the condition for the cancellation of the surface Stokes velocity by the surface current. The parameter, F, arises from the fetch variability of the wave field, and the parameter, R, arises from the duration variability of the wave [...]

by Gilles R. G. Monif

Received: 06 January 2019;  Published: 04 June 2019;  doi: 10.21926/obm.hg.1902021

Using the therapeutic intervention points identified by the Hruska Postulate, the probability of curing Crohn’s disease through destroying the anti-MAP template is discussed.

by Vladimir N. Gorchakov  , Kirill M. Nicolaychuk  , Olga V. Gorchakova  , Georgi A. Demchenko  and Bayan A. Nurmakhanova

Received: 09 July 2023;  Published: 01 November 2023;  doi: 10.21926/obm.geriatr.2304257

Lymph nodes are prioritized in protecting and ensuring endoecological safety at different periods of life, especially in retirement age. It destabilizes the structure and function of the lymphatic system and organs when aging increases the risk of comorbid conditions. This is a sign of age-related pathology. Improving lymph node function is an essential task in integrating gerontology and lymphology. The solution to this problem is possible with the help of a phytotherapeutic agent, which involves the evaluation of [...]

by Luis A. Méndez-Rosado  , Alicia Vaglio  , Roberto Lardoeyt-Ferrer  , Albertino Candimba-Sebastiao  , Judith Pupo-Balboa  , Ivan Y. Iourov  and Alejandro Esperon

Received: 19 March 2024;  Published: 24 June 2024;  doi: 10.21926/obm.genet.2402247

Silver-Rusell syndrome is a rare genetic disease. There is evidence that the genetic causes of the disorder are heterogeneous, with predominant alterations in the imprinted regions of chromosomes 11 and 7, in addition to other genomic alterations, such as chromosomal structural aberrations, single nucleotide polymorphisms, copy number variations, and small insertions and deletions. The most prevalent clinical manifestations include prenatal and postnatal growth retardation, dysmorphic features, and feeding difficul [...]

by Mohammad-Reza Ghasemi  , Maryam Mirahmadi  , Hadi Bayat  , Mohammad Miryounesi  , Reza Mirfakhraie  , Shadab Salehpour  , Raheleh Tangestani  , Faezeh Sherafat  , Hasan Roudgari  and Milad Gholami

Received: 16 January 2025;  Published: 21 May 2025;  doi: 10.21926/obm.genet.2502294

Kabuki Syndrome (KS) is a rare, multisystem congenital disorder with five foremost clinical manifestations encompassing dysmorphic facial characteristics, postnatal growth constraint, craniofacial/skeletal anomalies, mild to moderate intellectual disability, and dermatoglyphic abnormalities. We analyzed two unrelated Iranian patients suspected of having KS using whole-exome sequencing. An in silico analysis was performed to evaluate the potential effects of the discovered variants on the structure and function of t [...]

by Koji Takahashi  , Tatsuo Kanda  , Yuki Haga  , Reina Sasaki  , Masato Nakamura  , Shuang Wu  , Shin Yasui  , Hidehiro Kamezaki  and Osamu Yokosuka

Received: 23 June 2017;  Published: 27 July 2017;  doi: 10.21926/obm.hg.1703004

(1) Background: Infection with hepatitis B virus (HBV) infection during pregnancy occasionally raises concerns, including acute exacerbation and the potential for mother-to-child transmission. (2) Case Report: Here, we present a case of a female patient with a chronic HBV infection who was treated with tenofovir disoproxil fumarate (TDF) and had a normal pregnancy and delivery. Furthermore, the use of TDF, HBV vaccination and passive immunization of her child with hyperimmune hepatitis B immunoglobulin successfully [...]

by Mega Obukohwo Oyovwi  , Victor Oghenekparobo Emojevwe  , Benneth Ben-Azu  and Ejayeta Jeroh

Received: 31 March 2025;  Published: 09 July 2025;  doi: 10.21926/obm.neurobiol.2503291

Traumatic brain injury (TBI) is a significant public health concern, leading to substantial morbidity and mortality. While the primary injury is mechanical, the subsequent neuroinflammatory cascade plays a critical role in secondary injury and long-term neurological deficits. Astrocytes, the most abundant glial cells in the brain, play a key role in this cascade, interacting with neurons in a complex interplay that can both protect and exacerbate neuronal damage. This paper aims to provide a comprehensive overview [...]

by Juveriya Israr  and Ajay Kumar

Received: 03 August 2024;  Published: 24 February 2025;  doi: 10.21926/obm.transplant.2501236

COVID-19 has presented considerable health hazards, particularly for immunocompromised persons, such as kidney transplant recipients. This population experiences increased susceptibility due to the immunosuppressive treatments necessary to avert organ rejection, potentially resulting in a diminished immune response to immunizations. The implementation of COVID-19 vaccinations has been essential in alleviating these dangers. Studies demonstrate differing levels of vaccine efficacy among kidney transplant recipients, [...]

by Joseph S. D'Arrigo

Received: 26 June 2022;  Published: 19 December 2022;  doi: 10.21926/obm.icm.2204054

The cardiovascular risk factors for dementia trigger widespread inflammation and oxidative stress. These two interacting processes lead to neurodegeneration, gradual cognitive/memory decline, and eventually (late-onset) dementia. In addition, there is supporting evidence pointing to elevated pulse pressure as a clear risk factor for cognitive decline. Accordingly, an effective therapeutic strategy to delay dementia could be based upon nanotargeting bioactive molecules, using lipid nanocarriers, toward cell-surface [...]

by Carlos Armenta-Déu  and Ángela Trujillo

Received: 10 October 2024;  Published: 07 March 2025;  doi: 10.21926/jept.2501005

The growing demand for energy and the need to reduce dependence on non-renewable sources have driven the research and application of sustainable technologies. In this context, an integrated solution that combines distributed energy generation from renewable sources, such as wind and hydro, with efficient management of household energy consumption is proposed. This study focuses on the hybrid renewable energy system simulation analysis designed to meet the demand of an off-grid household in a self-consumption mode. [...]

by Anna Passaro  , Antonio Zullo  , Mariacarla Di Gioia  , Mirella Dragone  , Khalida Akbar  and Fabrizio Stasolla

Received: 30 May 2024;  Published: 15 August 2024;  doi: 10.21926/obm.neurobiol.2403240

The management and treatment of challenging behaviors in children diagnosed with Autism Spectrum Disorder (ASD) is a priority for caregivers, educators, and healthcare professionals. This selective review examined how different technologies were used to help manage challenging behaviors in children with autism, describing each technology's strengths, weaknesses, and applications. This paper aimed to provide accessible choices for caregivers, educators, and healthcare professionals, enabling them to make well-inform [...]

by Ibram Ganesh

Received: 31 July 2025;  Published: 17 September 2025;  doi: 10.21926/rpse.2503013

The United Nations Organization (UNO) in the year 2015 formulated seventeen sustainable development goals (UNO’s 17 SDGs) to be achieved by the end of the year 2030. The so far achieved progress indicates that none of these UNO’s 17 SDGs can be achieved before the deadline. In fact, all these goals can be achieved by developing suitable technologies to fully capture and utilize all the renewable energy resources available on earth to meet all the energy needs of society without any backup from fossil fu [...]

by Alastair C. Gray  , Parker Pracjek  , Christine D. Luketic  and Denise Straiges

Received: 03 September 2024;  Published: 09 December 2024;  doi: 10.21926/obm.icm.2404069

Research into the uptake profile and usage of Homeopathy has hitherto tended to be buried amongst complementary medicine research. Despite high levels of uptake of homeopathy, and robust numbers of over-the-counter sales of homeopathic products the current evidence evaluating the uptake of homeopathy remains limited on several fronts. The aim of this study is to explore the basic demographic features and characteristics of users of homeopathy services. The setting is a student teaching tele-health facility based in [...]

by Yohanes Ridora  , Niken Trisnowati  and Retno Danarti

Received: 05 February 2024;  Published: 19 April 2024;  doi: 10.21926/obm.genet.2402229

Xeroderma pigmentosum (XP) is a rare genodermatosis characterized by increased sensitivity to ultraviolet radiation, leading to severe skin manifestations and a higher risk of early-onset malignancies. Previous studies from temperate climate countries with sound economic levels showed adequate photoprotection compliance among pediatric XP patients. However, no studies have assessed photoprotection compliance among children with XP living in tropical and low-economic settings. This article reports a low photoprotect [...]

by Olubunmi Yemisi Fashoto  , Maureen Nokuthula Sibiya  and Olanrewaju Oladimeji

Received: 09 July 2024;  Published: 08 November 2024;  doi: 10.21926/obm.neurobiol.2404253

The availability and utilization of digital technologies can leverage the challenges of the sharp-depleting workforce due to the consistent migration of healthcare professionals (HCPs), the alarming ratio of the number of patients to HCPs, discretional use of digital technologies among HCPs in providing effective therapeutic interventions and mental healthcare services. This study aimed to develop an operational model that integrates digital technologies in mental healthcare service delivery for public facilities i [...]

by Irina V. Tarasova  and Olga A. Trubnikova

Received: 02 November 2023;  Published: 19 March 2024;  doi: 10.21926/obm.neurobiol.2401215

Postoperative cognitive dysfunction (POCD) has been observed as a complication after cardiac surgery consistently. The ineffectiveness of current treatments for POCD is causing a search for non-invasive alternatives. The present review aims to consolidate the current understanding of how VR methods effectively facilitate the recovery of cognitive functioning in cardiac surgery patients. To obtain information about the effects of VR technology on cognitive functions, we investigated the PubMed, Scopus, and Web of Sc [...]

by Dorcas N. Magai  and Hans M. Koot

Received: 29 May 2024;  Published: 29 November 2024;  doi: 10.21926/obm.icm.2404068

This cross-sectional study addressed the association between parental and family characteristics as risk factors for emotional and behavioral problems (EBP) and quality of life (QoL) and the potential moderation of these associations by adolescents' characteristics. A total of 533 households from Central Kenya with adolescents between 12 to 18 years (median age 15 years) and their mothers (or female caregivers) were included in this study. Adolescents and their mothers completed questionnaires on parent and family [...]

by Amale Laouar

Received: 22 July 2018;  Published: 09 September 2018;  doi: 10.21926/obm.hg.1803010

Gut microbes and pathophysiology of sepsis: Spillage of gut microbial products, rather than systemic dissemination of gut microbes, is the potential initiator of septic morbidity

by Jacqueline B. Sperling  , Abigail M. Stark  and Julianne G. Wilner

Received: 27 January 2025;  Published: 26 June 2025;  doi: 10.21926/obm.icm.2502028

School avoidance is associated with a range of negative outcomes and has been increasing in youth in the past several decades. This study examined the efficacy of an intensive outpatient CBT program, for youth (N = 137, ages 8-19) with anxiety disorders or obsessive-compulsive disorder (OCD) and compared both baseline symptoms and outcomes for youth with school avoidance compared to those without. At admission, results indicated that parents of children with school avoidance reported higher levels of family accommo [...]

by Marcel Tomaszewski  and Philip Wong

Received: 22 August 2018;  Published: 03 January 2019;  doi: 10.21926/obm.hg.1901013

There is evidence to suggest that older livers regenerate less well and display cellular senescence. Additionally, elderly patients with certain liver diseases have a less favourable course. Chronic liver disease, amongst the elderly, has a significant negative effect upon quality of life and functional independence. Frailty, commonly encountered in geriatric patients, remains a significant negative predictor of physical, psychological, functional and survival outcomes in chronic liver disease. Despite advances in [...]

by Rolf Teschke  and Axel Eickhoff

Received: 08 January 2025;  Published: 14 February 2025;  doi: 10.21926/obm.transplant.2501234

Liver transplantation (LT) can be the only option for patients with acute liver failure (ALF) where medical approaches are ineffective. Causes of ALF are multiple and commonly easily detectable, but uncertainty remained on the role of drug-induced liver injury (DILI) within the published ALF cohorts. Therefore, an analysis was undertaken to clarify which drugs may have caused the DILI and how the diagnosis of the liver injury was established. Using the PubMed database and Google Science, the search term of acute li [...]

by OBM Hepatology and Gastroenterology

Received: 04 January 2021;  Published: 05 January 2021;  doi: 10.21926/obm.hg.2101054

The editors of OBM Hepatology and Gastroenterology would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2020. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers receive a voucher entitling them to a discount on their next LIDSEN publication and can download a certificat [...]

by Zongqi Guo  and Wenxu Wei

Received: 12 January 2024;  Published: 12 April 2024;  doi: 10.21926/rpm.2402010

Ceramic bonds are conventionally formed during the burning of refractory bricks and by using pre-fabricated blocks or monolithic lining, which is characterized as the coalescence of the particles by liquid sintering. However, the whisker bond was discovered with the outstanding performance of unburnt periclase–spinel–Al bricks while substituting magnesia–chrome bricks in the chromium-free campaign of refractory lining of RH degassers. Thanks to the prominent effect of the whisker bond, such a refr [...]

by Mojtaba Ehsanifar  , Akram Gholami  and Joseph P Reiss

Received: 13 June 2025;  Published: 21 October 2025;  doi: 10.21926/obm.neurobiol.2504305

Evidence from recent studies has suggested a significant association between mycotoxin exposure and neuroinflammation, potentially contributing to the onset of neurocognitive disorders during key developmental stages of the brain. Various research highlights how exposure to these toxins is correlated with a decline in cognitive performance, reduced motor skills, and behavioral issues. Mycotoxins are also implicated in interfering with neuronal signaling pathways and the functioning of neurotransmitters, which may l [...]

by Jose Benavides  , Pushpesh Sharma  , Ahmed Al Saedi  and Shah Kabir

Received: 20 November 2023;  Published: 21 February 2024;  doi: 10.21926/jept.2401007

This article outlines an innovative approach to explore thermal energy extraction for power generation or industrial hot water applications. Unlike traditional steady-state models, this approach embraces time-variant scenarios, explicitly incorporating a cyclical fluid circulation strategy to maintain a stable surface fluid temperature or power output. By introducing an increasing and decreasing stepwise rate sequence and an intermittent circulation strategy, the method aims to optimize efficiency in response to va [...]

by José A. Cedeño-Escudero  , Luis A. Sotillo-Bent  , Carolina Vega- Cuellar  , Rolando González-Angulo  , Evelyn Medina-Batista  , José Sotillo-Lindo  and Luis A. Méndez-Rosado

Received: 13 August 2024;  Published: 12 October 2024;  doi: 10.21926/obm.genet.2404266

Hypertrophic cardiomyopathy (HCM) is the most common inherited cardiomyopathy, affecting approximately 1 in 500 people. It is the most common genetic cardiomyopathy inherited as a Mendelian trait in approximately 50% of patients, mainly due to pathogenic variants in genes encoding sarcomeric proteins. Mutations in the sarcomeric protein filamin C (FLNC) gene, with a cytogenetic localization on 7q32.1, have been linked to hypertrophic cardiomyopathy, as they have been determined to increase the risk of ventricular a [...]

by Fatimazahra Smaili  , Khawla Zerrouki  , Fatima Ezzahra Aouni  , Ayad Ghanam  , Maria Rkain  , Abdeladim Babakhouya  and Mariam Tajir

Received: 04 October 2024;  Published: 04 February 2025;  doi: 10.21926/obm.genet.2501283

Dystrophinopathies are genetic muscular disorders with recessive inheritance linked to the X chromosome due to mutations in the dystrophin gene, the DMD gene located in Xp21. The best-known forms are Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD). Our study aims to determine the molecular profile and genotype/phenotype correlations of dystrophinopathies in the eastern region of Morocco. We report patients referred for 4 years (2020-2023) to the Medical Genetics Laboratory of the Mohammed VI U [...]

by Varrassi Giustino

Received: 01 February 2024;  Published: 02 February 2024;  doi: 10.21926/obm.neurobiol.2401210

Neurobiology is an expansive field of studies encompassing the nervous system's anatomical and physiological aspects [1]. This complex framework's deep study and understanding have facilitated a more intricate comprehension of the interconnections among various nervous system components implicated in pain perception, transmission, modulation, and adaptation.

by Abubakar Siddiq Salihu  , Wan Mohd Nuzul Hakimi Wan Salleh  , Nurunajah Ab Ghani  , Mohd Hafiz Arzmi  , Bunleu Sungthong  and Ravikumar Kapavarapu

Received: 05 March 2025;  Published: 27 April 2025;  doi: 10.21926/obm.neurobiol.2502286

The Myristicaceae family, particularly the Knema genus, is renowned for its diverse bioactive compounds, including lignans, flavonoids, and phenolics. This study explores the phytochemical profile of Knema hookeriana Warb. leaves and evaluates their potential as acetylcholinesterase (AChE) inhibitors. Phytochemical extraction was performed using a cold maceration method with a polarity-gradient solvent system (hexane, ethyl acetate, and methanol). The isolated compounds were purified through chromatographic techniq [...]

by Nadia A. Abdelmegeed Abdelwahed  and Muhammad Sufyan Ramish

Received: 12 May 2024;  Published: 19 August 2024;  doi: 10.21926/obm.neurobiol.2403242

In the present era of digitalization, technology plays a prominent role in relaxation and brain development (BD), specifically for university students. The present study explores the impact of technology use and digital characteristics (DC) in developing students' BD. We applied the quantitative methods; the study collected 328 samples from Egypt's different public sector universities through a questionnaire. Using path analysis through analysis of moment structures (AMOS), the results demonstrate a positive effect [...]