by OBM Genetics Editorial Office

Received: 13 December 2022;  Published: 14 December 2022;  doi: 10.21926/obm.genet.2204174

An Interview with Dr. Masahiro Sato

by Claire Robson  , Jen Marchbank  and Gloria Gutman

Received: 27 November 2023;  Published: 31 January 2024;  doi: 10.21926/obm.geriatr.2401267

Though research suggests that older adults belonging to gender and sexual minorities (GSM) are at greater risk of abuse and neglect, more needs to be done to investigate this situation, provide solid data, offer support to survivors and better inform those providing services. This article reports on a participatory action research project in which nine older adults with lived experience of abuse were interviewed, as were the seniors’ programmer from our community partner organization and a trauma counsellor who sup [...]

by Tatsuya Kin  , Hirofumi Noguchi  and Atsushi Kawaguchi

Received: 15 February 2024;  Published: 03 June 2024;  doi: 10.21926/obm.transplant.2402216

Using donation after circulatory determination of death (DCD) donors has been shown to be a potential means of increasing the number of donors for organ transplantation. The purpose of this study was to examine the published practice of DCD in Japan to properly define their practice as controlled or uncontrolled. Through the Web of Science database, we systematically searched articles describing uncontrolled DCD, controlled DCD or Maastricht classification. A total of 12 articles (ten articles related to kidney, on [...]

by Subhranshu Sekhar Kar  , Rajani Dube  , Biji Thomas George  and Malay Jhancy

Received: 07 April 2024;  Published: 20 December 2024;  doi: 10.21926/obm.genet.2404276

There is a high prevalence of genetic abnormalities that significantly contribute to overall morbidity and mortality in neonates. Since early diagnosis is crucial for the optimal administration of conventional and customized medications, neonatal acute care has the most significant potential to benefit from genomic medicine. Genome sequencing has been demonstrated to have diagnostic, therapeutic and informational value in many investigations. With underlying genetic disorders, genome sequencing has the power to cha [...]

by Nadia A. Abdelmegeed Abdelwahed

Received: 08 January 2024;  Published: 06 May 2024;  doi: 10.21926/obm.neurobiol.2402222

In the present era, a healthy life is a challenge for everyone. Therefore, diverting individuals' minds towards physical activity and exercise is necessary for the day. This paper proposes to inspect the impact of physical activity on the development of intention to exercise (ITE) among entrepreneurs. The quantitative study collected data from 383 Egyptian entrepreneurs through a survey questionnaire. Most respondents were males (n = 257 or 67.10%) against females (n = 126 or 32.90%). The range of age of the respon [...]

by Jianquan Xu  , Jinwen Liu  , Wen Lei  , Zhong Lu  and Long Ying

Received: 01 September 2024;  Published: 10 January 2025;  doi: 10.21926/aeer.2501005

To study the environmental impact of automobile components, life cycle assessment (LCA) is adopted to study the environmental impact of instrument cross beams made of steel and magnesium alloy crossbeams. Comparative environmental impact analyses of both instrument crossbeams are conducted through parametric analysis, scenario analysis, sensitivity analysis, and future forecasting in GaBi10. The results show that global warming potential (GWP), acidification potential (AP), eutrophication potential (EP), ozone depl [...]

by Gabriel de Souza Vieira Bié  , Zilda de Castro Silveira  , Rafael Vidal Aroca  and Marcia Cristina Branciforti

Received: 07 February 2025;  Published: 28 May 2025;  doi: 10.21926/rpm.2502010

Tissue engineering is a technique for regenerating living tissue using portions of the patient's tissue, which are dissociated into cells and cultured on biological or synthetic supports before being transferred to the patient. In this context, the present study seeks to develop implant models (scaffolds) for replacing trabecular bone tissue, with requirements such as porosity and interconnected pores. All design development was aimed at the manufacturing of scaffolds using the material extrusion additive manufactu [...]

by Habibur P. Rahman  , DaiRicky H Bhogal  and Patricia F. Lalor

Received: 05 February 2018;  Published: 16 May 2018;  doi: 10.21926/obm.hg.1802007

Background & Aims. Acute kidney injury (AKI) is a serious complication of liver surgery and associated with significant morbidity and mortality. The incidence of AKI following hepatic surgery can be as high as 94%, with highest rates seen following orthotopic liver transplantation, particularly when extended criteria grafts are used. Strategies to identify patients at risk of AKI may enable early interventions to prevent or minimise AKI. Methods. A systematic review was conducted using PubMed, Medline, Cochrane and [...]

by E. García – Quismondo  and A. Guillermo Bracamonte

Received: 14 October 2023;  Published: 31 January 2024;  doi: 10.21926/rpm.2401003

This communication was brief to show how high conjugated carbon-based structures and carbon allotropes could participate as electron shuttles, semiconductors, quantum emitters, and Optoelectronic processors within confined nanostructured organized systems. In particular, it was focused on nanoassemblies such as vesicles, micelles, and lipidic nanoparticles and incorporated insights from other types of nanomaterials that could afford to develop new organized systems. In these cases, the term organized system was use [...]

by Daming Zhang  and Xiuhui Tang

Received: 01 September 2023;  Published: 29 November 2023;  doi: 10.21926/jept.2304039

Large-scale autonomous microgrids have potential application values as they can increase renewable energy penetration level without compromising the stability of the existing large power systems. Before their widespread implementation, critical issues like stability analysis etc need to be solved. This paper analyses the stability in an autonomous microgrid operated at constant frequency with the consideration of reactive power balance. Difference equations of reactive power for the grid-forming generator are const [...]

by Giulio E. Lancioni  , Gloria Alberti  , Chiara Filippini  , Alessandra Fiore  , Clarissa Simonetti  , Nirbhay N. Singh  , Mark F. O'Reilly  and Jeff Sigafoos

Received: 09 October 2023;  Published: 02 January 2024;  doi: 10.21926/obm.neurobiol.2401203

This study adapted a new interactive technology system to help six participants with intellectual disability and visual and motor impairments to exercise relevant physical responses as part of an occupational task. The task was to place objects into different containers from a sitting position. The responses, which changed across sessions, consisted of the participants (a) stretching the left arm and shoulder to place objects in a container located to their left, (b) stretching the right arm and shoulder to place o [...]

by Toku Takahashi

Received: 28 August 2023;  Published: 27 February 2024;  doi: 10.21926/obm.icm.2401016

In modern society, depression is one of the most common mental disorders. It is generally thought that depression is due to the disorders of neuronal circuits and chemical balance in the brain. Patients with depression often receive treatment with selective serotonin reuptake inhibitors (SSRIs). However, recent studies suggest that the magnitude of benefit of pharmacological treatment is quite limited for these patients. Although recent studies propose acupuncture as a non-pharmacological approach to managing depre [...]

by Despina Vamvuka  and Christia Loulashi

Received: 24 May 2022;  Published: 29 September 2022;  doi: 10.21926/cr.2203031

The present study investigated the co-gasification of two different lignites blended with the forest residue collected from the land restoration activity sites of open-pit mines located in the region of the Ptolemais basin in North Greece performed under the carbon dioxide stream. All samples were devolatilized in a fixed bed unit prior to the gasification evaluations. The gasification evaluations were performed using a thermal analysis system (TG/DTG) operated at temperatures of up to 1000 °C. The reactivity, [...]

by Somaye-Sadat Heidari  , Nooshin Dalili  , Shiva Samavat  , Shiva Kalantari  , Leonard Foster  , Kyung-Mee Moon  and Mohsen Nafar

Received: 12 July 2023;  Published: 25 September 2023;  doi: 10.21926/obm.transplant.2303196

Acute antibody-mediated rejection (AMR) is a severe complication affecting kidney allografts' long-term survival. Timely detection and appropriate treatment of AMR are crucial for improving graft outcomes. This study aimed to discover non-invasive urinary biomarkers that can predict the response to therapy in patients with AMR. Materials and Methods: In this case-control study, urine samples from 21 biopsy-proven AMR patients underwent proteomics using label-free quantification. The patients were divided into two g [...]

by Biagio Pinchera  , Rosa Carrano  , Emilia Trucillo  , Alessia D'Agostino  , Alessia Sardanelli  , Simona Mercinelli  , Fabrizio Salemi  , Amerigo Piccione  , Elisa Schettino  , Paolo Romano  , Gianluca Rompianesi  , Roberto Ivan Troisi  and Ivan Gentile

Received: 19 July 2023;  Published: 01 November 2023;  doi: 10.21926/obm.transplant.2304200

The rising prevalence of MDR pathogens has a significant impact on the recipients' outcome, as this increases the risk of graft complications and makes the management of the peri-transplant phase more difficult. Among the different MDR germs, Methicillin-resistant Staphylococcus aureus (MRSA) represents one of the most frequently isolated pathogens. We report for the first time the off-label use of Ceftaroline in six kidney transplant recipients with donor peritransplantation MRSA bacteremia at the Division of Kidn [...]

by Justin Cole  , Eugene Golts  , Michael Bernales  , Dina Shirazi  , Deepa Kurup  , Sarah Golts  , Gordon Yung  , Aarya Kafi  , Christine M. Lin  , Travis Pollema  and Kamyar Afshar

Received: 19 October 2023;  Published: 08 May 2024;  doi: 10.21926/obm.transplant.2402214

Despite the concerted efforts by lung transplant recipients (LTR) and their medical teams, hospital readmissions are common in the first year following transplantation. Reasons for unplanned readmissions include allograft rejection, infections, and respiratory failure before the SARS-COV-2 pandemic. Clinical predictors of readmissions have changed over time with the higher risk factors of acceptable criteria for recipients and donors. We aimed to assess more recent readmission rates based on group classifications t [...]

by Van Anh Vu  , Joelle Nelson  , Helen Sweiss  , Reed Hall  , Holly Keyt  and Elisabeth Kincaide

Received: 29 January 2024;  Published: 03 July 2024;  doi: 10.21926/obm.transplant.2403220

Secondary hypogammaglobulinemia (HGG) from immunosuppression therapy in lung transplant recipients has been associated with increased mortality, morbidity and higher risk of infection. Intravenous immunoglobulin (IVIG) for the treatment of HGG post-lung transplant is not well studied with conflicting evidence regarding efficacy. This single-center, retrospective cohort study analyzed adult lung transplant recipients with HGG receiving ≥1 dose of IVIG 0.3-0.5 g/kg. Resolution of HGG (IgG > 600 mg/dL wi [...]

by Dennis Rosenberg  and Sharon Shiovitz-Ezra

Received: 13 March 2023;  Published: 11 July 2023;  doi: 10.21926/obm.geriatr.2303242

The current study aimed to examine the link between cross-temporal patterns of care provision and loneliness in older adults. Social capital and caregiver stress perspectives served as a theoretical framework for the study. The data were obtained from the two COVID-19 waves of the Survey of Health, Ageing, and Retirement in Europe (SHARE) conducted in 2020 and 2021. The data were analyzed using logistic regression models. The analytical sample consisted of 48,722 older adults residing in Europe and Israel. The anal [...]

by Dafni Foti  , Costas Passialis  , Elias Voulgaridis  and Stergios Adamopoulos

Received: 23 August 2022;  Published: 28 October 2022;  doi: 10.21926/rpm.2204022

Cellulosic fibrous mats were impregnated with various water-repellent formulations based on reclaimed polystyrene (5, 10, 15, and 20%), alkyd resin (5%), gum rosin (5%), and paraffin wax (0.5%). The mats were tested for their bursting strength and resistance to bending. They were also subjected to the ring crush test and short-span compression test. By increasing the concentration of total solid ingredients (5, 10, 15, 20, and 25.5%), the retention and grammage of the mats were increased, and all strength propertie [...]

by Advances in Environmental and Engineering Research Editorial Office

Received: 04 January 2021;  Published: 06 January 2021;  doi: 10.21926/aeer.2101001

The editors of Advances in Environmental and Engineering Research would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2020. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers receive a voucher entitling them to a discount on their next LIDSEN publication and can do [...]

by Carolina Ramírez  , Elizabeth González  and Fernando Tomasina

Received: 23 September 2024;  Published: 20 May 2025;  doi: 10.21926/aeer.2502023

Healthcare Waste (HCW) management is a pressing challenge in Latin America, where insufficient regulatory enforcement, poor segregation practices, and the lack of accurate generation data hinder sustainable waste management. This study presents a methodological proposal for the internal management of HCWs in Healthcare Centers (HCCs) in Uruguay, based on Decree 586/009 and developed through a situational diagnosis conducted at the Hospital de Clínicas "Dr. Manuel Quintela." The diagnosis involved the qualitative an [...]

by Ivan Stoyanov  , Penka Vasileva  , Teodora Staykova  , Teodora Popova  and Evgeniya N. Ivanova

Received: 22 June 2023;  Published: 14 December 2023;  doi: 10.21926/obm.genet.2304208

Data from the present study indicate that the neonicotinoid insecticides Nuprid 200 SL (with the active substance imidacloprid) and Calypso 480 SC (with the active substance thiacloprid) reduce the mitotic activity by inhibiting cell division and increasing chromosomal aberrations in the cells of the root apical meristem of Allium cepa L. The tested solutions of pesticides cause a wide range of anomalies associated with disorders in forming the cell's division apparatus and the integrity of chromosomes. The compara [...]

by Somayeh Alimoradi Askari  , Mehdi Nasr Esfahani  , Kowsar Shirazi  , Arman Nasr Esfahani  , Hossein Zeinalzadeh-Tabrizi  and Mojtaba Mohammadi

Received: 23 January 2024;  Published: 28 April 2024;  doi: 10.21926/obm.genet.2402231

Garlic (Allium sativum), cultivated worldwide for its medicinal and nutritional value, faces challenges due to diseases caused by various pathogens. In this study, eleven garlic genotypes from Iran and one from China were selected and sown under natural infection rendered by the rust fungus (Puccinia alli) over two consecutive years. Subsequently, disease distribution and severity, percentage of infection and susceptibility of different garlic genotypes to rust disease were investigated. The results showed that gen [...]

by Michael A. Franklin

Received: 27 March 2023;  Published: 25 October 2023;  doi: 10.21926/obm.icm.2304045

Art therapy, imaginal mindfulness, yoga, and meditation were personal and collegial necessities for surviving the emotional fallout of isolation during the Covid-19 pandemic. Combining these practices offered us credible resources for enhancing our social, cultural, and spiritual wellness when faced with the loneliness of lockdown living. This article applies an autoethnographic lens highlighting the value of these contemplative tools for managing pandemic related distress within myself and my professional peer gro [...]

by Colin Armstrong

Received: 14 October 2021;  Published: 15 October 2021;  doi: 10.21926/obm.icm.2104035

CorrectionCorrection: Armstrong C. Unity, Continuity, Structure, and Function. The Ongoing Search for a Deeper Understanding of the Many Roles Attributed to Fascia in the Living Human Body - An Osteopathic Perspective. OBM Integrative and Complementary Medicine 2021; 6: 16Colin Armstrong *Osteopathic Centre, 1732 Voie Aurelienne, 13450 Grans, France; E-Mail: arm.colin@gmail.com*Correspondence: Colin Armstrong; E-Mail: arm.colin@gmail.comAcademic Editor: Nancy Nies Byl Special Issue: The Importance of the Fascia for [...]

by Alfonso H. Santos  , Amer Belal  , Hisham Ibrahim  and Muhannad A. Leghrouz

Received: 19 August 2022;  Published: 21 February 2023;  doi: 10.21926/obm.transplant.2301175

We aimed to identify the non-renal risk factors for simultaneous liver-kidney transplantation (SLKT) vs. liver transplantation alone (LTA) in end-stage liver disease (ESLD) patients with estimated glomerular filtration rate (eGFR) <60 ml/min, not on dialysis. Using organ procurement and transplantation network data, we studied adult ESLD patients who received deceased-donor SLKT or LTA in July 2002-Mar 2016 with a 4-point modification of renal disease (MDRD) equation-estimated glomerular filtration rate (eGFR) s [...]

by Josie M Rudolphi  , Courtney Cuthbertson  , Kimberly Keller  and Rebecca Mott

Received: 26 April 2024;  Published: 28 June 2024;  doi: 10.21926/obm.icm.2402037

Agricultural producers (i.e., farmers, ranchers) and agricultural workers (i.e., hired labor, farmworkers) have worse mental health than the general population and often lack access to mental healthcare. In response, the United States Department of Agriculture’s National Institute of Food and Agriculture funded four regional Farm and Ranch Stress Assistance Networks in 2019. In the north central region, the North Central Farm and Ranch Stress Assistance Center (NCFRSAC) was created in 2020 to develop, deliver [...]

by Bojana Petrovic  , Milica Komnenic Radovanovic  , Nikolina Erceg  , Srboljub Milicevic  and Marija Dusanovic Pjevic

Received: 22 November 2023;  Published: 17 January 2024;  doi: 10.21926/obm.genet.2401211

This study evaluates how chromosomal factors affect assisted reproduction techniques (ART) challenges among infertile couples, impacting their chances of conception. Chromosomal abnormalities, a leading cause of pregnancy failure and miscarriages, were investigated in a four-year retrospective study involving 100 patients with a history of infertility and unsuccessful IVF treatment. Among these cases, nine (9%) displayed aberrant chromosomal patterns, including balanced translocations (5%), sex chromosome deletions [...]

by Recent Progress in Materials Editorial Office

Received: 29 August 2022;  Published: 30 August 2022;  doi: 10.21926/rpm.2203016

Interview An Interview with Prof. José Ignacio Álvarez GalindoRecent Progress in Materials Editorial OfficeLIDSEN Publishing Inc., 2000 Auburn Drive, One Chagrin Highlands, Suite 200, Beachwood, OH, USA; E-Mail: rpm@lidsen.comRecent Progress in Materials2022, volume 4, issue 3doi:10.21926/rpm.2203016Received: August 29, 2022Accepted: August 29, 2022Published: August 30, 2022

by Sanjay Dutta  , Jeanette E. Villanueva  , Yashutosh Joshi  , Ling Gao  , Paul Jansz  and Peter S. Macdonald

Received: 02 April 2024;  Published: 05 August 2024;  doi: 10.21926/obm.transplant.2403222

Heart transplantation remains the gold standard treatment for end-stage heart failure. With an increasing population and improving medical therapy there is an increasing number of patients who would benefit from heart transplantation but are unable to receive one due to a shortage of suitable donor organs. This ongoing need, and significant limitations with traditional cold static storage (CSS), have driven the development of machine perfusion technology that have expanded the donor pool. Machine perfusion is divid [...]

by Hannah O'Connor  , Joseph Biederman  , Maura DiSalvo  , Gagan Joshi  , Stephen V. Faraone  and Janet Wozniak

Received: 25 January 2024;  Published: 04 June 2024;  doi: 10.21926/obm.icm.2402031

The aim of this paper is to examine effects of stimulant treatment in children and adolescents with high levels of emotional dysregulation in a psychiatric outpatient clinic. Subjects were referred children and adolescents 6-17 years of age who presented to a child psychiatric outpatient clinic between September 2016-November 2021 and received a prescription for a stimulant medication. Children were stratified into those with low and high levels of emotional dysregulation as defined by an aggregate T-score of <1 [...]

by Kwami Eli Baba  , Guy Pluvinage  and Julien Capelle

Received: 06 August 2024;  Published: 31 October 2024;  doi: 10.21926/jept.2404018

Ammonia is a toxic gas and can cause tragic consequences for humans. The damage level depends on concentration and duration of exposure. The security length associated with the risk of a tank leak at the acute exposure level of 30 ppm (AEGL-1) has been computed. Two tools have been combined: the CTOA criterion and the ALOHA software. The CTOA, a measure of fracture resistance against ductile crack propagation, is implemented in Abaqus software to compute the size of a breach in a tank submitted to internal pressure [...]

by OBM Integrative and Complementary Medicine Editoria Office

Received: 05 January 2022;  Published: 06 January 2022;  doi: 10.21926/obm.icm.2201001

The editors of OBM Integrative and Complementary Medicine would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2021. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers receive a voucher entitling them to a discount on their next LIDSEN publication and can download a cer [...]

by Anna Scheyett  , Virginia Brown  and Christopher Weatherly

Received: 24 September 2024;  Published: 16 January 2025;  doi: 10.21926/obm.icm.2501005

In this conceptual paper we apply the construct of time poverty to a novel population, farmers struggling with stress and mental health challenges. Farmers have rates of suicide that can be over three times that of the general population, with depression and anxiety at double general population rates. These are linked to the multiple stressors farmers experience due to the unpredictable nature of their work, such as weather, input costs, commodity prices, and government regulations. In addition, there are multiple [...]

by Marina van Geenhuizen  and Razieh Nejabat

Received: 11 July 2022;  Published: 16 January 2023;  doi: 10.21926/aeer.2301007

This paper pictures several risk-taking strategies of young high-tech firms in bringing energy inventions to market and ways urban policy (municipalities) may provide supporting facilities and help accelerate the energy transition. Derived from a longitudinal study of 100 firms in northwest Europe, two findings contribute to practice. Firstly, a share of almost 40 percent of university spin-off firms fails in the market introduction; if the market introduction is reached, 30 percent is relatively late. This develop [...]

by Silvio Simani  , Saverio Farsoni  and Paolo Castaldi

Received: 02 February 2023;  Published: 21 March 2023;  doi: 10.21926/jept.2301011

In agreement with the Editor-in-Chief, the editorial office, and the authors, this article has been removed and marked as retracted because its content and data contained plagiarism from an unpublished study. Please refer to the Removal Statement.

by Sarah I. Willi  , Ulrike Bacher  , Marie Noelle Kronig  , Michael Daskalakis  , Lia Bally  and Thomas Pabst

Received: 29 July 2023;  Published: 04 February 2024;  doi: 10.21926/obm.transplant.2401206

Malnutrition remains a clinical challenge in AML patients undergoing autologous hematopoietic stem cell transplantation (ASCT), leading to physical deconditioning and prolonged hospitalization. Prospective data are mainly lacking to identify those patients who may particularly benefit from parenteral nutrition in this setting. This observational, non-randomized, retrospective, exploratory cohort study assessed the nutritional development in patients following high-dose chemotherapy (HDCT) with ASCT and explored the [...]

by Luis A. Méndez-Rosado  , Luis A. Sotillo-Bent  , José Sotillo-Lindo  , Anduriña Barrios-Martínez  , Dulce Hechavarria-Estenoz  , Margarita Mayeta  , Jose Hernández-Gil  , Hector Pimentel-Benitez  , Maria Elena de la Torre  , Hibo Moreno  , Pedro Díaz-Véliz  , Alicia Vaglio  , Roberto Quadrelli  , Diana Sánchez-Peñarate  , Mabel Cerrillo-Hinojosa  , Pedro Carbonell-de la Torre  , Judith Pupo-Balboa  , Michel Soriano-Torres  , Marilyn del Sol  , Arlay Castelvi  , Enny Morales  , Damarys García  , Rocío Serrano-Hidalgo  , Catalina Obando  , Liz Pardo  , Laritza del Toro  , Miladys Martinez  , Conrado Uria-Gómez  , Maria G Arteaga Ontiveros  , Mayte Castro  , Odalys Rabelo  , Sahily Miñoso  , Deysi Licourt  , Irenia Blanco  , Roberto Lardoeyt-Ferrer  , Nereida Gonzalez  and Olga Quiñones-Masa

Received: 24 November 2024;  Published: 10 June 2025;  doi: 10.21926/obm.genet.2502296

Generally, in reciprocal translocations there are no gains or losses of genetic material. From the clinical point of view, its primary importance lies in the fact that it can generate errors due to incorrect chromosome segregation during meiosis in carriers. On the other hand, other mutations are less frequent in the genome, specifically in the DNA breakpoints implied in these translocations. In Latin America there are no large-scale reports about this topic. To contribute to the study of reciprocal translocations [...]

by Joana Neto  and Félix Neto

Received: 08 February 2024;  Published: 12 April 2024;  doi: 10.21926/obm.neurobiol.2402217

Compassionate love (CL) is a recent subject of close relationships. CL is focused on enlarging beneficence to another. The present study approaches the test of the psychometric characteristics of the shortened form of the Compassionate Love Scale for a partner (CLS-P-SF) for Brazilian college students and its relationships with background and well-being variables. The sample included 217 young adults, 46.1% women and 53.9% men. Confirmatory factor analysis revealed that the single latent factor of the CLS-P-SF is g [...]

by Arbnora Batalli-Kepuska  , Lidvana Spahiu  , Emir Behluli  and Gazmend Temaj

Received: 08 February 2024;  Published: 19 July 2024;  doi: 10.21926/obm.genet.2403253

Several therapeutic methods are used to cure acute lymphoblastic leukemia (ALL). Relapsed/refractory B-cell ALL (R/R B-ALL) remains the primary cause of death worldwide due to the limitation of cure. Blinatumomab is a bispecific T-cell engaging antibody used to treat R/R B-ALL. The use of blinatumomab for treating R/R B-ALL has shown to be very efficient, especially as a bridge tool to hematopoietic stem cell transplantation (HSCT). The response to blinatumomab treatment ranged from 69% after two cycles in phase II [...]

by Giuseppe Merra

Received: 03 July 2024;  Published: 10 July 2024;  doi: 10.21926/obm.genet.2403251

by Lamiae Afif  , Zhour El Amrani  , Aziza Sbiti  , Ilham Ratbi  , Imane Cherkaoui Jaouad  , Youssef El Kadiri  , Thomas Liehr  , Abdelaziz Sefiani  and Abdelhafid Natiq

Received: 02 April 2024;  Published: 30 August 2024;  doi: 10.21926/obm.genet.2403259

6q22.31q27 duplication and Xq28 deletion lead to two specific different rare chromosomal disorders. Partial trisomy 6q22.31q27 is a recognizable syndrome with a distinctive phenotype, and the most common finding in girls with Xqter deletions has been premature ovarian failure (POF) and secondary amenorrhea. To our knowledge, neither abnormality in one patient has yet been reported. A 10-year-old girl with de novo 6q22.31q27 duplication and Xq28 deletion was diagnosed by chromosomal microarray and confirmed by fluor [...]

by Candice Fischer  and Carolina Eugenia Cáceres Videla

Received: 21 March 2024;  Published: 12 August 2024;  doi: 10.21926/obm.icm.2403046

A growing body of evidence has highlighted the limitations of relying solely on positivist research when summarizing SP/SR results since it might hinder pluralistic perspectives from unique backgrounds and life experiences. In the present reflective report, I aim to conduct quantitative and qualitative research on myself to explore the impact of concentrating on genuineness when delivering psychotherapy as a trainee. This article provides concrete examples of how therapists’ authenticity could benefit the therapeut [...]

by Rouvick M Gama  , Mysore Phanish  , Abbas Ghazanfar  and Debasish Banerjee

Received: 09 January 2023;  Published: 23 May 2023;  doi: 10.21926/obm.transplant.2302185

Despite preventative measures, including vaccination, severe acute respiratory syndrome coronavirus (SARS-CoV-2) infection may result in severe illness, particularly in immunosuppressed transplant recipients. This has had a negative impact on organ donation and transplantation rates. However, the risk of transmission from SARS-CoV-2 positive donors to kidney transplant recipients is unknown. We describe 2 cases of successful kidney transplantation from SARS-CoV-2 positive donors. Case 1: 38-year old unvaccinated fe [...]

by Suat Morkuzu  , Alice Morello  , Giorgio Raposio  and Edoardo Raposio

Received: 18 July 2024;  Published: 27 November 2024;  doi: 10.21926/obm.neurobiol.2404258

Recent studies have identified that certain types of migraines, including frontal migraines, may be attributed to the irritation of specific extracranial nerves. This systematic review addresses the following questions: Which surgical techniques are most effective for chronic frontal migraines? How do combined surgical approaches compare to isolated procedures regarding efficacy and complication rates? Our objective is to comprehensively analyze surgical options for frontal migraines, including their success rates [...]

by Amanda Pong  and Pavel Klein

Received: 15 February 2024;  Published: 08 May 2024;  doi: 10.21926/obm.genet.2402234

Tuberous sclerosis complex (TSC) is caused by mutations of hamartin (TSC1) or tuberin (TSC2) resulting in disinhibition of the mTOR pathway of cellular proliferation and differentiation and severe neurocognitive impairment, intractable epilepsy and tumors. Epilepsy develops in ~90% folllowed by drug-resistant epilepsy (DRE). Recently, prevention of DRE and developmental encephalopathy was shown to be possible in TSC using early administration of vigabatrin. For the first time, medical treatment successfully prevent [...]

by Ashwini Arjuna  , Deepika Razia  , Devika Sindu  , Michael T. Olson  , Lara Schaheen  , Ross M. Bremner  , Rajat Walia  and Kendra McAnally

Received: 25 October 2022;  Published: 06 January 2023;  doi: 10.21926/obm.transplant.2301173

Few reports have described successful lung transplantation from a donor with a history of SARS-CoV-2 infection, and outcomes beyond 3 to 6 months remain unknown. After weighing the urgency and life-saving benefits of lung transplantation against the risk of viral transmission, we successfully performed a bilateral lung transplant from a donor with confirmed SARS-CoV-2 infection with mild symptoms 2 months before donation. At 1 year after transplant, there is no evidence of donor-derived viral transmission, and allo [...]

by Daphna Markman Zinemanas

Received: 09 November 2023;  Published: 29 November 2023;  doi: 10.21926/obm.icm.2304057

The experience of painting during the COVID-19 period initiated this art-based autoethnographic account. The pandemic affected various fields of life; the discussion is thus pursued from a few interrelated points of view: of an individual coping with the COVID-19 crisis on a personal level, of a painter, of an art therapist, of an art therapy lecturer and supervisor, and an artist involved in community interventions. Artmaking and viewing artworks can enhance communication with the beholder and encourage others to [...]

by Luana Góes Soares  , Sandra Kunst  , Cláudia Trindade Oliveira  and Annelise Kopp Alves

Received: 04 February 2024;  Published: 01 July 2024;  doi: 10.21926/cr.2403007

Sustainability has driven the use of heterogeneous photocatalysis as one of the primary methods for environmental decontamination, reduction, degradation, remediation, or transformation of polluting chemical residues and purification treatment of effluents and wastewater. TiO2 is the most commonly used semiconductor in heterogeneous photocatalysis. It acquires relevance, as it has favorable properties, such as non-toxicity, stability in a wide range of pH, economic viability, etc., which encourage its application a [...]

by Shisir Ruwali  , Bharana Ashen Fernando  , Shawhin Talebi  , Lakitha Wijeratne  , John Waczak  , Prabuddha M. H. Madusanka  , David J. Lary  , John Sadler  , Tatiana Lary  , Matthew Lary  and Adam Aker

Received: 19 December 2023;  Published: 08 May 2024;  doi: 10.21926/aeer.2402011

Breathing clean air is crucial for maintaining good human health. The air we inhale can significantly impact our physical and mental well-being, influenced by parameters such as particulate matter and gases (e.g. carbon dioxide, carbon monoxide, and nitrogen dioxide). Building on previous research that explored the effects of particulate matter (PM) in specific environments, analyzed using biometric indicators and machine learning models; this work focuses on the effects and estimation of inhaled nitrogen dioxide ( [...]