by Pierfrancesco Morganti  , Gianluca Morganti  , Maria Beatrice Coltelli  , Wladimir E Yudin  , Hong-Duo Chen  and Alessandro Gagliardini

Received: 16 March 2022;  Published: 23 May 2022;  doi: 10.21926/aeer.2202021

Approximately 75% of textile waste is generated annually worldwide, as there is a dearth of viable recycling strategies. It has been estimated that textile industries can be responsible for approximately 20% of global water pollution. As a consequence, if not properly managed, the cost of waste management of textile waste will be trillions of dollars annually. Moreover, the generated wastes are detrimental to the environment and public health. On the other hand, there is a possibility that the majority of the waste [...]

by Fawzy Georges

Received: 21 April 2020;  Published: 13 August 2020;  doi: 10.21926/obm.genet.2003115

The challenges which face the world today can be summed up in a few words: An increasingly congested world with dwindling areas of viable cultivated land and accelerating climate instability. The combined effect of these realities, together with the trend of striving to extend the average human life, puts the world on the path toward future catastrophe. This situation makes it imperative to seek realistic and practical solutions, which must be able to address food shortages and climate problems in a timely manner. [...]

by Jean Youngwerth  , Heather Coats  , Amy Jones  , Angela Wibben  , Elizabeth Somes  , Sue Felton  , Ashley Anderson  , Kathleen Flarity  , Kellar Elliot  and Jean Kutner

Received: 17 November 2019;  Published: 14 January 2020;  doi: 10.21926/obm.icm.2001004

The University of Colorado Hospital (UCH) implemented a Creative Arts Therapy (CAT) program offering CAT to hospitalized patients as a component of comprehensive palliative care (PC) services. The objective of this pilot program evaluation study was to evaluate short-term effects of CAT on patient symptoms and patient/family perceptions regarding their experience. The sample included adult patients hospitalized in an academic medical center who were seen by the Palliative Care Consult Service (PCCS) between October [...]

by Darren E. Stewart  , Amber R. Wilk  and David K. Klassen

Received: 14 December 2018;  Published: 22 January 2019;  doi: 10.21926/obm.transplant.1901041

Background: This study examines very recent trends in deceased donor kidney transplantation to assess the performance of the kidney allocation system (KAS), implemented December 4, 2014, and whether bolus effects associated with KAS have stabilized nearly four years after implementation. Methods: The overall number of deceased donor kidney transplants, as well as the proportion of transplants by recipient and transplant characteristics, were calculated monthly from December 2013 through September 2018 and examined [...]

by Stamatia Stai

Received: 27 May 2018;  Published: 06 September 2018;  doi: 10.21926/obm.genet.1803032

Immunoglobin A Nephropathy (IgAN) is the most common primary glomerulonephritis worldwide. Its development is characterized by the deposition of immune complexes that consist of abnormally galactosylated IgA1 molecules and IgG or IgA autoantibodies in the mesangium and the subsequent induction of renal injury. Recent research has shed light to many aspects of the pathogenesis of the disease, including the contribution of epigenetic modifications in its onset and progression. This review aims to present some of the [...]

by Sharon Clevenger

Received: 02 April 2020;  Published: 18 May 2020;  doi: 10.21926/obm.icm.2002031

The novel coronavirus COVID-19 is a viral pathogen that first emerged in Wuhan, China in 2002 and has spread to 202 countries (as of March 28, 2020) [1]. Despite the fact that the 2005 SARS-CoV pandemic infected over 8,500 people, and caused over 800 deaths with billions of dollars in economic loss worldwide, as of 2015 there were still no clinically approved antiviral drugs, vaccines or monoclonal antibody therapies to treat SARS-CoV infections [2]. Antiviral medications that have been used to treat or control oth [...]

by Ji-Jie Pang  and Samuel M. Wu

Received: 24 November 2020;  Published: 21 May 2021;  doi: 10.21926/obm.neurobiol.2102098

We studied how GC death in glaucoma related to the intraocular pressure (IOP), eyeball volume (VS) and elasticity (volumetric KS and tensile ES), and eyeball volume-pressure relation. Glaucomatous GC loss was studied in DBA/2J (D2) mice with wild-type mice as controls. GCs were retrogradely identified and observed with a confocal microscope. The elasticity calculation was also done on published data from patients treated by a gas bubble injection in the vitreous cavity. The GC population in D2 mice (1.5- to 14-mont [...]

by Yulia Salamatova  and Andreja Packard

Received: 24 June 2021;  Published: 20 December 2021;  doi: 10.21926/obm.neurobiol.2104111

Circadian rhythms are 24-hour cycles of physical, mental, and behavioral changes regulated and maintained by the internal primary circadian clock, however modifiable by a number of external cues or “zeitgebers”, the most powerful one being light. Core set of clock genes regulate the whole-body metabolism and transcription of over 40% of mammalian RNA, including that for drug transporters, binding and metabolizing proteins responsible for regulation of pharmacokinetics of vast array of medications. Growing amount of [...]

by Aly Mousaad Aly  and Milad Rezae

Received: 26 December 2020;  Published: 04 March 2021;  doi: 10.21926/jept.2101011

During their lifecycle, wind turbines can be subjected to multiple hazard loads, such as high-intensity wind, earthquake, wave, and mechanical unbalance. Excessive vibrations, due to these loads, can have detrimental effects on energy production, structural lifecycle, and the initial cost of wind turbines. Vibration control by various means, such as passive, active, and semi-active control systems provide crucial solutions to these issues. We developed a novel control theory that enables semi-active controller tuni [...]

by Scott A. Trudeau  and Megan E. Gately

Received: 08 February 2021;  Published: 30 April 2021;  doi: 10.21926/obm.geriatr.2102169

The Reading Buddies Program was developed as a service-learning component of an Occupational Therapy Practice with Older Adults course as a collaboration between Tufts University and the VA Bedford Health Care System. The purpose of this service-learning program was to challenge graduate students’ implicit biases and improve communication skills when working with older adults with significant cognitive impairments. Through this collaboration, occupational therapy students provided individualized, activity-based car [...]

by Joseph P. Green  , Steven Jay Lynn  , Olivia J. Green  , Victoria R. Bradford  and Rouhangiz Rasekhy

Received: 18 February 2020;  Published: 11 May 2020;  doi: 10.21926/obm.icm.2002029

Since Charcot [1], researchers and theorists have associated hypnotic responsiveness with dissociation. However, contemporary researchers have typically not documented impressive or statistically significant correlations between the most commonly used measure of dissociation, the Dissociative Experiences Scale-II [2, 3] and hypnotic responsiveness. We examined the ability of two measures of non-pathological dissociation, which have received scant attention in the hypnosis literature, the Wessex Dissociation Scale ( [...]

by Kohl Jacobson  , Sam Strassler  , Courtney Spalt  , Sara Henry  , Arthur Powers  and Donald W. Radford

Received: 22 December 2020;  Published: 29 March 2021;  doi: 10.21926/rpm.2101008

Continuous fiber reinforced geopolymer matrix composites offer the potential for use in structural applications at temperatures up to 700°C, while enabling the manufacture at temperatures below 100°C. Studies have investigated a variety of high temperature structural fiber reinforcements, including carbon, SiC and Al2O3. While there has been active research into various grades of Al2O3 fibers, SiC is most commonly used for high temperature reinforcement of geopolymers in oxidizing environments. Both familie [...]

by Rene J. Duquesnoy  and Marilyn Marrari

Received: 13 December 2019;  Published: 10 February 2020;  doi: 10.21926/obm.transplant.2001099

Many studies have demonstrated that HLA-DR, HLA-DQ and HLA-DP matching at the eplet level reduces allograft rejection and improves transplant outcome. Such studies have examined the eplet effect for the individual class II loci, but until now little attention has been given to so-called interlocus class II eplets shared between HLA-DR, HLA-DQ and/or HLA-DP alleles. This report summarizes current information about antibody-verified interlocus class II eplets. It describes a structural modeling method to determine po [...]

by Ashrit Multani  and Stanley Deresinski

Received: 31 October 2018;  Published: 27 December 2018;  doi: 10.21926/obm.transplant.1804035

Strongyloides stercoralis, an intestinal parasitic nematode (roundworm), infects more than 100 million people worldwide. While most infected immunocompetent persons are either asymptomatic or experience only mild, intermittent symptoms, immunosuppressed individuals, including those undergoing solid organ transplantation, are at increased risk for developing the frequently fatal hyperinfection syndrome. Donor-derived strongyloidiasis has recently become increasingly recognized and reported but current donor screenin [...]

by Lorraine Cowley  and Mari Jones

Received: 30 December 2019;  Published: 26 April 2020;  doi: 10.21926/obm.genet.2002108

This paper explores views of healthcare professionals (HCPs) in genetics and foetal medicine settings on offering pre-natal diagnosis (PND) for adult onset cancer susceptibility (AOCS) genes. Study participants came from different disciplinary backgrounds and all had considered implications of offering PND for AOCS, directly or indirectly, from professional and personal perspectives. Foetal medicine and genetics teams are accustomed to offering PND with the possibility of terminating an affected foetus on the basis [...]

by Laura Privalle  , Patricia Back  , Apurv Bhargava  , Zach Bishop  , Krystal Cisneros  , Isabelle Coats  , Ine Criel  , Lien Dhondt  , Travis Draughn  , Barb Fowler  , Brad Franklin  , Durba Ghoshal  , Jim Lor  , Jennifer Massengil  , Sofie Moens  , Tyson Mooney  , Dannyel Nelson  , Karolien Peeters  , Sashi Sathischyandra  , Caroline Staut  , Yoonhui Sung  , Ann Tuttle  , Annelies Van Hoecke  , Annelies Van Raemdonck  , Marie-Laure Verdegem  , Steven Verhaeghe  , Shane Walsh  , Ann Wierckx  , Qiang Zhao  and Rozemarijn Dreesen

Received: 11 September 2020;  Published: 02 December 2020;  doi: 10.21926/obm.genet.2004120

Demonstration of the stability of traits newly introduced into a plant genome via genetic engineering approaches comprise a significant portion of the safety assessment that these products undergo prior to receiving the requisite regulatory approvals enabling commercial authorization. Different regions of the world have different regulatory requirements and many ask similar questions from multiple and overlapping perspectives. The entire central dogma, that is stability at the DNA level, mRNA level and protein leve [...]

by Walid AL-ACHKAR  , Manar As’sad  , Thomas Liehr  , Adnan Ikhtiar  and Abdulsamad Wafa

Received: 14 August 2018;  Published: 20 June 2019;  doi: 10.21926/obm.genet.1902081

Background: The aggressive T-cell acute lymphoblastic leukemia (T-ALL) is one of the frequently occurring malignancies of the thymocytes. T-ALL is observed in 15% and 25% of all new diagnosed ALL cases in children and adults, respectively. Notably, T-ALL has a 3-fold higher incidence in males than in females. In nearly half of T-ALL cases, structural and/or numerical chromosomal abnormalities are detected, which have an important prognostic significance. A well-known genetic subtype of B-ALL, high hyperdiploidy (He [...]

by Katia Belvedere  , Elio Rossi  , Mariella Di Stefano  and Sonia Baccetti

Received: 22 February 2019;  Published: 10 April 2019;  doi: 10.21926/obm.icm.1902022

Complementary Medicine (CM) is being increasingly used by European citizens in order to increase their overall state of health and well-being, as well as to treat various illnesses and diseases. The interest for these therapies has progressively risen also in Italy and in Tuscany as well. In response to the increasing demand in the past few years by the Tuscan citizens, the region of Tuscany has started their integration in the healthcare service. Since 1996, the Tuscan Regional Healthcare Plans (RHPs) have been co [...]

by Andreas Miles-Novelo  and Craig A. Anderson

Received: 30 August 2022;  Published: 24 May 2023;  doi: 10.21926/aeer.2302034

As the climate crisis has progressed, scientists have begun to ask, "How does a rapidly warming ecosystem impact human behavior?" As aggression scholars and non-professional environmentalists, it has become increasingly clear that the impact of the climate crisis, without intervention, will dramatically increase humans' exposure to risk factors known to cause aggressive and violent behavior. This article describes a model that explains the indirect and direct effects of the climate crisis on aggression and violence [...]

by Olga Zichnali  , Despina Moraitou  , Christos Pezirkianidis  and Anastasios Stalikas

Received: 30 October 2018;  Published: 03 April 2019;  doi: 10.21926/obm.geriatr.1902044

Background: Interventions that facilitate positive actions and attitudes seem to play an important role in enhancing psychological health. This study examines the effectiveness of two self-guided interventions with the aim to enhance adults’ well-being through the cultivation of forgiveness skills. Methods: A total of 11 men and 31 women aged 34-80 years were involved (M = 56.57, S.D. = 13.44). All participants were Orthodox Christians, as the average Greeks are, without belonging to a closed religious community. T [...]

by Maria E. Pushpanathan  , Andrea M. Loftus  , Natalie Gasson  , Meghan G. Thomas  and Romola S. Bucks

Received: 13 May 2019;  Published: 23 September 2019;  doi: 10.21926/obm.geriatr.1903075

Background: Both disrupted sleep and cognitive impairment are frequent in Parkinson’s disease (PD), but the evidence for a relationship between self-reported sleep disturbance and cognitive symptoms has been equivocal. If sleep symptoms differentially predict cognition in different subtypes, effects may be obscured in a general PD sample. Objective: First, to determine whether the associations between participant and disease variables, sleep symptoms and cognitive performance vary by subtype (younger and olde [...]

by Lauren Ferguson  , Justin Cantrelle  and Paul Loprinzi

Received: 06 September 2018;  Published: 17 December 2018;  doi: 10.21926/obm.icm.1804034

Background: The present study evaluates the effects of selective directed forgetting (SDF) and directed forgetting (DF) on subsequent memory retrieval and investigate whether acute exercise can facilitate the effects of SDF. Methods: A four-arm (n=20 per group; N=80; Mage=20 yrs), parallel-group, randomized controlled experiment was employed. The four groups included: 1) exercise plus SDF (Ex+SDF), 2) SDF only (SDF), 3) DF only (DF) and 4) R (remember) only (R). Participants viewed two separate word lists (list 1 a [...]

by Waqar Husain  , Farrukh Ijaz  , Muhammad Ahmad Husain  , Marwa Zulfiqar  and Javeria Khalique

Received: 20 December 2023;  Published: 23 January 2024;  doi: 10.21926/obm.icm.2401011

The assessment of mental health and mental disorders has undergone extensive exploration within the field of psychology, resulting in various models and approaches. In addition to traditional ways like the Diagnostic and Statistical Manual of Mental Disorders, psychologists have proposed alternative perspectives for evaluating mental health. One such innovative approach is the psychosocial health model, which defines mental well-being as sexual, emotional, social, environmental, cognitive, religious, moral, and spi [...]

by Joan Weiss  , Nina Tumosa  , Robert Espinoza  , Elizabeth Bragg  , Jennifer Craft Morgan  , Jason D. Flatt  , Eleanor S. McConnell  and Grace Whiting

Received: 12 November 2020;  Published: 16 March 2021;  doi: 10.21926/obm.geriatr.2101162

This policy paper presents workforce development recommendations for research, clinical care and public stakeholders as they plan future research activities to strengthen the workforce to support the healthcare and social needs of persons living with dementia and their families and caregivers. To create these recommendations, the 2020 National Research Summit on Care, Services and Supports for Persons with Dementia and Their Caregivers (2020 Summit) convened a Workforce Development Stakeholder Workgroup. The Stakeh [...]

by Avneet K. Mangat  and Georg M. Schmölzer

Received: 07 June 2019;  Published: 20 August 2019;  doi: 10.21926/obm.icm.1903051

The incidence of Neonatal Abstinence Syndrome (NAS) is increasing due to more mothers using illicit drugs. This results in an increase in costs and resources for the healthcare system. Newborns with NAS might experience withdrawal symptoms that can cause pain, distress, and may potentially increase the risk of future health complications. It is therefore important to find effective treatments that can alleviate NAS. Various non-pharmacological treatments are used in conjunction with pharmacological treatments to re [...]

by Niamh Flynn

Received: 01 July 2019;  Published: 26 September 2019;  doi: 10.21926/obm.icm.1903057

Hypnosis interventions consistently produce significant decreases in pain associated with a variety of chronic-pain problems (Elkins, Jensen & Patterson 2007) while neurophysiological studies have shown that specific hypnotic suggestions have clear effects on the brain and spinal cord functioning (Jensen & Patterson 2014; Flynn, 2019). Thus, it isuseful for clinicians who practise hypnotherapy to understand pain paradigms.

by Ciro Comparetto  , Florence Dupré  and Franco Borruto

Received: 15 July 2019;  Published: 12 December 2019;  doi: 10.21926/obm.genet.1904101

Background: Clinical or medical genetics deals with the study and diagnosis of genetic diseases. It is oriented to the formulation of the clinical diagnosis of genetic diseases and genetic counseling to evaluate the possible reproductive risk for the patient and his/her family. The geneticists here play a role in the diagnosis and prevention of some of the diseases occurring most frequently, such as cancer and cardiovascular diseases. Methods: State-of-the-art through literature review. Results: Genetic counseling [...]

by Demelza Emmerton  , Samra Khan  , Joanne Conway  , Daniel Mosby  and Ahmed H. Abdelhafiz

Received: 31 May 2020;  Published: 10 July 2020;  doi: 10.21926/obm.geriatr.2003127

With life-expectancy rising globally, the prevalence of ageing, comorbidity and frailty is likely to increase especially in the low and middle income countries. The emergence of the new COVID-19 pandemic has been concentrated in this group of patients and has led to worse outcomes compared to younger and less comorbid populations. This group of patients is at an increased risk of multi-organ consequences of systemic disease. Therefore, systemic assessment of these patients from the outset and optimisation of their [...]

by Amanda Baker

Received: 04 May 2020;  Published: 07 August 2020;  doi: 10.21926/obm.neurobiol.2003069

Psychiatry is seeking interventions that could reliably sustain weight gain and psychosomatic recovery of patients with severe anorexia nervosa (AN). Currently, patients with AN, even after receiving individually-tailored therapeutic interventions, often relapse following marginal weight restoration. Also, the evidence regarding the effectiveness of psychotropic medications in relieving and treating AN symptomology is limited. The research in the field is aiming to mitigate shortcomings associated with common pract [...]

by C. Lange-Küttner  and Donna S. Martinez-Claras

Received: 21 August 2019;  Published: 26 February 2020;  doi: 10.21926/obm.neurobiol.2001050

We investigated whether healthy older adults who live in female-dominated old age care homes can identify the gender of male and female faces of people from different ethnicities in the same way as young adults. We hypothesized that this mainly female environment would lead by exposure to a female-gender bias. A sample of 40 participants aged 20-30 and 70-80 years identified the sex-of-face of 120 images of young and old adults, male and female faces, black and white faces, presented in a randomized sequence in a s [...]

by Melita Vidakovic  , Jessica Marinello  , Maija Lahtela-Kakkonen  , Daumantas Matulis  , Vaida Linkuvienė  , Benoît Y. Michel  , Ruta Navakauskiene  , Michael S. Christodoulou  , Danielle Passarella  , Saulius Klimasauskas  , Christophe Blanquart  , Muriel Cuendet  , Judit Ovadi  , Stéphane Poulain  , Fabien Fontaine-Vive  , Alain Burger  and Nadine Martinet

Received: 30 May 2018;  Published: 16 August 2018;  doi: 10.21926/obm.genet.1803029

Background: With their varied pharmacophores, natural products are interesting tools to open the drug discovery pipeline. Several plant secondary metabolites are components of the human diet and have reported epigenetic activities. In this study, we screened a small natural compound library for epigenetic activities. Methods: Seventy-one different natural products plus 17 controls collected from all collaborating laboratories were screened. Localized DNA methylation (DNAm) was studied on a stretch of the retinoic a [...]

by Stephanie Bryan  , Maryellen Hamilton  and Elizabeth Finn

Received: 21 February 2018;  Published: 15 May 2018;  doi: 10.21926/obm.icm.1802006

Purpose: High levels of mindfulness correspond with some positive health behaviors such as exercise participation, fruit and vegetable intake, and effective stress management. This study provided mindfulness meditation during an academic semester to a group of predominantly minority college students derived from a population in which 77.9% of the students are considered economically disadvantaged, to assess the effects of mindful meditation on various health behaviors and mindfulness to combat avoidable health ineq [...]

by Joep Geraedts

Received: 05 June 2018;  Published: 23 July 2018;  doi: 10.21926/obm.genet.1803024

Both preimplantation genetic testing (PGT) and prenatal diagnosis (PND) are powerful tools to tackle the transmission of inherited disorders carried by families from generation to generation. Here, we present an overview of the current landscape of both methods and identify the pros and cons of each of these reproductive options. In prenatal testing, non-invasive diagnostic methods have become available as an alternative for invasive diagnosis. Different genome sequencing strategies have now been introduced that en [...]

by Hagit Daum  , Simcha Yagel  and Mordechai Shohat

Received: 11 March 2019;  Published: 15 May 2019;  doi: 10.21926/obm.genet.1902077

Background: Fetal exome sequencing is becoming a crucial modality for genetic investigation whenever fetal malformations are documented in the context of normal chromosomal microarray analysis (CMA). When ultrasound findings are non-specific, the robustness of exome sequencing may be the only way to achieve a molecular diagnosis during pregnancy. Case: We describe a case of multiple non-specific fetal findings with the eventual diagnosis of fetal Kabuki Syndrome by exome sequencing. Conclusions: This case stresses [...]

by Stefania Policicchio  , Emma L Dempster  and Therese M Murphy

Received: 20 June 2018;  Published: 06 October 2018;  doi: 10.21926/obm.genet.1804039

Suicide is the second leading cause of death globally among young people and the tenth leading cause of death across all ages. Approximately 800,000 people die by suicide every year representing a significant global health burden. Despite this burden, the molecular pathology of suicide remains poorly understood. A number of recent studies have shown that epigenetic alterations are associated with suicidal behaviour. These epigenetic mechanisms, which act to regulate gene expression via modifications to DNA, histone [...]

by Natalia Sylvia Ramos Díaz

Received: 23 August 2018;  Published: 14 March 2019;  doi: 10.21926/obm.icm.1901017

One of the objectives of psychological intervention is to help patients manage their emotions effectively by providing them with the necessary skills to accompany their own emotional states. To this regard, there seems to be a current lack of therapeutic resources aimed at helping patients assimilate and regulate emotions. This article proposes the application of a new technique which incorporates mindfulness, building on the premises of the model of psychological flexibility which defines "mindfulness" as a practi [...]

by Xi Chen  and Jianhua Xuan

Received: 19 October 2019;  Published: 07 April 2020;  doi: 10.21926/obm.genet.2002107

The analysis of gene networks and signalling pathways plays a key role in understanding gene functions, i.e., their effects on the development of a particular disease. Yet, for many heterogeneous diseases, the number of known disease-associated genes is limited. Identifying disease-associated genes is still an open challenge. To understand the functions of genes associated with a disease, we develop a Metropolis-Hastings sampling based SIGnificant NETwork (MSIGNET) identification approach. MSIGNET integrates diseas [...]

by Holly Hazlett-Stevens

Received: 20 April 2018;  Published: 29 September 2018;  doi: 10.21926/obm.icm.1804023

Background: Mindfulness-Based Stress Reduction (MBSR) is an evidence-based intervention developed to teach mindfulness meditation to a wide range of patients. Although the efficacy of MBSR has been established for a variety of medical and psychiatric conditions, measured outcomes rarely include physical symptoms related to anxiety, depression, and/or stress. The current study presents a secondary analysis of data obtained from patients seeking MBSR for symptoms of anxiety, depression, and/or other stress-related co [...]

by Kristin Shrader-Frechette

Received: 09 February 2022;  Published: 17 August 2022;  doi: 10.21926/aeer.2203031

Many multinational retail companies are exposed to financial risk related to climate change. Carbon management is important in keeping global temperature increases below 1.5°C to prevent the exacerbated impacts of climate change. Auchan Retail in Auchan Holding provides a good example of carbon management in the retail sector. Auchan Retail's major emissions are the indirect emissions throughout their value chain (scope 3 emissions). The total estimated emission of scopes 1, 2 and 3 are 37,822,573.9 t CO2e. [...]

by Niklas Gudowsky  , Ulrike Bechtold  , Leo Capari  and Mahshid Sotoudeh

Received: 31 January 2019;  Published: 27 June 2019;  doi: 10.21926/obm.geriatr.1902058

Background: Quality or healthy aging refers to well-being in an older age. In the light of recent changes in the discourse on approaches on positive aging, we aimed to study the way “quality aging” is understood, expressed, and dealt with as a part of contemporary technology assessment (TA), since the nexus between demographic and technological changes has remained a staple topic in TA for at least three decades. Methods: A bottom-up qualitative content analysis was performed to identify the concepts of [...]

by Athanasia Soultana  , Michael Galetakis  , Anthoula Vasiliou  , Konstantinos Komnitsas  and Despina Vamvuka

Received: 11 February 2021;  Published: 17 August 2021;  doi: 10.21926/rpm.2103035

Waste concrete is the most predominant constituent material among construction and demolition waste. Current waste concrete recycling is limited to the use of recycled concrete aggregates as a road-base material and less as aggregates in new concrete mixes. Further, the production of recycled concrete aggregates results in the generation of a high amount of fines, consisting mainly of cement paste particles. Hence, this study aims to produce the cement mortars using the upgraded recycled concrete aggregates (sand g [...]

by Parisa Gazerani

Received: 09 May 2018;  Published: 10 October 2018;  doi: 10.21926/obm.genet.1804040

Interactions between genetic and environmental factors in migraine are well known and can potentially determine an individual’s susceptibility to disease and responsiveness to treatment. Consequently, several epigenetic studies have been conducted to determine if and how genes are activated or inactivated in response to a diverse range of environmental migraine triggers. The results, in turn, have helped elucidate how these factors can promote or inhibit migraine progression or therapeutic response and can guide de [...]

by Anne-Marie Laberge  and Wylie Burke

Received: 30 July 2017;  Published: 21 September 2017;  doi: 10.21926/obm.genet.1703006

Genetic screening is the process of systematically evaluating a defined population for genetic conditions or predispositions, in the hope of providing benefit to those with a positive result. With advances in sequencing technology, genetic screening is moving from phenotype-based to genotype-based testing. Although sequencing technology offers expanded opportunities for early identification of disease, the availability of a suitable and acceptable test is not a sufficient justification to proceed: established crite [...]

by Paulo Henrique Fernandes de Oliveira  and Reginaldo de Carvalho Silva Filho

Received: 29 December 2019;  Published: 15 April 2020;  doi: 10.21926/obm.icm.2002021

Rosacea is a chronic inflammatory disease of the skin characterized by facial papules, pustules, erythema, and telangiectasia. Emotional factors such as stress and anxiety may induce and aggravate the symptoms of rosacea. It is hypothesized that tongue acupuncture, a technique that has been used successfully in the treatment of various neurological and psychiatric diseases, could be beneficial in relieving rosacea symptoms. This study evaluated the immediate effect of tongue acupuncture at specific anatomical point [...]

by Leonel Pereira  and Ana Valado

Received: 06 March 2024;  Published: 10 May 2024;  doi: 10.21926/obm.neurobiol.2402223

This review explores the potential of compounds derived from red algae (Rhodophyta) as promising neuroprotective agents for treating neurodegenerative disorders. Red algae, abundant in marine environments, contain bioactive compounds with diverse chemical structures and functionalities. Sulfated polysaccharides, primarily agar and carrageenans, stand out as the predominant and widely utilized compounds derived from red algae. Additionally, red algae harbor a spectrum of potential molecules such as essential fatty a [...]

by Malcolm Voyce

Received: 22 July 2020;  Published: 16 November 2020;  doi: 10.21926/obm.transplant.2004124

This article aims to describe the relationship between donors and their recipients in the context of organ transplants. This analysis is made in the light of Marcel Mauss’s work, offering an expansion on an analysis of his discussion on the “spirit of the gift” and his idea that gifts require reciprocation. It is argued that some recipients of donated organs receive a personal element from the donor in that there is a transfer or sharing of the donors’ personality and spiritual qualities. The article examines the n [...]

by Luis Delaye

Received: 05 May 2019;  Published: 11 July 2019;  doi: 10.21926/obm.genet.1903083

Background: Phylogenetic analysis shows that Pneumocystis have coevolved with their mammalian hosts for millions of years. As a result, infection by Pneumocystis is species specific (i.e. a given Pneumocystis species can infect only a single species of host). This specificity suggests the existence of a Red-Queen dynamic between Pneumocystis and its host. Evidence of this dynamic is provided by the molecular diversity and the elevated rate of non-synonymous versus synonymous (dN/dS) codon substitutions among Pneumo [...]

by Russell Razzaque

Received: 28 January 2018;  Published: 27 March 2018;  doi: 10.21926/obm.icm.1801001

The value of mindfulness for clinical staff in the mental health field has thus been increasingly recognised over recent year and thus is now culminating in the evaluation and, potential future role out, of whole system approaches like Open Dialogue that put clinician mindfulness at the heart of the model. It is anticipated that this will ultimately be for the benefit of both staff and clients of these services alike, creating improvements and improving lives, therefore, on many levels.

by Mariella Di Stefano  , Sonia Baccetti  , Elio Rossi  , Maria Valeria Monechi  , Barbara Cucca  , Sergio Segantini  , Elisabetta Barbara Cortesi  , Fabio Voller  , Eleonora Fanti  , Alice Berti  and Stefano Bravi

Received: 27 September 2018;  Published: 28 April 2019;  doi: 10.21926/obm.icm.1902029

Background: According to the international literature, users of Complementary Medicine (CM), Complementary and Alternative Medicine (CAM) and Complementary and Integrative Medicine (CIM) are physically more active, less overweight and have healthier lifestyles than the average Tuscan population. Aim: To evaluate the socio-demographic characteristics and lifestyles of patients of CM public clinics in the region of Tuscany and to define their profiles in terms of physical exercise, smoking habits, diet, intake of alc [...]

by Pras Ramluggun  and Sanj Nathoo

Received: 07 March 2019;  Published: 13 June 2019;  doi: 10.21926/obm.icm.1902036

The evolving, dynamic and challenging healthcare landscape requires that the art and science of nursing equip preregistration nursing students with the knowledge and skills to positively respond to these changes. Central to these students’ ability to demonstrate competence in the fundamentals of nursing care are core nursing attributes to meaningfully engage and attend to patients’ in delivering compassionate care and meeting their needs. The literature identifies the process of delivering compassionate care as a h [...]