by Noah J. Webster  , Kristine J. Ajrouch  and Toni C. Antonucci

Received: 05 December 2018;  Published: 12 May 2020;  doi: 10.21926/obm.geriatr.2002118

Forgiveness may serve as an essential positive resource to help individuals cope emotionally with stressful events, ultimately influencing health. Examination of how individuals forgive within the context of close relationships can provide useful information about positive aging. In this study, we examine how the severity of a recent transgression committed by a spouse/partner or other close social relationship is associated with self-reported physical health among older adults. We also examine how state forgivenes [...]

by Daicia Price  , Yatesha Robinson  , Hurley Riley  , Julie Ribaudo  , Chris Giang  , Todd I. Herrenkohl  and Alison L. Miller

Received: 21 March 2023;  Published: 21 November 2023;  doi: 10.21926/obm.icm.2304055

Adverse and traumatic childhood experiences can have profound negative health and mental health consequences across the lifespan. Prevention and early intervention strategies to mitigate such impacts and foster resilience are essential, yet extant approaches often do not consider the systemic nature of trauma exposure, particularly among communities most impacted by the COVID-19 pandemic and historic disinvestment. Addressing the impacts of trauma early in life is critical in order to mitigate their long-term effec [...]

by Mario Lefebvre

Received: 26 September 2022;  Published: 08 December 2022;  doi: 10.21926/aeer.2204049

A filtered Poisson process is proposed as a model for river flows. With the help of real-life data, the model parameters are estimated. Mathematical formulae are derived in order to estimate the various return periods of the river. An application to two rivers shows that the point estimates are very close to the corresponding values computed by hydrologists, based on historical data. Moreover, by modifying the values of the parameters in the model, we can see the potential effects of climate change on the return pe [...]

by Mary J. Lotesto  and Stacey L. Raimondi

Received: 26 June 2020;  Published: 07 October 2020;  doi: 10.21926/obm.genet.2004117

Estrogen-based cancers affect a substantial portion of the female population in the United States. While multiple studies have examined the effect of estrogen receptor alpha (ERα/ESR1) in cancer, the effects of ERβ/ESR2 are not as well understood in tumor tissues. Furthermore, there are few studies examining the role of specific binding partners of the estrogen receptors, such as early B-cell factor 1 (EBF1). EBF1 has been shown to have a role in B cell development and differentiation and is also know [...]

by Divya B. Mella  , Josie Sewell  and Edward Pan

Received: 12 October 2018;  Published: 01 November 2018;  doi: 10.21926/obm.neurobiol.1804014

Objective: To report three cases of refractory prolactinomas treated with Temozolomide (TMZ). Background: Prolactinomas account for 40% of pituitary adenomas. Dopamine agonists (DA) are the first line of treatment followed by surgical resection and radiation. TMZ is an oral chemotherapeutic agent used in gliomas, which has been given to patients with prolactinomas refractory to conventional treatments. Methods: Retrospective chart review was conducted for refractory prolactinoma patients treated between 2008 and 20 [...]

by Aurélie Laborel-Préneron  , Paulina Faria  , Jean-Emmanuel Aubert  and Camille Magniont

Received: 12 March 2021;  Published: 07 May 2021;  doi: 10.21926/rpm.2102016

Bio-based earth composites present various environmental benefits, such as usable wastes, coproducts, abundant or renewable materials, etc. Moreover, the incorporation of bioaggregates in the earth matrix allows the buildings to act as an effective carbon sink. A growing number of studies are now focusing on the mechanical and hygrothermal properties of bio-based earth building materials. However, the durability of these types of material is a major concern, and knowledge of their various aspects is essential to an [...]

by Peter Lechleitner

Received: 02 March 2018;  Published: 25 April 2019;  doi: 10.21926/obm.icm.1902027

The first part of this position paper focuses on the debate about the scientific status of homeopathy and presents some answers. The scientific debate however, does not represent the available scientific evidence, which actually supports our limited data. Thus, it seems important and we aim to present how homeopathy can be part of an integrated concept in cancer care and how this is approved by randomized controlled trials. We present some arguments which were helpful to us in the discussion with oncologists that d [...]

by Edmundo S. Valerio Neto  , Caio V.S. Almeida  , Giancarlo R. Salazar-Banda  and Katlin I.B. Eguiluz

Received: 24 November 2023;  Published: 11 March 2024;  doi: 10.21926/cr.2401003

In this study, we synthesized Pt-Rh nanowires (NWs) through chemical reduction of metallic precursors using formic acid at room temperature, excluding the use of surfactants, templates, or stabilizing agents. These NWs were supported on two substrates: carbon (Vulcan XC-72R) and carbon modified with tin oxide (SnO2) via the sol-gel method (10 wt.% SnO2). We explored the electroactivity of Pt/SnO2/C, Pt-Rh/C, Pt-Rh/SnO2(commercial)/C (commercial SnO2), and Pt-Rh/SnO2/C NWs toward electrochemical oxidation of ethanol [...]

by Laurence Pougnet  , Gilles Nevez  and Solène Le Gal

Received: 17 December 2018;  Published: 22 May 2019;  doi: 10.21926/obm.genet.1902080

Pneumocystis pneumonia (PCP) is the most frequent AIDS-defining disease among HIV-infected individuals in developed countries, and also affects immunocompromised non-HIV patients. Experimental studies on rodent models carried out in the early eighties have shown that Pneumocystis spp. can be transmitted via the airborne route. Unfortunately, this mode of acquisition and transmission has long been overlooked by physicians because PCP in immunosuppressed patients was considered to result from reactivation of a latent [...]

by Asaad G Ishak  , Sundar V Cherukuri  , GianCarlo Diaz  and Richard McCallum

Received: 25 January 2021;  Published: 02 July 2021;  doi: 10.21926/obm.geriatr.2103174

Dysphagia, or difficulty swallowing, is a common condition, especially among the elderly population and can become debilitating. As we age, there are subtle changes in esophageal motility, but by no means is dysphagia ever considered to be a normal result of aging. Dysphagia usually presents with a variety of accompanying symptoms ranging from regurgitation during meals, mild discomfort, to severe chest pain. It can be challenging to localize the dysphagia from the history. The underlying etiology may become eviden [...]

by Upama Majumder  , Samayeta Pramanik  , Mobasshara Uzma  , Kavya P R  and Debasish Kar

Received: 19 December 2024;  Published: 20 August 2025;  doi: 10.21926/rpn.2503016

Milk is best known as a nutrient-rich fluid produced by the mammary glands of mammals, designed primarily to feed young. In the human diet, cow milk is most prevalent, but milk of other mammals and plant milk are common too. This study aims to investigate milk's nutritional value in various age groups and review opposing evidence of its effect on cardiovascular diseases in adults. It is a literature-based strategy to synthesize information from observational and meta-analytic studies. The milk content—macronutrient [...]

by Niccolo Caldararo

Received: 19 October 2021;  Published: 11 January 2022;  doi: 10.21926/obm.genet.2201145

The evolution of hominins, members of the zoological tribe Hominini, has been a much-studied topic, and the construction of phylogenetic trees has been the key method in molecular evolutionary studies. How scientists determine the phylogenetic trees are governed by the assumptions they place on the construction of similarities and differences in morphological traits, the differences in the number of base pairs in the genomes, and the number of similar gene clusters that code for traits (haplotypes) or are error seq [...]

by Natalie G. Regier

Received: 04 December 2019;  Published: 17 February 2020;  doi: 10.21926/obm.geriatr.2001106

Neuropsychiatric symptoms (NPS) affect nearly all persons living with dementia (PLWD) at some point during the course of the disease. Given the absence of a cure or effective pharmacotherapy for dementia, it is particularly important to prevent, measure, track, and manage NPS in dementia care. Unfortunately, these efforts are hindered by inconsistent operational definitions and measurement tools for numerous neuropsychiatric symptoms. This review examines agitation, aggression, restlessness, and rejection of care a [...]

by Gunnel Berry

Received: 13 April 2018;  Published: 25 February 2019;  doi: 10.21926/obm.icm.1901012

Chronic pain is notoriously multifactorial, multifaceted and difficult to manage. Twenty per cent of reported whiplash-injured persons go on to develop a Whiplash Associated Disorder (WAD) where persistent pain becomes chronic with no prospect of change [1]. Paucity of effective therapies to address the effect of WAD enforces new approaches. This case report, with a patient’s perspective, illustrates a novel therapy, Adapted Reflextherapy (AdRx), which is akin to reflexology and has been used, developed and revised [...]

by Heizel Rosado-Galindo  and Maribella Domenech

Received: 15 March 2020;  Published: 14 May 2020;  doi: 10.21926/rpm.2002013

Cells can respond to different topographical cues in their natural microenvironment. Hence, scientists have employed microfabrication techniques and materials to generate culture substrates containing topographies for cell-based assays. However, one of the limitations of custom topographical platforms is the lack of adoption by the broad research community. These techniques and materials have high costs, require high technical expertise, and can leach components that may introduce artifacts. In this study, we devel [...]

by Yan Yang  and Gerhard Litscher

Received: 08 January 2020;  Published: 14 January 2020;  doi: 10.21926/obm.icm.2001003

Acupuncture, being a unique method, is a millennia-old tradition in the field of Chinese medicine. However, it is surprising that there are very few scientific publications on acupuncture and its gender-specific effects. This article summarizes the previous work from the perspective of both Western and Eastern medicine, involving manual acupuncture, electro-acupuncture, and modern innovative laser acupuncture. There is scientific evidence that future gender-specific considerations should be included in the assessme [...]

by Ameya Patil  , William E Sweeney  and Ellis D. Avner

Received: 07 August 2018;  Published: 23 December 2018;  doi: 10.21926/obm.genet.1804056

Renal cysts are present in a wide variety of hereditary renal diseases in children. The term polycystic kidney disease (PKD) refers to two specific hereditary diseases, distinguished by the usual age of onset and genetic cause: autosomal recessive polycystic kidney disease/congenital hepatic fibrosis (ARPKD/CHF, MIM *606702) and autosomal dominant polycystic disease (ADPKD-OMIM *601313 and OMIM *173910). ARPKD/CHF is characterized by cystic dilations of the renal collecting ducts and developmental defects of biliar [...]

by Ute Moog  and Domenico Coviello

Received: 14 August 2018;  Published: 13 September 2018;  doi: 10.21926/obm.genet.1803034

he publication of the double helix DNA structure in 1953 [1] was the kick-off of numerous efforts to understand and unravel the complexity of the human genome. It took 50 years until the human genome project, based on Sanger sequencing, was completed in 2003 [2]. This was followed by what may be considered a revolution in the field of DNA analysis: the introduction of Next Generation Sequencing (NGS) in 2005 consisting of massively parallel sequencing of DNA fragments which allows the high throughput analysis of la [...]

by Hironari Minami  , Hiroaki Izumi  , Takumi Hasegawa  , Fan Bai  , Daisuke Mori  , Sou Taminato  , Yasuo Takeda  , osamu yamamoto  and Nobuyuki Imanishi

Received: 30 June 2021;  Published: 23 September 2021;  doi: 10.21926/jept.2103041

Rechargeable batteries with higher energy and power density exceeding the performance of the currently available lithium-ion batteries are suitable for application as the power source in electric vehicles (EVs). Aqueous lithium-air batteries are candidates for various EV applications due to their high energy density of 1910 Wh kg-1. The present study reports a rechargeable aqueous lithium-air battery with high power density at room temperature. The battery cell comprised a lithium anode, a non-aqueous anode electro [...]

by Mega Obukohwo Oyovwi  and Edarho Oghenevwede Oyovwi

Received: 08 May 2024;  Published: 29 September 2024;  doi: 10.21926/obm.geriatr.2403290

Elder abuse is a hidden epidemic, with millions of older adults experiencing physical, psychological, or financial harm each year. However, the true extent of the problem is unknown due to under-reporting and lack of reliable data. This paper aims to provide an international perspective on the hidden epidemic of elder abuse, exploring the prevalence, risk factors, and consequences of this global issue. A systematic review of the literature was conducted using multiple databases. Studies from various countries were [...]

by Akira Nishimura  , Satoshi Ohata  , Kaito Okukura  and Eric Hu

Received: 25 March 2020;  Published: 14 May 2020;  doi: 10.21926/jept.2002008

Biogas is a promising resource for the production of H2 since it liberates energy by recycling waste, along with the reduction of CO2. In this paper, the biogas dry reforming membrane reactor is proposed to produce H2 for use in fuel cells. Pd/Cu alloy membrane is used to enhance the performance of the biogas dry reforming reactor. This study aims at understanding the effect of operating parameters such as feed ratio of sweep gas, pressure in the reactor, and reaction temperature on the performance of the biogas dr [...]

by Michelle F. Sener  , Thaddeus Rogozinski  , James S. George  , Deepak Mital  and Douglas P. Slakey

Received: 08 November 2022;  Published: 29 January 2023;  doi: 10.21926/obm.transplant.2301174

Cytomegalovirus (CMV) infection is the most common infection affecting kidney transplant recipients [1]. CMV may be present as asymptomatic viremia or with symptoms ranging from mild to significant tissue-invasive disease [1,2,3]. Optimal kidney graft function and survival requires that transplant care teams carefully assess individual patient risk of CMV [2,3]. Appropriate patient surveillance and prophylaxis are essential to ensure the best long-term kidney transplant results. Effective treatment of CMV disease r [...]

by Jacob Ladenburg

Received: 28 April 2020;  Published: 12 August 2020;  doi: 10.21926/jept.2003015

Visual external costs are significant elements in the cost-benefit analysis of wind farm locations. This has been demonstrated well in the literature. However, in the assessment of the visual costs, a large share of the earlier studies used no or only simplistic visualizations of the visual impacts at stake. The cost estimates thus rely on the respondents’ ability to imagine the visual impacts associated with wind turbines of different sizes and at different locations. This has been argued to potentially reduce the [...]

by O.A. Kornienko  , S.V. Yushkevych  , A.V. Sameljuk  and O.R. Andrievskaya

Received: 24 May 2021;  Published: 02 September 2021;  doi: 10.21926/rpm.2103036

The phase equilibria and structural transformations in the ternary ZrO2-CeO2-Eu2O3 system at 1500 °C were studied by X-ray diffraction and scanning electron microscopy in the overall concentration range. The system was found to constitute fields of solid solutions based on the tetragonal (T) modification of ZrO2, cubic (C) and monoclinic (B) modifications of Eu2O3, cubic with a fluorite-type structure (F) modifications of CeO2 (ZrO2), and ordered intermediate phase with a pyrochlore-type structure of Eu2Zr2O [...]

by Shih-Ang Hsu

Received: 25 July 2021;  Published: 02 September 2021;  doi: 10.21926/aeer.2103022

Spatial relation between wind stress and storm surge during two hurricanes in 2020 is investigated. It is found that, during Laura’s landfall, the area inside of 65 knots (34 m s -1) isotach or line of equal wind speed can produce up to 18 ft (5.5 m) inundation and during Delta, the area inside of 50 knots (26 m s -1) up to 11 ft (3.3 m) high water level above the ground. The tropical cyclone (TC) surface analysis near landfall by the Regional and Mesoscale Meteorology Branch (RAMMB) is recommended as a first [...]

by Isabella Zuccaroli  , Brandon Lucke-Wold  , Adhith Palla  , Alexander Eremiev  , Zachary Sorrentino  , Rasheedat Zakare-Fagbamila  , Jack McNulty  , Carlton Christie  , Vyshak Chandra  and David Mampre

Received: 16 November 2022;  Published: 22 February 2023;  doi: 10.21926/obm.neurobiol.2301158

Reported neuro-modulation schemes in the literature are typically classified as closed-loop or open-loop. A novel group of recently developed neuro-modulation devices may be better described as a neural bypass, which attempts to transmit neural data from one location of the nervous system to another. The most common form of neural bypasses in the literature utilize EEG recordings of cortical information paired with functional electrical stimulation for effector muscle output, most commonly for assistive application [...]

by Em V. Adams  , Brandi M. Crowe  , Jasmine Vanadore  , Marieke Van Puymbroeck  and Arlene A. Schmid

Received: 06 February 2022;  Published: 22 April 2022;  doi: 10.21926/obm.icm.2202020

The purpose of this descriptive survey was to explore how, and for what purpose, health care practitioners use yoga in clinical practice. A survey was administered to professionals who identified as healthcare practitioners who used yoga in their practice. There were 205 completed responses from a combination of healthcare practitioners including occupational therapists, physical therapists, yoga therapists, recreational therapists, speech-language pathologists, and mental health counselors. Practitioners worked in [...]

by Ayub Nor Hanin  , Mat Yunus Abdul Masani  , Ong-Abdullah Janna  , Omar Abdul Rasid  and Ghulam Kadir Ahmad Parveez

Received: 18 December 2024;  Published: 15 April 2025;  doi: 10.21926/obm.genet.2502292

Oil palm is the most productive vegetable oil crop compared to other oil-bearing crops because it produces the highest oil yield per hectare. Palm oil is very versatile since it is used for producing food and beverages, personal care and cosmetics, cleaning products, biofuel, and bioenergy. To cater to the increasing demand in the global palm oil market, much research has been done to improve the oil's yield and modify its quality in addition to the oil palm height through breeding. Due to its long breeding cyc [...]

by Nadia A. Abdelmegeed Abdelwahed

Received: 19 September 2023;  Published: 04 January 2024;  doi: 10.21926/obm.neurobiol.2401205

Entrepreneurial intention plays a pivotal role within entrepreneurship ecosystems, acting as a catalyst for economic growth and innovation by inspiring individuals to embrace entrepreneurship as a viable career pursuit. The present research delves into the intricate dynamics between stress, entrepreneurial intention, personal income, and physical health within Egypt's entrepreneurial landscape. Grounded in a quantitative analysis of 286 valid samples and utilizing SmartPLS 4, this study unveils compelling insights. [...]

by Margaret E. Newman  , Kenneth Pursell  and David Pitrak

Received: 05 November 2018;  Published: 20 January 2019;  doi: 10.21926/obm.transplant.1901040

Infection with parvovirus B19 is common, with up to 55% of adults showing seropositive evidence of prior infection. Clinical disease can occur due to acute infection, chronic persistent viremia, rarely secondary infection, or possibly viral reactivation of latent virus. The clinical presentation of primary infection depends on age, the presence of a hematologic condition, and immune status. We report a renal transplant recipient who developed transfusion dependent anemia refractory to erythropoietin that responded [...]

by Louguangshu Huang  , Hui Liu  , Xiaoxia Xue  , Wuduo Zhao  and Tiesheng Li

Received: 13 December 2021;  Published: 03 February 2022;  doi: 10.21926/cr.2201003

In this article, an approach to generate self-assembly cyclopalladated polythiophene imine monolayers (denoted as ITO@Pd-CPTIMs) is described. The monolayers were fabricated by combining self-assembly (SA), hybrid doping (HD), and electrochemical polymerization (ECP) called SA-HD-ECP. The catalytic activity and stability of the polymerized monolayers in the Suzuki coupling reaction were improved by modulating the structure and morphology in hybrid doping using different thiophene derivatives, concentrations, and sc [...]

by Ilaria Scarpelli  , Fabienne Marcelli  , Francesca Mattioli  and Jacqueline Schoumans

Received: 01 April 2019;  Published: 09 August 2019;  doi: 10.21926/obm.genet.1903088

With the advent of next-generation sequencing (NGS), genomic profiling of tumors has been gradually introduced into the clinical setting and has become a standard in cancer care. NGS allows convenient, rapid, and inexpensive sequencing and the commercially available NGS panels enable the detection of single or global genomic alterations of germline and somatic origin. Today, genomic mutation profiling using NGS is indispensable for disease evaluation and prediction of prognosis or responsiveness to cancer therapy. [...]

by Michael Fossel

Received: 29 January 2019;  Published: 30 January 2019;  doi: 10.21926/obm.geriatr.1901031

Telomere Editorial-Perspectives on Telomeres and Aging

by Krishanu Aich  , Sukrit Kashyap  , Konika Tyagi  , Ishika Verma  , Abhimanyu Chauhan  and Chakresh Kumar Jain

Received: 09 April 2022;  Published: 29 November 2023;  doi: 10.21926/obm.neurobiol.2304198

Today, the advancement of assessment, forecasting, and therapy or medical attention for psychological healthcare is already using artificial intelligence (AI) technology, particularly machine learning, due to the introduction of digital tools to treat mental health conditions. In mental health treatment, the present and the future of artificial intelligence technologies hold both enormous promises and potential dangers. With the current global scenario, psychological disorders like clinical depression, general anxi [...]

by Tobias Geis  , Ute Hehr  , Roland Brandl  , Saskia Herbst  , Hugo Segerer  , Michael Melter  and Sophie Hinreiner

Received: 31 August 2017;  Published: 06 March 2018;  doi: 10.21926/obm.genet.1801015

Background: Neonatal muscular hypotonia is a common clinical feature on neonatal intensive care units with a broad spectrum of etiologies. Besides more common and obvious underlying conditions like prematurity or Down syndrome many rare disorders with often poor prognosis need to be considered. Congenital brain malformations detected on ultrasound or/and magnetic resonance imaging might constitute the clinical hallmark in differential diagnosis. We report on our approach combining cerebral imaging and application o [...]

by Tina Huang  , Tony Hung  , S. Irene Kim  and Ka Kit Hui

Received: 07 October 2019;  Published: 02 March 2020;  doi: 10.21926/obm.icm.2001011

Acupuncture has increasingly been used to address a variety of symptoms in patients with cancer. Here we present a case to illustrate the use of acupuncture in a 35-year-old female with metastatic breast cancer who presented to the UCLA Center for East-West Medicine (CEWM) with physical and psychological symptom clusters of insomnia, anxiety, and joint pain.

by Oswaldo Núñez  , Mohammad Fereidooni  , Victor Márquez  , Duangthip Sattayamuk  , Piyasan Praserthdam  and Supareak Praserthdam

Received: 25 August 2023;  Published: 05 December 2023;  doi: 10.21926/cr.2304029

To improve CH4 and H2 formation from CO2 photoreduction using non-organic, non-laborious, and inexpensive photocatalysts, we have prepared two surface-silicate-modified TiO2 catalysts: P25-SiO2 and AmTiO2-SiO2 (amorphous TiO2) to be tested in water and using UV light. The last catalyst produces more CH4 and H2 in water than P25 (3:1 TiO2 anatase: rutile) under UV light irradiation of HCO3- and CO2; am-TiO2-SiO2 at pH = 7, produces 8 times more CH4 and H2 than P25 with selectivity at the reactor headspace of 30% and [...]

by Sara Schatz  and Melvin Gonzalez Rivera

Received: 15 March 2019;  Published: 13 August 2019;  doi: 10.21926/obm.geriatr.1903069

Pragmatic competence includes the capacity to express illocutionary force and successfully achieve perlocutionary effects, in order to guarantee fully functional communication exchanges. Improved pragmatic competence in patients has been found in patients with Mild Cognitive Impairment (MCI) and early to moderate Alzheimer’s Disease (AD) in the domains of jokes, self-expression and empathy after extended, targeted intranasal insulin therapy. In this paper it is argued that extended intra-nasal insulin treatment can [...]

by Luis A. Martínez  , Lizeth Rodríguez  , Carlos M. Flores  , Carlos A. Cisneros  , Mario W. Chávez  , Idis A. Lemus  and René I. Ariza

Received: 28 August 2022;  Published: 03 January 2023;  doi: 10.21926/aeer.2301001

Net zero energy building design methodologies include integrative approaches and numerical tools to provide optimal performance and cost-effective results. Team integration, characterized by knowledge transfer between disciplines, has yet to be quantified for the design processes of these buildings. This article proposes a specific methodology for designing net zero energy buildings, tested through a case study design process conducted in an academic setting at Universidad Centroamericana in El Salvador, with the p [...]

by Pawan Kumar Gautam  and Anoop Kumar Singh

Received: 11 July 2022;  Published: 30 January 2023;  doi: 10.21926/aeer.2301014

Tectonic geomorphology has been evidenced as an essential tool to define and measure recent tectonic deformation. The Nandakini River originates from Nanda Ghunti glacier at 6886 m in Lesser Himalaya. It covers about ~551 km2 basin area, with a fourth-order stream. It confluences with the Alaknanda River near Nand Prayag (at elevation 852 m), Chamoli district of Uttarakhand. The drainage pattern is predominantly dendritic in the study area. The morphotectonic indices are measured to know the tectonic activity of th [...]

by Floris Taminiau  and Bob van der Zwaan

Received: 04 August 2022;  Published: 10 October 2022;  doi: 10.21926/jept.2204032

In the Netherlands, an important way to contribute toward achieving climate goals is the large-scale deployment of wind turbines in the North Sea. The North Sea is a unique location for offshore wind power thanks to its strong winds, shallow waters, and proximity to large energy users. Wind turbines generate electricity by extracting kinetic energy from the atmosphere. This kinetic energy is replenished at a finite rate through the mixing of atmospheric layers. The replenishment rate sets a physical limit to the am [...]

by Patricia Lynn Dobkin

Received: 14 May 2019;  Published: 07 August 2019;  doi: 10.21926/obm.icm.1903050

The author writes a genuine story using a narrative medicine writing style [1]. She relates how she applied mindfulness awareness and meditation practices to accompany her best friend, Abigail (Abigail is a pseudonym), who struggled through stages 3 and 4 breast cancer, including its noxious treatments and upsetting side effects. Clinical practice can be enhanced with narrative competence in that it helps the author recognize, interpret and be touched by patients’ stories, including all aspects of illness experienc [...]

by Valérie Morin-Alain  , Eddy Larouche  , Anne-Marie Chouinard  , Marie-Claude Audet  , Sonia Goulet  , Louis-Simon Rousseau  and Carol Hudon

Received: 23 November 2019;  Published: 17 April 2020;  doi: 10.21926/obm.icm.2002022

Peripheral inflammation plays an important role in the pathophysiology of Alzheimer’s disease (AD) and dysregulations in circulating levels of different inflammatory mediators are detectable as early as the mild cognitive impairment (MCI) stage towards AD. Depressive symptoms, another risk factor of AD, are often found in individuals with MCI and associated with heightened levels of peripheral inflammatory mediators. Diminution in depressive symptoms and alterations of peripheral inflammation profiles have been obs [...]

by Timothy Rossow  , Elysa J Marco  , Molly Gerdes  and Teresa Tavassoli

Received: 28 July 2021;  Published: 25 October 2021;  doi: 10.21926/obm.neurobiol.2104110

Children with neurodevelopmental conditions (NDC) often have sensory reactivity differences, such as being overwhelmed by sounds, which can elicit distress in their everyday life. Furthermore, children with an NDC often present with a greater frequency of mental health symptoms compared to their typically developing peers. However little research has examined the relationship of these sensory reactivity differences on broader mental health. This study set out to explore the relationship between sensory reactivity a [...]

by Rakesh Chandra Nainwal  , Premchand Chaurasiya  , Arun Kumar  , Mohan Singh  , Devendra Singh  and Shri Krishna Tewari

Received: 14 March 2024;  Published: 12 June 2024;  doi: 10.21926/aeer.2402015

Soil salinization is a significantconstraint affecting the productivity of agricultural land worldwide. This led to the abandoning of the production of farmcrops on colossalland. Soil salinity inversely affects seed germination and plant growth and influences the plant’s biological activities like photosynthesis, respiration, plant metabolism, enzymatic activities, hormone regulation, etc. Therefore, efforts are being made to bring the saline soil under cultivation by improving itthrough a proper drainage sys [...]

by Alina Khan  , Tengfei Wan  , Catherine Hunter  , Pavel Schweizer  , Abbas Ishaq  , Shobha Nagarathanam  , Julia Morris  , Minyu Chan  and Gabriele Saretzki

Received: 13 March 2019;  Published: 01 August 2019;  doi: 10.21926/obm.neurobiol.1903036

Background: Parkinson's disease (PD) is the second most common neurodegenerative disease and is a synucleinopathy due to the critical role of α-synuclein (α-Syn) in its pathology. α-Syn is able to translocate from the cytoplasm to the nucleus and cause DNA damage. Methods: SH-SY5Y cells were stably transfected with plasmids containing wild type (WT) α-Syn and A53T mutant α-Syn as fusion proteins with EGFP and an EGFP only control vector. The cells were differentiated using retinoi [...]

by Niccolò Castellani Nicolini  , Jacopo Belfiore  and Giandomenico Biancofiore

Received: 14 May 2023;  Published: 13 October 2023;  doi: 10.21926/obm.transplant.2304198

Liver transplantation (LT) is a life-saving treatment representing the only viable option for patients suffering from end-stage liver disease (ESLD) or acute liver failure. Patients who undergo LT require a multidisciplinary approach to postoperative pain management. However, pain management in this context is often inadequately explored. Limited options exist for proper pain control in patients with hepatic failure, mainly due to the increased risk of kidney and multi-organ failure. In LT candidates, specific anal [...]

by Gerhard Litscher

Received: 11 November 2020;  Published: 13 November 2020;  doi: 10.21926/obm.icm.2004043

The Nogier reflex or reflex auriculo-cardiac (RAC) or the dynamic pulse reaction is a physiological phenomenon that is not generally accepted in conventional medicine. Therefore, evidence-based research in this sub-area is important for auricular medicine as it provides appropriate scientific evidence for better acceptance. In this editorial, a RAC measurement based on a modified smartphone registration and analysis is presented. The contribution is intended to stimulate researchers to continue working in this inte [...]

by Ahalapitiya H Jayatissa  , Omer Ahmed  , Bodhi R Manu  and Adam M Schroeder

Received: 13 August 2020;  Published: 22 January 2021;  doi: 10.21926/rpm.2101003

The tribological properties of ZnO thin film coated on an aluminium work piece by RF magnetron sputtering were studied as a function of deposition power, substrate coating temperature, heat treatment and rotation speed. The variation in the coefficient of friction of ZnO films produced under various levels of coating parameters and conditions were experimentally determined using a pin-on-disk tribometer. The results showed that with change in deposition conditions and heat treatment, there are significant microstru [...]

by Chunhui Xie  , Lillian Ye  , Yeh-Chuin Poh  and George Harb

Received: 06 May 2019;  Published: 17 July 2019;  doi: 10.21926/obm.transplant.1903072

Single cell genomics is a powerful tool to study cellular heterogeneity and discover novel cell types. Recent studies used single cell RNA sequencing (scRNA-seq) to analyze the transcriptomes of individual pancreatic islet cells. Islets are a complex mixture of endocrine cells and therefore represent an ideal tissue type for single cell transcriptomic analysis. Adult human islets consist of five known endocrine cell types (α, β, δ, γ, ε) and multiple less well-defined non-endocrine cells. In this review, we discuss [...]