by Amer Belal  , Shawna Lord  , Rohan V. Mehta  and Alfonso Santos

Received: 28 October 2022;  Published: 19 April 2023;  doi: 10.21926/obm.transplant.2302182

Cryptococcosis is a common invasive fungal infection in solid organ transplant recipients (SOTR) that can be challenging to manage. We discuss a case of disseminated cryptococcosis in a transplant recipient. A 26-year-old woman with a history of ESRD from C1q nephropathy, living-related kidney transplant in early 2012, and allograft nephrectomy in 2015, received a deceased donor kidney transplant (DDKT). Induction after the first transplant was anti-thymocyte globulin (ATG) and maintenance immunosuppression (IS) in [...]

by Stephan John  , Svenja Rink  , Leandra Weidemann  , Katrin Huesker  and Wilhelm Niedermeier

Received: 21 April 2022;  Published: 15 June 2022;  doi: 10.21926/rpm.2202012

Combining dental ceramics with other prosthetic metallic restorations might release metal ions, thus affecting the oral tissues of the patients. In this study, we evaluated the electrochemical solubility of various dental ceramics in a galvanic experimental setup in vitro. Smooth and rough feldspathic and zirconium dioxide ceramics (at pH 5.5 and pH 3.0) were exposed to an electric field. Calcium, barium, and zirconium were selected as parameters to determine the solubility of both types of ceramic materials. Among [...]

by Sally Rose  and David Sheffield

Received: 05 August 2022;  Published: 22 December 2022;  doi: 10.21926/obm.icm.2204055

This article examines the practice of combining explorations of regulated and dysregulated states through the Workable Ranges Model (WRM) with the skills and qualities taught in Mindfulness-Based Stress Reduction (MBSR). MBSR was designed to help participants to self-regulate stress. Didactic teaching about stress reactivity is part of the curriculum and may contribute to positive outcomes. A practice-based embodied methodology utilised mindful inquiry in research methods. Seven graduates of MBSR courses that inclu [...]

by Natali Lioubashevski  , Netzer Daie  , Yoram Finkelstein  and Eliezer Witztum

Received: 25 May 2023;  Published: 20 October 2023;  doi: 10.21926/obm.icm.2304043

A therapeutic intervention combines guided imagery and hypnotic techniques (including self-hypnosis), direct and indirect suggestions, medical treatments, and highly improving patient condition. A variety of hypnotic intervention techniques were introduced to treat a highly hypnotizable patient suffering from an advanced organic brain disorder due to an autoimmune disease and resistant to traditional medicine, showing no improvement despite being highly motivated and cooperating with conventional measures. Progress [...]

by A. Guillermo Bracamonte

Received: 28 July 2023;  Published: 15 November 2023;  doi: 10.21926/rpm.2304034

This mini-review discussed the best-known chemical and synthetic methodologies used in the last years to modify carbon allotropes, with an interest in nanotechnology. In this perspective, chemistry with optoelectronics applications and recent trends within bio-applications focusing mainly on graphene and its derivatives were considered. So, the mini-review intended to focus on methodologies to add functional groups with varied reactivities, polymer chemistry, and nanoscale control. These methodologies provide insig [...]

by Shih-Ang Hsu

Received: 13 December 2020;  Published: 06 July 2021;  doi: 10.21926/jept.2103031

In September 2020 Hurricane Sally affected the north central Gulf of Mexico. Making use of the anemometers data available at 4 oil rigs over the affected region, it is found that, when the atmospheric stability was near-neutral, the gust factor (G) decreases linearly with height from approximately 1.28 at 35m above the sea surface to 1.18 at 160 m. In other words, G decreases linearly at the rate around 8% per 100 m from the typical hub height to beyond common hub height. Based on the linear equation found in this [...]

by Michael Chapman  , Jennifer Philip  and Paul Komesaroff

Received: 20 December 2018;  Published: 17 June 2019;  doi: 10.21926/obm.geriatr.1902056

Alzheimer’s Disease is increasingly seen as the major health problem in developed countries supplanting cancer and heart disease. The terror with which we respond to dementia, is grounded in a view of dementia as a monstrous descent, ambushing our healthy ageing through an incursion of pathology. The pervasiveness of this view can mean that other perspectives and even the views of those most touched by the challenges of dementia remain unheard. Part of the cultural conversation around dementia is informed by [...]

by Inês Pessanha  , Catarina Cunha  , Cláudia Piedade  , Emanuel Furtado  and Maria Francelina Lopes

Received: 09 August 2020;  Published: 05 January 2021;  doi: 10.21926/obm.transplant.2101131

Diaphragmatic Hernia (DH) after Liver Transplantation (LT) is a rare complication with unclear pathophysiology. Among 261 LT, we recognized six DH during the post transplant period (2.30%). All patients with DH had received a left lateral segment (LLS) reduced graft. The mean graft weight was 340g with a mean graft-to-recipient body weight ratio (GBWR) of 4.20%. LLS grafts, a GBWR > 4%, previous abdominal surgery and direct trauma during surgery can be enumerated as potential risk factors for DH post-LT. These chil [...]

by Qin Xu  , Kang Nai  and Valery Melnikov

Received: 05 August 2022;  Published: 13 October 2022;  doi: 10.21926/jept.2204034

By using long pulses with extended dwelling time, lowered pulse repetition frequency (PRF) and reduced Nyquist velocity, the radar measurement capability can be enhanced to increase clear-air Doppler velocity data coverage (which is beneficial for radar wind analysis and data assimilation and motivated our previous study). This potential capability is further explored (beyond our previous study) by not only modifying the existing operational clear-air scan mode with a lowered PRF and reduced the Nyquist velocity (t [...]

by Elizabeth Midlarsky

Received: 14 August 2019;  Published: 25 November 2019;  doi: 10.21926/obm.geriatr.1904088

Louise H., Ph.D was referred to me by her long-term primary care physician (PCP) who was certain that his patient was seriously depressed and in need of medication and possibly psychotherapy. My own assessment, in consultation with a neurologist, was that Louise’s problems with coping were primarily neurological, and that her issues were due to serious (and in one case embarrassing) symptoms. Her neurological problems (mild Parkinsonism and PseudoBulbar Affect, or PBA) are currently being addressed by the neurologi [...]

by Joni Indah Sari  , Nydia Rena Benita Sihombing  , Nani Maharani  , Tri Indah Winarni  and Agustini Utari

Received: 30 December 2024;  Published: 14 February 2025;  doi: 10.21926/obm.genet.2501285

DiGeorge syndrome (DGS) or 22q11.2 deletion syndrome (22q11.2DS) is the most common genetic microdeletion in humans, with an incidence rate of 1:3000 to 6000 live births. Early detection and diagnosis of DiGeorge syndrome are challenging to clinicians due to its phenotype variability. We report two cases of DiGeorge syndrome, each demonstrating a different combination of clinical phenotypes. Two girls (2 years-3 months old and 2 years-2 months old) were diagnosed with 22q11.2DS following chromosomal microarray anal [...]

by Ines Testoni  , Lorenza Palazzo  , Sara Pompele  , Ciro De Vincenzo  , Maria Perardi  and Lucia Ronconi

Received: 13 November 2022;  Published: 31 March 2023;  doi: 10.21926/obm.neurobiol.2301165

Amyotrophic Lateral Sclerosis (ALS) is a progressive neurodegenerative disease that affects motor neurons, the nerve cells in the brain and the spinal cord that enable voluntary muscle movement. Managing ALS is complex and increasingly requires informal care, most often by the patient's companions/spouses or children. The COVID-19 pandemic posed additional critical issues, particularly the disruption of home care and the increased time caregivers spent on patient care. One aim of this research was to assess caregiv [...]

by Joana Sousa

Received: 10 March 2022;  Published: 24 August 2022;  doi: 10.21926/rpm.2203015

Exposure to indoor pollutants may exert a significant effect on children health as they spend most of their time in enclosed environments. This research compared the association of biological concentrations with indoor characteristics and building materials in places where children spend significant time indoors. It was compared the results of two autonomous research projects conducted in Porto primary schools and households. Both the projects included a walkthrough inspection and biological measurements in indoor [...]

by Swaraj Mohanty  , Soumya Lipsa Rath  , Poornima Sharma  and Yasmin Ahmad

Received: 11 January 2023;  Published: 04 July 2023;  doi: 10.21926/obm.genet.2303186

The outbreak of coronavirus disease-2019 (COVID-19) had a striking impact on the worldwide healthcare system within a very short period. The availability of a large number of clinical data on SARS-CoV-2, conventional precautionary majors, and treatment strategies with the existing therapeutic antiviral drug molecules also fails to control progression and disease transmission among the population. Hence, we implemented pharmacoinformatics approaches to facilitate the drug discovery by repurposing naturally available [...]

by Faten Dhawi

Received: 20 February 2024;  Published: 20 May 2024;  doi: 10.21926/obm.genet.2402235

Pearl millet (Pennisetum glaucum), a vital cereal crop renowned for its drought tolerance, is a cornerstone for smallholder farmers in arid and semi-arid regions, ranking as the fifth most significant cereal globally. Despite its resilience, the molecular mechanisms underlying its tolerance to heat stress remained elusive. To address this knowledge gap, we subjected ten-day-old pearl millet seedlings to an unprecedented temperature of 50°C for 60 seconds. Subsequent next-generation RNA sequencing aimed to unrav [...]

by Rail M. Shamionov  , Marina V. Grigoryeva  , Elena S. Grinina  , Aleksey V. Sozonnik  and Alina S. Bolshakova

Received: 13 November 2022;  Published: 09 January 2023;  doi: 10.21926/obm.neurobiol.2301150

Students' academic adaptation during the pandemic is the key problem for the educational system. Even though certain success has been achieved in the organization of education with distance learning technologies and additional learning tools, there are still plenty of other difficulties that affect students' adaptation. The purpose of the study is to conduct a comparative analysis of academic adaptation's structure during and before the pandemic and to study the role of subjective assessments of the pandemic situat [...]

by Daniel Goyal  , Fatma Mansab  , James Neil  and Jaleel Miyan

Received: 05 March 2019;  Published: 28 June 2019;  doi: 10.21926/obm.neurobiol.1902031

Background: Research into the effects of microflora on health and in disease has increased recently. Such enthusiasm seems well placed. Should the preliminary studies translate through the larger, more powerful studies, the medical community may well have an entirely new platform from which to intervene for health and against disease. Methods: Delineating the pathways involved in the microflora and host interaction is likely to yield further avenues for intervention. Here we examine autonomic function and correlate [...]

by Joep Geraedts

Received: 13 April 2017;  Published: 26 April 2017;  doi: 10.21926/obm.genet.1702003

Mark Stoneking, who is a member of the Editorial Board of OBM Genetics has written a textbook on molecular anthropology

by Jessica Walls  , Charlotte V. Farewell  , Kara Traikoff  , Haley Burns  , Joanne Whalen  , Meredith Shefferman  and Jenn A. Leiferman

Received: 31 May 2022;  Published: 26 August 2022;  doi: 10.21926/obm.icm.2203038

Many women experience depression and/or anxiety during pregnancy and/or the postpartum period. Mind-Body Interventions (MBIs) have shown great efficacy in the mitigation of these symptoms; however, there is limited research spanning the postpartum period and exploring long-term sustainability of mindfulness practice. Furthermore, little is known about specific facilitators that contribute to sustainability. The primary objective of this mixed-methods study is to use the Theory of Planned Behavior (TPB) framework to [...]

by Philip Brown  , Dana Buelsing Sowards  , Mary Pittman  , Gisele Leger  and Susan DeSipio Manns

Received: 27 February 2023;  Published: 25 May 2023;  doi: 10.21926/obm.geriatr.2302237

In August 2022, the Centers for Medicare and Medicaid Services (CMS) adopted its first-ever nutrition electronic clinical quality measure (eCQM), known as the Global Malnutrition Composite Score (GMCS) as part of the Inpatient Hospital Quality Reporting (IQR) Program. Starting in January 2024, hospitals can self-select to include the GMCS as one of three optional eCQMs for reporting. This article focuses on the importance of addressing malnutrition to improve the overall health of the aging population, reduce preve [...]

by Beren Crim Sabuncu  , Wenyi Li  and Amy L. Ai

Received: 03 November 2022;  Published: 06 April 2023;  doi: 10.21926/obm.icm.2302017

There has been a paucity in the literature on the protective effects of spiritual and social support as it pertains to trauma symptoms following a disaster. This secondary analysis investigated: a) the longitudinal analysis of the effect of perceived spiritual support (PSS; measured using PSSS-S2) on posttraumatic stress symptoms (PTSS); and b) the effect of social support and Wave-1 PTSS results on Wave-2 PTSS among Hurricane-Katrina (H-K) volunteers. We hypothesized that, 1. The shortform PSSS-S2 would have an ad [...]

by Abdel Zaro  , Spencer Jones  and Ethan Languri

Received: 31 August 2023;  Published: 16 November 2023;  doi: 10.21926/jept.2304035

In this paper, an efficient industrial wastewater and leachate evaporation method is proposed and tested experimentally. The goal of this study is to investigate whether the addition of a carbon foam (CF) porous layer can lead to energy savings by evaporating more water mass per unit of energy input. The standard boiling evaporator layout was redesigned by placing the heating element in the upper region of the tank and CF underneath the heat source. The CF purposed to localize the energy in an area by the water' [...]

by Gerald Jandl  , Rainer Horn  , Richard Schroeder  , Kai-Uwe Eckhardt  and Peter Leinweber

Received: 23 November 2022;  Published: 22 March 2023;  doi: 10.21926/jept.2301012

The increasing number of biogas plants with various digested organic materials and output of digestates calls for more detailed investigations of their suitability as soil amendments. In a trial in Northern Germany two replicate plots each were treated with fresh or prolonged fermented digestate to investigate the influence of digestates on the composition of soil organic matter (SOM). The relative proportions of relevant SOM compound classes were determined by pyrolysis-field ionization mass spectrometry (Py-FIMS) [...]

by George Z. Voyiadjis  and Peter I. Kattan

Received: 27 October 2020;  Published: 10 May 2021;  doi: 10.21926/jept.2102021

A robust mathematical method for the characterization of damage in carbon nanotubes is presented the presentation here is limited to elasticity. In this regard, the second and third order elastic stiffnesses are employed. All this is based on damage mechanics. The hypotheses of elastic strain equivalence and elastic energy equivalence are utilized. A new damage variable is proposed that is defined in terms of the surface area. This is in contrast to the classical damage variable which is defined in terms of the cro [...]

by Paul Fagan

Received: 10 August 2022;  Published: 16 February 2023;  doi: 10.21926/aeer.2301021

Focusing upon the United Kingdom reveals that centralised provisions of energy have historically failed to uphold standards of human rights. Even if a transition is made to renewable energy, existing centralised distribution systems cannot promise improvement. This work would recommend the transition to domestic renewables, whereby energy is harnessed and used in situ, as it may support the more desirable notion of social justice with regard to energy usage. Domestic renewables are likely to become an inevitability [...]