Table of Content

Open Access Original Research

3D Printed Polylactic Acid (PLA) Well Plates for Enzyme Inhibition Studies: The Case of Pancreatic Lipase

Received: 31 July 2022;  Published: 08 October 2022;  doi: 10.21926/cr.2204032

Abstract

3D printed PLA has already been demonstrated for several biotechnological applications, including enzymes immobilization. The prerequisites for an efficient screening assay include using small volumes of reagents, low cost, and rapid screening of large numbers of compounds and extracts. Hence, assays based on microtiter plates are predominant. Thus, designing and fabricating scaffolds on a similar scale, which could serve as immobilization carriers, and their recruitment in inhibitors screening studies is of great [...]

1528 9219

Open Access Original Research

Experimental Phenomenology as Personalized Health Intervention: A Case Illustration

Received: 27 July 2021;  Published: 15 February 2022;  doi: 10.21926/obm.icm.2201008

Abstract

Experimental phenomenology is the investigation of phenomenological practices and their effects. To engage in a phenomenological practice means to focus attention on aspects of one’s experiences (e.g., sense impressions or body sensations) while adopting a specific kind of attitude (e.g., an explorative attitude) according to some set of instructions. The basic assumption is that the regulation of attention and attitudes involved in such practices may have effects on people’s health and quality of life. The present [...]

1142 9217

Open Access Original Research

Heterologous Expression, Characterization, and Comparison of Laccases from the White Rot Causing Basidiomycete Cerrena Unicolor

Received: 26 July 2022;  Published: 20 September 2022;  doi: 10.21926/cr.2203028

Abstract

Lignin is the most abundant renewable source of aromatics on earth, and conversion of it to chemicals and fuels is needed to build an economically viable renewable biofuels industry. Biological routes to converting lignin to fuels and chemicals involve depolymerizing lignin using lignin-degrading enzymes that catalyze the breaking of ether and carbon-carbon bonds in the phenolic and non-phenolic subunits of lignin. Laccases are a crucial class of lignin-degrading enzymes and are copper-containing enzymes capable of [...]

1590 9216

Open Access Original Research

Fischer-Tropsch Synthesis on Co/SBA-15 Catalyst: Characterization and Oligomerization Modeling

Received: 05 May 2022;  Published: 16 August 2022;  doi: 10.21926/cr.2203023

Abstract

In this study, we investigated the oligomerization mechanism of the Fischer-Tropsch synthesis catalyzed by a cobalt-based catalyst supported by SBA-15. The Co/SBA-15 catalyst contained 20% w/w of cobalt. It was prepared by the wet impregnation method and characterized by X-ray diffraction (XRD), N2 adsorption-desorption, temperature-programmed reduction (TPR), and scanning electron microscopy coupled to X-ray energy dispersion spectroscopy (SEM-EDS). The FT synthesis was conducted in a slurry bed reactor operating [...]

1836 9214

Open Access Original Research

Resilience and Burnout among Medical Students: The Role of Difficulties with Emotion Regulation as A Mediator

Received: 06 March 2023;  Published: 19 September 2023;  doi: 10.21926/obm.icm.2303038

Abstract

Burnout is a chronic state of exhaustion caused by prolonged stress. Medical training has been shown to leave many medical students vulnerable to burnout, which can negatively impact their health and patient care. While resilience has been associated with lower burnout, the mechanisms through which resilience reduces burnout are not well established. Therefore, this study aimed to investigate whether difficulties with emotion regulation mediate the relationship between resilience and burnout among medical students. [...]

1492 9210

Open Access Original Research

Generalized Resistance Resources in the Time of COVID-19: The Role of Sense of Coherence and Resilience in the Relationship between COVID-19 Fear and Loneliness among Schoolteachers

Received: 30 April 2022;  Published: 15 August 2022;  doi: 10.21926/obm.neurobiol.2203130

Abstract

Fear has been the most common emotional response to the COVID-19 pandemic, and excessive fear is associated with various indices of psychological distress, particularly loneliness. Although most people have experienced pandemic-related fear and distress, certain groups who are on the front of service provision have experienced the pandemic in distinct ways, owing to its impact on the nature of their work. Schoolteachers represent one such group; therefore, it is imperative to identify resources that can safeguard a [...]

1540 9202

Open Access Research Article

Teachers’ Perceptions of Integrating Tower Gardens into Pre-K4 Curriculum

Received: 31 August 2023;  Published: 17 January 2024;  doi: 10.21926/rpn.2401002

Abstract

Schools play an integral role in providing opportunities for children of all ages to be exposed to nutrition education. There are a variety of ways children can receive nutrition education in the school setting, such as explicit lessons, modeled dialogue, and exposure to nutrition-based principles. However, there continues to be a disconnect between teacher perceptions of nutrition education and time spent implementing it in the classroom. Nutrition education can come in many forms, including hands-on gardening and [...]

1652 9194

Open Access Original Research

Dental Services Utilization by over 65 Years Old in Israel in 2020

Received: 01 May 2022;  Published: 17 November 2022;  doi: 10.21926/obm.geriatr.2204212

Abstract

To understand dental service utilization in the over-65 age group and to identify the main patterns and barriers to uptake of dental care after the 2019 expansion under the National Health Insurance Law to include dental benefits for the over-75 age group. Phone interviews with a random sample of 512 people over the age of 65 were conducted between February and April 2020. About half had visited a dentist during the previous year (an average of 2.9 visits) while 17% reported they had never visited one. Dental servi [...]

1360 9191

Open Access Case Report

Changes in SPECT Brain Imaging in Pediatric Patients with Suspected Neuroborreliosis: A Series of 6 Cases

Received: 01 April 2019;  Published: 14 May 2019;  doi: 10.21926/obm.neurobiol.1902028

Abstract

Lyme disease is a spirochetal illness transmitted primarily through the bite of ticks. The disease has a broad spectrum of comorbid conditions including osteoarticular, cardiovascular, and neurological involvement. In addition, clinical variability depends on the age of affected individuals. The Center for Disease Control recognizes the disease as an epidemic and mentions it to be a major morbidity burden in our environment because of the frequent lack of diagnosis and early treatment. Scientific literature mention [...]

1400 9189

Open Access Original Research

Associations between Health-Related Behaviours, Well-Being, and Academic Performance of Secondary School Students with Special Educational Need: A Secondary Analysis

Received: 24 October 2022;  Published: 06 March 2023;  doi: 10.21926/rpn.2301005

Abstract

Health-related behaviours (HRBs) have been considered one of the most critical public health issues, especially for those with special educational needs (SEN). Previous research suggests that health-related behaviours are highly likely to impact well-being and academic achievement. Diet is a crucial health-related behaviour that needs to be investigated along with factors such as sleep and exercise. The present study used data from the Cornish Academies Project, and secondary analyses were conducted to investigate [...]

1326 9185

Open Access Review

Delaying Dementia: Targeted Brain Delivery Using Lipid Cubic Phases

Received: 22 August 2019;  Published: 16 September 2019;  doi: 10.21926/obm.neurobiol.1903040

Abstract

Microvascular endothelial dysfunction precedes, often by decades, the cognitive decline associated with Alzheimer's disease. Hence, preservation of a healthy cerebrovascular endothelium can be an important therapeutic target. By incorporating appropriate drug(s) into biomimetic (lipid cubic phase) nanocarriers, one obtains a multitasking combination therapeutic which targets certain cell-surface scavenger receptors, mainly class B type I (i.e., SR-BI), and crosses the blood-brain barrier. Documented similarities in [...]

1568 9183

Open Access Original Research

Sustainable Water Management Using Rainfall-Runoff Modelling in Rift Valley Basin, East Africa

Received: 03 September 2024;  Published: 06 January 2025;  doi: 10.21926/aeer.2501003

Abstract

Managing water resources offers crucial information about the availability of water supplied from catchments into water bodies, which plays a vital role in water resource engineering. However, due to changes in the global climate, hydrological modeling of river catchments is critically crucial for socio-economic development and livelihoods. Numerous models evaluate runoff from precipitation, but the SCS-CN method is fundamental and the most widely recognized for calculating runoff. This research evaluates runoff de [...]

1197 9181

Open Access Review

Epstein-Barr Virus and Helicobacter pylori as Two Main Risk Factors in Gastric Cancer

Received: 21 June 2024;  Published: 20 November 2024;  doi: 10.21926/obm.genet.2404272

Abstract

Microbial and viral pathogens have emerged as key contributors to cancer development. Research conducted in the last twenty years has significantly enhanced our comprehension of the cancer-causing capabilities of infectious agents. An illustrative instance is gastric cancer (GC), which is closely associated with Helicobacter pylori (H. pylori) and Epstein-Barr virus (EBV) infections, with approximately 90% of non-cardia GC cases attributed to H. pylori infection and around 10% linked to EBV. Despite significant res [...]

1677 9175

Open Access Short Report

Walk with Me

Received: 14 May 2019;  Published: 07 August 2019;  doi: 10.21926/obm.icm.1903050

Abstract

The author writes a genuine story using a narrative medicine writing style [1]. She relates how she applied mindfulness awareness and meditation practices to accompany her best friend, Abigail (Abigail is a pseudonym), who struggled through stages 3 and 4 breast cancer, including its noxious treatments and upsetting side effects. Clinical practice can be enhanced with narrative competence in that it helps the author recognize, interpret and be touched by patients’ stories, including all aspects of illness experienc [...]

1944 9175

Open Access Original Research

Influence of Recycled Concrete Aggregate Type on Rheological Behaviour of Mixtures Proportioned Using the Equivalent Volume Method

Received: 11 July 2022;  Published: 07 September 2022;  doi: 10.21926/rpm.2203017

Abstract

The ever-growing urgency to combat climate change has led the civil construction industry to develop and adopt sustainable construction materials and methods. The so-called recycled concrete aggregate (RCA) emerges as an alternative to decrease the carbon footprint of new concrete construction, the disposal of waste concrete, and the use of non-renewable natural resources such as cement and aggregates. RCA can be produced from crushing waste concrete; yet challenges remain when using RCA in concrete especially its [...]

1384 9172

Open Access Review

FISHing for Unstable Cellular Genomes in the Human Brain

Received: 06 February 2019;  Published: 30 April 2019;  doi: 10.21926/obm.genet.1902076

Abstract

The human brain has been repeatedly shown to exhibit intercellular/somatic genomic variations at the chromosomal level, which are involved in the neuronal diversity in health and disease. Brain-specific chromosomal mosaicism (aneuploidy) and chromosome instability play a role in the normal and pathological neurodevelopment, neurodegeneration and aging of the central nervous system. Regardless of achievements in somatic cell (single-cell) genomics, there is still no consensus on the amounts of chromosomally abnormal [...]

1760 9171

Open Access Original Research

Comparative Analysis of the Relationship between Renewable Energy Adoption, Fossil Fuel Energy Consumption, and CO2 Emission in the United States and China

Received: 11 March 2024;  Published: 26 September 2024;  doi: 10.21926/aeer.2403018

Abstract

This study addresses the critical issue of carbon dioxide (CO2) emissions, focusing on understanding the intricate interplay between four major variables Gross Domestic Product per capita (GDPC), Renewal Energy (RE), Fossil Fuel energy consumption (FF), and Patent application (PTS). This research is crucial due to the emerging negative impacts of climate change, which will create a disastrous future for human beings. It focuses on three decades from 1990 to 2020 and compares the results between the United States an [...]

820 9170

Open Access Research Article

Testing the Correlation between Prior Knowledge of - and Visualisation Guided WTPs for Reducing the Visual Impacts Visual from Offshore Wind Farms

Received: 28 April 2020;  Published: 12 August 2020;  doi: 10.21926/jept.2003015

Abstract

Visual external costs are significant elements in the cost-benefit analysis of wind farm locations. This has been demonstrated well in the literature. However, in the assessment of the visual costs, a large share of the earlier studies used no or only simplistic visualizations of the visual impacts at stake. The cost estimates thus rely on the respondents’ ability to imagine the visual impacts associated with wind turbines of different sizes and at different locations. This has been argued to potentially reduce the [...]

1968 9163

Open Access Original Research

Misinterpretation or Underestimation of the Appearance, Location, or Size of Non-bleeding Visible Vessels (Forrest Class IIa) as a Cause of Hemostasis Failure

Received: 10 December 2017;  Published: 14 March 2018;  doi: 10.21926/obm.hg.1801006

Abstract

(1) Background: Endoscopy has become the primary diagnostic and treatment technique for non-variceal upper gastrointestinal bleeding. Despite advancements in therapeutic methods and instrumentation, endoscopic hemostatic failure occurs in 10% of patients. This study aimed to analyze endoscopic findings in patients with failed hemostasis and to elucidate strategies for endoscopists and gastroenterologists to facilitate improved treatment outcomes. (2) Methods: A total of 128 patients received hemostatic treatment fo [...]

1376 9160

Open Access Research Article

Restoration of Reservoir Caprock: Long-Term Wellbore Sealing and Abandonment through Zeolite Enhanced Cement

Received: 21 March 2022;  Published: 29 April 2022;  doi: 10.21926/aeer.2202017

Abstract

Oil and gas wellbores that are drilled into the earth’s crust need to be plugged and abandoned, to restore the geological seals once they are no longer producing. The main aim of Plugging and abandonment (P&A) is to ensure that there is no leakage of hydrocarbons into the environment. Since offshore P&A is challenging due to subsurface temperature and pressure conditions, testing zeolite as an additive for improvement of cement properties is an intriguing research topic. This initial research aims to [...]

1370 9158

Open Access Review

Molecular Plant Physiology for Model Plants under Abiotic Stress Conditions

Received: 23 December 2023;  Published: 24 April 2024;  doi: 10.21926/obm.genet.2402230

Abstract

Extreme temperatures, drought, and high soil salinity are some of the significant abiotic stresses that can severely impact crop yields, posing a threat to global food production. Comprehensive studies on model plant species are crucial for understanding their biochemical, physiological, and molecular responses to abiotic stresses. Identifying stress response mechanisms and potential targets can aid in developing stress-tolerant crop varieties. Additionally, elucidating the functions of reactive oxygen species is e [...]

1337 9158

Open Access Original Research

Dearomatization of the Kerosene Fraction: Kinetic Studies

Received: 09 January 2022;  Published: 28 June 2022;  doi: 10.21926/cr.2202017

Abstract

The kinetics of dearomatization of a kerosene fraction processed using a zeolite catalyst (0.9 HZSM-5) at different temperatures (160-200°C), the molar ratio between the aromatic hydrocarbons present in the kerosene fraction and n-decene (1:(0.5-4)), and the reaction time (1-3 h) were studied. Based on the obtained data, a kinetic model for kerosene dearomatization is proposed. It is assumed that the single-center Riedel mechanism is followed. The stage associated with the interaction between n-decene adsorbed on t [...]

1599 9156

Open Access Original Research

Single-Center Outcomes of Heart Transplantation in Patients with Pulmonary Hypertension Bridged with Mechanical Circulatory Support

Received: 14 April 2020;  Published: 06 July 2020;  doi: 10.21926/obm.transplant.2003114

Abstract

In advanced heart failure, orthotopic heart transplantation (OHT) remains the standard for definitive treatment. Patients with heart failure and concomitant pulmonary hypertension (PH) represent a challenging subgroup, with poor outcomes following OHT. Recently, Mechanical Circulatory Support (MCS) devices have been utilized as a bridge to OHT for these patients. Patients with MCS devices who underwent OHT were evaluated at a single center. Patients were stratified into three groups, depending on baseline pulmonary [...]

1659 9156

Open Access Review

Islet Autotransplantations for Total Pancreatectomy

Received: 15 January 2019;  Published: 03 April 2019;  doi: 10.21926/obm.transplant.1902059

Abstract

Total pancreatectomy (TP) is performed for not only malignant pancreatic diseases but also benign disease such as chronic pancreatitis or pancreatic injury. However, because this surgery involves removal of the whole pancreas, both exocrine and endocrine pancreatic functions are abolished, significantly impairing the nutritional statuses of patients as well as having other detrimental outcomes. Thus, especially in benign cases additional treatment to recover endocrine function is recommended, as permanent endocrine [...]

1218 9151

Open Access Review

Do Antioxidants Extend Longevity in Invertebrate and Vertebrate Animals?

Received: 09 November 2022;  Published: 07 March 2023;  doi: 10.21926/obm.geriatr.2301226

Abstract

In the 1950’s Denham Harman proposed the Free Radical Theory of Aging whereby species lifespan and individual longevities are the consequence of free radical driven damage to biomolecules. This led to decades of research to ascertain the effect of altered antioxidant defense systems on aging and mortality in an array of species using reverse genetics and dietary manipulation. Within invertebrates, the data generally support the Free Radical Theory in that overexpression of antioxidant enzymes or dietary supplementa [...]

1301 9143

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