Table of Content

Open Access Interview

An Interview with Dr. Pietro Gareri

Received: 02 July 2025;  Published: 02 July 2025;  doi: 10.21926/obm.geriatr.2503318

657 2535

Open Access Research Article

Technology Support to Enable People with Severe Intellectual Disability and Blindness to Carry Out Occupational Activities and Transition Between Them Independently

Received: 14 July 2025;  Published: 09 October 2025;  doi: 10.21926/obm.neurobiol.2504303

Abstract

People with severe intellectual disability and blindness tend to perform only simple occupational activities and are mostly unable to transition between those activities. This inability makes their level of occupation independent of staff support fairly limited. Technology-aided programs may be one of the few opportunities available to increase their independent occupation. This study assessed one such program designed to (a) monitor the participants’ responses and guide them to transition to a new activity once th [...]

612 2522

Open Access Original Research

Cultural Distance, Host Acculturation Orientation, and Psychological Adaptation among African International Students at Portuguese Universities

Received: 10 July 2025;  Published: 24 October 2025;  doi: 10.21926/obm.icm.2504045

Abstract

International students represent a significant sojourner group. Increasing international student numbers makes it ever more relevant to understand the determinants of their psychological adaptation. This research investigates the question of how perceived cultural distance (PCD) impacts acculturation variables (social contact with host nationals and host national identity) and outcomes such as saudade and life satisfaction among African international students. The sample comprised 422 college students (195 from Ang [...]

503 2447

Open Access Review

Contribution of Solar Energy to Buildings’ Energy Demands: A Review

Received: 27 June 2025;  Published: 12 January 2026;  doi: 10.21926/aeer.2601002

Abstract

Buildings account for a significant portion of global energy consumption, estimated at 30-40%, and also contribute to greenhouse gas emissions. Energy consumption in a building is mainly thermal (natural gas) and electrical. This energy is usually used for heating water, cooking, illumination, ventilation and air conditioning, powering appliances, floor heating, and other activities. These activities were examined, and their substitution by solar-based energy sources was reviewed. To achieve this objective, an exte [...]

826 2432

Open Access Original Research

Immunologic Response after COVID-19 Vaccination in Heart Transplant Recipients

Received: 30 June 2025;  Published: 21 October 2025;  doi: 10.21926/obm.transplant.2504259

Abstract

To date, all large-scale randomized controlled trials for COVID-19 vaccines have excluded solid organ transplant recipients; therefore, the effectiveness and safety of COVID-19 vaccines in preventing coronavirus infection using COVID-19 vaccines in patients with heart transplants have not been sufficiently studied. This paper presents the characteristics of humoral and cellular immunity in heart transplant recipients following vaccination against coronavirus infection. The study group consisted of 40 patients who u [...]

567 2421

Open Access Editorial

Acknowledgement to Reviewers of OBM Geriatrics in 2024

Received: 02 January 2025;  Published: 02 January 2025;  doi: 10.21926/obm.geriatr.2501293

Abstract

The editors of OBM Geriatrics would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2024. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal’s editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers can download a certificate of recognition directly from our submission system. Additionally, reviewers can sign up to the Web of S [...]

513 2386

Open Access Original Research

Effects of Trauma, Shame, and Self-Criticism on Hoarding: Comparative Data and Treatment Implications

Received: 31 January 2025;  Published: 01 December 2025;  doi: 10.21926/obm.icm.2504051

Abstract

Severe trauma has a significant impact on self-attitudes and emotions, such as self-criticism and shame, and psychological symptoms. This topic has been more well studied among populations with Trauma and Stress-Related Disorders, but examined to a lesser extent in other clinical populations where adverse life events and potentially traumatic events are highly prevalent, such as Hoarding Disorder. The current study examined trauma exposure, and the relationships between trauma, self-criticism, shame, and symptom se [...]

752 2362

Open Access Perspective

From Vision to Strategy: Expanding Metaversal Integrative Healthcare with DAOs and Blockchain Ecosystems

Received: 26 May 2025;  Published: 26 November 2025;  doi: 10.21926/obm.icm.2504050

Abstract

Legacy, profit-driven organizational structures often lack the adaptability, equity, and innovation required for the evolving complexities of contemporary patient-centered care. They can limit access, constrain options, impose financial burdens, and hinder optimized delivery. Here, we propose a new architecture for metaversal integrative healthcare using decentralized autonomous organizations (DAOs). Blockchain technology and smart contracts underpin equitable, transparent, and resilient health ecosystems beyond in [...]

467 2360

Open Access Review

Exposure to Mycotoxins: Neurological Disorders and Psychiatric Manifestations

Received: 27 October 2025;  Published: 09 February 2026;  doi: 10.21926/obm.neurobiol.2601322

Abstract

Mycotoxins, toxic secondary metabolites produced by fungi and molds, have negative health impacts on both humans and animals. They are commonly found in foods such as nuts, coffee, cereals, and grains, particularly in regions with warm, humid climates. Among the most prevalent mycotoxins in these foods are aflatoxin B1, ochratoxin A, zearalenone, patulin, and deoxynivalenol (DON). The presence of mold capable of producing mycotoxins within food contributes to an elevated risk of various illnesses, including those r [...]

915 2334

Open Access Research Article

Investigating Mental Health Literacy and Its Relationship with Addiction to Social Networks among Allied Medical Sciences Students

Received: 24 June 2025;  Published: 19 November 2025;  doi: 10.21926/obm.neurobiol.2504311

Abstract

The widespread use of social media among college students has become a significant concern due to its potential impact on mental health and addictive behaviors. Social media platforms, while offering numerous benefits, can also foster environments that contribute to addiction, depression, and anxiety. College students, in particular, are vulnerable to these effects due to their high levels of social media engagement and the pressures of academic life. Mental health literacy, which involves understanding and managin [...]

553 2333

Open Access Research Article

Sleep and Mood as Mechanisms Linking Trauma Exposure to Alcohol Use in South African First Responders: A Serial Mediation Analysis

Received: 15 June 2025;  Published: 14 November 2025;  doi: 10.21926/obm.neurobiol.2504308

Abstract

First responders are routinely exposed to traumatic events in the line of duty, placing them at heightened risk for adverse mental health outcomes, including substance use. This study investigated the psychological mechanisms linking trauma exposure to alcohol use, specifically examining the serial mediating roles of insomnia and depression. A sample of 429 first responders (309 police officers and 120 paramedics) from the Western Cape, South Africa, completed an online survey comprising the Life Events Checklist-5 [...]

568 2329

Open Access Interview

An Interview with Prof. Rosita Gabbianelli

Received: 24 August 2025;  Published: 27 August 2025;  doi: 10.21926/rpn.2503017

Abstract

An Interview with Prof. Rosita Gabbianelli

490 2308

Open Access Original Research

Evaluation of Full Blood Count–Derived Inflammatory Indices (SII, SIRI, PIV, NLR) in Behçet’s Disease Patients and Healthy Controls

Received: 01 October 2025;  Published: 24 November 2025;  doi: 10.21926/obm.genet.2504318

Abstract

This study investigated three novel complete blood count–derived inflammatory biomarkers Systemic Immune-Inflammation Index (SII), Systemic Inflammation Response Index (SIRI), and Pan-Immune-Inflammation Value (PIV) and their relationship with clinical features of Behçet’s Disease (BD). Established markers, including neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and monocyte-to-lymphocyte ratio (MLR), were also analyzed. Seventy HLA-B51–positive BD patients and 114 HLA-B51–negative healt [...]

525 2278

Open Access Original Research

Environmental Risk Assessment of Antiretrovirals Consumed in Belo Horizonte, Brazil

Received: 09 June 2025;  Published: 04 December 2025;  doi: 10.21926/aeer.2504034

Abstract

The development and utilization of pharmaceuticals, notably antiretrovirals (ARVs), have significantly enhanced both human quality of life and life expectancy. Nevertheless, the excretion of these compounds into aquatic environments, often exacerbated by inadequate sanitation infrastructure, poses considerable risks to biota. This investigation evaluated the environmental impact of 14 ARVs consumed within the municipality of Belo Horizonte (BH), Brazil. The assessment employed the Environmental Risk Assessment (ERA [...]

709 2275

Open Access Original Research

When the Psychological Weight of the Burden Affects the Physical Weight of Caregivers of Older Patients in a French Memory Hospital (Lille, France)

Received: 23 May 2025;  Published: 10 October 2025;  doi: 10.21926/obm.geriatr.2504328

Abstract

Caring for patients with neurocognitive disorders (NCD) can be challenging for caregivers, with the risk of malnutrition. Observational, retrospective, monocentric study carried out with patient-caregiver dyads admitted to the Memory Day Hospital of the Gerontology Center of the University Hospital of Lille over 6 months in 2023. Our objectives were to identify the socio-characteristics of caregivers who had recently experienced a variation in their weight, their degree of fatigue (using the Fatigue Numerical Ratin [...]

642 2240

Open Access Original Research

Mindful Attention and Awareness Prospectively Predicts Stress in Daily Life: A Multilevel Modeling Approach

Received: 17 June 2025;  Published: 09 October 2025;  doi: 10.21926/obm.icm.2504042

Abstract

Chronic stress increases a person’s vulnerability for physical and mental health conditions that take root in the “common soil” of inflammation. Dispositional, or trait, mindfulness has been identified as a protective factor against perceived stress. However, the theory that trait mindfulness can prospectively predict lower perceived stress in natural settings has yet to be thoroughly tested. The current study used a daily diary prospective design to observe perceived stress in response to difficult events. Partici [...]

492 2188

Open Access Original Research

Barriers Encountered When Implementing a Community Evidence-Based Fall Prevention Program

Received: 11 June 2025;  Published: 05 November 2025;  doi: 10.21926/obm.geriatr.2504330

Abstract

Falls and fall-related injuries are one of the leading causes of death among older adults aged 65+ in the United States. Americans’ life expectancy has increased and fall risk grows with age. While several evidence-based fall prevention programs are utilized to decrease fall risk among community-dwelling older adults, little research focuses on challenges or strategies related to sustained fall prevention program implementation. The purpose of this multi-method descriptive study was to assess fall risk outcome chan [...]

580 2143

Open Access Original Research

GHG Emissions Management in Urban Areas by Interactive Road Traffic Control: Application of Artificial Intelligence

Received: 04 June 2025;  Published: 03 December 2025;  doi: 10.21926/aeer.2504033

Abstract

The rising pollution levels in congested urban areas pose a serious threat to human health. Many solutions have been proposed to control and reduce gas emissions from road traffic, with results that are not entirely satisfactory. The adoption of new techniques and methodologies for early detection of pollutant emissions may enable effective management and control of road traffic contamination. The proposed method introduces an interactive protocol that facilitates communication between the traffic control center an [...]

572 2127

Open Access Original Research

Rapid Green Synthesis of Silver Nanoparticles and Alginate-Silver Nanocomposite Beads Using Mashmoom (Ocimum basilicum), a Bahraini Household Medicinal Herb

Received: 16 June 2025;  Published: 17 November 2025;  doi: 10.21926/rpm.2504017

Abstract

The study focuses on the rapid green synthesis of silver nanoparticles (AgNPs) and alginate-silver nanocomposite (Alg-AgNc) beads using sweet basil or Mashmoom (Ocimum basilicum), a common household medicinal herb in Bahrain. The aqueous extract of mashmoom was used as a reducing and stabilizing agent in the reduction of the precursor salt, silver nitrate, and formation of stable AgNPs. The Alg-AgNc beads were prepared by ionotropic gelation of sodium alginate-AgNPs solution in calcium chloride. A strong surface pl [...]

593 2061

Open Access Original Research

Framework for the Secured Integration of Renewable Energy into Power Systems

Received: 11 June 2025;  Published: 05 December 2025;  doi: 10.21926/jept.2504016

Abstract

This research introduces a blockchain framework to improve security and transparency for the use of renewable energy in power systems. The framework utilizes a permissioned blockchain architecture and IoT-based real-time monitoring to ensure data integrity and confidentiality and support efficient peer-to-peer (P2P) energy trading. Compared with traditional centralized energy management systems, the proposed design increases transaction security by 35%, decreases verification wait times by 28%, and decreases the ri [...]

587 2048

Open Access Commentary

Targeting Neuroinflammation in Difficult-to-Treat Depression: From Anti-Inflammatory Agents to Multi-Target Immunopsychiatric Interventions

Received: 30 July 2025;  Published: 27 January 2026;  doi: 10.21926/obm.neurobiol.2601321

Abstract

Difficult-to-treat depression (DTD) with inflammatory features (e.g., hs-CRP ≥3 mg/L and/or elevated IL-6) may represent a clinically and biologically distinct presentation characterized by chronicity, functional impairment, prominent cognitive-motivational symptoms, and suboptimal response to conventional treatments. Classical anti-inflammatory strategies (e.g., COX-2 inhibitors or cytokine-targeting biologics) have shown signals of efficacy in selected biomarker-enriched subgroups; however, overall evidence remai [...]

695 2046

Open Access Original Research

A Frequency Analysis of the Professional Quality of Life of NeuroAffective Relational Model (NARM) Therapists after NARM Training

Received: 25 July 2025;  Published: 04 January 2026;  doi: 10.21926/obm.icm.2601001

Abstract

Research shows that trauma therapists often experience secondary trauma, which can lead to secondary traumatic stress, compassion fatigue, and burnout. Trauma-informed care training has shown promise in enhancing practitioners' professional quality of life, particularly for those regularly exposed to trauma. To our knowledge, no prior studies have examined the training outcomes of NeuroAffective Relational Model (NARM) therapists on professional quality-of-life indicators. This cross-sectional observational study a [...]

519 2015

Open Access Original Research

Differential Expression of MiR-21 and MiR-19 in Biliary Atresia: Diagnostic Potential and Therapeutic Implications

Received: 24 May 2025;  Published: 26 November 2025;  doi: 10.21926/obm.genet.2504319

Abstract

Biliary atresia (BA), a severe pediatric liver disease of unknown etiology, causes neonatal jaundice, progressive cholestasis, and life-threatening liver fibrosis. Emerging evidence suggests microRNAs (miRNAs) – small non-coding RNAs that regulate gene expression by binding target mRNAs may play a role in BA pathogenesis. Circulating miRNAs have shown diagnostic potential for various diseases, prompting our investigation of miR-21 and miR-19 as potential biomarkers in BA. We conducted a case-control study comparing [...]

678 1991

Open Access Original Research

Genetic Differentiation of Populations of Three Megalopolises by DNA Markers of the Y-Chromosome in Connection with the Problem of Developing Genetic Databases

Received: 04 June 2025;  Published: 12 January 2026;  doi: 10.21926/obm.genet.2601324

Abstract

The purpose of the study was to consider the distribution of Y-chromosome DNA markers in samples from the populations of the three largest megalopolises (Moscow, Saint Petersburg, and Novosibirsk) in the Russian Federation, in the context of developing genetic databases. The study aimed to compare the frequency profiles of 18 Y-chromosome STRs (Short tandem repeats) and the level of genetic differentiation. Based on FST estimates for the distribution of these 18 Y-chromosome STRs, the senior generations of Moscow a [...]

579 1967

Open Access Review

Risk Assessment in Clinical Histocompatibility Testing: Challenges, Strategies, and Future Directions

Received: 15 July 2025;  Published: 25 November 2025;  doi: 10.21926/obm.transplant.2504260

Abstract

Though the role of clinical histocompatibility testing is fundamental to successful transplant, systematic risk assessment and mitigation strategies remain underutilised in this domain. This review addresses risk identification, analysis, and control measures across the pre-analytical, analytical, and post-analytical phases of clinical histocompatibility testing, in line with international standards such as ISO 15189:2022. A structured, risk-based quality management system (QMS) is imperative for ensuring accurate [...]

572 1966

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