by Daniel Szoke  and Holly Hazlett-Stevens

Received: 17 June 2025;  Published: 09 October 2025;  doi: 10.21926/obm.icm.2504042

Chronic stress increases a person’s vulnerability for physical and mental health conditions that take root in the “common soil” of inflammation. Dispositional, or trait, mindfulness has been identified as a protective factor against perceived stress. However, the theory that trait mindfulness can prospectively predict lower perceived stress in natural settings has yet to be thoroughly tested. The current study used a daily diary prospective design to observe perceived stress in response to difficult events. Partici [...]

by Vikash Chandra Mishra  , Dinesh Chandra  and Vimarsh Raina

Received: 15 July 2025;  Published: 25 November 2025;  doi: 10.21926/obm.transplant.2504260

Though the role of clinical histocompatibility testing is fundamental to successful transplant, systematic risk assessment and mitigation strategies remain underutilised in this domain. This review addresses risk identification, analysis, and control measures across the pre-analytical, analytical, and post-analytical phases of clinical histocompatibility testing, in line with international standards such as ISO 15189:2022. A structured, risk-based quality management system (QMS) is imperative for ensuring accurate [...]

by Brandi M. Crowe  , Karen Kemper  and Marieke Van Puymbroeck

Received: 11 June 2025;  Published: 05 November 2025;  doi: 10.21926/obm.geriatr.2504330

Falls and fall-related injuries are one of the leading causes of death among older adults aged 65+ in the United States. Americans’ life expectancy has increased and fall risk grows with age. While several evidence-based fall prevention programs are utilized to decrease fall risk among community-dwelling older adults, little research focuses on challenges or strategies related to sustained fall prevention program implementation. The purpose of this multi-method descriptive study was to assess fall risk outcome chan [...]

by Jozélio Freire de Carvalho  and Rosangela Passos de Jesus

Received: 27 October 2025;  Published: 13 February 2026;  doi: 10.21926/rpn.2601002

Selenium (Se) is a key micronutrient integrated into selenoproteins such as glutathione peroxidases (GPx), which are responsible for crucial antioxidant and anti-inflammatory mechanisms. Oxidative stress contributes to the immunopathogenesis and chronic joint damage of rheumatoid arthritis (RA), supporting interest in selenium supplementation as an adjunct therapeutic strategy. This review was based on a structured literature search of major biomedical databases and evaluated six controlled clinical trials involvin [...]

by Jude Alhaddad  , Hawra Alkhadad  , Fatima AlHannan  , Fryad Henari  and G. Roshan Deen

Received: 16 June 2025;  Published: 17 November 2025;  doi: 10.21926/rpm.2504017

The study focuses on the rapid green synthesis of silver nanoparticles (AgNPs) and alginate-silver nanocomposite (Alg-AgNc) beads using sweet basil or Mashmoom (Ocimum basilicum), a common household medicinal herb in Bahrain. The aqueous extract of mashmoom was used as a reducing and stabilizing agent in the reduction of the precursor salt, silver nitrate, and formation of stable AgNPs. The Alg-AgNc beads were prepared by ionotropic gelation of sodium alginate-AgNPs solution in calcium chloride. A strong surface pl [...]

by Oteja Lightheart  and Helané Wahbeh

Received: 09 August 2025;  Published: 07 January 2026;  doi: 10.21926/obm.icm.2601004

Older adults in the U.S. have higher rates of depression, stress, and chronic diseases. There is an urgent need for effective interventions to reduce depressive symptoms and enhance overall health and well-being. Meditation presents an appealing therapeutic option due to its cost-effectiveness, minimal risks, ease of use, and active patient involvement, with growing evidence indicating its effectiveness in reducing depressive symptoms. Online platforms may provide more accessible options for meditation intervention [...]

by Ferydoon Khamooshi  , Samaneh Doraji-Bonjar  , Ali Reza Modarresi-Alam  and Mohammad Hasan Mohammadi

Received: 03 May 2025;  Published: 04 January 2026;  doi: 10.21926/obm.neurobiol.2601318

The study explores the crucial biological function of nitrogen in cyclic and acyclic structures with resonance potential, including tetrazoles, pyrroles, piperidines, and carbamates, within the realm of chemical neuroscience. It highlights the importance of these compounds for their biological properties and their ability to cross the blood-brain barrier (BBB) to reach the central nervous system (CNS). The study emphasizes the necessity for neurochemical drugs, like morphine, to effectively cross the BBB, as modifi [...]

by Adel Razek

Received: 07 October 2025;  Published: 17 December 2025;  doi: 10.21926/rpse.2504017

A relevant objective of managing an electromagnetic (EM) device is to improve its expected results and reduce its undesirable side effects. In this context, this paper aims to evaluate the interest of the two One Health and Responsible Attitude methods in the daily practice of wireless transmission (or transfer) in EM energy devices. These approaches are respectively linked to device eco-design and optimization, as well as to the protection of biodiversity and ecosystems against device side effects related to EM fi [...]

by Ami Rokach

Received: 24 August 2025;  Published: 25 November 2025;  doi: 10.21926/obm.neurobiol.2504312

A significant social stigma is associated with loneliness. The prevalence of social isolation, in the dawn of the 21st century points to the growing isolation in America. Lonely people who commonly display negative self-perceptions, show great difficulty to establish social ties, and that may be related to their personal inadequacies, or socially undesirable attributes. Lonely people suffer from a low social perception, painting them as less psychologically adjusted, and not very capable in relating to others. That [...]

by Divya Mobarsa  , Kedar Mehta  , Amit Sata  and Minal Shukla

Received: 11 June 2025;  Published: 05 December 2025;  doi: 10.21926/jept.2504016

This research introduces a blockchain framework to improve security and transparency for the use of renewable energy in power systems. The framework utilizes a permissioned blockchain architecture and IoT-based real-time monitoring to ensure data integrity and confidentiality and support efficient peer-to-peer (P2P) energy trading. Compared with traditional centralized energy management systems, the proposed design increases transaction security by 35%, decreases verification wait times by 28%, and decreases the ri [...]

by Konstantinos Agiannitopoulos  and Elisavet Kouvidi

Received: 02 May 2025;  Published: 25 December 2025;  doi: 10.21926/obm.genet.2504321

Leukemia is a heterogeneous group of hematologic malignancies characterized by the dysfunctional proliferation of white blood cells in the bone marrow. Genetic alterations are important risk factors for the development and progression of leukemia, and their detection is crucial. Although many genetic techniques, including karyotyping, fluorescence in situ hybridization (FISH), and polymerase chain reaction (PCR), have provided valuable information, they all have the limitation of incomplete genomic coverage. The ev [...]

by Emeka H. Amalu  and Justice O. Nwaneto

Received: 26 June 2025;  Published: 13 February 2026;  doi: 10.21926/jept.2601003

As the demand for cleaner-greener energy surges owing to more nations adopting Net Zero Emission by 2050, wind turbine (WT) technology is increasingly poised as one of the technologies to match the demand. Capacity building in the development of cost-effective WT tower with improved reliability and safety has become critical to delivering Net Zero mandate. This research demonstrates implementation of Taguchi Design of Experiment (DoE) in conjunction with Signal-to-noise ratio (S/N) to optimise both structural desig [...]

by Hanuman Singh Jatav

Received: 21 December 2025;  Published: 24 December 2025;  doi: 10.21926/aeer.2504035

The rising concerns of soil erosion, organic waste generation and global warming have shown the need to address them through multifaceted methods that transcend conventional linear models of resource utilization. Circular economy is a regenerative model that is anchored on caring about waste valorisation, resource effectiveness and environmental fortitude. In this paradigm, biochar has been developed as a multifunctional compound capable of integrating waste management, soil rehabilitation, climate control and rene [...]

by Manal Hadi Ghaffoori Kanaan  , Beom-Jin Lee  , Sura Saad Abdullah  , Chulhun Park  , Abdolmajid Ghasemian  and Steward Mudenda

Received: 10 October 2025;  Published: 14 January 2026;  doi: 10.21926/obm.genet.2601325

Stem cell-derived exosomes (SDEs) have emerged as revolutionary mediators in cancer immunotherapy, offering unprecedented potential to reprogram the immunosuppressive tumor immune microenvironment (TIME). These nano-sized extracellular vesicles, laden with non-coding RNAs (ncRNAs), serve as natural biocompatible carriers, capable of orchestrating immune cell dynamics, stromal remodeling, and tumor cell fate. Unlike their tumor-derived counterparts, which often propagate oncogenic signals, SDEs uniquely harbor immun [...]

by Mahintaj Dara  , Negar Azarpira  , Nasrin Motazedian  , Mahdokht Hossein-Aghdaie  , Seyed-Mohsen Dehghani  , Bita Geramizadeh  and Elaheh Esfandiari

Received: 24 May 2025;  Published: 26 November 2025;  doi: 10.21926/obm.genet.2504319

Biliary atresia (BA), a severe pediatric liver disease of unknown etiology, causes neonatal jaundice, progressive cholestasis, and life-threatening liver fibrosis. Emerging evidence suggests microRNAs (miRNAs) – small non-coding RNAs that regulate gene expression by binding target mRNAs may play a role in BA pathogenesis. Circulating miRNAs have shown diagnostic potential for various diseases, prompting our investigation of miR-21 and miR-19 as potential biomarkers in BA. We conducted a case-control study comparing [...]

by Rustam Nailevich Mustafin

Received: 17 August 2025;  Published: 08 December 2025;  doi: 10.21926/obm.neurobiol.2504314

Schizophrenia is a multifactorial mental disorder associated with multiple SNPs in the human genome, located mainly outside the annotated protein-coding genes. These regions contain a large number of retroelements, which drive epigenetic regulation. Therefore, it is suggested that schizophrenia-associated SNPs exert their influence on the pathological functioning and activation of retroelements, which contribute to epigenetic imbalance in the brain with the development of pathological processes. A reflection of the [...]

by Chawannuch Ruaengsri  , Miguel Alvarez-Cortes  , Marc Leon  , Manuel Quiroz-Flores  , Masafumi Shibata  and Yasuhiro Shudo

Received: 30 June 2025;  Published: 30 December 2025;  doi: 10.21926/obm.transplant.2504261

Donation after circulatory death (DCD) offers a vital strategy to expand the donor lung pool; however, DCD lungs are uniquely susceptible to warm ischemic injury during procurement. This chapter reviews evidence-based and emerging donor management strategies aimed at mitigating ischemic damage and optimizing the suitability of DCD lungs for transplantation, encompassing hemodynamic and ventilatory optimization, bronchoscopic clearance, targeted pharmacological interventions, and strategies to minimize transfusion r [...]

by G.-Fivos Sargentis  , Sofian Baroudi  , Marios-Athanasios Angelidis  , Ilias Arvanitidis  , Nikos Mamassis  and Romanos Ioannidis

Received: 03 November 2025;  Published: 01 March 2026;  doi: 10.21926/aeer.2601005

Mediterranean regions like West Mani, Greece, face escalating water scarcity exacerbated by climate variability and seasonal tourism peaks, straining the water-energy-food (WEF) nexus. Olive cultivation, central to the region’s economy and culture, generates substantial underutilized biomass residues that increase wildfire risk if left unmanaged. At the same time, water supply increasingly relies on energy-intensive desalination and pumping. This study addresses the gap in integrated, place-based WEF nexus applicat [...]

by Chuan-Tsung Lee

Received: 15 September 2025;  Published: 10 December 2025;  doi: 10.21926/jept.2504017

Taiwan relies heavily on imported fossil fuels, with over 98% of its energy demand supplied by foreign sources, posing significant challenges to national energy security. To explore alternatives, this study investigates the potential of marine renewable energy by developing a 20 kW floating hydrokinetic turbine prototype designed for deployment in the Kuroshio Current. The research encompasses system design, model validation, and both tank and at-sea testing to evaluate hydrodynamic performance and power generation [...]

by Ola A. E. Mohamed  and Ibtisam E. M. El Zubeir

Received: 30 July 2025;  Published: 22 December 2025;  doi: 10.21926/rpn.2504026

This study was conducted to process frozen yoghurt (FY) from camel milk (CM) flavored with either 5% or 8% banana (B) or dates (D). The mix of FY consists of stirred yoghurt, sugar, Gum Arabic, and banana (Musa lutea) or dates (Phoenix dactylifera). The mix was divided into 4 portions and then each mix was sub-derived into an ice-cream machine and then packed into plastic cups that were stored at -18°C for 5 weeks. The chemical composition and sensory evaluation were conducted weekly. The chemical composition of FY [...]

by Norbert Maurer  , Helmut Nissel  , Reginald Bittner  , Richard Crevenna  , Marion Mucha  , Erich Gornik  and Georg Feigl

Received: 11 November 2024;  Published: 09 November 2025;  doi: 10.21926/obm.icm.2504048

Morphological evidence of peripheral glial cell involvement is lacking. Therefore, we investigated the presence of Schwann cells in acupuncture meridians. Eight legs of four unembalmed cadavers were used. Along the stomach meridian and a control meridian, quadrangular samples were taken from skin to the deep subcutaneous fascia and embedded in paraffin. 5 µm sections were stained for H&E and processed for immunolabeling using antibodies against S100 and NFP, respectively. In the stomach meridian, a large assembly o [...]

by Muhammad Uzair Riaz  and Cornelia Breitkopf

Received: 14 January 2026;  Published: 09 March 2026;  doi: 10.21926/rpse.2601003

Effective thermal management in polymeric materials still represents a considerable challenge for emerging applications, such as wearable electronics, soft robotics, and sustainable composite systems, wherein flexibility and environmental compatibility are of utmost importance. This research utilizes non-equilibrium molecular dynamics (NEMD) simulations to examine interfacial thermal resistance (ITR) and effective thermal conductivity (keff) in bio-based PBS-ENR-PBS trilayer systems. Two varieties of epoxidized nat [...]

by Giulio E. Lancioni  , Gloria Alberti  , Chiara Filippini  , Nirbhay N. Singh  , Mark F. O’Reilly  and Jeff Sigafoos

Received: 18 August 2025;  Published: 27 November 2025;  doi: 10.21926/obm.neurobiol.2504313

Recent work with people with blindness and intellectual disability assessed a technology-aided program intended to help eight participants travel indoor routes to reach relevant destinations. The technology included a smartphone, two barcode readers worn by the participants at their ankles, barcodes displayed at specific points of the travel routes, and a mini speaker. The technology ensured that participants received verbal instructions on how to proceed (e.g., take a left turn, cross from one side to the other of [...]

by Walid Mohamed Mahmud

Received: 09 September 2024;  Published: 26 March 2026;  doi: 10.21926/jept.2601006

Electrical submersible pumps (ESPs) are an efficient and reliable artificial lift method for lifting large volumes of fluids from wellbores at flexible rates. Despite their advantages, including high flow rates and real-time downhole telemetry, ESPs are prone to frequent and unforeseen failures under harsh reservoir conditions, resulting in costly production delays and interventions. This paper presents an integrated evaluation of ESP failure mechanisms based on an analysis of run and pull reports, dismantle inspec [...]

by Katherine Lucre  , Fatema Bhalloo  , Louis Brown  and Angela Foster

Received: 13 October 2025;  Published: 13 February 2026;  doi: 10.21926/obm.icm.2601009

It has become increasingly evident that individuals who work in the NHS can be heavily impacted by the nature of their work; for instance, PTSD, work related burnout, vicarious trauma, moral injury, anxiety, and depression. In turn, individuals who experience said psychological difficulties often require work-related mental health leave from work. This paper examines the experience of a One-day Compassionate Mind Training workshop (CMT), available for all NHS staff. This day has an emphasis on developing multidirec [...]