by Recent Progress in Science and Engineering Editorial Office

Received: 19 March 2025;  Published: 19 March 2025;  doi: 10.21926/rpse.2501004

by Filomena Emanuela Laddaga  , Tommasina Perrone  , Pellegrino Musto  , Ilaria Farella  , Stefano Martinotti  and Francesco Gaudio

Received: 22 February 2025;  Published: 18 June 2025;  doi: 10.21926/obm.transplant.2502253

Primary mediastinal large B-cell lymphoma (PMLBCL) is an aggressive B-cell malignancy that may exhibit resistance to standard chemoimmunotherapy. Novel immunotherapeutic strategies, including checkpoint inhibitors and chimeric antigen receptor T-cell (CAR-T) therapy, are being explored in cases that are refractory to treatment. We report the case of a 29-year-old patient with refractory PMLBCL who was treated with pembrolizumab as a bridging therapy followed by axicabtagene ciloleucel (CAR-T) after failing R-CHOP a [...]

by Ziyad Alharbi

Received: 27 March 2024;  Published: 13 January 2025;  doi: 10.21926/obm.transplant.2501231

The supraclavicular artery flap presents a promising solution for facial reconstruction challenges since 1997, surpassing limitations of traditional methods like the deltopectoral flap. Its extended pedicle and thin, pliable epidermis offer reliable outcomes with minimal donor site morbidity, making it a preferred choice for head and neck reconstruction. This systematic review evaluates the efficacy of pre-expanded supraclavicular artery flaps based on a comprehensive analysis. In accordance with the Preferred Repo [...]

by Advances in Environmental and Engineering Research Editorial Office

Received: 03 January 2024;  Published: 04 January 2024;  doi: 10.21926/aeer.2401001

The editors of Advances in Environmental and Engineering Research would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2023. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers can download a certificate of recognition directly from our submission system. Additionall [...]

by Paul Gilbert  , Derek Griner  , Kelly Morter  , Ptarmigan Plowright  , Jaskaran Basran  , Hannah Gilbert  , Victoria Nithsdale  , Eva Rogers  , Yoram Giglio  and Corinne Gale

Received: 07 April 2025;  Published: 12 January 2026;  doi: 10.21926/obm.icm.2601005

There is now good evidence for the efficacy of Compassion Focused Therapy (CFT) for a variety of mental health difficulties. To deepen understanding of the processes underpinning CFT’s effectiveness, this service evaluation explored the experiences and reflections of individuals with long-term mental health difficulties who had previously received therapy and attended an 11-week CFT group. Ten clients were invited to the group; one withdrew before the group started because of work and personal commitments and anoth [...]

by Yasmin Cherni  , Ridha Elleuch  , Cristian Botta  , Luca Cocolin  , Amjed Kallal  , Ismail Trabelsi  and Lobna Elleuch

Received: 09 November 2023;  Published: 16 September 2025;  doi: 10.21926/rpm.2503014

The sustainable management of water resources is increasingly recognized as a critical component of environmental conservation and socio-economic development. Among the most challenging aspects of wastewater treatment is the effective remediation of landfill leachate, a complex and highly polluted effluent characterized by high levels of organic matter, ammonia, turbidity, and heavy metals. This study investigates an integrated treatment approach that combines chemical coagulation using aluminum sulfate with a subs [...]

by Hardiyati Hardiyati  , Iyus Yosep  , Meita Dhamayanti  , Veranita Pandia  and Rohman Hikmat

Received: 17 May 2025;  Published: 15 September 2025;  doi: 10.21926/obm.neurobiol.2503301

This article aims to evaluate the impact of mindfulness training on Mr. A, a 17-year-old adolescent with schizophrenia experiencing social isolation and severe anxiety. The subject, Mr. A, is a 17-year-old male who presented with significant anxiety symptoms, including excessive worry, restlessness, difficulty concentrating, irritability, heart palpitations, rapid breathing, and sleep disturbances. These symptoms were accompanied by behaviors of social withdrawal, emotional detachment, and reluctance to communicate [...]

by Garzain Bint e Attar  and Mohd. Ashif Khan

Received: 15 May 2025;  Published: 31 December 2025;  doi: 10.21926/obm.transplant.2504262

Bone grafting remains a cornerstone technique in orthopedic and reconstructive surgery, yet achieving successful graft integration continues to pose significant challenges, particularly in conditions such as osteoporosis, diabetes mellitus, and large bone defects. Traditional graft materials such as autografts, allografts, xenografts, and synthetics, often encounter limitations including immune rejection, poor vascularization, and insufficient osteogenic support. Emerging pharmacological strategies have shown promi [...]

by Pamela Whitaker

Received: 11 May 2025;  Published: 28 July 2025;  doi: 10.21926/obm.icm.2503033

Performance art is both a visual arts practice and kinaesthetic approach to place-based health. The perspective of this commentary is to promote the attributes of performance art to showcase its capacity to extend people into new configurations of cultural engagement with beneficial effects. Performance art is an opportunity to engage both mind and body in actions that transform predictability and encourage wellness within the context of people’s life studios (their everyday lives). Wellness is defined here in rela [...]

by OBM Geriatrics Editorial Office

Received: 03 January 2024;  Published: 04 January 2024;  doi: 10.21926/obm.geriatr.2401265

The editors of OBM Geriatrics would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2023. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal’s editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers can download a certificate of recognition directly from our submission system. Additionally, reviewers can sign up to the We [...]

by Chuk Ling Julian Lai  , Wei Yin  and Jianwei Shi

Received: 20 July 2024;  Published: 02 March 2025;  doi: 10.21926/obm.geriatr.2501300

Based on a framework derived from theories of social integration and health, this study examined the relationships between motivation to cultivate social ties or network cultivation, and diurnal salivary cortisol in Chinese older adults. The main objective was to determine the behavioral mechanism that translated a higher motivation to cultivate social ties into healthier diurnal cortisol rhythms in 82 community-dwelling elders in Shanghai. Participants were provided four saliva samples immediately, 30 minutes, and [...]

by Yongjeong Kim  , Saera Kwak  and Taejin Koh

Received: 28 April 2025;  Published: 09 October 2025;  doi: 10.21926/obm.neurobiol.2504304

This study examines how university students perceive Learning Management System (LMS)-based instruction within the context of higher education, as they adapt to the rapid digital transformation. Specifically, it examines how students' perceptions differ based on gender and academic achievement, providing insights for more inclusive and adaptive instructional design. LMS platforms, when actively utilized, offer more than just content delivery—they can enhance classroom transparency, provide immediate feedback, promo [...]

by David Cawthorpe

Received: 04 March 2025;  Published: 11 September 2025;  doi: 10.21926/obm.icm.2503038

This paper presents a unifying transcultural perspective on human illness, health and wellbeing by integrating insights from cognitive psychology, existential psychotherapy, Zen philosophy, Traditional Chinese Medicine (TCM), and quantum consciousness theory. Kahneman and Tversky’s work on heuristics and biases highlights cognitive constraints shaping decision-making, while Yalom’s existential therapy explores fundamental struggles with death, freedom, and meaning. Watts’ Zen philosophy critiques the illusion of eg [...]

by Birgit M. Jürgenhake  and Leo M. Oorschot

Received: 23 March 2025;  Published: 19 November 2025;  doi: 10.21926/obm.geriatr.2504331

This article explores the ongoing work associated with the masterclasses "Towards an Inclusive Living Environment." It critically examines the concept of healthy living for all and aging in place by studying neighborhoods within Dutch cities. The article argues that creating inclusive, healthy environments fosters well-being and promotes a lifestyle of health and autonomy for all. Next to literature studies, we worked with our students in different neighborhoods of The Hague, conducting ethnographic research. Throu [...]

by Nadezhda G. Duplii  , Kirill V. Azarin  , Alexander V. Usatov  , Andrey A. Plotnikov  , Ritu Rani  and Vishnu D. Rajput

Received: 20 February 2025;  Published: 22 July 2025;  doi: 10.21926/obm.genet.2503305

The present work aimed to study the effects of 10-(6'-plastoquinonyl) decyltriphenylphosphonium (SkQ1) on rice (Oryza sativa) plants germinating under flooding conditions. The influence of different concentrations of SkQ1 (mitochondria-targeted antioxidant) on resistance to complete flooding was assessed on rice seedlings of the Kuboyar variety. The total level of reactive oxygen species (ROS), H2O2-induced chemiluminescence, and gene expression of antioxidant enzymes (OsSODA (superoxide dismutase A), OsSODB (s [...]

by Icih Susanti  , Noki Irawan Saputra  , Lina Budiyanti  , Aam Amalia  , Rohman Hikmat  and Iyus Yosep

Received: 11 September 2025;  Published: 17 November 2025;  doi: 10.21926/obm.neurobiol.2504309

Adolescent depression is linked to suicidal ideation and attempts. Nurses are well-positioned to deliver brief, supportive interventions. Solution-Focused Brief Therapy (SFBT) emphasizes solutions and the activation of personal resources. To describe the feasibility and clinical utility of SFBT, delivered alongside pharmacotherapy, for reducing suicide risk in an adolescent with depression. Single-case report using a nursing process approach in a 17-year-old female inpatient with a major depressive episode and high [...]

by Bachir Yaou Balarabe

Received: 24 October 2025;  Published: 03 November 2025;  doi: 10.21926/cr.2504008

by Alvard Minasyan  and Naira Sahakyan

Received: 20 May 2025;  Published: 30 July 2025;  doi: 10.21926/obm.neurobiol.2503293

Microglial activation and the associated oxidative or inflammatory responses play a crucial role in the development of neurodegenerative diseases. In this study, we evaluated the antioxidant, cytotoxic, and anti-inflammatory properties of Teucrium polium (TP) ethanolic extract in murine BV-2 microglial cells, including wild-type (Wt) and peroxisomal β-oxidation-deficient Acox1-/- cell lines. The TP extract exhibited high antioxidant activity as assessed via the DPPH test, with an IC50 value of 73.89 μ [...]

by Ivanna Shymanska  , Sofiia Levandivska  , Marharyta Marchuk  , Anastasiya Honchar  , Volodymyr Kravets  and Halyna Makukh

Received: 30 November 2024;  Published: 04 September 2025;  doi: 10.21926/obm.genet.2503309

Biallelic pathogenic variants in C1QBP are an infrequent, yet increasingly recognised, cause of progressive external ophthalmoplegia (PEO). Although most published cases include cardiomyopathy, isolated late‑onset PEO without cardiac disease remains exceptional. To characterise, for the first time, a Moldavian‑Ukrainian pedigree in which homozygous c.612C>G (p.Phe204Leu) in C1QBP causes autosomal‑recessive PEO in the absence of cardiomyopathy, thereby expanding the phenotypic spectrum of C1QBP‑related disease. W [...]

by James D Adams

Received: 09 February 2025;  Published: 10 February 2025;  doi: 10.21926/obm.icm.2501010

Medicines used in pain and chronic pain are aimed at relieving neuroinflammation. This neuroinflammation can occur in the brain, brain stem, dorsal root ganglion and other sites. What causes neuroinflammation? Why does this neuroinflammation last for years? Are there cures for neuroinflammation?

by Corrado Angelini

Received: 06 February 2024;  Published: 21 June 2024;  doi: 10.21926/obm.icm.2402035

An 83-year-old man with myasthenia gravis was hospitalized in the ICU; support for caregivers of elderly myasthenic patients in the ICU can be a crucial aspect of their care. Myasthenia gravis is a chronic autoimmune neuromuscular disease that can cause varying levels of muscle weakness, which can significantly impact the patient's day-to-day activities and overall quality of life. This intervention was followed for over one month with success. The critical phases are presented and analyzed as a medical support art [...]

by Lyubov Starodub  , Nataliia Mokhnachova  and Ostap Zhukorskyi

Received: 16 April 2025;  Published: 07 July 2025;  doi: 10.21926/obm.genet.2503302

Characterization of the non-coding part of the transcriptome is a supplement to the annotation of the genome of living organisms. According to ISSR-fingerprinting data, information is obtained about ancient gene pools, modern gene pools, genetic variability and conservation of breeds and species of farm animals. The aim of the study is to study the molecular genetic component and phylogenetic relationships in the aboriginal Hutsul horse breed and fossil remains of ancient horses using ISSR-PCR markers. The polymorp [...]

by Lúcia Bacalhau  and Patrícia Pontífice-Sousa

Received: 19 September 2024;  Published: 06 February 2025;  doi: 10.21926/obm.transplant.2501233

Allogeneic Stem Cells Transplantation (ASCT) and, consequently, the chronicity associated with this life event has a growing prevalence and a significant impact on the life and daily life of each person who experiences it. The growing number of ASCT survivors highlights the need to reflect on the unique challenges they face throughout their recovery. To understand the meaning of the encounter with time in the lived experience of comfort for survivors of ASCT. Qualitative approach using van Manen's phenomenology of [...]

by Lunawati Lo Bennett

Received: 25 August 2025;  Published: 15 October 2025;  doi: 10.21926/obm.genet.2504313

Non-small cell lung cancer (NSCLC), accounting for approximately 85% of lung cancer cases, remains a leading cause of cancer-related mortality. Genetic alteration such as EGFR mutations, tobacco exposure, and resistance to apoptosis, slows its progression and limits therapeutic success. Although targeted therapies and immunotherapy have improved outcomes for select patients, resistance remains a major challenge, highlighting the need for more effective treatments. This study investigated the potential synergistic i [...]

by Fery Lusviana Widiany  , Metty  , Rahayu Widaryanti  and Shafira Nur Azizah

Received: 01 April 2025;  Published: 19 September 2025;  doi: 10.21926/rpn.2503020

Hemodialysis patients require a diet rich in protein that is easily digestible, such as tempeh. Tempeh is a local Indonesian food product that can be purchased at a low price. Tempeh has a low sodium content, but there has never been an analysis related to the difference in sodium content in local Indonesian soybean tempeh products and imported soybean tempeh. This study was to compare the sodium analysis of different tempeh types in Indonesia as a preliminary study for the subsequent research to fulfill a high-pro [...]