Table of Content

Open Access Original Research

An Exploration of the Experiences of Group Compassion Focused Therapy for Hospital Outpatients with Long-Term Mental Health Difficulties

Received: 07 April 2025;  Published: 12 January 2026;  doi: 10.21926/obm.icm.2601005

Abstract

There is now good evidence for the efficacy of Compassion Focused Therapy (CFT) for a variety of mental health difficulties. To deepen understanding of the processes underpinning CFT’s effectiveness, this service evaluation explored the experiences and reflections of individuals with long-term mental health difficulties who had previously received therapy and attended an 11-week CFT group. Ten clients were invited to the group; one withdrew before the group started because of work and personal commitments and anoth [...]

1808 3161

Open Access Research Article

Potential Synergistic Interaction Between Curcumin and Sorafenib Enhances Cytotoxicity in NCI-H5222 Lung Cancer Cells

Received: 25 August 2025;  Published: 15 October 2025;  doi: 10.21926/obm.genet.2504313

Abstract

Non-small cell lung cancer (NSCLC), accounting for approximately 85% of lung cancer cases, remains a leading cause of cancer-related mortality. Genetic alteration such as EGFR mutations, tobacco exposure, and resistance to apoptosis, slows its progression and limits therapeutic success. Although targeted therapies and immunotherapy have improved outcomes for select patients, resistance remains a major challenge, highlighting the need for more effective treatments. This study investigated the potential synergistic i [...]

707 3159

Open Access Case Report

Netherton Syndrome in a 9-Month-Old Child: Unraveling a Complex Dermatologic Disorder

Received: 05 June 2025;  Published: 15 September 2025;  doi: 10.21926/obm.genet.2503311

Abstract

Netherton syndrome is a rare autosomal recessive disorder caused by mutations in the SPINK5 gene, leading to LEKTI protein dysfunction, impaired skin barrier function, and immune dysregulation. It manifests as a triad of ichthyosiform erythroderma, trichorrhexis invaginata (bamboo hair), and atopic diathesis, often mimicking other inflammatory dermatoses. We report a 9-month-old Javanese Indonesian male infant presenting with extensive erythematous, scaly skin lesions and severe pruritus. Laboratory tests revealed [...]

630 3117

Open Access Review

Medical Digital Technologies in Older Patients with Cardiac Disease Achievements and Drawbacks

Received: 17 February 2025;  Published: 09 September 2025;  doi: 10.21926/obm.geriatr.2503323

Abstract

Older adults are a growing population characterized by a high prevalence of multimorbidity and age-related conditions, such as organ and pharmacokinetic dysfunction. Medical digital technologies have emerged through the combined use of wearable, implantable, and insertable medical devices with digital systems. Gerontology aims to help older patients with disabilities utilize these technologies. These technologies are used in high-tech medical centers, particularly among older cardiac patients. Many cardiac societie [...]

716 3081

Open Access Original Research

Investigating Associations between Maternal Mindfulness, Mental Health, Interoception and Mother-Infant Relationship during Pregnancy and Post-Partum in a Non-Clinical Community Sample

Received: 21 May 2025;  Published: 26 October 2025;  doi: 10.21926/obm.icm.2504046

Abstract

Pregnancy and the postpartum period are times of significant transition for women, with changes in maternal physical and mental health. The relationship between a mother and her infant has been recognised as laying the foundation for later child development. There is considerable evidence that this early relationship is influenced by a woman’s wellbeing during pregnancy and in the early post-partum period. Mindfulness has been found to have positive health outcomes, primarily in reducing maternal stress, anxiety, a [...]

756 3048

Open Access Review

Pharmacological Strategies to Enhance Bone Graft Integration: Emerging Agents and Molecular Pathways

Received: 15 May 2025;  Published: 31 December 2025;  doi: 10.21926/obm.transplant.2504262

Abstract

Bone grafting remains a cornerstone technique in orthopedic and reconstructive surgery, yet achieving successful graft integration continues to pose significant challenges, particularly in conditions such as osteoporosis, diabetes mellitus, and large bone defects. Traditional graft materials such as autografts, allografts, xenografts, and synthetics, often encounter limitations including immune rejection, poor vascularization, and insufficient osteogenic support. Emerging pharmacological strategies have shown promi [...]

1350 3025

Open Access Editorial

Acknowledgment to Reviewers of Advances in Environmental and Engineering Research in 2024

Received: 02 January 2025;  Published: 02 January 2025;  doi: 10.21926/aeer.2501002

Abstract

The editors of Advances in Environmental and Engineering Research would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2024. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers can download a certificate of recognition directly from our submission system. Additionally, r [...]

543 2985

Open Access Review

Maladjustment in Minority Youth from Community Network Disparities in the COVID-19 Lockdown Environment

Received: 17 April 2024;  Published: 04 August 2025;  doi: 10.21926/obm.neurobiol.2503295

Abstract

Pandemic lockdown orders resulted in closures to critical community networks. One such infrastructure was community recreation centers/parks. This infrastructure serves a critical role in building psychosocial wellness for youth. Socioeconomic minority youth face baseline disparity in center/park distribution and services. Youth recreation activity declined 50% as result of lockdown orders with corresponding decline in youth mental health status. Despite overall youth activity decline, White and high socioeconomic [...]

558 2962

Open Access Original Research

Fabrication of CuO-Decorated Fe2O3 Nanoparticles as Efficient and Durable Electrocatalyst for Oxygen Evolution Reaction

Received: 09 August 2025;  Published: 07 November 2025;  doi: 10.21926/cr.2504009

Abstract

The electrochemical water oxidation application of CuO@Fe2O3 materials as potential catalysts is being reported for the first time. A series of CuO@Fe2O3 with different molar ratios of CuO (5, 7, 10, 12, and 15%) was fabricated through precipitation followed by the impregnation method. Structural and electrochemical studies were carried out by using different analytical platforms, including X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), Energy dispersive [...]

939 2904

Open Access Case Report

Nursing Care for a Patient with a Risk of Suicide Due to Depression Using the Solution-Focused Brief Therapy Approach: Case Study

Received: 11 September 2025;  Published: 17 November 2025;  doi: 10.21926/obm.neurobiol.2504309

Abstract

Adolescent depression is linked to suicidal ideation and attempts. Nurses are well-positioned to deliver brief, supportive interventions. Solution-Focused Brief Therapy (SFBT) emphasizes solutions and the activation of personal resources. To describe the feasibility and clinical utility of SFBT, delivered alongside pharmacotherapy, for reducing suicide risk in an adolescent with depression. Single-case report using a nursing process approach in a 17-year-old female inpatient with a major depressive episode and high [...]

487 2890

Open Access Original Research

Deep Learning Approaches for Predicting Strain Energy in Heterogeneous Materials

Received: 15 July 2025;  Published: 24 October 2025;  doi: 10.21926/rpm.2504016

Abstract

This paper investigates data-driven strain energy prediction for heterogeneous elastic materials using the Mechanical MNIST benchmark dataset (60,000 28 × 28 stiffness maps by precomputed finite-element results). The results by classical regression models (linear regression, random forest, and gradient boosting) using hand-crafted features were compared with the results by the deep learning models (Convolutional neural network (CNN) and residual network (ResNet)) trained end-to-end on images. In held-out tests, CNN [...]

771 2813

Open Access Editorial

Acknowledgment to Reviewers of OBM Genetics in 2024

Received: 03 January 2025;  Published: 03 January 2025;  doi: 10.21926/obm.genet.2501277

Abstract

The editors of OBM Genetics would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2024. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers can download a certificate of recognition directly from our submission system. Additionally, reviewers can sign up to the Web of Sci [...]

633 2791

Open Access Interview

An Interview with Prof. Dr. Roy G. Beran

Received: 27 April 2025;  Published: 28 April 2025;  doi: 10.21926/obm.geriatr.2502310

580 2756

Open Access Original Research

Network Topology Similarities Across Cancer Types: Identifying Central Protein Hubs for Drug Discovery

Received: 18 June 2025;  Published: 13 October 2025;  doi: 10.21926/obm.genet.2504312

Abstract

A molecular-level understanding of cancer is essential for the development of effective therapies. Constructing protein-protein interaction (PPI) networks offers a valuable approach to identifying dysregulated driver genes and potential therapeutic targets. In this study, we modeled cancer PPI networks as metric spaces and applied mathematical and computational algorithms to analyze their structural and functional properties. Our findings reveal that these networks share a conserved architecture across different ca [...]

666 2723

Open Access Original Research

Evaluation of the Transitional Pain Service Specialized Iyengar-Informed Yoga Program for Chronic Post-Surgical Pain: A Pilot Randomized Controlled Trial

Received: 29 April 2025;  Published: 30 September 2025;  doi: 10.21926/obm.icm.2503041

Abstract

The objective of this randomized controlled trial (RCT) was to evaluate the feasibility and efficacy of a specialized Iyengar-informed yoga intervention for individuals who experience chronic post-surgical pain (CPSP). This prospective, multi-wave pilot RCT was pre-registered at clinicaltrials.gov (NCT03460028) and designed in accordance with the 2010 CONSORT statement. Participants (N = 21) with CPSP were out-patients or community members affiliated with a Toronto hospital. Participants were randomized to an 8-wee [...]

709 2707

Open Access Original Research

The Effect of Adding Mealworm, Probiotics, and Mealworm Plus Probiotics on IL-8 Gene Expression in Liver and Spleen Tissues of Broiler Chickens

Received: 30 July 2025;  Published: 30 October 2025;  doi: 10.21926/obm.genet.2504315

Abstract

Interleukin-8 (IL-8), a pro-inflammatory cytokine, plays a critical role in immune modulation in poultry and has potential applications in veterinary and human medicine. This study investigated the effects of dietary supplementation with mealworm (Tenebrio molitor), probiotics, or their combination on IL-8 gene expression in the livers and spleens of broiler chickens. A total of 160 one-day-old broiler chickens (Ross 308 strain) were assigned to four treatments (basal diet, basal diet + 0.2 g/kg probiotic, basal di [...]

647 2703

Open Access Original Research

Occurrence of Multidrug Resistant Escherichia coli & Escherichia coli O157:H7 in Raw Cow Milk from Dhaka, Bangladesh

Received: 01 May 2025;  Published: 09 December 2025;  doi: 10.21926/rpn.2504025

Abstract

Enteropathogenic strains of Escherichia coli, like the serotype O157:H7, can cause significant health issues if consumed. Milk and dairy products can serve as a reservoir for the bacteria. Dissemination of multidrug-resistant E. coli through dairy products can become a potential health hazard if consumed. The present study investigates the occurrence of multidrug-resistant E. coli O157:H7 in raw milk obtained from farms and markets around Dhaka, Bangladesh. A Total of 50 milk samples were collected in this study fr [...]

806 2697

Open Access Interview

An Interview with Prof. Andrew S Day

Received: 24 February 2025;  Published: 25 February 2025;  doi: 10.21926/rpn.2501003

603 2687

Open Access Review

Healthy Ageing and its Communal Nemesis Social Frailty

Received: 11 June 2025;  Published: 29 October 2025;  doi: 10.21926/obm.icm.2504047

Abstract

Across the globe, countries are facing an ageing boom, with the proportion of the older adult population growing compared to younger age groups because of increased life expectancy and declining birth rates. Along with the ageing boom, there is increased interest in the wellbeing of older adults. Healthy ageing and social frailty are two constructs that have emerged in studying older adults and their quality of life. In this paper, we critically review salient literature defining and describing healthy ageing and s [...]

716 2656

Open Access Interview

An Interview with Prof. Dr. Hanuman Singh Jatav

Received: 26 October 2025;  Published: 27 October 2025;  doi: 10.21926/aeer.2504030

509 2627

Open Access Concept Paper

Movement-informed Breathwork (MiB): Integrating Muscular Contractions with Slow Conscious Connected Breathing for Therapeutic Application

Received: 28 July 2025;  Published: 22 January 2026;  doi: 10.21926/obm.icm.2601006

Abstract

This paper introduces Movement-informed Breathwork (MiB), a personalised breath-body approach with biofeedback that integrates a form of conscious connected breathwork (breathing without pauses) with targeted neuromuscular contraction and relaxation cycles. Drawing from neuromuscular torque chain dynamics, fascial research and sensorimotor trauma therapy principles, MiB aims to enhance autonomic regulation, interoceptive awareness and somatic-emotional integration by bridging traditional breathwork (deep, slow-pace [...]

496 2617

Open Access Editorial

Acknowledgment to Reviewers of OBM Integrative and Complementary Medicine in 2024

Received: 03 January 2025;  Published: 03 January 2025;  doi: 10.21926/obm.icm.2501001

Abstract

The editors of OBM Integrative and Complementary Medicine would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2024. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers can download a certificate of recognition directly from our submission system. Additionally, revie [...]

523 2609

Open Access Editorial

Acknowledgment to Reviewers of OBM Neurobiology in 2024

Received: 03 January 2025;  Published: 03 January 2025;  doi: 10.21926/obm.neurobiol.2501262

Abstract

The editors of OBM Neurobiology would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2024. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers can download a certificate of recognition directly from our submission system. Additionally, reviewers can sign up to the Web of [...]

518 2596

Open Access Editorial

Acknowledgement to Reviewers of OBM Transplantation in 2024

Received: 02 January 2025;  Published: 02 January 2025;  doi: 10.21926/obm.transplant.2501229

Abstract

The editors of OBM Transplantation would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2024. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal’s editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers can download a certificate of recognition directly from our submission system. Additionally, reviewers can sign up to t [...]

492 2571

Open Access Editorial

Life Sciences Worldwide – Global Perspectives and Networking for International Professionals1

Received: 15 October 2025;  Published: 16 October 2025;  doi: 10.21926/obm.icm.2504044

Abstract

The International Exchange of Professionals – Thematic Event in Life Science, held on October 15-17, 2025, in Nice, France, inaugurated a global congress series focused on frontier topics in biomedical sciences. This editorial summarizes the first day of the event, including the opening ceremony, keynote forum, and welcome banquet. With more than 150 participants from over 35 countries, the event created a platform for cross-disciplinary exchange and collaboration. Key themes included translational medicine, neurom [...]

668 2540

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