by Rotu Arientare Rume  , Oyovwi Mega Obukohwo  , Ohwin Peggy Ejiro  and Oyelere Abosede Oreoluwa

Received: 04 December 2023;  Published: 27 February 2024;  doi: 10.21926/obm.icm.2401015

Regular physical activity has been proven to improve metabolism, slow aging, and decrease the likelihood of various health conditions such as obesity, type 2 diabetes, and cardiovascular disorders. Hence, dancing was evaluated for its effects on cardiovascular, liver enzymes, and biochemical markers among healthy adults. Forty (40) healthy adults (20-40 years old) were chosen for the study, with an average age calculated. Those with certain health conditions or habits were not allowed to participate. Twenty (20) me [...]

by Morkoss M. Fakhry  , Asmaa R. Abdel-Hamed  , Noha M. Mesbah  , Dina M. Abo-Elmatty  , Mohamed M. Sayed-Ahmed  , Abdel-Moneim M. Osman  and Ola S. Ahmed

Received: 27 November 2023;  Published: 26 February 2024;  doi: 10.21926/obm.genet.2401215

Breast cancer (BC) is the most common cause of cancer-related death and is the malignancy most frequently diagnosed in females worldwide. BC incidence is predicted to continue increasing worldwide. Without interventions, annual new cases will reach over 3 million by 2030. Genetic abnormalities account for almost 70% of all BC cases worldwide. Biological pathways implicated include non-coding RNAs (ncRNAs). MiRNAs are small non-coding RNA molecules that play a role in post-transcriptional regulation of gene expressi [...]

by Fatemeh Mollaamin  and Majid Monajjemi

Received: 27 November 2023;  Published: 21 February 2024;  doi: 10.21926/obm.genet.2401214

As proof has recommended a close connection between COVID-19 and neurodegenerative disorders, this article aims to investigate the chloroquine (CLQ) drug as the SARS-CoV-2’s primary protease, which can prevent in vitro viral duplication of all diverse experiments to present. CLQ is an anti-viral drug enlarged by Pfizer, which can operate as an orally effective 3C-like protease inhibitor. In this study, CLQ has been assessed for its effectiveness against coronavirus by trapping it within a boron nitride nanoca [...]

by Sue Westwood  , Trish Hafford-Letchfield  and Jemma James

Received: 16 October 2023;  Published: 21 February 2024;  doi: 10.21926/obm.geriatr.2401270

Research suggests health, social care, and social work professionals who are highly religious, and adhere closely to traditional doctrine, are more likely to take a negative view of LGBTQ people. This includes those who provide services to older people. Negative attitudes towards lesbian, gay, bisexual, trans and/or queer (LGBTQ) people can translate into poor care and even abuse. This commentary discusses recent literature on older LGBTQ people’s experiences of religious abuse. It highlights the concerns among man [...]

by Jose Benavides  , Pushpesh Sharma  , Ahmed Al Saedi  and Shah Kabir

Received: 20 November 2023;  Published: 21 February 2024;  doi: 10.21926/jept.2401007

This article outlines an innovative approach to explore thermal energy extraction for power generation or industrial hot water applications. Unlike traditional steady-state models, this approach embraces time-variant scenarios, explicitly incorporating a cyclical fluid circulation strategy to maintain a stable surface fluid temperature or power output. By introducing an increasing and decreasing stepwise rate sequence and an intermittent circulation strategy, the method aims to optimize efficiency in response to va [...]

by Gerasimos Rigatos  , Pierluigi Siano  , Mohammed AL-Numay  , Masoud Abbaszadeh  and Gennaro Cuccurullo

Received: 16 September 2023;  Published: 21 February 2024;  doi: 10.21926/jept.2401006

This article aims to treat the nonlinear control problem for the complex dynamics of a wave energy unit (WEC) that consists of a Permanent Magnet Linear Synchronous Generator (PMLSG) and a Voltage Source Converter (VSC). The article has developed a globally stable nonlinear optimal control method for this wave power generation unit. The new method avoids complicated state-space model transformations and minimizes the energy dispersion by the control loop. A novel nonlinear optimal control method is proposed for the [...]

by John Hanna

Received: 30 April 2023;  Published: 21 February 2024;  doi: 10.21926/rpm.2401006

The main weakest point of concrete is its exposure to cracks, and concrete structure repair is expensive, especially for infrastructure maintenance, which is difficult to access. The ability of self-healing concrete (SHC) to successfully heal fractures without the assistance of humans has received much attention since it increases operational life and lowers maintenance expenses. This paper reviews various techniques and technologies of autogenous and autonomous self-healing concrete. Much more attention is given t [...]

by Akingbolabo Daniel Ogunlakin  , Oluwafemi Adeleke Ojo  , Chimzi David Onu-Boms  , Oluwafemi Samson Afolayan  , Peluola Olujide Ayeni  , Idayat Adeola Akinwumi  , Opeyemi Josephine Akinmurele  , Great Oluwamayokun Adebodun  , Damilare Iyinkristi Ayokunle  , Owoola Azeezat Ambali  , Omolola Adenike Ajayi-Odoko  , Oluwaseun Abigael Ogunlakin  and Mubo Adeola Sonibare

Received: 20 November 2023;  Published: 20 February 2024;  doi: 10.21926/obm.genet.2401213

Polycystic ovarian syndrome (PCOS) is a prevalent endocrine illness that affects 5-10% of reproductive women globally. It is a multifaceted hormonal disorder characterized by the involvement of numerous molecular mechanisms that contribute to its development. This study investigates the effect of Artocarpus communis seed on the hormonal imbalance and P53, IRS, HsD17β2, FTO, and CYP11a genes expression in the ovaries of letrozole-induced polycystic ovarian syndrome rats. To induce PCOS in 30 female Wistar rats, [...]

by Onix Cantres-Fonseca  , Shambhu Aryal  , Christopher King  and Steven D. Nathan

Received: 25 May 2023;  Published: 20 February 2024;  doi: 10.21926/obm.transplant.2401207

Chronic allograft dysfunction (CLAD) is one of the leading causes of death after lung transplantation [1]. CLAD is a progressive and irreversible decline in lung function after transplant, manifested as an obstructive, restrictive, or mixed ventilatory impairment without any identifiable etiology as infection or acute rejection. Multiple risk factors have been associated with this condition. Despite its significant effect on the mortality of transplanted patients, there is still a lack of powerfully effective thera [...]

by Tammy S. Martin

Received: 17 December 2023;  Published: 19 February 2024;  doi: 10.21926/obm.geriatr.2401269

Clinicians caring for patients, especially those with chronic diseases or older adults, need to recognize the value of being able to transition away from aggressive care when appropriate and focus on a more palliative approach. Research has shown that patients want to have goals of care discussions and maintain autonomy at the end of life. These goals of care discussions can be challenging, and clinicians must prioritize and develop this skill in order to provide their patients with what they may need most. Being a [...]

by Ludek Fiala

Received: 25 August 2023;  Published: 18 February 2024;  doi: 10.21926/obm.icm.2401014

This research focused on two age groups of men (under 40 and over 40 years) and their sexual function during the COVID-19 pandemic. Somatic examinations, including the measurement of hormone levels, were conducted on all patients. The subjects also completed two questionnaires and provided personal history data. The first questionnaire covered the evaluation of erectile function, while the second assessed psychosocial trauma and stress. The results in the first group (men under 40 years of age) showed a correlation [...]

by Jessica White  and Tom Deweerdt

Received: 28 July 2023;  Published: 17 February 2024;  doi: 10.21926/aeer.2401007

Carbon management is imperative to curb global temperature increases and mitigating climate change impacts. This report explores the carbon management strategies employed by Diebold Nixdorf, a multinational financial and retail technology company. As of 2021, the company has not established specific reduction targets and has not committed to achieving net zero emissions. The company employs diverse carbon reduction strategies, such as carbon offsetting, solar energy, and fleet improvements, with notable projects li [...]

by Nazrien M.D Nazrien  , Novitri  , Tertianto Prabowo  and Farida Arisanti

Received: 14 September 2023;  Published: 17 February 2024;  doi: 10.21926/obm.neurobiol.2401211

Balance is the ability to move and/or preserve a particular position while not falling under external force. Human balance is a complex process of integration and coordination of the sensory, motor, and biomechanical components, which is influenced by intrinsic and exogenous factors. One inherent factor that is hypothesized to have an impact on balance is cognition. However, studies about cognition's role in balance control are still limited, and study literature is needed to gain a better understanding. Cognition [...]

by Ajay Risal  , Dipak Kunwar  and Barsha Shrestha

Received: 21 December 2023;  Published: 08 February 2024;  doi: 10.21926/obm.geriatr.2401268

This paper discusses the impact of Depression on the aging population. It also tries to explore the psychosocial risk factors and burden associated with geriatric depression in low-and-middle-income (LAMI) countries. Nepal, a South Asian developing country, is resource-poor and research-naïve. Research, in general, and mental health studies, in particular, are the least prioritized in this country. The lack of culturally adapted psychiatric inventories is one of the possible reasons for the low number of mental hea [...]

by Dimitrios N. Konispoliatis

Received: 09 December 2023;  Published: 07 February 2024;  doi: 10.21926/jept.2401005

The main challenge in designing offshore renewable energy structures is to ensure their structural integrity on a life cycle basis while operating in harsh environments and, in parallel, being financially competitive and environmentally friendly concerning other types of energy systems. The Oscillating Water Column (OWC) converters are among the first energy converters to be developed and deployed into the sea due to their relative simplicity of operation and relatively small number of moving parts. This review pro [...]

by Spiros Koutandos

Received: 21 October 2023;  Published: 07 February 2024;  doi: 10.21926/rpm.2401005

In this paper, we continue our previous work by discussing the consequences of curvature in spacetime caused by the presence of mass and the implications of this. We address the question raised by Dirac regarding the impact of a magnetic monopole on the quantum world. We discuss quantization concerning the solid angles observed, which may have a connection with a magnetic monopole.

by Angelo Plastino  , Diana Monteoliva  and Angel Ricardo Plastino

Received: 14 October 2023;  Published: 06 February 2024;  doi: 10.21926/rpm.2401004

Collective effects are a typical nuclear feature that refers to the behavior of a group of N fermions (protons and neutrons) within the atomic nucleus. Our interest lies in light nuclei only. Thus, we consider here, using the Lipkin model, a small-N fermion system at low-temperature T and discover -collective phenomena. Our fermion-model simplicity allows one to gain insight into collective fermion behavior. We focus attention, for N<20, on several quantifiers. These include standard ones related to thermal [...]

by Ashraf Zaghwan  , Yousef Amer  , Mahmoud Efatmaneshnik  and Nagi Abdussamie

Received: 24 July 2023;  Published: 06 February 2024;  doi: 10.21926/jept.2401004

The economic impact of energy loss stemming from end-user electricity consumption is a significant concern, with historical trends revealing escalating costs. Effectively managing both peak and off-peak demands remains a formidable challenge due to the unpredictable nature of consumer behaviors, leading to energy wastage. This study delves into the nexus of demand uncertainty, financial repercussions, and potential strategies to mitigate energy losses in the evolving landscape of electricity consumption.that causes [...]

by Sarah I. Willi  , Ulrike Bacher  , Marie Noelle Kronig  , Michael Daskalakis  , Lia Bally  and Thomas Pabst

Received: 29 July 2023;  Published: 04 February 2024;  doi: 10.21926/obm.transplant.2401206

Malnutrition remains a clinical challenge in AML patients undergoing autologous hematopoietic stem cell transplantation (ASCT), leading to physical deconditioning and prolonged hospitalization. Prospective data are mainly lacking to identify those patients who may particularly benefit from parenteral nutrition in this setting. This observational, non-randomized, retrospective, exploratory cohort study assessed the nutritional development in patients following high-dose chemotherapy (HDCT) with ASCT and explored the [...]

by Thaninee Prasoppokakorn  , Supachaya Sriphoosanaphan  , Nutbordee Nalinthassanai  , Thitaporn Roongrawee  , Pongtorn Hanboonkunupakarn  , Pisit Tangkijvanich  and Rungsun Rerknimitr

Received: 08 December 2023;  Published: 02 February 2024;  doi: 10.21926/obm.icm.2401013

Reports indicate that Andrographolide inhibits viral replication and reduces COVID-19 symptoms. This study aimed to determine Andrographolide's additional effect and safety in mild COVID-19 patients treated with favipiravir. A multicenter, open-labeled, randomized controlled trial was conducted from October 2021 to February 2022. The patients were randomized to receive a combination of Andrographolide and favipiravir or favipiravir monotherapy. The primary outcome was the occurrence rate of severe pneumonia. The se [...]

by Varrassi Giustino

Received: 01 February 2024;  Published: 02 February 2024;  doi: 10.21926/obm.neurobiol.2401210

Neurobiology is an expansive field of studies encompassing the nervous system's anatomical and physiological aspects [1]. This complex framework's deep study and understanding have facilitated a more intricate comprehension of the interconnections among various nervous system components implicated in pain perception, transmission, modulation, and adaptation.

by Mohsen Akbaribazm

Received: 27 September 2023;  Published: 31 January 2024;  doi: 10.21926/obm.genet.2401212

The escalating prevalence of vision loss due to eye diseases has instigated a quest for innovative therapies, given that conventional approaches often fall short in repairing and regenerating damaged eye tissues, particularly the retina. Stem cell-based interventions have emerged as a promising avenue, with numerous studies in animal models and human trials exploring their potential to enhance visual acuity. Beyond addressing conditions like age-related macular degeneration (AMD) and diabetic retinopathy (DR), stem [...]

by E. García – Quismondo  and A. Guillermo Bracamonte

Received: 14 October 2023;  Published: 31 January 2024;  doi: 10.21926/rpm.2401003

This communication was brief to show how high conjugated carbon-based structures and carbon allotropes could participate as electron shuttles, semiconductors, quantum emitters, and Optoelectronic processors within confined nanostructured organized systems. In particular, it was focused on nanoassemblies such as vesicles, micelles, and lipidic nanoparticles and incorporated insights from other types of nanomaterials that could afford to develop new organized systems. In these cases, the term organized system was use [...]

by Claire Robson  , Jen Marchbank  and Gloria Gutman

Received: 27 November 2023;  Published: 31 January 2024;  doi: 10.21926/obm.geriatr.2401267

Though research suggests that older adults belonging to gender and sexual minorities (GSM) are at greater risk of abuse and neglect, more needs to be done to investigate this situation, provide solid data, offer support to survivors and better inform those providing services. This article reports on a participatory action research project in which nine older adults with lived experience of abuse were interviewed, as were the seniors’ programmer from our community partner organization and a trauma counsellor who sup [...]

by Adam Resnick  , Alicia Bergman  , Rebecca Oberman  , Stephanie L. Taylor  , Emmeline Chuang  , Kelsey Cummings  and Evelyn T. Chang

Received: 20 December 2023;  Published: 31 January 2024;  doi: 10.21926/obm.icm.2401012

The Veterans Health Administration (VA) offers complementary and integrative health (CIH) therapies to Veterans with chronic pain and opioid use disorder (OUD). While CIH therapies have known benefits for chronic pain, less research exists on its use for patients with OUD. In this qualitative study, we aimed to assess provider and patient perceptions of CIH therapies for Veterans with OUD. We interviewed 45 providers involved in OUD care and 17 Veterans with OUD from five VA medical centers as part of a larger mixe [...]