by Jennifer Marchbank  , KJ Reed  , Claire Robson  , Gloria Gutman  and Balbir Gurm

Received: 04 January 2024;  Published: 18 March 2024;  doi: 10.21926/obm.geriatr.2401274

Elder abuse occurs to older adults who are members of gender and sexual minorities (GSM). Whilst most of that abuse is similar to that experienced by their heterosexual and cisgender peers GSM older adults face particular vulnerabilities due to their life experiences and changes. In this article we report on our findings from a literature search and knowledge synthesis, conducted as part of a larger project to inform Canadian policy makers working to eliminate gender and sexuality-based inequalities. The review inc [...]

by Alhayat Getu Temesgen  , Ömer Fırat Turşucular  and Elif Dicle Turşucular

Received: 12 December 2023;  Published: 15 March 2024;  doi: 10.21926/rpm.2401008

This mini-compilation study included the chemical structure, mechanical, thermal, and dimensional properties of silk fiber, its production process, pre-treatment, and biomedical applications from various experimental studies, which are compiled and summarized. The silk fiber should have a degumming process before using biomedical applications. The 25% concentration for Na2CO3 in ethanol solution (80%) as a coagulant chemical with a salt such as LiB2 (9 M) at a temperature of 98°C for 45 minutes at pH between 6 [...]

by Carsten Croonenbroeck  and David Hennecke

Received: 06 February 2024;  Published: 15 March 2024;  doi: 10.21926/jept.2401008

We address the Wind Farm Layout Optimization (WFLO) problem and tackle the optimal placement of several turbines within a specific (wind farm) area by incorporating additional aspects of an economically driven target function. With this, we contribute three refinements for WFLO research: First, while many research contributions optimize the turbines' locations subject to maximum energy production or energy efficiency, we instead pursue a strategy of maximizing a profit objective. This enables us to incorporate inne [...]

by Jeronimo Kreiker  , Melina Gomez  , Lucas Peisino  , Nelio Ochoa  and Belen Raggiotti

Received: 18 October 2023;  Published: 15 March 2024;  doi: 10.21926/rpm.2401007

It is possible to revalue the plastic fraction from WEEE using it as a recycled aggregate (RA) in cement mortars. However, this feasibility depends on elaborating a granular material via a core-shell strategy to stabilize the potential contaminants. The core is a plastic particle, and the shell is a cement, fillers, and activated carbon mixture. Due to the hydrophilic characteristics of the shell and the presence of interstitial sites generated by the use of the RA, it is necessary to study the wetting properties o [...]

by Ampere A. Tseng

Received: 21 January 2024;  Published: 13 March 2024;  doi: 10.21926/obm.icm.2401019

The aim of this article is to provide a quantitative assessment of the correlation between heightened mindfulness and stress reduction among cancer patients and survivors who engaged in Mindfulness-Based Stress Reduction (MBSR) interventions. Utilizing data from eight studies, we conducted quantitative analyses to provide the effectiveness scores of MBSR interventions on mindfulness, assessed using the Mindful Attention Awareness Scale (MAAS), and stress symptoms, evaluated through standardized self-reported questi [...]

by Sintija Strautmane  , Arturs Balodis  , Klavs Smidrovskis  and Kaspars Auslands

Received: 10 January 2024;  Published: 13 March 2024;  doi: 10.21926/obm.neurobiol.2401214

Rhinorrhea is a possible complication after different types of traumatic brain injury or neurosurgical procedures, such as skull base operations. Pneumocephalus is a rarely noted complication after severe traumatic brain injury, and it may be accompanied by meningitis and ventriculitis, especially when treatment has been delayed. Treatment of these entities includes conservative and surgical approaches. Pneumocephalus may result in neurologic disturbances threatening a life. Therefore, active patient management wit [...]

by Mimi Mun Yee Tse  , Shamay Sheung Mei Ng  , Vivian Lou  , Raymond SK Lo  , Daphne Sze Ki Cheung  , Paul H Lee  , Shuk Kwan Tang  , Siu Hang Leung  and Percy Poo-See Tse

Received: 11 March 2024;  Published: 12 March 2024;  doi: 10.21926/obm.neurobiol.2401213

CorrectionCorrection: Tse et al. How COVID-19 Ceases All Older Adult Services & the Way Out for Community-Dwelling Older Adults with Chronic Pain. OBM Neurobiology 2023; 7: 183Mimi Mun Yee Tse 1, *, Shamay Sheung Mei Ng 2, Vivian Lou 3, Raymond SK Lo 4, Daphne Sze Ki Cheung 5, Paul H Lee 6, Shuk Kwan Tang 7, Siu Hang Leung 1, Percy Poo-See Tse 1* Correspondence: Mimi Mun Yee Tse; E-Mail: mmytse@hkmu.edu.hkAcademic Editors: Ines Testoni, Adriano Zamperini and Lorenza PalazzoSpecial Issue: How COVID-19 Changed Indi [...]

by Giuseppe Cocco  , Hans Peter Hofmann  and Stefano Pandolfi

Received: 27 December 2023;  Published: 11 March 2024;  doi: 10.21926/obm.geriatr.2401273

Heart failure is one of the major health threats in Western societies, and its prevalence is steadily increasing. Many data show the important impact of sex (biological) and gender (sociocultural) differences on most aspects (diagnosis, etiology, treatments, and outcomes) of heart failure. For example, compared to men, women with heart failure are older, have more co-morbidities, and develop different phenotypes of heart failure. Postpartum cardiopathy is unique in women. The iatrogenic effects of cancer therapies [...]

by Bruno A Lima

Received: 15 December 2023;  Published: 11 March 2024;  doi: 10.21926/obm.transplant.2401208

Human Leucocyte Antigens (HLA) constitute a highly polymorphic set of genes pivotal to the immune response. The HLA heterozygous advantage hypothesis assumes that heterozygous individuals at the HLA level have a wider range of peptides for T cell recognition than homozygous individuals. Consequently, they possess an enhanced capacity to trigger a targeted immune reaction. The divergent allele advantage hypothesis is an extension of heterozygous advantage, considering the excessive sequence divergence between allele [...]

by Edmundo S. Valerio Neto  , Caio V.S. Almeida  , Giancarlo R. Salazar-Banda  and Katlin I.B. Eguiluz

Received: 24 November 2023;  Published: 11 March 2024;  doi: 10.21926/cr.2401003

In this study, we synthesized Pt-Rh nanowires (NWs) through chemical reduction of metallic precursors using formic acid at room temperature, excluding the use of surfactants, templates, or stabilizing agents. These NWs were supported on two substrates: carbon (Vulcan XC-72R) and carbon modified with tin oxide (SnO2) via the sol-gel method (10 wt.% SnO2). We explored the electroactivity of Pt/SnO2/C, Pt-Rh/C, Pt-Rh/SnO2(commercial)/C (commercial SnO2), and Pt-Rh/SnO2/C NWs toward electrochemical oxidation of ethanol [...]

by Nadia A. Abdelmegeed Abdelwahed  , Mohammed A. Al Doghan  and Bahadur Ali Soomro

Received: 13 November 2023;  Published: 11 March 2024;  doi: 10.21926/obm.neurobiol.2401212

In this study, the researchers explore the effects of COVID-19-related challenges, such as fear and anxiety about COVID-19, the uncertainty of COVID-19, and the recognition of business opportunities for entrepreneurial intentions and business startups. This study used quantitative methods and based their findings on 278 usable samples collected from Egyptian entrepreneurs. Employing the Structural Equation Model (SEM) through SmartPLS4 shows that fear and anxiety arising from the COVID-19 pandemic harm entrepreneur [...]

by Firas AL-Rshoud  , Lina Almahmoud  , Nagham Younis  , Rnad AL. Ajarmeh  and Ahmad M. Fares

Received: 02 January 2024;  Published: 07 March 2024;  doi: 10.21926/obm.genet.2401222

This study aims to assess the Trophectoderm (TE) biopsy practice in Jordan in terms of the following effectiveness parameters: timing of zona breaching, risk of inner cell mass herniation if zona breaching was done on day 3, timing of TE sampling, method of biopsy (pulling or flicking), number of laser pulses, assessment of embryo survival after biopsy, and degeneration rate. An online cross-sectional survey was conducted in November 2022. The collected data presented the perception of embryologists (>10 years e [...]

by Mohsen Akbaribazm  , Elnaz Khordad  and Mohsen Rahimi

Received: 27 September 2023;  Published: 06 March 2024;  doi: 10.21926/obm.genet.2401221

Various factors contributing to male infertility include genetic determinants, hormonal/neurological imbalance, erectile/libido disorders, genital tract injuries, and toxic/ischemic testicular injuries. Herbs increase sperm count and quality parameters, as well as sexual performance in infertile men, through various mechanisms. For this purpose, efforts were made to investigate effective plants in treating infertility, focusing on those studied in animal research. In this review, we explored the latest findings fro [...]

by Yiu Lin Wong  , Jialing Zhang  , Linda LD Zhong  , David Moher  and Zhaoxiang Bian

Received: 04 December 2023;  Published: 06 March 2024;  doi: 10.21926/obm.icm.2401018

The modified Jade Wind-Barrier formula (MJWB) may prevent the common cold in the elderly with a Qi-deficiency Constitution. Previously, no controlled trial evidence existed to illuminate the concept of “preventive treatment of disease” as outlined in the constitution theory of Traditional Chinese Medicine. This theory distinctly suggests that enhancing the Qi-deficiency Constitution and modulating its functional state can prevent the occurrence of the common cold. This controlled trial (ClinicalTrials.gov identifie [...]

by Gohar Azhar  , Melodee Harris  , Laura Hays  , Patricia Savary  , Regina V. Gibson  , James R Perry  , Karen Coker  , Amanda Pangle  , Kenneth Alderson  and Jeanne Wei

Received: 08 January 2024;  Published: 06 March 2024;  doi: 10.21926/obm.geriatr.2401272

The COVID-19 pandemic caused abrupt changes in daily routines, social connections, and ways of life. It is yet unknown the full impacts these extended changes have had on the long-term mental well-being of those who shared this global experience. As a contribution to our overall understanding of this phenomena, this study explored the effects of the COVID-19 pandemic on the mental well-being of older adults in the Southern United States. Secondary data analyses were performed using the COVID-19 Emotional Impact Sur [...]

by Khaliunaa Bayanbold  , Noel N. Tolbanen  , John A. Bernat  and Jaime Nagy

Received: 30 December 2023;  Published: 05 March 2024;  doi: 10.21926/obm.genet.2401220

Potocki-Lupski syndrome (PTLS) is a recurrent microduplication syndrome characterized by developmental delay, behavioral abnormalities, mildly dysmorphic facial features, hypotonia, and sleep disorders. We report here a 3-year-old girl diagnosed with mosaic PTLS harboring a supernumerary marker chromosome containing the RAI1 (retinoic acid induced 1) gene. Cytogenetic testing, including chromosomal microarray, karyotype, and FISH analysis, identified a ring chromosome containing portions of chromosomes 14 and 17 in [...]

by Milky Mittal  , Annu Kumari  , Bhashkar Paul  , Adya Varshney  , Bhavya  , Ashok Saini  , Chaitenya Verma  and Indra Mani

Received: 07 October 2023;  Published: 04 March 2024;  doi: 10.21926/obm.genet.2401219

Gene therapy involves either the direct introduction of genetic material (DNA or RNA) into the host cell (or organ), known as in vivo gene therapy, the re-introduction of the modified target cells taken out of the host, or ex vivo gene therapy. Cancer is mainly caused by the non-functioning of genes required for normal cell proliferation, and it has emerged as the leading cause of death globally due to the absence of efficient and safe therapies as well as early diagnostic modalities. Therapeutic trials using gene [...]

by G. S. N. V. K. S. N. Swamy Undi  and Rohit Kantikar

Received: 07 September 2023;  Published: 01 March 2024;  doi: 10.21926/aeer.2401009

Particulate matter (PM) constitutes a significant risk factor for environmental health regarding ambient air quality. An epidemiological investigation has determined that inadequate air quality is associated with the development of lung and cardiovascular diseases, chronic ailments, respiratory infections, and a significant number of fatalities on a global scale. According to the World Health Organization (WHO), the annual mortality rate due to air pollution is around 7 million individuals. The necessity for resear [...]

by Shelby Rubino  and Rodger K. Bufford

Received: 03 December 2023;  Published: 29 February 2024;  doi: 10.21926/obm.icm.2401017

In 2019 the novel coronavirus spread quickly throughout the world. It was easily transmitted, resulting in a sudden increase in infection and death rates that overwhelmed hospitals. This sudden pandemic resulted in government and health officials mandating physical and social quarantines to decrease the spread of COVID-19. All these unexpected factors induced traumatic stress across the world. The impact of this trauma is seen to date, as many studies reported adverse mental health effects in an array of population [...]

by Joana Sousa

Received: 05 October 2023;  Published: 29 February 2024;  doi: 10.21926/aeer.2401008

The consistent associations between dampness and health-related problems, such as allergies and asthma symptoms, explain the growing scientific interest in assessing housing characteristics. Due to a growing interest in the built environment, the present study performed a systematic review to investigate the prevalence of dampness related to specific building characteristics. The built environment is gaining significance in population well-being due to the substantial time spent indoors. This aspect is especially n [...]

by Tkachuk Elena Anatolyevna  and Kurenkova Galina Vladimirovna

Received: 15 October 2023;  Published: 28 February 2024;  doi: 10.21926/obm.genet.2401218

This work describes a clinical case of a violation of sex formation in a newborn child with Y-chromosome dysomy. The diagnostic challenges related to Y-chromosome variability and associated anomalies in sex development are being considered. The work presents clinical and laboratory data for Y-chromosome dysomy. It is noted that the challenge in diagnosing disorders of sex development is associated with the polymorphic clinical manifestations of this syndrome. It is noted that the presence of Y-chromosome dysomy is [...]

by Laura Roche  , Traci Flynn  and Linda Campbell

Received: 26 September 2023;  Published: 28 February 2024;  doi: 10.21926/obm.genet.2401217

22q11.2 deletion syndrome (22q11.2DS) is a complex and widely variable genetic syndrome involving multisystem physical health problems, significant cognitive and psychosocial challenges, all of which may impact upon learning and academic achievement. In the current study, we explored mothers’ perceptions of their child’s learning within early and primary educational contexts. We conducted 3 online focus groups and 1 online semi-structured interview with a total of 9 mothers of children diagnosed with 22q11.2DS. Mot [...]

by Dicky Moch Rizal  , Ika Setyawati  , Arya Adiningrat  , Agus Widiyatmoko  , Supriyatiningsih  and Nandia Septiyorini

Received: 09 October 2023;  Published: 27 February 2024;  doi: 10.21926/obm.genet.2401216

Y chromosome microdeletions (YCMs) are one kind of genetic disorder that contributes to male infertility. This study aims to determine the profile of YCMs in the infertile male population in Indonesia. This cross-sectional study was conducted by identifying YCMs testing data on 49 infertile male patients identified with azoospermia and oligoasthenoteratozoospermia (OAT) based on their sperm analysis, who visited andrology polyclinics in several hospitals in Yogyakarta Province between March 2021 to August 2022. Stu [...]

by Toku Takahashi

Received: 28 August 2023;  Published: 27 February 2024;  doi: 10.21926/obm.icm.2401016

In modern society, depression is one of the most common mental disorders. It is generally thought that depression is due to the disorders of neuronal circuits and chemical balance in the brain. Patients with depression often receive treatment with selective serotonin reuptake inhibitors (SSRIs). However, recent studies suggest that the magnitude of benefit of pharmacological treatment is quite limited for these patients. Although recent studies propose acupuncture as a non-pharmacological approach to managing depre [...]

by Marta Evelia Aparicio-García  and Roberto Andrés Lasso Báez

Received: 06 November 2023;  Published: 27 February 2024;  doi: 10.21926/obm.geriatr.2401271

Older trans people have been largely unaddressed both in the context of the LGBTIQ+ community and in studies on geriatrics and aging. This literature review compiles up-to-date information on transgender elders, providing a summary of the Spanish historical context in which trans people have been raised, and analyzes the areas in which to center possible courses of action and research on a global scale. The themes tackled are the presence of victimization and violence; the effects of medical transition, taking into [...]