by Heidrun Männle  , Birthe Osorio  and Karsten Münstedt

Received: 09 March 2020;  Published: 28 April 2020;  doi: 10.21926/obm.icm.2002024

Palliative care is a steadily growing component of medicine that focuses on treating individuals with life-limiting diseases such as cancer. It aims at improving the quality of life and alleviating cancer-related symptoms, including anxiety, pain, dyspnea, cough, nausea/vomiting, and constipation, which could result in significant physical and mental impairment. Integrative palliative care (IPC), as a subspecialty of palliative care, includes complementary approaches to treat patients holistically in their biopsych [...]

by Pluvinage Guy  and Capelle Julien

Received: 03 March 2022;  Published: 01 September 2022;  doi: 10.21926/jept.2203029

Hydrogen is a dangerous gas due to its low ignition energy, wide flammability range, promotion of the embrittlement of steel, and its high coefficient of permeation for polymers. The fracture toughness and failure elongation of pipe steels are strongly impacted by hydrogen embrittlement, whereas yield stress and ultimate strength are moderately impacted. Specific tools are required for the pipe defect assessment used for the transport of hydrogen, which is pure or blended with natural gas. The safety factors associ [...]

by Leonard A. Jason

Received: 15 October 2024;  Published: 05 February 2025;  doi: 10.21926/obm.neurobiol.2501267

Following mental or physical exertion, patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) experience Post-Exertional Malaise (PEM). Although self-report questions represent less expensive and invasive procedures to assess PEM, variability in the wording of the symptom can cause reliability and validity problems. If different PEM measures are used in studies, this could create difficulties in replicating findings, identifying biomarkers, and determining effective treatments for patients. The o [...]

by Brooks M. Hybertson  , Bifeng Gao  and Joe M. McCord

Received: 21 September 2021;  Published: 10 January 2022;  doi: 10.21926/obm.icm.2201002

There has been a long history of human usage of the biologically-active phytochemicals in Salvia rosmarinus, Zingiber officinale, and Sophora japonica for health purposes, and we recently reported on a combination of those plant materials as the PB123 dietary supplement. In the present work we extended those studies to evaluate activation of the nuclear factor erythroid 2-related factor 2 (Nrf2) transcription factor and differential gene expression in cultured HepG2 (hepatocellular carcinoma) cells treated with PB1 [...]

by Robert Resta

Received: 22 June 2021;  Published: 01 September 2021;  doi: 10.21926/obm.genet.2103136

The goals of prenatal testing remain controversial and reflect competing interests of public health, patient rights, disability activists, scholars, feminist critics, commercial laboratories, judiciary/legislative trends, and medical science. This paper reviews and critiques the most common justifications of prenatal testing for fetal aneuploidy that have been put forth over the half century of its existence: reducing the medical and economic burden to society of genetic disease through selective abortion, allowing [...]

by JeongChul HEO  and Sumi HAN

Received: 15 June 2022;  Published: 08 October 2022;  doi: 10.21926/obm.neurobiol.2204141

This study aimed to verify whether self-directed learning readiness (SDLR) level can be significantly predicted by the literacy of learning management system (LLMS), motivation, and feedback interaction (FI) in non–face-to-face educational settings. We performed Pearson’s correlation analysis and multiple regression analysis. A total of 206 online college students responded to this web survey using simple random sampling. Results showed that three variables (LLMS, motivation, and FI) were positively associated with [...]

by Niamh Flynn

Received: 18 March 2021;  Published: 02 May 2021;  doi: 10.21926/obm.neurobiol.2102092

Although studies to understand the pathogenesis of migraines are in progress, no theory has adequately explained the etiology and pathophysiology of migraines to date. This has affected the development of treatment strategies for migraineurs. Currently, the pharmacological treatment for migraines provides both acute and prophylactic options to patients based on a biomedical model of pain. However, patients’ adherence to oral migraine preventive medication (OMPM) is poor, and their persistence is even lower when the [...]

by Pietro Gareri

Received: 28 February 2022;  Published: 19 May 2022;  doi: 10.21926/obm.geriatr.2202198

The omega-3 long-chain polyunsaturated fatty acids (omega-3 LC-PUFAs) family includes eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), and docosapentaenoic acid (DPA). Although seafood is the richest source of omega-3 LC-PUFAs, because diet alone is often insufficient in older people, they may require food supplements and enriched food as sources of omega-3 LC-PUFAs. It has been reported that long-term intake of 3-5 g/d EPA + DHA as supplements is safe for adults; omega-3 LC-PUFAs exert cardio-metabolic pro [...]

by Ana Pérez-González  and Ismael El Hajra

Received: 17 November 2024;  Published: 13 May 2025;  doi: 10.21926/rpn.2502010

In recent years, the incidence of Inflammatory Bowel Disease (IBD) has risen significantly in the Western population, pointing toward the potential influence of environmental and dietary factors. In order to explain this, some research on nutritional therapy identifies exclusive enteral nutrition (EEN) as a highly effective approach for managing IBD in children. This treatment achieves high remission rates; more specifically, some clinical trials have reported remission rates from 70% to 100%. EEN not only facilita [...]

by Aurélie Laborel-Préneron  , Paulina Faria  , Jean-Emmanuel Aubert  and Camille Magniont

Received: 12 March 2021;  Published: 07 May 2021;  doi: 10.21926/rpm.2102016

Bio-based earth composites present various environmental benefits, such as usable wastes, coproducts, abundant or renewable materials, etc. Moreover, the incorporation of bioaggregates in the earth matrix allows the buildings to act as an effective carbon sink. A growing number of studies are now focusing on the mechanical and hygrothermal properties of bio-based earth building materials. However, the durability of these types of material is a major concern, and knowledge of their various aspects is essential to an [...]