by Inmaculada Zarzo  , Pietro Marco Boselli  , Nadia San Onofre  and Jose M. Soriano

Received: 07 September 2023;  Published: 23 November 2023;  doi: 10.21926/rpn.2304022

Lately, we've witnessed the emergence of obesity as a prominent concern for public health and the economy. This issue commands serious attention, impacting millions worldwide, particularly in the most developed nations. Practical approaches to tackling obesity involve tailored physical activity and dietary interventions overseen by qualified healthcare professionals. Nonetheless, some individuals opt for quicker routes, embracing dietary regimens that promise rapid and effortless weight reduction yet lack substanti [...]

by Mahintaj Dara  , Negin Shafieipour  , Mahsa Saffar  , Mehdi Dianatpour  , Seyed-Mohammad-Bagher Tabei  and Seyed-Alireza Dastgheib

Received: 18 November 2024;  Published: 01 April 2025;  doi: 10.21926/obm.genet.2502289

Since the initial discovery of the CRISPR system in bacteria as an adaptive immune system, a deeper understanding of CRISPR structure and function has made it possible to perform gene editing, gene therapy, and revolutionize the diagnostic field. One of the exciting applications of the CRISPR-Cas system is used as a tool for the rapid diagnosis of infectious diseases and their treatment and the prevention of infection spread among people. The CRISPR-based diagnostic system could be the next-generation standard beca [...]

by Igor Val Danilov

Received: 09 May 2023;  Published: 02 November 2023;  doi: 10.21926/obm.neurobiol.2304192

The theoretical study observes literature to understand whether or not low-frequency oscillations can simultaneously alter the excitability of neurons from peripheral nervous subsystems in different individuals to provide Shared Intentionality in recipients (e.g., fetuses and newborns) and what are the attributes of ecological context for Shared Intentionality. To grasp the perception of objects during environmental learning at the onset of cognition, a fetus needs exogenous factors that could stimulate her nervous [...]

by Gian Andrea Rollandi  , Aldo Chiesa  , Nicoletta Sacchi  , Mauro Castagnetta  , Matteo Puntoni  , Adriana Amaro  , Barbara Banelli  and Ulrich Pfeffer

Received: 31 January 2019;  Published: 05 May 2019;  doi: 10.21926/obm.geriatr.1902051

Aging is associated with an increased incidence of major diseases, including cancer, cardiovascular, neurodegenerative, metabolic and autoimmune diseases. Primary prevention and early diagnosis of these diseases have a dramatic impact on incidence, outcome, quality of life and are commonly applied as age-dependent indications based on evidence of efficacy for specific groups of the aging population. They likely contribute to the observed increase in life expectancy through the reduction of incidence and the retarda [...]

by Asaad G Ishak  , Sundar V Cherukuri  , GianCarlo Diaz  and Richard McCallum

Received: 25 January 2021;  Published: 02 July 2021;  doi: 10.21926/obm.geriatr.2103174

Dysphagia, or difficulty swallowing, is a common condition, especially among the elderly population and can become debilitating. As we age, there are subtle changes in esophageal motility, but by no means is dysphagia ever considered to be a normal result of aging. Dysphagia usually presents with a variety of accompanying symptoms ranging from regurgitation during meals, mild discomfort, to severe chest pain. It can be challenging to localize the dysphagia from the history. The underlying etiology may become eviden [...]

by Kazandra Lopez Hernandez  and John V. Rider

Received: 26 July 2023;  Published: 20 November 2023;  doi: 10.21926/obm.icm.2304053

Chronic pain imposes significant personal and societal challenges. The concerning impact across all population levels has led to several federal agencies dedicating considerable efforts to developing clinically guiding recommendations to improve how chronic pain is addressed, specifically in primary care practice. These guidelines recognize and emphasize the importance of comprehensive evaluation, appropriate diagnosis, and treatment interventions that target multifactorial influences of pain for improved quality o [...]

by Xiaolei Liu  , Yanjie Zhang  , Xiru Du  , Yongzhi Ma  , Ruike Jiang  , Shihui Chen  and Yongtai Wang

Received: 24 September 2022;  Published: 28 January 2023;  doi: 10.21926/obm.icm.2301008

Qigong, a traditional Chinese exercise routine, has been used as a treatment for Parkinson’s disease (PD) in many studies, and the results have confirmed its effectiveness in reducing the symptoms of PD. However, no study has yet investigated the long-term effects and benefits of Qigong practices in improving the symptoms of PD. The purpose of this follow-up evaluation was to investigate the long-term effects of Qigong practices in improving the symptoms of PD. In this randomized controlled trial (RCT), patie [...]

by Gulzhaina K. Kassymova  , Mariam R. Arpentieva  , Bakhyt D. Zhigitbekova  , Hans Schachl  , Aigerim N. Kosherbayeva  , Kundyz Zh. Aganina  , Farid R. Vafazov  , Petr V. Menshikov  , Marina G. Golubchikova  and Andrey I. Korobchenko

Received: 07 March 2023;  Published: 07 November 2023;  doi: 10.21926/obm.neurobiol.2304193

Stressful events in students' and teachers' personal, academic, and professional lives are widespread. The paper discusses many effective methods and techniques for correcting and preventing stress that are simple to learn and practice. They give good results in working with children, adolescents, and youths in training and education. Some practices are more complex and require more attention and effort to understand and master them, but they also have broader capabilities in various situations. Therefore, training [...]

by Kelly Armstrong  , Raman Gokal  and Todd Todorsky

Received: 25 March 2019;  Published: 25 September 2019;  doi: 10.21926/obm.icm.1903056

Background: Direct Current (DC) micro-current point stimulation (MPS) is increasingly recognized as a therapy for chronic pain and stress management. However, there remains limited evidence as to the therapeutic value of MPS in chronic post surgical pain (CPSP) management related to C-Section scars. Objectives: We aimed to determine the effect and magnitude that MPS has when applied to C-section scars and its effects on a wide variety of non-specific chronic post surgical pain syndromes. Study Design: This was a co [...]

by María Izal  , Roberto Nuevo  and Ignacio Montorio

Received: 19 June 2019;  Published: 12 December 2019;  doi: 10.21926/obm.geriatr.1904094

Background: In the last two decades, successful aging (SA) and positive psychology (PP), the two paradigms of health have received great attention. They originate from different approaches, theoretical background, and objectives. Although they share many characteristics, their association remains understudied. This article aims to empirically analyze their possible interrelation. Methods: In this cross-sectional study, 169 healthy, old adults completed several questionnaires to assess the central framework for succ [...]