Red Meat Consumption and Rheumatic Diseases: A Comprehensive Narrative Review
Abstract
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Red Meat Consumption and Rheumatic Diseases: A Comprehensive Narrative ReviewAbstract
Dietary factors influence chronic inflammation and immune regulation, potentially affecting the onset and activity of rheumatic disease. Red meat, a major source of protein, heme iron, and saturated fat, has been linked to metabolic and inflammatory disorders, yet its role in rheumatic diseases remains unclear. To comprehensively evaluate the relationship between red-meat consumption and major rheumatic diseases—including rheumatoid arthritis (RA), gout, systemic lupus erythematosus (SLE), and other inflammatory or [...] 114 276 |
Hydroclimatic Variability and Precipitation Extremes in Sindh under a Changing ClimateAbstract
Sindh Province, Pakistan, is highly vulnerable to hydroclimatic extremes, necessitating a detailed understanding of its precipitation patterns for effective water management. This study assesses spatiotemporal precipitation dynamics across Sindh from 2001 to 2024 by integrating satellite-based CHIRPS data, in situ observations from the Climate Knowledge Portal (CKP), and CMIP6 climate model projections. Validation results show strong agreement between CHIRPS and ground data (R ≈ 0.87, d ≈ 0.93), confirming the sate [...] 75 270 |
Novel Therapies for the Treatment of Antibody Mediated Rejection in Solid Organ Transplantation: A Systematic Reviewby
Abstract
Antibody mediated rejection (AMR) is a considerable cause of late allograft failure in solid organ transplantation. Conventional approaches, using plasmapheresis, intravenous immunoglobulin, rituximab, bortezomib, and eculizumab have been unsuccessful in improving graft survival. This review aims to assess emerging therapies for AMR treatment across all organs. Using a PubMed search, literature published up to July 20, 2025 regarding tocilizumab, clazakizumab, carfilzomib, daratumumab, imlifidase, felzartamab, and [...] 61 248 |
Aversion But Not Aggression: Emotional Traits of KM Rats in Sociability Testsby
Abstract
The inbred Krushinsky-Molodkina (KM) rat strain, characterized by latent genetic epilepsy, reduced social motivation, and a high propensity for freezing, is a promising model for translational research of social deficits in autism spectrum disorder (ASD). In clinical practice, social deficits often lead to social withdrawal and can be accompanied by aggression. It was unknown if KM rats exhibit such aggression during inescapable social encounters. We assessed intraspecific aggression in KM and control rats using th [...] 58 169 |
Examining the Pre-Hospital Workflow of Stroke Patients Referred with Code SAMA (724) and their Outcome in the Emergency Department of Imam Reza Hospital (AS)by
Abstract
The "Sama Code" is a protocol implemented in Iranian pre-hospital emergency services to manage time and treat patients with suspected stroke symptoms based on the FAST criteria. This study aims to analyze the workflow of patients with stroke symptoms transferred under the Sama Code. All patients with neurological symptoms who were brought to Imam Reza Hospital by pre-hospital emergency services after activating the Sama Code during the years 2021 and 2022 were included in the study. Data were collected from pre-hos [...] 39 132 |
Quasi-Solid-State Electrolytes of Polyethylene Oxide-Based Composite Electrolyte with Liquid ElectrolytesAbstract
A thin film of PEO18Li(CF3SO2)2N(LiTFSI)-tetraethylene glycol dimethyl ether (G4)-Li1.4Al0.4Ge0.2Ti1.4(PO4)3-LiCl·H2O (LAGTP·LiCl) was prepared by addition of 1,2-dimethoxyethane (DME). The grain boundary resistance of PEO18LiTFSI-LAGTP·LiCl was considerably reduced by the addition of G4, and a large-sized thin film of the composite polymer electrolyte was prepared easily by the addition of 10 wt.% DME. The electrical conductivity of [(PEO18LiTFSI-2G4)-5 wt.% LAGTP·LiCl]-10 wt.% DME was 1.2 × 10-4 S cm-1 at 25°C, a [...] 32 98 |
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