by Brooks M. Hybertson  , Bifeng Gao  and Joe M. McCord

Received: 21 September 2021;  Published: 10 January 2022;  doi: 10.21926/obm.icm.2201002

There has been a long history of human usage of the biologically-active phytochemicals in Salvia rosmarinus, Zingiber officinale, and Sophora japonica for health purposes, and we recently reported on a combination of those plant materials as the PB123 dietary supplement. In the present work we extended those studies to evaluate activation of the nuclear factor erythroid 2-related factor 2 (Nrf2) transcription factor and differential gene expression in cultured HepG2 (hepatocellular carcinoma) cells treated with PB1 [...]

by Christiano Lima Machado  and Carlos Eduardo Sanches de Andrade

Received: 23 September 2022;  Published: 31 January 2023;  doi: 10.21926/aeer.2301015

The amount of greenhouse gases has been growing dramatically in recent decades, producing global warming and causing climate change that affects the entire planet. To mitigate these emissions, several nations have committed to implementing measures to reduce emissions of these gases, with carbon dioxide being the main one. The transport sector is one of the leading carbon emitters. It needs to be the object of attention from government authorities and private companies so that sustainable solutions are planned and [...]

by Robert Resta

Received: 22 June 2021;  Published: 01 September 2021;  doi: 10.21926/obm.genet.2103136

The goals of prenatal testing remain controversial and reflect competing interests of public health, patient rights, disability activists, scholars, feminist critics, commercial laboratories, judiciary/legislative trends, and medical science. This paper reviews and critiques the most common justifications of prenatal testing for fetal aneuploidy that have been put forth over the half century of its existence: reducing the medical and economic burden to society of genetic disease through selective abortion, allowing [...]

by Sonal Mishra  , Neha Kumari  , Donat-P. Häder  and Rajeshwar P. Sinha

Received: 03 January 2022;  Published: 16 March 2022;  doi: 10.21926/aeer.2201011

Cyanobacteria are the most ancient phytoplankton that first appeared at least 2.5 billion years ago and have a prolonged evolutionary history. They can form impenetrable and toxic blooms in aquatic ecosystems such as freshwater and marine environments. Cyanobacterial blooms produce cyanotoxins that endanger ecosystem functioning and deteriorate water quality used for recreation, drinking, and in fisheries, thus, adversely affecting human health and the economy. Some bloom-producing genera are Aphanizomenon, Plankto [...]

by Gulzhaina K. Kassymova  , Mariam R. Arpentieva  , Bakhyt D. Zhigitbekova  , Hans Schachl  , Aigerim N. Kosherbayeva  , Kundyz Zh. Aganina  , Farid R. Vafazov  , Petr V. Menshikov  , Marina G. Golubchikova  and Andrey I. Korobchenko

Received: 07 March 2023;  Published: 07 November 2023;  doi: 10.21926/obm.neurobiol.2304193

Stressful events in students' and teachers' personal, academic, and professional lives are widespread. The paper discusses many effective methods and techniques for correcting and preventing stress that are simple to learn and practice. They give good results in working with children, adolescents, and youths in training and education. Some practices are more complex and require more attention and effort to understand and master them, but they also have broader capabilities in various situations. Therefore, training [...]

by Inmaculada Zarzo  , Pietro Marco Boselli  , Nadia San Onofre  and Jose M. Soriano

Received: 07 September 2023;  Published: 23 November 2023;  doi: 10.21926/rpn.2304022

Lately, we've witnessed the emergence of obesity as a prominent concern for public health and the economy. This issue commands serious attention, impacting millions worldwide, particularly in the most developed nations. Practical approaches to tackling obesity involve tailored physical activity and dietary interventions overseen by qualified healthcare professionals. Nonetheless, some individuals opt for quicker routes, embracing dietary regimens that promise rapid and effortless weight reduction yet lack substanti [...]

by Pluvinage Guy  and Capelle Julien

Received: 03 March 2022;  Published: 01 September 2022;  doi: 10.21926/jept.2203029

Hydrogen is a dangerous gas due to its low ignition energy, wide flammability range, promotion of the embrittlement of steel, and its high coefficient of permeation for polymers. The fracture toughness and failure elongation of pipe steels are strongly impacted by hydrogen embrittlement, whereas yield stress and ultimate strength are moderately impacted. Specific tools are required for the pipe defect assessment used for the transport of hydrogen, which is pure or blended with natural gas. The safety factors associ [...]

by Aurélie Laborel-Préneron  , Paulina Faria  , Jean-Emmanuel Aubert  and Camille Magniont

Received: 12 March 2021;  Published: 07 May 2021;  doi: 10.21926/rpm.2102016

Bio-based earth composites present various environmental benefits, such as usable wastes, coproducts, abundant or renewable materials, etc. Moreover, the incorporation of bioaggregates in the earth matrix allows the buildings to act as an effective carbon sink. A growing number of studies are now focusing on the mechanical and hygrothermal properties of bio-based earth building materials. However, the durability of these types of material is a major concern, and knowledge of their various aspects is essential to an [...]

by Christopher Thomas  , Matthias Williams  and Oksana A. Shlobin

Received: 07 August 2023;  Published: 11 October 2023;  doi: 10.21926/obm.transplant.2304197

Lung transplantation is a last-resort treatment option for patients with end stage lung disease. The procedure is being performed more frequently and scientific advances continue to be made, but the median post-transplant survival is far shorter than other solid organ transplant recipients. Candidate selection is a resource intensive process that attempts to balance risks of the procedure with the benefits of much higher quality of life. Transplant centers must weigh disease specific considerations, medical comorbi [...]

by Adayabalam S. Balajee

Received: 26 August 2018;  Published: 19 October 2018;  doi: 10.21926/obm.genet.1804042

The technique of in situ hybridization (ISH) using radioactively labeled DNA probes was first described in the late 1960s and early 1970s. The first use of fluorescence in situ hybridization (FISH) was reported in 1980s where RNA labeled with a fluorophore at the 3’ end was used to detect specific DNA sequences. Since then, the technique has undergone various modifications for detecting single genes, chromosomes and whole genomes on various targets such as interphase nucleus, prematurely condensed chromosomes [...]